Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	EPHB3 OR10D3 OR12D3 OR2K2 ANTXRL ITGA11 OR2A7 OR13D1 EFEMP1 TRHR PTPRK OR10G2 LPAR6 OR2A4 OR13F1 PECAM1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 GRIN2C ADGRV1 OR2Z1 OR51B4 GPR45	9.18e-14	1353	79	28	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.05e-11	431	79	16	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 TRHR OR10G2 LPAR6 OR2A4 OR13F1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 ADGRV1 OR2Z1 OR51B4 GPR45	1.91e-11	884	79	21	GO:0004930
GeneOntologyMolecularFunction	odorant binding	OR12D3 OR2A7 OR2A4 OR5C1 OR6K3 OR8K3 OR8U3	7.07e-07	127	79	7	GO:0005549
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	8.23e-12	432	80	16	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	2.47e-11	465	80	16	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	4.62e-11	485	80	16	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 ADGRV1 OR2Z1 OR51B4	7.06e-11	582	80	17	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.45e-10	524	80	16	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	2.71e-10	547	80	16	GO:0007606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR10D3 OR12D3 OR2K2 OR2A7 PDE4B OR13D1 TRHR OR10G2 LPAR6 OR2A4 OR13F1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 ADGRV1 OR2Z1 PDE10A OR51B4 GPR45	1.68e-09	1395	80	23	GO:0007186
GeneOntologyBiologicalProcess	detection of stimulus	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 ADGRV1 OR2Z1 OR51B4	1.91e-09	722	80	17	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 EFEMP1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 ADGRV1 OR2Z1 OR51B4	1.10e-07	1072	80	18	GO:0007600
GeneOntologyBiologicalProcess	negative regulation of neuron projection development	SEMA3F EFEMP1 AMIGO3 PTPRS FAT3 MDM2	5.04e-05	169	80	6	GO:0010977
GeneOntologyBiologicalProcess	negative regulation of cell projection organization	SEMA3F EFEMP1 AMIGO3 PTPRS FAT3 MDM2	2.92e-04	233	80	6	GO:0031345
GeneOntologyBiologicalProcess	negative regulation of interferon-alpha production	PTPRS NLRC3	3.08e-04	7	80	2	GO:0032687
Domain	GPCR_Rhodpsn_7TM	OR12D3 OR2K2 OR2A7 OR13D1 TRHR OR10G2 LPAR6 OR2A4 OR13F1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4 GPR45	4.03e-11	670	80	19	IPR017452
Domain	7tm_1	OR12D3 OR2K2 OR2A7 OR13D1 TRHR OR10G2 LPAR6 OR2A4 OR13F1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4 GPR45	4.81e-11	677	80	19	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR12D3 OR2K2 OR2A7 OR13D1 TRHR OR10G2 LPAR6 OR2A4 OR13F1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4 GPR45	5.88e-11	685	80	19	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR12D3 OR2K2 OR2A7 OR13D1 TRHR OR10G2 LPAR6 OR2A4 OR13F1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4 GPR45	6.82e-11	691	80	19	PS50262
Domain	GPCR_Rhodpsn	OR12D3 OR2K2 OR2A7 OR13D1 TRHR OR10G2 LPAR6 OR2A4 OR13F1 OR4D1 OR5C1 NMUR1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4 GPR45	6.99e-11	692	80	19	IPR000276
Domain	Olfact_rcpt	OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.03e-10	393	80	15	IPR000725
Domain	-	PAPOLA PAPOLB	5.42e-05	3	80	2	3.30.70.590
Domain	PAP_central	PAPOLA PAPOLB	5.42e-05	3	80	2	PF04928
Domain	PAP_RNA-bind	PAPOLA PAPOLB	5.42e-05	3	80	2	PF04926
Domain	PolA_pol_cen_dom	PAPOLA PAPOLB	5.42e-05	3	80	2	IPR007012
Domain	PolA_pol_RNA-bd_dom	PAPOLA PAPOLB	5.42e-05	3	80	2	IPR007010
Domain	PolyA_polymerase	PAPOLA PAPOLB	5.42e-05	3	80	2	IPR014492
Domain	NuclTrfase_I_C	PAPOLA PAPOLB	5.42e-05	3	80	2	IPR011068
Domain	PTPc	PTPN4 PTPRK PTPRS	4.88e-04	36	80	3	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPN4 PTPRK PTPRS	6.19e-04	39	80	3	PS50055
Domain	Galactose-bd-like	EPHB3 CPXM2 PTPRK MKLN1	7.10e-04	94	80	4	IPR008979
Domain	PTPase_domain	PTPN4 PTPRK PTPRS	7.17e-04	41	80	3	IPR000242
Domain	Y_phosphatase	PTPN4 PTPRK PTPRS	7.17e-04	41	80	3	PF00102
Domain	NTP_transf_2	PAPOLA PAPOLB	9.72e-04	11	80	2	PF01909
Domain	Polymerase_NTP_transf_dom	PAPOLA PAPOLB	9.72e-04	11	80	2	IPR002934
Domain	PTPc_motif	PTPN4 PTPRK PTPRS	2.07e-03	59	80	3	SM00404
Domain	Tyr_Pase_cat	PTPN4 PTPRK PTPRS	2.07e-03	59	80	3	IPR003595
Domain	PDEase	PDE4B PDE10A	2.96e-03	19	80	2	IPR023088
Domain	PDEase_I	PDE4B PDE10A	3.61e-03	21	80	2	PF00233
Domain	PDEASE_I	PDE4B PDE10A	3.61e-03	21	80	2	PS00126
Domain	PDEase_CS	PDE4B PDE10A	3.61e-03	21	80	2	IPR023174
Domain	-	EPHB3 CPXM2 MKLN1	3.79e-03	73	80	3	2.60.120.260
Domain	Tyr_Pase_AS	PTPN4 PTPRK PTPRS	3.79e-03	73	80	3	IPR016130
Domain	-	PDE4B PDE10A	3.96e-03	22	80	2	1.10.1300.10
Domain	NACHT	NLRC5 NLRC3	4.32e-03	23	80	2	PS50837
Domain	NACHT_NTPase	NLRC5 NLRC3	4.32e-03	23	80	2	IPR007111
Domain	PDEase_catalytic_dom	PDE4B PDE10A	4.32e-03	23	80	2	IPR002073
Domain	HDc	PDE4B PDE10A	4.70e-03	24	80	2	SM00471
Domain	HD/PDEase_dom	PDE4B PDE10A	4.70e-03	24	80	2	IPR003607
Domain	fn3	EPHB3 PTPRK PTPRS HCFC2	5.17e-03	162	80	4	PF00041
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	3.44e-11	417	64	16	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.46e-10	389	64	15	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.58e-08	636	64	16	M41834
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.14e-16	340	82	16	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.14e-16	340	82	16	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.31e-16	343	82	16	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1 OR51B4	1.50e-16	346	82	16	14611657
Pubmed	The human olfactory receptor gene family.	OR10D3 OR12D3 OR2K2 OR2A7 OR13D1 OR10G2 OR2A4 OR13F1 OR4D1 OR5C1 OR6Y1 OR6K3 OR8K3 OR8U3 OR2Z1	2.39e-12	541	82	15	14983052
Pubmed	Regulation of spermatogenesis by testis-specific, cytoplasmic poly(A) polymerase TPAP.	PAPOLA PAPOLB	5.49e-06	2	82	2	12471261
Pubmed	Transcription factor TAFII250 promotes Mdm2-dependent turnover of p53.	TAF1 MDM2	1.64e-05	3	82	2	17237821
Pubmed	Transcription factor TAFII250 phosphorylates the acidic domain of Mdm2 through recruitment of protein kinase CK2.	TAF1 MDM2	1.64e-05	3	82	2	18548200
Pubmed	Complex alternative RNA processing generates an unexpected diversity of poly(A) polymerase isoforms.	PAPOLA PAPOLB	1.64e-05	3	82	2	8628305
Pubmed	Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.	OR2A7 OR2A4	1.64e-05	3	82	2	27315375
Pubmed	TAF1 differentially enhances androgen receptor transcriptional activity via its N-terminal kinase and ubiquitin-activating and -conjugating domains.	TAF1 MDM2	1.64e-05	3	82	2	20181722
Pubmed	The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter.	TAF1 MDM2	1.64e-05	3	82	2	9388200
Pubmed	A zonal organization of odorant receptor gene expression in the olfactory epithelium.	OR2A7 OR2A4	3.28e-05	4	82	2	7683976
Pubmed	Tat-dependent occlusion of the HIV poly(A) site.	PAPOLA PAPOLB	3.28e-05	4	82	2	8491200
Pubmed	Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4.	LPAR6 PECAM1	3.28e-05	4	82	2	31335323
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CSDE1 TBC1D9B PTPRK STC2 USO1 INF2 POLR2B CSTF3 ERLEC1 IPO11	7.44e-05	942	82	10	31073040
Pubmed	CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2.	RNF34 MDM2	8.19e-05	6	82	2	18382127
Pubmed	Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.	PECAM1 MDM2	8.19e-05	6	82	2	20855528
Pubmed	EphB2 and EphB3 forward signalling are required for palate development.	EPHB3 PECAM1	8.19e-05	6	82	2	19032981
Pubmed	Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.	PDE4B PDE10A	8.19e-05	6	82	2	18923023
Pubmed	Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis.	EPHB3 PECAM1	1.14e-04	7	82	2	9990854
Pubmed	Saturation mutagenesis defines novel mouse models of severe spine deformity.	OR2A7 OR2A4	1.52e-04	8	82	2	34142127
Pubmed	The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation.	PAPOLA CSTF3	1.52e-04	8	82	2	7590244
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR4D1 OR6Y1 OR6K3	1.78e-04	46	82	3	32126975
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CSDE1 PTPN4 INF2 RBBP4 PTPRS SLC16A14 MKLN1 NLRC5 CSTF3 ADGRV1 PDE10A GPT2	1.88e-04	1489	82	12	28611215
Pubmed	Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.	PAPOLA CSTF3	1.96e-04	9	82	2	14749727
Pubmed	Refuting the hypothesis that semaphorin-3f/neuropilin-2 exclude blood vessels from the cap mesenchyme in the developing kidney.	SEMA3F PECAM1	1.96e-04	9	82	2	28929539
Pubmed	Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly.	EPHB3 PECAM1	2.44e-04	10	82	2	16413489
Pubmed	TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry.	POLR2B PECAM1	2.44e-04	10	82	2	38490996
Pubmed	Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.	SEMA3F PECAM1	2.44e-04	10	82	2	15550623
Pubmed	Class 3 semaphorins negatively regulate dermal lymphatic network formation.	SEMA3F PECAM1	2.98e-04	11	82	2	26319580
Pubmed	Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature.	SEMA3F PECAM1	2.98e-04	11	82	2	26385750
Pubmed	Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.	PECAM1 MDM2	2.98e-04	11	82	2	22734001
Pubmed	A balance of noncanonical Semaphorin signaling from the cerebrospinal fluid regulates apical cell dynamics during corticogenesis.	SEMA3F PECAM1	3.57e-04	12	82	2	36399562
Pubmed	Evolution of odorant receptors expressed in mammalian testes.	OR2A7 OR2A4	4.21e-04	13	82	2	11014824
Pubmed	Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.	OR2A7 OR2A4	4.91e-04	14	82	2	7528109
Pubmed	Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.	NLRC5 NLRC3	4.91e-04	14	82	2	26320999
Pubmed	Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo.	PECAM1 MDM2	4.91e-04	14	82	2	31749402
Pubmed	Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation.	EFEMP1 PECAM1	4.91e-04	14	82	2	22665518
Pubmed	Phosphorylation of the RAP74 subunit of TFIIF correlates with Tat-activated transcription of the HIV-1 long terminal repeat.	POLR2B TAF1	5.65e-04	15	82	2	10704353
Pubmed	Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.	POLR2B TAF1	5.65e-04	15	82	2	14992727
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	AMIGO3 PTPRK PTPRS PECAM1	5.98e-04	162	82	4	25826454
Pubmed	Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.	PTPN4 PTPRK	6.45e-04	16	82	2	8875997
Pubmed	Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina.	PTPRK PTPRS	6.45e-04	16	82	2	18308476
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR6Y1 OR8K3 OR2Z1	7.26e-04	74	82	3	15081110
Pubmed	Protein tyrosine phosphatases expression during development of mouse superior colliculus.	PTPRK PTPRS	7.30e-04	17	82	2	19727691
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	RBBP4 TAF1 SP140	7.55e-04	75	82	3	25593309
Pubmed	Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development.	EPHB3 PECAM1	8.20e-04	18	82	2	16514057
Pubmed	Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity.	EPHB3 PECAM1	8.20e-04	18	82	2	18651661
Pubmed	Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.	TAF1 MDM2	8.20e-04	18	82	2	15053879
Pubmed	Proteomic analysis identifies novel binding partners of BAP1.	RBBP4 POLR2B HCFC2	9.11e-04	80	82	3	34591877
Pubmed	PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development.	SEMA3F PECAM1	9.15e-04	19	82	2	15239958
Pubmed	Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice.	EPHB3 PECAM1	9.15e-04	19	82	2	15184386
Pubmed	ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.	RBBP4 TAF1	1.12e-03	21	82	2	12453419
Pubmed	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.	SEMA3F PECAM1	1.12e-03	21	82	2	36240771
Pubmed	Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells.	EPHB3 MDM2	1.23e-03	22	82	2	15162501
Pubmed	Distinct fibroblast lineages determine dermal architecture in skin development and repair.	EPHB3 PECAM1	1.23e-03	22	82	2	24336287
Pubmed	The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.	USO1 MDM2	1.47e-03	24	82	2	24798327
Pubmed	Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia.	SEMA3F PECAM1	1.47e-03	24	82	2	23063659
Pubmed	The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.	POLR2B TAF1	1.59e-03	25	82	2	19240132
Pubmed	Overview of PDEs and their regulation.	PDE4B PDE10A	1.59e-03	25	82	2	17307970
Pubmed	Motor innervation directs the correct development of the mouse sympathetic nervous system.	SEMA3F PECAM1	1.59e-03	25	82	2	39152112
Pubmed	Expression of members of the putative olfactory receptor gene family in mammalian germ cells.	OR10D3 OR2K2	1.59e-03	25	82	2	1370859
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	ENPP6 RBBP4 POLR2B SHMT2 TAF1 HCFC2 MDM2	1.70e-03	730	82	7	34857952
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	POLR2B ASPM NHS MDM2 FIGNL1	1.70e-03	363	82	5	14691545
Pubmed	Extra-embryonic vasculature development is regulated by the transcription factor HAND1.	EPHB3 PECAM1	1.99e-03	28	82	2	15073150
Pubmed	Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.	CSDE1 PAPOLA USO1 RBBP4 SHMT2	2.01e-03	377	82	5	25147182
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CSDE1 TBC1D9B INF2 RBBP4 POLR2B SHMT2 HCFC2 FIGNL1 ERLEC1 IPO11	2.05e-03	1440	82	10	30833792
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CSDE1 SEMA3F ITGA11 EFEMP1 PTPRK STC2 RBBP4 PTPRS ERLEC1	2.07e-03	1201	82	9	35696571
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	USO1 RBBP4 POLR2B CSTF3 SHMT2 IPO11	2.11e-03	560	82	6	35241646
Pubmed	Noggin is required for correct guidance of dorsal root ganglion axons.	EPHB3 SEMA3F	2.14e-03	29	82	2	12435358
Pubmed	Comprehensive proteomic analysis of the human spliceosome.	PAPOLA POLR2B CSTF3	2.22e-03	109	82	3	12226669
GeneFamily	Immunoglobulin like domain containing	SEMA3F AMIGO3 PTPRK CEACAM18 PECAM1	3.51e-04	193	57	5	594
GeneFamily	Olfactory receptors, family 2	OR2K2 OR2A7 OR2A4 OR2Z1	4.43e-04	113	57	4	149
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRK PTPRS	1.97e-03	21	57	2	813
GeneFamily	Olfactory receptors, family 13	OR13D1 OR13F1	2.37e-03	23	57	2	162
GeneFamily	Phosphodiesterases	PDE4B PDE10A	2.58e-03	24	57	2	681
GeneFamily	NLR family	NLRC5 NLRC3	2.80e-03	25	57	2	666
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SEMA3F PLEKHG1 CPXM2 STC2 LPAR6 PDE10A	1.73e-06	197	82	6	f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEMA3F PLEKHG1 CPXM2 STC2 LPAR6 PDE10A	1.73e-06	197	82	6	1a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA3F PLEKHG1 CPXM2 STC2 LPAR6 PDE10A	1.73e-06	197	82	6	96d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell	proximal-Endothelial-Bronchial_Vessel_1\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 CPXM2 STC2 LPAR6 PECAM1 LRRC70	1.89e-06	200	82	6	d034bd210c87b704acf45f50d888497c8737011b
ToppCell	proximal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 CPXM2 STC2 LPAR6 PECAM1 LRRC70	1.89e-06	200	82	6	0ff4185021ec84b57be13b28495e2f8a4d195eb6
ToppCell	proximal-Endothelial-Bronchial_Vessel_1-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 CPXM2 STC2 LPAR6 PECAM1 LRRC70	1.89e-06	200	82	6	e4f6e0b9502eb531f28d605f9dbda6a72a9ed320
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-NK-NK\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPN4 NHS NMUR1 NLRC3 SP140	1.57e-05	170	82	5	9a47d03f7eea6299a836a0eb1e7c1252c03f76df
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-NK-NK-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPN4 NHS NMUR1 NLRC3 SP140	1.57e-05	170	82	5	4252c0a335762508bd1f8f71c6e78a657d7df125
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-NK\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPN4 NHS NMUR1 NLRC3 SP140	1.57e-05	170	82	5	0aa11d8cb44403b6769860dac2d3b05da6fff79d
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIS12 AMIGO3 CEACAM18 HCFC2 FIGNL1	1.61e-05	171	82	5	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIS12 AMIGO3 CEACAM18 HCFC2 FIGNL1	1.61e-05	171	82	5	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	Control-Endothelial_cells-Systemic_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	SEMA3F PLEKHG1 STC2 PECAM1 PDE10A	1.66e-05	172	82	5	c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell	368C-Endothelial_cells-Endothelial-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F PLEKHG1 STC2 PECAM1 IPO11	1.80e-05	175	82	5	c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell	368C-Endothelial_cells-Endothelial-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F PLEKHG1 STC2 PECAM1 IPO11	1.80e-05	175	82	5	ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F PLEKHG1 STC2 PECAM1 PDE10A	2.06e-05	180	82	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F PLEKHG1 STC2 PECAM1 PDE10A	2.35e-05	185	82	5	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ENPP6 PTPRS FAT3 NHS PDE10A	2.60e-05	189	82	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	SEMA3F PLEKHG1 PTPRK PECAM1 PDE10A	2.67e-05	190	82	5	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TOX OR4D1 NLRC5 NMUR1 NLRC3	2.74e-05	191	82	5	6345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCell	(4)_Endothelial_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ENPP6 PLEKHG1 LPAR6 PECAM1 IPO11	2.88e-05	193	82	5	ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLEKHG1 PDE4B LPAR6 PECAM1 IPO11	2.88e-05	193	82	5	0f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCell	human_hepatoblastoma-NK.T_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	PDE4B TOX NLRC5 NLRC3 SP140	2.95e-05	194	82	5	997b02a22d7c89a8fd5615bb79a2a8a34fc3fee6
ToppCell	IPF-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	PLEKHG1 CPXM2 PTPRK STC2 PDE10A	3.02e-05	195	82	5	120296531bbc8080dcabacbd64733cc1dc34603a
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA3F PLEKHG1 CPXM2 PECAM1 PDE10A	3.02e-05	195	82	5	fde8e7b38b3631109b95ef111c5f6e3f9878cfbd
ToppCell	control-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PLEKHG1 FGD2 PTPRK SHMT2 SP140	3.02e-05	195	82	5	ddbc924b1a08685da0ed0755856178bae99a75b9
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	ENPP6 PLEKHG1 LPAR6 PECAM1 IPO11	3.02e-05	195	82	5	6b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F CPXM2 STC2 PECAM1 IPO11	3.18e-05	197	82	5	7caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F CPXM2 STC2 PECAM1 IPO11	3.18e-05	197	82	5	951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell	(6)_Endothelial-A_(Artery)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SEMA3F PLEKHG1 CPXM2 STC2 PECAM1	3.25e-05	198	82	5	44f8cd5afa3685dcc8bfea0b15af5e8817e12e2e
ToppCell	distal-1-Endothelial-Bronchial_Vessel_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 CPXM2 STC2 LPAR6 LRRC70	3.25e-05	198	82	5	5cd81fe1a21c0e1a7f0d5a62ddf8e422b05aedc7
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHG1 AMIGO3 CPXM2 PECAM1 PDE10A	3.33e-05	199	82	5	e2d5c5cab102e67b0131b02392d81adaedc15965
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHG1 CPXM2 STC2 PECAM1 PDE10A	3.33e-05	199	82	5	6fb81388c5045e81c3849a7136bdff3f953f044e
ToppCell	proximal-Endothelial\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 STC2 LPAR6 PECAM1 LRRC70	3.41e-05	200	82	5	970dac1b11ae8f4adb26634717064289967b4bde
ToppCell	proximal-3-Endothelial\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 STC2 LPAR6 PECAM1 LRRC70	3.41e-05	200	82	5	90c36cfb9632a3bdc9a335b2193f6b08aba35208
ToppCell	proximal-Endothelial-Bronchial_Vessel_2-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 STC2 LPAR6 PECAM1 PDE10A	3.41e-05	200	82	5	b6666ade237c39bfde13987685567bad1762baec
ToppCell	proximal-Endothelial-Bronchial_Vessel_2\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 STC2 LPAR6 PECAM1 PDE10A	3.41e-05	200	82	5	2ecf7a38799c151ffb09f2677e38a4ffa354c1da
ToppCell	severe-B_intermediate\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PLEKHG1 PDE4B FGD2 PTPRK SP140	3.41e-05	200	82	5	6d0ac3d00400dd5657ee266f7b885381bf790ce1
ToppCell	proximal-3-Endothelial-Bronchial_Vessel_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLEKHG1 STC2 LPAR6 PECAM1 PDE10A	3.41e-05	200	82	5	038812912bb9f6c1359765614bb9fd138843a306
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAT3 ASPM MROH7 ADGRV1	8.66e-05	126	82	4	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAT3 ASPM MROH7 ADGRV1	8.66e-05	126	82	4	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 STC2 PECAM1 PDE10A	1.49e-04	145	82	4	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRK NLRC5 NHS ADGRV1	1.88e-04	154	82	4	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STC2 PAPOLB NMUR1 NLRC3	2.28e-04	162	82	4	04ccd3d216f8f41afd3434a61264f03d6324db35
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	PTPN4 PDE4B LPAR6 PECAM1	2.33e-04	163	82	4	d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCell	PSB-critical-LOC-Lymphoid-PC\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE4B ASPM SHMT2 SP140	2.39e-04	164	82	4	3e672124dea2497c5bdf8a315c8cfacfab5780dc
ToppCell	Endothelial-endothelial_cell_of_bronchial_vessel\|World / Lineage, Cell type, age group and donor	PLEKHG1 SLC16A14 PECAM1 PDE10A	2.44e-04	165	82	4	84e553d699ac56df89a77248f7308b9133e1b683
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANTXRL TOX NIM1K NLRC3	2.67e-04	169	82	4	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANTXRL PDE4B FGD2 SP140	2.74e-04	170	82	4	a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRIM1 ASPM NMUR1 FIGNL1	2.74e-04	170	82	4	b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPN4 DTWD2 PRIM1 NLRC5	2.74e-04	170	82	4	070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	SEMA3F PLEKHG1 PECAM1 NMUR1	2.80e-04	171	82	4	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TOX PRIM1 FIGNL1 NLRC3	2.86e-04	172	82	4	4bdcf1ae2a1cfba0272c54072e37fb7958904321
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ENPP6 PTPN4 SETD6 PECAM1	2.92e-04	173	82	4	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TOX PTPRK PTPRS NIM1K	2.92e-04	173	82	4	ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TOX PTPRK PTPRS NIM1K	2.99e-04	174	82	4	110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TOX PECAM1 LRRC70 IPO11	3.05e-04	175	82	4	2e54961846c65b185d9bd6e305dd81205579d890
ToppCell	IIF-Lymphocyte-B-B_intermediate\|IIF / Disease, Lineage and Cell Type	PLEKHG1 PDE4B FGD2 SP140	3.05e-04	175	82	4	327f8ee3669c3fc5ba50abc3b4f3e068637fd8d8
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TOX PECAM1 LRRC70 IPO11	3.05e-04	175	82	4	efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCell	Endothelial-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	PLEKHG1 CPXM2 LRRC70 IPO11	3.12e-04	176	82	4	b288116a4588a1f9db9d49af92cea118937c9201
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLEKHG1 PDE4B PECAM1 GPR45	3.12e-04	176	82	4	96779273b94345250cf53ba671203345b43d9e00
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPN4 EFEMP1 ZSCAN31 PECAM1	3.19e-04	177	82	4	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	STC2 SLC16A14 PECAM1 PDE10A	3.19e-04	177	82	4	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRS FAT3 PECAM1 RNASE12	3.19e-04	177	82	4	c1f838e425ebb04482829b1957e3c1347127e6de
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 STC2 PECAM1 PDE10A	3.33e-04	179	82	4	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F PLEKHG1 PECAM1 OR8K3	3.33e-04	179	82	4	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	TOX PTPRK NIM1K ADGRV1	3.40e-04	180	82	4	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	ITGA11 CPXM2 FAT3 NHS	3.40e-04	180	82	4	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRS FAT3 PECAM1 RNASE12	3.40e-04	180	82	4	41e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	SEMA3F PLEKHG1 PECAM1 PDE10A	3.47e-04	181	82	4	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	facs-BAT-Fat-18m\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4B LPAR6 PECAM1 SP140	3.54e-04	182	82	4	efc335f4e566533cfbcd17262bd94ae64fa2e117
ToppCell	RA-17._Lymphocyte\|RA / Chamber and Cluster_Paper	TOX NLRC5 NLRC3 SP140	3.54e-04	182	82	4	257a7847917b6ea1d60608183d90300bfd028758
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPAR6 PECAM1 ASPM LRRC70	3.62e-04	183	82	4	52af3c943116073c8ddd207b664342960b88929b
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FGD2 PRIM1 FIGNL1 SP140	3.62e-04	183	82	4	956ff95aef9c5521b6a3ba7ac6df0aad242c1c35
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRIM1 ASPM FIGNL1 NLRC3	3.62e-04	183	82	4	769a022fe8568ec49e66f792cc5777e713a7571c
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PLEKHG1 FGD2 PTPRK SP140	3.62e-04	183	82	4	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PLEKHG1 FGD2 PTPRK SP140	3.62e-04	183	82	4	dbc7ec66da5930c2bf4e0405937b054e04c22a34
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3F CPXM2 STC2 PECAM1	3.62e-04	183	82	4	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLEKHG1 CPXM2 PECAM1 PDE10A	3.62e-04	183	82	4	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLEKHG1 PTPN4 STC2 PECAM1	3.62e-04	183	82	4	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRIM1 ASPM FIGNL1 NLRC3	3.62e-04	183	82	4	aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EFEMP1 TOX ASPM NMUR1	3.69e-04	184	82	4	ae0a77e3e520a246b17776bb19503519636b02ee
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F STC2 PRIM1 FIGNL1	3.69e-04	184	82	4	b998803180322a5ea2b567928dea531c26816c3c
ToppCell	droplet-Heart-4Chambers-21m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP6 PLEKHG1 PECAM1 IPO11	3.69e-04	184	82	4	f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EFEMP1 CPXM2 LRRC70 IPO11	3.69e-04	184	82	4	e5756afa3181186f9b65552b8df5359ef4024bee
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SEMA3F PLEKHG1 PECAM1 PDE10A	3.69e-04	184	82	4	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	COPD-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	PLEKHG1 CPXM2 STC2 PDE10A	3.77e-04	185	82	4	4abe04198ab5047c211f8d09cdb9650fa52a3cd6
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRIM1 ASPM FIGNL1 NLRC3	3.77e-04	185	82	4	0e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPAR6 PECAM1 LRRC70 IPO11	3.77e-04	185	82	4	a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRS PECAM1 RNASE12 MUC6	3.77e-04	185	82	4	5527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRIM1 ASPM FIGNL1 NLRC3	3.77e-04	185	82	4	89b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PLEKHG1 CPXM2 PECAM1 PDE10A	3.77e-04	185	82	4	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	PLEKHG1 STC2 PECAM1 PDE10A	3.77e-04	185	82	4	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PTPN4 TOX NLRC3 SP140	3.77e-04	185	82	4	593eceb3dfcc662c892a840ba29ab687c6886c01
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA3F CPXM2 PECAM1 PDE10A	3.77e-04	185	82	4	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F PLEKHG1 STC2 PECAM1	3.85e-04	186	82	4	f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PTPRK STC2 LPAR6 PECAM1	3.85e-04	186	82	4	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA3F TOX ASPM NMUR1	3.85e-04	186	82	4	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	COPD-Endothelial-VE_Peribronchial\|COPD / Disease state, Lineage and Cell class	PLEKHG1 CPXM2 STC2 PDE10A	3.85e-04	186	82	4	23c7d0e8372a71546d687278b985f761d282f92f
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PECAM1 ASPM LRRC70 IPO11	3.85e-04	186	82	4	e9d12f2fcd346fc8d00f7178324ea5997628df8a
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PTPRK STC2 LPAR6 PECAM1	3.85e-04	186	82	4	080e56113b89138277a2bd2eabddfa6cd1a18b61
Disease	brain connectivity measurement	SEMA3F PLEKHG1 ITGA11 FAT3 MKLN1 ADGRV1	5.09e-04	400	74	6	EFO_0005210
Disease	thalamus volume	SEMA3F FAT3 ADGRV1	1.29e-03	85	74	3	EFO_0006935
Disease	Malignant neoplasm of breast	OR12D3 TBC1D9B EFEMP1 STC2 MROH7 NLRC5 NHS MDM2 GPR45	1.44e-03	1074	74	9	C0006142
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	SEMA3F PDE4B	1.65e-03	24	74	2	EFO_0003948, EFO_0009923, MONDO_0004247
Disease	upper face morphology measurement	EFEMP1 ADGRV1 SP140	1.89e-03	97	74	3	EFO_0010949
Disease	executive function measurement	PLEKHG1 MIS12 CPXM2 PTPRK NLRC5	2.57e-03	376	74	5	EFO_0009332
Disease	diastolic blood pressure, alcohol drinking	PLEKHG1 PDE10A FER1L5	3.29e-03	118	74	3	EFO_0004329, EFO_0006336
Disease	age at first birth measurement	SEMA3F PDE4B TBC1D21	3.45e-03	120	74	3	EFO_0009101
Disease	high grade glioma (is_marker_for)	EFEMP1 ASPM	5.01e-03	42	74	2	DOID:3070 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ITFLRQVMALCTYPN	GPT2	106	Q8TD30
LKQNRPRSSTVMYIC	ERLEC1	201	Q96DZ1
MGRYRCTVENPVTQL	CEACAM18	291	A8MTB9
TVARFQSPNIRMCFI	ANTXRL	101	A6NF34
QMVYRVQEPLERSSC	ADGRV1	2356	Q8WXG9
MAYNITPLRRATVEC	CSDE1	666	O75534
LRLYCNTSVPAMRIA	AMIGO3	296	Q86WK7
ISSQYVIRMQPTNRC	DTWD2	206	Q8NBA8
PCMEVIRYAVQVLLN	ASPM	3311	Q8IZT6
VNEMCPNITRIYNIG	CPXM2	331	Q8N436
VNSCMGRVRRIYPQL	MROH7	851	Q68CQ1
RAMMIQTPSQYRFVC	PTPN4	891	P29074
QACTPMFREYSLQVL	SHMT2	341	P34897
AMLVARTCQLYPNAV	PAPOLB	251	Q9NRJ5
EYSRQCSMVGQPVRR	MUC6	276	Q6W4X9
LTTMAIDRYVAICNP	OR6K3	131	Q8NGY3
LRYQMIMTPRLCAQL	OR6K3	146	Q8NGY3
MVRALFAVARCQQPA	FIGNL1	481	Q6PIW4
IQDNPSQLVFMRIYC	HCFC2	721	Q9Y5Z7
SAVCMLVRPRALYNM	NMUR1	216	Q9HB89
LVRPRALYNMVVQTT	NMUR1	221	Q9HB89
VQADRALYLMCTVPA	NLRC3	316	Q7RTR2
CVIERVNMQIRPYVG	IPO11	586	Q9UI26
PLRYNCILTNSRVMN	OR51B4	126	Q9Y5P0
VCQPLQYPVLMRRQV	OR2Z1	126	Q8NG97
GYTTRNILCMPIVSR	PDE10A	361	Q9Y233
NRPLTCIMYAIFQER	PDE4B	361	Q07343
QIVVCEMLSQPRISY	PECAM1	401	P16284
TAVRRVYQRGCVNPM	CSTF3	166	Q12996
AMNPIRTYQVCNVRE	EPHB3	71	P54753
VDCLTLGQYMQPTRR	LIAS	301	O43766
PQQMIISRYLLSVCG	NPIPB5	601	A8MRT5
VNCSVVAAVRTMYPI	LPAR6	261	P43657
TVAPALQRCQTYMDI	ITGA11	151	Q9UKX5
TAMEYCQRVLRKPAQ	ITGA11	801	Q9UKX5
AVVDIAYACNTVPRM	OR2A7	66	Q96R45
AYACNTVPRMLVNLL	OR2A7	71	Q96R45
RNPLLYTTAMSQRLC	OR5C1	131	Q8NGR4
LQQIPTERYGIDCIM	NIM1K	306	Q8IY84
GNTVVCIIVYQRPAM	GPR45	51	Q9Y5Y3
CIIVYQRPAMRSAIN	GPR45	56	Q9Y5Y3
ELCIRLLQMPSVVNY	INF2	36	Q27J81
MRGRALRYINITNCV	LRRC70	391	Q7Z2Q7
ARVAVTCPTVRMLQA	NLRC5	791	Q86WI3
EVNRARYMPQNPCII	RBBP4	126	Q09028
LVNIMPYESTRVCLQ	PTPRS	1711	Q13332
AVVDIAYACNTVPRM	OR2A4	66	O95047
AYACNTVPRMLVNLL	OR2A4	71	O95047
FVAICNPLRYTVIMN	OR12D3	121	Q9UGF7
NPLRYTVIMNPQVCI	OR12D3	126	Q9UGF7
MLVARTCQLYPNAIA	PAPOLA	251	P51003
IMLQYCFPRLDINVS	PRIM1	296	P49642
FRPIIVALMARACNI	PDSS1	136	Q5T2R2
NGIIMYTRANPCIIL	FAT3	3871	Q8TDW7
NMLLYCVPRVIQVGA	FGD2	346	Q7Z6J4
APIRSVDVYNVMCNV	ENPP6	381	Q6UWR7
VPARYCNHMIIQRVI	RNASE12	41	Q5GAN4
RYVTIMNTQLCVGLV	OR4D1	131	Q15615
RICNLTRPQEGYLMV	PTPRK	1316	Q15262
RYTVIMNPRICVALA	OR10D3	131	Q8NH80
RYPVLMNGRLCTVLV	OR10G2	136	Q8NGC3
VAICNPLRYSIIMNG	OR13D1	156	Q8NGV5
RYPVIMNRRTCVQIA	OR13F1	131	Q8NGS4
ICNPLRYSIIMNRCV	OR2K2	126	Q8NGT1
VSNAMCRELPQSIVY	EFEMP1	381	Q12805
SMVNERQPFVLRCAV	USO1	371	O60763
MCTYVNRGRRAQATP	SEMA3F	141	Q13275
MRTPTNCYLVSLAVA	TRHR	56	P34981
PCRNFQVLVAYSMLQ	TBC1D21	266	Q8IYX1
CLVRVYMVRAINLQP	FER1L5	1486	A0AVI2
SVRCRLYNTPMQAIS	NHS	1616	Q6T4R5
QPCIRIIEQSRRKYM	SLC16A14	491	Q7RTX9
MCIDIQRRQIYTLGR	MKLN1	331	Q9UL63
SRRYQQTMGSLQPLC	TAF1	121	P21675
PVCRQPIQMIVLTYF	MDM2	476	Q00987
RNKTQISLVRMPYAC	POLR2B	1141	P30876
EYSANCLRMVATQPI	SETD6	261	Q8TBK2
MSRRVCIQLVAVPYI	OR8U3	136	Q8NH85
MSRRVCQVLVAIPYL	OR8K3	136	Q8NH51
RYPVIMTNQLCGTLA	OR6Y1	136	Q8NGX8
ISVVYLRCPEMVENR	RIG	71	Q13278
RNPTIGYCQAMNIVT	TBC1D9B	586	Q66K14
QLQPMVTQLRYESFC	ZSCAN31	156	Q96LW9
TPQTCMLRIYIAFQD	MIS12	16	Q9H081
KRMSECPICRQYVVR	RNF34	351	Q969K3
PAIREMVSQLQRECY	STC2	126	O76061
RNLVPVTRVMYCVLS	SP140	86	Q13342
TNYPRSVAVLTECMR	PLEKHG1	206	Q9ULL1
VTQAMEYVRSGCRNP	TOX	486	O94900
RLAQAQSMCLPIYRE	GRIN2C	1116	Q14957