Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessprotein K27-linked ubiquitination

UBE2D2 UBE2D3 UBR4 UBE2D4

8.28e-06142024GO:0044314
Domain-

PSG2 CADM4 SIRPG NEO1 PVR ASTN2 TRIM36 USH2A CNTFR CDON FLT1 TNC FSD2 BTLA PKHD1L1 CD8B SIGLEC6 VCAN PLXNA4 CNTN3 TGM7

6.32e-06663195212.60.40.10
DomainIg-like_fold

PSG2 CADM4 SIRPG NEO1 PVR ASTN2 TRIM36 USH2A CNTFR CDON FLT1 TNC FSD2 BTLA PKHD1L1 CD8B SIGLEC6 VCAN PLXNA4 CNTN3 TGM7

1.63e-0570619521IPR013783
DomainWD40_repeat_dom

DCAF8 NBEAL1 DDB1 MAPK8IP3 CDC40 POC1B WDFY1 UBR4 NBEA WDPCP DNAI1 TENM3

7.05e-0529719512IPR017986
DomainFN3

NEO1 ASTN2 TRIM36 USH2A CNTFR CDON TNC FSD2 CNTN3

1.45e-041851959SM00060
Domainig

PSG2 SIRPG PVR CNTFR CDON FLT1 BTLA SIGLEC6 CNTN3

1.77e-041901959PF00047
DomainImmunoglobulin

PSG2 SIRPG PVR CNTFR CDON FLT1 BTLA SIGLEC6 CNTN3

1.77e-041901959IPR013151
Domain-

DCAF8 NBEAL1 DDB1 MAPK8IP3 CDC40 POC1B SEMA6A WDFY1 NBEA WDPCP DNAI1 PLXNA4

2.06e-04333195122.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF8 NBEAL1 DDB1 MAPK8IP3 CDC40 POC1B SEMA6A WDFY1 NBEA WDPCP DNAI1 PLXNA4

2.17e-0433519512IPR015943
DomainFN3

NEO1 ASTN2 TRIM36 USH2A CNTFR CDON TNC FSD2 CNTN3

2.50e-041991959PS50853
DomainIg_V-set

PSG2 CADM4 SIRPG PVR FLT1 CD8B SIGLEC6 VCAN CNTN3

2.50e-041991959IPR013106
Domainfn3

NEO1 TRIM36 USH2A CNTFR CDON TNC FSD2 CNTN3

3.07e-041621958PF00041
DomainFN3_dom

NEO1 ASTN2 TRIM36 USH2A CNTFR CDON TNC FSD2 CNTN3

3.59e-042091959IPR003961
DomainIG

PSG2 CADM4 SIRPG NEO1 PVR CNTFR CDON FLT1 BTLA CD8B SIGLEC6 VCAN CNTN3

4.99e-0442119513SM00409
DomainIg_sub

PSG2 CADM4 SIRPG NEO1 PVR CNTFR CDON FLT1 BTLA CD8B SIGLEC6 VCAN CNTN3

4.99e-0442119513IPR003599
DomainCH

SPTB SPTBN1 ACTN4 NAV3 LMO7

5.86e-04651955SM00033
DomainSpectrin_bsu

SPTB SPTBN1

6.42e-0441952IPR016343
DomainV-set

PSG2 CADM4 SIRPG PVR CD8B SIGLEC6 VCAN CNTN3

7.15e-041841958PF07686
DomainCH

SPTB SPTBN1 ACTN4 NAV3 LMO7

8.23e-04701955PF00307
Domain-

SAMD9 ZGRF1 CHD1 ABCB4 SUPV3L1 ABCC8 SHPRH NAV3 DNAH6 CARD14 EP400 SEPTIN5 DDX51 MSH4 RHEB ORC4 DDX20 AQR

8.50e-04746195183.40.50.300
Domain-

SPTB SPTBN1 ACTN4 NAV3 LMO7

8.78e-047119551.10.418.10
DomainHelicase_C

CHD1 SUPV3L1 SHPRH EP400 DDX51 DDX20

9.05e-041071956PF00271
DomainHELICc

CHD1 SUPV3L1 SHPRH EP400 DDX51 DDX20

9.05e-041071956SM00490
DomainHelicase_C

CHD1 SUPV3L1 SHPRH EP400 DDX51 DDX20

9.50e-041081956IPR001650
DomainCH

SPTB SPTBN1 ACTN4 NAV3 LMO7

9.96e-04731955PS50021
DomainHELICASE_CTER

CHD1 SUPV3L1 SHPRH EP400 DDX51 DDX20

9.97e-041091956PS51194
DomainHELICASE_ATP_BIND_1

CHD1 SUPV3L1 SHPRH EP400 DDX51 DDX20

9.97e-041091956PS51192
DomainDUF4704

NBEAL1 NBEA

1.06e-0351952IPR031570
DomainDUF4704

NBEAL1 NBEA

1.06e-0351952PF15787
DomainCH-domain

SPTB SPTBN1 ACTN4 NAV3 LMO7

1.13e-03751955IPR001715
Pubmed

Ubiquitination of STING at lysine 224 controls IRF3 activation.

UBE2D2 UBE2D3 MUL1 UBE2D4

7.58e-0713202428763789
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

ITGA6 ACTN4 FAT1 PI4KA PVR PIP5K1A VASP HSPA9 FLT1 TNC LMO7

1.01e-062852021121423176
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

CYP1B1 ACTN4 SQOR DDB1 DDOST FAT1 NEO1 NDUFA12 PRDX3 PVR PIP5K1A NID1 LOXL3 DNAH6 HSPA9 CERS2 COX7A2P2 CP CPT2 TMBIM6 ASH2L RHEB RSBN1 FRRS1 MEPCE

1.29e-0614512022530550785
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SAMD9 C15orf39 DDOST RUSC2 TYK2 FREM2 CDC40 SUPV3L1 PIP5K1A KYNU MGRN1 NOL9 ASH2L JMJD1C IBTK AQR

1.49e-066502021638777146
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

FREM2 NID1 COL4A6 TNC

1.90e-0616202415878328
Pubmed

The RING domain of mitochondrial E3 ubiquitin ligase 1 and its complex with Ube2D2: crystallization and X-ray diffraction.

UBE2D2 UBE2D3 MUL1

1.91e-065202331929179
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

NID1 CDON TNC LAMA2 APOB VCAN

2.02e-0664202622261194
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

ZNF235 SQOR SHPRH MED12L HSPA9 FLT1 INTS7 JMJD1C IBTK TENM3 LMO7 EIF4E

2.05e-063712021215747579
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

DDB1 PRDX3 SIPA1L2 HSPA9 CARD14 EP400 UBR4 ZBTB47 IBTK RESF1 DDX20 PRORP

3.99e-063962021226687479
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

CYP1B1 GBF1 NT5C3A ITGA6 FAT1 NEO1 NDUFA12 PVR MUL1 KYNU TNFSF15 VASP HSPA9 MGRN1 CERS2 APOB RHEB ORC4 LMO7 C15orf61

4.31e-0610612022033845483
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

SPTBN1 ACTN4 SQOR DDB1 PI4KA NAV3 CC2D2A C3 HSPA9 EP400 FAM83H VPS13D FRRS1 VCAN

6.24e-065642021421565611
Pubmed

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

UBE2D2 UBE2D3 UBE2D4

6.64e-067202321685362
Pubmed

Analysis of the Zn-Binding Domains of TRIM32, the E3 Ubiquitin Ligase Mutated in Limb Girdle Muscular Dystrophy 2H.

UBE2D2 UBE2D3 UBE2D4

6.64e-067202330884854
Pubmed

Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome.

ITGA6 TNC RP1

6.64e-067202311767049
Pubmed

Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress.

UBE2D2 UBE2D3 TMBIM6

6.64e-067202321068390
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

CYP1B1 MAK DCAF8 ACP5 SPTBN1 SNRK ACTN4 DDOST FAT1 RRP7A C3 CA1 TNC BBS5 CUBN ORC4 VCAN ZNF566 MEPCE NIPAL2 DEPDC5 PRORP

7.14e-0612932022215342556
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

SPTBN1 DDB1 SHPRH NID1 FLT1 HTR2B FNBP4 NBEA DNAI1 VPS13D LMO7 MEPCE RP1

7.74e-064972021336774506
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

GBF1 ELP6 CYP46A1 FCHO1 FAT1 DNAH6 UBR4 CALCOCO1 JMJD1C MICU3 LMO7

9.63e-063612021126167880
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRPM6 GBF1 ZNF280D SPTBN1 CHD1 ACTN4 DDB1 DDOST HNRNPL CDC40 SUPV3L1 PI4KA PRDX3 CC2D2A RRP7A NOP2 HSPA9 UBR4 APOB NOL9 EIF4E DDX20 AQR

1.02e-0514252022330948266
Pubmed

Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.

UBE2D2 UBE2D3 UBE2D4

1.06e-058202328681414
Pubmed

Ube2W conjugates ubiquitin to α-amino groups of protein N-termini.

UBE2D2 UBE2D3 UBE2D4

1.06e-058202323560854
Pubmed

Inhibition of UVSSA ubiquitination suppresses transcription-coupled nucleotide excision repair deficiency caused by dissociation from USP7.

UBE2D2 UBE2D3 UBE2D4

1.06e-058202329323787
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

DDB1 CEP350 PIP5K1A SIPA1L2 INTS7 JMJD1C ORC4 MEPCE DDX20

1.33e-05242202934011540
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TRPM6 SPTBN1 ACTN4 ALKBH8 KCNH1 PI4KA WDFY1 CERS2 BTLA APOB NOL9 CUBN CPT2 TMBIM6 ASH2L ORC4 RESF1 VCAN TRAPPC10

2.07e-0510842021911544199
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

FREM2 NEO1 PVR C3 TNC LAMA2 CP APOB CNTN3

2.13e-05257202916335952
Pubmed

Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome.

UBE2D2 UBE2D3 UBE2D4

2.25e-0510202331087003
Pubmed

Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells.

UBE2D2 UBE2D3 UBE2D4

2.25e-0510202328757353
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

NBEAL1 HNRNPL CAPN13 FREM2 DCANP1 FAT1 PVR ERVK-25 COL4A6 FLT1 BTLA LMO7 ZFHX2

2.33e-055522021310737800
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

DCAF8 SPTBN1 HNRNPL PI4KA NAV3 NID1 C3 NOP2 CACNA1B INTS7 UBR4 DDX20

2.45e-054752021231040226
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

ITGA6 FAT1 NEO1 SEMA6A

3.07e-0531202411431694
Pubmed

Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2.

DCAF8 DDB1 UBE2D3

3.08e-0511202337379210
Pubmed

Monoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligase.

DDB1 UBE2D2 UBE2D3

3.08e-0511202322334663
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DPP10 EP400 PHF12 CALCOCO1 TENM3 CNTN3

3.19e-05103202610819331
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CC2D2A SEMA6A SIPA1L2 WDFY1 UBR4 JMJD1C IBTK

3.33e-05153202710718198
Pubmed

Accumulation of p53 via down-regulation of UBE2D family genes is a critical pathway for cadmium-induced renal toxicity.

UBE2D2 UBE2D4

3.36e-052202226912277
Pubmed

Involvement of tenascin-C and PG-M/versican in flexor tenosynovial pathology of idiopathic carpal tunnel syndrome.

TNC VCAN

3.36e-052202216493581
Pubmed

Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

CD8B CD8B2

3.36e-05220223035575
Pubmed

Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

CD8B CD8B2

3.36e-05220223498943
Pubmed

An immunological role for the CD8 beta-chain.

CD8B CD8B2

3.36e-05220221534146
Pubmed

[Semaphorin/plexin signal regulates lamina-restricted projection of hippocampal mossy fiber].

SEMA6A PLXNA4

3.36e-052202221089322
Pubmed

Duality of the murine CD8 compartment.

CD8B CD8B2

3.36e-052202224594598
Pubmed

Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.

CD8B CD8B2

3.36e-05220227889415
Pubmed

AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas.

CD8B CD8B2

3.36e-05220223025647
Pubmed

Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.

CD8B CD8B2

3.36e-05220222452747
Pubmed

Distinct methylation states of the CD8 beta gene in peripheral T cells and intraepithelial lymphocytes.

CD8B CD8B2

3.36e-05220229233619
Pubmed

Genetic Variability in the Iron Homeostasis Pathway and Patient Outcomes After Aneurysmal Subarachnoid Hemorrhage.

CP CUBN

3.36e-052202232246437
Pubmed

Stalk region of beta-chain enhances the coreceptor function of CD8.

CD8B CD8B2

3.36e-052202212847256
Pubmed

The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.

APOF APOB

3.36e-052202222363685
Pubmed

Complement 3 deficiency and oral prednisolone improve strength and prolong survival of laminin alpha2-deficient mice.

C3 LAMA2

3.36e-052202212044978
Pubmed

Transcriptional diversity at the duplicated human CD8 beta loci.

CD8B CD8B2

3.36e-05220228436166
Pubmed

Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling.

UBE2D2 MUL1

3.36e-052202218213395
Pubmed

Structure and expression of the Lyt-3a gene of C.AKR mice.

CD8B CD8B2

3.36e-05220223169881
Pubmed

Esr, a second locus in the house mouse controlling esterase-5.

CD8B CD8B2

3.36e-05220227103930
Pubmed

The phosphatidylinositol 4-kinase PI4KIIIalpha is required for the recruitment of GBF1 to Golgi membranes.

GBF1 PI4KA

3.36e-052202220530568
Pubmed

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.

PI4KA PIP5K1A

3.36e-052202227870828
Pubmed

Exome sequencing in patients with microphthalmia, anophthalmia, and coloboma (MAC) from a consanguineous population.

CDON TENM3

3.36e-052202232799327
Pubmed

Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.

CD8B CD8B2

3.36e-05220225558567
Pubmed

Cloning and modeling of CD8 beta in the amphibian ambystoma Mexicanum. Evolutionary conserved structures for interactions with major histocompatibility complex (MHC) class I molecules.

CD8B CD8B2

3.36e-052202212034498
Pubmed

Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer.

SEMA6A PLXNA4

3.36e-052202234815265
Pubmed

Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.

CD8B CD8B2

3.36e-05220228108731
Pubmed

Murine Ly-3 restriction fragment length polymorphism and transcript size differences.

CD8B CD8B2

3.36e-05220222576243
Pubmed

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.

CD8B CD8B2

3.36e-05220229647223
Pubmed

The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.

CD8B CD8B2

3.36e-0522022408079
Pubmed

Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion.

APOB TMBIM6

3.36e-052202227297735
Pubmed

Characterization of the mouse CD8 beta chain-encoding gene promoter region.

CD8B CD8B2

3.36e-05220228781121
Pubmed

Expression of extracellular matrix components versican, chondroitin sulfate, tenascin, and hyaluronan, and their association with disease outcome in node-negative breast cancer.

TNC VCAN

3.36e-052202215073129
Pubmed

Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons.

DCAF8 DDB1

3.36e-052202224500646
Pubmed

Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction.

CYP1B1 C3 KYNU HTR2B TNC CP

3.56e-05105202624667918
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SPTBN1 SPIN4 HNRNPL BRCA2 FIG4 PI4KA PRDX3 SHPRH NOP2 FLG EP400 INTS7 APOB NOL9 GSTM2

3.88e-057542021535906200
Pubmed

The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules.

SPTBN1 ACTN4 POF1B NOP2 LMO7

3.91e-0565202532521226
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GAD2 SPTBN1 SNRK ACTN4 RTN1 MAPK8IP3 NEO1 NDUFA12 PI4KA NAV3 SIPA1L2 HSPA9 CACNA1B MAPK8IP1 SEPTIN5 UBR4 NBEA RHEB MICU3

4.05e-0511392021936417873
Pubmed

MRG15 is a novel PALB2-interacting factor involved in homologous recombination.

BRCA2 EP400 PHF12

4.09e-0512202319553677
Pubmed

The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes.

UBE2D2 UBE2D3 UBE2D4

4.09e-0512202324211586
Pubmed

Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.

SEMA6A FLT1 VCAN PLXNA4

5.02e-0535202428172500
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DCAF8 SPTB BLNK ADARB1 HNRNPL MAPK8IP3 TYK2 ABCC8 PVR SHPRH PIP5K1A ASTN2 SEMA6A TET3 MAML3 MGRN1 SEPTIN5 CALCOCO1 FNBP4 JMJD1C ZFHX2 PRORP

6.04e-0514892022228611215
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CYP1B1 CHD1 SQOR RFTN1 NDUFA12 PI4KA RRP7A TAF1L CERS2 EP400 SEPTIN5 INTS7 PHF12 DDX51 NOL9 ASH2L ORC4 RSBN1 GPBP1L1 EIF4E DDX20 AQR

6.53e-0514972022231527615
Pubmed

Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity.

UBE2D2 UBE2D3 UBE2D4

6.70e-0514202336481767
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SQOR DDB1 DDOST HNRNPL CDC40 RRP7A NOP2 TAF1L TET3 HSPA9 CERS2 EP400 INTS7 PHF12 FNBP4 DDX51 NOL9 ASH2L JMJD1C LMO7

7.24e-0512942022030804502
Pubmed

Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes.

DDB1 UBE2D2 UBE2D3

8.34e-0515202317452440
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

ZNF280D CHD1 HNRNPL HSPA9 PHF12 ORC4

9.01e-05124202620850016
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

CHD1 DDOST HNRNPL UBE2D3 CDC40 RRP7A NOP2 HSPA9 CA1 EP400 UBR4 NOL9 USP16 RHEB FAM83H ORC4 RSBN1 MEPCE DDX20 AQR

9.29e-0513182022030463901
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SPTB SPTBN1 ACTN4 DDB1 RTN1 MAPK8IP3 NDUFA12 PI4KA SIPA1L2 DNAH6 HSPA9 MAPK8IP1 SEPTIN5 TNC CALCOCO1 NBEA LMO7 VCAN EIF4E PLXNA4 TRAPPC10

9.85e-0514312022137142655
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTB SPTBN1

1.00e-043202211294830
Pubmed

Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.

SEMA6A PLXNA4

1.00e-043202217296555
Pubmed

Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.

CD8B CD8B2

1.00e-04320223258885
Pubmed

Ly-36: a new mouse lymphocyte alloantigen defined by a Mus musculus molossinus-specific monoclonal antibody and controlled by a gene linked to Ly-2/3 region on chromosome 6.

CD8B CD8B2

1.00e-04320223378837
Pubmed

Evidence for close linkage of a mouse light chain marker with the Ly-2,3 locus.

CD8B CD8B2

1.00e-0432022100557
Pubmed

Distribution of dystroglycan in normal adult mouse tissues.

ITGA6 LAMA2

1.00e-04320229524190
Pubmed

Interaction of the nuclear matrix-associated region (MAR)-binding proteins, SATB1 and CDP/Cux, with a MAR element (L2a) in an upstream regulatory region of the mouse CD8a gene.

CD8B CD8B2

1.00e-04320229218488
Pubmed

MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate.

UBE2D2 MUL1

1.00e-043202235048531
Pubmed

Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway.

MAPK8IP3 MAPK8IP1

1.00e-043202234014261
Pubmed

Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells.

CD8B CD8B2

1.00e-043202212810689
Pubmed

Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.

SEMA6A PLXNA4

1.00e-043202222777942
Pubmed

A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice.

CD8B CD8B2

1.00e-04320229126989
Pubmed

CD8 binding to MHC class I molecules is influenced by T cell maturation and glycosylation.

CD8B CD8B2

1.00e-043202211754824
Pubmed

Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine.

ITGA6 LAMA2

1.00e-04320227803849
Pubmed

The synthesis and processing of beta-glucuronidase in normal and egasyn deficient mouse kidney.

CD8B CD8B2

1.00e-04320227236294
Pubmed

An essential role for the stalk region of CD8 beta in the coreceptor function of CD8.

CD8B CD8B2

1.00e-043202219109142
Pubmed

Recombination between kappa chain genetic markers in the mouse.

CD8B CD8B2

1.00e-04320226437974
Pubmed

Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.

CD8B CD8B2

1.00e-04320228064243
InteractionARK2C interactions

HNRNPL UBE2D2 UBE2D3 UBE2D4

4.21e-06121984int:ARK2C
GeneFamilyFibronectin type III domain containing

NEO1 ASTN2 TRIM36 USH2A CNTFR CDON TNC FSD2 CNTN3

3.21e-061601359555
GeneFamilyImmunoglobulin like domain containing

CADM4 NEO1 PVR CNTFR CDON FLT1 BTLA CNTN3

1.02e-041931358594
GeneFamilyAdenosine receptors|V-set domain containing

PSG2 CADM4 SIRPG PVR CD8B SIGLEC6 VCAN

2.24e-041631357590
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN1

1.13e-03713521113
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 NBEA

1.93e-03913521230
CoexpressionPARENT_MTOR_SIGNALING_UP

SAMD9 GBF1 CYP46A1 RTN1 CEP350 CDC40 PI4KA CALCOCO1 LAMA2 CP CPT2 TMBIM6 RHEB VPS13D RESF1 DEPDC5

6.67e-0656719716M16909
CoexpressionGSE13306_TREG_VS_TCONV_UP

BLNK RUSC2 ASTN2 UPK2 USH2A CNTFR CACNA1B GSTM2 RESF1

2.01e-051981979M3229
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_DN

ACTN4 DDB1 HNRNPL FREM2 FAT1 KCNH1 VASP CACNA1B GSTM2

2.18e-052001979M7350
CoexpressionDELACROIX_RAR_TARGETS_UP

BLNK TYK2 NID1 CP RESF1

2.71e-05471975M2464
CoexpressionDELACROIX_RAR_TARGETS_UP

BLNK TYK2 NID1 CP RESF1

3.32e-05491975MM1078
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP

CYP1B1 UBE2D2 NID1 C3 TNC LMO7 VCAN

3.73e-051211977M12828
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 FAT1 MAST4 LIPH CA1 DPP10 CP NBEA LMO7 CNTN3 RP1

7.38e-111912001223776c7302cead3881b39127398f3b3e0d27885e
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 FAT1 MAST4 LIPH CA1 DPP10 CP NBEA PLXNA4 CNTN3

6.23e-1018020011b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 FREM2 FAT1 MAST4 LIPH CFAP221 LMO7 CNTN3 RP1

1.18e-0818420010102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

CAPN13 FAT1 MAST4 CDON DPP10 CP NBEA CUBN PLXNA4 CNTN3

1.37e-0818720010ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 RTN1 CAPN13 FAT1 C3 COL4A6 TNC CP GSTM2 TENM3

1.52e-0818920010319e42f6e2322208de78bc666fb2c074707eb4da
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 FAT1 MAST4 LIPH DPP10 CP NBEA PLXNA4 CNTN3

1.60e-0819020010756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 FAT1 MAST4 LIPH CP NBEA LMO7 CNTN3 RP1

1.85e-08193200102bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SPTBN1 PERP MAST4 LIPH CFAP221 DNAH6 NBEA DNAI1 LMO7 RP1

2.04e-0819520010fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SPTBN1 PERP MAST4 LIPH CFAP221 DNAH6 NBEA DNAI1 LMO7 RP1

2.04e-0819520010eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 FAT1 MAST4 LIPH DPP10 CP NBEA LMO7 CNTN3 RP1

2.04e-0819520010dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 FAT1 LIPH CP NBEA LMO7 CNTN3 RP1

1.44e-071822009215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 RTN1 CAPN13 FAT1 C3 COL4A6 TNC CP TENM3

2.08e-071902009050d6e0546954675b6adbfecb67854b1e09739d1
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

CYP1B1 RFTN1 FAT1 TNC CP TMBIM6 GSTM2 RESF1 LMO7

2.17e-07191200978ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ACP5 PEX12 FAT1 PVR C3 DNAH6 CDON MGRN1 CP

2.82e-0719720096b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2B6 CAPN13 FAT1 MAST4 LIPH CP LMO7 CNTN3 RP1

2.94e-0719820091408e02e053ad3406229bfe8189da03be6366e81
ToppCellCOVID-19-kidney-Fibroblast-2|kidney / Disease (COVID-19 only), tissue and cell type

CYP1B1 RFTN1 NAV3 NID1 TNC LAMA2 MSRB3 TENM3 VCAN

2.94e-071982009ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell343B-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CADM4 BLNK NME8 SIRPG ZNF596 P2RX1 SIGLEC6 PLXNA4

1.00e-061692008632aa3ab39ec87bafcefec6cddf71129a054d3b0
ToppCell343B-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CADM4 BLNK SIRPG ZNF596 CALCOCO1 P2RX1 SIGLEC6 PLXNA4

1.30e-061752008b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

CEP350 MAST4 UBR4 PAPOLG VPS13D FRRS1 NIPAL2

1.34e-0612220071ed865f0ecfe304fb86313ff51c04e9052357270
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

CYP2B6 FAT1 LIPH CFAP221 CA1 CP LMO7 RP1

1.36e-0617620083fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 FAT1 NEO1 PGLYRP4 CP PLXNA4 CNTN3

1.42e-061772008d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

RFTN1 C3 SIPA1L2 TNC CP MSRB3 TENM3 VCAN

1.54e-061792008e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 RFTN1 FAT1 NAV3 SIPA1L2 TNC TENM3 VCAN

1.68e-0618120085f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 RFTN1 FAT1 NAV3 SIPA1L2 TNC TENM3 VCAN

1.68e-061812008c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CADM4 BLNK CYP46A1 NME8 KCTD19 MSRB3 SIGLEC6 PLXNA4

1.75e-0618220089bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CADM4 BLNK CYP46A1 NME8 KCTD19 MSRB3 SIGLEC6 PLXNA4

1.75e-0618220084602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

CYP2B6 CAPN13 MAST4 LIPH DPP10 CP LMO7 RP1

1.98e-061852008cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell15-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

PERP FREM2 LIPH UPK2 TRIM36 CP LMO7 RP1

2.23e-0618820089a64fb07de611de38d6f24673feb3b81a5e85384
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 NAV3 NID1 CDON LAMA2 MSRB3 TENM3 VCAN

2.60e-0619220085105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 NID1 C3 LOXL3 CNTFR CDON LAMA2 VCAN

2.60e-061922008a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 CHD1 NID1 C3 CNTFR LAMA2 JMJD1C VCAN

2.60e-06192200811088878043a6ff95ba1970361256a82e434b80a
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 NID1 C3 LOXL3 CNTFR CDON LAMA2 VCAN

2.60e-061922008eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 NAV3 C3 CNTFR CDON LAMA2 CP MSRB3

2.92e-0619520083c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SPTBN1 PERP MAST4 CFAP221 DNAH6 DNAI1 LMO7 RP1

3.03e-0619620086d02d494196e3f857d53eea46d9419690d43beca
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 FAT1 NAV3 NID1 C3 LAMA2 CP TENM3

3.03e-0619620086bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 FAT1 NAV3 NID1 C3 LAMA2 CP TENM3

3.03e-061962008c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Club|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CYP2B6 PERP FREM2 LIPH C3 UPK2 CP LMO7

3.03e-0619620084e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SPTBN1 PERP MAST4 CFAP221 DNAH6 DNAI1 LMO7 RP1

3.03e-061962008af4cdc61830685a888a1209826c23bcf54a43084
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BLNK CYP46A1 NME8 DCANP1 MED12L KCTD19 BTLA PLXNA4

3.15e-0619720083a5908deb5c5a2bf06019a102fb1652233cf2a2a
ToppCellsevere-dn_T|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ACP5 SPTBN1 ELP6 SIRPG FAT1 NDUFA12 IBTK CD8B

3.27e-061982008d4f2213af45ada47e6c62675f468ce05692db507
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

POF1B CAPN13 DPP10 CP NBEA GSDMC CNTN3 IFNE

3.27e-061982008af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2B6 CAPN13 MAST4 LIPH CP LMO7 CNTN3 RP1

3.27e-061982008af399569c718f5fd971d73a7926768c9311002a3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 FAT1 C3 SIPA1L2 FLG TNC TENM3 VCAN

3.40e-061992008b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CYP1B1 ADARB1 NID1 TNC CP TENM3 VCAN PLXNA4

3.40e-061992008a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 FAT1 C3 SIPA1L2 FLG TNC TENM3 VCAN

3.40e-061992008c972d3036151403f26fa9d6271520639c281ab84
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF280D ITGA6 RFTN1 NEO1 POC1B CALCOCO1 LMO7 NIPAL2

3.40e-0619920085db7c8089172ac8e796613b3cef618d87007a0ab
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TRPM6 CMBL FIG4 LIPH POC1B PGBD5 P2RX1 PRORP

3.52e-0620020080b02f3ca3d8612ed7af46381195b0ed5591313cf
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PERP ITGA6 CAPN13 MAST4 TNC CP NBEA LMO7

3.52e-062002008f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCell356C-Myeloid-Mast_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

SPTB MED12L PGBD5 NBEA IDS P2RX1 SIGLEC6

4.86e-0614820071668d8a9e680da335362744f36b05446c499347e
ToppCell356C-Myeloid-Mast_cell-|356C / Donor, Lineage, Cell class and subclass (all cells)

SPTB MED12L PGBD5 NBEA IDS P2RX1 SIGLEC6

4.86e-06148200718511ba10765eda937c5a710626361f7e6b9b321
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USH2A CACNA1B KCTD19 LAMA2 TEAD4 PKHD1L1 CNTN3

8.11e-061602007c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USH2A CACNA1B KCTD19 LAMA2 TEAD4 PKHD1L1 CNTN3

8.11e-06160200725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

GAD2 SQOR ADARB1 FSD2 CP GSTM2 CD8B

9.15e-061632007f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell10x5'-Liver-Myeloid_Dendritic-pDC|Liver / Manually curated celltypes from each tissue

CADM4 BLNK CYP46A1 KCTD19 MSRB3 P2RX1 SIGLEC6

1.03e-05166200724dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 NAV3 C3 CNTFR LAMA2 MSRB3 VCAN

1.11e-0516820074b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

CADM4 CYP46A1 NME8 KCTD19 MSRB3 P2RX1 SIGLEC6

1.11e-051682007cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID1 CNTFR LAMA2 MSRB3 TENM3 VCAN PLXNA4

1.16e-051692007a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 NAV3 C3 CNTFR LAMA2 MSRB3 VCAN

1.25e-0517120075d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NT5C3A SPTB ITGA6 ABCB4 MED12L PKD1L3 P2RX1

1.30e-051722007e39ea2f4edbf36ebf9604fa6f9349081859c596c
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

ADARB1 RFTN1 C3 SIPA1L2 TNC TENM3 VCAN

1.30e-05172200736a96714a0eb6ac438648135336c9791881ddadb
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NT5C3A SPTB ITGA6 ABCB4 MED12L PKD1L3 P2RX1

1.30e-051722007875ea290840e835952623b905eb610f3c71456d2
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NT5C3A SPTB ITGA6 ABCB4 MED12L PKD1L3 P2RX1

1.30e-051722007bcc50bed47465daa953ba91f17d1ee4c947ab461
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 SNRK MAST4 NID1 SEMA6A FLT1 MSRB3

1.30e-051722007a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

CAPN13 CA1 CDON PGLYRP4 CP NBEA CNTN3

1.40e-0517420077d2f802f493f19a068e097b2909a9000e2160266
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 SNRK MAST4 NID1 SEMA6A FLT1 MSRB3

1.51e-0517620073494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 SNRK MAST4 NID1 SEMA6A FLT1 MSRB3

1.51e-051762007d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CAPN13 MAST4 LIPH CFAP221 DPP10 CP NBEA

1.51e-0517620073bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH1 NAV3 NID1 C3 CNTFR LAMA2 VCAN

1.56e-0517720079ec7f1e64312d26d434b3312b58386715dbad644
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID1 TNFSF15 CDON TNC LAMA2 NBEA VCAN

1.56e-051772007bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH1 NAV3 NID1 C3 CNTFR LAMA2 VCAN

1.56e-051772007016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

CYP2B6 CAPN13 MAST4 LIPH CA1 CP CNTN3

1.62e-05178200735a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 UPK2 TNC CP GSTM2 TENM3 CNTN3

1.74e-05180200735c73670da90cb6924e822a2426d13a675685f09
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BLNK CYP46A1 NME8 RFTN1 MSRB3 P2RX1 PLXNA4

1.74e-051802007144818e69613296cde43f29cb8c20899c670b319
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF280D PERP DNAH6 LAMA2 CD8B P2RX1 LMO7

1.81e-05181200741969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NID1 CNTFR HTR2B TNC LAMA2 VCAN

1.81e-051812007c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF280D PERP DNAH6 LAMA2 CD8B P2RX1 LMO7

1.81e-0518120073f50e61dc2a52d71a5801584617607e6246adcf2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NID1 CNTFR HTR2B TNC LAMA2 VCAN

1.81e-051812007c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PERP SQOR POF1B LIPH CA1 CUBN P2RX1

1.81e-051812007bec917f6f56ae252639a5a76024be5df5c70a6d5
ToppCell11.5-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

BLNK RTN1 NME8 SIRPG KYNU BTLA SIGLEC6

1.81e-051812007193ee02f547a218b2fc13e1174ea4cff4f8a3450
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CYP2B6 FREM2 MAST4 CDON CP LMO7 RP1

1.81e-051812007c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPTBN1 LINC01558 NAV3 NID1 SEMA6A PKHD1L1 TENM3

1.94e-0518320074d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PERP ITGA6 FAT1 COL4A6 DPP10 TNC FAM83H

1.94e-051832007bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP1B1 ZNF280D C3 MAPK8IP1 MARVELD1 LAMA2 PLXNA4

1.94e-051832007269afec240a756eec3bbae5f30ec784281af3433
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIN4 NID1 LOXL3 CNTFR MAPK8IP1 SEPTIN5 VCAN

2.01e-051842007d754c3de621429b220ae4ac426cdfc619e848462
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CYP2B6 FAT1 MAST4 LIPH CFAP221 CP LMO7

2.08e-051852007673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 FAT1 MAST4 LIPH CA1 LMO7 RP1

2.08e-05185200798b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c5-WDR74|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYP1B1 C15orf39 RUSC2 FLT1 ZBTB47 P2RX1 VCAN

2.08e-05185200768edb1bb03ed221d49e583123ca4de14252d7bc5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 FAT1 SIPA1L2 MAML3 COL4A6 MSRB3 TENM3

2.08e-0518520078816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BLNK NME8 KCTD19 MSRB3 P2RX1 SIGLEC6 PLXNA4

2.08e-051852007c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BLNK NME8 KCTD19 MSRB3 P2RX1 SIGLEC6 PLXNA4

2.08e-051852007f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 FAT1 SIPA1L2 MAML3 COL4A6 MSRB3 TENM3

2.08e-05185200734fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BLNK NME8 KCTD19 MSRB3 P2RX1 SIGLEC6 PLXNA4

2.08e-0518520073cb816fc9541c04b4436e21d984216cfbbacff98
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP ADARB1 HNRNPL UBE2D3 PVR CP JMJD1C

2.08e-051852007eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CYP2B6 FREM2 MAST4 LIPH CFAP221 LMO7 RP1

2.15e-0518620072ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

PERP CAPN13 FAT1 MAST4 LIPH CP LMO7

2.15e-051862007d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NT5C3A SPTB POC1B MED12L CA1 COL4A6 PKHD1L1

2.15e-051862007e5014443e9d6e25943308483e20d48b776ae5373
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NT5C3A SPTB POC1B MED12L CA1 COL4A6 PKHD1L1

2.15e-051862007affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCellLPS_only-Hematopoietic_Meg-Ery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NT5C3A SPTB POC1B MED12L CA1 COL4A6 PKHD1L1

2.15e-05186200740d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 C15orf39 NAV3 SEMA6A HTR2B CP NBEA

2.15e-0518620070de87109da9324c597fadf2eb782f0f158afe832
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 C15orf39 NAV3 SEMA6A HTR2B CP NBEA

2.15e-051862007f23f21781a758541f59c06efa7739d26a03fb478
Diseasegamma-glutamylmethionine measurement

ASTN2 MAML3 CACNA1B

1.01e-0571973EFO_0021141
DiseaseDisorder of eye

CYP1B1 MAK FREM2 CC2D2A USH2A BBS5 WDPCP VCAN RP1

1.37e-052121979C0015397
Diseasegastroesophageal reflux disease

SNRK ADARB1 NAV3 MAML3 APOB VCAN

6.14e-051011976EFO_0003948
Diseasesubiculum volume

SPTBN1 ASTN2 MSRB3 VCAN

1.94e-04431974EFO_0009399
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN1

2.64e-0441972DOID:0050882 (implicated_via_orthology)
Diseasecholesteryl esters to total lipids in IDL percentage

GCKR CERS2 APOB JMJD1C

3.49e-04501974EFO_0022247
Diseasegamma-glutamylglutamine measurement

UBE2D3 ASTN2 MAML3

4.11e-04221973EFO_0021138
Diseasephospholipids in medium HDL measurement

GCKR CERS2 APOB GSTM2

5.04e-04551974EFO_0022295
Diseasetotal lipids in medium HDL measurement

GCKR CERS2 APOB GSTM2

6.17e-04581974EFO_0022310
Diseasefree cholesterol in medium HDL measurement

GCKR CERS2 APOB GSTM2

6.17e-04581974EFO_0022267
Diseasemilk allergy measurement, parental genotype effect measurement

MGRN1 RNASE11

6.54e-0461972EFO_0005939, EFO_0007019
Diseasebrain edema (implicated_via_orthology)

ABCC8 CP

6.54e-0461972DOID:4724 (implicated_via_orthology)
Diseasecholesterol in medium HDL measurement

GCKR CERS2 APOB GSTM2

6.58e-04591974EFO_0021903
Diseaseepilepsy (implicated_via_orthology)

GAD2 ITGA6 KCNH1 CACNA1B COX7A2P2 DEPDC5

8.18e-041631976DOID:1826 (implicated_via_orthology)
Diseaseneuroimaging measurement

SAMD9 NBEAL1 SPTBN1 ACTN4 MAPK8IP3 TYK2 NEO1 MAST4 NAV3 CC2D2A C2orf76 COX7A2P2 LAMA2 JMJD1C MSRB3 VCAN NIPAL2

8.76e-04106919717EFO_0004346
Diseasechronic mucus hypersecretion

USH2A MAML3

9.11e-0471972EFO_0005673
Diseasebeta-citrylglutamate measurement

HTR3D JMJD1C

9.11e-0471972EFO_0800060
DiseaseLDL cholesterol change measurement

APOB PKD1L3

9.11e-0471972EFO_0007804
Diseasecoronary artery disease, factor VII measurement

NBEAL1 GCKR FCHO1 FLT1 APOB

9.12e-041111975EFO_0001645, EFO_0004619
Diseasefactor VIII measurement, coronary artery disease

NBEAL1 FCHO1 FLT1 APOB RP1

9.88e-041131975EFO_0001645, EFO_0004630
Diseasecholesteryl esters to total lipids in large LDL percentage

GCKR APOB JMJD1C

1.15e-03311973EFO_0022249
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

GCKR MAML3 APOB TEAD4

1.19e-03691974EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Diseasegranule cell layer dentate gyrus volume

ASTN2 MSRB3

1.21e-0381972EFO_0009403
Diseasetissue plasminogen activator measurement, coronary artery disease

NBEAL1 FCHO1 FLT1 APOB

1.32e-03711974EFO_0001645, EFO_0004791
Diseasemean platelet volume

SPTBN1 ITGA6 ACTN4 GCKR SIRPG DCANP1 MAST4 PI4KA PVR NID1 HTR3D KYNU JMJD1C GSTM2 RSBN1 P2RX1

1.43e-03102019716EFO_0004584
Diseasemelanoma

CYP1B1 BRCA2 FLT1 TNC UBR4 CP CUBN

1.45e-032481977C0025202
Diseasehippocampus molecular layer volume

ASTN2 MSRB3 VCAN

1.64e-03351973EFO_0009397
Diseasetotal lipids in small HDL measurement

GCKR CERS2 GSTM2

1.64e-03351973EFO_0022311
Diseaseapolipoprotein B measurement

GCKR ZNF235 ABCB4 YIPF2 BRCA2 FIG4 PVR VASP APOB PKD1L3 GSTM2 RP1

1.76e-0366319712EFO_0004615
Diseasecholesterol in small HDL measurement

GCKR CERS2 GSTM2

1.78e-03361973EFO_0022226
Diseaselevel of Triacylglycerol (51:3) in blood serum

GCKR APOB

1.93e-03101972OBA_2045163
DiseaseGlobal developmental delay

MAPK8IP3 ALKBH8 TET3 CACNA1B NBEA

2.03e-031331975C0557874
Diseasephospholipids in small HDL measurement

GCKR CERS2 GSTM2

2.08e-03381973EFO_0022296
Diseasedentate gyrus volume measurement

MAST4 ASTN2 MSRB3

2.24e-03391973EFO_0010083
DiseaseNeurodegenerative Disorders

KYNU SEPTIN5 GSTM2

2.24e-03391973C0524851
DiseaseDegenerative Diseases, Central Nervous System

KYNU SEPTIN5 GSTM2

2.24e-03391973C0270715
Diseasedegree of unsaturation measurement

GCKR APOB JMJD1C

2.24e-03391973EFO_0022261
DiseaseDegenerative Diseases, Spinal Cord

KYNU SEPTIN5 GSTM2

2.24e-03391973C0751733
Diseasefunctional brain measurement

POC1B CC2D2A MSRB3 VCAN

2.25e-03821974EFO_0007849
Diseaselevel of Diacylglycerol (18:1_18:1) in blood serum

GCKR APOB

2.34e-03111972OBA_2045170
Diseasehippocampal amigdala transition area volume

ASTN2 MSRB3

2.34e-03111972EFO_0009401
Diseasehippocampal CA4 volume

MAST4 ASTN2 MSRB3

2.59e-03411973EFO_0009396
Diseasequality of life during menstruation measurement, decreased attention

TRIM36 MAML3

2.80e-03121972EFO_0009366, NCIT_C117245
DiseaseColorectal Carcinoma

CYP1B1 CHD1 ABCB4 FAT1 ABCC8 NID1 FAM110B COL4A6 APOB CUBN RHEB LMO7

2.81e-0370219712C0009402
Diseasemean reticulocyte volume

SAMD9 NT5C3A SPTB C15orf39 CHD1 GCKR ABCB4 CEP350 CC2D2A CA1 EP400 JMJD1C RESF1

2.90e-0379919713EFO_0010701
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

BLNK SNRK POC1B SIPA1L2 USH2A TET3 MAML3 COX7A2P2 LAMA2 NBEA WDPCP PLXNA4 CNTN3

2.96e-0380119713EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseBrittle diabetes

TYK2 ABCC8 CP

3.17e-03441973C0342302
DiseaseDiabetes Mellitus, Sudden-Onset

TYK2 ABCC8 CP

3.17e-03441973C4554117
DiseaseDiabetes, Autoimmune

TYK2 ABCC8 CP

3.17e-03441973C0205734
DiseaseDiabetes Mellitus, Ketosis-Prone

TYK2 ABCC8 CP

3.17e-03441973C3837958
DiseaseGranulomatosis with Polyangiitis

SEMA6A TENM3

3.30e-03131972EFO_0005297
Diseaseobesity (implicated_via_orthology)

ADARB1 TYK2 MED12L C3 GSTM2 ZFHX2

3.32e-032151976DOID:9970 (implicated_via_orthology)
DiseaseDiabetes Mellitus, Insulin-Dependent

TYK2 ABCC8 CP

3.38e-03451973C0011854
Diseasecholesterol to total lipids in large VLDL percentage

GCKR APOB JMJD1C

3.38e-03451973EFO_0022236
Diseasecortical thickness

NBEAL1 SPTBN1 ACTN4 MAPK8IP3 NEO1 MAST4 PI4KA NAV3 ASTN2 TRIM36 COX7A2P2 LAMA2 FSD2 JMJD1C VPS13D VCAN

3.39e-03111319716EFO_0004840
Diseaseeye morphology measurement

ABCB4 NAV3 ASTN2 FAM110B GSTM2 RP1

3.55e-032181976EFO_0007858
DiseaseSeizures

GAD2 ALKBH8 MED12L TET3 CACNA1B NBEA

3.55e-032181976C0036572
Diseasetriacylglycerol 54:4 measurement

ITGA6 GCKR APOB

3.60e-03461973EFO_0010422
Diseaseautism spectrum disorder (implicated_via_orthology)

ZNF280D CHD1 HTR2B NBEA EIF4E

3.61e-031521975DOID:0060041 (implicated_via_orthology)
Diseasevascular dementia (biomarker_via_orthology)

FLT1 EIF4E

3.83e-03141972DOID:8725 (biomarker_via_orthology)
Diseasecolonic neoplasm, overall survival

DPP10 IDS

3.83e-03141972EFO_0000638, EFO_0004288
DiseasePrimary biliary cirrhosis

ABCB4 TYK2 TNFSF15

3.83e-03471973C0008312
Diseasefrontal fibrosing alopecia

CYP1B1 NDUFA12 CNTN3

4.06e-03481973EFO_0009855
Diseasehippocampal CA1 volume

ASTN2 MSRB3 VCAN

4.06e-03481973EFO_0009394
Diseasecholesteryl esters to total lipids in small VLDL percentage

GCKR APOB JMJD1C

4.31e-03491973EFO_0022256
Diseaseemployment status

SQOR PLXNA4

4.40e-03151972EFO_0005241
DiseaseMeckel-Gruber syndrome

CC2D2A WDPCP

4.40e-03151972C0265215
Diseaseliver volume

GCKR JMJD1C

4.40e-03151972EFO_0600048
Diseasetriacylglycerol 52:3 measurement

GCKR APOB

4.40e-03151972EFO_0010415
DiseaseHypertriglyceridemia

GCKR APOB

4.40e-03151972C0020557
Diseasecognitive inhibition measurement

TRPM6 USH2A MSRB3

4.56e-03501973EFO_0007969
Diseasetriglycerides to total lipids in medium LDL percentage

GCKR APOB JMJD1C

4.56e-03501973EFO_0022334
Diseasepolyunsaturated fatty acids to total fatty acids percentage

GCKR APOB JMJD1C

4.56e-03501973EFO_0022303
DiseaseAdenoid Cystic Carcinoma

FAT1 MAML3 JMJD1C VCAN

4.59e-031001974C0010606
Diseasetriglycerides to total lipids in large LDL percentage

GCKR APOB JMJD1C

4.82e-03511973EFO_0022331
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

GCKR APOB JMJD1C

4.82e-03511973EFO_0022302
DiseaseIntrahepatic cholestasis of pregnancy

GCKR ABCB4

5.00e-03161972EFO_0009048
DiseasePre-Eclampsia

FLT1 CP

5.00e-03161972C0032914
Diseasemyopia (is_implicated_in)

LOXL3 LAMA2

5.00e-03161972DOID:11830 (is_implicated_in)
DiseaseAlpha ketoglutarate measurement

SAMD9 TENM3

5.00e-03161972EFO_0010457
Diseasesickle cell anemia (is_implicated_in)

C3 APOB

5.00e-03161972DOID:10923 (is_implicated_in)
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

GCKR CERS2 APOB JMJD1C

5.09e-031031974EFO_0008595, EFO_0020944
DiseaseDisease Exacerbation

DDB1 HNRNPL ABCB4 PRDX3 FLT1

5.11e-031651975C0235874
Diseasetriglycerides to total lipids in very large VLDL percentage

GCKR APOB JMJD1C

5.37e-03531973EFO_0022340
Diseaseresponse to cisplatin, platinum measurement

ADARB1 INTS7 TENM3

5.37e-03531973EFO_0010154, GO_0072718
Diseasefree cholesterol to total lipids in small LDL percentage

GCKR APOB JMJD1C

5.37e-03531973EFO_0022286
Diseasecholesteryl esters to total lipids in very large VLDL percentage

GCKR APOB JMJD1C

5.37e-03531973EFO_0022258
Diseaseplatelet measurement

ACTN4 GCKR SIRPG MED12L SEPTIN5 JMJD1C P2RX1

5.42e-033151977EFO_0005036
Diseaselipoprotein measurement

GCKR CERS2 APOB GSTM2

5.45e-031051974EFO_0004732
DiseaseBardet-Biedl syndrome 1 (disorder)

BBS5 WDPCP

5.65e-03171972C2936862
DiseaseKuhnt-Junius degeneration (is_implicated_in)

C3 FLT1

5.65e-03171972DOID:10873 (is_implicated_in)
Diseasecholesterol to total lipids in very large VLDL percentage

GCKR APOB JMJD1C

5.66e-03541973EFO_0022244
Diseasegallstones

GCKR ABCB4 POC1B JMJD1C

6.02e-031081974EFO_0004210
Diseasephosphatidylethanolamine measurement

GCKR USH2A COX7A2P2 APOB CNTN3

6.23e-031731975EFO_0010228
Diseasetriglycerides in large VLDL measurement

GCKR APOB JMJD1C

6.27e-03561973EFO_0022178
Diseasetriglycerides in very large VLDL measurement

GCKR APOB JMJD1C

6.27e-03561973EFO_0022325
Diseasetriglycerides in chylomicrons and extremely large VLDL measurement

GCKR APOB JMJD1C

6.27e-03561973EFO_0022316
Diseasefree cholesterol to total lipids in large HDL percentage

GCKR APOB GSTM2

6.27e-03561973EFO_0022279
Diseasecholesteryl esters to total lipids in large VLDL percentage

GCKR APOB JMJD1C

6.27e-03561973EFO_0022250
Diseaseglucose homeostasis measurement, acute insulin response measurement

ASTN2 MICU3

6.32e-03181972EFO_0006831, EFO_0006896

Protein segments in the cluster

PeptideGeneStartEntry
ALKGQEFAPSHQQVY

TNFSF15

71

O95150
GITAAFKPTSQHYTN

ZNF280D

81

Q6N043
QAGVYHPNVKVVSNF

NT5C3A

216

Q9H0P0
NPKHASVLAESGINY

EP400

2491

Q96L91
VSPGNSHLALYQVFK

DCANP1

146

Q8TF63
VSSGVNPLVYTLFNK

HTR2B

371

P41595
NSLHKVYSASPIFGV

BBS5

251

Q8N3I7
VGYTLVKHSQSEQVP

COL4A6

1466

Q14031
VTQHTSFRGYIIPKD

CYP2B6

371

P20813
DVTTTPSVQYINGKH

VCAN

1401

P13611
PSVQYINGKHLVTTV

VCAN

1406

P13611
NKPGIVYASLNHSVI

BTLA

251

Q7Z6A9
SKLPVHVNRTSFYSQ

ALKBH8

576

Q96BT7
LHPVDATSYGKQTNV

APOF

31

Q13790
VPAHKYVLAVGSSVF

BTBD6

151

Q96KE9
TQQFLSGHLPKYEQV

GSDMC

286

Q9BYG8
NHIKLSGSNPYTTVT

ACTN4

601

O43707
PGSTVLYRIFTVNHK

C3

141

P01024
VHYQHVFQKVQTSPG

CAPN13

571

Q6MZZ7
VKFFGPLSSNTLHQV

AQR

366

O60306
HAPQNIVRYSFKEGT

DNAI1

76

Q9UI46
AVHYTQVGNLIPKDS

DNAI1

101

Q9UI46
QSFSHYSIVGQKLGV

ELP6

56

Q0PNE2
HGSVSYNSNPVVFKE

FLG

3996

P20930
KAAVHTYGIASVPNQ

DDX20

456

Q9UHI6
FKPVVYHGVNLDQTV

C2orf76

21

Q3KRA6
ITYKTANSSPIHFAG

CACNA1B

2201

Q00975
GKTIQTISFLNYLFH

CHD1

511

O14646
NATLEHFYLTSGKQP

CERS2

81

Q96G23
HFYLTSGKQPKQVEV

CERS2

86

Q96G23
YQLAVASFPNKGVTS

COX7A2P2

71

O60397
TIKLYVVNLYGPTHT

DPP10

291

Q8N608
QPAIGTKVSDYILQH

ASTN2

1091

O75129
TPHSEIIFYKNGVNQ

ASH2L

536

Q9UBL3
GNIVSPSEIQAHLKY

CPT2

261

P23786
ASKPFQILYGHTNEV

NBEAL1

2481

Q6ZS30
LKFVGVIPQYHSSVN

RFTN1

156

Q14699
TIAIKHYFSIVPGNV

INTS7

321

Q9NVH2
VYSPQQIIKVYVGSH

KCTD19

391

Q17RG1
TNHKFNVTGTPEQYV

NDUFA12

111

Q9UI09
IRVTFHNKGAYPLSI

CP

461

P00450
QSPHSNLFGVQVQYK

ORC4

31

O43929
AENKPQYIHVTGTVF

DEPDC5

1496

O75140
FEVLYHSVKQGPIST

FCHO1

16

O14526
QFSSVKVIHVTSPQF

FAT1

346

Q14517
HLKTATVNFITSYPG

NOL9

226

Q5SY16
IKTGHPRYFNQLSTG

GAD2

171

Q05329
HSPKQDNIISVFYTI

OR2AG2

266

A6NM03
FTHYDILTPNGTKVA

LOXL3

616

P58215
NIVINPSKIGAYFSS

MED12L

61

Q86YW9
VNPNGHTYTFIDKVD

MAGEB2

171

O15479
VNIHYKSPTTAGFSQ

MAPK8IP3

596

Q9UPT6
ILTYGNTKPLTHFNA

MAML3

596

Q96JK9
YELVATPHNTSKGFQ

MEPCE

661

Q7L2J0
HANGNKLSSVVPSVY

GPBP1L1

221

Q9HC44
VTFQVGNRLFPAHKY

IBTK

566

Q9P2D0
QFRVKFLGSVQVPYH

MAPK8IP1

566

Q9UQF2
VHYKRGVSQQFSLPS

MGRN1

161

O60291
KHSVPQSLPQSNYFT

JMJD1C

1081

Q15652
SVEYHSLVSQGKPQS

FREM2

3031

Q5SZK8
PKIVIGYQSHADTAT

EIF4E

191

P06730
HYQVPDGSVVALVSK

PLXNA4

1586

Q9HCM2
VKYTQTFTLHANPAV

PERP

131

Q96FX8
AVQKGHLSSSYVQPL

PGLYRP4

176

Q96LB8
AFQPHKQTRLYGITT

NID1

1186

P14543
AAGKYHFSNLVSPTN

NAV3

1471

Q8IVL0
KVGLYTIYVNPANTH

DCAF8

331

Q5TAQ9
PSDVFKQYSHLTGTQ

GANC

341

Q8TET4
PYLIDGTHKITQSNA

GSTM2

61

P28161
HPLTAQYGVKVLRSF

PI4KA

1631

P42356
KHSFYPIPEQTLQAT

KCNH1

911

O95259
GLETVYEKFHPSIQS

MUL1

151

Q969V5
FVRKTGVFHANPYVL

LMO7

516

Q8WWI1
QSPSIKNGIEYHYVT

LAMA2

111

P24043
EPTTFQKYHQVSLLA

LIPH

366

Q8WWY8
AVYVATGLKFSPHLV

MICU3

461

Q86XE3
VFIYHGSANGINTKP

ITGA6

446

P23229
YVGHKDVVTSVQFSP

POC1B

56

Q8TC44
TQYPHAVGKNTLLIA

DDOST

231

P39656
LKENVQFHLYISTSP

ADARB1

436

P78563
YLGHTAKNAVITVPA

HSPA9

181

P38646
ITYQPSVSGEHKAQV

PIP5K1A

481

Q99755
SHFFPGNNVIYEKTI

POF1B

156

Q8WVV4
PYRNSVQKAHIYGIT

ABCB4

926

P21439
VQKAHIYGITFSISQ

ABCB4

931

P21439
RAHQVTYSQSPKIAT

GCKR

301

Q14397
NTFTKLITVNGQEYH

RHEB

41

Q15382
RSSQTTHGLYKVQPF

PGBD5

221

Q8N414
DSQRQQKHYGITSPI

PAPOLG

11

Q9BWT3
SPTHVGFKAKYSIAQ

CUBN

2321

O60494
FGTKQPYQVFTVEHS

WDPCP

291

O95876
HLRVSTAFVYTKNPN

APOB

3701

P04114
LHGNSVLQQTPAYIK

CD8B2

16

A6NJW9
EQVKYSVPDTGLFQH

LINC01558

36

Q9Y6Z2
DYHKVQSSGSFINTP

DNAH6

396

Q9C0G6
GHDSKQPYTLVVFFN

BLNK

376

Q8WV28
VKPLIDAVYSTGVHN

CC2D2A

1571

Q9P2K1
SLKFHNPDVYTLVTG

CARD14

91

Q9BXL6
PEHLISQKGFSYNVV

BRCA2

2036

P51587
YGPVVRVNVFHKTSV

CYP46A1

71

Q9Y6A2
KQLRAHGISSYFPVQ

DDX51

211

Q8N8A6
SIYSRFVQLGQSQHK

FIG4

816

Q92562
SYNPATAKEIINVGH

CA1

51

P00915
LHGNSVLQQTPAYIK

CD8B

16

P10966
HISYVANYPNGKVTQ

FRRS1

16

Q6ZNA5
EPGSTYKFRVIAINH

CDON

786

Q4KMG0
YIPNTFNVTVLHGSK

CNTFR

136

P26992
LPSGHSKQTQYVLDV

CADM4

206

Q8NFZ8
SPHSVINIFTKSYQL

CEP350

1061

Q5VT06
PSTQQHLKKVYASFA

TMBIM6

21

P55061
SQALKHPYFQVGQVL

MAK

276

P20794
TSKYQGPVHFALFVS

MARVELD1

51

Q9BSK0
PIVIHSSGKNYGFTI

MAST4

1141

O15021
RHSFAESLKVYPTQG

FAM110B

156

Q8TC76
GHPAFVNYSTSQKIS

HNRNPL

166

P14866
KNAFPVSGQLYTTHL

GBF1

561

Q92538
NTSVLGYHIPKDTVV

CYP1B1

406

Q16678
VHAGNFSTIPQYFKE

IDS

111

P22304
QVLHNESKGSPTSAY

FAM83H

861

Q6ZRV2
TTGKQFPRCQYHSVT

RNASE11

161

Q8TAA1
GSPIHTSVQFQASYL

CALCOCO1

76

Q9P1Z2
GKDNHSPVISYSIQA

CNTN3

621

Q9P232
PTVIYSSNHKLVFSN

DDB1

656

Q16531
VVVLNNSKFYHIGTT

FPGT

361

O14772
SLSPQQYQKGHTLAI

IFNE

66

Q86WN2
HTPGQDKFLAIFYTI

OR2AJ1

266

Q8NGZ0
SVTHSFISAGNKVYP

RP1

1866

P56715
VTIKFTPFQYGTAQI

CFAP221

221

Q4G0U5
QPKVGFYSSLNQTHT

FBXL21P

21

Q9UKT6
FIVTPKQTQGYCAEH

P2RX1

106

P51575
AVFHQTQGPSYSESK

PVR

76

P15151
HGLYNKVSQFPELTS

RUSC2

1086

Q8N2Y8
TYFTGILQKENGHVT

RTN1

121

Q16799
YFIPRNVIHQFKTVS

RSBN1

676

Q5VWQ0
LSQKVTHLIPFTNYS

USH2A

2776

O75445
FAHPKIGSNYSVKTV

SQOR

161

Q9Y6N5
TIKAQHEYVGPTTNF

TRIM36

191

Q9NQ86
DKQYVGFATLPNQVH

SEPTIN5

21

Q99719
PVLYSQSAIATGHQA

FNBP4

811

Q8N3X1
YGSQPLQSTQHITKH

RESF1

286

Q9HCM1
ANLHFPSVYVEQKTT

SAMD9

461

Q5K651
ATYNGPKHSLTQISQ

TAF1L

1476

Q8IZX4
KLYNTTTVVPVNHIF

NIPAL2

271

Q9H841
QIFAIHQLGPGYKST

NBEA

401

Q8NFP9
PATVHTIGSYFRLNK

FSD2

556

A1L4K1
PSLDNHQVSAKYIGS

CDC40

141

O60508
PSSHYVITLKAFNNV

NEO1

801

Q92859
VNTEVKANGPHLYSS

PHF12

541

Q96QT6
KEEGHPNTFTSYLQV

PKD1L3

256

Q7Z443
SKVYIVSHSSGQQVP

SIPA1L2

1366

Q9P2F8
YAPQKVAISIFQGNS

SIGLEC6

236

O43699
SVKLNIVISPYHFDN

SHPRH

96

Q149N8
NNHTLFGVLNYTKTP

MSH4

331

O15457
TQHAPYFKGTAVVNG

PRDX3

66

P30048
PLEHYLFTGNSSKTQ

SKIV2L

486

Q15477
KIIFHSGPTNSGKTY

SUPV3L1

201

Q8IYB8
PLQYHVTQEKGTESA

MSRB3

56

Q8IXL7
NTIISHYDGRQFPKV

NOP2

436

P46087
VKVLAESNPTHYGFL

PEX12

41

O00623
LIYNQKEGHFPRVTT

SIRPG

76

Q9P1W8
NQLYPGESFAHSIKT

PRORP

311

O15091
SQLHGSTKYIIDPQN

SNRK

656

Q9NRH2
KTAGYPNVNIHNFTT

SPTBN1

186

Q01082
PKTQFLGVYFVSSQE

ABCC8

336

Q09428
KAIGPVTNYSVATHV

HTR3D

51

Q70Z44
EYQIKTFSGQTHGFV

CMBL

201

Q96DG6
QPFLEKYQTIHSTGF

C15orf39

211

Q6ZRI6
VHTSYGPITVYFLNK

C15orf61

136

A6NNL5
FQVAYVVFQKPSGVS

RRP7A

116

Q9Y3A4
KISHTTGIPYNSQGQ

ERVK-25

726

P63136
KVAFTTRIYHPNINS

UBE2D2

66

P62837
PFIQHIYQKGTSTIS

ZNF596

86

Q8TC21
STLHSQFIRTAQPYK

TRPM6

561

Q9BX84
NDSHTPGTKVYEVVN

USP16

596

Q9Y5T5
TQSHGVKLTPAQYQG

ZFHX2

256

Q9C0A1
LSYILVVSQGSKHNP

NME8

221

Q8N427
TGIFIHQVVAKPSVY

SPIN4

216

Q56A73
LGHSYLVTSPVNQEK

SPATA31D1

1046

Q6ZQQ2
TKIAVDTAAGPYQNH

SEMA6A

421

Q9H2E6
PYQNHTVVFLGSEKG

SEMA6A

431

Q9H2E6
SPSTHYTAKIQALNG

TNC

1946

P24821
KVAFTTRIYHPNINS

UBE2D3

66

P61077
PSKDTTLIHQIFGGY

USP17L13

186

C9JLJ4
FYRLHFKIPQTNVSV

ACP5

136

P13686
YPVGKHAVQTTLESA

TENM3

1391

Q9P273
KTAGYPHVNVTNFTS

SPTB

186

P11277
GHFPCKVLSVNYTAI

PKHD1L1

1696

Q86WI1
QPSLTSVNGFHSKYA

TET3

1266

O43151
AGTSHDVKPFSQQTY

TEAD4

171

Q15561
TYNKHLFVHIGQSSP

TEAD4

241

Q15561
SVFPAHKGVLAAYSQ

ZBTB47

26

Q9UFB7
LSAYQVTNLVPGTKF

UPK2

101

O00526
SNTHISNSLFYPLGK

ZGRF1

756

Q86YA3
IPAVFQSPAHYKQTF

ZGRF1

1286

Q86YA3
GHSISKPNVISYLEQ

ZNF566

46

Q969W8
KISHTTGIPYNSQGQ

ERVK-19

731

Q9WJR5
LFIPQITTKHSGLYV

PSG2

286

P11465
PQRVKFTVTTGHYTI

TRAPPC10

801

P48553
KVAFTTKIYHPNINS

UBE2D4

66

Q9Y2X8
SPQFHKVTVAGISIY

YIPF2

156

Q9BWQ6
FTPANAVIGHYTLKI

TGM7

106

Q96PF1
GPSFKSVNTSVHIYD

FLT1

316

P17948
PRKQQGYSTVSHFNI

UBR4

4871

Q5T4S7
HEKDTSYSSGIPVQQ

ZNF235

296

Q14590
IADNPTFGIVLSKYH

TERB1

281

Q8NA31
FIKTYPAHQNRVSAI

WDFY1

106

Q8IWB7
TVHEKYQGQAPSVFS

TYK2

1171

P29597
IVRGVKYNQATPNFH

VASP

66

P50552
SAKQIFRQPGHTIYL

VPS13D

3166

Q5THJ4
YTGQHFNIPAITKAG

KYNU

226

Q16719