Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	postsynaptic density	NRG1 DISC1 SPTBN1 ADGRB1 ADGRB3 ADAM10 BMPR2 PTPRZ1 RNF10 KALRN GRM3 SHANK3 USP6 SORCS3 TANC1	9.73e-05	451	221	15	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	NRG1 DISC1 SPTBN1 ADGRB1 ADGRB3 ADAM10 BMPR2 PTPRZ1 RNF10 KALRN GRM3 SHANK3 USP6 SORCS3 TANC1	1.80e-04	477	221	15	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	NRG1 DISC1 SPTBN1 ADGRB1 ADGRB3 ADAM10 BMPR2 PTPRZ1 RNF10 KALRN GRM3 SHANK3 USP6 SORCS3 TANC1	3.17e-04	503	221	15	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	NRG1 DISC1 SPTBN1 ADGRB1 ADGRB3 ADAM10 BMPR2 PTPRZ1 RNF10 KALRN GRM3 SHANK3 USP6 SORCS3 TANC1	4.76e-04	523	221	15	GO:0098984
GeneOntologyCellularComponent	axon	PCSK1 NRG1 MYCBP2 ADAM21 DISC1 SPTBN1 ADAM10 BMPR2 SACS PTPRZ1 SCN1A EXOC7 GOT1 CA2 ANK1 DCTN2 GRM3 AVIL UNC13C TANC1 CDH1	5.25e-04	891	221	21	GO:0030424
GeneOntologyCellularComponent	cilium	CENPF PSG6 DISC1 SEPTIN9 SPEF2 KIF9 KCNU1 PKM AKT1 GNA11 DNAH8 ODAD3 DRC7 IFT74 SHANK3 EYS C2CD3 BBS7 MROH2B VCAN ROPN1	5.81e-04	898	221	21	GO:0005929
Domain	Cadherin	DCHS2 CDHR2 FAT1 PCDH19 FAT4 FREM3 CELSR1 CDH1 CDH5 CDH16	1.14e-06	118	216	10	IPR002126
Domain	Cadherin_CS	DCHS2 CDHR2 FAT1 PCDH19 FAT4 CELSR1 CDH1 CDH5 CDH16	4.91e-06	109	216	9	IPR020894
Domain	CADHERIN_1	DCHS2 CDHR2 FAT1 PCDH19 FAT4 CELSR1 CDH1 CDH5 CDH16	6.61e-06	113	216	9	PS00232
Domain	Cadherin	DCHS2 CDHR2 FAT1 PCDH19 FAT4 CELSR1 CDH1 CDH5 CDH16	6.61e-06	113	216	9	PF00028
Domain	CADHERIN_2	DCHS2 CDHR2 FAT1 PCDH19 FAT4 CELSR1 CDH1 CDH5 CDH16	7.10e-06	114	216	9	PS50268
Domain	-	DCHS2 CDHR2 FAT1 PCDH19 FAT4 CELSR1 CDH1 CDH5 CDH16	7.10e-06	114	216	9	2.60.40.60
Domain	CA	DCHS2 CDHR2 FAT1 PCDH19 FAT4 CELSR1 CDH1 CDH5 CDH16	7.63e-06	115	216	9	SM00112
Domain	Cadherin-like	DCHS2 CDHR2 FAT1 PCDH19 FAT4 CELSR1 CDH1 CDH5 CDH16	8.19e-06	116	216	9	IPR015919
Domain	XAP5	FAM50B FAM50A	1.33e-04	2	216	2	IPR007005
Domain	XAP5	FAM50B FAM50A	1.33e-04	2	216	2	PF04921
Domain	EGF-like_dom	NRG1 ADAM21 MATN2 FAT1 UMODL1 FAT4 NRG2 LAMC2 EYS CELSR1 VCAN	1.59e-04	249	216	11	IPR000742
Domain	ASX_HYDROXYL	MATN2 FAT1 UMODL1 FAT4 EYS CELSR1 VCAN	1.62e-04	100	216	7	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	MATN2 FAT1 UMODL1 FAT4 EYS CELSR1 VCAN	2.32e-04	106	216	7	IPR000152
Domain	GAIN_dom_N	ADGRB1 ADGRB3 CELSR1	2.35e-04	11	216	3	IPR032471
Domain	GAIN	ADGRB1 ADGRB3 CELSR1	2.35e-04	11	216	3	PF16489
Domain	EGF-like_CS	NRG1 ADAM21 MATN2 FAT1 UMODL1 FAT4 NRG2 LAMC2 EYS CELSR1 VCAN	2.39e-04	261	216	11	IPR013032
Domain	EGF_2	NRG1 ADAM21 MATN2 FAT1 UMODL1 FAT4 NRG2 LAMC2 EYS CELSR1 VCAN	2.72e-04	265	216	11	PS01186
Domain	HELICASE_CTER	ATRX TDRD9 HFM1 DDX31 HLTF SMARCA4 DHX32	2.76e-04	109	216	7	PS51194
Domain	HELICASE_ATP_BIND_1	ATRX TDRD9 HFM1 DDX31 HLTF SMARCA4 DHX32	2.76e-04	109	216	7	PS51192
Domain	Helicase_ATP-bd	ATRX TDRD9 HFM1 DDX31 HLTF SMARCA4 DHX32	2.92e-04	110	216	7	IPR014001
Domain	Quinoprotein_ADH-like_supfam	EML6 EML5 PCDH19 WDR36 WDSUB1	3.61e-04	53	216	5	IPR011047
Domain	GPCR_2_brain_angio_inhib	ADGRB1 ADGRB3	3.96e-04	3	216	2	IPR008077
Domain	Neuregulin_C	NRG1 NRG2	3.96e-04	3	216	2	IPR002154
Domain	Neuregulin	NRG1 NRG2	3.96e-04	3	216	2	PF02158
Domain	EGF	NRG1 MATN2 FAT1 UMODL1 FAT4 NRG2 LAMC2 EYS CELSR1 VCAN	4.24e-04	235	216	10	SM00181
Domain	EGF_3	NRG1 ADAM21 MATN2 FAT1 UMODL1 FAT4 NRG2 EYS CELSR1 VCAN	4.24e-04	235	216	10	PS50026
Domain	-	ETFDH FOXRED2 AIFM3 MTO1 SDHA	4.67e-04	56	216	5	3.50.50.60
Domain	SPEC	SPTBN1 AKAP6 KALRN SYNE1	4.85e-04	32	216	4	SM00150
Domain	Spectrin/alpha-actinin	SPTBN1 AKAP6 KALRN SYNE1	4.85e-04	32	216	4	IPR018159
Domain	FAD/NAD-binding_dom	ETFDH FOXRED2 AIFM3 MTO1 SDHA	5.07e-04	57	216	5	IPR023753
Domain	EGF_CA	MATN2 FAT1 UMODL1 FAT4 EYS CELSR1 VCAN	5.47e-04	122	216	7	SM00179
Domain	EGF-like_Ca-bd_dom	MATN2 FAT1 UMODL1 FAT4 EYS CELSR1 VCAN	6.02e-04	124	216	7	IPR001881
Domain	EGF	NRG1 MATN2 FAT1 NRG2 EYS CELSR1 VCAN	6.63e-04	126	216	7	PF00008
Domain	-	NRG1 MYCBP2 HLA-DPA1 PSG6 MDGA2 PTPRJ UMODL1 PTPRZ1 CAMTA1 IL23R FNDC3B FLT1 KALRN NRG2 IGDCC3 PKHD1L1 VCAN CRTAM	7.25e-04	663	216	18	2.60.40.10
Domain	Pyridine_nuc-diS_OxRdtase_2	ETFDH AIFM3	7.87e-04	4	216	2	IPR000103
Domain	EGF_1	NRG1 ADAM21 FAT1 UMODL1 FAT4 NRG2 LAMC2 EYS CELSR1 VCAN	7.98e-04	255	216	10	PS00022
Domain	LAM_G_DOMAIN	FAT1 FAT4 EYS CELSR1	9.44e-04	38	216	4	PS50025
Domain	Laminin_G_2	FAT1 FAT4 EYS CELSR1	1.15e-03	40	216	4	PF02210
Domain	Pyr_redox_2	ETFDH FOXRED2 AIFM3	1.29e-03	19	216	3	PF07992
Domain	Ig-like_fold	NRG1 MYCBP2 HLA-DPA1 PSG6 MDGA2 PTPRJ UMODL1 PTPRZ1 CAMTA1 IL23R FNDC3B FLT1 KALRN NRG2 IGDCC3 PKHD1L1 VCAN CRTAM	1.47e-03	706	216	18	IPR013783
Domain	Apc4_WD40_dom	EML6 EML5 WDR36	1.50e-03	20	216	3	IPR024977
Domain	ANAPC4_WD40	EML6 EML5 WDR36	1.50e-03	20	216	3	PF12894
Domain	Helicase_C	ATRX TDRD9 HFM1 DDX31 HLTF SMARCA4	1.53e-03	107	216	6	PF00271
Domain	HELICc	ATRX TDRD9 HFM1 DDX31 HLTF SMARCA4	1.53e-03	107	216	6	SM00490
Domain	CH	SPEF2 SPTBN1 NAV3 PLS1 SYNE1	1.57e-03	73	216	5	PS50021
Domain	Helicase_C	ATRX TDRD9 HFM1 DDX31 HLTF SMARCA4	1.60e-03	108	216	6	IPR001650
Domain	LamG	FAT1 FAT4 EYS CELSR1	1.64e-03	44	216	4	SM00282
Domain	DEXDc	ATRX TDRD9 HFM1 DDX31 HLTF SMARCA4	1.68e-03	109	216	6	SM00487
Domain	CH-domain	SPEF2 SPTBN1 NAV3 PLS1 SYNE1	1.77e-03	75	216	5	IPR001715
Domain	Znf_TFIIS	TCEA3 POLR2I	1.94e-03	6	216	2	IPR001222
Domain	AA_TRANSFER_CLASS_1	GOT1 ACCSL	1.94e-03	6	216	2	PS00105
Domain	HELP	EML6 EML5	1.94e-03	6	216	2	PF03451
Domain	TFIIS_C	TCEA3 POLR2I	1.94e-03	6	216	2	PF01096
Domain	ZnF_C2C2	TCEA3 POLR2I	1.94e-03	6	216	2	SM00440
Domain	ZF_TFIIS_1	TCEA3 POLR2I	1.94e-03	6	216	2	PS00466
Domain	ZF_TFIIS_2	TCEA3 POLR2I	1.94e-03	6	216	2	PS51133
Domain	HELP	EML6 EML5	1.94e-03	6	216	2	IPR005108
Domain	P-loop_NTPase	ATRX TDRD9 ABCA12 SEPTIN9 SPEF2 GUF1 KIF9 NAV3 MFN2 HFM1 GNA11 CAMTA1 DNAH8 MPP7 DDX31 RFC3 HLTF SMARCA4 DHX32 DSEL	2.05e-03	848	216	20	IPR027417
Domain	FN3	MDGA2 PTPRJ UMODL1 PTPRZ1 IL23R FNDC3B KALRN IGDCC3	2.26e-03	199	216	8	PS50853
Domain	Spectrin	SPTBN1 KALRN SYNE1	2.28e-03	23	216	3	PF00435
Domain	ACTININ_2	SPTBN1 PLS1 SYNE1	2.28e-03	23	216	3	PS00020
Domain	ACTININ_1	SPTBN1 PLS1 SYNE1	2.28e-03	23	216	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN1 PLS1 SYNE1	2.28e-03	23	216	3	IPR001589
Domain	Growth_fac_rcpt_	MATN2 FAT1 UMODL1 FAT4 LAMC2 EYS CELSR1	2.29e-03	156	216	7	IPR009030
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCHS2 ATRX MYCBP2 SPTBN1 DEF8 ADGRB3 SRPK2 FMNL2 BICD1 TTLL12 GUF1 SACS RNF10 NAV3 PKM EXOC7 SDHA AKAP6 ACTR8 KALRN IFT74 SYNE1 CACHD1 PRPF8 MIPOL1 PPP4R3B POLR3B APPL2 SMARCA4 ZNF76	1.11e-09	1285	223	30	35914814
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	ATRX MYCBP2 ORC3 SRPK2 DNAJC10 MIOS MED27 DDX31 WDR36 MED16 POLR2I RFC3 PPP4R3B CEBPZ SMARCA4 NUP188 CDH1	4.65e-09	440	223	17	34244565
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ATRX RAPGEF5 SPTBN1 DEF8 FAM91A1 STX5 EML5 GNA11 CAMTA1 MTO1 COG5 TASOR AKAP6 WWP1 FAM171B E2F8 VCAN CDK5RAP2 NUP188 ACCSL PEAK1 CCDC171 CDH1	5.95e-07	1084	223	23	11544199
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	CENPF DISC1 SPTBN1 BICD1 EXOC7 AKAP6 KALRN DCTN2 SYNE1	6.25e-07	151	223	9	17043677
Pubmed	Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148.	PTPRJ FLT1 CDH5	1.04e-06	4	223	3	12771128
Pubmed	Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments.	PTPRJ FLT1 CDH5	1.04e-06	4	223	3	16893970
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ATRX MYCBP2 RPN2 SPTBN1 FRS2 SRPK2 TTLL12 GUF1 STX5 DNAJC10 SACS GMDS SDHA MPP7 DDX31 WDR36 DCTN2 SYNE1 TUBA1C PRPF8 EXOC5 IARS2 CEBPZ BBS7 CDK5RAP2 TANC1 PEAK1	1.22e-06	1487	223	27	33957083
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	NRG1 ATRX ORC3 SEPTIN9 SPTBN1 PSMD3 EXOC7 HNRNPLL DCTN2 TUBA1C RFC3 PRPF8 EXOC5 HLTF SMARCA4 USP39	1.31e-06	582	223	16	20467437
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ATRX ORC3 FAM91A1 SRPK2 GUF1 MIOS GNA11 MED27 TASOR TAF1L HNRNPLL WDR77 SDHA MPP7 FNDC3B DDX31 WDR36 MED16 SYNE1 TUBA1C POLR2I CELSR1 APPL2 CEBPZ SLC25A1 HLTF TANC1	1.38e-06	1497	223	27	31527615
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CENPF DISC1 SEPTIN9 ADGRB1 FRS2 FMNL2 TTLL12 MCM3AP PKM PLS1 SDHA FAT4 ANK1 IGDCC3 PRPF8 MIPOL1 NUP188 USP39	1.50e-06	736	223	18	29676528
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TPP2 RPN2 SPTBN1 PSMD3 LMBRD2 ADAM10 STX5 DNAJC10 EXOC7 COG5 WDR77 SDHA WDR36 DCTN2 TUBA1C RFC3 PRPF8 EXOC5 IARS2 POLR3B STRAP CEBPZ HLTF DHX32 NUP188 USP39	2.16e-06	1440	223	26	30833792
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	MYCBP2 DISC1 FAM91A1 DNAJC10 MTO1 EXOC7 WDR77 TUBA1C RFC3 PPP4R3B EXOC5 IARS2 STRAP BBS7 HLTF DHX32	2.21e-06	606	223	16	36538041
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MYCBP2 CENPF PSMD3 SRPK2 DNAJC10 MIOS EXOC7 TASOR DDX31 WDR36 MED16 RFC3 PRPF8 EXOC5 POLR3B STRAP CEBPZ SMARCA4	2.30e-06	759	223	18	35915203
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	RPN2 SPTBN1 PSMD3 ADAM10 FOXRED2 PTPRJ PKM WDR77 SDHA TUBA1C CACHD1 RFC3 PRPF8 STRAP SLC25A1 SMARCA4	2.56e-06	613	223	16	22268729
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	TPP2 RPN2 SEPTIN9 SPTBN1 ADGRB3 PSMD3 SRPK2 FAM50B AP1M1 EXOC7 SDHA HSP90AA4P DCTN2 PRPF8 PPP4R3B POLR3B STRAP FAM50A SMARCA4	2.69e-06	847	223	19	35235311
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CDHR2 SPTBN1 S100A14 ACOT7 PSMD3 FAT1 EML5 PTPRJ PKM AP1M1 GNA11 PLS1 GOT1 C11orf52 CA2 KALRN DCTN2 EYS APPL2 SLC25A1 CDK5RAP2	2.84e-06	1016	223	21	19056867
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FRS2 FAM91A1 FMNL2 FAT1 STX5 PKM TASOR HNRNPLL FAT4 WDR36 TUBA1C FAM171B RFC3 PKHD1L1 IARS2 GCC2 CDK5RAP2 PEAK1	3.19e-06	777	223	18	35844135
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	TPP2 CENPF SEPTIN9 ACOT7 PSMD3 PKM AP1M1 DNAH8 HNRNPLL RFC3 PRPF8 IARS2 POLR3B CEBPZ SLC25A1 SMARCA4 NUP188	3.49e-06	704	223	17	29955894
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ORC3 SEPTIN9 FAM91A1 PSMD3 AP1M1 EXOC7 COG5 SDHA WDR36 IFT74 TUBA1C PRPF8 EXOC5 POLR3B HLTF	3.88e-06	560	223	15	35241646
Pubmed	Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.	NRG1 AKT1 RLF VCAN SMARCA4	4.38e-06	38	223	5	29743679
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TPP2 SNX4 MYCBP2 RPN2 SPTBN1 FAM91A1 PSMD3 PTPN12 PTPRJ PTPRZ1 MIOS MPP7 DDX31 CACHD1 FAM171B PPP4R3B C2CD3 CEBPZ CDK5RAP2 TANC1 PEAK1	4.64e-06	1049	223	21	27880917
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ATRX RPN2 ORC3 FAM91A1 SRPK2 LMBRD2 TTLL12 LPIN1 DNAJC10 AP1M1 EXOC7 TASOR FNDC3B LAMC2 HLTF TANC1	5.36e-06	650	223	16	38777146
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ATRX CENPF RPN2 SPTBN1 PSMD3 TTLL12 PKM AP1M1 TDRD6 HNRNPLL WDR77 SDHA CA2 WDR36 SYNE1 TUBA1C RFC3 PRPF8 IARS2 STRAP CEBPZ SMARCA4 NUP188 USP39 PEAK1	5.66e-06	1425	223	25	30948266
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPP2 MYCBP2 CENPF RPN2 SPTBN1 TTLL12 MCM3AP SDHA DDX31 WDR36 TUBA1C PRPF8 IARS2 CEBPZ SMARCA4 NUP188	5.68e-06	653	223	16	22586326
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPP2 SEPTIN9 SPTBN1 ACOT7 PSMD3 SRPK2 FMNL2 SACS PTPRZ1 PKM MIOS SDHA GOT1 CA2 KALRN DCTN2 SYNE1 TUBA1C GRM3 SHANK3 APPL2 VCAN SMARCA4 TANC1 PEAK1	6.09e-06	1431	223	25	37142655
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	FAM91A1 PSMD3 FMNL2 LPIN1 DNAJC10 MIOS WDR36 WWP1 TUBA1C FMNL3 IARS2	6.43e-06	313	223	11	38270169
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MYCBP2 RPN2 ADGRB1 PSMD3 SERPINB4 MIOS MPP7 CA2 WDR36 POLR2I RFC3 PRPF8 USP6 POLR3B GCC2 HLTF NUP188 USP39 ZNF639 WDTC1	8.61e-06	1005	223	20	19615732
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT1 FAT4	8.93e-06	7	223	3	16059920
Pubmed	Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors.	PTPRZ1 AKT1 VCAN	8.93e-06	7	223	3	21976490
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	CENPF SPTBN1 EML6 FAT1 SACS DDX31 ANK1 LAMC2 PRPF8 EYS SMARCA4	1.12e-05	332	223	11	37433992
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	RPN2 PSMD3 PKM AP1M1 WDR77 PLS1 SDHA DCTN2 STRAP SLC25A1 NUP188	1.55e-05	344	223	11	36282215
Pubmed	Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.	DCHS2 FAT1 FAT4 CDH1	1.58e-05	24	223	4	26116661
Pubmed	Loss of Gata5 in mice leads to bicuspid aortic valve.	NRG1 TBX20 NOS3 CDH5	1.58e-05	24	223	4	21633169
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MYCBP2 SEPTIN9 SPTBN1 ADGRB1 ADGRB3 FAM91A1 PSMD3 SNRK STX5 SCN1A RNF10 NAV3 PKM AP1M1 HNRNPLL SDHA KALRN FAM171B SHANK3 OSBP PEAK1	1.60e-05	1139	223	21	36417873
Pubmed	Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease.	FRS2 BMPR2 VCAN SMARCA4	1.87e-05	25	223	4	26100917
Pubmed	Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.	MYCBP2 CENPF SPTBN1 BICD1	1.87e-05	25	223	4	12522145
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SEPTIN9 SPTBN1 FRS2 FAM91A1 FMNL2 BMPR2 STX5 PTPRJ PKM MPP7 FAM171B TANC1 PEAK1 CDH1	1.95e-05	565	223	14	25468996
Pubmed	Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.	FAT4 CELSR1 CDH5	2.12e-05	9	223	3	28705793
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CENPF RPN2 SEPTIN9 SPTBN1 PSMD3 SRPK2 PKM AP1M1 WDR77 SDHA WDR36 TUBA1C LAMC2 RFC3 PRPF8 IARS2 STRAP CEBPZ SLC25A1 SMARCA4 USP39 CDH1	2.21e-05	1257	223	22	36526897
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	MYCBP2 SPTBN1 STRADB RNF10 PKM AKAP6 FNDC3B NRAP KALRN SYNE1 WWP1 APPL2 CDK5RAP2	2.22e-05	497	223	13	23414517
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYCBP2 SEPTIN9 SPTBN1 ACOT7 PSMD3 GUF1 PTPN12 SERPINB4 MCM3AP PKM AP1M1 FNDC3B WDR36 GNE RFC3 PRPF8 RLF POLR3B CEBPZ SLC25A1 HLTF SMARCA4 TANC1	2.25e-05	1353	223	23	29467282
Pubmed	Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.	NRG1 ABCA12 CAMTA1 MGAT4C PLS1 KALRN ASXL3	2.67e-05	134	223	7	24324551
Pubmed	Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.	TDRD9 TDRD6 WDR77	3.02e-05	10	223	3	19584108
Pubmed	Haploinsufficiency of Klippel-Trenaunay syndrome gene Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherin.	AKT1 NOS3 CDH5	3.02e-05	10	223	3	27522498
Pubmed	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	FAM91A1 FAT4 FLT1 UNC13C DSEL	3.60e-05	58	223	5	19734545
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	RPN2 PSMD3 DNAJC10 PKM MIOS PLS1 SDHA GOT1 WWP1 TUBA1C OSBP USP39	3.90e-05	451	223	12	36168627
Pubmed	CD148 tyrosine phosphatase promotes cadherin cell adhesion.	PTPRJ CDH1	4.09e-05	2	223	2	25386896
Pubmed	Endothelial nitric oxide synthase is involved in calcium-induced Akt signaling in mouse skeletal muscle.	AKT1 NOS3	4.09e-05	2	223	2	19682597
Pubmed	CAMTA1, a novel antitumor gene, regulates proliferation and the cell cycle in glioma by inhibiting AKT phosphorylation.	AKT1 CAMTA1	4.09e-05	2	223	2	33316386
Pubmed	Association of the DISC1 and NRG1 genetic polymorphisms with schizophrenia in a Chinese population.	NRG1 DISC1	4.09e-05	2	223	2	27236031
Pubmed	Analysis of a cytoskeleton-associated kinase PEAK1 and E-cadherin in gastric cancer.	PEAK1 CDH1	4.09e-05	2	223	2	25445115
Pubmed	Microenvironmental regulation of epithelial-mesenchymal transitions in cancer.	VCAN CDH1	4.09e-05	2	223	2	23002209
Pubmed	Protective effect of 17beta-estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway.	AKT1 NOS3	4.09e-05	2	223	2	18004295
Pubmed	Dravet syndrome and SCN1A gene mutation related-epilepsies: cognitive impairment and its determinants.	SCN1A PCDH19	4.09e-05	2	223	2	21504426
Pubmed	Membrane domain organization of myelinated axons requires βII spectrin.	SPTBN1 AVIL	4.09e-05	2	223	2	24217619
Pubmed	Regulation of arterial blood pressure by Akt1-dependent vascular relaxation.	AKT1 NOS3	4.09e-05	2	223	2	21842346
Pubmed	NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis.	NRG1 NRG2	4.09e-05	2	223	2	34996744
Pubmed	ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.	ADAM10 CDH5	4.09e-05	2	223	2	18420943
Pubmed	Combination of AKT1 and CDH1 mutations predicts primary resistance to immunotherapy in dMMR/MSI-H gastrointestinal cancer.	AKT1 CDH1	4.09e-05	2	223	2	35705314
Pubmed	Kalirin: a novel genetic risk factor for ischemic stroke.	KALRN ROPN1	4.09e-05	2	223	2	20107840
Pubmed	The role and mechanism of asymmetric dimethylarginine in fetal growth restriction via interference with endothelial function and angiogenesis.	NOS3 FLT1	4.09e-05	2	223	2	32215825
Pubmed	ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis.	ADAM10 CDH1	4.09e-05	2	223	2	18200054
Pubmed	Dravet syndrome and Dravet syndrome-like phenotype: a systematic review of the SCN1A and PCDH19 variants.	SCN1A PCDH19	4.09e-05	2	223	2	33937968
Pubmed	E-cadherin enhances neuregulin signaling and promotes Schwann cell myelination.	NRG1 CDH1	4.09e-05	2	223	2	25988855
Pubmed	Clinical implications of a novel prognostic factor AIFM3 in breast cancer patients.	PTPN12 AIFM3	4.09e-05	2	223	2	31088422
Pubmed	A soluble form of the giant cadherin Fat1 is released from pancreatic cancer cells by ADAM10 mediated ectodomain shedding.	ADAM10 FAT1	4.09e-05	2	223	2	24625754
Pubmed	Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway.	AKT1 NOS3	4.09e-05	2	223	2	24708830
Pubmed	Lipid-binding role of betaII-spectrin ankyrin-binding domain.	SPTBN1 ANK1	4.09e-05	2	223	2	17716929
Pubmed	Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation.	AKT1 NOS3	4.09e-05	2	223	2	10376603
Pubmed	Heparin cofactor II, a serine protease inhibitor, promotes angiogenesis via activation of the AMP-activated protein kinase-endothelial nitric-oxide synthase signaling pathway.	NOS3 SERPIND1	4.09e-05	2	223	2	22904320
Pubmed	Bioinformatic Prediction of Novel Signaling Pathways of Apoptosis-inducing Factor, Mitochondrion-associated 3 (AIFM3) and Their Roles in Metastasis of Cholangiocarcinoma Cells.	AIFM3 FMNL3	4.09e-05	2	223	2	34949658
Pubmed	Dravet syndrome: a genetic epileptic disorder.	SCN1A PCDH19	4.09e-05	2	223	2	23093055
Pubmed	Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.	PKM NOS3	4.09e-05	2	223	2	31328803
Pubmed	Endothelial microparticles increase in mitral valve disease and impair mitral valve endothelial function.	AKT1 NOS3	4.09e-05	2	223	2	23384770
Pubmed	Erythropoietin increases endothelial biosynthesis of tetrahydrobiopterin by activation of protein kinase B alpha/Akt1.	AKT1 NOS3	4.09e-05	2	223	2	18519842
Pubmed	Pseudomonas aeruginosa Triggered Exosomal Release of ADAM10 Mediates Proteolytic Cleavage in Trans.	ADAM10 CDH1	4.09e-05	2	223	2	35163191
Pubmed	FMNL formins boost lamellipodial force generation.	FMNL2 FMNL3	4.09e-05	2	223	2	28327544
Pubmed	SPTBN1 suppresses the progression of epithelial ovarian cancer via SOCS3-mediated blockade of the JAK/STAT3 signaling pathway.	SPTBN1 SOCS3	4.09e-05	2	223	2	32516133
Pubmed	Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs.	AKT1 NOS3	4.09e-05	2	223	2	19570880
Pubmed	Dysregulation of PP2A-Akt interaction contributes to Sucrose non-fermenting related kinase (SNRK) deficiency induced insulin resistance in adipose tissue.	SNRK AKT1	4.09e-05	2	223	2	31420304
Pubmed	Suppression of SCC antigen promotes cancer cell invasion and migration through the decrease in E-cadherin expression.	SERPINB4 CDH1	4.09e-05	2	223	2	17016656
Pubmed	The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1.	NRG1 ADAM10	4.09e-05	2	223	2	19220854
Pubmed	Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site.	AKT1 NOS3	4.09e-05	2	223	2	11696579
Pubmed	Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathway.	AKT1 NOS3	4.09e-05	2	223	2	22808143
Pubmed	The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status.	AKT1 NOS3	4.09e-05	2	223	2	39332480
Pubmed	Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction.	NOS3 FLT1	4.09e-05	2	223	2	28115513
Pubmed	eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype.	NOS3 FLT1	4.09e-05	2	223	2	22282588
Pubmed	AKT has an anti-apoptotic role in ABCA12-deficient keratinocytes.	ABCA12 AKT1	4.09e-05	2	223	2	21633372
Pubmed	Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1.	NRG1 DISC1	4.09e-05	2	223	2	27613806
Pubmed	Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis.	FAM50B FAM50A	4.09e-05	2	223	2	10534398
Pubmed	Additive effect of NRG1 and DISC1 genes on lateral ventricle enlargement in first episode schizophrenia.	NRG1 DISC1	4.09e-05	2	223	2	19913623
Pubmed	A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.	FMNL2 FMNL3	4.09e-05	2	223	2	31751425
Pubmed	Asymmetric dimethylarginine induces endothelial nitric-oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1.	AKT1 NOS3	4.09e-05	2	223	2	23255608
Pubmed	Progress in imaging the effects of psychosis susceptibility gene variants.	NRG1 DISC1	4.09e-05	2	223	2	23253390
Pubmed	Altered cytokine profile, pain sensitivity, and stress responsivity in mice with co-disruption of the developmental genes Neuregulin-1×DISC1.	NRG1 DISC1	4.09e-05	2	223	2	27916686
Pubmed	Flt-1, but not Flk-1 mediates hyperpermeability through activation of the PI3-K/Akt pathway.	AKT1 FLT1	4.09e-05	2	223	2	17311300
Pubmed	Brg1 inhibits E-cadherin expression in lung epithelial cells and disrupts epithelial integrity.	SMARCA4 CDH1	4.09e-05	2	223	2	28801844
Pubmed	Cocoa: a new mouse model for platelet storage pool deficiency.	CA2 HPS3	4.09e-05	2	223	2	3408670
Pubmed	Bowes melanoma cells secrete heregulin, which can promote aggregation and counteract invasion of human mammary cancer cells.	NRG1 CDH1	4.09e-05	2	223	2	15609326
Pubmed	Phosphorylation of Akt at Thr308 regulates p-eNOS Ser1177 during physiological conditions.	AKT1 NOS3	4.09e-05	2	223	2	33993653
Interaction	SIRT6 interactions	ATRX MYCBP2 ORC3 SRPK2 FAT1 DNAJC10 MIOS AKT1 MED27 FAT4 DDX31 WDR36 MED16 POLR2I RFC3 PRPF8 HPS3 PPP4R3B CELSR1 CEBPZ SMARCA4 NUP188 CDH1	3.63e-07	628	218	23	int:SIRT6
Interaction	ANK2 interactions	ATRX MYCBP2 RAPGEF5 SPTBN1 ACOT7 ADAM10 KALRN SHANK3	1.13e-05	98	218	8	int:ANK2
Interaction	DSCAM interactions	ATRX SPTBN1 BICD1 GUF1 SACS SDHA KALRN SYNE1 PRPF8 POLR3B	1.77e-05	171	218	10	int:DSCAM
Interaction	NANS interactions	BICD1 PTPRJ PKM GOT1 PPP4R3B IARS2 CDH1 WDTC1	2.46e-05	109	218	8	int:NANS
Interaction	LAG3 interactions	HLA-DPA1 FAT1 CELSR1 CEBPZ	2.84e-05	17	218	4	int:LAG3
Interaction	SHANK3 interactions	SPTBN1 ACOT7 PSMD3 ADAM10 PKM EXOC7 SDHA GOT1 KALRN DCTN2 SYNE1 WWP1 TUBA1C GRM3 SHANK3 MIPOL1 SLC25A1	3.02e-05	496	218	17	int:SHANK3
Interaction	CDC42 interactions	RPN2 SEPTIN9 SPTBN1 FRS2 ACOT7 FAM91A1 PSMD3 FMNL2 BMPR2 FAT1 STX5 DNAJC10 PTPRJ MCM3AP FGD1 GNA11 COG5 SDHA MPP7 FNDC3B FAT4 SYNE1 TUBA1C RFX6 RFC3 FMNL3 USP6 CEBPZ SLC25A1 PEAK1 CDH1	3.96e-05	1323	218	31	int:CDC42
Interaction	SVIL interactions	ATRX MYCBP2 CENPF DISC1 SEPTIN9 SPTBN1 PKM WDR77 FLT1 AVIL CDH1	4.91e-05	233	218	11	int:SVIL
Interaction	NXF1 interactions	TPP2 ZNF142 DISC1 SPTBN1 ETFDH PSMD3 SRPK2 MCM3AP RNF10 MFN2 EXOC7 TAF1L SDHA GOT1 FAT4 WDR36 DCTN2 ANKRD10 SETD4 PRPF8 HPS3 OSBP POLR3B STRAP CEBPZ FAM50A HLTF ZNF76 TANC1 NUP188 WDTC1	5.40e-05	1345	218	31	int:NXF1
Interaction	MAGEA6 interactions	SNX4 S100A14 ACOT7 STX5 MIPOL1 EXOC5 ZNF76	5.50e-05	90	218	7	int:MAGEA6
GeneFamily	Cadherin related	DCHS2 CDHR2 FAT1 FAT4	7.37e-06	17	139	4	24
GeneFamily	Adhesion G protein-coupled receptors, subfamily B	ADGRB1 ADGRB3	1.75e-04	3	139	2	912
GeneFamily	WD repeat domain containing	EML6 EML5 WDR77 WDR36 MED16 STRAP WDSUB1 WDTC1	9.61e-04	262	139	8	362
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NRG1 MDGA2 FLT1 KALRN NRG2 IGDCC3	1.54e-03	161	139	6	593
GeneFamily	Exocyst complex	EXOC7 EXOC5	2.04e-03	9	139	2	1055
GeneFamily	Serpin peptidase inhibitors	SERPINI2 SERPINB4 SERPIND1	2.85e-03	37	139	3	739
GeneFamily	Maestro heat like repeat containing	MROH7 MROH2B	3.08e-03	11	139	2	636
GeneFamily	X-linked mental retardation\|RNA helicases	ATRX HFM1	3.08e-03	11	139	2	1168
GeneFamily	THAP domain containing	THAP5 THAP9	3.68e-03	12	139	2	65
Coexpression	GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_UP	ATRX MYCBP2 SEPTIN9 SPTBN1 DDX31 GNE POLR2I PELI2 HPS3 APPL2 HLTF CDH1	1.46e-07	200	221	12	M8644
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NRG1 SNX4 ATRX MYCBP2 CENPF SEPTIN9 SRPK2 ADAM10 BICD1 FAT1 PTPN12 SACS NAV3 COG5 TASOR GNE WWP1 RLF USP6 C2CD3 ELL2 GCC2 HLTF	1.09e-06	856	221	23	M4500
Coexpression	LAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES	SPTBN1 FMNL2 BMPR2 HIBCH FLT1 KALRN SYNE1 SHANK3 PEAK1	2.58e-06	137	221	9	M39241
Coexpression	AIZARANI_LIVER_C20_LSECS_3	BDP1 RAPGEF5 SNRK BMPR2 NOS3 FNDC3B FLT1 SOCS3 SHANK3 TANC1 PEAK1 CDH5	8.56e-06	295	221	12	M39121
Coexpression	GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN	SPEF2 EML5 PTPRZ1 IL23R WWP1 SOCS3 APPL2 TANC1 CDH5	2.25e-05	179	221	9	M6689
Coexpression	ERWIN_COHEN_BLOOD_LIVE_VACCINE_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_14DY_UP	THAP5 BDP1 TPP2 DNAJC10 HIBCH SACS MTO1 TASOR WWP1 TMEM161B PRELID3B PPP4R3B EXOC5 ELL2 CEBPZ CRTAM HLTF ZNF639	2.35e-05	687	221	18	M41022
Coexpression	GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	HLA-DPA1 BICD1 CAMTA1 HNRNPLL BATF SYNE1 CCDC92 ZNF335 CDH1	4.95e-05	198	221	9	M6511
Coexpression	GSE14308_TH17_VS_INDUCED_TREG_UP	ATRX MYCBP2 SPEF2 SACS PKM TBX20 DNAH8 CCDC92 EXOC5	5.35e-05	200	221	9	M3385
Coexpression	GSE21379_WT_VS_SAP_KO_CD4_TCELL_UP	ACOT7 PTPN12 GMDS NOS3 C11orf52 FAM50A CDK5RAP2 TANC1 CDH5	5.35e-05	200	221	9	M7499
Coexpression	GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_DN	PSMD3 TTLL12 ACTR8 WDR36 IFT74 PRELID3B GLCE USP39 WDSUB1	5.35e-05	200	221	9	M6020
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	CENPF ADGRB3 MDGA2 FMNL2 BICD1 EML5 PTPRZ1 PCDH19 TMEM161B IGDCC3 FAM171B APPL2 CEBPZ SLC25A1 DHX32 CCDC171	2.73e-07	328	216	16	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	BDP1 CENPF MDGA2 BICD1 EML5 PTPRZ1 PCDH19 IGDCC3 FAM171B SLC25A1 DHX32	2.72e-05	232	216	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	NRG1 RAPGEF5 SPTBN1 BMPR2 PTPN12 HIBCH GMDS NOS3 FLT1 PELI2 PKHD1L1 SHANK3 VCAN	1.24e-11	189	220	13	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SYNE1 SHANK3 FMNL3 PEAK1 CDH5	1.72e-11	194	220	13	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SYNE1 SOCS3 SHANK3 FMNL3 CDH5	2.23e-11	198	220	13	31ba87552be97c9b78c9e82f98e96699ccb19824
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SOCS3 SHANK3 FMNL3 PEAK1 CDH5	2.23e-11	198	220	13	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SHANK3 FMNL3 PEAK1 CDH5	3.17e-10	197	220	12	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SHANK3 FMNL3 PEAK1 CDH5	3.17e-10	197	220	12	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 MDGA2 FAT1 NRK NAV3 FAT4 ANK1 KALRN PKHD1L1 ASXL3 UNC13C	2.15e-09	184	220	11	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 MDGA2 FAT1 NRK NAV3 FAT4 ANK1 KALRN PKHD1L1 ASXL3 UNC13C	2.15e-09	184	220	11	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 MDGA2 FAT1 NRK NAV3 FAT4 ANK1 KALRN PKHD1L1 ASXL3 UNC13C	2.15e-09	184	220	11	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX RAPGEF5 SPTBN1 BMPR2 SACS NRK NOS3 FLT1 PKHD1L1 TANC1 CDH5	2.40e-09	186	220	11	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	NRG1 RAPGEF5 SPTBN1 BMPR2 PTPN12 HIBCH GMDS FLT1 PELI2 PKHD1L1 SHANK3	2.84e-09	189	220	11	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	NRG1 RAPGEF5 SPTBN1 BMPR2 PTPN12 HIBCH GMDS FLT1 PELI2 PKHD1L1 SHANK3	3.54e-09	193	220	11	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NOS3 FLT1 KALRN SHANK3 FMNL3 PEAK1 CDH5	3.74e-09	194	220	11	f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NOS3 FLT1 KALRN SHANK3 FMNL3 PEAK1 CDH5	3.74e-09	194	220	11	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAPGEF5 SPEF2 SNRK SRPK2 BICD1 BMPR2 FAT4 FLT1 CACHD1 SHANK3 CDH5	3.74e-09	194	220	11	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	ASK454-Endothelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	RAPGEF5 MATN2 SNRK BMPR2 NOS3 FAT4 FLT1 SOCS3 FAM171B SHANK3 CDH5	4.16e-09	196	220	11	14dd6956ef420b660be0baf52a66960e57d75d16
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SHANK3 FMNL3 PEAK1 CDH5	4.16e-09	196	220	11	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	4.63e-09	198	220	11	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NAV3 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	4.63e-09	198	220	11	07701c73137947ed4a27e225975329235bbb8734
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	NRG1 FAT1 SERPINB4 OVCH2 LAMC2 CAMK1G CACHD1 CELSR1 TANC1 CDH1	2.48e-08	181	220	10	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 EFCAB13 MDGA2 BICD1 FAT1 NAV3 MGAT4C VWA3A SYNE1 VCAN	2.48e-08	181	220	10	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 EFCAB13 MDGA2 BICD1 FAT1 NAV3 MGAT4C VWA3A SYNE1 VCAN	2.48e-08	181	220	10	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	NRG1 S100A14 FAT1 PTPRZ1 SERPINB4 LAMC2 CACHD1 CELSR1 ASXL3 CDH1	2.62e-08	182	220	10	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	S100A14 FAT1 SERPINB4 OVCH2 LAMC2 CAMK1G CACHD1 CELSR1 TANC1 CDH1	2.76e-08	183	220	10	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	RAPGEF5 ADGRB3 NAV3 NOS3 FLT1 KALRN SYNE1 SHANK3 FMNL3 CDH5	2.76e-08	183	220	10	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 NAV3 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	3.38e-08	187	220	10	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRG1 RAPGEF5 MATN2 GMDS NOS3 FLT1 PELI2 PKHD1L1 SHANK3 UNC13C	3.74e-08	189	220	10	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	NRG1 RAPGEF5 BMPR2 PTPN12 HIBCH GMDS FLT1 PELI2 PKHD1L1 SHANK3	4.56e-08	193	220	10	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAPGEF5 SPEF2 SNRK SRPK2 BICD1 FAT4 FLT1 CACHD1 SHANK3 CDH5	4.56e-08	193	220	10	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 ADGRB3 BMPR2 NAV3 FLT1 CACHD1 SHANK3 FMNL3 PEAK1 CDH5	4.78e-08	194	220	10	74a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	5.27e-08	196	220	10	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 ADGRB3 BMPR2 NAV3 FLT1 KALRN CACHD1 PKHD1L1 SHANK3 CDH5	5.27e-08	196	220	10	22767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 BMPR2 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	5.27e-08	196	220	10	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 ADGRB3 BMPR2 NAV3 FLT1 KALRN CACHD1 PKHD1L1 SHANK3 CDH5	5.27e-08	196	220	10	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 NAV3 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	5.53e-08	197	220	10	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 NOS3 FLT1 KALRN SYNE1 SHANK3 FMNL3 CDH5	5.80e-08	198	220	10	440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 NOS3 FLT1 KALRN SYNE1 SHANK3 FMNL3 CDH5	5.80e-08	198	220	10	451003a21162eeae90739fdb502bb50b362d80c8
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ATRX RAPGEF5 SPEF2 SPTBN1 SNRK BMPR2 NOS3 FAT4 FLT1 CDH5	6.37e-08	200	220	10	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 ADGRB3 FMNL2 NOS3 FLT1 SYNE1 PKHD1L1 SHANK3 CDH5	2.00e-07	172	220	9	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAPGEF5 SPTBN1 NAV3 MGAT4C KALRN PKHD1L1 SHANK3 PEAK1 CDH5	2.67e-07	178	220	9	ad3de3e03a401dac64431a541899445262246347
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	S100A14 FAT1 PTPRZ1 SERPINB4 LAMC2 CACHD1 CELSR1 ASXL3 CDH1	3.22e-07	182	220	9	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RAPGEF5 SPTBN1 ADAM10 MGAT4C MPP7 KALRN PKHD1L1 SHANK3 CDH5	3.70e-07	185	220	9	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RAPGEF5 SPTBN1 ADAM10 MGAT4C MPP7 KALRN PKHD1L1 SHANK3 CDH5	3.70e-07	185	220	9	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAPGEF5 SPTBN1 NAV3 MGAT4C KALRN PKHD1L1 SHANK3 PEAK1 CDH5	3.87e-07	186	220	9	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RAPGEF5 SPTBN1 NOS3 FLT1 KALRN SYNE1 SHANK3 PEAK1 CDH5	4.43e-07	189	220	9	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RAPGEF5 SPTBN1 BMPR2 FLT1 KALRN SYNE1 SHANK3 TANC1 CDH5	4.43e-07	189	220	9	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 SPTBN1 BMPR2 FLT1 KALRN SYNE1 SHANK3 TANC1 CDH5	4.63e-07	190	220	9	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN1 BMPR2 FAT4 FLT1 KALRN SYNE1 SHANK3 TANC1 CDH5	4.63e-07	190	220	9	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX SPTBN1 ADAM10 TASOR MGAT4C WWP1 PPP4R3B B4GALNT2 CDH1	4.84e-07	191	220	9	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX SPTBN1 ADAM10 TASOR MGAT4C WWP1 PPP4R3B B4GALNT2 CDH1	4.84e-07	191	220	9	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAPGEF5 SPTBN1 SNRK BMPR2 FLT1 CACHD1 FMNL3 TANC1 CDH5	4.84e-07	191	220	9	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN1 BMPR2 FAT4 FLT1 KALRN SYNE1 SHANK3 TANC1 CDH5	4.84e-07	191	220	9	f229abf69a1217194f74b0502486907e07dba989
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	RAPGEF5 BMPR2 NOS3 FLT1 KALRN SYNE1 PKHD1L1 SHANK3 CDH5	4.84e-07	191	220	9	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX SPTBN1 ADAM10 TASOR MGAT4C WWP1 PPP4R3B B4GALNT2 CDH1	4.84e-07	191	220	9	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	NRG1 RAPGEF5 MATN2 HIBCH GMDS PELI2 PKHD1L1 VCAN UNC13C	5.06e-07	192	220	9	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	RAPGEF5 BMPR2 NOS3 FLT1 KALRN SYNE1 PKHD1L1 SHANK3 CDH5	5.06e-07	192	220	9	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	S100A14 FAT1 PTPRZ1 SERPINB4 LAMC2 CACHD1 CELSR1 TANC1 CDH1	5.06e-07	192	220	9	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	IPF-Endothelial-Lymphatic\|IPF / Disease state, Lineage and Cell class	RAPGEF5 SPTBN1 MGAT4C KALRN FAM171B PKHD1L1 SHANK3 TANC1 CDH5	5.06e-07	192	220	9	2496edd8f3a41146d418879de9ee2ccc7857431f
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAPGEF5 DISC1 SPEF2 SNRK FAT4 FLT1 CACHD1 SHANK3 CDH5	5.28e-07	193	220	9	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAPGEF5 SPEF2 SNRK SRPK2 BICD1 FAT4 FLT1 SHANK3 CDH5	5.28e-07	193	220	9	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RAPGEF5 SPTBN1 SNRK FLT1 KALRN SYNE1 SHANK3 TANC1 CDH5	5.28e-07	193	220	9	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 PTPN12 FAT4 FLT1 SYNE1 PKHD1L1 SHANK3 CDH5	5.28e-07	193	220	9	456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DPA1 ADGRB3 SNRK NOS3 FLT1 KALRN PKHD1L1 SHANK3 CDH5	5.51e-07	194	220	9	cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAPGEF5 SNRK BMPR2 FAT4 FLT1 CACHD1 SHANK3 TANC1 CDH5	5.51e-07	194	220	9	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 ADGRB3 FMNL2 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	5.51e-07	194	220	9	b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	NRG1 RAPGEF5 BMPR2 GMDS NOS3 FLT1 PELI2 PKHD1L1 SHANK3	5.51e-07	194	220	9	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 FMNL2 FLT1 SYNE1 PKHD1L1 SHANK3 CDH5	5.51e-07	194	220	9	ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAPGEF5 SNRK BMPR2 FAT4 FLT1 CACHD1 SHANK3 TANC1 CDH5	5.51e-07	194	220	9	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 ADGRB3 BMPR2 NAV3 FLT1 KALRN SHANK3 FMNL3 CDH5	5.51e-07	194	220	9	e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB3 SNRK BMPR2 NOS3 FLT1 KALRN SOCS3 SHANK3 CDH5	5.76e-07	195	220	9	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	6.01e-07	196	220	9	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	6.01e-07	196	220	9	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	ASK454-Endothelial-Endothelium\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	MATN2 SNRK BMPR2 NOS3 FAT4 FLT1 SOCS3 SHANK3 CDH5	6.01e-07	196	220	9	2b777a2026b56839112fd179f2db482c49f4594a
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RAPGEF5 SPTBN1 SNRK BMPR2 FLT1 KALRN SYNE1 SHANK3 CDH5	6.01e-07	196	220	9	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	RAPGEF5 SPTBN1 SNRK BMPR2 FLT1 KALRN SYNE1 SHANK3 CDH5	6.01e-07	196	220	9	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 NOS3 FLT1 KALRN SHANK3 FMNL3 CDH5	6.01e-07	196	220	9	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	nucseq-Endothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RAPGEF5 SPTBN1 BMPR2 FLT1 KALRN PKHD1L1 SHANK3 TANC1 CDH5	6.27e-07	197	220	9	ebf9be068eaa658493fa7884fd19f34642922acb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 ADGRB3 FLT1 KALRN SYNE1 SHANK3 FMNL3 CDH5	6.54e-07	198	220	9	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	ASK452-Endothelial-Endothelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	RAPGEF5 SPTBN1 SNRK BMPR2 NOS3 FLT1 SOCS3 SHANK3 CDH5	6.54e-07	198	220	9	e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAPGEF5 SPTBN1 SNRK BICD1 BMPR2 FAT4 FLT1 SHANK3 CDH5	6.54e-07	198	220	9	d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCell	ASK452-Endothelial\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	RAPGEF5 SPTBN1 SNRK BMPR2 NOS3 FLT1 SOCS3 SHANK3 CDH5	6.82e-07	199	220	9	0bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell	Tracheal-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DPA1 RAPGEF5 SPTBN1 BMPR2 NOS3 FLT1 SOCS3 SHANK3 CDH5	7.11e-07	200	220	9	71ba0e48ca4ded077f2b96a0cf4f2331f2e25d15
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ATRX RAPGEF5 SPEF2 SPTBN1 SNRK BMPR2 FAT4 FLT1 CDH5	7.11e-07	200	220	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DPA1 RAPGEF5 SPTBN1 BMPR2 NOS3 FLT1 SOCS3 SHANK3 CDH5	7.11e-07	200	220	9	06ffa5baad3e699cf66d8b2c7513649e1d2c7e62
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D122\|Adult / Lineage, Cell type, age group and donor	UMODL1 NOS3 FLT1 SMCO3 KALRN PKHD1L1 SHANK3 SUN3	1.36e-06	160	220	8	0cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 SPTBN1 KCNU1 FLT1 SYNE1 PKHD1L1 SHANK3 TANC1	2.04e-06	169	220	8	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	ABCA12 SPTBN1 NRK FLT1 KALRN SYNE1 SHANK3 CDH5	2.23e-06	171	220	8	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 ADGRB3 NAV3 FLT1 KALRN CACHD1 SHANK3 CDH5	3.14e-06	179	220	8	8f9e538c822940785130297712b75131812a4603
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZSCAN12 CENPF RAPGEF5 BICD1 FLT1 TUBA1C SOCS3 SHANK3	3.14e-06	179	220	8	327cc39161741ddbc4e8d45b9b3d30b3ce508929
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF5 BMPR2 SACS NAV3 FLT1 TANC1 PEAK1 CDH5	3.40e-06	181	220	8	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAPGEF5 NAV3 MGAT4C KALRN PKHD1L1 SHANK3 PEAK1 CDH5	3.40e-06	181	220	8	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RAPGEF5 SPTBN1 BMPR2 FLT1 KALRN SYNE1 SHANK3 CDH5	3.40e-06	181	220	8	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 RAPGEF5 SPTBN1 BMPR2 FLT1 KALRN SHANK3 CDH5	3.55e-06	182	220	8	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	RAPGEF5 SPTBN1 BMPR2 NRK FLT1 KALRN SHANK3 CDH5	3.55e-06	182	220	8	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAPGEF5 SPTBN1 NAV3 MGAT4C KALRN PKHD1L1 SHANK3 CDH5	3.69e-06	183	220	8	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	Control-Endothelial_cells-Pulmonary_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	BMPR2 NAV3 NOS3 FLT1 KALRN PKHD1L1 SHANK3 CDH5	3.69e-06	183	220	8	46be9f96755c7b65aeac061d95d15abeb6466034
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RAPGEF5 SPTBN1 SNRK FMNL2 FLT1 KALRN SHANK3 ELL2	4.00e-06	185	220	8	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	RAPGEF5 SPTBN1 FLT1 KALRN SYNE1 SHANK3 TANC1 CDH5	4.00e-06	185	220	8	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RAPGEF5 BMPR2 NOS3 FLT1 KALRN PKHD1L1 SHANK3 CDH5	4.33e-06	187	220	8	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 ADGRB3 MDGA2 KALRN SYNE1 CAMK1G GRM3 ELL2	4.33e-06	187	220	8	15d6e158562d7d85af3ceaf955439b379c8fce81
Disease	Colorectal Carcinoma	ABCA12 ETFDH IPP LPIN1 FAT1 SACS MCM3AP AKT1 DNAH8 AKAP6 KALRN SYNE1 SETD4 HPS3 OSBP STRAP B4GALNT2 DSEL CDH1 CDH5	2.69e-07	702	216	20	C0009402
Disease	bipolar disorder (is_implicated_in)	NRG1 DISC1 AKT1 SYNE1	5.75e-05	29	216	4	DOID:3312 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease (is_implicated_in)	NRG1 MFN2 POLR3B	8.11e-05	12	216	3	DOID:10595 (is_implicated_in)
Disease	internet addiction disorder	NRG1 DISC1 ANK1 GRM3	9.67e-05	33	216	4	EFO_0803368
Disease	cardiomyopathy (biomarker_via_orthology)	ADAM10 NOS3 GOT1	1.05e-04	13	216	3	DOID:0050700 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	NRG1 CENPF EFCAB13 ADAM10 BMPR2 STX5 MROH7 AP1M1 AKT1 NOS3 AKAP6 FNDC3B FLT1 ANK1 KALRN SYNE1 MOSPD1 DHX32 CDH1 CDH5	1.34e-04	1074	216	20	C0006142
Disease	psychotic disorder (is_implicated_in)	NRG1 DISC1	1.59e-04	3	216	2	DOID:2468 (is_implicated_in)
Disease	neutrophil gelatinase-associated lipocalin measurement	PSMD3 ELL2	1.59e-04	3	216	2	EFO_0021964
Disease	acute graft vs. host disease, donor genotype effect measurement	MDGA2 KALRN EYS	1.65e-04	15	216	3	EFO_0004599, EFO_0007892
Disease	Schizophrenia	NRG1 DISC1 SHANK3	2.91e-04	18	216	3	cv:C0036341
Disease	diabetic retinopathy (biomarker_via_orthology)	MFN2 AKT1 NOS3 FLT1	3.29e-04	45	216	4	DOID:8947 (biomarker_via_orthology)
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	PTPRJ SMARCA4 CDH1	3.44e-04	19	216	3	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	PTPRJ SMARCA4 CDH1	3.44e-04	19	216	3	C2936783
Disease	QRS duration	NRG1 PTPRJ TBX20 COG5 MGAT4C PLS1 TCEA3 FAT4 FMNL3	3.74e-04	298	216	9	EFO_0005055
Disease	Alzheimer disease, dementia, family history of Alzheimer’s disease	EML6 HNRNPLL FMNL3 POLR3B	4.22e-04	48	216	4	EFO_0009268, MONDO_0001627, MONDO_0004975
Disease	Intellectual Disability	ZNF142 DISC1 SACS SCN1A CA2 AKAP6 SYNE1 SHANK3 POLR3B BBS7 ZNF335	4.92e-04	447	216	11	C3714756
Disease	malignant astrocytoma (is_marker_for)	ATRX ADGRB1 AKT1	6.15e-04	23	216	3	DOID:3069 (is_marker_for)
Disease	retinitis pigmentosa	DNAJC10 EYS	7.85e-04	6	216	2	MONDO_0019200
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	PTPRJ SMARCA4 CDH1	8.88e-04	26	216	3	C0009405
Disease	Colorectal cancer	PTPN12 PTPRJ AKT1	9.94e-04	27	216	3	cv:C0346629
Disease	Neoplasm of the large intestine	PTPN12 PTPRJ AKT1	9.94e-04	27	216	3	cv:C0009404
Disease	COLORECTAL CANCER	PTPN12 PTPRJ AKT1	9.94e-04	27	216	3	114500
Disease	Hereditary non-polyposis colorectal cancer syndrome	PTPRJ SMARCA4 CDH1	9.94e-04	27	216	3	C1112155
Disease	Colorectal Neoplasms	ABCA12 IPP FAT1 AKT1 SYNE1 STRAP CDH1 CDH5	1.05e-03	277	216	8	C0009404
Disease	Ovarian neoplasm	AKT1 CDH1	1.09e-03	7	216	2	cv:C0919267
Disease	Helicobacter Infections	PTPRZ1 CDH1	1.09e-03	7	216	2	C0079487
Disease	lung small cell carcinoma (is_implicated_in)	ATRX FAT1 LAMC2	1.11e-03	28	216	3	DOID:5409 (is_implicated_in)
Disease	PR interval	MYCBP2 ABCA12 SPTBN1 BMPR2 FAT1 HFM1 CAMTA1 TBX20 AKAP6 FNDC3B KALRN	1.13e-03	495	216	11	EFO_0004462
Disease	Hereditary Nonpolyposis Colorectal Cancer	PTPRJ SMARCA4 CDH1	1.23e-03	29	216	3	C1333990
Disease	Mental Retardation, X-Linked	ATRX PCDH19 FGD1	1.23e-03	29	216	3	C1136249
Disease	Ovarian Carcinoma	AKT1 SMARCA4 CDH1	1.36e-03	30	216	3	C0029925
Disease	pulmonary hypertension (is_implicated_in)	BMPR2 NOS3 IL23R	1.36e-03	30	216	3	DOID:6432 (is_implicated_in)
Disease	asthma	HLA-DPA1 SPEF2 PSMD3 FMNL2 SUOX MROH7 TASOR SEMG2 WDR36 SOCS3 GRM3 CDK5RAP2 ZNF76 UNC13C	1.36e-03	751	216	14	MONDO_0004979
Disease	memory impairment	FAT4 SHANK3	1.45e-03	8	216	2	EFO_0001072
Disease	schizophrenia (implicated_via_orthology)	NRG1 DISC1 AKT1 SHANK3	1.58e-03	68	216	4	DOID:5419 (implicated_via_orthology)
Disease	retinal degeneration (implicated_via_orthology)	NOS3 DCTN2 EYS	1.79e-03	33	216	3	DOID:8466 (implicated_via_orthology)
Disease	Colon Carcinoma	PTPN12 PTPRJ	1.86e-03	9	216	2	C0699790
Disease	electrocardiography	NRG1 MYCBP2 HLA-DPA1 SPTBN1 PTPN12 RNF10 TBX20 COG5 TCEA3 FNDC3B FMNL3	1.93e-03	530	216	11	EFO_0004327
Disease	colorectal cancer (is_implicated_in)	SEPTIN9 FAT1 PTPN12 PTPRJ AKT1	2.01e-03	121	216	5	DOID:9256 (is_implicated_in)
Disease	placenta growth factor measurement	RAPGEF5 FLT1	2.81e-03	11	216	2	EFO_0010626
Disease	corpus callosum anterior volume measurement	NAV3 LAMC2 FAM171B	2.91e-03	39	216	3	EFO_0010295
Disease	refractive error, age at onset, Myopia	TDRD9 AKAP6 FNDC3B FLT1 GRM3 B4GALNT2	3.07e-03	193	216	6	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Epilepsy, Cryptogenic	SCN1A PCDH19 AKT1 ASXL3	3.13e-03	82	216	4	C0086237
Disease	Awakening Epilepsy	SCN1A PCDH19 AKT1 ASXL3	3.13e-03	82	216	4	C0751111
Disease	Cardiomegaly	MFN2 AKT1 TBX20 NOS3	3.13e-03	82	216	4	C0018800
Disease	Aura	SCN1A PCDH19 AKT1 ASXL3	3.13e-03	82	216	4	C0236018
Disease	Cardiac Hypertrophy	MFN2 AKT1 TBX20 NOS3	3.13e-03	82	216	4	C1383860
Disease	invasive ductal carcinoma (is_marker_for)	ADGRB1 FGD1 SOCS3	3.13e-03	40	216	3	DOID:3008 (is_marker_for)
Disease	thyroid gland carcinoma (is_marker_for)	FLT1 CDH5	3.35e-03	12	216	2	DOID:3963 (is_marker_for)
Disease	oncostatin-M measurement	PSMD3 MED16	3.35e-03	12	216	2	EFO_0010792
Disease	Secondary Open Angle Glaucoma	FNDC3B WDR36	3.35e-03	12	216	2	C0271148
Disease	Glaucoma, Open-Angle	FNDC3B WDR36	3.35e-03	12	216	2	C0017612
Disease	neuropsychological test	FAM91A1 FAT4 FLT1 POLR3B UNC13C DSEL	3.39e-03	197	216	6	EFO_0003926
Disease	Antihypertensive use measurement	SEPTIN9 ETFDH GMDS NOS3 GLCE SORCS3 CDH16	3.51e-03	265	216	7	EFO_0009927
Disease	Charcot-Marie-Tooth disease	MCM3AP MFN2 DCTN2	3.60e-03	42	216	3	cv:C0007959
Disease	Profound Mental Retardation	DISC1 SCN1A SHANK3 POLR3B BBS7	3.65e-03	139	216	5	C0020796
Disease	Mental deficiency	DISC1 SCN1A SHANK3 POLR3B BBS7	3.65e-03	139	216	5	C0917816
Disease	Mental Retardation, Psychosocial	DISC1 SCN1A SHANK3 POLR3B BBS7	3.65e-03	139	216	5	C0025363
Disease	peak expiratory flow	SRPK2 GMDS TBX20 FNDC3B FREM3 EYS BBS7 GLCE ZNF76 CCDC171	3.87e-03	498	216	10	EFO_0009718
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A PCDH19	3.95e-03	13	216	2	C0751122
Disease	Glaucoma, Primary Open Angle	FNDC3B WDR36	3.95e-03	13	216	2	C0339573
Disease	cognitive impairment measurement	ADGRB3 NAV3 CDH5	4.11e-03	44	216	3	EFO_0007998
Disease	Malignant neoplasm of salivary gland	FAT1 VCAN CDH1	4.38e-03	45	216	3	C0220636
Disease	emphysema imaging measurement	NRG1 MYCBP2 HSP90AA4P IFT74 UNC13C	4.50e-03	146	216	5	EFO_0007626
Disease	reticulocyte count	SEPTIN9 EML6 FAT1 KCNU1 PTPRJ RNF10 GMDS PLS1 FNDC3B ANK1 MED16 CCDC92 PRPF8 WDSUB1 CDH1 CDH5	4.54e-03	1045	216	16	EFO_0007986
Disease	Salivary Gland Neoplasms	FAT1 VCAN CDH1	4.95e-03	47	216	3	C0036095
Disease	age at onset, Myopia	ZSCAN12 DEF8 AP1M1 AKAP6 FLT1	5.04e-03	150	216	5	EFO_0004847, HP_0000545
Disease	obesity (implicated_via_orthology)	PCSK1 DCHS2 LPIN1 GNA11 FAT4 WDTC1	5.18e-03	215	216	6	DOID:9970 (implicated_via_orthology)
Disease	Autosomal recessive primary microcephaly	ZNF335 CDK5RAP2	5.26e-03	15	216	2	cv:C3711387
Disease	sleep duration	ZSCAN12 MYCBP2 RAPGEF5 PTPRJ SCN1A CAMTA1 COG5 ANK1	5.42e-03	362	216	8	EFO_0005271
Disease	Pain, Crushing	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0458259
Disease	Pain, Splitting	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0458257
Disease	Pain	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0030193
Disease	Pain, Migratory	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0751407
Disease	Suffering, Physical	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0751408
Disease	Radiating pain	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0234254
Disease	Pain, Burning	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0234230
Disease	Ache	NRG1 DISC1 AKT1	5.56e-03	49	216	3	C0234238
Disease	Mammary Carcinoma, Human	NRG1 CENPF ADAM10 BMPR2 AKT1 NOS3 FLT1 SYNE1 CDH1 CDH5	5.57e-03	525	216	10	C4704874
Disease	Mammary Neoplasms, Human	NRG1 CENPF ADAM10 BMPR2 AKT1 NOS3 FLT1 SYNE1 CDH1 CDH5	5.57e-03	525	216	10	C1257931
Disease	glaucoma	RAPGEF5 FMNL2 GMDS FNDC3B KALRN	5.62e-03	154	216	5	MONDO_0005041
Disease	Mammary Neoplasms	NRG1 CENPF ADAM10 BMPR2 AKT1 NOS3 FLT1 SYNE1 CDH1 CDH5	5.72e-03	527	216	10	C1458155
Disease	shigellosis	IL23R MPP7	5.98e-03	16	216	2	EFO_0005585
Disease	T-Cell Lymphoma	AKT1 ASXL3	5.98e-03	16	216	2	C0079772
Disease	Pre-Eclampsia	NOS3 FLT1	5.98e-03	16	216	2	C0032914
Disease	nervousness	ETFDH PTPRJ	5.98e-03	16	216	2	NCIT_C74532
Disease	periodontitis	MCM3AP CAMTA1 HSP90AA4P AKAP6 WDR36 FMNL3	6.17e-03	223	216	6	EFO_0000649
Disease	urate measurement, bone density	ADGRB3 VWA3B DNAH8 MPP7 AKAP6 SYNE1 CCDC92 MINPP1 THAP9 EYS PEAK1	6.19e-03	619	216	11	EFO_0003923, EFO_0004531
Disease	epithelial cell adhesion molecule measurement	TPP2 EML6 PPP4R3B	6.22e-03	51	216	3	EFO_0010574
Disease	free cholesterol to total lipids in small HDL percentage	ETFDH ADAM10 SMARCA4	6.22e-03	51	216	3	EFO_0022285
Disease	Adenoid Cystic Carcinoma	ATRX FAT1 VCAN CDH1	6.33e-03	100	216	4	C0010606
Disease	gastroesophageal reflux disease	SNRK NAV3 VCAN SORCS3	6.56e-03	101	216	4	EFO_0003948
Disease	Breast Carcinoma	NRG1 CENPF ADAM10 BMPR2 AKT1 NOS3 FLT1 SYNE1 CDH1 CDH5	6.58e-03	538	216	10	C0678222
Disease	low density lipoprotein cholesterol measurement, body fat percentage	EFCAB13 CCDC92	6.75e-03	17	216	2	EFO_0004611, EFO_0007800
Disease	major depressive disorder (is_marker_for)	NRG1 DISC1	6.75e-03	17	216	2	DOID:1470 (is_marker_for)
Disease	Cannabis Dependence	NRG1 AKT1	6.75e-03	17	216	2	C0006870
Disease	Kuhnt-Junius degeneration (is_implicated_in)	NOS3 FLT1	6.75e-03	17	216	2	DOID:10873 (is_implicated_in)
Disease	Uremia	NOS3 FLT1	6.75e-03	17	216	2	C0041948
Disease	Bell's palsy	DISC1 DNAH8 MGAT4C FNDC3B	6.79e-03	102	216	4	EFO_0007167
Disease	neutrophil percentage of granulocytes	SPEF2 PSMD3 SUOX WDR36 BATF RFX6	6.85e-03	228	216	6	EFO_0007994

Protein segments in the cluster

Peptide	Gene	Start	Entry
VTHTVQKVEAVQTSY	UMODL1	41	Q5DID0
ALYTHNKEVASAVSA	ACCSL	406	Q4AC99
AEITYTSKHSVEVQV	ACOT7	126	O00154
EIVSALDYLHSEKNV	AKT1	256	P31749
VSAEITYTSKHSVEV	ACOT7L	46	Q6ZUV0
EYTTEVHSKELTNVF	BDP1	2396	A6H8Y1
LNISYEINEVSVKHT	BBS7	591	Q8IWZ6
TEKESALATAQQYLH	AVIL	666	O75366
TNEEIAAYLITFEKH	CAMTA1	76	Q9Y6Y1
ETAIRALETYQSHKN	ELL2	36	O00472
HSKSVKVQERYDSAV	ANKRD10	396	Q9NXR5
ETTHEKIQAAEYGLV	BICD1	26	Q96G01
KEEVLQSTTGVSHYA	VCAN	456	P13611
TTKYDENITTVLLAH	VCAN	776	P13611
STGYQHQKVDIVSLE	B4GALNT2	276	Q8NHY0
DAYQVTDNLVLSIHK	ADGRB1	761	O14514
HYTTINVLDTEAKDA	ADGRB3	1481	O60242
EVAAYLTEKAHSVSV	AIFM3	346	Q96NN9
ISSHVKAIDTIYQTT	ADAM10	246	O14672
SATFEHLVYKINSNE	ADAM21	151	Q9UKJ8
DEHYLLATQSKQEQS	ACTR8	421	Q9H981
TASFVTYVVREHQTK	ABCA12	2001	Q86UK0
GSQEYEKVLVSVSEH	ANK1	1746	P16157
EITTKHNAELASYES	CCDC171	51	Q6TFL3
HLAIDSSNYEQESKI	GRM3	376	Q14832
SQATVHITVTEENYH	FAT4	3071	Q6V0I7
TDSKILQEYITQEGH	AP1M1	126	Q9BXS5
NKQVVEASYTAHLTS	CACHD1	106	Q5VU97
AIKADHVSTYAAFVQ	HLA-DPA1	31	P20036
ETTEKNQLFTIHYVS	GLCE	311	O94923
TTYITVLVKDTNDHS	CELSR1	336	Q9NYQ6
EDADTQSKVHQLYET	DCTN2	301	Q13561
HPVEVVYLSEAQKDS	DHX32	241	Q7L7V1
ENISEYHLTAVIVDK	CDH5	111	P33151
YHLTAVIVDKDTGEN	CDH5	116	P33151
LTDNHDNTANITVKY	CDH5	526	P33151
REVEHQETAYETSVK	DISC1	651	Q9NRI5
AIKTEHANYLNVSEL	ASXL3	1641	Q9C0F0
QDIYTHLVKSLQESD	CDK5RAP2	561	Q96SN8
EAKAETIQALYHQTL	MROH7	526	Q68CQ1
VNDTKHHLYSDINIT	NPFFR2	121	Q9Y5X5
DRLVTAKTESVQYDH	NOL12	86	Q9UGY1
SDAVKNESHVETTYL	RFX6	586	Q8HWS3
TQDALHTVEKYSFEE	IPP	496	Q9Y573
KTDAVEALTALNHYQ	HNRNPLL	506	Q8WVV9
IVSAHTQKTYEVNEV	GUF1	286	Q8N442
SKENIASVLENYHTE	HIBCH	236	Q6NVY1
QYVSKNVISSEHIVE	NRG1	311	Q02297
FVNASSKYEITTIHN	SERPIND1	186	P05546
TQRKEEESQSSSIYH	AOC2	631	O75106
VVEKSLDRETQSHYS	PCDH19	191	Q8TAB3
HLEYNVTVQENSAAK	FAT1	36	Q14517
QSSYEELKEISVVVH	MGAT4C	126	Q9UBM8
RVKLSVQTHSTDDYI	PTPRJ	1081	Q12913
EYQEAVSKSTFQHLV	IGDCC3	471	Q8IVU1
IIDSSRSVNTHDYAK	MATN2	61	O00339
VTLKTYSEITHANDF	EYS	1756	Q5T1H1
QSHVKISFDLAEYTA	GMDS	111	O60547
EQSVHQYTISKDEPL	NRAP	756	Q86VF7
KDITHSYLEQETTGI	MIPOL1	6	Q8TD10
ATYESVLFHQLQEIK	MTO1	611	Q9Y2Z2
YKIFVSIDEHTNVAE	FAM91A1	256	Q658Y4
QVDHAAAVKEYSRSS	MCM3AP	666	O60318
KHGVIISSTVDTYEN	F13B	531	P05160
TQHSYSEEEKVAFVN	PLS1	116	Q14651
KTTSVISHTYEEIET	PEAK1	656	Q9H792
DDVVLHVSSKTTLQY	NAV3	1121	Q8IVL0
VSDNINEVTFHAKDY	DNAH8	1611	Q96JB1
ADYISKNVPATDHVI	NRG2	471	O14511
ATANYSKAVHQVLDV	KALRN	496	O60229
ALLSVHDTVAQKNYD	MPP7	106	Q5T2T1
FYADDQSTHKQVLTL	MOSPD1	26	Q9UJG1
IQSYADQHKITIVDF	LRRC74A	416	Q0VAA2
ELVQEHAKTNISSYV	LPIN1	826	Q14693
LEVASDSYHKVASDV	LCT	426	P09848
HEYHAETIKNVRTAT	PKM	81	P14618
YEIVNKASQTTETHS	KCNU1	1056	A8MYU2
LHDASQDLVYETVAK	KIF9	61	Q9HAQ2
YQVFQKVTDHATTAL	MED27	236	Q6P2C8
KETEVLDSHIHAYVN	PTPRZ1	1996	P23471
EDIKSLTAHIVENFY	PPP4R3B	646	Q5MIZ7
EAEYVNSLASHKINV	DDX31	636	Q9H8H2
QYNTTIAHVTLDKDR	FOXRED2	141	Q8IWF2
AQTYHLKASSEVERQ	OSBP	156	P22059
NVEKTLSCLDHVISY	EXOC7	76	Q9UPT5
VTVHQSIGEAKEQFY	MDGA2	136	Q7Z553
VEHASEKLQLVISYT	MFN2	666	O95140
KHENIVTLEDIYEST	CAMK1G	76	Q96NX5
QSLVEKLHEEYTRQT	MED16	501	Q9Y2X0
DKAAVEINVAVLHSY	NOS3	396	P29474
SHAEIIYNIISGNEK	DCHS2	2696	Q6V1P9
ADNQVVYLHKITDSV	HFM1	1036	A2PYH4
KTYTSQSIHQAVIAE	COG5	76	Q9UP83
FQELDEHISYVATKV	EXOC5	96	O00471
ENLQSKTIGLHVTEY	ETFDH	421	Q16134
DTDINEIHTNHKTLY	ATRX	751	P46100
ATETHLNIYGQEAKV	CDHR2	321	Q9BYE9
YEALKTQLQENETHS	IFT74	526	Q96LB3
EVIFAVYHENTKSAS	C2CD3	1291	Q4AC94
VYHENTKSASDIISI	C2CD3	1296	Q4AC94
IKSYSIEDHIIKSNT	E2F8	221	A0AVK6
SKDYIVALQHPVTTD	GNE	211	Q9Y223
ESNSYEHLTLSDKEV	CENPF	1386	P49454
KENEVSEHTLESYRS	CRTAM	321	O95727
QQHCTDLTYELTVKS	CCDC92	56	Q53HC0
ENVTVPASAHKIEYS	FRS2	396	Q8WU20
SNSKTHAAEDIVYTL	FNDC3B	981	Q53EP0
AHYDAVEAELKSSTV	FAM50A	51	Q14320
ELESIKETYENTSHQ	FMNL3	436	Q8IVF7
TEELKYFTSVLNSHE	BATF	76	Q16520
VDVEKVTTFEHQYVS	GNA11	116	P29992
VTTFEHQYVSAIKTL	GNA11	121	P29992
VTSEFESYKVRVHNV	GCC2	1316	Q8IWJ2
HVKSLETEEEQQYLT	IL23R	161	Q5VWK5
YIEDSIHHTDSIVKN	BMPR2	551	Q13873
KNLDYVATSIHEAVT	GOT1	396	P17174
EVISTLHYFSKVVDE	APPL2	81	Q8NEU8
HYVEKAAAVSLENVL	FMNL2	886	Q96PY5
EEAAHTLTISIYDTK	DRC7	706	Q8IY82
EILEEVTKHTYIDSN	EFCAB13	256	Q8IY85
VSSKVSHQAEYELNI	DEF8	251	Q6ZN54
EYSVHKITSTFHQDV	LAMC2	201	Q13753
DSYTVQTISVLKDVH	EML5	91	Q05BV3
DSYNVQTVSLLKDVH	EML6	91	Q6ZMW3
QHITLSDEERKIYQS	HLTF	666	Q14527
AYSVAEKVTVITKHN	HSP90AA4P	81	Q58FG1
VSERYAHQQETSSKV	CCDC168	5756	Q8NDH2
YDILAFAKESVNSHV	DNAJC10	441	Q8IXB1
VTYHVNIVLEEESTK	SACS	371	Q9NZJ4
TEHVVSIVTDYHNLK	DSEL	711	Q8IZU8
INEDSKDITAYHTVF	FAM171B	341	Q6P995
KNLSYEAAPSHEVVV	CDH16	516	O75309
EDFEHVKNSTYTALI	CDH1	551	P12830
SHEESELANKLITVY	CEBPZ	451	Q03701
KYEHDDIVSTVSVLS	WDR77	121	Q9BQA1
KIEISTIASNYHLEV	RFC3	81	P40938
LIYASVSVHAAKQEE	APOOL	16	Q6UXV4
EEESVHVTQRKTHYS	ORC3	166	Q9UBD5
QHEETTYIAIALKSS	NRK	1321	Q7Z2Y5
AVTVHYIADKNATAT	NRAC	76	Q8N912
TLKEIQEASTIVYEH	FREM3	1256	P0C091
TDLKHYSDELQSVIS	SNX4	221	O95219
TDVARYHIETSTKIQ	SPEF2	1411	Q9C093
AARTKTYVQEHSVVD	PRELID3B	71	Q9Y3B1
KTTVYVSHINDLSDF	TDRD6	1306	O60522
REYLSEEVQAVHKNT	USP39	481	Q53GS9
EEVQAVHKNTTYDLI	USP39	486	Q53GS9
SLLEDTTSAYQEHEK	SYNE1	4771	Q8NF91
ETKSVTEVDTLALHY	TMEM161B	86	Q8NDZ6
KVSDSISAQYPVVDH	SDHA	46	P31040
LTEESYESKQSHEVL	TDRD9	1086	Q8NDG6
YQDSTIKDLSHEVTR	FER1L5	481	A0AVI2
VHVVISSDSLADKNY	HPS3	841	Q969F9
YLEDVAKNETSATHQ	LMBRD2	336	Q68DH5
TKEIAVHEYFQSQLL	SORCS3	991	Q9UPU3
VTQEDAGSYTLHIIK	PSG6	111	Q00889
QTITEYDEHLTQLEK	TAF1L	1621	Q8IZX4
QEAEHITSVYLQLKA	ODAD3	221	A5D8V7
TSDYVTVHSDVERKK	OVCH2	486	Q7RTZ1
NQTVVVEYTHDKDTD	PELI2	86	Q9HAT8
HIANELLQTEKAYVS	FGD1	376	P98174
TQRHSAVQTKEQYEL	PTPN12	271	Q05209
SCIYVNKITHEVDEL	POLR2I	51	P36954
TKAVATYHANTEREQ	SMARCA4	501	P51532
QNIKDITSSIHFEAY	SEPTIN9	546	Q9UHD8
EHSYVSVKAKVSSIA	RAPGEF5	251	Q92565
VQVKAAFNEETHSYE	SETD4	241	Q9NVD3
TLTIHNVEKQDIATY	TRGV9	101	Q99603
ENRITKTVSHLYQES	TANC1	1816	Q9C0D5
YKQESSESHNIVITE	SEMG2	546	Q02383
TITVQTKDQYGDVVH	MYCBP2	2286	O75592
DEYLINSQTTEHIVK	IARS2	541	Q9NSE4
DIVNKEDIYSHLTSV	MROH2B	26	Q7Z745
SYKNLSEEEHNSIIQ	SNRK	286	Q9NRH2
TVYSIFSKVHSDRNV	SGCE	36	O43556
HIVKTVDFTQDSNYL	STRAP	101	Q9Y3F4
KGVQIHTSVVDSDYK	ERVK-9	711	P63128
HTSVVDSDYKGEIQL	ERVK-9	716	P63128
SLEEHSIEKNITVNY	SCN1A	286	P35498
VEDYAETVHQLSKTS	SPTBN1	1641	Q01082
EAAHSEILKYFQSVT	STX5	316	Q13190
SAINFHSVVEKYVSE	TASOR	546	Q9UK61
HVASTVQTYSAIEEA	ABTB1	446	Q969K4
DLTYSVQQDSDSKHV	AKAP6	86	Q13023
ERQSPVDIDTHTAKY	CA2	26	P00918
ATETVSHKALDADIY	C12orf29	36	Q8N999
TDEIRQSDYITEKHS	C12orf40	251	Q86WS4
EVKHVHLENATEYAT	C11orf52	91	Q96A22
DDTNVYRVTIHKTFE	PRPF8	1781	Q6P2Q9
RTNHIYVSSDDIKET	PRPF8	2086	Q6P2Q9
ENSKHSEVLIDLTEY	WDTC1	166	Q8N5D0
DYKTVIFENLSQHIA	ZNF639	266	Q9UID6
VIEASINHEKGYVQS	PSMD3	446	O43242
ESDILEKQTTTHYAD	UNC13C	516	Q8NB66
SLYHVESTVNSELKA	MIOS	26	Q9NXC5
LTEVEKNATALYHVE	MINPP1	236	Q9UNW1
SNKNASEHIVYLLEV	RLF	86	Q13129
TVIYKNQDLSQATDH	SPEM3	816	A0A1B0GUW6
SHSDYVIDDKVAVLQ	SHANK3	561	Q9BYB0
SQEVATEDHNYSLKT	THAP9	116	Q9H5L6
VSEDSSVTQIYHAVA	RPN2	116	P04844
TYIAKVDGEISASHV	ROPN1	166	Q9HAT0
KSVVATESHQYVVGD	RNF10	276	Q8N5U6
DHTEEVSNLVNYVLK	SUN3	161	Q8TAQ9
SEENVKIIENHFTTY	THAP5	376	Q7Z6K1
VVKSAQHYTETALDE	SRPK2	111	P78362
ITAVIAAKVNESSHY	TPP2	631	P29144
TEYVKTQLQLDERSH	SLC25A1	46	P53007
SGYVKSLAVHVAETE	NUP188	1076	Q5SRE5
AIETLIKNFHQYSVE	S100A14	21	Q9HCY8
TVNGHLDSYEKVTQL	SOCS3	196	O14543
QVTENTTEKAATYHV	SERPINB4	61	P48594
VDLYQEVSLSHKDNI	SERPINI2	31	O75830
YEHTINKDTTHLEIE	POLR3B	646	Q9NW08
ASEIEDHIYQELKST	TCEA3	216	O75764
VATEDDFYTSHNLVK	PKHD1L1	3946	Q86WI1
SEKYNHAITEVINTV	SMCO3	206	A2RU48
KVYTDVQQVASSLTH	TTLL12	306	Q14166
KQSETSIHQYLVDEP	STRADB	21	Q9C0K7
AVTNLYKESVDTHQR	TAPR1	96	Q14CZ0
RAAQESTHIYTKEEV	SUOX	76	P51687
ERESVESLIQKHSYA	TBX20	296	Q9UMR3
VKHYLEQHEETSAAV	ZNF142	1396	P52746
KSELIYQFVEHLTQA	VWA3B	101	Q502W6
KSVIVYDTNTENILH	WDSUB1	261	Q8N9V3
VDSTDRVYFVNHNTK	WWP1	466	Q9H0M0
SVNTSVHIYDKAFIT	FLT1	321	P17948
AVVVSDTLKEAGTHY	ZNF335	911	Q9H4Z2
KAFVYNSSLVSHQEI	ZSCAN12	421	O43309
ISAEKAYHEQLTVAE	TUBA1C	276	Q9BQE3
YQTSQERVVDKHESV	USP6	1006	P35125
TAYIHQVTVQKEALS	ZNF76	41	P36508
VALEQYASKVLHDSQ	ZNF76	136	P36508
HFESKLSDTIEVYQE	VWA3A	136	A6NCI4
FHTYDVQKLSLVAVS	WDR36	106	Q8NI36
AHYDAVEAELKSSTV	FAM50B	51	Q9Y247
IKSLEHVQFEATIEY	PCSK1	501	P29120