Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

GPM6A KCNH8 SLC27A6 APOA5 SLC38A9 OTOP2 SLC44A2 MFSD9 GRIK4 GRIN2C GRIN2D APOE TMEM87A SLC4A1 GJD4 SLC5A4 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13 TAP1

4.32e-11128911029GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

GPM6A KCNH8 SLC27A6 SLC38A9 OTOP2 SLC44A2 MFSD9 GRIK4 GRIN2C GRIN2D TMEM87A SLC4A1 GJD4 SLC5A4 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13 TAP1

1.63e-10118011027GO:0022857
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A SLC4A1 SLC5A4 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

8.68e-1075811021GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A SLC4A1 SLC5A4 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

1.94e-0979311021GO:0015075
GeneOntologyMolecularFunctionchannel activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A GJD4 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SCN7A OTOP1 TRPV3

2.97e-0852511016GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A GJD4 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SCN7A OTOP1 TRPV3

3.05e-0852611016GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A CLCN1 CLCN2 CLCNKA CLCNKB SCN7A OTOP1 TRPV3

2.32e-0745911014GO:0005216
GeneOntologyMolecularFunctionvoltage-gated chloride channel activity

CLCN1 CLCN2 CLCNKA CLCNKB

2.79e-07111104GO:0005247
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A SLC5A4 SLC6A1 SLC12A2 SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

3.34e-0762711016GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A SLC5A4 SLC6A1 SLC12A2 SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

7.14e-0766411016GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

GPM6A KCNH8 GRIK4 GRIN2C GRIN2D TMEM87A SLC5A4 SLC6A1 SLC12A2 SCN7A SLC13A5 TRPV3 ZDHHC13

1.71e-0646511013GO:0046873
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

CLCN1 CLCN2 CLCNKA CLCNKB

1.96e-06171104GO:0008308
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

5.94e-061251107GO:0015108
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

VLDLR DRD5 P2RY12 OR13C8 ADGRB2 ADGRB3 GRIK4 GRIN2C GRIN2D PTAFR NPFFR1 LHCGR TAS2R3 ADRB1 GPR153 APLNR SCN7A GPR156 OR10A6 IL1RL1 OR56B4

1.35e-05135311021GO:0004888
GeneOntologyMolecularFunctiongated channel activity

KCNH8 GRIK4 GRIN2C GRIN2D TMEM87A CLCN1 CLCN2 CLCNKA CLCNKB SCN7A

1.60e-0533411010GO:0022836
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC27A6 SLC38A9 GRIK4 GRIN2C GRIN2D SLC6A1 SLC13A5 SLC47A1

1.93e-052071108GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC27A6 SLC38A9 GRIK4 GRIN2C GRIN2D SLC6A1 SLC13A5 SLC47A1

2.00e-052081108GO:0005342
GeneOntologyMolecularFunctionmonoatomic cation channel activity

GPM6A KCNH8 OTOP2 GRIK4 GRIN2C GRIN2D TMEM87A SCN7A OTOP1 TRPV3

2.01e-0534311010GO:0005261
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

2.04e-051511107GO:0008509
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC38A9 GRIK4 GRIN2C GRIN2D SLC6A1 SLC47A1

2.52e-051051106GO:0015171
GeneOntologyMolecularFunctionvaline-tRNA ligase activity

VARS2 VARS1

3.01e-0521102GO:0004832
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC27A6 SLC38A9 GRIK4 GRIN2C GRIN2D SLC4A1 SLC6A1 SLC13A5 SLC47A1

3.55e-052931109GO:0008514
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

4.53e-051711107GO:0015103
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

DRD5 GRIK4 GRIN2C GRIN2D ADRB1

5.88e-05751105GO:0098960
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNH8 GRIN2C GRIN2D CLCN1 CLCN2 CLCNKA CLCNKB

6.72e-051821107GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNH8 GRIN2C GRIN2D CLCN1 CLCN2 CLCNKA CLCNKB

7.20e-051841107GO:0022832
GeneOntologyMolecularFunctionG protein-coupled receptor activity

DRD5 P2RY12 OR13C8 ADGRB2 ADGRB3 PTAFR NPFFR1 LHCGR TAS2R3 ADRB1 GPR153 APLNR GPR156 OR10A6 OR56B4

1.01e-0488411015GO:0004930
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK4 GRIN2C GRIN2D

1.05e-04171103GO:0004970
GeneOntologyMolecularFunctionneurotransmitter receptor activity

DRD5 GRIK4 GRIN2C GRIN2D ADRB1

2.30e-041001105GO:0030594
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIK4 GRIN2C GRIN2D ADRB1

3.35e-04601104GO:0099529
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

GRIK4 SLC5A4 SLC6A1 SLC12A2 SCN7A SLC13A5

3.71e-041711106GO:0015081
GeneOntologyMolecularFunctionglutamate receptor activity

GRIK4 GRIN2C GRIN2D

4.32e-04271103GO:0008066
GeneOntologyMolecularFunctionphosphatidylcholine-sterol O-acyltransferase activator activity

APOA5 APOE

4.45e-0461102GO:0060228
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2C GRIN2D

8.24e-0481102GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2C GRIN2D

8.24e-0481102GO:0004972
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

APOA5 APOE CLU

8.60e-04341103GO:0050750
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A4 SLC6A1 SLC12A2 SLC13A5

1.05e-03811104GO:0015370
GeneOntologyMolecularFunction2-acylglycerol-3-phosphate O-acyltransferase activity

LPCAT1 LPGAT1

1.06e-0391102GO:0047144
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC44A2 SLC4A1 SLC5A4 SLC6A1 SLC12A2 SLC13A5 SLC47A1

1.27e-032961107GO:0015291
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

APOA5 APOE CLU

1.29e-03391103GO:0070325
GeneOntologyMolecularFunctionchloride channel activity

CLCN1 CLCN2 CLCNKA CLCNKB

1.31e-03861104GO:0005254
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC38A9 SLC47A1

2.25e-03131102GO:0061459
GeneOntologyMolecularFunctionG protein-coupled purinergic nucleotide receptor activity

P2RY12 PTAFR

2.25e-03131102GO:0045028
GeneOntologyMolecularFunctionmonoatomic anion channel activity

CLCN1 CLCN2 CLCNKA CLCNKB

2.54e-031031104GO:0005253
GeneOntologyMolecularFunctionaminoacyl-tRNA editing activity

VARS2 VARS1

2.62e-03141102GO:0002161
GeneOntologyMolecularFunctionintegrin binding

COL3A1 ACTN4 ACTN1 ACTN3 DMP1

2.85e-031751105GO:0005178
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIK4 GRIN2C GRIN2D

3.83e-03571103GO:1904315
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A1 SLC12A2

3.87e-03171102GO:0015378
GeneOntologyMolecularFunctionO-acyltransferase activity

LPCAT1 HHAT LPGAT1

4.23e-03591103GO:0008374
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A4 SLC6A1 SLC12A2 SLC13A5

4.26e-031191104GO:0015294
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A1 SLC12A2

4.84e-03191102GO:0015373
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC44A2 SLC4A1 SLC5A4 SLC6A1 SLC12A2 SLC13A5 SLC47A1 TAP1

4.90e-034771108GO:0022804
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC38A9 SLC47A1

5.36e-03201102GO:0015174
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIK4 GRIN2C GRIN2D

5.55e-03651103GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIK4 GRIN2C GRIN2D

5.55e-03651103GO:0022824
GeneOntologyMolecularFunctioncalcium channel activity

GPM6A GRIN2C GRIN2D TRPV3

5.66e-031291104GO:0005262
GeneOntologyMolecularFunction1-acylglycerol-3-phosphate O-acyltransferase activity

LPCAT1 LPGAT1

5.90e-03211102GO:0003841
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC4A1 SLC5A4 SLC6A1 SLC12A2 SLC13A5 SLC47A1

6.46e-033011106GO:0022853
GeneOntologyMolecularFunctionprotein-hormone receptor activity

LHCGR ADIPOR2

6.46e-03221102GO:0016500
GeneOntologyMolecularFunctionnucleotide receptor activity

P2RY12 PTAFR

6.46e-03221102GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

P2RY12 PTAFR

6.46e-03221102GO:0001614
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A1 SLC12A2

7.05e-03231102GO:0015377
GeneOntologyMolecularFunctioncholesterol transfer activity

APOA5 APOE

7.67e-03241102GO:0120020
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIK4 GRIN2D

7.67e-03241102GO:0099507
GeneOntologyMolecularFunctionlysophosphatidic acid acyltransferase activity

LPCAT1 LPGAT1

7.67e-03241102GO:0042171
GeneOntologyMolecularFunctionlysophospholipid acyltransferase activity

LPCAT1 LPGAT1

7.67e-03241102GO:0071617
GeneOntologyMolecularFunctionsterol transfer activity

APOA5 APOE

8.31e-03251102GO:0120015
GeneOntologyMolecularFunctionsialic acid binding

MAG ST8SIA2

8.31e-03251102GO:0033691
GeneOntologyMolecularFunctioncalcium ion binding

VLDLR LPCAT1 AOC1 ACTN4 ACTN1 ACTN3 NCAN EGFL7 DMP1 PCDH10

8.37e-0374911010GO:0005509
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIK4 GRIN2C GRIN2D

8.86e-03771103GO:0005230
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A1 SLC12A2

8.97e-03261102GO:0015296
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

GPM6A ATP6AP1 KCNH8 PSEN2 P2RY12 OTOP2 ACTN4 RNASEK GRIN2C GRIN2D TMBIM6 SLC4A1 SLC5A4 SLC6A1 LHCGR ADRB1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB ATP6AP2 APLNR SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

4.34e-14101710929GO:0098660
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GPM6A ATP6AP1 KCNH8 PSEN2 P2RY12 OTOP2 ACTN4 GRIK4 RNASEK GRIN2C GRIN2D TMBIM6 SLC4A1 SLC5A4 SLC6A1 LHCGR ADRB1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB ATP6AP2 APLNR SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

6.52e-14111510930GO:0034220
GeneOntologyBiologicalProcessmonoatomic ion transport

GPM6A ATP6AP1 KCNH8 PSEN2 P2RY12 OTOP2 ACTN4 GRIK4 RNASEK GRIN2C GRIN2D TMBIM6 SLC4A1 SLC5A4 SLC6A1 LHCGR ADRB1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB ATP6AP2 APLNR SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

1.34e-11137410930GO:0006811
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

GPM6A ATP6AP1 KCNH8 PSEN2 P2RY12 OTOP2 ACTN4 RNASEK GRIN2C GRIN2D TMBIM6 SLC5A4 SLC6A1 LHCGR ADRB1 SLC12A2 ATP6AP2 APLNR SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

6.66e-1192210924GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

GPM6A ATP6AP1 KCNH8 PSEN2 P2RY12 OTOP2 ACTN4 RNASEK GRIN2C GRIN2D TMBIM6 SLC5A4 SLC6A1 LHCGR ADRB1 SLC12A2 ATP6AP2 APLNR SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

1.03e-1094210924GO:0098655
GeneOntologyBiologicalProcessmonoatomic cation transport

GPM6A ATP6AP1 KCNH8 PSEN2 P2RY12 OTOP2 ACTN4 RNASEK GRIN2C GRIN2D TMBIM6 SLC5A4 SLC6A1 LHCGR ADRB1 SLC12A2 CLCNKB ATP6AP2 APLNR SCN7A OTOP1 SLC13A5 SLC47A1 TRPV3 ZDHHC13

1.22e-09115710925GO:0006812
GeneOntologyBiologicalProcessmetal ion transport

GPM6A KCNH8 PSEN2 P2RY12 ACTN4 GRIN2C GRIN2D TMBIM6 SLC5A4 SLC6A1 LHCGR ADRB1 SLC12A2 CLCNKB APLNR SCN7A SLC13A5 TRPV3 ZDHHC13

1.14e-06100010919GO:0030001
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

2.18e-061121097GO:1902476
GeneOntologyBiologicalProcessproton transmembrane transport

ATP6AP1 OTOP2 ACTN4 RNASEK SLC5A4 ATP6AP2 OTOP1 SLC47A1

3.38e-061701098GO:1902600
GeneOntologyBiologicalProcesschloride transport

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

5.30e-061281097GO:0006821
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

7.17e-061341097GO:0098661
GeneOntologyBiologicalProcesstransepithelial chloride transport

SLC12A2 CLCNKA CLCNKB

1.68e-05101093GO:0030321
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

1.70e-051531097GO:0098656
GeneOntologyBiologicalProcesspositive regulation of neurofibrillary tangle assembly

APOE CLU

2.77e-0521092GO:1902998
GeneOntologyBiologicalProcessvalyl-tRNA aminoacylation

VARS2 VARS1

2.77e-0521092GO:0006438
GeneOntologyBiologicalProcessinorganic anion import across plasma membrane

SLC6A1 SLC12A2

2.77e-0521092GO:0098658
GeneOntologyBiologicalProcessregulation of synapse organization

GPM6A VLDLR GHRL PSEN2 ADGRB2 ADGRB3 APOE AMIGO3 NCAN ST8SIA2

3.94e-0538710910GO:0050807
GeneOntologyBiologicalProcessGolgi lumen acidification

ATP6AP1 RNASEK ATP6AP2

3.95e-05131093GO:0061795
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

GPM6A PSEN2 P2RY12 GRIN2C GRIN2D TMBIM6 LHCGR ADRB1 APLNR TRPV3

4.39e-0539210910GO:0070588
GeneOntologyBiologicalProcessregulation of synapse structure or activity

GPM6A VLDLR GHRL PSEN2 ADGRB2 ADGRB3 APOE AMIGO3 NCAN ST8SIA2

4.68e-0539510910GO:0050803
GeneOntologyBiologicalProcessinorganic anion transport

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

4.83e-051801097GO:0015698
GeneOntologyBiologicalProcessendosomal lumen acidification

ATP6AP1 RNASEK ATP6AP2

5.01e-05141093GO:0048388
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC4A1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

5.37e-051831097GO:0006820
GeneOntologyBiologicalProcessregulation of neurofibrillary tangle assembly

APOE CLU

8.27e-0531092GO:1902996
GeneOntologyBiologicalProcesspositive regulation of synapse assembly

GHRL ADGRB2 ADGRB3 AMIGO3 ST8SIA2

9.31e-05861095GO:0051965
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

DRD5 ATP6AP1 PSEN2 RNASEK APOE TMBIM6 SLC4A1 LHCGR SLC12A2 ATP6AP2 APLNR SCN7A

9.38e-0561110912GO:0030003
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

DRD5 ATP6AP1 PSEN2 RNASEK APOE TMBIM6 SLC4A1 LHCGR SLC12A2 ATP6AP2 APLNR SCN7A

1.11e-0462210912GO:0006873
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

GRIN2C GRIN2D TMBIM6 LHCGR ADRB1 APLNR TRPV3

1.56e-042171097GO:0097553
GeneOntologyBiologicalProcessneurofibrillary tangle assembly

APOE CLU

1.65e-0441092GO:1902988
GeneOntologyBiologicalProcesscell junction organization

GPM6A VLDLR GHRL PSEN2 ADGRB2 ADGRB3 ACTN4 ACTN1 ACTN3 APOE SLC6A1 AMIGO3 NCAN APLNR ST8SIA2

1.85e-0497410915GO:0034330
GeneOntologyBiologicalProcesscell junction assembly

GPM6A VLDLR GHRL ADGRB2 ADGRB3 ACTN4 ACTN1 ACTN3 AMIGO3 APLNR ST8SIA2

2.14e-0456910911GO:0034329
GeneOntologyBiologicalProcesslysosomal lumen acidification

ATP6AP1 RNASEK ATP6AP2

2.68e-04241093GO:0007042
GeneOntologyBiologicalProcessresponse to abiotic stimulus

COL3A1 MAG VLDLR DRD5 ATP6AP1 GHRL PSEN2 PRPH2 INO80 GRIN2D PTAFR TMBIM6 TMEM87A ADRB1 SLC12A2 SCN7A OTOP1 TRPV3

2.68e-04136110918GO:0009628
GeneOntologyBiologicalProcesssynapse organization

GPM6A VLDLR GHRL PSEN2 ADGRB2 ADGRB3 ACTN1 APOE SLC6A1 AMIGO3 NCAN ST8SIA2

2.70e-0468510912GO:0050808
GeneOntologyBiologicalProcesspositive regulation of amyloid fibril formation

APOE CLU

2.74e-0451092GO:1905908
GeneOntologyBiologicalProcesschemical homeostasis

LPCAT1 DRD5 ATP6AP1 GHRL PSEN2 APOA5 RNASEK APOE TMBIM6 SLC4A1 LHCGR ADRB1 SLC12A2 ATP6AP2 APLNR SCN7A ADIPOR2

2.90e-04124910917GO:0048878
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

DRD5 ATP6AP1 PSEN2 RNASEK APOE TMBIM6 SLC4A1 LHCGR SLC12A2 ATP6AP2 APLNR SCN7A

3.51e-0470510912GO:0055080
GeneOntologyBiologicalProcesscalcium ion transport

GPM6A PSEN2 P2RY12 GRIN2C GRIN2D TMBIM6 LHCGR ADRB1 APLNR TRPV3

3.68e-0450910910GO:0006816
GeneOntologyBiologicalProcesspositive regulation of nervous system development

MAG GHRL ADGRB2 ADGRB3 APOE CLCN2 AMIGO3 NCAN ST8SIA2

3.78e-044181099GO:0051962
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIK4 GRIN2C GRIN2D

3.83e-04271093GO:0035235
GeneOntologyBiologicalProcessregulation of alcohol biosynthetic process

PTAFR APOE LHCGR CLCN2

3.90e-04651094GO:1902930
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

DRD5 ATP6AP1 PSEN2 RNASEK APOE TMBIM6 SLC4A1 LHCGR SLC12A2 ATP6AP2 APLNR SCN7A

4.08e-0471710912GO:0050801
GeneOntologyBiologicalProcesscognition

VLDLR DRD5 GHRL PSEN2 ADGRB3 APOE SLC6A1 LHCGR ADRB1

4.12e-044231099GO:0050890
GeneOntologyBiologicalProcesspositive regulation of small molecule metabolic process

APOA5 ACTN3 PTAFR APOE LHCGR LPGAT1

5.51e-041921096GO:0062013
GeneOntologyBiologicalProcesspositive regulation of transport

GHRL P2RY12 APOA5 ACTN4 PTAFR APOE SLC6A1 LHCGR ADRB1 SFTPA2 SLC12A2 CLU APLNR TRPV3 ADIPOR2

5.59e-04108110915GO:0051050
GeneOntologyBiologicalProcesspositive regulation of gastro-intestinal system smooth muscle contraction

GHRL PTAFR

5.71e-0471092GO:1904306
GeneOntologyBiologicalProcesspositive regulation of blood pressure by epinephrine-norepinephrine

DRD5 ADRB1

5.71e-0471092GO:0003321
GeneOntologyBiologicalProcessvery-low-density lipoprotein particle clearance

VLDLR APOE

5.71e-0471092GO:0034447
GeneOntologyBiologicalProcessregulation of lysosomal lumen pH

ATP6AP1 RNASEK ATP6AP2

6.37e-04321093GO:0035751
GeneOntologyBiologicalProcesssodium ion transport

ACTN4 SLC5A4 SLC6A1 SLC12A2 CLCNKB SCN7A SLC13A5

6.50e-042751097GO:0006814
GeneOntologyBiologicalProcessintracellular chemical homeostasis

DRD5 ATP6AP1 GHRL PSEN2 RNASEK APOE TMBIM6 SLC4A1 LHCGR SLC12A2 ATP6AP2 APLNR SCN7A

6.51e-0486610913GO:0055082
GeneOntologyBiologicalProcessregulation of synapse assembly

VLDLR GHRL ADGRB2 ADGRB3 AMIGO3 ST8SIA2

7.19e-042021096GO:0051963
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by norepinephrine-epinephrine

DRD5 ADRB1

7.59e-0481092GO:0001993
GeneOntologyBiologicalProcesspositive regulation of inclusion body assembly

APOE CLU

7.59e-0481092GO:0090261
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

DRD5 GHRL PSEN2 GRIK4 GRIN2C GRIN2D APOE SLC6A1 ADRB1 SLC12A2 NCAN

7.71e-0466310911GO:0050804
GeneOntologyBiologicalProcessphosphatidylcholine metabolic process

LPCAT1 TMEM86B SLC44A2 LPGAT1

7.79e-04781094GO:0046470
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

DRD5 GHRL PSEN2 GRIK4 GRIN2C GRIN2D APOE SLC6A1 ADRB1 SLC12A2 NCAN

7.80e-0466410911GO:0099177
GeneOntologyBiologicalProcesspositive regulation of cell junction assembly

GHRL ADGRB2 ADGRB3 AMIGO3 ST8SIA2

7.81e-041361095GO:1901890
GeneOntologyBiologicalProcesslearning or memory

VLDLR DRD5 GHRL PSEN2 ADGRB3 APOE SLC6A1 ADRB1

8.25e-043731098GO:0007611
GeneOntologyBiologicalProcesssodium ion transmembrane transport

ACTN4 SLC5A4 SLC6A1 SLC12A2 SCN7A SLC13A5

8.37e-042081096GO:0035725
GeneOntologyBiologicalProcessvacuolar acidification

ATP6AP1 RNASEK ATP6AP2

9.03e-04361093GO:0007035
GeneOntologyBiologicalProcessregulation of monoatomic cation transmembrane transport

PSEN2 ACTN4 GRIN2C GRIN2D TMBIM6 LHCGR ADRB1 APLNR

9.30e-043801098GO:1904062
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

PSEN2 P2RY12 ACTN4 GRIN2C GRIN2D TMBIM6 LHCGR ADRB1 APLNR TRPV3

9.69e-0457710910GO:0043269
GeneOntologyBiologicalProcessregulation of gastro-intestinal system smooth muscle contraction

GHRL PTAFR

9.72e-0491092GO:1904304
GeneOntologyBiologicalProcessphosphatidylglycerol acyl-chain remodeling

LPCAT1 LPGAT1

9.72e-0491092GO:0036148
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

DRD5 GHRL P2RY12 OR13C8 ADGRB2 ADGRB3 PTAFR APOE NPFFR1 LHCGR TAS2R3 ADRB1 GPR153 APLNR GPR156 OR10A6 OR56B4

1.02e-03139510917GO:0007186
GeneOntologyBiologicalProcesstransepithelial transport

SLC12A2 CLCNKA CLCNKB

1.06e-03381093GO:0070633
GeneOntologyBiologicalProcesslipoprotein metabolic process

APOA5 APOE HHAT ZDHHC13 PIGM

1.11e-031471095GO:0042157
GeneOntologyBiologicalProcessresponse to gravity

PTAFR OTOP1

1.21e-03101092GO:0009629
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIK4 GRIN2C GRIN2D

1.23e-03401093GO:1990806
GeneOntologyBiologicalProcesssynapse assembly

GPM6A VLDLR GHRL ADGRB2 ADGRB3 AMIGO3 ST8SIA2

1.26e-033081097GO:0007416
GeneOntologyBiologicalProcessregulation of cell junction assembly

VLDLR GHRL ADGRB2 ADGRB3 AMIGO3 APLNR ST8SIA2

1.28e-033091097GO:1901888
GeneOntologyBiologicalProcessregulation of cold-induced thermogenesis

OMA1 GHRL ACTN3 ADRB1 ADIPOR2

1.28e-031521095GO:0120161
GeneOntologyCellularComponenttransmembrane transporter complex

ATP6AP1 KCNH8 GRIK4 RNASEK GRIN2C GRIN2D CLCN1 CLCN2 CLCNKA CLCNKB ATP6AP2 SCN7A

2.65e-0552311312GO:1902495
GeneOntologyCellularComponenttransporter complex

ATP6AP1 KCNH8 GRIK4 RNASEK GRIN2C GRIN2D CLCN1 CLCN2 CLCNKA CLCNKB ATP6AP2 SCN7A

4.32e-0555011312GO:1990351
GeneOntologyCellularComponentmembrane protein complex

ATP6AP1 KCNH8 PSEN2 SLC38A9 GRIK4 RNASEK GRIN2C GRIN2D SSPOP SLC4A1 GJD4 CLCN1 CLCN2 CLCNKA CLCNKB ATP6AP2 SCN7A GPR156 TAP1 TRAV29DV5 TRAV13-2

4.73e-05149811321GO:0098796
GeneOntologyCellularComponentlipoprotein particle

VLDLR APOA5 APOE CLU

9.30e-05441134GO:1990777
GeneOntologyCellularComponentplasma lipoprotein particle

VLDLR APOA5 APOE CLU

9.30e-05441134GO:0034358
GeneOntologyCellularComponentpseudopodium

ACTN4 ACTN1 ACTN3

1.18e-04181133GO:0031143
GeneOntologyCellularComponentprotein-lipid complex

VLDLR APOA5 APOE CLU

1.21e-04471134GO:0032994
GeneOntologyCellularComponentglutamatergic synapse

GPM6A VLDLR DRD5 GHRL PSEN2 ADGRB2 ADGRB3 GRIK4 ACTN1 GRIN2C GRIN2D APOE NCAN PCDH10

1.32e-0481711314GO:0098978
GeneOntologyCellularComponentmonoatomic ion channel complex

KCNH8 GRIK4 GRIN2C GRIN2D CLCN1 CLCN2 CLCNKA CLCNKB SCN7A

2.15e-043781139GO:0034702
GeneOntologyCellularComponentextracellular matrix

A1BG COL3A1 PODNL1 LRRC3C APOE SSPOP SFTPA2 CLU NCAN EGFL7 DMP1 USH2A

2.27e-0465611312GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

A1BG COL3A1 PODNL1 LRRC3C APOE SSPOP SFTPA2 CLU NCAN EGFL7 DMP1 USH2A

2.33e-0465811312GO:0030312
GeneOntologyCellularComponentchloride channel complex

CLCN1 CLCN2 CLCNKA CLCNKB

2.56e-04571134GO:0034707
GeneOntologyCellularComponenttriglyceride-rich plasma lipoprotein particle

VLDLR APOA5 APOE

2.87e-04241133GO:0034385
GeneOntologyCellularComponentvery-low-density lipoprotein particle

VLDLR APOA5 APOE

2.87e-04241133GO:0034361
GeneOntologyCellularComponentsynaptic membrane

GPM6A DRD5 PSEN2 ADGRB3 GRIK4 GRIN2C GRIN2D SLC6A1 ATP6AP2 GPR156 PCDH10

3.22e-0458311311GO:0097060
GeneOntologyCellularComponentpostsynaptic membrane

DRD5 ADGRB3 GRIK4 GRIN2C GRIN2D SLC6A1 ATP6AP2 GPR156 PCDH10

3.56e-044051139GO:0045211
GeneOntologyCellularComponentvacuole

TMEM150B VLDLR LAPTM4A LPCAT1 ATP6AP1 SLC38A9 ACP5 SLC44A2 GNLY RNASEK ATP6AP2 NCAN TRPV3 WDFY3

4.10e-0491311314GO:0005773
GeneOntologyCellularComponentvacuolar membrane

TMEM150B VLDLR LAPTM4A LPCAT1 ATP6AP1 SLC38A9 SLC44A2 RNASEK ATP6AP2 WDFY3

4.30e-0450711310GO:0005774
GeneOntologyCellularComponentplatelet alpha granule lumen

A1BG ACTN4 ACTN1 CLU

4.77e-04671134GO:0031093
GeneOntologyCellularComponentproton-transporting V-type ATPase complex

ATP6AP1 RNASEK ATP6AP2

5.07e-04291133GO:0033176
GeneOntologyCellularComponentendoplasmic reticulum membrane

TMED1 LPCAT1 ATP6AP1 PSEN2 SLC27A6 TMEM86B GRIN2C GRIN2D TMBIM6 GBA2 SFTPA2 RNF103 ATP6AP2 HHAT LPGAT1 TAP1 PIGM

5.71e-04129311317GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

TMED1 LPCAT1 ATP6AP1 PSEN2 SLC27A6 TMEM86B GRIN2C GRIN2D TMBIM6 GBA2 SFTPA2 RNF103 ATP6AP2 HHAT LPGAT1 TAP1 PIGM

6.01e-04129911317GO:0098827
GeneOntologyCellularComponentcollagen-containing extracellular matrix

A1BG COL3A1 PODNL1 APOE SSPOP SFTPA2 CLU NCAN EGFL7 USH2A

6.06e-0453011310GO:0062023
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

TMED1 LPCAT1 ATP6AP1 PSEN2 SLC27A6 TMEM86B GRIN2C GRIN2D TMBIM6 GBA2 SFTPA2 RNF103 ATP6AP2 HHAT LPGAT1 TAP1 PIGM

7.63e-04132711317GO:0042175
GeneOntologyCellularComponenthigh-density lipoprotein particle

APOA5 APOE CLU

8.87e-04351133GO:0034364
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2C GRIN2D

1.02e-0391132GO:0017146
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase, V0 domain

RNASEK ATP6AP2

1.27e-03101132GO:0000220
GeneOntologyCellularComponentZ disc

PSEN2 ACTN4 ACTN1 ACTN3 SLC4A1

1.38e-031511135GO:0030018
GeneOntologyCellularComponentlysosome

VLDLR LAPTM4A LPCAT1 ATP6AP1 SLC38A9 ACP5 SLC44A2 GNLY RNASEK ATP6AP2 NCAN TRPV3

1.46e-0381111312GO:0005764
GeneOntologyCellularComponentlytic vacuole

VLDLR LAPTM4A LPCAT1 ATP6AP1 SLC38A9 ACP5 SLC44A2 GNLY RNASEK ATP6AP2 NCAN TRPV3

1.46e-0381111312GO:0000323
GeneOntologyCellularComponentcell body

GPM6A DRD5 PSEN2 TMEM50A P2RY12 GRIK4 APOE SLC6A1 CLCN2 SLC12A2 ATP6AP2 WDFY3 USH2A

1.53e-0392911313GO:0044297
GeneOntologyCellularComponentplatelet alpha granule

A1BG ACTN4 ACTN1 CLU

1.63e-03931134GO:0031091
GeneOntologyCellularComponentpostsynaptic density membrane

DRD5 ADGRB3 GRIK4 GRIN2C GRIN2D

1.64e-031571135GO:0098839
GeneOntologyCellularComponentproton-transporting V-type ATPase, V0 domain

RNASEK ATP6AP2

1.85e-03121132GO:0033179
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIK4 GRIN2C GRIN2D

1.85e-03451133GO:0008328
GeneOntologyCellularComponentsecretory granule lumen

A1BG AOC1 GHRL PSMD2 ACTN4 ACTN1 CLU

1.95e-033251137GO:0034774
GeneOntologyCellularComponentI band

PSEN2 ACTN4 ACTN1 ACTN3 SLC4A1

2.09e-031661135GO:0031674
GeneOntologyCellularComponentglial cell projection

TMEM50A CLCN2 SCN7A

2.10e-03471133GO:0097386
GeneOntologyCellularComponentcytoplasmic vesicle lumen

A1BG AOC1 GHRL PSMD2 ACTN4 ACTN1 CLU

2.12e-033301137GO:0060205
GeneOntologyCellularComponentchylomicron

APOA5 APOE

2.17e-03131132GO:0042627
GeneOntologyCellularComponentvesicle lumen

A1BG AOC1 GHRL PSMD2 ACTN4 ACTN1 CLU

2.20e-033321137GO:0031983
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6AP1 RNASEK ATP6AP2

2.36e-03491133GO:0090533
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIK4 GRIN2C GRIN2D

2.51e-03501133GO:0098878
GeneOntologyCellularComponentsecretory vesicle

A1BG LPCAT1 ATP6AP1 AOC1 GHRL PSEN2 SLC44A2 PSMD2 ACTN4 ACTN1 PTAFR ADRB1 SFTPA2 CLU ATP6AP2

2.90e-03124611315GO:0099503
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex

ATP6AP1 RNASEK ATP6AP2

2.96e-03531133GO:0016469
GeneOntologyCellularComponentbasal plasma membrane

P2RY12 SLC4A1 CLCN2 SLC12A2 CLCNKA SLC13A5 SLC47A1

3.14e-033541137GO:0009925
GeneOntologyCellularComponentsecretory granule

A1BG LPCAT1 AOC1 GHRL SLC44A2 PSMD2 ACTN4 ACTN1 PTAFR ADRB1 SFTPA2 CLU ATP6AP2

3.28e-03101411313GO:0030141
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP6AP1 RNASEK ATP6AP2

3.29e-03551133GO:0098533
GeneOntologyCellularComponentlow-density lipoprotein particle

APOA5 APOE

3.31e-03161132GO:0034362
GeneOntologyCellularComponentpostsynapse

GPM6A DRD5 GHRL ADGRB3 ACTN4 GRIK4 ACTN1 GRIN2C GRIN2D SLC6A1 ATP6AP2 GPR156 PCDH10

3.39e-03101811313GO:0098794
GeneOntologyCellularComponentdense core granule

GHRL ACTN1 ADRB1

3.46e-03561133GO:0031045
GeneOntologyCellularComponentlysosomal membrane

VLDLR LAPTM4A LPCAT1 ATP6AP1 SLC38A9 SLC44A2 RNASEK ATP6AP2

3.63e-034621138GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

VLDLR LAPTM4A LPCAT1 ATP6AP1 SLC38A9 SLC44A2 RNASEK ATP6AP2

3.63e-034621138GO:0098852
GeneOntologyCellularComponentautophagosome membrane

TMEM150B ATP6AP2 WDFY3

3.64e-03571133GO:0000421
GeneOntologyCellularComponentendosome

TMEM150B LAPTM4A ATP6AP1 PSEN2 APOA5 SLC38A9 RNF149 RNASEK APOE LHCGR ADRB1 SFTPA2 ATP6AP2 ST8SIA2

4.14e-03116711314GO:0005768
GeneOntologyCellularComponentreceptor complex

VLDLR GRIK4 GRIN2C GRIN2D LHCGR GPR156 TRPV3 TRAV29DV5 TRAV13-2

4.30e-035811139GO:0043235
GeneOntologyCellularComponentbasal part of cell

P2RY12 SLC4A1 CLCN2 SLC12A2 CLCNKA SLC13A5 SLC47A1

4.49e-033781137GO:0045178
GeneOntologyCellularComponentpostsynaptic specialization membrane

DRD5 ADGRB3 GRIK4 GRIN2C GRIN2D

4.75e-032011135GO:0099634
GeneOntologyCellularComponentcortical cytoskeleton

ACTN4 ACTN1 ACTN3 SLC4A1

5.31e-031291134GO:0030863
GeneOntologyCellularComponentATPase complex

ATP6AP1 RNASEK INO80 ATP6AP2

5.31e-031291134GO:1904949
GeneOntologyCellularComponentneuronal cell body

GPM6A DRD5 PSEN2 TMEM50A GRIK4 APOE SLC6A1 CLCN2 SLC12A2 WDFY3 USH2A

5.55e-0383511311GO:0043025
GeneOntologyCellularComponentGolgi membrane

LPCAT1 ATP6AP1 PSEN2 RNASEK GBA2 TMEM87A ATP6AP2 HHAT ST8SIA2 ZDHHC13

5.72e-0372111310GO:0000139
GeneOntologyCellularComponentsomatodendritic compartment

GPM6A DRD5 PSEN2 TMEM50A GRIK4 ACTN1 APOE SLC6A1 CLCN2 SLC12A2 CLU ATP6AP2 WDFY3 USH2A

6.44e-03122811314GO:0036477
GeneOntologyCellularComponentblood microparticle

A1BG APOE SLC4A1 CLU

7.79e-031441134GO:0072562
GeneOntologyCellularComponentbasolateral plasma membrane

SLC4A1 CLCN2 SLC12A2 CLCNKA SLC13A5 SLC47A1

7.90e-033201136GO:0016323
GeneOntologyCellularComponentendocytic vesicle lumen

GNLY APOE

8.01e-03251132GO:0071682
GeneOntologyCellularComponentclathrin-coated vesicle membrane

ATP6AP1 RNASEK APOE ATP6AP2

8.36e-031471134GO:0030665
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase complex

RNASEK ATP6AP2

8.65e-03261132GO:0016471
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex, proton-transporting domain

RNASEK ATP6AP2

8.65e-03261132GO:0033177
GeneOntologyCellularComponentclathrin-coated vesicle

ATP6AP1 RNASEK APOE SFTPA2 ATP6AP2

9.36e-032371135GO:0030136
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL3A1 GHRL APOA5 APOE CLU DMP1

9.38e-033321136GO:0005788
GeneOntologyCellularComponentendoplasmic reticulum-Golgi intermediate compartment membrane

TMED1 ATP6AP1 TAP1

9.67e-03811133GO:0033116
GeneOntologyCellularComponentplasma membrane protein complex

PSEN2 GRIK4 GRIN2C GRIN2D SSPOP GJD4 SCN7A GPR156 TRAV29DV5 TRAV13-2

1.01e-0278511310GO:0098797
GeneOntologyCellularComponentsodium channel complex

GRIK4 SCN7A

1.07e-02291132GO:0034706
GeneOntologyCellularComponentcytoplasmic vesicle membrane

TMEM150B LAPTM4A LPCAT1 ATP6AP1 SLC38A9 SLC44A2 RNASEK ACTN1 PTAFR APOE SLC12A2 ATP6AP2 ZDHHC13 TAP1

1.08e-02130711314GO:0030659
GeneOntologyCellularComponentsarcomere

PSEN2 ACTN4 ACTN1 ACTN3 SLC4A1

1.14e-022491135GO:0030017
GeneOntologyCellularComponentlate endosome

LAPTM4A APOA5 SLC38A9 RNF149 APOE SFTPA2

1.16e-023481136GO:0005770
GeneOntologyCellularComponentplasma membrane signaling receptor complex

GRIK4 GRIN2C GRIN2D GPR156 TRAV29DV5 TRAV13-2

1.19e-023501136GO:0098802
GeneOntologyCellularComponentvesicle membrane

TMEM150B LAPTM4A LPCAT1 ATP6AP1 SLC38A9 SLC44A2 RNASEK ACTN1 PTAFR APOE SLC12A2 ATP6AP2 ZDHHC13 TAP1

1.21e-02132511314GO:0012506
DomainCl-channel_core

CLCN1 CLCN2 CLCNKA CLCNKB

1.46e-0791114IPR014743
Domain-

CLCN1 CLCN2 CLCNKA CLCNKB

1.46e-07911141.10.3080.10
DomainVoltage_CLC

CLCN1 CLCN2 CLCNKA CLCNKB

1.46e-0791114PF00654
DomainCl-channel_volt-gated

CLCN1 CLCN2 CLCNKA CLCNKB

1.46e-0791114IPR001807
DomainEF-hand_Ca_insen

ACTN4 ACTN1 ACTN3

4.03e-0661113IPR014837
DomainEFhand_Ca_insen

ACTN4 ACTN1 ACTN3

4.03e-0661113PF08726
DomainCBS_dom

CLCN1 CLCN2 CLCNKA CLCNKB

5.32e-06201114IPR000644
DomainCBS

CLCN1 CLCN2 CLCNKA CLCNKB

5.32e-06201114PF00571
DomainCBS

CLCN1 CLCN2 CLCNKA CLCNKB

5.32e-06201114PS51371
DomainValyl-tRNA_ligase

VARS2 VARS1

3.50e-0521112IPR002303
DomainAnticodon_Ia_Val

VARS2 VARS1

3.50e-0521112IPR033705
DomainCl_channel-K

CLCNKA CLCNKB

3.50e-0521112IPR002250
DomainGPCR_2_brain_angio_inhib

ADGRB2 ADGRB3

1.05e-0431112IPR008077
DomainApolipoprotein

APOA5 APOE

1.05e-0431112PF01442
DomainOtopetrin

OTOP2 OTOP1

1.05e-0431112PF03189
DomainApoA_E

APOA5 APOE

1.05e-0431112IPR000074
DomainOtopetrin

OTOP2 OTOP1

1.05e-0431112IPR004878
DomainCBS

CLCN2 CLCNKA CLCNKB

1.08e-04161113SM00116
DomainIontro_rcpt

GRIK4 GRIN2C GRIN2D

1.56e-04181113IPR001320
DomainLig_chan-Glu_bd

GRIK4 GRIN2C GRIN2D

1.56e-04181113PF10613
DomainIono_rcpt_met

GRIK4 GRIN2C GRIN2D

1.56e-04181113IPR001508
DomainGlu/Gly-bd

GRIK4 GRIN2C GRIN2D

1.56e-04181113IPR019594
DomainLig_chan-Glu_bd

GRIK4 GRIN2C GRIN2D

1.56e-04181113SM00918
DomainLig_chan

GRIK4 GRIN2C GRIN2D

1.56e-04181113PF00060
DomainPBPe

GRIK4 GRIN2C GRIN2D

1.56e-04181113SM00079
DomainActinin_actin-bd_CS

ACTN4 ACTN1 ACTN3

3.32e-04231113IPR001589
DomainSpectrin

ACTN4 ACTN1 ACTN3

3.32e-04231113PF00435
DomainACTININ_2

ACTN4 ACTN1 ACTN3

3.32e-04231113PS00020
DomainACTININ_1

ACTN4 ACTN1 ACTN3

3.32e-04231113PS00019
DomainVal/Leu/Ile-tRNA-synth_edit

VARS2 VARS1

5.17e-0461112IPR009008
DomainAnticodon_1

VARS2 VARS1

5.17e-0461112PF08264
DomainM/V/L/I-tRNA-synth_anticd-bd

VARS2 VARS1

5.17e-0461112IPR013155
Domain-

VARS2 VARS1

5.17e-04611123.90.740.10
DomainSpectrin_repeat

ACTN4 ACTN1 ACTN3

6.67e-04291113IPR002017
Domainaa-tRNA-synth_Ia

VARS2 VARS1

7.21e-0471112IPR002300
DomaintRNA-synt_1

VARS2 VARS1

7.21e-0471112PF00133
DomainGPCR_Rhodpsn

DRD5 P2RY12 OR13C8 PTAFR NPFFR1 LHCGR TAS2R3 ADRB1 GPR153 APLNR OR10A6 OR56B4

8.41e-0469211112IPR000276
DomainSpectrin/alpha-actinin

ACTN4 ACTN1 ACTN3

8.94e-04321113IPR018159
DomainSPEC

ACTN4 ACTN1 ACTN3

8.94e-04321113SM00150
DomainANF_lig-bd_rcpt

GRIK4 GRIN2C GRIN2D

1.37e-03371113IPR001828
DomainANF_receptor

GRIK4 GRIN2C GRIN2D

1.37e-03371113PF01094
DomainPeripla_BP_I

GRIK4 GRIN2C GRIN2D

1.60e-03391113IPR028082
DomainGAIN_dom_N

ADGRB2 ADGRB3

1.86e-03111112IPR032471
Domain-

VARS2 VARS1

1.86e-031111121.10.730.10
DomainGAIN

ADGRB2 ADGRB3

1.86e-03111112PF16489
DomainGPCR_Rhodpsn_7TM

DRD5 P2RY12 OR13C8 PTAFR NPFFR1 LHCGR ADRB1 GPR153 APLNR OR10A6 OR56B4

2.14e-0367011111IPR017452
Domain7tm_1

DRD5 P2RY12 OR13C8 PTAFR NPFFR1 LHCGR ADRB1 GPR153 APLNR OR10A6 OR56B4

2.32e-0367711111PF00001
DomainG_PROTEIN_RECEP_F1_1

DRD5 P2RY12 OR13C8 PTAFR NPFFR1 LHCGR ADRB1 GPR153 APLNR OR10A6 OR56B4

2.54e-0368511111PS00237
DomainG_PROTEIN_RECEP_F1_2

DRD5 P2RY12 OR13C8 PTAFR NPFFR1 LHCGR ADRB1 GPR153 APLNR OR10A6 OR56B4

2.72e-0369111111PS50262
DomainLRRNT

PODNL1 LRRC3C LHCGR AMIGO3

2.78e-03981114IPR000372
DomainLRRNT

PODNL1 LRRC3C LHCGR AMIGO3

2.78e-03981114SM00013
DomaintRNAsynth_Ia_anticodon-bd

VARS2 VARS1

3.49e-03151112IPR009080
DomainAcyltransferase

LPCAT1 LPGAT1

3.98e-03161112PF01553
DomainEGF_1

VLDLR MUC3B SSPOP NCAN EGFL7 USH2A

4.19e-032551116PS00022
DomainPlsC

LPCAT1 LPGAT1

4.49e-03171112SM00563
DomainEMI

SSPOP EGFL7

4.49e-03171112PS51041
DomainPlipid/glycerol_acylTrfase

LPCAT1 LPGAT1

4.49e-03171112IPR002123
Domainaa-tRNA-synth_I_CS

VARS2 VARS1

5.03e-03181112IPR001412
DomainAA_TRNA_LIGASE_I

VARS2 VARS1

5.60e-03191112PS00178
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

VLDLR ATP6AP1 SLC27A6 APOA5 SLC44A2 PSMD2 APOE SLC4A1 SLC5A4 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB LCN15 SLC13A5 SLC47A1 TRPV3

1.79e-077369119M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

VLDLR ATP6AP1 SLC27A6 APOA5 SLC44A2 PSMD2 APOE SLC4A1 SLC5A4 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SLC13A5 SLC47A1 TRPV3

2.82e-076819118MM14985
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

DRD5 GRIK4 GRIN2C GRIN2D PTAFR NPFFR1 LHCGR ADRB1 APLNR GPR156

9.85e-062729110M13380
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC27A6 SLC44A2 SLC4A1 SLC5A4 SLC6A1 SLC12A2 LCN15 SLC13A5 SLC47A1

3.22e-05249919M5988
PathwayWP_GPCRS_NONODORANT

DRD5 P2RY12 ADGRB2 ADGRB3 PTAFR LHCGR TAS2R3 ADRB1 APLNR

5.38e-05266919MM15843
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC27A6 SLC44A2 SLC4A1 SLC5A4 SLC6A1 SLC12A2 SLC13A5 SLC47A1

1.49e-04238918MM15076
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

DRD5 GHRL P2RY12 RLN3 PTAFR NPFFR1 LHCGR ADRB1 APLNR

2.75e-04330919M18334
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2C GRIN2D

4.07e-045912M47667
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

GRIN2C GRIN2D

4.07e-045912MM15655
PathwayREACTOME_NEPHRIN_FAMILY_INTERACTIONS

ACTN4 ACTN1 ACTN3

4.20e-0423913M913
PathwayREACTOME_STIMULI_SENSING_CHANNELS

CLCN1 CLCN2 CLCNKA CLCNKB TRPV3

4.45e-0499915MM14910
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2C GRIN2D

6.08e-046912M47668
PathwayREACTOME_STIMULI_SENSING_CHANNELS

CLCN1 CLCN2 CLCNKA CLCNKB TRPV3

6.09e-04106915M27200
Pubmed

Changing expression of chloride channels during preimplantation mouse development.

CLCN1 CLCN2 CLCNKA CLCNKB

1.36e-089114423115349
Pubmed

α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.

ACTN4 ACTN1 ACTN3

3.43e-083114321784188
Pubmed

Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.

ACTN4 ACTN1 ACTN3

1.37e-07411431629252
Pubmed

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.

ACTN4 ACTN1 ACTN3

1.37e-074114316807302
Pubmed

Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks.

APOE ADRB1 SCN7A

1.37e-074114317339538
Pubmed

Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.

MAG ACTN4 ACTN1 ACTN3

1.45e-0715114411440986
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

DRD5 ADGRB2 ADGRB3 NPFFR1 GPR153 GPR156

2.48e-0779114612679517
Pubmed

Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.

ACTN4 ACTN1 ACTN3

3.41e-075114315841212
Pubmed

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.

ACTN4 ACTN1 ACTN3

3.41e-075114312837758
Pubmed

ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor.

VLDLR LPCAT1 PTAFR

3.41e-075114332140075
Pubmed

Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.

ACTN4 ACTN1 ACTN3

3.41e-075114319943616
Pubmed

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

ACTN4 ACTN1 ACTN3

6.81e-076114318425115
Pubmed

The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.

ACTN4 ACTN1 ACTN3

6.81e-076114322693585
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

ATP6AP1 SLC38A9 SLC44A2 MFSD9 TMEM87A GJD4 PIK3IP1 ATP6AP2 APLNR PIGM

1.63e-064301141016303743
Pubmed

Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.

PSEN2 LIPF ACTN4 ACTN1 APOE CLU

1.86e-06111114621163940
Pubmed

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.

ACTN4 ACTN1 ACTN3

1.90e-068114320215401
Pubmed

Mice deficient in alpha-actinin-4 have severe glomerular disease.

ACTN4 ACTN1 ACTN3

1.90e-068114312782671
Pubmed

Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.

DRD5 OTOP2 OTOP1

1.90e-068114312651873
Pubmed

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

VLDLR APOE A2ML1

2.84e-06911437544347
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

VLDLR APOE CLU

2.84e-069114320005821
Pubmed

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.

ACTN4 ACTN1 ACTN3

4.05e-0610114320368620
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

KCNH8 CLCN1 CLCN2 CLCNKA CLCNKB SCN7A

6.84e-06139114616985003
Pubmed

Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.

ACTN4 ACTN1 ACTN3

7.38e-0612114315465019
Pubmed

An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.

ADGRB2 ADGRB3 ACTN1 GRIN2C ADRB1

8.70e-0684114515123239
Pubmed

Structure and Roles of V-type ATPases.

ATP6AP1 RNASEK ATP6AP2

9.58e-0613114332001091
Pubmed

A common VLDLR polymorphism interacts with APOE genotype in the prediction of carotid artery disease risk.

VLDLR APOE

1.07e-052114218056683
Pubmed

Apolipoprotein polymorphism is associated with pro-thrombotic profile in non-demented dyslipidemic subjects.

APOA5 APOE

1.07e-052114225073959
Pubmed

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

CLCNKA CLCNKB

1.07e-052114227335120
Pubmed

Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.

CLCNKA CLCNKB

1.07e-05211428812470
Pubmed

Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.

CLCNKA CLCNKB

1.07e-052114225919862
Pubmed

Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors.

ATP6AP1 ATP6AP2

1.07e-052114230166553
Pubmed

An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.

ACTN4 ACTN1

1.07e-052114223557398
Pubmed

Interaction between APOA5 -1131T>C and APOE polymorphisms and their association with severe hypertriglyceridemia.

APOA5 APOE

1.07e-052114218549811
Pubmed

Synergistic Effects of APOE and CLU May Increase the Risk of Alzheimer's Disease: Acceleration of Atrophy in the Volumes and Shapes of the Hippocampus and Amygdala.

APOE CLU

1.07e-052114233682707
Pubmed

Expression of brain-specific angiogenesis inhibitor 2 (BAI2) in normal and ischemic brain: involvement of BAI2 in the ischemia-induced brain angiogenesis.

ADGRB2 ADGRB3

1.07e-052114212218411
Pubmed

Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.

CLCNKA CLCNKB

1.07e-052114238069401
Pubmed

Sex-specific interaction between APOE and APOA5 variants and determination of plasma lipid levels.

APOA5 APOE

1.07e-052114217957227
Pubmed

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.

CLCNKA CLCNKB

1.07e-052114220805576
Pubmed

Genetic association of APOA5 and APOE with metabolic syndrome and their interaction with health-related behavior in Korean men.

APOA5 APOE

1.07e-052114226365620
Pubmed

Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro.

APOE CLU

1.07e-052114224446231
Pubmed

Genetic variants of apolipoprotein A5 T-1131C and apolipoprotein E common polymorphisms and their relationship to features of metabolic syndrome in adult dyslipidemic patients.

APOA5 APOE

1.07e-052114224709297
Pubmed

Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells.

ACTN4 ACTN1

1.07e-052114220156433
Pubmed

Polymorphisms in apolipoprotein E and apolipoprotein A-V do not influence the lipid response to rosuvastatin but are associated with baseline lipid levels in Chinese patients with hyperlipidemia.

APOA5 APOE

1.07e-052114223312054
Pubmed

The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort.

APOE CLU

1.07e-052114227076484
Pubmed

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

GRIN2C GRIN2D

1.07e-052114229317596
Pubmed

A combined effect of two Alzheimer's risk genes on medial temporal activity during executive attention in young adults.

APOE CLU

1.07e-052114224388797
Pubmed

Apolipoprotein A5-1131T>C polymorphism, but not APOE genotypes, increases susceptibility for dyslipidemia in children and adolescents.

APOA5 APOE

1.07e-052114221132386
Pubmed

Combined effects of Alzheimer risk variants in the CLU and ApoE genes on ventricular expansion patterns in the elderly.

APOE CLU

1.07e-052114224806679
Pubmed

NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.

GRIN2C GRIN2D

1.07e-052114233766086
Pubmed

Atheroprotective effect of human apolipoprotein A5 in a mouse model of mixed dyslipidemia.

APOA5 APOE

1.07e-052114218658049
Pubmed

Salt wasting and deafness resulting from mutations in two chloride channels.

CLCNKA CLCNKB

1.07e-052114215044642
Pubmed

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

CLCNKA CLCNKB

1.07e-05211428041726
Pubmed

A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.

CLCNKA CLCNKB

1.07e-052114218648499
Pubmed

Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.

CLCNKA CLCNKB

1.07e-05211428544406
Pubmed

The association of the regulatory region of the presenilin-2 gene with Alzheimer's disease in the Northern Han Chinese population.

PSEN2 APOE

1.07e-052114217727891
Pubmed

TAP1-deficiency does not alter atherosclerosis development in Apoe-/- mice.

APOE TAP1

1.07e-052114222479479
Pubmed

The influence of the S19W SNP of the APOA5 gene on triglyceride levels in southern Brazil: interactions with the APOE gene, sex and menopause status.

APOA5 APOE

1.07e-052114220304614
Pubmed

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.

GRIN2C GRIN2D

1.07e-052114229651654
Pubmed

Examining the effects of the CLU and APOE polymorphisms' combination on coronary artery disease complexed with type 2 diabetes mellitus.

APOE CLU

1.07e-052114234686405
Pubmed

Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice.

APOE ADRB1

1.07e-052114237235594
Pubmed

Two polymorphisms of presenilin-2 gene (PSEN2) 5' regulatory region are not associated with Alzheimer's disease (AD) in the Polish population.

PSEN2 APOE

1.07e-052114218087668
Pubmed

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.

GRIN2C GRIN2D

1.07e-052114231110197
Pubmed

Transcriptional down-regulation of the platelet ADP receptor P2Y(12) and clusterin in patients with systemic lupus erythematosus.

P2RY12 CLU

1.07e-052114215304052
Pubmed

Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking.

ACTN4 ACTN1

1.07e-052114234010028
Pubmed

ApoE and clusterin CSF levels influence associations between APOE genotype and changes in CSF tau, but not CSF Aβ42, levels in non-demented elderly.

APOE CLU

1.07e-052114231029938
Pubmed

Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.

CLCNKA CLCNKB

1.07e-052114224863058
Pubmed

Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

CLCNKA CLCNKB

1.07e-05211429916798
Pubmed

Kidney kinetics and chloride ion pumps.

CLCNKA CLCNKB

1.07e-05211429916791
Pubmed

Polymorphism of the regulatory region of the presenilin-2 gene in sporadic Alzheimer's disease: a case-control study.

PSEN2 APOE

1.07e-052114216233903
Pubmed

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.

GRIN2C GRIN2D

1.07e-052114235057644
Pubmed

Activation of the LH receptor up regulates the type 2 adiponectin receptor in human granulosa cells.

LHCGR ADIPOR2

1.07e-052114223779096
Pubmed

Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults.

APOE CLU

1.07e-052114226343804
Pubmed

Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.

ACTN4 ACTN1

1.07e-052114220037648
Pubmed

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.

APOE CLU

1.07e-052114214741101
Pubmed

HAMLET binding to α-actinin facilitates tumor cell detachment.

ACTN4 ACTN1

1.07e-052114221408150
Pubmed

Transmembrane BAX inhibitor motif containing 6 suppresses presenilin-2 to preserve mitochondrial integrity after myocardial ischemia-reperfusion injury.

PSEN2 TMBIM6

1.07e-052114236923943
Pubmed

Enhanced platelet reactivity and thrombosis in Apoe-/- mice exposed to cigarette smoke is attenuated by P2Y12 antagonism.

P2RY12 APOE

1.07e-052114220451958
Pubmed

Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells.

ACTN4 ACTN1

1.07e-052114228797528
Pubmed

Enhancement of the binding of triglyceride-rich lipoproteins to the very low density lipoprotein receptor by apolipoprotein E and lipoprotein lipase.

VLDLR APOE

1.07e-05211427797576
Pubmed

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

GRIN2C GRIN2D

1.07e-052114231786200
Pubmed

Apolipoprotein E and clusterin inhibit the early phase of amyloid-β aggregation in an in vitro model of cerebral amyloid angiopathy.

APOE CLU

1.07e-052114230691533
Pubmed

α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.

ACTN4 ACTN1

1.07e-052114223454549
Pubmed

Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults.

APOE CLU

1.07e-052114227143425
Pubmed

Polymorphisms in the apolipoprotein A5 (APOA5) gene and type III hyperlipidemia.

APOA5 APOE

1.07e-052114216143024
Pubmed

Vessel wall, not platelet, P2Y12 potentiates early atherogenesis.

P2RY12 APOE

1.07e-052114224510394
Pubmed

Genetic variants in PSEN2 and correlation to CSF β-amyloid42 levels in AD.

PSEN2 APOE

1.07e-052114220850903
Pubmed

Downregulation of Apolipoprotein-E and Apolipoprotein-J in Moyamoya Disease-A Proteome Analysis of Cerebrospinal Fluid.

APOE CLU

1.07e-052114228843803
Pubmed

Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.

CLCNKA CLCNKB

1.07e-052114211014860
Pubmed

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

SLC44A2 PSMD2 ACTN4 APOE CLU

1.36e-0592114523055941
Pubmed

Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes.

DRD5 PSEN2 APOE

1.52e-0515114320468060
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

COL3A1 APOE CLU EGFL7

2.24e-0550114423658023
Pubmed

Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

ATP6AP1 RNASEK ATP6AP2

2.26e-0517114333065002
Pubmed

Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.

CLCNKA CLCNKB

3.19e-053114226013830
Pubmed

Genes, fat intake, and cardiovascular disease risk factors in the Quebec Family Study.

GHRL APOE

3.19e-053114217890503
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2C GRIN2D

3.19e-05311429718984
Pubmed

Barttin increases surface expression and changes current properties of ClC-K channels.

CLCNKA CLCNKB

3.19e-053114212111250
Pubmed

Apolipoprotein J/clusterin in human erythrocytes is involved in the molecular process of defected material disposal during vesiculation.

SLC4A1 CLU

3.19e-053114222016805
Pubmed

Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study.

APOA5 APOE

3.19e-053114220429872
Pubmed

AMPA, NMDA and kainate glutamate receptor subunits are expressed in human peripheral blood mononuclear cells (PBMCs) where the expression of GluK4 is altered by pregnancy and GluN2D by depression in pregnant women.

GRIK4 GRIN2D

3.19e-053114228284346
Pubmed

Genetic characterization of physical activity behaviours in university students enrolled in kinesiology degree programs.

ACTN3 ADRB1

3.19e-053114228177749
GeneFamilyChloride voltage-gated channels

CLCN1 CLCN2 CLCNKA CLCNKB

8.08e-0810824302
GeneFamilyActinins

ACTN4 ACTN1 ACTN3

3.59e-0748231112
GeneFamilyAdhesion G protein-coupled receptors, subfamily B

ADGRB2 ADGRB3

6.08e-053822912
GeneFamilySolute carriers

SLC27A6 SLC38A9 SLC44A2 SLC4A1 SLC5A4 SLC6A1 SLC12A2 SLC13A5 SLC47A1

7.43e-05395829752
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2C GRIN2D

4.20e-0478221201
GeneFamilyAminoacyl tRNA synthetases, Class I

VARS2 VARS1

3.30e-0319822131
GeneFamilyApolipoproteins

APOA5 APOE

4.03e-0321822405
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A GRIN2C SLC6A1 LHCGR CLU NCAN SLC13A5 PCDH10

2.59e-081861138ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6AP1 APOE TMBIM6 SLC4A1 ADRB1 CLCNKA CLCNKB ATP6AP2

3.18e-0819111388b34e06c398056e857a10c7653c70c0b1f181692
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A GRIN2C APOE SLC6A1 CLU NCAN SLC13A5 PCDH10

3.32e-081921138d2161842a38146261847fc9061ba9322e0f087e0
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL3A1 PODNL1 VLDLR SLC27A6 APOE APLNR EGFL7

2.68e-0717011377fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2C APOE SLC6A1 CLU NCAN GPR156 SLC13A5

3.39e-071761137ac3dc44755280e36c0947b6de3cd639dc17de8b6
ToppCellCaecum-(7)_Mast_cell|Caecum / shred on region, Cell_type, and subtype

MAG LAPTM4A PTAFR APOE CLU SCN7A IL1RL1

8.01e-072001137d23fe8644ce42ace51fcde43cb4cd22a99300c02
ToppCellCaecum-Mast_cell|Caecum / Region, Cell class and subclass

MAG LAPTM4A PTAFR APOE CLU SCN7A IL1RL1

8.01e-0720011378791d0b3d883e7a747a23d21118817f5be4013b6
ToppCellCaecum-(7)_Mast_cell-(70)_Mast|Caecum / shred on region, Cell_type, and subtype

MAG LAPTM4A PTAFR APOE CLU SCN7A IL1RL1

8.01e-0720011379974285c28a633a010c4f24d035ad3685705e881
ToppCellCaecum-Mast_cell-Mast|Caecum / Region, Cell class and subclass

MAG LAPTM4A PTAFR APOE CLU SCN7A IL1RL1

8.01e-072001137168426e8296697d05684d71989c4eb5bb2a0489f
ToppCellP28-Hematopoietic-Erythroid|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GBA2 SLC4A1 TUBGCP6 HHAT ZDHHC13

2.27e-06831135e548e5c7b16c895b360a00f3d6fc1a7eb3d19294
ToppCellP28-Hematopoietic-Erythroid-enucleate_erythrocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GBA2 SLC4A1 TUBGCP6 HHAT ZDHHC13

2.27e-06831135c7ff56d4c7582fc497057cf3d5497fbd13c183cc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 APOE TMBIM6 SLC5A4 APLNR EGFL7

3.78e-06163113673c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAG ADGRB2 GRIN2C CLU IL1RL1 EGFL7

4.20e-061661136c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell10x5'-GI_large-bowel-Mast|GI_large-bowel / Manually curated celltypes from each tissue

MAG LAPTM4A PTAFR CLU SCN7A IL1RL1

6.27e-061781136d10ed2543c96e1a2373f847e0b82144771e26d07
ToppCell10x5'-GI_large-bowel-Mast-Mast_cells|GI_large-bowel / Manually curated celltypes from each tissue

MAG LAPTM4A PTAFR CLU SCN7A IL1RL1

6.27e-0617811368fc5f735afa25ae43c2acb1c710ade6e9e093e3c
ToppCellfacs-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 MAG P2RY12 SLC44A2 PIK3IP1 CLU

6.68e-06180113687fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCellfacs-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 MAG P2RY12 SLC44A2 PIK3IP1 CLU

6.68e-061801136c0c3144011856d005aebd5cdc79f89fee32083a8
ToppCellfacs-Bladder-nan-18m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG GPM6A LAPTM4A TMBIM6 LHCGR EGFL7

7.82e-0618511363e00879466e626aa8604efecfc4678d64f54dbfc
ToppCellfacs-Bladder-nan-18m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG GPM6A LAPTM4A TMBIM6 LHCGR EGFL7

7.82e-0618511363dc5812c961ff209f197ff4cbfb90009c0537550
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNH8 ADGRB3 GRIK4 LHCGR SCN7A GPR156

8.57e-061881136502045a39ffb1e92bd9499848368e8fa971edb88
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAG APOE SLC4A1 ADRB1 CLCNKB ATP6AP2

9.38e-061911136feec8617678b778475747ad406c80231e07fd6f7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GHRL P2RY12 RNASEK PIK3IP1 HHAT LYG1

1.02e-051941136b829a63b51b92507a53ffd0393bd9458b2b9440f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAG APOE SLC4A1 ADRB1 CLCNKB ATP6AP2

1.02e-0519411366165c00ec06a8393f23b0c62f679c143839b03b1
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

ATP6AP1 ACP5 ACTN1 PTAFR APOE TM4SF19

1.09e-05196113648f7516129570981846c667a07abe5a9abe62dcd
ToppCellParenchyma_COVID-19-Immune-TX-MoAM-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

A1BG ATP6AP1 ACP5 APOE ATP6AP2 TM4SF19

1.15e-051981136a7eed9eeb728a8796e2780090cc244856efd8c65
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma|TCGA-Bladder / Sample_Type by Project: Shred V9

COL3A1 PODNL1 ACP5 PSMD2 APOE PVR

1.15e-05198113665875fbd99393cdd62595c713ab90db06d28081f
ToppCellnormal_Lung-Endothelial_cells-Tip-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

LAPTM4A ADRB1 SLC12A2 IL1RL1 EGFL7 TAP1

1.18e-05199113672c96a5954dfcfbfee8f095984ce1f5249d9a679
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6A ACTN1 CLU APLNR IL1RL1 EGFL7

1.18e-05199113607bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VARS2 PEBP4 SLC5A4 PVR RHBDD3 EGFL7

1.18e-051991136079931e7196719f22a89cfad82f452ec67219ee5
ToppCell(7)_Mast_cell|World / shred on Cell_type and subtype

MAG LAPTM4A APOE CLU SCN7A IL1RL1

1.18e-051991136c0b5f1cb435da99a7e2ebac9ee7d7b1bd0e49b42
ToppCellParenchyma_Control_(B.)-Immune-TX-TRAM-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ACP5 ACTN1 PTAFR APOE SLC47A1 TM4SF19

1.22e-0520011367c56935446f10d202eafa1f9ee7cb0aae4c2607e
ToppCellSigmoid-(7)_Mast_cell-(70)_Mast|Sigmoid / shred on region, Cell_type, and subtype

LAPTM4A APOE CLU SCN7A IL1RL1 EGFL7

1.22e-0520011367224ee639d56509de854203653a85ab09e6f05fe
ToppCellSigmoid-Mast_cell|Sigmoid / Region, Cell class and subclass

LAPTM4A APOE CLU SCN7A IL1RL1 EGFL7

1.22e-052001136025125d8b9c6540d9cdeea7f0fe9c58aec2a16b0
ToppCellSigmoid-(7)_Mast_cell|Sigmoid / shred on region, Cell_type, and subtype

LAPTM4A APOE CLU SCN7A IL1RL1 EGFL7

1.22e-052001136bd8e0f027055bb34e99aa0e271ec3a0912f666bb
ToppCellSigmoid-Mast_cell-Mast|Sigmoid / Region, Cell class and subclass

LAPTM4A APOE CLU SCN7A IL1RL1 EGFL7

1.22e-052001136e7e49e192a86566ed96f1e54657dd2ebc9036d47
ToppCell(70)_Mast|World / shred on Cell_type and subtype

MAG LAPTM4A APOE CLU SCN7A IL1RL1

1.33e-052031136b7af2130b4965661b5a50717a7f82d8d498f8d08
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PODNL1 FMR1NB GNLY PTAFR A2ML1

3.44e-051451135b961b69befb15ff6f58635e0d4bda88ea732a346
ToppCellfacs-Liver-Non-hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOE SLC4A1 CLU MYLK4

3.80e-0514811355c853637f6058f78608ba0e76cda72a548d40710
ToppCellfacs-Liver-Non-hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOE SLC4A1 CLU MYLK4

3.80e-051481135763c598826445bf627989220cd7acd71c4f1ea36
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

PRPH2 GNLY RNASEK A2ML1 RHBDD3

3.80e-05148113581a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellfacs-Liver-Non-hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOE SLC4A1 CLU MYLK4

3.80e-051481135d3f224128593251b72429a1cd52e82f77df8e386
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

GPM6A PODNL1 PRPH2 SLC12A2 SCN7A

4.18e-0515111355906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

COL3A1 GRIN2C APOE CLCNKA CLU

4.31e-0515211353a1414ba6a4972698c3262a00b124428835c35cb
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

COL3A1 GRIN2C APOE CLCNKA CLU

4.31e-051521135ee7855d76a49d07a032677a4dc83aa6116d50518
ToppCellRV-16._Neuronal|RV / Chamber and Cluster_Paper

ADGRB3 PIK3IP1 SLC6A1 SCN7A PCDH10

4.45e-051531135bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTN4 GRIN2D APLNR SCN7A EGFL7

4.88e-0515611351928c86deb3bcd01db4ae76919a351066aadb39a
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADRB1 APLNR SCN7A TRPV3 EGFL7

5.03e-0515711352c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR UPK1A APOE LHCGR EGFL7

5.18e-051581135f41ee21e5888359d817be1e3a902c132cb68e350
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR UPK1A APOE LHCGR EGFL7

5.18e-051581135d689feb7f612aef170da76fcf14abf2dd589082b
ToppCellfacs-Brain_Myeloid-Cerebellum-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR UPK1A APOE LHCGR EGFL7

5.18e-051581135829ff3df46f173f2ff1c435e9bce35425e603b42
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A1 CLU APLNR SCN7A IL1RL1

5.34e-051591135ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG TMEM86B ADGRB2 RLN3 GPR153

5.34e-051591135d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A1 CLU APLNR SCN7A IL1RL1

5.34e-0515911357b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG TMEM86B ADGRB2 RLN3 GPR153

5.34e-051591135da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

MAG GPM6A UPK1A ADGRB3 EGFL7

5.50e-0516011350d4880f85565d8c540c94a8f8109147b3029279a
ToppCelldroplet-Liver-Hepatocytes-21m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A1BG PSEN2 APOA5 TMEM86B SLC47A1

6.19e-051641135c9866a289e120be4066e66275c3beb97ba67cca4
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL3A1 VLDLR SLC27A6 APOE SLC6A1

6.19e-051641135519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

A1BG MAG RPS6KA4 FMR1NB SFTPA2

6.55e-0516611359fa90d9d484563d44738bb2c6eb0775dffc4d549
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TMEM150B ACP5 APOE TM4SF19 PIGM

6.74e-051671135a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

GPM6A OTOP2 ADGRB3 CLCNKB SCN7A

7.13e-05169113541cb92b0558f0d5a3e511058efd9110258b88ee3
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

GPM6A OTOP2 ADGRB3 CLCNKB SCN7A

7.13e-05169113591f4b6a14708e701b2af22989004282041777491
ToppCellTCGA-Brain|World / Sample_Type by Project: Shred V9

GPM6A P2RY12 ADGRB3 GRIK4 NCAN

7.33e-051701135f78e360a6a44d599ec0d207cba4704e50aa314f8
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

TMEM150B ACP5 PTAFR APOE TM4SF19

7.33e-0517011353a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCelldroplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 TMEM150B P2RY12 RHBDD3 ZDHHC13

7.54e-0517111357ca404539344e14dcd90c746c9122f713a7db78b
ToppCelldroplet-Lung-nan-18m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 TMEM150B P2RY12 RHBDD3 ZDHHC13

7.54e-051711135ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 PODNL1 SLC5A4 IL1RL1 PCDH10

7.75e-0517211351ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 PODNL1 SLC5A4 IL1RL1 PCDH10

7.75e-051721135ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PODNL1 UPK1A ACP5 ADGRB2 TAP1

7.96e-051731135da0f1461643294f92e20b5e456a50211a2780a91
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR UPK1A APOE LHCGR EGFL7

7.96e-051731135ef862e1d626bbc33191b433f483addff7f75ba16
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK|GI_small-bowel / Manually curated celltypes from each tissue

LPCAT1 GNLY SFTPA2 LCN15 TM4SF19

8.18e-05174113509b216f07cffd3ea2149ea95ffb5cd7219b3a98c
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM202 TMEM150B APOE RHBDD3 ZDHHC13

8.18e-05174113533e5903adb746f693433bdca11a75c508bbf50c0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM202 TMEM150B APOE RHBDD3 ZDHHC13

8.18e-051741135ca0c2f42544092848541863c4a47b334e6828b8a
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB|TCGA-Thymus / Sample_Type by Project: Shred V9

GPM6A PODNL1 PRPH2 CLCNKB SCN7A

8.40e-05175113550f9b994bdd389158f92f891944ea81b2fb15eef
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 NPFFR1 CLCN1 GPR153 LCN15

8.87e-051771135aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 NPFFR1 CLCN1 GPR153 LCN15

8.87e-051771135d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 NPFFR1 CLCN1 GPR153 LCN15

8.87e-05177113570ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG GPM6A LPCAT1 SLC6A1 CLU

9.10e-0517811355cf12927f0756c4d8a289fe4308d736382e6212e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6AP1 APOE SLC4A1 CLCNKB ATP6AP2

9.10e-051781135f1cfc348d51362eb8c92c625f21f682afc0352b7
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMR1NB APLNR EGFL7 USH2A

9.27e-0593113493a8d3ad978e4cd450f7a69a4cbac1a59038e80d
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

ACP5 APOE LHCGR SLC47A1 TM4SF19

9.35e-051791135b4430f633711cecf793e8e76e766a66ff1eff473
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6AP1 TMEM87A SLC4A1 CLCNKB ATP6AP2

9.35e-05179113527ad6a609fe1f7532b142d0147bccf918704a6dd
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 OTOP2 CLCN1 LCN15 PVR

9.60e-0518011358ba9bba0c9fecf184a4332ba4585fb2439f68cd3
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

MAG VLDLR GHRL SLC12A2 HHAT

9.60e-051801135be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 OTOP2 CLCN1 PVR LPGAT1

9.85e-0518111351d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

MAG RPS6KA4 GHRL SLC44A2 SLC12A2

9.85e-0518111352caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 OTOP2 CLCN1 LCN15 PVR

9.85e-0518111351c04e53f46992a0aea9d3eee985681ec4e71f80d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 OTOP2 CLCN1 PVR LPGAT1

9.85e-0518111350069e8308de932df43660bbe926637c57b8bf7f6
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

MAG RPS6KA4 GHRL SLC44A2 SLC12A2

9.85e-051811135277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 OTOP2 CLCN1 LCN15 PVR

9.85e-05181113583adf61f44cebe9e75de175c5dc39237fbf9ed24
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL3A1 VLDLR SLC27A6 APOE MYLK4

1.01e-041821135ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 OTOP2 CLCN1 LCN15 PVR

1.01e-041821135e98ca9df33a1a81fc83ecf73d5141a14f2bc985c
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG KCNH8 ADGRB3 SLC6A1 OTOP1

1.01e-041821135d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 CLCNKB GPR153 SCN7A DMP1

1.01e-041821135f4b74c2756989812abe4e7055ec8918f69d56025
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG KCNH8 ADGRB3 SLC6A1 OTOP1

1.01e-041821135e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG KCNH8 ADGRB3 SLC6A1 OTOP1

1.01e-04182113582ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3-6_VIP_KCTD13|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 GRIN2D NPFFR1 SLC6A1 ST8SIA2

1.04e-041831135f06c06c75aab55fa8c803665afaa399446aec5af
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAG LAPTM4A CLU SCN7A IL1RL1

1.04e-0418311355ac38a2ce93c53f23a89faf287b81ea138560623
ToppCell3'_v3-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

LAPTM4A SLC27A6 CLU SCN7A IL1RL1

1.06e-04184113583675c7a083c52fb74dc8b9d35df0ef69715f707
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

APOE SLC4A1 ADRB1 CLCNKB ATP6AP2

1.06e-041841135282118f8221fa383ffb81dfb5798a0b7f065f911
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cells|lymph-node_spleen / Manually curated celltypes from each tissue

LAPTM4A SLC27A6 CLU SCN7A IL1RL1

1.06e-041841135ed266bd2d12f86e8786473e64fbcd58319cd4c2a
DrugAC1Q3ZOL

DRD5 GRIK4 GRIN2C GRIN2D NPFFR1 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB

6.12e-0825811211CID000002376
Drugibotenic acid

DRD5 GRIK4 GRIN2C GRIN2D CLCN1 CLCN2 CLCNKA CLCNKB

1.61e-071221128CID000001233
Drugpicrotoxin

DRD5 GRIK4 GRIN2C GRIN2D SLC6A1 CLCN1 CLCN2 CLCNKA CLCNKB

2.83e-071811129CID000031304
Druggamma-aminobutyric acid

A1BG DRD5 GRIK4 GRIN2C GRIN2D TMBIM6 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB TAP1

6.12e-0747411213CID000000119
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

P2RY12 SLC4A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB SLC13A5 TAP1

8.38e-072061129CID000040600
Drugtrans-4-aminocrotonic acid

A1BG SLC6A1 CLCN1 CLCN2 CLCNKA CLCNKB

9.68e-07671126CID000002766
DrugBN 52021

P2RY12 PTAFR CLCN1 CLCN2 CLCNKA CLCNKB

1.61e-06731126CID000065243
Drugtaurine

GRIN2C GRIN2D SLC4A1 SLC6A1 CLCN1 CLCN2 CLCNKA CLCNKB ST8SIA2

2.16e-062311129CID000001123
Druglubiprostone

GHRL CLCN1 CLCN2 CLCNKA CLCNKB

2.75e-06451125CID000157920
Drugnaphthol AS-BI phosphate

MAG ATP6AP1 ACP5 SLC4A1

3.79e-06221124CID000074715
Drugfurosemide

SLC4A1 SLC5A4 SLC6A1 CLCN1 CLCN2 SLC12A2 CLCNKA CLCNKB CLU

8.16e-062721129CID000003440
Drug2-chloropropionate

MAG GRIK4 GRIN2C GRIN2D

8.92e-06271124CID000011734
Drugbumetanide

SLC5A4 SLC6A1 CLCN1 SLC12A2 CLCNKA CLCNKB CLU SLC13A5

9.26e-062091128CID000002471
Drug1-phenylpyrazole

CLCN1 CLCN2 CLCNKA CLCNKB

1.04e-05281124CID000070769
Drugoriens

GRIK4 ACTN1 GRIN2C GRIN2D SLC6A1 ADRB1 NCAN

1.13e-051541127CID000161645
DrugLY293558

GHRL GRIK4 GRIN2C GRIN2D

1.38e-05301124CID000127894
DrugDepixol

DRD5 GRIK4 GRIN2C GRIN2D

2.03e-05331124CID000017011
Drugphen-oxy

CLCN1 SLC12A2 CLCNKA TAP1

2.30e-05341124CID000123143
Drug2-(4-chlorophenoxy)propionic acid

CLCN1 CLCNKA

2.40e-0521122ctd:C048213
Drugkainite

GRIK4 GRIN2C GRIN2D TAP1

2.58e-05351124CID000164810
DrugC6H12NO5P

DRD5 GRIK4 GRIN2C GRIN2D

2.89e-05361124CID000104962
Drug1,10-diaminodecane

GRIN2C GRIN2D DMP1

3.20e-05131123CID000001317
DrugAgmatine

GRIN2C GRIN2D SLC47A1

3.20e-05131123ctd:D000376
Drugbenzyloxyaspartate

GRIN2C GRIN2D SLC6A1 TAP1

3.23e-05371124CID004133412
Drug7-OH-DPAT

DRD5 GRIK4 GRIN2C GRIN2D

4.00e-05391124CID000001219
Drugmuscimol

DRD5 GRIK4 GRIN2C GRIN2D SLC6A1 SLC12A2

4.31e-051291126CID000004266
DrugClindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A

ADGRB2 PTAFR APOE PIK3IP1 CLCN1 PVR WDFY3

4.67e-0519211272219_UP
Drugaspartate

PSEN2 GRIK4 GRIN2C GRIN2D SLC6A1 LHCGR CLCN1 CLCN2 CLCNKA CLCNKB TAP1

5.04e-0551811211CID000000424
DrugACEA-1011

GRIK4 GRIN2C GRIN2D

5.05e-05151123CID000127872
DrugA 86929

DRD5 PTAFR ADRB1

5.05e-05151123ctd:C095427
Drugtetradotoxin

DRD5 P2RY12 GRIK4 GRIN2C GRIN2D SLC6A1 ADRB1 SCN7A ST8SIA2 TRPV3

5.10e-0542811210CID000020382
DrugAC1L63MU

PSEN2 GRIK4 GRIN2C GRIN2D PTAFR APOE LHCGR CLCNKA CLCNKB

5.54e-053471129CID000285703
DrugAC1L1B1W

GRIK4 GRIN2C GRIN2D SLC6A1 SLC12A2

5.97e-05841125CID000001248
Drugargiopine

GRIK4 GRIN2C GRIN2D

6.19e-05161123CID000122294
DrugAC1L1BXF

GRIK4 GRIN2C GRIN2D SLC6A1 TAP1

6.31e-05851125CID000001650
DrugIPSP

GRIK4 GRIN2C GRIN2D SLC6A1 CLCN2

7.06e-05871125CID000022083
Drugestradiol 3-benzoate

COL3A1 GRIN2C SLC6A1 LHCGR CLU

7.87e-05891125ctd:C074283
Drugpilocarpine-

DRD5 GRIK4 GRIN2C GRIN2D SLC6A1 ADRB1

8.91e-051471126CID000004819
Drugserotonin

DRD5 AOC1 RPS6KA4 GHRL P2RY12 SLC6A1 ADRB1 CLCN1 CLCN2 CLCNKA CLCNKB

9.17e-0555411211CID000005202
Drugarcaine

AOC1 GRIN2C GRIN2D

1.06e-04191123CID000002227
DrugAC1L1FA8

GRIK4 GRIN2C GRIN2D ST8SIA2

1.07e-04501124CID000003150
Drugazelnidipine

COL3A1 ACTN4 APOE ADRB1

1.16e-04511124CID000065948
Drugfullerene C60

DRD5 RPS6KA4 APOA5 SLC44A2 PRPH2 ACTN4 GRIN2D SLC4A1 GJD4 NEMP2 PIK3IP1 ADRB1 ATP6AP2 GPR153 OTOP1 GPR156 SLC47A1 PCDH10 VARS1

1.23e-04149811219ctd:C069837
DrugIDRA 21

GRIK4 GRIN2C GRIN2D

1.24e-04201123CID000003688
Drugantineutrophil cytoplasmic antibody

CLCN1 CLCN2 SLC12A2 CLCNKA

1.25e-04521124CID000002201
DrugAC1L1EKQ

GRIK4 GRIN2C GRIN2D ADRB1

1.25e-04521124CID000002834
DrugQuinoxaline

ATP6AP1 GRIK4 GRIN2C GRIN2D

1.25e-04521124CID000007045
DrugATFP

COL3A1 PVR

1.43e-0441122CID000193783
Drugadenosine 3',5'-cyclic phosphate

DRD5 KCNH8 RPS6KA4 P2RY12 LIPF APOE LHCGR ADRB1 CLCN1 CLCN2 CLCNKA CLCNKB CLU ADIPOR2

1.47e-0490711214CID000000274
Drugindoxyl

MAG ATP6AP1 ACP5 GBA2

1.56e-04551124CID000050591
DrugAC1L1D9R

CLCN1 CLCN2 CLCNKA CLCNKB CLU

1.57e-041031125CID000002254
DrugNS 102

GRIK4 GRIN2C GRIN2D

1.67e-04221123CID005282252
DrugCX516

GRIK4 GRIN2C GRIN2D

1.67e-04221123CID000148184
DiseaseSchizophrenia

A1BG COL3A1 MAG GPM6A VLDLR PSEN2 GRIK4 GRIN2C GRIN2D APOE SLC6A1 SLC12A2 CLU GPR153 HHAT NCAN ST8SIA2 TAP1

4.70e-0988311018C0036341
Diseasefocal segmental glomerulosclerosis 1 (implicated_via_orthology)

ACTN4 ACTN1 ACTN3

5.01e-0751103DOID:0111128 (implicated_via_orthology)
DiseaseBartter disease type 4B

CLCNKA CLCNKB

1.38e-0521102cv:C4310805
DiseaseALZHEIMER DISEASE 4

PSEN2 APOE

1.38e-0521102606889
DiseaseBartter disease type 3 (implicated_via_orthology)

CLCNKA CLCNKB

1.38e-0521102DOID:0110144 (implicated_via_orthology)
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

1.38e-0521102613090
DiseaseALZHEIMER DISEASE 4

PSEN2 APOE

1.38e-0521102C1847200
DiseaseBARTTER SYNDROME, TYPE 4B

CLCNKA CLCNKB

1.38e-0521102C2751312
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

1.38e-0521102C4310805
Diseasecombined oxidative phosphorylation deficiency 20 (implicated_via_orthology)

VARS2 VARS1

1.38e-0521102DOID:0111478 (implicated_via_orthology)
DiseaseBartter disease type 4b (is_implicated_in)

CLCNKA CLCNKB

1.38e-0521102DOID:0110146 (is_implicated_in)
DiseaseBartter disease (implicated_via_orthology)

CLCNKA CLCNKB

1.38e-0521102DOID:445 (implicated_via_orthology)
DiseaseAlzheimer disease 4

PSEN2 APOE

1.38e-0521102cv:C1847200
DiseaseHyperlipoproteinemia Type III

APOA5 APOE

1.38e-0521102C0020479
Diseasepipecolate measurement

LAPTM4A SLC6A1 MYLK4

1.40e-05131103EFO_0021006
Diseasemiddle cerebral artery infarction (implicated_via_orthology)

MAG GHRL APOE SLC12A2

2.42e-05451104DOID:3525 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

CLCN1 CLCN2 CLCNKA CLCNKB

3.13e-05481104DOID:423 (implicated_via_orthology)
DiseaseGeneralized seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0234533
DiseaseClonic Seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0234535
DiseaseConvulsive Seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0751494
DiseaseSeizures, Sensory

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0751496
DiseaseNon-epileptic convulsion

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0751056
DiseaseAtonic Absence Seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0751123
DiseaseComplex partial seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0149958
DiseaseSingle Seizure

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0751110
DiseaseNonepileptic Seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C3495874
DiseaseVisual seizure

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0270824
DiseaseEpileptic drop attack

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0270846
DiseaseVertiginous seizure

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0422855
DiseaseGustatory seizure

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0422854
DiseaseSeizures, Somatosensory

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0422850
DiseaseOlfactory seizure

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0422853
DiseaseSeizures, Auditory

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0422852
DiseaseGeneralized Absence Seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C4505436
DiseaseJacksonian Seizure

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C0022333
DiseaseEpileptic Seizures

GHRL APOE SLC6A1 CLU PIGM

3.91e-051011105C4317109
DiseaseAbsence Seizures

GHRL APOE SLC6A1 CLU PIGM

4.10e-051021105C4316903
DiseaseConvulsions

GHRL APOE SLC6A1 CLU PIGM

4.10e-051021105C4048158
DiseaseTonic Seizures

GHRL APOE SLC6A1 CLU PIGM

4.10e-051021105C0270844
DiseaseRare dyslipidemia

APOA5 APOE

4.12e-0531102Orphanet_101953
DiseaseSeizures, Focal

GHRL APOE SLC6A1 CLU PIGM

4.51e-051041105C0751495
DiseaseMyoclonic Seizures

GHRL APOE SLC6A1 CLU PIGM

4.51e-051041105C4317123
DiseaseTonic - clonic seizures

GHRL APOE SLC6A1 CLU PIGM

4.51e-051041105C0494475
Diseasedepressive disorder (implicated_via_orthology)

GPM6A DRD5 RNF103

7.37e-05221103DOID:1596 (implicated_via_orthology)
DiseaseHypertensive disease

COL3A1 AOC1 APOE ADRB1 SLC12A2 CLCNKA

8.10e-051901106C0020538
DiseaseX-24020 measurement

AOC1 TUBGCP6

1.37e-0451102EFO_0022128
Diseaselinoleoyl-linoleoyl-glycerol (18:2/18:2) [1] measurement

APOA5 APOE

1.37e-0451102EFO_0800510
DiseaseBartter syndrome

CLCNKA CLCNKB

2.05e-0461102cv:C0004775
Diseaseatherosclerosis (implicated_via_orthology)

APOE CLU

2.86e-0471102DOID:1936 (implicated_via_orthology)
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

VARS2 VARS1

2.86e-0471102DOID:0060475 (implicated_via_orthology)
DiseaseEarly-onset autosomal dominant Alzheimer disease

PSEN2 APOE

2.86e-0471102cv:CN043596
Diseaseexfoliation syndrome (is_implicated_in)

APOE CLU

2.86e-0471102DOID:13641 (is_implicated_in)
DiseaseCardiovascular Diseases

APOE ADRB1 SLC12A2

3.29e-04361103C0007222
Diseaseepilepsy (implicated_via_orthology)

GRIN2C GRIN2D SLC12A2 SCN7A SLC13A5

3.71e-041631105DOID:1826 (implicated_via_orthology)
Diseasecerebrovascular disease (is_implicated_in)

P2RY12 APOE

3.80e-0481102DOID:6713 (is_implicated_in)
Diseaselow tension glaucoma (is_implicated_in)

APOE ADRB1

3.80e-0481102DOID:13544 (is_implicated_in)
DiseaseAlzheimer disease

PSEN2 APOE

3.80e-0481102cv:C0002395
Diseasemitochondrial encephalomyopathy (implicated_via_orthology)

VARS2 VARS1

3.80e-0481102DOID:890 (implicated_via_orthology)
DiseaseHyperlipoproteinemia

APOA5 APOE

3.80e-0481102cv:C0020476
Diseasediacylglycerol 36:4 measurement

APOA5 APOE

4.87e-0491102EFO_0020063
DiseaseEndomyocardial Fibrosis

COL3A1 ADRB1

4.87e-0491102C0553980
Diseasecholesteryl esters to total lipids in small LDL percentage

APOA5 APOE NCAN

5.21e-04421103EFO_0022255
Diseaseplatelet component distribution width

COL3A1 APOA5 SLC44A2 PSMD2 ACTN1 APOE ADRB1 PVR EGFL7 HERC1

5.33e-0475511010EFO_0007984
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

CLCNKA CLCNKB

6.08e-04101102DOID:12387 (implicated_via_orthology)
Diseaselinoleoyl-arachidonoyl-glycerol (18:2/20:4) [1] measurement

APOE NCAN

6.08e-04101102EFO_0800499
Diseaseglomerulosclerosis (biomarker_via_orthology)

COL3A1 APOE

6.08e-04101102DOID:0050851 (biomarker_via_orthology)
DiseaseAmyloidosis

APOE ZDHHC13

6.08e-04101102C0002726
Diseaseopen-angle glaucoma (is_implicated_in)

APOE TAP1

8.87e-04121102DOID:1067 (is_implicated_in)
DiseaseN-acetylputrescine measurement

AOC1 TUBGCP6

8.87e-04121102EFO_0800127
Diseaselinoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement

APOE NCAN

8.87e-04121102EFO_0800500
Diseasebeta-endorphin measurement

APOA5 APOE

8.87e-04121102EFO_0008034
DiseaseObesity

VLDLR GHRL ACP5 APOE ADRB1

1.05e-032051105C0028754
DiseaseN-acetyl-isoputreanine measurement

AOC1 SLC47A1

1.05e-03131102EFO_0800107
Diseasesterol measurement

APOA5 APOE

1.05e-03131102EFO_0010231
Diseasebacterial pneumonia (biomarker_via_orthology)

SFTPA2 IL1RL1

1.22e-03141102DOID:874 (biomarker_via_orthology)
DiseaseSeizures

GHRL APOE SLC6A1 CLU PIGM

1.37e-032181105C0036572
Diseaseatherosclerosis (is_implicated_in)

APOE CLU

1.60e-03161102DOID:1936 (is_implicated_in)
Diseasediacylglycerol 36:3 measurement

APOA5 APOE

2.03e-03181102EFO_0020062
DiseaseX-11470 measurement

VARS2 VARS1

2.26e-03191102EFO_0021241
Diseaseinsomnia, total blood protein measurement

SLC27A6 ADRB1 SLC13A5 PCDH10

2.32e-031481104EFO_0004536, EFO_0004698
Diseasemetabolite measurement, diet measurement

APOA5 APOE SLC13A5

2.40e-03711103EFO_0004725, EFO_0008111
Diseasefamily history of Alzheimer’s disease

APOE CLU PVR

2.40e-03711103EFO_0009268
Diseasebreast cancer (is_implicated_in)

PSEN2 APOE LHCGR CLU

2.44e-031501104DOID:1612 (is_implicated_in)
DiseaseInfiltrating duct carcinoma of female breast

RPS6KA4 MYLK4

2.76e-03211102C3165106
DiseaseDepression, Bipolar

DRD5 GRIK4 NCAN

3.24e-03791103C0005587
Diseasesquamous cell lung carcinoma

VARS2 NPFFR1 EGFL7 VARS1

3.44e-031651104EFO_0000708
DiseaseHDL cholesterol change measurement

APOA5 APOE

3.60e-03241102EFO_0007805

Protein segments in the cluster

PeptideGeneStartEntry
LPLLALTWMSAVLAM

ADGRB2

1161

O60241
QWTAGMGLLMALIVL

ADRB1

56

P08588
MRGSQEVLLMWLLVL

EGFL7

1

Q9UHF1
KMTLGMIWTIILRFA

ACTN1

121

P12814
MKVLWAALLVTFLAG

APOE

1

P02649
IWMMFASALPALLVF

SLC4A1

661

P02730
LPLLALTWMSAVLAM

ADGRB3

1106

O60242
MWAQLLLGMLALSPA

A2ML1

1

A8K2U0
MTLGMIWTIILRFAI

ACTN4

141

O43707
MASMAAVLTWALALL

APOA5

1

Q6Q788
MTWLVLLGTLLCMLR

AMIGO3

1

Q86WK7
MPALGWAVAAILMLQ

AOC1

1

P19801
ATIGQIGWLMLMASL

ADIPOR2

306

Q86V24
IGWLMLMASLYITGA

ADIPOR2

311

Q86V24
MARYMLLLLLAVWVL

RLN3

1

Q8WXF3
MALVMVGLAWTLSIL

DRD5

156

P21918
MANLMLQGLLARWLA

INO80

901

Q9ULG1
LVTMGGWLTLMVAYL

LRRC3C

226

A6NJW4
MSMLVVFLLLWGVTW

A1BG

1

P04217
AVLWVLAALLAMPVM

APLNR

151

P35414
MLVMVALFFTLSWLP

NPFFR1

271

Q9GZQ6
VRLLVAAAMMLLAWP

LPCAT1

56

Q8NF37
AAAMMLLAWPLALVA

LPCAT1

61

Q8NF37
IMLGGWLFSSLIAML

LHCGR

486

P22888
LGWLLVKALMRFAFM

LPGAT1

11

Q92604
MIFLTALPLFWIMIS

MAG

1

P20916
LFSEMWDIFLVRLLM

MFSD9

281

Q8NBP5
IMLTYLFMLAWLGVT

GPM6A

131

P51674
ILGTWYMVVNLLMAI

LAPTM4A

31

Q15012
LSLLFALLRQSWMMP

HERC1

166

Q15751
VGKLWFVLTMLLRML

GJD4

21

Q96KN9
MWLLLTMASLISVLG

LIPF

1

P07098
MGWTMRLVTAALLLG

PEBP4

1

Q96S96
LMWMLRLLSLVLVYA

NEMP2

271

A6NFY4
VMGIWMVSFILSALP

GPR153

131

Q6NV75
MATWALLLLAAMLLG

GNLY

1

P22749
MWSVGVIAYMLLSGL

MYLK4

286

Q86YV6
GVFSFLLQLKLMMWA

TUBGCP6

1626

Q96RT7
DLWSLGVILYMMLSG

RPS6KA4

591

O75676
MMSFLLGAILTLLWA

LCN15

1

Q6UWW0
MLLAWVQAFLVSNML

PIK3IP1

1

Q96FE7
MIVLLLFALLWMVEG

PCDH10

1

Q9P2E7
VVIWAFMFLLSLPNM

P2RY12

146

Q9H244
MKISILLMFLWGLSC

DMP1

1

Q13316
LTAMMLLATLWILFY

OTOP2

66

Q7RTS6
LVWLLLGHMVVSQMA

HHAT

71

Q5VTY9
LMLAWVLVGSDMALV

OR56B4

206

Q8NH76
MAESGLAMWPSLLLL

PODNL1

1

Q6PEZ8
LTALMLLQLLWMLWY

OTOP1

96

Q7RTM1
VFNMVLWIMIALALA

ATP6AP2

306

O75787
MGFWILAILTILMYS

IL1RL1

1

Q01638
LWLAAVAVMVQMAAL

GBA2

691

Q9HCG7
LLLGMLWLDLAMAGS

GHRL

11

Q9UBU3
ALSALLMTSGLAMWF

MT-CO3

21

P00414
ALGSLILMIWLMATP

TMBIM6

61

P55061
MSALWLLLGLLALMD

LYG1

1

Q8N1E2
ALLMADVILLMTWVL

GPR156

171

Q8NFN8
ILLRFLAGIMVWVMI

SLC44A2

251

Q8IWA5
MMSFVQKGSWLLLAL

COL3A1

1

P02461
LIVAIFMAMLEFLWT

GRIK4

816

Q16099
SKPFGMLMLSIWILL

FMR1NB

66

Q8N0W7
LFVLSLVLVNLMAWM

RNF103

326

O00237
LVLVNLMAWMDLFIT

RNF103

331

O00237
MLVMLLFAWLWLQFV

SLC13A5

261

Q86YT5
LVSLIGAMIVYWVLM

SLC38A9

206

Q8NBW4
FMKLIIFSWALGFML

OR10A6

141

Q8NH74
ILWMYLMILLGNGVL

OR13C8

31

Q8NGS7
MQLLGLLSILWMLKS

MUC3B

1

Q9H195
MARAMAAAWPLLLVA

PVR

1

P15151
LFFWVARMVMLGLKL

VARS1

826

P26640
LLLFWVGRMVMLGTQ

VARS2

621

Q5ST30
LWFIVLMAMLGLILL

USH2A

5041

O75445
FMLAFGSLIASMWIL

TMEM50A

101

O95807
WAILFFSMLLMLGID

SLC6A1

381

P30531
MLLPALLFGMAWALA

SSPOP

1

A2VEC9
VSRVMVWMLLGALLL

TAS2R3

126

Q9NYW6
WVVAMLLFALFGLLA

TMEM150B

186

A6NC51
GMLSAAASLGMILLW

PSMD2

406

Q13200
MADMLFLITLPLWIV

PTAFR

61

P25105
VWALGLLMLQMLLFV

NCAN

6

O14594
MQLQFRSWMLAALTL

ST8SIA2

1

Q92186
FLVVMAVGLWAMLKT

SLC5A4

36

Q9NY91
LLGIMLWGSVSLTMV

TAP1

316

Q03518
MWLCPLALTLILMAA

SFTPA2

1

Q8IWL1
LLDFLGMIFLTMIWA

OMA1

346

Q96E52
WASFLRLAIPSMLML

SLC47A1

256

Q96FL8
MTLGMIWTIILRFAI

ACTN3

136

Q08043
TLAFFLVMKFWMLIL

CLCNKA

401

P51800
TLAFFLVMKFWMLIL

CLCNKB

401

P51801
LVLLGLLMALVSWSM

CLCN1

121

P35523
LLGLLMALVSWVMDY

CLCN2

96

P51788
VIFILMKFWMSALAT

CLCN2

436

P51788
MMKTLLLFVGLLLTW

CLU

1

P10909
LASSVLMLLMSTLWL

RHBDD3

16

Q9Y3P4
IAFITMMIISLAWLI

RNF149

206

Q8NC42
FLLLGMLRSMLTSPW

WDFY3

1841

Q8IZQ1
ELFLLLMLSVITMWA

ZDHHC13

291

Q8IUH4
LMLSVITMWAIGYIL

ZDHHC13

296

Q8IUH4
LMNSMGVVTLLIWLF

PRPH2

261

P23942
MLNIWGVMLFIRLSW

SLC12A2

296

P55011
MDMWTALLILQALLL

ACP5

1

P13686
KFIHGWLIMSSLMLL

PSEN2

166

P49810
VAAYGLILMAMLWRG

TMEM86B

151

Q8N661
MAMLLGASVLILWLQ

TRAV29DV5

1

P04437
IWMGLLTSLFMLFIF

ATP6AP1

426

Q15904
FGFAILMWTLPVMLI

UPK1A

236

O00322
WLQLLGRMFVLIWAM

TRPV3

481

Q8NET8
LMIWLIFSIMGVDLF

SCN7A

1066

Q01118
MMAAGAALALALWLL

TMED1

1

Q13445
MLLSWLTVLGAGMVV

SLC27A6

1

Q9Y2P4
VLSAWGVIMLIMLGI

RNASEK

56

Q6P5S7
FSLLMLIAMSPLNWV

TMEM202

66

A6NGA9
RAVVLLMLWFIGQAM

PIGM

356

Q9H3S5
LMVLTAAILISLMGW

TM4SF19

66

Q96DZ7
RLLFSMILFVIMVLW

TMEM87A

446

Q8NBN3
MAGIRALFMYLWLQL

TRAV13-2

1

A0A0B4J235
LLLVMAAVGGYLMWR

VLDLR

806

P98155
LTLLMSMFALLAHWM

KCNH8

356

Q96L42
MLLVAMGLALLVFAW

GRIN2C

821

Q14957
MLLVAMGLSLLVFAW

GRIN2D

851

O15399