Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsteroid 11-beta-monooxygenase activity

CYP11B1 CYP11B2

5.68e-0521512GO:0004507
GeneOntologyMolecularFunctioncorticosterone 18-monooxygenase activity

CYP11B1 CYP11B2

5.68e-0521512GO:0047783
GeneOntologyBiologicalProcessmeiotic cell cycle process

ANKRD31 TDRD9 KCTD19 TOPBP1 MCM4 MSH4 PNMA5 MARF1 SHOC1 RAD54L MYBL1

4.39e-0626815011GO:1903046
GeneOntologyBiologicalProcessmeiotic cell cycle

ANKRD31 TDRD9 KCTD19 UTP14A TOPBP1 MCM4 MSH4 PNMA5 MARF1 SHOC1 RAD54L MYBL1

1.00e-0535015012GO:0051321
GeneOntologyBiologicalProcessmeiotic nuclear division

ANKRD31 TDRD9 KCTD19 TOPBP1 MSH4 PNMA5 MARF1 SHOC1 RAD54L MYBL1

1.06e-0524015010GO:0140013
GeneOntologyBiologicalProcessmeiosis I

ANKRD31 TDRD9 TOPBP1 MSH4 PNMA5 SHOC1 RAD54L MYBL1

1.23e-051471508GO:0007127
GeneOntologyBiologicalProcessmeiosis I cell cycle process

ANKRD31 TDRD9 TOPBP1 MSH4 PNMA5 SHOC1 RAD54L MYBL1

1.81e-051551508GO:0061982
GeneOntologyBiologicalProcessDNA recombination

ANKRD31 ATAD5 SMCHD1 TOPBP1 MCM4 MSH4 BRD8 SHOC1 SPIDR RAD54L TP53BP1

8.20e-0536815011GO:0006310
GeneOntologyBiologicalProcessreciprocal meiotic recombination

ANKRD31 TOPBP1 MSH4 SHOC1 RAD54L

1.28e-04671505GO:0007131
GeneOntologyBiologicalProcessreciprocal homologous recombination

ANKRD31 TOPBP1 MSH4 SHOC1 RAD54L

1.28e-04671505GO:0140527
HumanPhenoCaesarian section

CYP11B1 CYP11B2 MCM4 ASXL3

1.12e-0515514HP:0011410
MousePhenopituitary gland hyperplasia

CACNB4 CYP11B1 CYP11B2

2.21e-0571223MP:0000635
MousePhenoabnormal transitional stage T2 B cell morphology

CD22 AKAP13 PLCG2 SON

3.58e-05221224MP:0009920
MousePhenoabnormal urine progesterone level

CYP11B1 CYP11B2

7.55e-0521222MP:0011545
MousePhenoabnormal urine deoxycorticosterone level

CYP11B1 CYP11B2

7.55e-0521222MP:0011552
MousePhenodecreased urine corticosterone level

CYP11B1 CYP11B2

7.55e-0521222MP:0011550
MousePhenoincreased urine deoxycorticosterone level

CYP11B1 CYP11B2

7.55e-0521222MP:0011553
MousePhenoincreased urine progesterone level

CYP11B1 CYP11B2

7.55e-0521222MP:0011546
MousePhenoenlarged pituitary gland

CACNB4 CYP11B1 CYP11B2

1.35e-04121223MP:0000636
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DDX47 ITCH ILF3 MYCBP2 SMCHD1 UBR4 NACA UTP14A NOC3L MCM4 PRPF8 NEK9 WDR59 GTF3C5 RAB3GAP1 NUP155 AHNAK SNX27 AKAP13 KDM2A PLCG2 ASCC3 TP53BP1 SON

8.16e-0913531552429467282
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MYCBP2 UBR4 ZNF507 DVL3 NEK9 GTF3C5 PTPN13 ALMS1 AHNAK CRYBG3 ASCC3 CAMSAP1 MYBL2

5.54e-084181551334709266
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

SYNE1 SREBF2 RYR3 CCDC7 FSIP2 PTPN13 SRGAP1 SNX27 AKAP13

7.10e-08168155930631154
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ILF3 MYCBP2 ATAD5 UTP14A DVL3 PRPF8 EXOSC2 PTPN13 AHNAK MARF1 AKAP13 KDM2A ASCC3 CAMSAP1 YTHDF3 SON

1.72e-077241551636232890
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

POGLUT3 ITCH ILF3 MYCBP2 VEZT ATAD5 SYNE1 UBR4 BAG4 UTP14A NOC3L PRPF8 PDHX MRPS10 RAB3GAP1 PTPN13 NUP155 TMTC3 AKAP13 CRYBG3 ASCC3 ADGRL2 TP53BP1

2.03e-0714871552333957083
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

ILF3 BAG4 NACA UTP14A MCM4 PTPN13 AEBP2 AKAP13 SON

1.08e-06232155925515538
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

DDX47 MYCBP2 ATAD5 SMCHD1 NACA UTP14A NOC3L TOPBP1 PRPF8 EXOSC2 GTF3C5 PDHX NUP155 ASCC3 SON

1.71e-067591551535915203
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MIER2 UTP14A RNF213 NEK9 WDR59 REXO1 DENND3 RAB3GAP1 ALMS1 KDM2A ADGRF5 SPIDR

2.40e-064931551215368895
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ILF3 ATAD5 SMCHD1 NACA UTP14A NOC3L MCM4 PRPF8 NEK9 PTPN13 ALMS1 AHNAK CAMSAP1 TP53BP1 WDR44 SON

4.73e-069341551633916271
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ILF3 ATAD5 SMCHD1 UTP14A NOC3L TOPBP1 MCM4 PRPF8 TASOR2 BRD8 AHNAK MARF1 YTHDF3 TP53BP1 SON MYBL2

6.17e-069541551636373674
Pubmed

PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.

DDX47 ILF3 SMCHD1 NACA PRPF8 EXOSC2 GTF3C5 ASCC3

6.33e-06217155831685992
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

MYCBP2 SMCHD1 NEK9 GTF3C5 BRD8 PTPN13 ALMS1 AHNAK KDM2A ASCC3 TP53BP1 WDR44

7.14e-065491551238280479
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

DDX47 ILF3 ATAD5 SMCHD1 NACA UTP14A NOC3L TOPBP1 GC PRPF8 EXOSC2 AHNAK SON

7.87e-066521551331180492
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYCBP2 SMCHD1 UBR4 UTP14A NOC3L MCM4 PRPF8 TASOR2 NUP155 AHNAK ASCC3 TP53BP1 SON

8.00e-066531551322586326
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DDX47 ITCH VEZT ATAD5 FBF1 BAG4 RNF213 PDHX ACTL7A BRD8 TC2N ALMS1 CRYBG3 ASCC3 ADGRL2 UNC5D SON

1.09e-0511161551731753913
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ITCH SLC16A9 MYCBP2 VEZT MAPKAPK2 TTC21A NAIP SREBF2 RNF213 NFASC LRRC8D MAP3K12 NEK9 TASOR2 PTPN13 NAXD AKAP13 KDM2A SPIDR CREB3L2

1.12e-0514891552028611215
Pubmed

DNA cloning using in vitro site-specific recombination.

DDX47 GANC CYP11B2 MROH8 TC2N TMTC3 ZMYND10 NAA20 ADGRF5 ASCC3 DNASE1L1 YTHDF3 WDR44 PHLPP2

1.39e-057941551411076863
Pubmed

Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure.

CYP11B1 CYP11B2 AGTR2

1.40e-0511155320486282
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

MYCBP2 ATAD5 NACA RAB3GAP1 ALMS1 AHNAK CAMSAP1 MYBL2

1.40e-05242155834011540
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

DDX47 SYNE1 SMCHD1 UTP14A NOC3L RNF213 EXOSC2 ASCC3 SON

1.96e-05332155925693804
Pubmed

Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.

CYP11B1 CYP11B2

1.97e-052155223150505
Pubmed

GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.

CYP11B1 CYP11B2

1.97e-052155235012455
Pubmed

Role of genetic variation in regulation of aldosterone biosynthesis.

CYP11B1 CYP11B2

1.97e-052155221164264
Pubmed

AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation.

AHNAK TP53BP1

1.97e-052155233961796
Pubmed

The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity.

CYP11B1 CYP11B2

1.97e-05215528645611
Pubmed

Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain.

CYP11B1 CYP11B2

1.97e-052155212231255
Pubmed

A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I.

CYP11B1 CYP11B2

1.97e-052155220634641
Pubmed

Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase.

CYP11B1 CYP11B2

1.97e-05215521303253
Pubmed

Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans.

CYP11B1 CYP11B2

1.97e-05215521741400
Pubmed

Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.

CYP11B1 CYP11B2

1.97e-052155232540969
Pubmed

Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice.

CYP11B1 CYP11B2

1.97e-052155226047574
Pubmed

Aldosterone synthase knockout mouse as a model for sodium-induced endothelial sodium channel up-regulation in vascular endothelium.

CYP11B1 CYP11B2

1.97e-052155226324851
Pubmed

Microsatellite polymorphism analysis allows the individual assignment of the rat 11 beta-hydroxylase gene (Cyp11b1) and the rat aldosterone synthase gene (Cyp11b2) to chromosome 7 using rat x mouse somatic cell hybrids and identifies differences between and within various rat strains.

CYP11B1 CYP11B2

1.97e-05215527669222
Pubmed

Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron.

CYP11B1 CYP11B2

1.97e-052155222933298
Pubmed

Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase.

CYP11B1 CYP11B2

1.97e-05215522783417
Pubmed

Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.

CYP11B1 CYP11B2

1.97e-05215522256920
Pubmed

Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.

CYP11B1 CYP11B2

1.97e-052155220708777
Pubmed

Molecular genetic studies on the biosynthesis of aldosterone in humans.

CYP11B1 CYP11B2

1.97e-052155222217843
Pubmed

Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation.

CYP11B1 CYP11B2

1.97e-052155216396990
Pubmed

[123 I]Iodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes.

CYP11B1 CYP11B2

1.97e-052155218397978
Pubmed

Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.

CYP11B1 CYP11B2

1.97e-05215521518866
Pubmed

Procollagen I-expressing renin cell precursors.

CYP11B1 CYP11B2

1.97e-052155223761669
Pubmed

Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).

CYP11B1 CYP11B2

1.97e-05215522592361
Pubmed

Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice.

CYP11B1 CYP11B2

1.97e-052155223314847
Pubmed

Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects.

CYP11B1 CYP11B2

1.97e-052155217980006
Pubmed

Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

CYP11B1 CYP11B2

1.97e-052155216984984
Pubmed

Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) promotes non-homologous end joining and inhibits homologous recombination repair upon DNA damage.

SMCHD1 TP53BP1

1.97e-052155225294876
Pubmed

Evidence for local aldosterone synthesis in the large intestine of the mouse.

CYP11B1 CYP11B2

1.97e-052155235288482
Pubmed

Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.

CYP11B1 CYP11B2

1.97e-052155215731365
Pubmed

Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.

CYP11B1 CYP11B2

1.97e-052155217651452
Pubmed

Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.

CYP11B1 CYP11B2

1.97e-052155234743356
Pubmed

Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.

CYP11B1 CYP11B2

1.97e-052155220339375
Pubmed

Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.

CYP11B1 CYP11B2

1.97e-052155220808686
Pubmed

Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.

TOPBP1 TP53BP1

1.97e-052155231135337
Pubmed

Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets.

CYP11B1 CYP11B2

1.97e-052155221519965
Pubmed

Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.

CYP11B1 CYP11B2

1.97e-052155221625068
Pubmed

Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.

CYP11B1 CYP11B2

1.97e-052155216110193
Pubmed

Chimeric CYP11B2/CYP11B1 causing 11β-hydroxylase deficiency in Chinese patients with congenital adrenal hyperplasia.

CYP11B1 CYP11B2

1.97e-052155226066897
Pubmed

Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.

CYP11B1 CYP11B2

1.97e-052155218651133
Pubmed

A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern.

CYP11B1 CYP11B2

1.97e-052155222083159
Pubmed

Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity.

CYP11B1 CYP11B2

1.97e-052155215699546
Pubmed

Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway.

CYP11B1 CYP11B2

1.97e-052155218162527
Pubmed

Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism.

CYP11B1 CYP11B2

1.97e-052155238341019
Pubmed

Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.

CYP11B1 CYP11B2

1.97e-052155224837548
Pubmed

Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity.

CYP11B1 CYP11B2

1.97e-052155230046010
Pubmed

Familial and phenotypic associations of the aldosterone Renin ratio.

CYP11B1 CYP11B2

1.97e-052155219820005
Pubmed

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.

CYP11B1 CYP11B2

1.97e-052155222622494
Pubmed

Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production.

CYP11B1 CYP11B2

1.97e-052155215062555
Pubmed

Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.

CYP11B1 CYP11B2

1.97e-052155217075030
Pubmed

Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.

CYP11B1 CYP11B2

1.97e-052155217075029
Pubmed

CYP11B2-CYP11B1 haplotypes associated with decreased 11 beta-hydroxylase activity.

CYP11B1 CYP11B2

1.97e-052155215507509
Pubmed

Polymorphism of CYP11B2 determines salt sensitivity in Japanese.

CYP11B1 CYP11B2

1.97e-052155217296872
Pubmed

Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.

CYP11B1 CYP11B2

1.97e-052155218039983
Pubmed

Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.

CYP11B1 CYP11B2

1.97e-052155219029289
Pubmed

Isolation of human cDNA clones of myb-related genes, A-myb and B-myb.

MYBL1 MYBL2

1.97e-05215523060855
Pubmed

Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.

CYP11B1 CYP11B2

1.97e-052155215522937
Pubmed

The LIFEdb database in 2006.

DDX47 GANC MROH8 TC2N TMTC3 ZMYND10 NAA20 ADGRF5 ASCC3 DNASE1L1 YTHDF3 WDR44 PHLPP2

2.23e-057201551316381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

DDX47 GANC MROH8 TC2N TMTC3 ZMYND10 NAA20 ADGRF5 ASCC3 DNASE1L1 YTHDF3 WDR44 PHLPP2

2.30e-057221551315489336
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

POGLUT3 MYCBP2 VEZT NACA RNF213 WDR59 GTF3C5 ALMS1 TMTC3 AKAP13 CAMSAP1 YTHDF3 MYBL2

2.68e-057331551334672954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

OR51A4 DNAH3 CCDC73 TTC21A UBR4 TIGD4 RNF213 NFASC PRPF8 MROH8 AHNAK AGTR2 AKAP13

2.80e-057361551329676528
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

MYCBP2 ATAD5 SMCHD1 TOPBP1 GON4L NEK9 CDAN1 BRD8 ALMS1 AHNAK KDM2A CAMSAP1

3.49e-056451551225281560
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

SMCHD1 PRPF8 TMTC3 AHNAK CRYBG1 AKAP13 ASCC3

3.62e-05202155733005030
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

MYCBP2 SMCHD1 FBF1 UBR4 ZMYND10 ASXL3 AKAP13 CAMSAP1 SON

3.76e-05361155926167880
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

SMCHD1 UTP14A DVL3 TASOR2 AHNAK

4.29e-0586155537253089
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DDX47 ILF3 ATAD5 SMCHD1 UBR4 RNF213 MCM4 PRPF8 EXOSC2 GTF3C5 BRD8 NUP155 AHNAK KDM2A SON

5.16e-0510141551532416067
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

SMCHD1 MCM4 GTF3C5 TASOR2 ALMS1 AHNAK AEBP2 CRYBG1 ASCC3 TP53BP1

5.20e-054691551027634302
Pubmed

The roles of cAMP and cAMP-dependent protein kinase in the expression of cholesterol side chain cleavage and steroid 11 beta-hydroxylase genes in mouse adrenocortical tumor cells.

CYP11B1 CYP11B2

5.90e-05315522546938
Pubmed

Kidney function in mice lacking aldosterone.

CYP11B1 CYP11B2

5.90e-053155216118390
Pubmed

Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.

SLC26A4 AGTR2

5.90e-053155221921024
Pubmed

Aldosterone-induced coronary dysfunction in transgenic mice involves the calcium-activated potassium (BKCa) channels of vascular smooth muscle cells.

CYP11B1 CYP11B2

5.90e-053155217984374
Pubmed

The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics.

MYCBP2 MAP3K12

5.90e-053155218031680
Pubmed

Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11 beta-hydroxylase.

CYP11B1 CYP11B2

5.90e-05315522233742
Pubmed

Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system.

CYP11B1 CYP11B2

5.90e-053155233271253
Pubmed

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.

ITCH DVL3

5.90e-053155228455968
Pubmed

The prolactin regulatory element-binding regulates of the 11beta-hydroxylase gene.

CYP11B1 CYP11B2

5.90e-053155218801336
Pubmed

Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1.

CYP11B1 CYP11B2

5.90e-053155211932209
Pubmed

The myb gene family in cell growth, differentiation and apoptosis.

MYBL1 MYBL2

5.90e-053155210378697
Pubmed

Aldosterone postnatally, but not at birth, is required for optimal induction of renal mineralocorticoid receptor expression and sodium reabsorption.

CYP11B1 CYP11B2

5.90e-053155221467193
Pubmed

Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis.

CYP11B1 CYP11B2

5.90e-05315527750493
Pubmed

Antiaging Gene Klotho Regulates Adrenal CYP11B2 Expression and Aldosterone Synthesis.

CYP11B1 CYP11B2

5.90e-053155226471128
InteractionPTEN interactions

DDX47 ILF3 SMCHD1 NACA UTP14A TMCO6 PRPF8 EXOSC2 GTF3C5 RYR3 CCDC7 FSIP2 RAB3GAP1 PTPN13 SRGAP1 SNX27 CRYBG1 AKAP13 ASCC3 RAD54L TP53BP1 SON

1.68e-0692915122int:PTEN
GeneFamilyBeta-gamma crystallin domain containing

CRYBG1 CRYBG3

8.52e-0539721360
GeneFamilyCytochrome P450 family 11

CYP11B1 CYP11B2

8.52e-0539721007
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MIER2 GON4L MYBL1 MYBL2

1.86e-0453974532
GeneFamilyNeuroblastoma breakpoint family

NBPF4 NBPF6 NBPF5P

2.45e-0423973662
CoexpressionPUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP

ILF3 TOPBP1 MCM4 RAD54L MYBL2

1.74e-05551535M2180
CoexpressionGSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP

SERTAD2 TOPBP1 NEK9 TASOR2 NEFH NAA20 TP53BP1 WDR44

2.32e-051991538M5607
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN

ATAD5 RNF213 MCM4 PLXND1 ALMS1 CENPM RAD54L TP53BP1

2.40e-052001538M9215
CoexpressionBROWNE_HCMV_INFECTION_20HR_DN

SYNE1 HMBS TMCO6 PTPN13 DIAPH2 DNASE1L1

3.04e-051021536M5601
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ITCH MYCBP2 SMCHD1 TOPBP1 RAB3GAP1 PTPN13 AKAP13 CRYBG3 SPIDR ASCC3 YTHDF3 TP53BP1 MYBL1 SON PHLPP2 CREB3L2

4.31e-0585615316M4500
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP

VWA5B2 ILF3 ATAD5 TOPBP1 NFASC MCM4 MAP3K12 NUP155 ALMS1 CENPM CAMSAP1 RAD54L TP53BP1 MYBL1

4.76e-0568015314MM456
CoexpressionBROWNE_HCMV_INFECTION_14HR_DN

SYNE1 HMBS TMCO6 DENND3 ALMS1 DIAPH2 CRYBG1 AKAP13 ADGRL2

5.45e-052901539M13251
ToppCellCOVID-19|World / Disease, condition lineage and cell class

ILF3 MYCBP2 SMCHD1 RNF213 AHNAK AKAP13 KDM2A PLCG2 SON

3.63e-0820015597dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IKZF3 MYCBP2 ENPP1 SLC26A4 AHNAK AEBP2 ADGRF5 SON

3.53e-071901558d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

IKZF3 MYCBP2 SMCHD1 TMEM161B RNF213 MCM4 NUP155 RNF111

3.68e-0719115589454f642c3621370fa23640b631301346b300950
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CFAP73 SYNE1 C1orf87 TTC21A SHOC1 FAM227A PLCG2

4.14e-0719415584a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 TOPBP1 MCM4 SMYD2 NEFH CENPM RAD54L MYBL2

4.83e-071981558c78ff8fc71dfcba1ac0c373bc90ea7b87c5699a4
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DNAH3 CFAP73 SYNE1 C1orf87 TTC21A ZMYND10 FAM227A SPAG16

5.21e-0720015586a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYCBP2 SMCHD1 RNF213 AHNAK AKAP13 KDM2A PLCG2 SON

5.21e-07200155812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 POGLUT3 CCDC73 ALMS1 ZMYND10 FAM227A RAD54L

1.33e-061571557410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIER2 MAP3K12 PTPN13 AHNAK TRPM1 NKAPL PID1

2.09e-0616815572e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP73 ATAD5 MCM4 CENPM RAD54L MYBL1 MYBL2

3.18e-06179155780112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellPBMC-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

POGLUT3 ATAD5 MCM4 CENPM RAD54L MYBL1 MYBL2

3.55e-0618215574774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

IKZF3 MYCBP2 SMCHD1 TMEM161B RNF213 MCM4 NUP155

3.95e-061851557a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 CFAP73 C1orf87 TTC21A ZMYND10 CENPM FAM227A

4.39e-061881557606907c865bd2f11bb6474932716550f7723d858
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 SMCHD1 RNF213 SNCAIP TC2N TMTC3 PLCG2

5.22e-0619315579337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 CFAP73 SYNE1 C1orf87 TTC21A DIAPH2 FAM227A

5.58e-0619515573486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

POGLUT3 ATAD5 TOPBP1 MCM4 CENPM RAD54L MYBL2

5.77e-061961557df366d76ea55f49e349d622effa57c1535df8400
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 CFAP73 SYNE1 C1orf87 TTC21A ZMYND10 FAM227A

5.77e-061961557d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 SMCHD1 RNF213 SNCAIP TC2N PLCG2 MYBL1

5.97e-06197155757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 CFAP73 SYNE1 TTC21A ZMYND10 DIAPH2 FAM227A

5.97e-06197155771fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA5B2 DNAH3 CFAP73 SYNE1 C1orf87 TTC21A FAM227A

5.97e-06197155774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellmLN-B_cell-B_cell_cycling|B_cell / Region, Cell class and subclass

ZNF507 MCM4 NEB SMYD2 SPAG16 MYBL1 MYBL2

5.97e-0619715572071526fe46de8359ea118ff78581eb4454aa55a
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 CFAP73 SYNE1 TTC21A ZMYND10 DIAPH2 FAM227A

5.97e-061971557e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 CFAP73 SYNE1 TTC21A ZMYND10 DIAPH2 FAM227A

5.97e-061971557d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IKZF3 SYNE1 SMCHD1 RNF213 TC2N AHNAK MYBL1

6.59e-062001557d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH3 TDRD9 CFAP73 C1orf87 TTC21A ZMYND10 FAM227A

6.59e-06200155796701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SYNE1 SMCHD1 RNF213 AKAP13 PLCG2 PHLPP2

7.90e-061351556ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 KCTD19 MROH8 YAE1 MYBL1 ZNF445

1.24e-05146155640784fd7ef856f64edfb5a054c0c5d95c8150b20
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYP11B1 SYNE1 PLXND1 AHNAK MAMSTR MYBL1

1.50e-0515115560cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYP11B1 SYNE1 PLXND1 AHNAK MAMSTR MYBL1

1.50e-051511556b545823113a3450c5f841f7de48bf0937593544f
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 KCTD19 SLC34A3 CCDC7 ASXL3 ADGRF5

1.74e-0515515568fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

IKZF3 ENPP1 SYNE1 RNF213 PLCG2 MYBL1

1.80e-051561556afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 SERTAD2 HEMGN TSHR AMER2 CREB3L2

2.23e-0516215568ed9149ff53b285591354057055d072b203a47c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 SERTAD2 HEMGN TSHR AMER2 CREB3L2

2.23e-0516215567a05b05a33e1309fb5c0a8171db105ae68491815
ToppCell3'_v3-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

ATAD5 MCM4 TSHR CD22 CENPM MYBL2

2.31e-05163155647300dec94dc66e965bf71fafff0a9fd24fae968
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF507 PTPN13 TC2N AHNAK CRYBG1 MYBL1

2.64e-05167155683969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 ATAD5 ZMYND10 CENPM RAD54L MYBL1

2.83e-051691556b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 MCM4 CENPM RAD54L MYBL1 MYBL2

2.83e-0516915560bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATAD5 TOPBP1 HEMGN CENPM RAD54L MYBL2

2.92e-051701556badbe200e9d5003d23d115955b10b4ea767f6c26
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD5 WDR59 MRPS10 CENPM ASXL3 MYBL1

3.12e-0517215562b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 C1orf87 TTC21A ZMYND10 CENPM FAM227A

3.22e-051731556c3762655caa79ac4879876f470d32578a3c93b01
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD31 MCM4 EXOSC2 CENPM RAD54L MYBL2

3.22e-0517315569f892d756d05e573af018db64edb130ff187ad47
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 ATAD5 CENPM RAD54L MYBL1 MYBL2

3.33e-05174155684da9faff088d05233183b425385beb054c92d1b
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 MYCBP2 PTPN13 DMRT2 ADAMDEC1 ZMYND10

3.55e-0517615565e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 MYCBP2 PTPN13 DMRT2 ADAMDEC1 ZMYND10

3.66e-05177155614fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K12 SNCAIP ALMS1 SRGAP1 ADGRF5 MYBL1

3.66e-0517715568ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CFAP73 TTC21A NFASC ZMYND10 FAM227A

3.78e-0517815563b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

MIER2 ATAD5 UTP14A AEBP2 WDR44 ZNF445

3.90e-0517915569d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 MCM4 CENPM RAD54L MYBL1 MYBL2

3.90e-05179155688d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|COVID-19_Convalescent / Disease condition and Cell class

MIER2 ATAD5 UTP14A AEBP2 WDR44 ZNF445

3.90e-051791556366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 MCM4 CENPM RAD54L MYBL1 MYBL2

4.02e-051801556f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A4 DMRT2 SHOC1 ADGRF5 PLCG2 CRYBG3

4.15e-05181155630729f0364f719c044712a51453e22dc2c1a232b
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

ATAD5 HEMGN MCM4 RYR3 CENPM MYBL2

4.15e-051811556be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

IKZF3 ITCH SYNE1 RNF213 AHNAK MYBL1

4.41e-051831556f593a89b0aa8fffdfa403769916facfd30358521
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 MCM4 NEFH CENPM RAD54L MYBL2

4.41e-051831556769a022fe8568ec49e66f792cc5777e713a7571c
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 MCM4 NEFH CENPM RAD54L MYBL2

4.41e-051831556aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IKZF3 MYCBP2 SMCHD1 CD22 PLCG2 CREB3L2

4.55e-051841556911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MCM4 CENPM RAD54L MYBL1 PHLPP2 MYBL2

4.55e-0518415566b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IKZF3 MYCBP2 SMCHD1 CD22 PLCG2 CREB3L2

4.55e-051841556942b58ae7172bb5f97e55b032db9329d161854af
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MCM4 CENPM RAD54L MYBL1 PHLPP2 MYBL2

4.55e-051841556e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

IKZF3 CD22 CENPM RAD54L MYBL1 MYBL2

4.69e-0518515569766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 ATAD5 CENPM RAD54L MYBL1 MYBL2

4.69e-05185155630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MYCBP2 SMCHD1 TMEM161B RNF213 MCM4 NUP155

4.83e-0518615568571956890fc9894d766ba294a28e376b4aba428
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 PLXND1 PTPN13 TC2N AHNAK MYBL1

4.97e-051871556f1ba41f2ec703251a81c46e08d45e70210f298e7
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 CFAP73 C1orf87 ZMYND10 CENPM FAM227A

4.97e-051871556bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DDX47 IKZF3 SMCHD1 RNF213 TASOR2 TP53BP1

5.12e-051881556ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH3 CFAP73 C1orf87 TTC21A ZMYND10 FAM227A

5.28e-051891556a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN13 DMRT2 SHOC1 CRYBG1 ADGRF5 PLCG2

5.43e-051901556b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DNAH3 CFAP73 C1orf87 ZMYND10 CENPM FAM227A

5.43e-051901556426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 POGLUT3 CFAP73 ZMYND10 FAM227A SPAG16

5.59e-051911556683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.59e-0519115560c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.59e-051911556e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.59e-0519115569d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.59e-0519115561c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMCHD1 RNF213 TC2N AHNAK CRYBG1 KDM2A

5.76e-05192155647646d7e4990be85072987f92bf18d52f8da752e
ToppCellCOPD-Lymphoid|COPD / Disease state, Lineage and Cell class

IKZF3 SYNE1 SMCHD1 TC2N CRYBG1 MYBL1

5.76e-051921556064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLTP SLC26A4 DMRT2 SHOC1 ADGRF5 PLCG2

5.76e-0519215564842a55650fc4687c9184d498a8c05c259d15186
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IKZF3 SYNE1 SMCHD1 RNF213 TC2N MYBL1

5.76e-051921556ed1fb700d3e8f00495727d61e164fc0b70274fd0
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.76e-051921556d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.76e-051921556eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.76e-051921556354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellcontrol-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 RNF213 TC2N AHNAK MYBL1 SON

5.93e-05193155689d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 SMCHD1 SREBF2 CD22 AHNAK MYBL2

5.93e-05193155608696a99309f5b088692ddac8cca35413b5e810d
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

5.93e-0519315560e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 CFAP73 SYNE1 ZMYND10 FAM227A SPAG16

5.93e-051931556ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POGLUT3 ATAD5 MCM4 CENPM RAD54L MYBL2

5.93e-051931556e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

6.10e-051941556958e648138676d46698090b4046cb484083ae449
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLTP SLC26A4 DMRT2 SHOC1 ADGRF5 PLCG2

6.10e-0519415566165c00ec06a8393f23b0c62f679c143839b03b1
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 CFAP73 SYNE1 FAM227A ADGRF5 SPAG16

6.27e-051951556fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IKZF3 MYCBP2 RNF213 TSHR TC2N MYBL1

6.27e-05195155683c125223e7ca0f08a31414b3a16347912564765
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

POGLUT3 ATAD5 MCM4 CENPM RAD54L MYBL2

6.27e-051951556cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

POGLUT3 ATAD5 MCM4 CENPM RAD54L MYBL2

6.27e-051951556b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CFAP73 TTC21A ZMYND10 ANKDD1B FAM227A

6.27e-05195155679dc031258579ea328181dda33710dd897f1064a
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 CFAP73 SYNE1 FAM227A ADGRF5 SPAG16

6.27e-051951556eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH3 CFAP73 C1orf87 TTC21A ZMYND10 FAM227A

6.27e-05195155660067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POGLUT3 ATAD5 MCM4 CENPM RAD54L MYBL2

6.27e-05195155656d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH3 CFAP73 C1orf87 ZMYND10 FAM227A SPAG16

6.45e-051961556de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

IKZF3 SYNE1 RNF213 TC2N AHNAK MYBL1

6.45e-051961556af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellmLN-B_cell-B_cell_cycling|mLN / Region, Cell class and subclass

MCM4 NEB SMYD2 SPAG16 MYBL1 MYBL2

6.64e-051971556806dddcca85c82bd642008d930c8db16b613d88e
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IKZF3 SYNE1 RNF213 TC2N AHNAK MYBL1

6.64e-0519715562b3a56bb1d40bc1284a5931c4e7b373660de5402
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_Tem|COVID-19_Severe / Disease group, lineage and cell class

IKZF3 SYNE1 RNF213 TC2N AHNAK MYBL1

6.64e-051971556f0bac4d5c3160933ac3786cec8dadffb35d711ea
DiseaseGlucocorticoid-remediable aldosteronism

CYP11B1 CYP11B2

2.53e-0521492C1260386
Diseaseadrenal cortical adenoma (is_marker_for)

CYP11B1 CYP11B2

2.53e-0521492DOID:0050891 (is_marker_for)
DiseaseThyroid Hypoplasia

SLC26A4 TSHR

7.57e-0531492C0151516
Diseasecongenital adrenal hyperplasia (implicated_via_orthology)

CYP11B1 CYP11B2

7.57e-0531492DOID:0050811 (implicated_via_orthology)
DiseaseEpisodic Ataxia

CACNB4 UBR4

1.51e-0441492C1720189
Diseaseprimary hyperaldosteronism (is_implicated_in)

CYP11B1 CYP11B2

2.51e-0451492DOID:446 (is_implicated_in)
DiseaseThyroid Agenesis

SLC26A4 TSHR

2.51e-0451492C0749420
DiseaseConn Syndrome

CYP11B1 CYP11B2

3.75e-0461492C1384514
DiseaseHyperaldosteronism

CYP11B1 CYP11B2

3.75e-0461492C0020428
Diseaseprotocadherin alpha-7 measurement

CYP11B1 CYP11B2

5.23e-0471492EFO_0801973
DiseaseMASA syndrome (implicated_via_orthology)

NFASC TRPM1

5.23e-0471492DOID:0060246 (implicated_via_orthology)
Diseaseprimary ovarian insufficiency (is_implicated_in)

MSH4 DIAPH2

6.95e-0481492DOID:5426 (is_implicated_in)
Diseasesarcoma (is_implicated_in)

SREBF2 PDHX

6.95e-0481492DOID:1115 (is_implicated_in)
DiseaseGraves Disease

GC TSHR

8.91e-0491492C0018213
Diseaseprotein FAM163B measurement

CYP11B1 CYP11B2

8.91e-0491492EFO_0802936
Diseaseandrostenedione measurement

CYP11B1 CYP11B2

1.11e-03101492EFO_0007972
Diseasecell growth regulator with EF hand domain protein 1 measurement

CYP11B1 CYP11B2

1.35e-03111492EFO_0801461
Disease3-hydroxyanthranilate 3,4-dioxygenase measurement

CYP11B1 CYP11B2

1.35e-03111492EFO_0021862
Diseasecongenital hypothyroidism (implicated_via_orthology)

TSHR NEFH

2.21e-03141492DOID:0050328 (implicated_via_orthology)
Diseasemyelodysplastic syndrome (implicated_via_orthology)

PRPF8 MYBL2

2.55e-03151492DOID:0050908 (implicated_via_orthology)
DiseaseChronic Lymphocytic Leukemia

IKZF3 TOPBP1 PLCG2

2.73e-03551493C0023434
Diseasefocal segmental glomerulosclerosis

CCDC7 ALMS1

2.90e-03161492EFO_0004236
DiseaseN-acetylarginine measurement

SLC16A9 ALMS1

2.90e-03161492EFO_0021429
Diseasewhite matter hyperintensity measurement

FBF1 GON4L DENND3 GFM2 SNCAIP SHOC1

4.43e-033021496EFO_0005665
Diseasetotal lipids in small VLDL

ANKRD31 GC TP53BP1

4.77e-03671493EFO_0022148

Protein segments in the cluster

PeptideGeneStartEntry
ASKHISKPVQEPLVL

NAIP

441

Q13075
TPPSIKKIIHVLEKV

BAG4

376

O95429
IIIDSSPTALKHPEK

ATAD5

751

Q96QE3
VPKSHSEEALLKRLP

FAM227A

231

F5H4B4
SLALAKKPHIIIATP

DDX47

136

Q9H0S4
SKIPISIKHLTNLPS

AMER2

606

Q8N7J2
HLSKLPKDTALLLDP

AEBP2

476

Q6ZN18
TTKKGLHNLPLSPEL

CCDC7

21

Q96M83
LKITHVPEKPILSEL

CRYBG3

861

Q68DQ2
PVQDHLLFKKTLLPV

BRD8

1101

Q9H0E9
VHVTSKPVDKISVPN

AKAP13

521

Q12802
SQKPSDKHLDAIPIL

AGTR2

36

P50052
LPESHLPKEALKISV

ALMS1

1111

Q8TCU4
ILHKPSILQEKPSTE

ABITRAM

126

Q9NX38
VTAPDVDLHLKAPKI

AHNAK

4916

Q09666
SKTHNLELTLPVKPV

ADGRL2

1276

O95490
VEELKLSHNPLKSIP

CHAD

221

O15335
TVKKEKPLIQHPIDS

DIAPH2

66

O60879
KLSTKLPEQAEDHVP

CFAP73

16

A6NFT4
PETTLETLKHKINPS

DENND3

871

A2RUS2
EIVHKPGPITLTVAK

DVL3

321

Q92997
QEHIKPPVIKLLLSS

CAMSAP1

71

Q5T5Y3
SLAPIIVHVKVSSPK

CACNB4

326

O00305
APLPSHLISEIKDVL

CDAN1

1021

Q8IWY9
HSVLQRTEKKVLPSP

ASXL3

866

Q9C0F0
LFLKHEVPLQLPTVK

C1orf87

221

Q8N0U7
HLKTLLTPDDPDKSQ

NBPF4

126

Q96M43
KLTEPASVPIHKLSV

RAB3GAP1

366

Q15042
VHLIDKLPLPVTIKS

RAB40C

206

Q96S21
KEKLPVHVVVDPILS

RAD54L

136

Q92698
PDILKVLTKPLTHLI

SLC34A3

236

Q8N130
EPIKVALKTHLEPRT

KCTD19

361

Q17RG1
HSPVFLDKEILLKIP

PCDHB2

131

Q9Y5E7
IKLPVVTTDKQPHTL

ANKRD31

846

Q8N7Z5
PKKTTIENIQLPHTL

MCM4

626

P33991
SLLHKNPTVTHTKEP

SLC16A9

251

Q7RTY1
VPQTPLHTSRVLKED

MAPKAPK2

331

P49137
LKVASEAPLEHKPQV

NEK9

851

Q8TD19
ILVPKAAITHDIPNK

BLZF1

81

Q9H2G9
HPQTLQKLKVPIIDS

PRSS22

191

Q9GZN4
EPPSTNHEDILKKKL

FSIP2

1071

Q5CZC0
EVTQLIPKTKIPAHT

MLST8

206

Q9BVC4
LSRDTEKKSIIPLPH

NAA20

156

P61599
LTLKKEPLPAVIFHE

PID1

56

Q7Z2X4
LVLPTDELAEPKKSH

PLXND1

1676

Q9Y4D7
QISIPVKKEHIPGTL

PDHX

166

O00330
KLVVISDPHIKIDPD

GANC

431

Q8TET4
LVRNIIPPLSSTKHK

NAXD

56

Q8IW45
EPVSDILKLKTHLPT

ENPP1

906

P22413
QIKTSLHRLKPDTVP

GDF15

256

Q99988
LPSPSQLREKIIIKH

PLCG2

441

P16885
TILFIIKTEPSLHEP

OR51A4

46

Q8NGJ6
KDPHLENLDTIIKLP

MROH8

231

Q9H579
EASLPHQIKDILKPE

EXOSC2

261

Q13868
EIIVPKAPSHKTIQE

HEMGN

331

Q9BXL5
KIITPLNKDHIPITD

NUP155

471

O75694
VESHESSLILPPIKV

PDK2

261

Q15119
THLAEKKIPLIPVFL

OR56B4

266

Q8NH76
KQPLTVIVTPVSKLH

ITCH

66

Q96J02
LPKIPSVSTHIKVKS

NEFH

426

P12036
PTITKQSAKDHIVDP

NFASC

41

O94856
VTLPEKPVKLASHTR

FBF1

11

Q8TES7
PTKELHGTSIVPKLQ

KDM2A

806

Q9Y2K7
QISLHEPPKLLETVR

KLHL22

231

Q53GT1
SLVLVPLHTTPKAVE

DNASE1L1

141

P49184
PLHTTPKAVEKELNA

DNASE1L1

146

P49184
VLTKISKENTRHPLP

DMRT2

451

Q9Y5R5
LSETKDPLRVQPHLK

DNAH3

1186

Q8TD57
VKTKPLISTPLQSHL

CCDC73

1011

Q6ZRK6
VIKNTKEPPLSLTIH

ILF3

156

Q12906
KPQSEKVHQTLILDP

GON4L

671

Q3T8J9
ISEHPQKATTELPLL

CYP11B1

351

P15538
ASELKVHLAKSLPLP

CENPM

41

Q9NSP4
PHSKRPDILKTESLL

MAP3K12

501

Q12852
EHLLKPLPADKQIET

GLTP

6

Q9NZD2
KVAVELKDVPSPLHA

MARF1

56

Q9Y4F3
PPHKLELQTLKLEEL

MAMSTR

161

Q6ZN01
ISEHPQKATTELPLL

CYP11B2

351

P19099
PVASALIPVKDHKLL

CRYBG1

391

Q9Y4K1
LLLPSHKKSIEVQTP

FCRLB

66

Q6BAA4
DLVVHSLKDLPTVLP

HMBS

91

P08397
PQELEKKSIHLPEKS

IKZF3

356

Q9UKT9
QKALITTPLHKETTP

MYBL1

516

P10243
TTPLHKETTPKDQKE

MYBL1

521

P10243
LNVKHTPKLEIKVTP

CD22

236

P20273
QTIIPKIKLEPHEVD

CREB3L2

171

Q70SY1
KVPSNITDVAPHLTK

LRRC8D

601

Q7L1W4
LPKELPLISSHVDLS

MIER2

476

Q8N344
KISKVPSTPVHLTNE

PTPN13

1181

Q12923
HLLPIKDKSGIIPQT

NOC3L

151

Q8WTT2
IAHSPSLQSLKKPII

REXO1

791

Q8N1G1
HVDVPKDLTKPVVTI

MRPS10

51

P82664
IKSLHSIINPPIAKI

GFM2

56

Q969S9
VAPVEKTIKLLPSSH

SMCHD1

1021

A6NHR9
ISRHDSLKKIDSPPI

SRGAP1

921

Q7Z6B7
ELHSLVATLDPLIKP

SYNE1

5051

Q8NF91
ESKPLTIPKDIDLHL

TMEM161B

71

Q8NDZ6
TVSIKGILTLPKPVH

TC2N

261

Q8N9U0
SKLSPHLLEEPVITK

TDRD9

336

Q8NDG6
HLKTLLTPDDPDKSQ

NBPF5P

126

Q86XG9
HLKTLLTPDDPDKSQ

NBPF6

126

Q5VWK0
QKVVVTTPLHRDKTP

MYBL2

481

P10244
HLSLPQKSPSLAKEV

SHOC1

431

Q5VXU9
VKRVSPLKHQPETLE

SNCAIP

76

Q9Y6H5
KSKSPLPLTLQHLVA

MYCBP2

3151

O75592
HPILEKISAEKPIAN

MSH4

651

O15457
PIEEKKVPLSEHTIR

ACTL7A

286

Q9Y615
TPELTLHEIVCPKKL

ADAMDEC1

36

O15204
QKVEPKESPLHLVVI

ANKDD1B

296

A6NHY2
ATKDVIVHPLPLKLN

ADGRF5

556

Q8IZF2
SILPPHILTRLEEKK

ASCC3

1131

Q8N3C0
EAPIIHTSQDEKPLK

NKAPL

281

Q5M9Q1
LEPLLQKAVHKSPLS

PNMA5

266

Q96PV4
KVILKPDKTTITEPH

PRPF8

1951

Q6P2Q9
TLDPKTAHPNLVLSK

TRIM69

326

Q86WT6
VKSLSPKELVRIHVP

POGLUT3

76

Q7Z4H8
KISPDTVLHLILPES

RNF213

1556

Q63HN8
VKLQKVDPDSPLHSD

UBE2Q2

241

Q8WVN8
PSSVEVHPVLEKLKA

YTHDF3

386

Q7Z739
HITTLKIDQKPLPTT

PHLPP2

761

Q6ZVD8
APKTQESLKGILLHP

RNF111

26

Q6ZNA4
VKVNVPKVPIHSLVL

SLC26A4

646

O43511
TITEKHLELCPRPKQ

SPIDR

71

Q14159
PRTKSTETILHTPQK

SPIDR

226

Q14159
HRPLTEPSLQKTVLI

SERTAD2

51

Q14140
TSQVILPPHLEKIRD

RYR3

856

Q15413
KTVLPSKHAVPEVIE

SPAG16

96

Q8N0X2
EKIPPSTLVEIHLTA

SREBF2

706

Q12772
PAHPEVKNLKSIELA

TIGD4

291

Q8IY51
PDATPTELAKLVNKH

GC

431

P02774
RHLTPEPDIVASTKK

WDR44

216

Q5JSH3
EKIIPSILASTLPQH

TMCO6

226

Q96DC7
KELILTVLSVPPHEA

SNX27

126

Q96L92
SHSLKKDPVVPKEIV

TEX13C

376

A0A0J9YWL9
LLHKNKQPVTDPLLT

UTP14A

191

Q9BVJ6
IPVTAQPSKDVHVVK

TP53BP1

236

Q12888
EPENPSLHLKKIIVV

TTC21A

291

Q8NDW8
LDKKPLHEIKPQSIE

UNC5D

361

Q6UXZ4
VSIKPSKADNPHLLT

UNC5A

351

Q6ZN44
PPNTLHLLVRDVKKS

TRPM1

506

Q7Z4N2
IESISLLPEPEKTLH

WDR59

336

Q6PJI9
LKSITPPSHVVDLLD

YAE1

121

Q9NRH1
PDPLIHVIQKLSKIV

ZNF507

41

Q8TCN5
HKDAIVLAVKSLPPQ

VWA5B2

366

Q8N398
HESEKTPNVEPKILT

ZNF445

821

P59923
TKKSLPEERIHPNTL

TASOR2

191

Q5VWN6
ANISVHPDKLKVLLP

GTF3C5

271

Q9Y5Q8
HLTLTETQPPKKDLV

ZMYND10

316

O75800
VVPLKQPTLHIADKD

VEZT

521

Q9HBM0
ILDNKDLHPSTPLKT

TMTC3

36

Q6ZXV5
QKIHPERTPSEKLLA

SMYD2

116

Q9NRG4
TDPHKSSEITKNLLP

UBR4

1146

Q5T4S7
EIPVSHKPESKAALL

TOPBP1

451

Q92547
VSEPHILETLKPATK

SON

196

P18583
VPKLLSNPHTLLDKT

ZNF729

1221

A6NN14
PPSTQTLKLIETHLR

TSHR

51

P16473
KNHPVKEGTLTTLPL

NACA

686

E9PAV3
KIHTTPDTPEIRQVK

NEB

5031

P20929