Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionADP transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

5.29e-1011845GO:0015217
GeneOntologyMolecularFunctionATP transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

2.27e-0914845GO:0005347
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-25 ERVK-10

9.68e-0937846GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-25 ERVK-10

1.15e-0838846GO:0070001
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

3.70e-0823845GO:0005346
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

7.17e-0826845GO:0000295
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

9.40e-0811844GO:0004523
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

1.28e-0729845GO:0015216
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 SLC22A1

1.74e-0759846GO:1901505
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 SLC22A1

1.74e-0759846GO:0015932
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

2.53e-0733845GO:0015215
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

2.82e-0714844GO:0003964
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 REV3L

5.26e-0738845GO:0034061
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

6.01e-0739845GO:0015605
GeneOntologyMolecularFunctionATP:ADP antiporter activity

SLC25A4 SLC25A5 SLC25A6

7.14e-075843GO:0005471
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-8 ERVK-7 ERVK-10

1.65e-0621844GO:0035613
GeneOntologyMolecularFunctionATP hydrolysis activity

MMAA DHX36 KIF6 ATP8A1 RUVBL1 DNAH10 ABCA12 PSMC6 KIF3C SNRNP200

1.60e-054418410GO:0016887
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-8 ERVK-7 ERVK-10

1.73e-0537844GO:0016891
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 RCL1 ERVK-8 ERVK-7 ERVK-10

2.06e-0579845GO:0004521
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1A GABRR1 CACNA1E SLC25A41 SLC25A42 SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC25A6 ABCA12 SLC22A1 SCN3A UNC80 GABRA4

2.83e-0511808416GO:0022857
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-8 ERVK-7 ERVK-10

4.16e-0546844GO:0016893
GeneOntologyMolecularFunctionATP-dependent activity

MMAA DHX36 KIF6 ATP8A1 RUVBL1 DNAH10 MYO7A ABCA12 PSMC6 KIF3C SNRNP200

5.16e-056148411GO:0140657
GeneOntologyMolecularFunctiontransporter activity

CACNA1A GABRR1 CACNA1E SLC25A41 SLC25A42 SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC25A6 ABCA12 SLC22A1 SCN3A UNC80 GABRA4

8.14e-0512898416GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A GABRR1 CACNA1E SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A UNC80 GABRA4

1.16e-047938412GO:0015075
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 DHX36 RUVBL1 ERVK-8 ERVK-7 ERVK-10 REV3L

1.18e-04262847GO:0140097
GeneOntologyMolecularFunctionadenine transmembrane transporter activity

SLC25A4 SLC25A5

1.73e-045842GO:0015207
GeneOntologyMolecularFunctionoxidative phosphorylation uncoupler activity

SLC25A4 SLC25A5

1.73e-045842GO:0017077
GeneOntologyMolecularFunctionpyrophosphatase activity

MMAA DHX36 KIF6 SLC25A42 ATP8A1 RUVBL1 DNAH10 ABCA12 LRRK2 PSMC6 KIF3C SNRNP200

1.96e-048398412GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

MMAA DHX36 KIF6 SLC25A42 ATP8A1 RUVBL1 DNAH10 ABCA12 LRRK2 PSMC6 KIF3C SNRNP200

1.98e-048408412GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

MMAA DHX36 KIF6 SLC25A42 ATP8A1 RUVBL1 DNAH10 ABCA12 LRRK2 PSMC6 KIF3C SNRNP200

1.98e-048408412GO:0016818
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC25A41 SLC25A42 SLC4A8 SLC25A4 SLC25A5 SLC25A6 SLC22A1

2.35e-04293847GO:0008514
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 RCL1 ERVK-8 ERVK-7 ERVK-10

2.73e-04136845GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 RCL1 ERVK-8 ERVK-7 ERVK-10

2.73e-04136845GO:0004519
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

BUD23 ERVK-6 DHX36 RCL1 ERVK-8 ERVK-7 ERVK-10 SNRNP200

3.69e-04417848GO:0140098
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

BUD23 ERVK-6 DHX36 RUVBL1 RCL1 ERVK-8 ERVK-7 ERVK-10 REV3L SNRNP200

3.70e-046458410GO:0140640
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MMAA DHX36 KIF6 ATP8A1 RUVBL1 DNAH10 ABCA12 LRRK2 PSMC6 KIF3C SNRNP200

3.94e-047758411GO:0017111
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 REV3L

4.55e-04152845GO:0016779
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A CACNA1E SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A UNC80

4.65e-046648410GO:0008324
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1E

6.18e-049842GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1E

6.18e-049842GO:0099626
GeneOntologyMolecularFunctionpre-miRNA binding

DHX36 XPO5

6.18e-049842GO:0070883
GeneOntologyMolecularFunctionG-quadruplex RNA binding

DHX36 MCRS1

7.70e-0410842GO:0002151
GeneOntologyMolecularFunctionpurine nucleobase transmembrane transporter activity

SLC25A4 SLC25A5

7.70e-0410842GO:0005345
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC25A42 SLC4A8 ATP8A1 SLC25A4 SLC25A5 SLC25A6 ABCA12 SLC22A1

8.91e-04477848GO:0022804
GeneOntologyMolecularFunctionnucleobase transmembrane transporter activity

SLC25A4 SLC25A5

9.38e-0411842GO:0015205
GeneOntologyMolecularFunctionADP binding

RUVBL1 MYO7A GLUD1

1.08e-0348843GO:0043531
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1A GABRR1 CACNA1E SLC4A8 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A GABRA4

1.28e-037588410GO:0015318
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1E

1.54e-0314842GO:0008331
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF6 DNAH10 MYO7A KIF3C

1.55e-03118844GO:0003774
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC25A42 SLC4A8 SLC25A4 SLC25A5 SLC25A6 SLC22A1

1.56e-03296846GO:0015291
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRR1 SLC4A8 SLC22A1 GABRA4

1.92e-03125844GO:0015108
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ERVK-8 CASP4 ERVK-19 ERVK-7 ERVK-25 ERVK-10

2.23e-03430847GO:0004175
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRR1 GABRA4

2.56e-0318842GO:0022851
GeneOntologyMolecularFunctionantiporter activity

SLC4A8 SLC25A4 SLC25A5 SLC25A6

2.75e-03138844GO:0015297
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRR1 GABRA4

2.85e-0319842GO:0004890
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 RCL1 ERVK-8 ERVK-7 ERVK-10

2.92e-03231845GO:0004518
GeneOntologyMolecularFunctionNAD+ binding

GLUD1 HADHA

3.16e-0320842GO:0070403
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A GABRR1 CACNA1E TRPM3 SCN3A UNC80 GABRA4

3.20e-03459847GO:0005216
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF6 DNAH10 KIF3C

3.21e-0370843GO:0003777
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRR1 SLC4A8 SLC22A1 GABRA4

3.80e-03151844GO:0008509
GeneOntologyMolecularFunctiontau-protein kinase activity

MARK4 MARK2

3.82e-0322842GO:0050321
GeneOntologyMolecularFunctionGABA receptor activity

GABRR1 GABRA4

3.82e-0322842GO:0016917
GeneOntologyMolecularFunctionmagnesium ion binding

DHX36 ATP8A1 LRRK2 MARK2 ADCY2

3.88e-03247845GO:0000287
GeneOntologyMolecularFunctioncyclase activity

RCL1 ADCY2

4.54e-0324842GO:0009975
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1A CACNA1E SLC4A8 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A

4.85e-03627848GO:0022890
GeneOntologyMolecularFunctionG-protein beta/gamma-subunit complex binding

PLCB2 ADCY2

4.93e-0325842GO:0031683
GeneOntologyMolecularFunctioncullin family protein binding

KLHL9 KLHL36

5.32e-0326842GO:0097602
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

GABRR1 SLC4A8 SLC22A1 GABRA4

5.89e-03171844GO:0015103
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ERVK-6 RIOK1 MARK4 LRRK2 ERVK-8 ERVK-7 ERVK-10 MARK2 REV3L LYN

5.91e-039388410GO:0016772
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP8A1 ABCA12

6.16e-0328842GO:0140326
GeneOntologyMolecularFunctionpeptidase activity

TINAGL1 ERVK-6 ERVK-8 CASP4 ERVK-19 ERVK-7 ERVK-25 ERVK-10

6.22e-03654848GO:0008233
GeneOntologyMolecularFunctionchannel activity

CACNA1A GABRR1 CACNA1E TRPM3 SCN3A UNC80 GABRA4

6.62e-03525847GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A GABRR1 CACNA1E TRPM3 SCN3A UNC80 GABRA4

6.68e-03526847GO:0022803
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ERVK-6 PTPRF APMAP RCL1 ERVK-8 PLCB2 ERVK-7 ERVK-10 HMOX1

6.76e-03807849GO:0016788
GeneOntologyMolecularFunctionlaminin binding

TINAGL1 BCAM

8.99e-0334842GO:0043236
GeneOntologyMolecularFunctionpoly(U) RNA binding

MCRS1 PABPC1L

8.99e-0334842GO:0008266
GeneOntologyMolecularFunctiontubulin binding

KIF6 MARK4 LRRK2 SPIRE1 KIF3C LYN

9.34e-03428846GO:0015631
GeneOntologyMolecularFunctionmicrotubule binding

KIF6 MARK4 LRRK2 SPIRE1 KIF3C

9.68e-03308845GO:0008017
GeneOntologyBiologicalProcessADP transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

8.17e-1012855GO:0015866
GeneOntologyBiologicalProcessmitochondrial ADP transmembrane transport

SLC25A41 SLC25A4 SLC25A5 SLC25A6

1.34e-095854GO:0140021
GeneOntologyBiologicalProcesspurine-containing compound transmembrane transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 SLC22A1

1.40e-0840856GO:0072530
GeneOntologyBiologicalProcessmitochondrial ATP transmembrane transport

SLC25A41 SLC25A4 SLC25A5 SLC25A6

1.86e-088854GO:1990544
GeneOntologyBiologicalProcessATP transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

3.35e-0823855GO:0015867
GeneOntologyBiologicalProcessnucleotide transmembrane transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

1.65e-0731855GO:1901679
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-8 ERVK-7 ERVK-10

1.87e-0713854GO:0015074
GeneOntologyBiologicalProcesspurine ribonucleotide transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

6.20e-0740855GO:0015868
GeneOntologyBiologicalProcessadenine nucleotide transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

7.96e-0742855GO:0051503
GeneOntologyBiologicalProcesspurine nucleotide transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

1.01e-0644855GO:0015865
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-8 ERVK-7 ERVK-10 REV3L

1.57e-0648855GO:0000731
GeneOntologyBiologicalProcessnucleotide transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

1.93e-0650855GO:0006862
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

DOCK2 DHX36 RIPOR2 ATP8A1 RUVBL1 PTPRF SLC25A4 SLC25A5 MARK4 LRRK2 CASP4 PSMC6 SPIRE1 MCRS1 KIF3C MARK2 CUL7 LYN TBX5

2.23e-0613668519GO:0051130
GeneOntologyBiologicalProcessorganophosphate ester transport

SLC25A41 SLC25A42 ATP8A1 SLC25A4 SLC25A5 SLC25A6 ABCA12

4.78e-06162857GO:0015748
GeneOntologyBiologicalProcessnucleobase-containing compound transport

ERVK-6 SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 XPO5 NUP210

8.71e-06249858GO:0015931
GeneOntologyBiologicalProcesscell-cell fusion

DOCK2 ERVK-6 RIPOR2 ERVK-8 ERVK-19

2.67e-0585855GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

DOCK2 ERVK-6 RIPOR2 ERVK-8 ERVK-19

2.67e-0585855GO:0000768
GeneOntologyBiologicalProcessnegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

SLC25A4 SLC25A5 SLC25A6

2.97e-0515853GO:1901029
GeneOntologyBiologicalProcesssyncytium formation

DOCK2 ERVK-6 RIPOR2 ERVK-8 ERVK-19

3.34e-0589855GO:0006949
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1A GABRR1 CACNA1E IBTK SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A PLCB2 LYN UNC80 GABRA4

4.56e-0511158515GO:0034220
GeneOntologyBiologicalProcesscarbohydrate derivative transport

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

4.81e-0596855GO:1901264
GeneOntologyBiologicalProcessorganic anion transport

CACNA1A SLC25A41 SLC25A42 SLC4A8 SLC25A4 SLC25A5 SLC25A6 SLC22A1 CPT1B LYN

5.05e-055158510GO:0015711
GeneOntologyBiologicalProcessregulation of regulated secretory pathway

CACNA1A CACNA1E SLC4A8 LRRK2 HMOX1 LYN

6.21e-05165856GO:1903305
GeneOntologyBiologicalProcessmitochondrial transmembrane transport

SLC25A41 SLC25A4 SLC25A5 SLC25A6 CPT1B

7.72e-05106855GO:1990542
GeneOntologyBiologicalProcesspositive regulation of cardioblast differentiation

DHX36 TBX5

1.00e-044852GO:0051891
GeneOntologyBiologicalProcessnegative regulation of mitochondrial membrane permeability

SLC25A4 SLC25A5 SLC25A6

1.13e-0423853GO:0035795
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1A CACNA1E IBTK SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A PLCB2 LYN UNC80

1.21e-049428513GO:0098655
GeneOntologyBiologicalProcessregulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

SLC25A4 SLC25A5 SLC25A6

1.28e-0424853GO:1901028
GeneOntologyBiologicalProcessnegative regulation of membrane permeability

SLC25A4 SLC25A5 SLC25A6

1.64e-0426853GO:1905709
GeneOntologyBiologicalProcessregulation of cardioblast differentiation

DHX36 TBX5

1.66e-045852GO:0051890
GeneOntologyBiologicalProcessregulated exocytosis

CACNA1A CACNA1E SLC4A8 ABCA12 LRRK2 HMOX1 LYN

2.00e-04291857GO:0045055
GeneOntologyBiologicalProcessadenine transport

SLC25A4 SLC25A5

2.49e-046852GO:0015853
GeneOntologyBiologicalProcessDNA biosynthetic process

ERVK-6 ERVK-8 MCRS1 ERVK-7 ERVK-10 REV3L

2.84e-04218856GO:0071897
GeneOntologyBiologicalProcessDNA replication

ERVK-6 RUVBL1 ERVK-8 MCRS1 ERVK-7 ERVK-10 REV3L

3.05e-04312857GO:0006260
GeneOntologyBiologicalProcessbehavioral response to pain

CACNA1A CACNA1E SCN3A

3.07e-0432853GO:0048266
GeneOntologyBiologicalProcessmitochondrial outer membrane permeabilization

SLC25A4 SLC25A5 SLC25A6

3.37e-0433853GO:0097345
GeneOntologyBiologicalProcessregulation of organelle organization

DHX36 RIPOR2 RUVBL1 SLC25A4 SLC25A5 SLC25A6 MARK4 LRRK2 CUL9 SPIRE1 MCRS1 MARK2 CUL7 GBA2 ZFY

3.53e-0413428515GO:0033043
GeneOntologyBiologicalProcessmicrotubule-based process

CACNA1E KIF6 RIPOR2 IFT52 YIF1B DNAH10 MARK4 CUL9 SPIRE1 KIF3C MARK2 CUL7 GBA2

3.76e-0410588513GO:0007017
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ERVK-8 ERVK-7 ERVK-10

3.85e-0483854GO:0006278
GeneOntologyBiologicalProcessgamma-aminobutyric acid signaling pathway

CACNA1A GABRR1 GABRA4

4.02e-0435853GO:0007214
GeneOntologyBiologicalProcessregulation of exocytosis

CACNA1A CACNA1E SLC4A8 LRRK2 HMOX1 LYN

4.05e-04233856GO:0017157
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1A GABRR1 CACNA1E IBTK SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A PLCB2 LYN UNC80 GABRA4

4.53e-0413748515GO:0006811
GeneOntologyBiologicalProcessregulation of mitochondrion organization

SLC25A4 SLC25A5 SLC25A6 LRRK2 SPIRE1

5.56e-04162855GO:0010821
GeneOntologyBiologicalProcesspositive regulation of mitochondrial membrane permeability involved in apoptotic process

SLC25A4 SLC25A5 SLC25A6

5.98e-0440853GO:1902110
GeneOntologyBiologicalProcessmitochondrial outer membrane permeabilization involved in programmed cell death

SLC25A4 SLC25A5 SLC25A6

6.90e-0442853GO:1902686
GeneOntologyBiologicalProcesspositive regulation of rRNA processing

BUD23 RIOK1

7.39e-0410852GO:2000234
GeneOntologyBiologicalProcesspositive regulation of autophagy

SLC25A4 SLC25A5 UBR4 LRRK2 HMOX1

7.48e-04173855GO:0010508
GeneOntologyBiologicalProcessDNA recombination

ERVK-6 RUVBL1 ERVK-8 MCRS1 ERVK-7 ERVK-10 REV3L

8.14e-04368857GO:0006310
GeneOntologyBiologicalProcesspositive regulation of mitochondrial membrane permeability

SLC25A4 SLC25A5 SLC25A6

8.46e-0445853GO:0035794
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-6 ERVK-8 ERVK-7 ERVK-10 REV3L

8.50e-04178855GO:0006261
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1A CACNA1E IBTK SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC22A1 SCN3A PLCB2 LYN UNC80

8.70e-0411578513GO:0006812
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1A GABRR1 CACNA1E IBTK SLC4A8 SLC25A4 SLC25A5 TRPM3 SCN3A PLCB2 LYN GABRA4

9.17e-0410178512GO:0098660
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

DHX36 RIPOR2 PTPRF MARK4 KIF3C MARK2 CUL7 LYN

9.80e-04494858GO:0031346
GeneOntologyBiologicalProcesspurine nucleobase transport

SLC25A4 SLC25A5

1.08e-0312852GO:0006863
GeneOntologyBiologicalProcessacetylcholine transport

CACNA1A SLC22A1

1.08e-0312852GO:0015870
GeneOntologyBiologicalProcessregulation of mitochondrial membrane permeability involved in apoptotic process

SLC25A4 SLC25A5 SLC25A6

1.09e-0349853GO:1902108
GeneOntologyBiologicalProcesspositive regulation of membrane permeability

SLC25A4 SLC25A5 SLC25A6

1.15e-0350853GO:1905710
GeneOntologyCellularComponentmitochondrial membrane

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 ABCA12 GLUD1 LRRK2 SPIRE1 HADHA HMOX1 CPT1B LYN

3.98e-058668413GO:0031966
GeneOntologyCellularComponentmitochondrial envelope

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 ABCA12 GLUD1 LRRK2 SPIRE1 HADHA HMOX1 CPT1B LYN

6.75e-059128413GO:0005740
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1A DHX36 CACNA1E IFT52 SLC4A8 PTPRF SCN3A MARK4 LRRK2 CASP4 MCRS1 KIF3C MARK2 ADCY2 GABRA4

1.01e-0412288415GO:0036477
GeneOntologyCellularComponentmitochondrial inner membrane

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 ABCA12 GLUD1 LRRK2 HADHA LYN

1.31e-045938410GO:0005743
GeneOntologyCellularComponentorganelle inner membrane

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 ABCA12 GLUD1 LRRK2 HADHA LYN

2.81e-046528410GO:0019866
GeneOntologyCellularComponentmitochondrial permeability transition pore complex

SLC25A4 SLC25A5

3.31e-047842GO:0005757
GeneOntologyCellularComponentorganelle envelope

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6 ABCA12 NUP210 GLUD1 LRRK2 INTS1 SPIRE1 HADHA HMOX1 CPT1B LYN

5.44e-0414358415GO:0031967
GeneOntologyCellularComponentdendrite

CACNA1A DHX36 IFT52 SLC4A8 MARK4 LRRK2 MCRS1 KIF3C MARK2 ADCY2 GABRA4

6.29e-048588411GO:0030425
GeneOntologyCellularComponentdendritic tree

CACNA1A DHX36 IFT52 SLC4A8 MARK4 LRRK2 MCRS1 KIF3C MARK2 ADCY2 GABRA4

6.42e-048608411GO:0097447
DomainMit_carrier

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

2.34e-0732805IPR002067
DomainSOLCAR

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

3.10e-0653805PS50920
Domain-

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

3.10e-06538051.50.40.10
DomainMitochondrial_sb/sol_carrier

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

3.10e-0653805IPR018108
DomainMito_carr

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

3.10e-0653805PF00153
DomainMt_carrier_dom

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

3.10e-0653805IPR023395
DomainAden_trnslctor

SLC25A41 SLC25A4 SLC25A5 SLC25A6

5.91e-0628804IPR002113
DomainMit_uncoupling

SLC25A4 SLC25A5 SLC25A6

1.62e-0512803IPR002030
DomainAAA+_ATPase

MMAA RUVBL1 DNAH10 ABCA12 PSMC6 SNRNP200

3.56e-05144806IPR003593
DomainAAA

MMAA RUVBL1 DNAH10 ABCA12 PSMC6 SNRNP200

3.56e-05144806SM00382
DomainCul7

CUL9 CUL7

5.42e-053802PF11515
DomainCPH_domain

CUL9 CUL7

5.42e-053802IPR021097
DomainARM-type_fold

DOCK2 RIPOR2 XPO5 UBR4 LRRK2 INTS1 CUL9 CUL7

1.01e-04339808IPR016024
DomainMARK/par1

MARK4 MARK2

1.08e-044802IPR033624
DomainKA1_dom

MARK4 MARK2

1.80e-045802IPR001772
DomainKA1

MARK4 MARK2

1.80e-045802PF02149
DomainKA1

MARK4 MARK2

1.80e-045802PS50032
Domain-

MARK4 MARK2

1.80e-0458023.30.310.80
DomainVDCC_a1su_IQ

CACNA1A CACNA1E

3.75e-047802IPR014873
DomainAPC_su10/DOC_dom

CUL9 CUL7

3.75e-047802IPR004939
DomainGPHH

CACNA1A CACNA1E

3.75e-047802PF16905
DomainDOC

CUL9 CUL7

3.75e-047802PS51284
DomainKA1/Ssp2_C

MARK4 MARK2

3.75e-047802IPR028375
DomainGPHH_dom

CACNA1A CACNA1E

3.75e-047802IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1E

3.75e-047802SM01062
DomainCa_chan_IQ

CACNA1A CACNA1E

3.75e-047802PF08763
DomainAPC10

CUL9 CUL7

3.75e-047802SM01337
DomainANAPC10

CUL9 CUL7

3.75e-047802PF03256
DomainCullin_Nedd8

CUL9 CUL7

4.99e-048802PF10557
DomainCullin_Nedd8

CUL9 CUL7

4.99e-048802SM00884
DomainCullin_neddylation_domain

CUL9 CUL7

4.99e-048802IPR019559
DomainCullin_homology

CUL9 CUL7

6.40e-049802IPR016158
DomainCullin

CUL9 CUL7

7.97e-0410802PF00888
DomainCULLIN_2

CUL9 CUL7

7.97e-0410802PS50069
DomainVDCCAlpha1

CACNA1A CACNA1E

7.97e-0410802IPR002077
DomainCullin_N

CUL9 CUL7

7.97e-0410802IPR001373
DomainCULLIN_1

CUL9 CUL7

7.97e-0410802PS01256
DomainBTB-kelch_protein

KLHL9 KLHL36 KLHL32

8.25e-0443803IPR017096
DomainP-loop_NTPase

MMAA DHX36 KIF6 RUVBL1 DNAH10 MYO7A ABCA12 LRRK2 PSMC6 KIF3C SNRNP200

9.47e-048488011IPR027417
DomainARM-like

DOCK2 RIPOR2 XPO5 LRRK2 CUL9 CUL7

1.06e-03270806IPR011989
DomainIon_trans_dom

CACNA1A CACNA1E TRPM3 SCN3A

1.46e-03114804IPR005821
DomainIon_trans

CACNA1A CACNA1E TRPM3 SCN3A

1.46e-03114804PF00520
DomainChannel_four-helix_dom

CACNA1A CACNA1E SCN3A

1.87e-0357803IPR027359
Domain-

CACNA1A CACNA1E SCN3A

1.87e-03578031.20.120.350
DomainKelch

KLHL9 KLHL36 KLHL32

1.97e-0358803SM00612
DomainBACK

KLHL9 KLHL36 KLHL32

2.17e-0360803SM00875
DomainBACK

KLHL9 KLHL36 KLHL32

2.28e-0361803PF07707
DomainBACK

KLHL9 KLHL36 KLHL32

2.28e-0361803IPR011705
DomainSH3

DOCK2 FNBP1 NEBL MYO7A LYN

2.35e-03216805SM00326
DomainSH3

DOCK2 FNBP1 NEBL MYO7A LYN

2.35e-03216805PS50002
DomainBTB

IBTK KLHL9 KLHL36 KLHL32

2.42e-03131804PF00651
DomainSH3_domain

DOCK2 FNBP1 NEBL MYO7A LYN

2.54e-03220805IPR001452
Domain-

RIPOR2 XPO5 LRRK2 CUL9 CUL7

2.65e-032228051.25.10.10
DomainRib_L2_dom2

CUL9 CUL7

2.65e-0318802IPR014722
Domain-

CUL9 CUL7

2.65e-03188022.30.30.30
DomainRCC1

IBTK HERC5

3.27e-0320802PF00415
DomainKelch_1

KLHL9 KLHL36 KLHL32

3.37e-0370803PF01344
DomainKelch_1

KLHL9 KLHL36 KLHL32

3.37e-0370803IPR006652
DomainRCC1_1

IBTK HERC5

3.61e-0321802PS00625
DomainRCC1_2

IBTK HERC5

3.61e-0321802PS00626
DomainRCC1_3

IBTK HERC5

3.61e-0321802PS50012
DomainReg_chr_condens

IBTK HERC5

3.96e-0322802IPR000408
Domain-

IBTK HERC5

3.96e-03228022.130.10.30
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1A CACNA1E SLC25A4 SLC25A5 SLC25A6

7.62e-0823695M47666
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6 PLCB2

1.53e-0618694M47659
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6 PLCB2

2.40e-0620694M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6 PLCB2

2.95e-0621694M47689
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6 PLCB2

3.60e-0622694M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6 PLCB2

3.60e-0622694M47675
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6 PLCB2

4.34e-0623694M47676
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006

SLC25A4 SLC25A5 SLC25A6

1.31e-0510693M47694
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC25A4 SLC25A5 SLC25A6

2.39e-0512693M27728
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1E SLC25A4 SLC25A5 SLC25A6 PLCB2 ADCY2

2.54e-05178697M2890
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

SLC25A4 SLC25A5 SLC25A6 NUP210

3.07e-0537694M1029
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

3.10e-0513693M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

3.10e-0513693M47751
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

3.10e-0513693M47703
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

SLC25A4 SLC25A5 SLC25A6

3.93e-0514693M47692
PathwayREACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS

DOCK2 SLC25A4 SLC25A5 SLC25A6 NUP210 PSMC6

4.26e-05131696M5283
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

4.90e-0515693M47691
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

6.00e-0516693M47695
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1A GABRR1 CACNA1E SLC22A1 PLCB2 ADCY2 GABRA4

7.49e-05211697MM14502
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

8.69e-0518693M47761
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

1.03e-0419693M47677
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.03e-0419693M47760
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC4A8 ATP8A1 SLC25A4 SLC25A5 TRPM3 SLC25A6 ABCA12 SLC22A1 PSMC6 HMOX1 ADCY2 UNC80

2.12e-047366912M27287
PathwayREACTOME_NEURONAL_SYSTEM

CACNA1A GABRR1 CACNA1E PTPRF SLC22A1 PLCB2 ADCY2 GABRA4

2.21e-04335698MM14503
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1A GABRR1 CACNA1E SLC22A1 PLCB2 ADCY2 GABRA4

3.43e-04270697M15514
PathwayPID_IL8_CXCR2_PATHWAY

DOCK2 PLCB2 LYN

6.02e-0434693M210
PathwayREACTOME_NEURONAL_SYSTEM

CACNA1A GABRR1 CACNA1E PTPRF SLC22A1 PLCB2 ADCY2 GABRA4

8.61e-04411698M735
PathwayREACTOME_HIV_INFECTION

DOCK2 SLC25A4 SLC25A5 SLC25A6 NUP210 PSMC6

9.19e-04231696M12469
PathwayBIOCARTA_ETC_PATHWAY

SLC25A4 SLC25A6

1.04e-0310692M15371
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC25A4 SLC25A5 SLC25A6

1.20e-0343693M881
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

1.26e-0311692MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

1.26e-0311692M26913
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1E

1.26e-0311692M47958
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC25A4 SLC25A5

1.26e-0311692MM15471
Pubmed

Expression of leucine-rich repeat kinase 2 (LRRK2) inhibits the processing of uMtCK to induce cell death in a cell culture model system.

SLC25A4 SLC25A5 SLC25A6 LRRK2

1.27e-09787421370995
Pubmed

The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae.

SLC25A4 SLC25A5 SLC25A6

1.51e-08387312450408
Pubmed

DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.

SLC25A4 SLC25A5 SLC25A6

1.51e-0838732541251
Pubmed

Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.

SLC25A4 SLC25A5 SLC25A6

1.51e-0838732829183
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK2 SLC4A8 PER3 TULP4 TRPM3 NUP210 CUL7 GBA2 SNRNP200 UNC80 TBC1D9

4.41e-08493871115368895
Pubmed

Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers.

SLC25A4 SLC25A5 SLC25A6

6.04e-08487333396658
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

6.04e-08487310469592
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19 ERVK-10

6.04e-0848737983737
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-25 ERVK-10

1.40e-079487621542922
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19 ERVK-7

1.51e-07587312629516
Pubmed

The mitochondrial transporter family SLC25: identification, properties and physiopathology.

SLC25A41 SLC25A42 SLC25A4 SLC25A5 SLC25A6

2.28e-075387523266187
Pubmed

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

SLC25A4 SLC25A5 SLC25A6

3.01e-07687310620603
Pubmed

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.

SLC25A4 SLC25A5 SLC25A6 LRRK2

3.74e-072487424725412
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TINAGL1 PTPRF TULP4 MYO7A KLHL36 UBR4 MARK4 INTS1 CUL9 SPIRE1 BCAM REV3L GBA2 TBC1D9

6.15e-071105871435748872
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX36 XPO5 UBR4 NUP210 RCL1 INTS1 CUL9 HADHA CUL7 SNRNP200 HERC5

7.23e-07653871122586326
Pubmed

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.

RUVBL1 SLC25A5 SLC25A6 GLUD1 HADHA

7.45e-076787530669930
Pubmed

TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.

SLC25A4 SLC25A5 SLC25A6

8.39e-07887327641616
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

DHX36 RIOK1 RUVBL1 SLC25A4 SLC25A5 SLC25A6 XPO5 UBR4 GLUD1 RCL1 INTS1 PSMC6 HADHA LYN SNRNP200

8.97e-071318871530463901
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

TINAGL1 DOCK2 ABCA12 NUP210 CUL9 CUL7 HERC5

1.17e-0621487722199357
Pubmed

Genetics of dizziness: cerebellar and vestibular disorders.

CACNA1A MYO7A GBA2

1.26e-06987324275721
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RUVBL1 PTPRF SLC25A5 SLC25A6 APMAP NUP210 GLUD1 INTS1 HADHA MARK2 CUL7 LYN SNRNP200

1.58e-061024871324711643
Pubmed

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.

SLC25A4 SLC25A5 SLC25A6 HADHA CPT1B

2.04e-068287520833797
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SLC25A5 TRPM3 MYO7A SCN3A UBR4 INTS1 HADHA REV3L CPT1B LYN SNRNP200

2.30e-06736871129676528
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DHX36 RIOK1 RUVBL1 DNAH10 SLC25A5 XPO5 APMAP UBR4 NUP210 GLUD1 RCL1 PSMC6 KIF3C HADHA SNRNP200

2.35e-061425871530948266
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

IBTK KLHL9 TULP4 SCN3A UBR4 INTS1

2.47e-0615387610718198
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

DHX36 KLHL9 RUVBL1 SLC25A4 SLC25A5 SLC25A6 APMAP UBR4 NUP210 GLUD1 INTS1 PSMC6 HADHA SNRNP200

2.78e-061257871437317656
Pubmed

Mitochondrial membrane permeabilization by HIV-1 Vpr.

SLC25A4 SLC25A5 SLC25A6

3.27e-061287316120388
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-8 ERVK-19

3.27e-061287314557543
Pubmed

Proteomic analysis of the mouse liver mitochondrial inner membrane.

SLC25A42 SLC25A4 SLC25A5 ABCA12 GLUD1 HADHA

5.37e-0617587612865426
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

DHX36 RUVBL1 SLC25A4 SLC25A5 SLC25A6 XPO5 SCN3A NUP210 PSMC6 PABPC1L HADHA LYN SNRNP200

5.75e-061153871329845934
Pubmed

Role of adenine nucleotide translocator 1 in mtDNA maintenance.

SLC25A4 SLC25A6

6.19e-06287210926541
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

6.19e-06287216381801
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

6.19e-0628729060628
Pubmed

Receptor for motilin identified in the human gastrointestinal system.

MLNR MLN

6.19e-06287210381885
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

6.19e-0628729460924
Pubmed

Changes in the expression of the human adenine nucleotide translocase isoforms condition cellular metabolic/proliferative status.

SLC25A5 SLC25A6

6.19e-06287226842067
Pubmed

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore.

SLC25A4 SLC25A5

6.19e-06287214749836
Pubmed

Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction.

SLC25A4 SLC25A5

6.19e-06287227048932
Pubmed

Apoptotic and anti-proliferative effects of all-trans retinoic acid. Adenine nucleotide translocase sensitizes HeLa cells to all-trans retinoic acid.

SLC25A4 SLC25A6

6.19e-06287216556444
Pubmed

cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes.

SLC25A4 SLC25A6

6.19e-0628722823266
Pubmed

MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway.

MARK4 MARK2

6.19e-06287235192892
Pubmed

Demonstration of a functional motilin receptor in TE671 cells from human cerebellum.

MLNR MLN

6.19e-06287211259768
Pubmed

The motilin pharmacophore in CHO cells expressing the human motilin receptor.

MLNR MLN

6.19e-06287212054506
Pubmed

Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes.

SLC25A4 SLC25A5

6.19e-06287210974536
Pubmed

Identification of peptide ligand-binding domains within the human motilin receptor using photoaffinity labeling.

MLNR MLN

6.19e-06287211461914
Pubmed

A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant progressive external ophthalmoplegia patients with mitochondrial DNA with multiple deletions.

SLC25A4 SLC25A6

6.19e-06287212112115
Pubmed

A novel missense adenine nucleotide translocator-1 gene mutation in a Greek adPEO family.

SLC25A4 SLC25A6

6.19e-06287211756613
Pubmed

The Involvment of Hematopoietic-Specific PLC -β2 in Homing and Engraftment of Hematopoietic Stem/Progenitor Cells.

PLCB2 HMOX1

6.19e-06287227704316
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

DHX36 RIOK1 SLC25A5 SLC25A6 GLUD1 RCL1 HADHA MARK2 SNRNP200 HERC5

7.70e-06678871030209976
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

BUD23 RUVBL1 SLC25A4 SLC25A5 SLC25A6 UBR4 PSMC6 BCAT1 HADHA SNRNP200

1.07e-05704871029955894
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

RUVBL1 XPO5 NUP210 GLUD1 SNRNP200

1.33e-0512087527320910
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

RUVBL1 PTPRF UBR4 CUL9 HADHA CUL7 SNRNP200

1.41e-0531387738270169
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

DHX36 IBTK RUVBL1 XPO5 UBR4 CASP4 PSMC6 SPIRE1 MCRS1 HADHA MARK2 LYN SNRNP200

1.80e-051284871317353931
Pubmed

Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.

CUL9 CUL7

1.85e-05387217229476
Pubmed

Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.

CUL9 CUL7

1.85e-05387215964813
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

1.85e-05387210516026
Pubmed

The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.

CUL9 CUL7

1.85e-05387217298945
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1E

1.85e-05387238996073
Pubmed

A novel p53-binding domain in CUL7.

CUL9 CUL7

1.85e-05387216875676
Pubmed

Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively.

SLC25A4 SLC25A5

1.85e-05387216831128
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1E

1.85e-05387224523520
Pubmed

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.

MARK4 MARK2

1.85e-0538729108484
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

MMAA SLC25A42 SLC25A4 SLC25A5 GLUD1 HADHA CPT1B

2.02e-0533187729199018
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

DHX36 IBTK RUVBL1 SLC25A4 SLC25A6 RCL1 MARK2 CUL7 SNRNP200 HERC5

2.04e-05759871035915203
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

RUVBL1 SLC25A5 SLC25A6 XPO5 PSMC6 HADHA SNRNP200

2.58e-0534487736282215
Pubmed

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.

PTPRF SLC25A4 SLC25A5 UBR4

2.79e-056987426792178
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

CUL9 CUL7 SNRNP200

2.95e-052487333705438
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

RUVBL1 SLC25A5 PSMC6 HADHA SNRNP200

3.19e-0514487535681168
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

RIOK1 KLHL9 RUVBL1 SLC25A5 PSMC6 KIF3C HADHA SNRNP200

3.48e-0549587828581483
Pubmed

Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.

SLC25A4 SLC25A5 SLC25A6 XPO5

3.48e-057387423464991
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1E

3.70e-05487232616470
Pubmed

Rapid evolution of human pseudoautosomal genes and their mouse homologs.

SLC25A4 SLC25A5

3.70e-0548728903724
Pubmed

Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis.

SLC25A4 SLC25A5

3.70e-05487231883789
Pubmed

The interaction between cell adhesion molecule L1, matrix metalloproteinase 14, and adenine nucleotide translocator at the plasma membrane regulates L1-mediated neurite outgrowth of murine cerebellar neurons.

SLC25A4 SLC25A5

3.70e-05487222423112
Pubmed

Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD.

SLC25A4 SLC25A5

3.70e-05487231489369
Pubmed

The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.

SLC25A4 SLC25A5

3.70e-05487231618756
Pubmed

Ikappa b-alpha, the NF-kappa B inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator.

SLC25A4 SLC25A5

3.70e-05487211287411
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1E

3.70e-05487237141091
Pubmed

Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.

RUVBL1 SLC25A5 SLC25A6 GLUD1 SNRNP200

4.00e-0515187518457437
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

RIOK1 RUVBL1 SLC25A5 SLC25A6 MYO7A ABCA12 LRRK2 SNRNP200

4.47e-0551387825798074
Pubmed

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

RUVBL1 SLC25A4 SLC25A5 SLC25A6 GLUD1 HADHA

4.60e-0525687635777956
Pubmed

Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins.

GLUD1 HADHA NMBR

4.73e-052887320736409
Pubmed

Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.

RUVBL1 SLC25A6 GLUD1 PSMC6 HADHA SNRNP200

4.80e-0525887621081666
Pubmed

Ski regulates Hippo and TAZ signaling to suppress breast cancer progression.

SLC25A4 SLC25A5 SLC25A6 HADHA

6.05e-058487425670202
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

RIOK1 RUVBL1 SLC25A5 SLC25A6 APMAP PSMC6

6.05e-0526987630442662
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1E

6.16e-0558728825650
Pubmed

CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.

CUL9 CUL7

6.16e-05587224793696
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

6.16e-05587211401426
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1E

6.16e-05587215451373
Pubmed

PARC and CUL7 form atypical cullin RING ligase complexes.

CUL9 CUL7

6.16e-05587217332328
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1E

6.16e-05587211296258
Pubmed

H+ transport is an integral function of the mitochondrial ADP/ATP carrier.

SLC25A4 SLC25A5

6.16e-05587231341297
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

IBTK RIOK1 RUVBL1 SLC25A5 SLC25A6 GLUD1 PSMC6 HERC5

7.00e-0554787837267103
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNBP1 RIPOR2 XPO5 MARK4 CUL9 KLHL32 ADCY2

7.46e-0540787712693553
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

DHX36 RUVBL1 SLC25A4 SLC25A5 SLC25A6 GLUD1 PSMC6 HADHA SNRNP200

7.59e-0571487928302793
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

RUVBL1 NEBL RAPH1 SLC25A4 SLC25A5 SLC25A6 HADHA MARK2

8.03e-0555887835063084
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

DHX36 IBTK SLC25A4 SLC25A5 SLC25A6 UBR4 GLUD1 RCL1 PSMC6 SPIRE1 HADHA MARK2 CUL7

8.64e-051496871332877691
Pubmed

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.

RUVBL1 SLC25A4 SLC25A5 SLC25A6 HADHA LYN

8.81e-0528887631501420
Pubmed

Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.

MARK4 MARK2

9.22e-05687223666762
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1E

9.22e-05687235324301
InteractionMAP1B interactions

CACNA1A GABRR1 RUVBL1 SLC25A4 SLC25A5 SLC25A6 UBR4 GLUD1 LRRK2 HADHA CUL7 SNRNP200

1.79e-065398212int:MAP1B
InteractionTOP3B interactions

TINAGL1 IBTK RIOK1 PTPRF TULP4 XPO5 MYO7A KLHL36 UBR4 MARK4 INTS1 CUL9 SPIRE1 HADHA BCAM REV3L LYN GBA2 TBC1D9

5.18e-0614708219int:TOP3B
InteractionSIRT4 interactions

SLC25A5 SLC25A6 GLUD1

2.85e-0515823int:SIRT4
InteractionTNPO1 interactions

FNBP1 RUVBL1 UBR4 LRRK2 PSMC6 HADHA CUL7 SNRNP200

3.47e-05306828int:TNPO1
InteractionPAK1 interactions

SLC25A41 RIOK1 RUVBL1 SLC25A4 SLC25A5 SLC25A6 LYN

4.12e-05229827int:PAK1
CytobandYp11.3

SLC25A6 ZFY

4.09e-0416862Yp11.3
Cytoband2p23

KIF3C HADHA

4.63e-04178622p23
Cytoband6p21.1

XPO5 CUL9 CUL7

4.70e-04808636p21.1
Cytoband4q31.21

MMAA TBC1D9

1.09e-03268624q31.21
GeneFamilySolute carriers

SLC25A41 SLC25A42 SLC4A8 SLC25A4 SLC25A5 SLC25A6 SLC22A1

2.59e-04395587752
GeneFamilyCullins

CUL9 CUL7

2.80e-0485821032
GeneFamilyKelch like|BTB domain containing

KLHL9 KLHL36 KLHL32

3.29e-0442583617
GeneFamilyBasic leucine zipper proteins|BTB domain containing

IBTK KLHL9 KLHL36 KLHL32

8.98e-04134584861
GeneFamilyINO80 complex |SRCAP complex

RUVBL1 MCRS1

1.03e-0315582595
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRR1 GABRA4

1.67e-0319582563
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1E

3.13e-0326582253
CoexpressionGSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN

BUD23 KLHL9 MYO7A PLCB2 HADHA REV3L TBC1D9

2.92e-06200817M6621
CoexpressionXU_GH1_AUTOCRINE_TARGETS_UP

DOCK2 SLC25A4 SLC25A6 ABCA12 HERC5 ZFY GABRA4

3.02e-06201817M10664
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CACNA1A FNBP1 CACNA1E RIPOR2 SLC4A8 ATP8A1 RAPH1 TULP4 MYO7A SCN3A LRRK2 KIF3C REV3L TBC1D9

6.79e-0611068114M39071
CoexpressionGSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_UP

PTPRF NEBL UBR4 RCL1 SERPINB2 BCAT1

2.61e-05188816M6167
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 LRRK2 BCAT1 SPIRE1 PLCB2 LYN

1.52e-06195816ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 FNBP1 RIPOR2 BCAT1 PLCB2 LYN

1.52e-061958167b6c69df943842b566a596e30bb50dbe80dccc83
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A PTPRF TULP4 REV3L KLHL32 UNC80

1.52e-061958167796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Monocytes,_Macrophages|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOCK2 RIPOR2 SERPINB2 CASP4 HMOX1 LYN

1.66e-061988167490b30462d03b5edee3bcacdef9483dd15821b5
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOCK2 RIPOR2 SERPINB2 CASP4 HMOX1 LYN

1.66e-061988164f86ff6ba8cbe987e7541fca4f3ae8d0e434677d
ToppCellLPS_only-Epithelial_alveolar|LPS_only / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF LRRK2 BCAT1 HMOX1 BCAM

1.66e-06198816655df75b9692d815c7f6910275e1f684ac63bf62
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF LRRK2 BCAT1 HMOX1 BCAM

1.66e-0619881682bcd44f8744e7e8477fbfd871a52f3d1a8b3adc
ToppCelldistal-2-Hematologic-Intermediate_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DOCK2 RIPOR2 LRRK2 BCAT1 HMOX1 LYN

1.71e-061998165e209df67cfe8ac7437cc363f1c5c3166bfae1af
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATP8A1 PTPRF MARK4 KLHL32 SNRNP200

5.56e-061398157c02caed5b9baf233bd6fb9a453708b3e157c790
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1E RIPOR2 BCAT1 PLCB2 LYN

8.58e-06152815b750302d442160a1007659c2386ac90282bf95d2
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A41 NEBL DNAH10 ADCY2 TBC1D9

9.14e-061548151e32969bee810adaf2d560f0824a16227df513d8
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RUVBL1 KLHL36 SCN3A UBR4 PABPC1L

9.74e-06156815895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ATP8A1 DNAH10 SPIRE1 KLHL32

1.20e-051638158dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ATP8A1 DNAH10 SPIRE1 KLHL32

1.20e-05163815fd243ca223079033be480a24817a399f281fa4d4
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A PER3 SLC25A5 TRPM3 MARK2

1.24e-05164815b895674ed2df87db8fbfb30b7e31620945588491
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN3A SPIRE1 TBC1D9 TBX5

1.43e-051698150332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A41 NEBL DNAH10 CPT1B ADCY2

1.43e-0516981530141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 SLC4A8 NEBL PLCB2 ADCY2

1.47e-0517081517bd7fd25a2657cb536ad47e294332920f759e95
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK2 RIPOR2 SCN3A NUP210 LYN

1.79e-05177815653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 ATP8A1 RAPH1 TRPM3 TBX5

1.89e-0517981514fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1E RIPOR2 LRRK2 LYN TBC1D9

1.94e-05180815eedb6d89680f968167afb1dcd132c9de9096b50f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN3A SPIRE1 TBC1D9 TBX5

1.94e-05180815788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

1.99e-05181815b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

2.16e-0518481542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A6 SCN3A SPIRE1 BCAM TBC1D9

2.16e-051848159690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

2.16e-05184815cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AHI1-DT RIPOR2 NEBL LRRK2 BCAM

2.16e-05184815da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ATP8A1 DNAH10 KLHL36 SCN3A

2.21e-05185815bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 FNBP1 RIPOR2 NUP210 LYN

2.21e-05185815e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

2.27e-051868153aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AHI1-DT RIPOR2 NEBL TRPM3 LRRK2

2.27e-05186815f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL SCN3A SPIRE1 BCAM TBC1D9

2.27e-05186815b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1A SCN3A KLHL32 ADCY2 UNC80

2.27e-05186815b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

2.33e-0518781558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

2.33e-05187815ff26a533d310126521efe1d05cf8b9d32e524550
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL SLC22A1 CPT1B KLHL32 TBX5

2.39e-0518881590dc0e15798d0b984518ad58c7e416e30aff687a
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL SLC22A1 CPT1B KLHL32 TBX5

2.39e-05188815f63dfd076ced81013918363282ae25cbbd8948ae
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL SLC22A1 CPT1B KLHL32 TBX5

2.39e-051888150554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCellfacs-Heart-LA/RA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL SLC22A1 CPT1B KLHL32 TBX5

2.45e-05189815a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 MYO7A LRRK2 HMOX1 LYN

2.45e-05189815b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCellfacs-Heart-LA/RA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL SLC22A1 CPT1B KLHL32 TBX5

2.45e-05189815efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 LRRK2 BCAT1 SPIRE1 LYN

2.58e-051918153b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 RIPOR2 LRRK2 PLCB2 LYN

2.58e-0519181547a2afc4102199b4bc76bd01b2967c8016186462
ToppCellmoderate-Lymphoid-B_cell|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RIPOR2 SCN3A LRRK2 LYN TBC1D9

2.65e-05192815ae3727503c3b9f4695e565fd3161cc33b898f349
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

FNBP1 RIPOR2 LRRK2 LYN TBC1D9

2.71e-051938157ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRF TRPM3 SCN3A SPIRE1 TBC1D9

2.78e-05194815be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellcontrol-Lymphoid-B_cell|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RIPOR2 LRRK2 HMOX1 LYN TBC1D9

2.78e-05194815a5284adca931a78b1c4592925c4860853ebd24f1
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK2 FNBP1 MYO7A BCAT1 HMOX1

2.78e-05194815663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCellControl-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

ATP8A1 SLC25A5 LRRK2 SPIRE1 LYN

2.78e-05194815a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCellcellseq-Immune-Immune_Myeloid-pMON-pMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOCK2 RIPOR2 PLCB2 HMOX1 LYN

2.85e-051958152cb435dae2691e1250e26e59f9b8fb652a0c383e
ToppCellcellseq-Immune-Immune_Myeloid-pMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOCK2 RIPOR2 PLCB2 HMOX1 LYN

2.85e-05195815217908cb53016a6cb51f1bc3fc752c8df650df71
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A PTPRF REV3L KLHL32 UNC80

2.85e-051958153e519cffa6144a62b06124642a14c9ff39b76554
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

AHI1-DT PTPRF NEBL DNAH10 KLHL32

2.92e-0519681587d9881cfec461a5d89b688a83749b618c519485
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

FNBP1 NUP210 PLCB2 HADHA TBC1D9

2.92e-0519681509d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIF6 ATP8A1 PTPRF BCAT1 BCAM

2.99e-05197815b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 RIPOR2 PLCB2 HMOX1 LYN

2.99e-05197815e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RIPOR2 LRRK2 SERPINB2 CASP4 LYN

2.99e-051978154d3670456655248250d156f92de01df4aa481733
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 FNBP1 RIPOR2 PLCB2 LYN

2.99e-0519781561ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell3'_v3-GI_small-bowel-Myeloid_Monocytic|GI_small-bowel / Manually curated celltypes from each tissue

RAPH1 LRRK2 SERPINB2 HMOX1 LYN

2.99e-05197815dcf0009057576a7db9065e644a3919d6de2ac8e6
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 RIPOR2 PLCB2 HMOX1 LYN

3.07e-05198815ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF LRRK2 BCAT1 HMOX1

3.07e-05198815d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF LRRK2 BCAT1 HMOX1

3.07e-05198815c4e7512f0e1d115f2be8acae6048eda8b6b640b2
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF LRRK2 BCAT1 BCAM

3.07e-0519881553e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TINAGL1 ATP8A1 PTPRF BCAT1 BCAM

3.07e-05198815f006d68e6c51923be7772eea118546a5762e8a5e
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF LRRK2 BCAT1 HMOX1

3.07e-05198815aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KIF6 IFT52 SLC4A8 DNAH10 ADCY2

3.14e-0519981515f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 RIPOR2 PLCB2 HMOX1 LYN

3.14e-051998150a9783808528bc4c6d797d849a9177330c8fb867
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

3.22e-052008152dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellmild-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RAPH1 BCAT1 PLCB2 HMOX1 LYN

3.22e-05200815334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ATP8A1 PTPRF TRPM3 BCAT1 BCAM

3.22e-052008158683445ad5b70748c4a1f12eb77d47623085147e
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GABRR1 ATP8A1 LRRK2 BCAT1

8.51e-051278145b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

YIF1B PER3 RCL1 INTS1

1.35e-0414381457ee1830d96d73d92b5f83b028592a5d952c6013
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC4A8 SLC25A4 DNAH10 KLHL32

1.46e-04146814cffa91d76606f74553d81150adbb23b003746316
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 RIPOR2 SLC25A5 PLCB2

1.58e-04149814a6e192bf9bcf3b219e618c465bc451f7c86f49f1
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

B3GNT4 DNAH10 PLCB2 TBC1D9

1.70e-041528145ce8920aedd39a4daf7082153b5e213707c14227
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SLC4A8 SLC25A4 DNAH10 LYN

1.75e-04153814e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DNAH10 SPIRE1 KLHL32

1.93e-04157814ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellCOPD-Epithelial-PNEC|COPD / Disease state, Lineage and Cell class

NEBL SCN3A BCAM UNC80

2.02e-041598146018124980c55190928409f3bf41d846a118954a
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 ADCY2 UNC80

2.07e-04160814c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 ADCY2 UNC80

2.07e-0416081425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND03-Immune-Immune_Myeloid-DC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNBP1 SLC4A8 TKTL1 TBC1D9

2.12e-04161814f50e91f8363f20bb7c565aaca4d4961d3fe4b5b5
ToppCellE18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|E18.5-samps / Age Group, Lineage, Cell class and subclass

DOCK2 MYO7A PLCB2 TBC1D9

2.17e-0416281460d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCellE18.5-samps-Myeloid|E18.5-samps / Age Group, Lineage, Cell class and subclass

DOCK2 MYO7A PLCB2 TBC1D9

2.17e-0416281418e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCellE18.5-samps-Myeloid-Macrophage|E18.5-samps / Age Group, Lineage, Cell class and subclass

DOCK2 MYO7A PLCB2 TBC1D9

2.17e-041628140970e4eda60e3f015335e2726e6d565fb2f43372
ToppCellPND01-03-samps-Myeloid-Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DOCK2 PLCB2 HMOX1 TBC1D9

2.28e-0416481449733a9d3d95f05056b5b01916060ff20a8de3cf
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 FNBP1 LYN TBC1D9

2.28e-04164814b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A TRPM3 SCN3A CPT1B

2.33e-041658144b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

AHI1-DT ATP8A1 KLHL32 ADCY2

2.33e-041658140c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

AHI1-DT ATP8A1 KLHL32 ADCY2

2.33e-0416581482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A TULP4 REV3L SNRNP200

2.38e-0416681413027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A TULP4 REV3L SNRNP200

2.38e-04166814b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A41 NEBL DNAH10 ADCY2

2.44e-04167814cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

DOCK2 FNBP1 RIPOR2 LYN

2.49e-04168814a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

RIPOR2 SCN3A LYN TBC1D9

2.49e-041688148e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

RIPOR2 SCN3A LYN TBC1D9

2.49e-041688145535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A CACNA1E ADCY2 UNC80

2.55e-04169814b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 ABCA12 SCN3A UNC80

2.55e-0416981412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 RIPOR2 NUP210 LYN

2.61e-04170814a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCelldroplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP4 LYN TBC1D9 GABRA4

2.61e-0417081429deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCelldroplet-Thymus-nan-21m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP4 LYN TBC1D9 GABRA4

2.61e-04170814dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
Drugoleoylcarnitine

SLC25A4 SLC25A5 SLC25A6 GLUD1 CPT1B

2.27e-0916825CID006441392
DrugClodronate

SLC25A4 SLC25A5 SLC25A6

4.50e-083823DB00720
DrugAC1L193Y

SLC25A4 SLC25A5 SLC25A6 GLUD1 HADHA CPT1B

1.26e-0765826CID000000380
Drugdehydroabietylamine

SLC25A4 SLC25A5 SLC25A6

1.80e-074823ctd:C000600819
Drugbeta-hydroxypalmitoyl-CoA

SLC25A4 SLC25A5 SLC25A6 HADHA

3.59e-0717824CID000440600
DrugOxyphenbutazone [129-20-4]; Up 200; 12.4uM; HL60; HT_HG-U133A

B3GNT4 PER3 NEBL MYO7A KLHL36 HMOX1 CUL7 SNRNP200

5.84e-071988286160_UP
Drugclosantel

SLC25A4 SLC25A5 SLC25A6

1.56e-067823ctd:C023342
Drugn-propionyl-CoA

MMAA SLC25A4 SLC25A5 SLC25A6 GLUD1 HADHA CPT1B

2.32e-06166827CID000001033
Druggabapentin

CACNA1A GABRR1 CACNA1E SCN3A GLUD1 BCAT1 GABRA4

2.61e-06169827CID000003446
DrugAC1LCVTP

MMAA NEBL SLC25A4 MLN HMOX1 BCAM

4.33e-06118826CID000656983
DrugAC1L4X2K

SLC25A4 SLC25A5 SLC25A6

5.31e-0610823CID000193824
DrugPHA-00851261E [724719-49-7]; Down 200; 1uM; MCF7; HT_HG-U133A

B3GNT4 ABCA12 MARK4 KIF3C HMOX1 LYN HERC5

6.93e-061968273857_DN
DrugICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A

ATP8A1 TRPM3 MLN PLCB2 LYN ADCY2 TBX5

7.17e-061978275565_UP
DrugME-34

MLNR MLN

1.28e-052822CID000084012
Drugracephenicol

MMAA SLC25A4 SLC25A5 SLC25A6

1.29e-0540824CID000005433
Drugnickel

CACNA1A CACNA1E TRPM3 PLCB2 HMOX1 BCAM REV3L CPT1B GBA2 ADCY2

2.89e-055528210CID000000934
Drugcarbachol

CACNA1A CACNA1E TRPM3 MLNR MLN PLCB2 MARK2 NMBR CPT1B LYN ADCY2

3.53e-056888211CID000002551
DrugAC1L1D9R

CACNA1A CACNA1E SLC25A4 SLC25A5 SLC25A6

3.56e-05103825CID000002254
Drugcarboxyatractyloside

SLC25A4 SLC25A5

3.84e-053822ctd:C003853
Drugsevoflurane

GABRR1 PLCB2 HMOX1 CPT1B GABRA4

3.90e-05105825CID000005206
DrugPtpc

SLC25A4 SLC25A5 SLC25A6 CASP4

4.63e-0555824CID003036276
Drugagaric acid

SLC25A4 SLC25A5 SLC25A6

4.91e-0520823CID000012629
Drugphenylsuccinate

SLC25A4 SLC25A5 SLC25A6

5.71e-0521823CID000095459
DrugFluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A

NEBL TRPM3 UBR4 MLN MARK2 CPT1B

6.46e-051908264314_UP
Drugverapamil

CACNA1A CACNA1E ABCA12 MLNR SLC22A1 SCN3A MLN ADCY2 TBC1D9

6.70e-05490829CID000002520
DrugAzacyclonol [115-46-8]; Up 200; 15uM; MCF7; HT_HG-U133A

B3GNT4 MYO7A CASP4 HMOX1 CUL7 HERC5

7.24e-051948265398_UP
DrugAC 110

CACNA1A CACNA1E

7.65e-054822CID000022860
Drug0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A

YIF1B PER3 NUP210 HMOX1 BCAM CUL7

7.67e-051968263633_DN
DrugSulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A

NEBL MARK4 MARK2 LYN TBC1D9 RNF170

7.89e-051978265507_DN
DrugFurazolidone [67-45-8]; Down 200; 17.8uM; HL60; HT_HG-U133A

CACNA1A KLHL9 NEBL CASP4 KIF3C GABRA4

7.89e-051978263019_DN
DrugCrotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A

B3GNT4 MARK4 INTS1 CUL9 CUL7 ADCY2

7.89e-051978263388_UP
DrugAzaperone [1649-18-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A

TINAGL1 SLC22A1 CASP4 CUL7 SNRNP200 HERC5

7.89e-051978263573_UP
DrugLY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A

NEBL ABCA12 NUP210 MARK4 CUL9 CPT1B

8.11e-051988266976_UP
DrugSulfanilamide [63-74-1]; Down 200; 23.2uM; MCF7; HT_HG-U133A

KLHL36 MARK4 CUL9 KIF3C HMOX1 CUL7

8.34e-051998266810_DN
DrugPHA-00846566E [724718-26-7]; Up 200; 10uM; MCF7; HT_HG-U133A

B3GNT4 NEBL HMOX1 MARK2 CUL7 CPT1B

8.34e-051998267081_UP
DrugDipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A

NEBL TRPM3 SLC22A1 MLN BCAM TBC1D9

8.34e-051998263754_UP
DrugLaudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; HL60; HG-U133A

CACNA1A PTPRF MARK4 INTS1 PLCB2 RNF170

8.57e-052008261741_UP
DrugIpratropium bromide [22254-24-6]; Down 200; 9.8uM; PC3; HT_HG-U133A

NUP210 RCL1 MARK4 INTS1 KIF3C BCAM

8.57e-052008265823_DN
DrugLY294002; Up 200; 10uM; HL60; HG-U133A

CACNA1A NEBL CUL9 BCAM MARK2 TBX5

8.57e-05200826361_UP
Drugadenine

CACNA1E SLC25A41 SLC25A4 SLC25A5 TRPM3 SLC25A6 GLUD1 REV3L ADCY2

9.09e-05510829CID000000190
Drugmethionine hydroxy analog

ERVK-6 MLNR MLN

1.10e-0426823CID000011427
Drug8-azidoethidium

CACNA1A HMOX1

1.27e-045822CID002762649
DrugEM574

MLNR MLN

1.27e-045822CID000084019
DrugAC1L1AH5

SLC25A4 SLC25A5 SLC25A6 GLUD1 HADHA CPT1B

1.27e-04215826CID000000986
Drugcaffeic acid phenethyl ester

CACNA1A KIF6 PER3 DNAH10 SERPINB2 HMOX1 ADCY2

1.31e-04311827ctd:C055494
Drugpyruvic acid

SLC25A4 SLC25A5 SLC25A6 GLUD1 BCAT1 HMOX1 CPT1B ADCY2

1.45e-04424828CID000001060
Drugtetradotoxin

CACNA1A GABRR1 CACNA1E MLNR SCN3A MLN CPT1B GABRA4

1.55e-04428828CID000020382
DrugDexrazoxane

SLC25A42 SLC25A5 CASP4 HADHA HMOX1

1.69e-04143825ctd:D064730
DrugAC1NDLJ6

MCRS1 TKTL1 NMBR

1.70e-0430823CID004627775
DrugHCOH (hydroxymethylene)

SLC25A4 SLC25A5 SLC25A6

1.88e-0431823CID006432217
DrugAC1L432Q

MLNR MLN

1.90e-046822CID000177964
Drug3,4-dihydroquinazoline

CACNA1A CACNA1E

1.90e-046822CID000583065
DrugBongkrekic Acid

SLC25A4 SLC25A5

1.90e-046822ctd:D001865
DrugAC1MIWSL

MLNR MLN

1.90e-046822CID003081371
Drugalpha-sialylcholesterol

CACNA1A CACNA1E

1.90e-046822CID000133976
Diseaseautosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6

7.37e-084793DOID:0111517 (implicated_via_orthology)
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1E RNF170

6.41e-077793DOID:0050951 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA1A CACNA1E SLC25A4 SLC25A5 SLC25A6 SCN3A

5.16e-06163796DOID:1826 (implicated_via_orthology)
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1E

2.12e-053792DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1E

4.23e-054792DOID:6364 (implicated_via_orthology)
Diseasevisual impairment and progressive phthisis bulbi (implicated_via_orthology)

MARK4 MARK2

4.23e-054792DOID:0070356 (implicated_via_orthology)
Diseasehypertrophic cardiomyopathy (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6

6.42e-0529793DOID:11984 (implicated_via_orthology)
Diseasemitochondrial metabolism disease (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6

1.14e-0435793DOID:700 (implicated_via_orthology)
Diseaseargininate measurement

TINAGL1 SLC22A1

1.96e-048792EFO_0800055
Diseaseplatelet measurement

YIF1B PTPRF TRPM3 RCL1 MARK4 LRRK2

2.04e-04315796EFO_0005036
DiseaseMitochondrial Myopathies

SLC25A42 SLC25A4

3.83e-0411792C0162670
Diseasemeningitis

CACNA1E RAPH1

3.83e-0411792MONDO_0021108
Diseasehyperinsulinism (is_implicated_in)

PTPRF GLUD1

4.59e-0412792DOID:2018 (is_implicated_in)
DiseaseErythrocyte Mean Corpuscular Hemoglobin Test

SLC25A4 HADHA

5.42e-0413792C0369183
DiseaseFinding of Mean Corpuscular Hemoglobin

SLC25A4 HADHA

5.42e-0413792C1261502
Diseasehepatic encephalopathy (biomarker_via_orthology)

GLUD1 HMOX1

7.27e-0415792DOID:13413 (biomarker_via_orthology)
DiseaseTremor, Rubral

CACNA1A GABRA4

8.29e-0416792C0750940
DiseaseAtaxia, Appendicular

CACNA1A GABRA4

8.29e-0416792C0750937
DiseaseAtaxia, Motor

CACNA1A GABRA4

8.29e-0416792C0278161
DiseaseAbnormal coordination

CACNA1A GABRA4

8.29e-0416792C0520966
Diseaseidiopathic scoliosis (implicated_via_orthology)

KIF6 DNAH10

8.29e-0416792DOID:0060250 (implicated_via_orthology)
DiseaseAtaxia, Truncal

CACNA1A GABRA4

8.29e-0416792C0427190
DiseaseAtaxia, Sensory

CACNA1A GABRA4

8.29e-0416792C0240991
DiseaseParoxysmal atrial fibrillation

NEBL DNAH10 KIF3C TBX5

8.30e-04156794C0235480
Diseasefamilial atrial fibrillation

NEBL DNAH10 KIF3C TBX5

8.30e-04156794C3468561
DiseasePersistent atrial fibrillation

NEBL DNAH10 KIF3C TBX5

8.30e-04156794C2585653
DiseaseAtrial Fibrillation

NEBL DNAH10 KIF3C TBX5

9.12e-04160794C0004238
Diseasewhite matter lesion progression measurement

DOCK2 CACNA1E SLC4A8

9.26e-0471793EFO_0007746
Diseasetriacylglycerol 56:3 measurement

MLN BCAT1

1.05e-0318792EFO_0010430
Diseasearachidonic acid measurement

CACNA1A FNBP1

2.04e-0325792EFO_0006808
DiseaseAtaxia

CACNA1A GABRA4

2.04e-0325792C0004134
DiseaseEndogenous Hyperinsulinism

GLUD1 HMOX1

2.21e-0326792C1257963
DiseaseExogenous Hyperinsulinism

GLUD1 HMOX1

2.21e-0326792C1257964
DiseaseCompensatory Hyperinsulinemia

GLUD1 HMOX1

2.21e-0326792C1257965
Diseaseamino acid measurement

PER3 ABCA12 SLC22A1 GLUD1 MARK4 KIF3C BCAM

2.27e-03678797EFO_0005134
Diseaseacute kidney failure (implicated_via_orthology)

SLC22A1 HMOX1

2.38e-0327792DOID:3021 (implicated_via_orthology)
DiseaseHyperinsulinism

GLUD1 HMOX1

2.56e-0328792C0020459

Protein segments in the cluster

PeptideGeneStartEntry
SMAQRARTMALYNPI

CACNA1A

51

O00555
TNERFPLRMSRRGMV

BUD23

231

O43709
VVSYPFDTVRRRMMM

SLC25A6

226

P12236
MVSGMSLRPRVNYLQ

ERVK-19

196

O71037
MVSGMSLRPRVNYLQ

ERVK-8

196

Q902F8
NMDRMYRSAVRATLP

BCAT1

116

P54687
PSRSNRMEMSIFYVV

CACNA1E

1391

Q15878
KAQMPTIERLSMTRY

CASP4

356

P49662
RSVPLTQAMYRSNRM

ABCA12

701

Q86UK0
LTSYPFDTVRRRMMM

SLC25A5

226

P05141
TTMARIRRVYVSGLM

APMAP

276

Q9HDC9
SAPMMYSRRGVRRTA

AHI1-DT

71

P0C7V0
MPTMRRTVSEIRSRA

ATP8A1

1

Q9Y2Q0
IRGMAYSVRVSPQMA

RCL1

191

Q9Y2P8
SKARMESMNRPYTSL

RAPH1

591

Q70E73
IMRMRTGTQMPIYVT

NUP210

1176

Q8TEM1
MMEGSRQTRVSRPYK

KLHL36

1

Q8N4N3
RYRAIVNPMDMQTSG

NMBR

141

P28336
EMAPYMKRLSRGQTV

INTS1

2046

Q8N201
FYRKMIPAMDRRVIT

IBTK

926

Q9P2D0
RPISQYARVAMAMGS

KIF3C

686

O14782
RMIRQTPERILMTYQ

PER3

1106

P56645
LYVRDTLQPGMRVRM

CUL7

371

Q14999
PYRNSMMTSVLRDSL

KIF6

296

Q6ZMV9
YMQPVMQSDRTAIRS

KLHL9

281

Q9P2J3
ASTLARMVIRYQMKS

LRRK2

836

Q5S007
RMTELSRDMNAYIRP

MMAA

196

Q8IVH4
LFRIMRNGTILYTMR

GABRA4

151

P48169
LYTMRLTISAECPMR

GABRA4

161

P48169
QYMQRLSTMRTLSNP

PABPC1L

381

Q4VXU2
MVSGMSLRPRVNYLQ

ERVK-7

956

P63135
RKRRTTEMMPVYLDL

HERC5

431

Q9UII4
AKMRASVRMTRYLES

ADCY2

486

Q08462
PQRKSQRSSYVSMRI

GABRR1

436

P24046
MMLPYTATLSKRNRE

IFT52

261

Q9Y366
GRPRSMLRSYRQMSI

DOCK2

1631

Q92608
YVMSRATVRRLQAIM

B3GNT4

281

Q9C0J1
LTRRRYLMSGVMAPV

GBA2

571

Q9HCG7
MVSGMSLRPRVNYLQ

ERVK-25

196

P61570
MVSGMSLRPRVNYLQ

ERVK-6

196

Q69384
ERRIVRMGESMKTYA

FNBP1

221

Q96RU3
AYTMERSARQIMRTA

GLUD1

511

P00367
RRRYSASTVDVIEMM

DHX36

451

Q9H2U1
GRMVRYLMRSREITL

MCRS1

351

Q96EZ8
PRRTELMVSMGYTRE

MARK2

326

Q7KZI7
LPPSMMTRRNTYVCT

MARK4

501

Q96L34
DVMTALSQGYRMPRV

LYN

451

P07948
YTTRCLAPMMSEVIR

HADHA

546

P40939
LYRSRMNSLEMTPAV

HMOX1

181

P09601
PTTRTILMMLLNRYS

CUL9

911

Q8IWT3
SKMVPAYRMQSPRAL

CXorf1

86

O96002
MYRMKRSQVRTPIRR

LINC01545

1

Q5VT33
MVSGMSLRPRVNYLQ

HERVK_113

196

Q902F9
VEMNPEGYMTSRTVR

BCAM

196

P50895
FRTPVYTTSMRRNAM

DNAH10

4426

Q8IVF4
TIDRVGRIYPMAMSN

SLC22A1

396

O15245
SYQMERMFNTTRIPG

CPT1B

306

Q92523
NVVTVMLIGRYRDMR

MLNR

56

O43193
MLIGRYRDMRTTTNL

MLNR

61

O43193
PPRRVQARMLSASTM

PTPRF

416

P10586
SAQRTPVQMMYLREK

SERPINB2

226

P05120
MDYRRLLMSRVVPGQ

RIOK1

1

Q9BRS2
YRLGTIRPSSSVMNM

TINAGL1

176

Q9GZM7
RMSRMQSKEYPVVPR

TBX5

246

Q99593
RRFSGQPRSIMERIM

RNF170

161

Q96K19
GQMASYPLTLVRTRM

SLC25A41

296

Q8N5S1
VRKRRLSSYQISMEM

SCN3A

681

Q9NY46
RARMAVTPKEMYSNI

SLC25A42

156

Q86VD7
KTSRYFPTRVRSMVS

SLC4A8

716

Q2Y0W8
LQRRMSMYSQGTPET

RIPOR2

336

Q9Y4F9
LVSYPFDTVRRRMMM

SLC25A4

226

P12235
RQMTIYLPEVRKISM

TULP4

636

Q9NRJ4
PVRGARNQLRMYLTM

YIF1B

281

Q5BJH7
DTQTMESRGLRRYIM

UNC80

2551

Q8N2C7
GMRMNSRQLEKYPAT

MLN

86

P12872
TRGSQYRVESMMLRI

REV3L

2556

O60673
IRRSRLAMRPLSMSY

SPIRE1

391

Q08AE8
RDVVRPYQTMSNPMS

TRPM3

266

Q9HCF6
VPTATQTLMTMYRRR

TBC1D9

456

Q6ZT07
QTLMTMYRRRSPEEF

TBC1D9

461

Q6ZT07
MVSGMSLRPRVNYLQ

ERVK-10

956

P10266
AVTVMMDPNSTQRYR

XPO5

16

Q9HAV4
NKRQMSRIYPKGTRM

PLCB2

596

Q00722
DRVMIIRTMLYTPQE

RUVBL1

356

Q9Y265
MVYVTQSAGRLMRAI

SNRNP200

1081

O75643
DMTTLTIMRYLPREV

PSMC6

101

P62333
TTNEGEPMRIVYRMR

UBR4

4431

Q5T4S7
MCFIRTTRPETMVIY

TKTL1

441

P51854
SIRVPREKMVYMTVN

ZFY

286

P08048
SRSPMLQRRVYHSMA

KLHL32

476

Q96NJ5
LRYSGMMETIRIRRA

MYO7A

656

Q13402
MMETIRIRRAGYPIR

MYO7A

661

Q13402
SMRSMQHSPNLRTYR

NEBL

946

O76041