Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
PathwayREACTOME_SIGNALING_BY_FLT3_FUSION_PROTEINS

SPTBN1 TRIP11 STAT5A PIK3R1

4.05e-0619834M41732
PathwayREACTOME_FLT3_SIGNALING_IN_DISEASE

SPTBN1 TRIP11 STAT5A PIK3R1

2.05e-0528834M41724
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DPYSL3 ARHGEF28 AFTPH RBBP7 SPTBN1 CCDC18 CEP192 TRIP11 PTPN13 MDN1 TIAM1 STARD9 PI4KA TNFAIP3 NOTCH2

2.42e-078611181536931259
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GABRD ABHD14A DCHS2 HSP90B1 RELN SUPT20H SPTBN1 APC2 ZNF343 TRIP11 MAPK8IP3 NELL1 MFGE8 PTPN13 TIAM1 PIK3R1 PADI2 ZMYM5

3.48e-0712851181835914814
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

HSP90B1 DNAJC13 AFTPH SPTBN1 CCDC18 SHMT1 CHD1 CEP192 TRIM24 THADA PTPN13 KIDINS220 MDN1 TIAM1 PIK3R1 PI4KA NUP133 ADGRL2 NOTCH2

6.37e-0714871181933957083
Pubmed

Normal immune system development in mice lacking the Deltex-1 RING finger domain.

DTX1 DTX4

1.14e-052118215684394
Pubmed

A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo.

THRB PIK3R1

1.14e-052118224932806
Pubmed

Regulation of CD23 expression by Notch2 in B-cell chronic lymphocytic leukemia.

FCER2 NOTCH2

1.14e-052118215621797
Pubmed

Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency.

NFIL3 NCR1

1.14e-052118230234375
Pubmed

Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens.

NFIL3 NCR1

1.14e-052118225113970
Pubmed

Agonist-induced association of the p21ras GTPase-activating protein with phosphatidylinositol 3-kinase.

RASA1 PIK3R1

1.14e-05211821336372
Pubmed

Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias.

STAT5A PIK3R1

1.14e-052118217038539
Pubmed

Effects of LAR and PTP-BL phosphatase deficiency on adult mouse retinal cells activated by lens injury.

PTPN13 PTPRF

1.14e-052118215932596
Pubmed

Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.

FCER2 NOTCH2

1.14e-052118215565166
Pubmed

CapG promotes resistance to paclitaxel in breast cancer through transactivation of PIK3R1/P50.

CAPG PIK3R1

1.14e-052118231660072
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

HSP90B1 DPYSL3 DNAJC13 SPTBN1 CCDC18 CEP192 PTPN13 PTPRF TIAM1 PIK3R1 PI4KA NUP133 UNG ADGRL2

1.34e-0510491181427880917
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

DNAJC13 APOB CEP192 TRIP11 THADA PTPN13 KIDINS220 ZBED6 PI4KA ZFHX3 ADGRL2 NOTCH2

1.40e-057771181235844135
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

PRUNE2 AFTPH PPFIBP2 DTX1 APC2 TNRC18 PIK3R1 WDR90 ZMYM5

1.69e-05430118935044719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EML2 CEP192 CFAP43 ABCA7 MAPK8IP3 THADA TNRC18 MDN1 PTPRF DOK4 PI4KA WDR90 TNFAIP3 NOTCH2

2.38e-0511051181435748872
Pubmed

SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women.

APOB PIK3R1

3.42e-053118217214991
Pubmed

Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development.

DTX1 NOTCH2

3.42e-053118212753744
Pubmed

T cells develop normally in the absence of both Deltex1 and Deltex2.

DTX1 DTX4

3.42e-053118216923970
Pubmed

Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.

RASA1 PIK3R1

3.42e-05311821314164
Pubmed

PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice.

APOB PIK3R1

3.42e-053118216798720
Pubmed

Cyclic mechanical stretch decreases cell migration by inhibiting phosphatidylinositol 3-kinase- and focal adhesion kinase-mediated JNK1 activation.

MAPK8IP3 TIAM1

3.42e-053118220018857
Pubmed

GM1 inhibits early signaling events mediated by PDGF receptor in cultured human glioma cells.

RASA1 PIK3R1

3.42e-053118210697503
Pubmed

RNF144B stimulates the proliferation and inhibits the apoptosis of human spermatogonial stem cells via the FCER2/NOTCH2/HES1 pathway and its abnormality is associated with azoospermia.

FCER2 NOTCH2

3.42e-053118235699595
Pubmed

Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling.

THRB PIK3R1

3.42e-053118217606624
Pubmed

Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.

STAT5A IRF9 PIK3R1

3.55e-0519118332075740
Pubmed

Genomic analysis of mouse retinal development.

ABHD14A DPYSL3 ZNF595 IRF9 OSBP NRXN2 PIK3C2G PIK3R1 DTX4 SORCS2 IGSF9 TNFAIP3 GOT2

3.88e-0510061181315226823
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 DNAJC13 RASA1 PPFIBP2 CEP192 ZNF595 MAPK8IP3 THADA TNRC18 PTPN13 KIDINS220 THRB TECPR2 IGSF9 ZFHX3 NOTCH2

4.46e-0514891181628611215
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SPTBN1 TRIP11 GPATCH2L AKTIP NFIL3 ITGB1BP2 NUP133 PYGM NOTCH2

5.22e-05497118923414517
Pubmed

Association of T cell antigen CD7 with type II phosphatidylinositol-4 kinase, a key component in pathways of inositol phosphate turnover.

PIK3R1 PI4KA

6.82e-054118212594831
Pubmed

Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane.

DTX1 NOTCH2

6.82e-05411829244302
Pubmed

Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein.

RASA1 PIK3R1

6.82e-05411827642582
Pubmed

The AAA ATPase MDN1 Acts as a SUMO-Targeted Regulator in Mammalian Pre-ribosome Remodeling.

MDN1 PELP1

6.82e-054118227814492
Pubmed

Tyrosine 785 is a major determinant of Trk--substrate interaction.

RASA1 PIK3R1

6.82e-05411828384556
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

HSP90B1 DPYSL3 DNAJC13 RBBP7 SPTBN1 TRIP11 MAPK8IP3 KIDINS220 TENM4 NRXN2 CAMKV PI4KA SORCS2 KNG1 GOT2

1.04e-0414311181537142655
Pubmed

Type I Interferons Ameliorate Zinc Intoxication of Candida glabrata by Macrophages and Promote Fungal Immune Evasion.

STAT5A IRF9 PIK3R1

1.05e-0427118332428860
Pubmed

Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain.

ABCC9 PIK3C2G

1.13e-04511829514948
Pubmed

Sam68 from an immortalised B-cell line associates with a subset of SH3 domains.

RASA1 PIK3R1

1.13e-04511828766817
Pubmed

Heat shock protein gp96 drives natural killer cell maturation and anti-tumor immunity by counteracting Trim28 to stabilize Eomes.

HSP90B1 NCR1

1.13e-045118238321029
Pubmed

Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling.

RASA1 PIK3R1

1.13e-045118211604231
Pubmed

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.

PIK3R1 PI4KA

1.13e-04511828246987
Pubmed

The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF.

TNFAIP3 NCR1

1.13e-045118231296735
Pubmed

Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling.

RASA1 PIK3R1

1.13e-045118212112020
Pubmed

ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.

FCER2 NOTCH2

1.13e-045118220156974
Pubmed

Identification of residues in the beta platelet-derived growth factor receptor that confer specificity for binding to phospholipase C-gamma 1.

RASA1 PIK3R1

1.13e-04511827689724
Pubmed

Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis.

NFIL3 NCR1

1.13e-045118234183415
Pubmed

Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants.

RASA1 PIK3R1

1.13e-04511828321198
Pubmed

Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.

ARHGEF28 FARS2 PIK3R1

1.45e-0430118338310234
Pubmed

Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells.

NFIL3 NCR1

1.70e-046118231586012
Pubmed

Testing the association of novel meta-analysis-derived diabetes risk genes with type II diabetes and related metabolic traits in Asian Indian Sikhs.

THADA NOTCH2

1.70e-046118219247373
Pubmed

Multiple molecular chaperones interact with apolipoprotein B during its maturation. The network of endoplasmic reticulum-resident chaperones (ERp72, GRP94, calreticulin, and BiP) interacts with apolipoprotein b regardless of its lipidation state.

HSP90B1 APOB

1.70e-04611829694898
Pubmed

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.

RELN NOTCH2

1.70e-046118218957219
Pubmed

Nfil3-independent lineage maintenance and antiviral response of natural killer cells.

NFIL3 NCR1

1.70e-046118224277151
Pubmed

Proline-rich motifs of the Na+/H+ exchanger 2 isoform. Binding of Src homology domain 3 and role in apical targeting in epithelia.

RASA1 PIK3R1

1.70e-046118210187839
Pubmed

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

THADA NOTCH2

1.70e-046118218567820
Pubmed

Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity.

NFIL3 NCR1

1.70e-046118229915296
Pubmed

Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.

STAT5A GJA10

1.70e-046118220966351
Pubmed

Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.

DTX1 NOTCH2

1.70e-046118211731257
Pubmed

JAK-STAT and JAK-PI3K-mTORC1 pathways regulate telomerase transcriptionally and posttranslationally in ATL cells.

STAT5A PIK3R1

1.70e-046118222402124
Pubmed

Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo.

RASA1 PIK3R1

1.70e-04611828084603
Pubmed

Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands.

NFIL3 NCR1

1.70e-046118227156386
Pubmed

Interaction of constitutive photomorphogenesis 1 protein with protein-tyrosine phosphatase 1B suppresses protein-tyrosine phosphatase 1B activity and enhances insulin signaling.

COP1 PIK3R1

1.70e-046118223439647
Pubmed

An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia.

PIK3C2G PI4KA

1.70e-046118217893707
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PTGFRN TENM4 STARD9 SORCS2 IGSF9

1.81e-04153118510718198
Pubmed

Sporadic Hirschsprung Disease: Mutational Spectrum and Novel Candidate Genes Revealed by Next-generation Sequencing.

PTPN13 ZFHX3

2.37e-047118229093530
Pubmed

A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype.

RELN TRIP11

2.37e-047118221214893
Pubmed

Localization of 11q13 loci with respect to regional chromosomal breakpoints.

OSBP PYGM

2.37e-04711821572647
Pubmed

Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth.

RELN PIK3R1

2.37e-047118217698586
Pubmed

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication.

PIK3C2G PI4KA

2.37e-047118219376974
Pubmed

The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex.

MDN1 PELP1

2.37e-047118221326211
Pubmed

Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells.

PIK3R1 PI4KA

2.37e-047118217242350
Pubmed

Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.

CHD1 TIAM1

2.37e-047118222044751
Pubmed

A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.

RASA1 PIK3R1

2.37e-04711821383690
Pubmed

Nascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin B.

HSP90B1 APOB

2.37e-047118212397072
Pubmed

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.

PTPRF PIK3R1

2.37e-047118210660596
Pubmed

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.

HSP90B1 DNAJC13 KIDINS220 PI4KA

2.46e-0489118427034005
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

HSP90B1 TRIM24 MDN1 PTPRF PELP1 ZMYM5

2.81e-04262118636880596
Pubmed

Functional interaction between c-Src and its mitotic target, Sam 68.

RASA1 PIK3R1

3.15e-04811827537265
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRF NRXN2

3.15e-048118237591863
Pubmed

High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism.

RASA1 NOTCH2

3.15e-048118215068794
Pubmed

Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection.

IRF9 NCR1

3.15e-048118230134157
Pubmed

Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5.

RASA1 DOK4

3.15e-048118212730241
Pubmed

Guanosine triphosphatase-activating protein-associated protein, but not src-associated protein p68 in mitosis, is a part of insulin signaling complexes.

RASA1 PIK3R1

3.15e-04811829564850
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

B3GNT5 CAPG SPTBN1 SHMT1 APOB CEP192 ZNF595 GPATCH2L PTPN13 PIK3R1 PI4KA TNFAIP3

3.26e-0410841181211544199
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DNAJC13 TRIP11 PTPN13 KIDINS220 PIK3R1 PI4KA ADGRL2 NOTCH2

3.35e-04504118834432599
Pubmed

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.

DTX1 NOTCH2

4.05e-049118217573339
Pubmed

A systematic scan of interactions with tyrosine motifs in the erythropoietin receptor using a mammalian 2-hybrid approach.

STAT5A PIK3R1

4.05e-049118215644415
Pubmed

The Metabolic Reprogramming of Frem2 Mutant Mice Embryos in Cryptophthalmos Development.

ABCC9 STAT5A

4.05e-049118233490088
Pubmed

Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

THADA NOTCH2

4.05e-049118218714373
Pubmed

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.

PIK3C2G PIK3R1

5.05e-041011828798481
Pubmed

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.

PIK3C2G PIK3R1

5.05e-041011829247029
Pubmed

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

NRXN2 PYGM

5.05e-0410118221768215
Pubmed

c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice.

STAT5A NCR1

5.05e-0410118232103006
Pubmed

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

PIK3C2G PIK3R1

5.05e-041011828636073
Pubmed

JAK-STAT signaling maintains homeostasis in T cells and macrophages.

STAT5A IRF9

5.05e-0410118238658806
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM4 ADGRL2

5.05e-0410118238713721
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

ABHD14A ZNF567 B3GNT5 COL20A1 RBBP7 STAT5A AKTIP PELP1 PIK3R1 PI4KA

5.55e-048321181036724073
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TRIP11 PTPN13 KIDINS220 PIK3R1 PI4KA ADGRL2 NOTCH2

6.04e-04421118736976175
Pubmed

Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.

RASA1 PIK3R1

6.15e-0411118220598684
Cytoband16q21

DRC7 DOK4 GOT2

2.17e-0445118316q21
CoexpressionBASSO_CD40_SIGNALING_UP

HSP90B1 CAPG CHD1 STAT5A IRF9 TNFAIP3

6.65e-061031166M8493
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 DCHS2 GPATCH2L MDN1 SASS6 PYGM TDP1

6.41e-08132118746c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCellLPS-IL1RA+antiTNF-Unknown|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 DCHS2 GPATCH2L MDN1 SASS6 PYGM TDP1

6.41e-081321187a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 DCHS2 RELN ARHGEF28 TENM4 THRB PKHD1

4.91e-071781187544379f5a6145429762258d426b876bb36c112f5
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 DPYSL3 RELN DTX1 PTGFRN PTPRF ZFHX3

8.17e-071921187b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 DPYSL3 RELN DTX1 PTGFRN PTPRF ZFHX3

8.17e-071921187ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTX1 ZNF689 CAPG FCER2 DOK4 SESN2

6.19e-0617011866210ee3bf29059e6149c047bb7e02c5f59441519
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 KL PIK3C2G PIK3R1 PKHD1 KNG1

6.84e-0617311860c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 DCDC1 CFAP43 LRRC53 WDR90 PZP

8.58e-06180118692fb01b91261b3103454924cde56add337b41844
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

RELN DTX1 ITGB1BP2 SORCS2 PYGM PADI2

8.85e-061811186f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC9 ISLR ZNF112 THADA PTPRF SORCS2

1.20e-051911186b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 PPFIBP2 ABCC9 MFGE8 ZFHX3 PZP

1.20e-0519111867853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SPTBN1 ABCC9 PTGFRN NRXN2 FAM180A

1.27e-0519311862483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

DPYSL3 CHD1 TIAM1 NFIL3 ZFHX3 TNFAIP3

1.27e-0519311867426c291bac59e539c427bcaae18abc7d397d44e
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGEF28 TRIM24 PTPN13 PTPRF LTA4H PADI2

1.43e-0519711861485933986921ff45669d9b7501c8d17050b3e97
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGEF28 TRIM24 PTPN13 PTPRF DOK4 LTA4H

1.47e-051981186d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

DPYSL3 APC2 KIDINS220 NRXN2 CAMKV ZFHX3

1.47e-051981186b73b9feb82997b654718aa27f33ca7b454214802
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ARHGEF28 PTPN13 PTPRF DOK4 LTA4H PADI2

1.47e-051981186aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CCDC18 CHD1 TRIM24 TRIP11 PTPN13 TNFAIP3

1.47e-05198118676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ARHGEF28 TRIM24 PTPN13 PTPRF LTA4H PADI2

1.56e-052001186e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 ABCC9 MFGE8 PIK3R1 ZFHX3 PZP

1.56e-052001186f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 ABCC9 MFGE8 PIK3R1 ZFHX3 PZP

1.56e-05200118667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellControl_saline-Endothelial-Endothelial-Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

DPYSL3 SPTBN1 KL KIDINS220 ADGRL2 PZP

1.56e-052001186abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 KL PIK3C2G ADGRL2 KNG1

3.58e-0514011855e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 MFGE8 ZBED6 ITGB1BP2 ZFHX3

5.30e-0515211850cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 MFGE8 ZBED6 ITGB1BP2 ZFHX3

5.30e-051521185ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 DCHS2 MDN1 SASS6 TDP1

5.64e-05154118516fdafb5c64d2db321554f87129a962d113f1668
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA7 NFIL3 MYO1F UNG PADI2

6.00e-0515611855b56217336771baf57d791efcb4e206c6aea83b1
ToppCellfacs-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 MYO1F ZFHX3 NCR1 PADI2

6.18e-051571185a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL20A1 OSBP ZBED6 GJA10 DMBT1

6.37e-05158118512661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL20A1 OSBP ZBED6 GJA10 DMBT1

6.37e-051581185e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL20A1 OSBP ZBED6 GJA10 DMBT1

6.37e-0515811850792c39e6fc0745095af7812de2d50949540d60f
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tregs|GI_large-bowel / Manually curated celltypes from each tissue

THADA KL PTPN13 TIAM1 PKHD1

7.17e-0516211859a5e65c45f73a6a685b8362aa2e6aea77181caa3
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOGARAM1 UNG WDR90 NCR1 PADI2

7.38e-0516311859c91415a56b12b3b2d15d253bb59db8bedf49ea2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MFGE8 PTPN13 PIK3C2G PIK3R1 TNFAIP3

7.60e-0516411858f3255d7f67890389a768453492243ea982eb38a
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DCHS2 ISLR IRF9 TENM4 FCER2

8.05e-05166118565dafed953b01a9830b54309af75c7a561e88336
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3R1 MYO1F TNFAIP3 NCR1 PADI2

8.28e-051671185aef22535a76e93472bcedacbb2c6991f3c9c8cd5
ToppCellfacs-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3R1 MYO1F LTA4H NCR1 PADI2

8.51e-05168118574dc46738f1d0a448df6c9b8288b515d92697792
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEP192 THADA TENM4 FAM180A WDR90

9.00e-051701185ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHMT1 NUP133 SASS6 UNG LTA4H

9.77e-0517311856c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUPT20H B3GNT5 DTX1 TENM4 SESN2

1.00e-04174118528ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SNX29P2 DTX1 SPTBN1 FCER2 DTX4

1.06e-041761185ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR TENM4 TIAM1 NRXN2

1.06e-041761185fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-B_cell-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GNT5 DTX1 CAPG FCER2 NOTCH2

1.06e-04176118527c132e9852717cbc345af7a1fc390e9ea589416
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR TENM4 TIAM1 NRXN2

1.06e-041761185f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellASK452-Endothelial-Lymphatic|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

DPYSL3 RELN ZNF595 KL STARD9

1.06e-041761185b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GNT5 DTX1 CAPG FCER2 NOTCH2

1.06e-041761185259d1864fb0a6d2feddc90bc715e2bccbb373792
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 ARHGEF28 ABCC9 ISLR NELL1

1.09e-041771185921783ed0fe20294d2f384d9136924b679df01bb
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR TENM4 PIK3R1 PYGM NOTCH2

1.09e-0417711857af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KL PIK3C2G PKHD1 ADGRL2 KNG1

1.09e-041771185c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 TENM4 SORCS2 PADI2 KNG1

1.12e-041781185dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 TENM4 PADI2 KNG1

1.12e-0417811854df6218b20c2f076c22346d23260964cc0d73e65
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 TRIM24 PTPN13 TENM4 LTA4H

1.15e-041791185fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 TENM4 SORCS2 PADI2 KNG1

1.15e-041791185d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 ARHGEF28 ABCC9 ISLR NELL1

1.15e-041791185445eeb0356d9fd894aa33dd9f45d893b21424149
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 KL PIK3C2G ADGRL2 KNG1

1.15e-041791185666072c0e8448dbaec1683d18368ec2502453f90
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 TENM4 SORCS2 PADI2 KNG1

1.15e-0417911852e49b215b71438400aebb483f2c2c08d5e956961
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 SORCS2 PADI2 KNG1

1.18e-0418011859e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 SORCS2 PADI2 KNG1

1.18e-041801185eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 SORCS2 PADI2 KNG1

1.18e-041801185a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD14A ZNF567 SHMT1 SESN2 WDR90

1.21e-041811185c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCellfacs-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPG MFGE8 PKHD1 DMBT1 NOTCH2

1.24e-04182118545faefd7cbeac84d2c58650530b902af6ce921f8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 KL PIK3C2G ADGRL2 KNG1

1.27e-0418311852e831a4d99c6f983793df71c0994124c943c6da9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN APOB TENM4 PIK3C2G PKHD1

1.30e-0418411852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN APOB TENM4 PIK3C2G PKHD1

1.30e-041841185ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN APOB TENM4 PIK3C2G PKHD1

1.30e-0418411852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 TENM4 SORCS2 PADI2

1.34e-04185118503f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

B3GNT5 CAPG PIK3R1 ZFHX3 TNFAIP3

1.34e-0418511854a5e70ac41e5f3b25a773304ffef3c2a3dd5549d
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 PTPN13 PTPRF DOK4 LTA4H

1.37e-041861185e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

DPYSL3 ABCC9 CEP192 NRXN2 SORCS2

1.37e-0418611851bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DCDC1 CFAP43 PKHD1 IGSF9

1.37e-0418611855c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 ARHGEF28 COL20A1 APC2 CAMKV

1.37e-0418611852fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

DPYSL3 ABCC9 CEP192 NRXN2 SORCS2

1.37e-04186118559db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 TRIM24 PTPN13 TENM4 LTA4H

1.37e-041861185e83718fabb057100835d3357df407f283d23fe16
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPYSL3 TRIM24 KIDINS220 THRB ADGRL2

1.41e-041871185ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 SORCS2 PADI2 KNG1

1.41e-04187118585e58a312fc325e4063a2d250666b99b8f99beb6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 SORCS2 PADI2 KNG1

1.41e-04187118552b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 PTPN13 PTPRF DOK4 LTA4H

1.41e-041871185201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DCDC1 CFAP43 MAPK8IP3 PKHD1

1.41e-041871185c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 PTPN13 PTPRF SORCS2 PKHD1

1.41e-04187118558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 PTPN13 PTPRF DOK4 LTA4H

1.44e-04188118543a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

PRUNE2 SHMT1 ANGPTL8 TENM4 PTPRF

1.44e-0418811854dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCHS2 DPYSL3 ABCC9 ISLR NRXN2

1.48e-041891185f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellHealthy_donor-NK_CD56bright|Healthy_donor / disease group, cell group and cell class (v2)

MFGE8 STARD9 PIK3R1 TNFAIP3 NCR1

1.48e-0418911859eac380a3bb4b685effb52d816e1960972660646
ToppCell10x_3'_v3-spleen_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DTX1 CHD1 NFIL3 MYO1F TNFAIP3

1.48e-0418911850fe8901e10c619c93b7788792da1706a32102c6e
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 PTPN13 THRB SORCS2 PKHD1

1.48e-041891185830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 PIK3C2G PKHD1 ADGRL2 KNG1

1.48e-041891185e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PTPN13 PTPRF DOK4 SORCS2 DMBT1

1.48e-0418911852d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 ABCC9 FAM180A SORCS2 MYBPC3

1.48e-0418911854dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 ABCC9 FAM180A SORCS2 MYBPC3

1.48e-0418911850d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 PPFIBP2 NELL1 TENM4 NOTCH2

1.48e-04189118545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DTX1 NELL1 TENM4 PADI2 KNG1

1.52e-0419011853dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTBN1 STARD9 PIK3R1 TNFAIP3 NCR1

1.55e-041911185f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTBN1 STARD9 PIK3R1 TNFAIP3 NCR1

1.55e-0419111851161e465c50c2071764279e01cf08b1048cce0e3
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 RELN NELL1 PTPRF FCER2

1.55e-0419111853387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPTBN1 STARD9 PIK3R1 TNFAIP3 NCR1

1.55e-0419111857a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGEF28 NELL1 TENM4 PKHD1 KNG1

1.55e-041911185fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellControl-Lymphoid_T/NK-NK_CD56bright|Control / Disease group, lineage and cell class

SPTBN1 STARD9 PIK3R1 TNFAIP3 NCR1

1.55e-041911185e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYSL3 COL20A1 APC2 KIDINS220 CAMKV

1.55e-041911185c7b95a5f9185d533c08754ce2e4ce91533eb612e
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPTBN1 STARD9 PIK3R1 TNFAIP3 NCR1

1.55e-041911185c023ca893ceae19b54967096f6e2588dc39fa268
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGEF28 NELL1 TENM4 PKHD1 KNG1

1.55e-0419111850965f621ebcd92ccdeb21cc27022180ce3cfe910
DiseaseColorectal Carcinoma

APC2 EML2 CHD1 APOB ISLR NELL1 OSBP KL TIAM1 PKHD1 UNG SESN2 NCR1 PZP

5.72e-0770211414C0009402
DiseaseAbnormality of nervous system morphology

APC2 MAPK8IP3 GOT2

6.61e-06101143C4022810
Diseasekiller cell immunoglobulin-like receptor 2DL5A measurement

FCAR NCR1

4.43e-0531142EFO_0801745
Diseaseinsulin-like growth factor-binding protein 3 measurement

MAPK8IP3 SORCS2

1.47e-0451142EFO_0801703
Diseaseintraocular pressure measurement

RELN SPTBN1 ERVK13-1 DRAM2 MAPK8IP3 THADA PKHD1 ZFHX3 MYBPC3

1.65e-045091149EFO_0004695
Diseaseurate measurement

DNAJC13 DCDC1 ISLR PTPRF NRXN2 PIK3R1 PKHD1 PYGM SESN2 GJA10 ADGRL2 NOTCH2

1.83e-0489511412EFO_0004531
Diseasecortical surface area measurement

DCHS2 DPYSL3 RELN DNAJC13 DCDC1 SPTBN1 EML2 NELL1 THADA PTPRF PIK3R1 PKHD1 IGSF9 ZFHX3 ADGRL2

2.12e-04134511415EFO_0010736
Diseasecortical thickness

RELN DCDC1 SPTBN1 EML2 ABCC9 MAPK8IP3 NELL1 THADA PTPRF PIK3R1 PI4KA PKHD1 IGSF9

3.73e-04111311413EFO_0004840
Diseasekiller cell immunoglobulin-like receptor 2DL4 measurement

FCAR NCR1

9.52e-04121142EFO_0008197
Diseaseresponse to tenofovir

RELN KIDINS220 ADGRL2

1.02e-03511143EFO_0009279
Diseasecreatinine measurement, glomerular filtration rate

DCDC1 THADA PIK3R1 ADGRL2

1.12e-031171144EFO_0004518, EFO_0005208
Diseasebrain measurement, neuroimaging measurement

DCHS2 DPYSL3 DCDC1 SPTBN1 NELL1 THADA IGSF9 ZFHX3

1.36e-035501148EFO_0004346, EFO_0004464
Diseasediffuse idiopathic skeletal hyperostosis

PIK3R1 NFIL3

1.50e-03151142EFO_0007236
Diseasebilirubin measurement

DCHS2 ABCC9 APOB SLC22A16 NFIL3 DMBT1 ADGRL2

1.68e-034421147EFO_0004570
Diseasesphingomyelin 14:0 measurement

THADA ZFHX3

1.94e-03171142EFO_0010390
DiseaseAnimal Mammary Neoplasms

RASA1 STAT5A PIK3R1 KNG1

2.28e-031421144C0024667
DiseaseMammary Carcinoma, Animal

RASA1 STAT5A PIK3R1 KNG1

2.28e-031421144C1257925
DiseaseC-reactive protein measurement

DCHS2 ARHGEF28 EML2 APOB CEP192 ZNF112 SERPINA2 MAPK8IP3 THRB PTPRF CAMKV MYBPC3

2.46e-03120611412EFO_0004458
Diseaseeosinophil percentage of leukocytes

CCDC18 CHD1 ABCA7 THADA PELP1 NFIL3 SESN2 TNFAIP3 NOTCH2

2.47e-037461149EFO_0007991
Diseasediet measurement

APOB NELL1 THADA TENM4 PTPRF FARS2 PIK3R1 PKHD1 ZFHX3 ADGRL2 PADI2

2.50e-03104911411EFO_0008111
DiseaseManic Disorder

RELN TENM4 STARD9

2.65e-03711143C0024713
Diseaseneuroimaging measurement

DCHS2 DPYSL3 RELN DCDC1 SPTBN1 EML2 MAPK8IP3 NELL1 THADA PKHD1 IGSF9

2.89e-03106911411EFO_0004346
DiseaseDrugs used in diabetes use measurement

PTGFRN THADA KL ZFHX3 NOTCH2

3.17e-032551145EFO_0009924
DiseaseHodgkin Disease

RELN TNFAIP3

3.25e-03221142C0019829
DiseaseManic

RELN TENM4 STARD9

3.46e-03781143C0338831
Diseaseinterleukin 10 measurement

SUPT20H SORCS2 ADGRL2

3.46e-03781143EFO_0004750
DiseaseOvarian Serous Adenocarcinoma

TRIM24 CAMKV

3.55e-03231142C1335177
Diseasehippocampal sclerosis of aging

ABCC9 SORCS2

3.55e-03231142EFO_0005678
DiseaseDepression, Bipolar

RELN TENM4 STARD9

3.59e-03791143C0005587
Diseaselow density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram

RELN ZFHX3

3.86e-03241142EFO_0004611, EFO_0006329, EFO_0007871
DiseaseCarcinoma, Pancreatic Ductal

DTX1 DTX4

3.86e-03241142C0887833

Protein segments in the cluster

PeptideGeneStartEntry
HQANSHKERGWEQFT

UNG

221

P13051
KLDHSVSSTNGHRWQ

COP1

206

Q8NHY2
NHEKEHWLLIQDAST

CFAP43

1101

Q8NDM7
QDQHSWENVSRHLKA

ERVK13-1

391

Q9NX77
TWSLFANTVAHELGH

ADAM21

331

Q9UKJ8
QQATESHHRKEAWQS

AFTPH

591

Q6ULP2
DWSEKDQHSGQLHVH

GJA10

321

Q969M2
ALHVDITHWNDSVKQ

DPYSL3

136

Q14195
EQHNKSVHVAGLSWV

AKTIP

261

Q9H8T0
ALESWKHMNSSEQAH

ADGRL2

621

O95490
FIGWGSQSSKVQIHH

ABCC9

46

O60706
ADKQSHILWALTGHV

ANGPTL8

156

Q6UXH0
VIWNEVHHKTEFGSN

DTX4

571

Q9Y2E6
SHIHNTWETEETLKQ

CHD1

326

O14646
EKLLEATHNNAVWNH

FAM200A

226

Q8TCP9
KNLTAWAHSLDAQDS

ABCA7

1456

Q8IZY2
WSGDLSHHQSEVQVS

NBPF4

486

Q96M43
SAWNVAKEGTHGSHV

PZP

1136

P20742
QKGHATDEWFLLSSH

RASA1

681

P20936
WDSTGHSLNEAHQIS

PIK3C2G

71

O75747
SNVIAHEISHSWTGN

LTA4H

291

P09960
HEISHSWTGNLVTNK

LTA4H

296

P09960
EVVLLHGKAFNSHTW

ABHD14A

96

Q9BUJ0
HGKAFNSHTWEQLGT

ABHD14A

101

Q9BUJ0
NVSHKLWTAAGSGHQ

ARHGEF28

1621

Q8N1W1
SWLHEINSQELEKAH

NUP133

936

Q8WUM0
NAVDDHGKSALHWAA

NOTCH2

1971

Q04721
HGKSALHWAAAVNNV

NOTCH2

1976

Q04721
EKKSDGSHQRWIHQE

DCDC1

1201

M0R2J8
NWTALISASKEGHVH

KIDINS220

71

Q9ULH0
QSLLKEEASWQQSHH

MDN1

3366

Q9NU22
DHWHLSDLGQLQSSS

MAPK8IP3

231

Q9UPT6
GLQKDHALWDHTAQN

NCR1

241

O76036
GNWDNHSHKKNLFET

MFGE8

346

Q08431
AFNWVKASQTELHVH

ITGB1BP2

241

Q9UKP3
WKLHQGKANEHTSEN

LRRC53

316

A6NM62
SHNLISDFAWSDLHN

ISLR

106

O14498
VENWHSHTALNKEAS

FCAR

246

P24071
TNNWEDHLAVKHFSV

HSP90AA5P

141

Q58FG0
EHWHQKELSGKTQNS

NFIL3

396

Q16649
HSGNFGTDLEQKLHW

DRAM2

181

Q6UX65
EQDFLTKHASHTGSW

FCER2

206

P06734
TLFAGHKLNDNEWHT

NRXN2

811

Q9P2S2
KHQNWVSGLSQHTGL

PI4KA

1086

P42356
WSESQEHIHGLDKLQ

GABRD

196

O14764
GAQTFSLKHSEHVWV

PADI2

36

Q9Y2J8
LPHHDEKTWNVGSSN

PIK3R1

616

P27986
SQGLKHTESWEQELH

PELP1

251

Q8IZL8
AAAHHAESKNGWTLR

OSBP

526

P22059
VWNEIHHKTEFGSNL

DTX1

576

Q86Y01
DGQWHKVALSVSASH

NELL1

146

Q92832
KEWFEESLSQVNHHS

PPFIBP2

86

Q8ND30
ALHWLVLGTHTSDEQ

RBBP7

61

Q16576
QHGKHSAQWALDDVL

RELN

1581

P78509
QTTSDHDGKDNYHWN

DCHS2

3221

Q6V1P9
DSSCWDSLLHHKQDG

PANX3

81

Q96QZ0
LHSAHTKLQTWGQIF

KICS2

216

Q96MD2
VTSKHNNDTQHIWES

HSP90B1

211

P14625
TSHGHLEDLQDLWKN

B3GNT5

321

Q9BYG0
AAQKTDTSHHDQGDW

SERPINA2

31

P20848
SLWEHSTKNHLQLEG

APOB

3561

P04114
ALWNLSAHSTENKAA

APC2

556

O95996
ISHEWISGNAASDKN

CAMKV

281

Q8NCB2
HQENHAKWKISADSQ

CCDC18

1231

Q5T9S5
GSWSIGHSHFQQVKD

COL20A1

186

Q9P218
DSVHNVWHQEAGKTI

FAM172A

321

Q8WUF8
LGSANVISWNHHEFE

DNAJC13

801

O75165
QDEHFLGIESLWNHK

DRC7

331

Q8IY82
LENHGTTDVKWHLSS

CEP192

2296

Q8TEP8
QVTLNFWEESHGSSH

IRF9

346

Q00978
HGHQKDIWAQSLVSL

FAM180A

141

Q6UWF9
NAIVKSKQHSWHESD

GPATCH2L

101

Q9NWQ4
SKQHSWHESDSFTEN

GPATCH2L

106

Q9NWQ4
QQHGKGASIWDTFTH

KL

81

Q9UEF7
HNGWKTEHLASSSED

KNG1

516

P01042
EEVSHLHLWIGQQSS

CAPG

56

P40121
GQDKLVHLWSSDSHQ

EML2

396

O95834
WLSHNCQHSEDAGVI

DMBT1

946

Q9UGM3
RNEWASHTAALTNKH

SASS6

196

Q6UVJ0
WHHITGSQNIAEASS

DOK4

271

Q8TEW6
ASHLGDQTWQESQHG

PTPN13

1266

Q12923
AWHKHNTDAGLLTTV

PTPRF

461

P10586
NGAHKDADLWSSHDK

SHMT1

6

P34896
GHNRSWHKVAEAVSS

PTGFRN

381

Q9P2B2
HSVTQAGVQWHDLSS

SNX29P2

226

Q8IUI4
EHIQALLKTGEHTWS

SESN2

176

P58004
AHGHLQSATDTWENL

THADA

606

Q6YHU6
QGTNHLIEDFASLWH

PRUNE2

756

Q8WUY3
VVFHNHSNWSLEDTG

SLC22A16

61

Q86VW1
LKGDATHNQAMVHWT

SORCS2

141

Q96PQ0
HLTWSHTLKEQTNSG

SHLD3

101

Q6ZNX1
FTENWVAGEHHILKA

PKHD1

2116

P08F94
HSNVTTATKADHWSQ

STARD9

1656

Q9P2P6
EAHNKKASSRSWHNV

SPTBN1

2211

Q01082
HGSQDHNATATVLWD

STAT5A

471

P42229
NLKKEGSTHNWQHIT

GOT2

361

P00505
FHQGQHWDQKSSRSL

TNRC18

2871

O15417
TQEEWQHLDHAQKTL

ZNF567

16

Q8N184
TSNLIHADWHQKTQG

TDP1

281

Q9NUW8
GLHQDNSSNGKSEWL

TRIM24

791

O15164
SKSILNRHQWTHSEE

ZNF343

336

Q6P1L6
WSASLNEHKNIHTGE

ZNF595

491

Q8IYB9
QQHWSGHSAEISTLA

WDR90

1151

Q96KV7
DHNSIPKHAVWVENS

TIAM1

486

Q13009
GWDHGTTHLINAAKL

TNFAIP3

316

P21580
HVEHTSQGAKWVDTQ

PYGM

206

P11217
DVHSITSDNHKWTQE

SUPT20H

176

Q8NEM7
TEAHVATNAQGSHWK

THRB

226

P10828
WSLDKHHALNIQSGI

TENM4

1171

Q6N022
SMEASGHLSTNLWHA

TECPR2

686

O15040
GHLSTNLWHAVTDDD

TECPR2

691

O15040
LTKEAHGHWECSASN

IGSF9

476

Q9P2J2
EHGNGFNWSSKLKDH

ZNF112

501

Q9UJU3
QATHPIHWAVANKDS

ZBED6

311

P86452
QSQKIHLTVDIWTHD

ZBED6

476

P86452
WSHLAQHQLLHTGEK

ZNF689

441

Q96CS4
ENGCKDWQHLSHILS

ZMYM5

606

Q9UJ78
SEVGHWRHIAQTSKA

TRIP11

186

Q15643
LQEAEHWSKQHTELS

SPZ1

251

Q9BXG8
DSHWKLAEAHVNLAQ

TTC23

81

Q5W5X9
SNHLAHGADTDWLLA

TOGARAM1

601

Q9Y4F4
TSAHQWDLLHAGLDA

FARS2

156

O95363
HQQWTELNSTHLPDK

ZFHX3

21

Q15911
RFHWQSHNVKQSGVD

MYO1F

6

O00160
WVDLSSKVGQHLQLH

MYBPC3

196

Q14896