Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of mitotic cell cycle phase transition

APEX1 TTK

5.40e-0340262GO:1901990
DomainKinase-like_dom

RAPH1 TTK

1.17e-0254262IPR011009
Pubmed

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.

RAPH1 TTK RNF19A

1.60e-053266317015433
InteractionUNG interactions

APEX1 CAPN11

6.63e-054362int:UNG
InteractionRAPH1 interactions

RAPH1 APEX1

1.48e-046462int:RAPH1
InteractionVPS8 interactions

APEX1 TTK

1.52e-046562int:VPS8
InteractionNPY2R interactions

APEX1 TTK

1.57e-046662int:NPY2R
InteractionFGFR1 interactions

RAPH1 APEX1 TTK

5.72e-0463263int:FGFR1
InteractionCDCA8 interactions

APEX1 TTK

6.37e-0413362int:CDCA8
InteractionCNTROB interactions

APEX1 TTK

9.90e-0416662int:CNTROB
InteractionCEP162 interactions

APEX1 TTK

1.01e-0316862int:CEP162
InteractionTTK interactions

APEX1 TTK

1.07e-0317362int:TTK
CoexpressionGSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_DN

ACBD7 APEX1 CAPN11

8.48e-0619963M8094
CoexpressionGSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP

RAPH1 RNF19A

5.60e-0416262M8243
CoexpressionGSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

RAPH1 TTK

6.61e-0417662M9137
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP

RAPH1 TTK

7.06e-0418262M8126
CoexpressionDARWICHE_PAPILLOMA_RISK_LOW_DN

RAPH1 RNF19A

7.37e-0418662MM498
CoexpressionLEE_BMP2_TARGETS_DN

RAPH1 APEX1 TTK

7.56e-0490463M2325
CoexpressionFLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN

ACBD7 TTK

7.69e-0419062M761
CoexpressionPRC2_EZH2_UP.V1_DN

TTK RNF19A

7.85e-0419262M2737
CoexpressionWIERENGA_STAT5A_TARGETS_DN

TTK CAPN11

7.93e-0419362M2213
CoexpressionLEE_BMP2_TARGETS_DN

RAPH1 APEX1 TTK

8.01e-0492263MM1068
CoexpressionGSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_UP

APEX1 RNF19A

8.26e-0419762M9725
CoexpressionGSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN

APEX1 CAPN11

8.35e-0419862M8874
CoexpressionGSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_DN

RAPH1 RNF19A

8.35e-0419862M6578
CoexpressionGSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_DN

RAPH1 TTK

8.43e-0419962M8587
CoexpressionGSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN

APEX1 RNF19A

8.52e-0420062M9049
CoexpressionGSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP

RAPH1 RNF19A

8.52e-0420062M6668
CoexpressionGSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_UP

TTK RNF19A

8.52e-0420062M6429
CoexpressionGSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN

RAPH1 RNF19A

8.52e-0420062M4889
CoexpressionGSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN

APEX1 RNF19A

8.52e-0420062M6240
CoexpressionGSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_DN

APEX1 TTK

8.52e-0420062M8204
CoexpressionGOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP

APEX1 RNF19A

8.52e-0420062M3038
CoexpressionGSE5960_TH1_VS_ANERGIC_TH1_DN

APEX1 RNF19A

8.52e-0420062M5638
CoexpressionDARWICHE_PAPILLOMA_RISK_HIGH_DN

RAPH1 RNF19A

8.60e-0420162MM500
CoexpressionPAL_PRMT5_TARGETS_UP

APEX1 TTK

8.86e-0420462M10688
CoexpressionPAL_PRMT5_TARGETS_UP

APEX1 TTK

9.38e-0421062MM1172
CoexpressionHE_LIM_SUN_FETAL_LUNG_C6_DEUTEROSOMAL_CELL

ACBD7 TTK

1.04e-0322162M45789
CoexpressionDARWICHE_SKIN_TUMOR_PROMOTER_DN

RAPH1 RNF19A

1.08e-0322562MM496
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ACBD7 CAPN11

6.44e-059462c73e99890431750b74f984de5c82e33533ab708b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ACBD7 CAPN11

6.44e-0594629664f74bc0168c92fb8a68cad628323c476f6103
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ACBD7 CAPN11

6.44e-0594621bda61101f45f5c4a68453087b880fdc6d9acfca
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACBD7 TTK

8.83e-05110623639fb5fc02eca509cb220295bc3e6064c23baab
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACBD7 TTK

8.83e-0511062ff196c71aa2a21cdd812958bd163fa6b91bd2352
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACBD7 TTK

8.83e-051106246635a130453c2fa304f0e09561b2a267c9ceb31
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACBD7 TTK

8.83e-0511062438bf761ab0a25e3dc9244c23ae2c2d68a169c7f
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ACBD7 TTK

1.12e-04124621483be8700eca7e2c288784a290d945d4022b17f
ToppCellNS-moderate-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ACBD7 RNF19A

1.23e-04130621491e8975520e99c527a5b5bee64875d124f7bf4
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

APEX1 TTK

1.62e-0414962e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

APEX1 CAPN11

1.66e-04151628ffd71d847fe1aeebe7f43c4b6ca73efb19d6041
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACBD7 TTK

1.89e-04161622165897924c790fec43502283f1df221c56c1e9f
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

APEX1 CAPN11

1.99e-0416562dc70e050465d1f05bb4115356dc978aa581149b5
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

APEX1 TTK

2.01e-0416662c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

RAPH1 TTK

2.01e-0416662ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

RAPH1 TTK

2.01e-0416662a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACBD7 TTK

2.11e-041706221bfe070e63722672176052b386167ea4c3dc4e5
ToppCell10x5'-Lung-Lymphocytic_NK-Cycling_NK|Lung / Manually curated celltypes from each tissue

ACBD7 TTK

2.18e-0417362d815832f89f70662706620e3b03ebb1dabec0034
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPH1 TTK

2.21e-04174629d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPH1 TTK

2.21e-041746253cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

APEX1 CAPN11

2.23e-0417562df369b96a780272ed52e23c8627fc63c22efa445
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACBD7 TTK

2.26e-04176623e7647364c13beade9ca278c7ce8e89546e0b060
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACBD7 TTK

2.26e-0417662a55572470de6af6cbf29ed4f785fdca62d24cd23
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RAPH1 RNF19A

2.42e-04182627b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACBD7 TTK

2.44e-041836229b62dd542bc3f8df843998f577724f3818d4271
ToppCellIIF-Lymphocyte-T_NK-T_NK_proliferative|IIF / Disease, Lineage and Cell Type

ACBD7 TTK

2.47e-0418462ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ACBD7 TTK

2.50e-04185626aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c5-WDR74|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAPH1 CAPN11

2.50e-041856268edb1bb03ed221d49e583123ca4de14252d7bc5
ToppCellmegakaryocytic-Megakaryocyte|World / Lineage and Cell class

TTK CAPN11

2.52e-0418662acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-CMP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

APEX1 CAPN11

2.55e-0418762624e663d5ddc6b8fefbd0e3207bf1928c2478b7b
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RAPH1 TTK

2.63e-04190627be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellCV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

APEX1 TTK

2.69e-0419262a249787f7e2f50af49bd7d4752c411a067a5e3d3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACBD7 TTK

2.77e-04195625556f280a5b42bda6e47b9d308946b7d5f4fa656
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TTK CAPN11

2.77e-0419562c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

APEX1 TTK

2.80e-0419662b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCelldistal-Hematologic-Proliferating_NK/T-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACBD7 TTK

2.83e-041976204b10879e48c101d1de449db0bc6b6484090b965
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACBD7 TTK

2.86e-0419862c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCellSepsis-Leuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, condition lineage and cell class

APEX1 TTK

2.89e-0419962a2f154b15087803958a656d2a41b6d83fd37b32f
Drugneocuproine

APEX1 TTK

3.84e-053762CID000065237
DrugD90A

APEX1 RNF19A

2.05e-048562CID000023715
DrugN-methyl-1(R)-aminoindan

APEX1 TTK

4.93e-0413262CID005494442
Drugparaquat

APEX1 RNF19A

1.11e-0319962CID000015938
Drughydroxylamine

APEX1 RNF19A

1.67e-0324462CID000000787
DiseaseLiver carcinoma

APEX1 TTK

4.22e-0350762C2239176
Diseaselymphocyte count

RAPH1 RNF19A

3.23e-02146462EFO_0004587

Protein segments in the cluster

PeptideGeneStartEntry
GLRAWIKKKGLDWVK

APEX1

71

P27695
GLLEFKILWKKLKKW

CAPN11

631

Q9UMQ6
KILWKKLKKWMDIFR

CAPN11

636

Q9UMQ6
GVLWLKDDGKKSWKK

RAPH1

401

Q70E73
LKGKAKWEAWNLKKG

ACBD7

51

Q8N6N7
GKKPWSRKKKILWQL

RNF19A

351

Q9NV58
SWLKKKKSIDPWERK

TTK

611

P33981