Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	presynapse	DMXL2 MYO6 GRIK4 ZZEF1 RAB6B PGR TRIM9 VAMP7 CNTNAP2 GPC4 CCL2 APPL1 RIMBP2 RAB6A VDAC1 VDAC2	5.90e-06	886	102	16	GO:0098793
Domain	EUKARYOTIC_PORIN	VDAC1 VDAC2	8.48e-05	3	100	2	PS00558
Domain	Porin_dom	VDAC1 VDAC2	2.81e-04	5	100	2	IPR023614
Domain	-	VDAC1 VDAC2	2.81e-04	5	100	2	2.40.160.10
Domain	Porin_Euk/Tom40	VDAC1 VDAC2	2.81e-04	5	100	2	IPR027246
Domain	Porin_3	VDAC1 VDAC2	2.81e-04	5	100	2	PF01459
Domain	Porin_Euk	VDAC1 VDAC2	2.81e-04	5	100	2	IPR001925
Domain	P-loop_NTPase	ABCC1 MYH8 MYO6 SMARCAD1 LRRK1 FANCM RAB6B DNAH14 ATAD3A ASPM KIF13A RAB6A	1.90e-03	848	100	12	IPR027417
Domain	-	OVCH1 ZZEF1 SCUBE1	2.72e-03	52	100	3	2.60.120.290
Domain	Bbox_C	TRIM24 TRIM9	2.85e-03	15	100	2	IPR003649
Domain	BBC	TRIM24 TRIM9	2.85e-03	15	100	2	SM00502
Domain	CUB_dom	OVCH1 ZZEF1 SCUBE1	3.53e-03	57	100	3	IPR000859
Domain	Myosin-like_IQ_dom	MYH8 ASPM	4.57e-03	19	100	2	IPR027401
Domain	-	MYH8 ASPM	4.57e-03	19	100	2	4.10.270.10
Domain	CH	EHBP1 LMO7 ASPM	5.12e-03	65	100	3	SM00033
Pubmed	Gelsolin segment 5 inhibits HIV-induced T-cell apoptosis via Vpr-binding to VDAC.	GSN VDAC1 VDAC2	1.01e-07	4	103	3	17254575
Pubmed	Human transcription factor protein interaction networks.	MRPS31 LHX4 NOP16 MYO6 RPS3A TRIM24 SDAD1 CCDC59 PBRM1 TRIM9 ATAD3A PRCC PES1 ARID5B OTUD4 ZNF107 VDAC1 VDAC2	2.00e-07	1429	103	18	35140242
Pubmed	Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity.	ARHGAP4 LMO7 ATAD3A OTUD4 VDAC1	4.81e-07	52	103	5	23182705
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EHBP1 DMXL2 MYO6 DGKD FANCM ESCO1 FAN1 ZNF610 ATAD3A APPL1	2.17e-06	493	103	10	15368895
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DMXL2 MYO6 RPS3A IGHV1-3 NDUFA9 PGM1 GSN USP31 LMO7 TRIM9 ATAD3A H1-0 OTUD4 RIMBP2 VDAC1 VDAC2	4.76e-06	1431	103	16	37142655
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CHAF1B MYO6 RPS3A LRRK1 NDUFA9 SDAD1 GSN PTP4A2 CCDC59 ATAD3A PES1 ASPM OTUD4 VDAC1 VDAC2	5.78e-06	1284	103	15	17353931
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FAT3 OVCH1 PBRM1 PES1 ASPM KDR KIF13A	6.53e-06	234	103	7	36243803
Pubmed	High-level expression, refolding and probing the natural fold of the human voltage-dependent anion channel isoforms I and II.	VDAC1 VDAC2	8.69e-06	2	103	2	17828567
Pubmed	Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC.	GSN VDAC1	8.69e-06	2	103	2	11039896
Pubmed	Subcellular localization of human voltage-dependent anion channel isoforms.	VDAC1 VDAC2	8.69e-06	2	103	2	7539795
Pubmed	Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation.	RAB6B RAB6A	8.69e-06	2	103	2	38830762
Pubmed	Heme oxygenase-1 transduction in endothelial cells causes downregulation of monocyte chemoattractant protein-1 and of genes involved in inflammation and growth.	HMOX1 CCL2	8.69e-06	2	103	2	16309586
Pubmed	Bisindolylpyrrole triggers transient mitochondrial permeability transitions to cause apoptosis in a VDAC1/2 and cyclophilin D-dependent manner via the ANT-associated pore.	VDAC1 VDAC2	8.69e-06	2	103	2	33046783
Pubmed	Induction of heme oxygenase-1 inhibits monocyte chemoattractant protein-1 mRNA expression in U937 cells.	HMOX1 CCL2	8.69e-06	2	103	2	16474202
Pubmed	Glomerular expression of monocyte chemoattractant protein-1 is predictive of poor renal prognosis in pediatric lupus nephritis.	PGM1 CCL2	8.69e-06	2	103	2	18495743
Pubmed	Ceramides bind VDAC2 to trigger mitochondrial apoptosis.	VDAC1 VDAC2	8.69e-06	2	103	2	31015432
Pubmed	Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase.	VDAC1 VDAC2	8.69e-06	2	103	2	38065946
Pubmed	MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: Pathophysiologic correlates.	HMOX1 CCL2	8.69e-06	2	103	2	16014038
Pubmed	VAMP7 knockdown in secretory granules impairs CCL2 secretion in mast cells.	VAMP7 CCL2	8.69e-06	2	103	2	38029541
Pubmed	PDGF-induced migration of vascular smooth muscle cells is inhibited by heme oxygenase-1 via VEGFR2 upregulation and subsequent assembly of inactive VEGFR2/PDGFRβ heterodimers.	HMOX1 KDR	8.69e-06	2	103	2	22426130
Pubmed	Macrophage inflammatory protein-1 delta: a novel osteoclast stimulating factor secreted by renal cell carcinoma bone metastasis.	MAPKAP1 CCL2	8.69e-06	2	103	2	18316587
Pubmed	IκBζ is a transcriptional key regulator of CCL2/MCP-1.	NFKBIZ CCL2	8.69e-06	2	103	2	23547114
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	RPS3A NDUFA9 CCDC59 ATAD3A PES1 H1-0 GPC4 RAB6A VDAC1 VDAC2	1.29e-05	604	103	10	37616343
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	NOP16 MYO6 SDAD1 GSN CCDC59 PBRM1 ATAD3A PES1 UTP3	1.41e-05	483	103	9	36912080
Pubmed	Comparative mapping between humans and pigs: localization of 58 anchorage markers (TOASTs) by use of porcine somatic cell and radiation hybrid panels.	HMOX1 GSN PGR CCL2	1.90e-05	53	103	4	11130978
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MYO6 RPS3A MBD3 GSN LMO7 TRIM9 ATAD3A PRCC ASPM	2.04e-05	506	103	9	30890647
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MYO6 COLGALT2 NDUFA9 TRIM24 MEPE CCDC59 PBRM1 ARID5B OTUD4 RAB6A	2.05e-05	638	103	10	31182584
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MRPS31 NOP16 MYO6 RPS3A NDUFA9 SDAD1 GSN LMO7 ATAD3A PES1 H1-0 UTP3 VDAC1 VDAC2	2.07e-05	1257	103	14	36526897
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	MRPS31 ABCC1 CHAF1B NOP16 GBE1 NDUFA9 SDAD1 GSN LMO7 ATAD3A PES1 H1-0 VAMP7 VDAC1 VDAC2	2.23e-05	1440	103	15	30833792
Pubmed	Evolutionarily conserved regulators of tau identify targets for new therapies.	HMOX1 RAB6B PSMA8 PTP4A2 SELENOK VAMP7 APPL1 RAB6A VDAC2	2.37e-05	516	103	9	36610398
Pubmed	A novel mouse mitochondrial voltage-dependent anion channel gene localizes to chromosome 8.	VDAC1 VDAC2	2.60e-05	3	103	2	8812436
Pubmed	Cardioprotection by N-acetylglucosamine linkage to cellular proteins.	VDAC1 VDAC2	2.60e-05	3	103	2	18285568
Pubmed	Rab6 family proteins interact with the dynein light chain protein DYNLRB1.	RAB6B RAB6A	2.60e-05	3	103	2	18044744
Pubmed	Revised fine mapping of the human voltage-dependent anion channel loci by radiation hybrid analysis.	VDAC1 VDAC2	2.60e-05	3	103	2	10501981
Pubmed	Parenteral iron formulations differentially affect MCP-1, HO-1, and NGAL gene expression and renal responses to injury.	HMOX1 CCL2	2.60e-05	3	103	2	20504881
Pubmed	Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria.	HMOX1 CCL2	2.60e-05	3	103	2	22964851
Pubmed	VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis.	MYO6 KDR	2.60e-05	3	103	2	20434959
Pubmed	Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure.	VDAC1 VDAC2	2.60e-05	3	103	2	35047503
Pubmed	A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6.	RAB6B RAB6A	2.60e-05	3	103	2	23737971
Pubmed	A maxi-chloride channel in the inner membrane of mammalian mitochondria.	VDAC1 VDAC2	2.60e-05	3	103	2	18805391
Pubmed	Sodium azide suppresses LPS-induced expression MCP-1 through regulating IκBζ and STAT1 activities in macrophages.	NFKBIZ CCL2	2.60e-05	3	103	2	28391993
Pubmed	Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth.	RAB6B RAB6A	2.60e-05	3	103	2	25492866
Pubmed	HIV-1 Tat protein stimulates in vivo vascular permeability and lymphomononuclear cell recruitment.	CCL2 KDR	2.60e-05	3	103	2	11145723
Pubmed	Expression of voltage-dependent anion channels in endometrial cancer and its potential prognostic significance.	VDAC1 VDAC2	2.60e-05	3	103	2	32829673
Pubmed	Genetic demonstration that the plasma membrane maxianion channel and voltage-dependent anion channels are unrelated proteins.	VDAC1 VDAC2	2.60e-05	3	103	2	16291750
Pubmed	IL-10/HMOX1 signaling modulates cochlear inflammation via negative regulation of MCP-1/CCL2 expression in cochlear fibrocytes.	HMOX1 CCL2	2.60e-05	3	103	2	25780042
Pubmed	The murine voltage-dependent anion channel gene family. Conserved structure and function.	VDAC1 VDAC2	2.60e-05	3	103	2	9228078
Pubmed	Role of cysteines in mammalian VDAC isoforms' function.	VDAC1 VDAC2	2.60e-05	3	103	2	26947058
Pubmed	The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.	MRPS31 NOP16 MAFA ATAD3A PES1 H1-0	5.13e-05	220	103	6	31822558
Pubmed	The association between inflammatory markers (iNOS, HO-1, IL-33, MIP-1β) and depression with and without posttraumatic stress disorder.	HMOX1 CCL2	5.19e-05	4	103	2	30296742
Pubmed	Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through β1-integrin and VEGFR2.	MAPKAP1 KDR	5.19e-05	4	103	2	23709605
Pubmed	Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway.	VDAC1 VDAC2	5.19e-05	4	103	2	15082785
Pubmed	Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation.	VDAC1 VDAC2	5.19e-05	4	103	2	25341036
Pubmed	Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma.	VDAC1 VDAC2	5.19e-05	4	103	2	31974380
Pubmed	Stromal Pbrm1 mediates chromatin remodeling necessary for embryo implantation in the mouse uterus.	PGR PBRM1	5.19e-05	4	103	2	38426493
Pubmed	Lipoxin A4 attenuates hyperoxia‑induced lung epithelial cell injury via the upregulation of heme oxygenase‑1 and inhibition of proinflammatory cytokines.	HMOX1 CCL2	5.19e-05	4	103	2	31746387
Pubmed	Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.	VDAC1 VDAC2	5.19e-05	4	103	2	8420959
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DMXL2 DOCK10 ZNF518A LMO7 TRIM9 APPL1	5.81e-05	225	103	6	12168954
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	MRPS31 NOP16 SDAD1 PES1 H1-0 VAMP7	6.26e-05	228	103	6	30471916
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MRPS31 NEXMIF ZZEF1 ESCO1 DNAH14 PGM1 TRIM9 ARID5B FBXO43 PSMG4	6.82e-05	736	103	10	29676528
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	RPS3A TRIM24 MBD3 PBRM1	7.50e-05	75	103	4	25593309
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CHAF1B NOP16 NFKBIZ MBD3 PBRM1 PES1 H1-0 CRISPLD1	8.00e-05	469	103	8	27634302
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MRPS31 MYO6 RPS3A SMARCAD1 CCDC38 MBD3 SDAD1 PBRM1 ATAD3A PES1 H1-0 UTP3 VDAC1 VDAC2	8.04e-05	1425	103	14	30948266
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	RPS3A MBD3 SDAD1 PBRM1 ATAD3A PES1 H1-0 VDAC1 VDAC2	8.08e-05	605	103	9	28977666
Pubmed	Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors.	ABCC1 KDR	8.64e-05	5	103	2	19924384
Pubmed	Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport.	RAB6B RAB6A	8.64e-05	5	103	2	11929610
Pubmed	ELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals.	RAB6B RAB6A	8.64e-05	5	103	2	32521280
Pubmed	Heme oxygenase-1 induction in macrophages by a hemoglobin-based oxygen carrier reduces endotoxin-stimulated cytokine secretion.	HMOX1 CCL2	8.64e-05	5	103	2	18665050
Pubmed	Characterising the dynamics of placental glycogen stores in the mouse.	GBE1 PGM1 KDR	8.72e-05	29	103	3	32798765
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	CHAF1B MYO6 RPS3A PSMA8 CCDC59 LMO7 ATAD3A PES1 VDAC2	1.02e-04	624	103	9	33729478
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	ABCC1 MYO6 NDUFA9 SELENOK ATAD3A PES1 VAMP7 GPC4 RAB6A VDAC1 VDAC2	1.12e-04	942	103	11	31073040
Pubmed	Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.	SDAD1 ARHGAP4 PBRM1 PES1 UTP3	1.14e-04	159	103	5	22751105
Pubmed	The layered structure of human mitochondrial DNA nucleoids.	ATAD3A VDAC1 VDAC2	1.18e-04	32	103	3	18063578
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MRPS31 MBD3 SDAD1 ATAD3A PES1 ARID5B UTP3 ZC3H7B	1.18e-04	496	103	8	31343991
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	ABCC1 MBD3 LMO7 VAMP7 CNTNAP2 RIMBP2 RAB6A	1.22e-04	371	103	7	15747579
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MRPS31 MAPKAP1 DMXL2 MYO6 RPS3A SMARCAD1 NDUFA9 TRIM24 USP31 CASKIN2 ATAD3A PRCC PES1 ASPM	1.26e-04	1487	103	14	33957083
Pubmed	Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death.	VDAC1 VDAC2	1.29e-04	6	103	2	17417626
Pubmed	Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract.	PGR PBRM1	1.29e-04	6	103	2	37714160
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MRPS31 MAPKAP1 NOP16 NDUFA9 RAB6B MBD3 SDAD1 CCDC59 PBRM1 PES1 OTUD4 UTP3 ZC3H7B VDAC2	1.35e-04	1497	103	14	31527615
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MAPKAP1 DMXL2 DOCK10 SMARCAD1 COLGALT2 ZZEF1 CASKIN2 PRCC ZC3H7B	1.39e-04	650	103	9	38777146
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MRPS31 MAPKAP1 EHBP1 DMXL2 NDUFA9 RAB6B TRIM9 ATAD3A H1-0 CNTNAP2 APPL1 VDAC1	1.42e-04	1139	103	12	36417873
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	CHAF1B RPS3A FANCM LMO7 ATAD3A PES1 H1-0 VDAC1 VDAC2	1.42e-04	652	103	9	31180492
Pubmed	Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex.	NOP16 LMO7 ATAD3A PES1 H1-0	1.44e-04	167	103	5	35833506
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	HMOX1 NDUFA9 ATAD3A VAMP7 RAB6A VDAC1 VDAC2	1.72e-04	392	103	7	33144569
Pubmed	Isolation, characterization, and mapping of two mouse mitochondrial voltage-dependent anion channel isoforms.	VDAC1 VDAC2	1.81e-04	7	103	2	8660977
Pubmed	Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.	NFKBIZ HMOX1	1.81e-04	7	103	2	29670287
Pubmed	Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms.	VDAC1 VDAC2	1.81e-04	7	103	2	7517385
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LRRK1 ZZEF1 ARHGAP4 LMO7 CASKIN2 TRIM9 CNTNAP2 ZC3H7B	1.83e-04	529	103	8	14621295
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	MRPS31 NOP16 RPS3A NDUFA9 SDAD1 GSN PES1 H1-0 OTUD4	1.90e-04	678	103	9	30209976
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NOP16 MYO6 PSMA8 MBD3 SDAD1 CCDC59 PBRM1 LMO7 PES1 OTUD4 RAB6A VDAC1 VDAC2	2.08e-04	1371	103	13	36244648
Pubmed	Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.	MYO6 GSN APPL1 VDAC1	2.20e-04	99	103	4	29676259
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	EHBP1 DMXL2 LMO7 CNTNAP2	2.29e-04	100	103	4	10048485
Pubmed	A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes.	VDAC1 VDAC2	2.40e-04	8	103	2	34799735
Pubmed	The Anti-Inflammatory Agent Bindarit Attenuates the Impairment of Neural Development through Suppression of Microglial Activation in a Neonatal Hydrocephalus Mouse Model.	HMOX1 CCL2	2.40e-04	8	103	2	34992132
Pubmed	FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.	ABCC1 CCL2	2.40e-04	8	103	2	15240672
Pubmed	TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.	VDAC1 VDAC2	2.40e-04	8	103	2	27641616
Pubmed	Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy.	VDAC1 VDAC2	2.40e-04	8	103	2	23060438
Pubmed	Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase.	VDAC1 VDAC2	2.40e-04	8	103	2	23068103
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	MRPS31 SMARCAD1 TRIM24 MBD3 FZD1 ARID5B KDR	2.76e-04	424	103	7	21731673
Pubmed	Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.	ABCC1 SMARCAD1 ATAD3A ZC3H7B	2.86e-04	106	103	4	33087821
Interaction	NAP1L1 interactions	NOP16 RPS3A LRRK1 SDAD1 PES1 H1-0 MTNR1A ASPM VDAC1 VDAC2	8.39e-06	345	100	10	int:NAP1L1
GeneFamily	Voltage dependent anion channels	VDAC1 VDAC2	4.55e-05	3	71	2	306
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH1 PGR SNED1 LMO7 TRIM9 CRISPLD1	2.28e-06	164	103	6	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO6 NFKBIZ DNAH14 RANBP17 LMO7 B4GALNT3	4.04e-06	181	103	6	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK4 SCUBE1 ASPM CCL2 B4GALNT3 CRISPLD1	4.17e-06	182	103	6	72e65a23cd36085bc880087d3cae92395de918a1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK4 SCUBE1 ASPM CCL2 B4GALNT3 CRISPLD1	4.17e-06	182	103	6	05c167158815bf25d509df59ab386e1990712765
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 NEXMIF NFKBIZ ZNF208 PTP4A2 ARID5B	5.66e-06	192	103	6	2510f22197502f60fd266b7f42eff040f25b8ae7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 NEXMIF NFKBIZ ZNF208 PTP4A2 ARID5B	5.66e-06	192	103	6	e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCell	(3)_Chondrocytes-(30)_Chondro\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	RPS3A LRRK1 GSN FZD1 GPC4 KDR	6.19e-06	195	103	6	f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RPS3A TRIM24 PGM1 ARID5B CNTNAP2 GPC4	6.95e-06	199	103	6	afed9fefd1355eb3bc17fbc7ce04daad890a0f9f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RPS3A TRIM24 PGM1 ARID5B CNTNAP2 GPC4	6.95e-06	199	103	6	3c9bd4d4b166788f807eaaf4f74735949031c295
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 PSMA8 FAN1 SCUBE1 PPP2R3A	2.76e-05	152	103	5	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 PSMA8 FAN1 SCUBE1 PPP2R3A	2.76e-05	152	103	5	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 FAT3 ALX4 CNTNAP2 RIMBP2	3.53e-05	160	103	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 FAT3 ALX4 CNTNAP2 RIMBP2	3.53e-05	160	103	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RANBP17 PPP2R3A GPC4 RIMBP2 CCDC40	3.97e-05	164	103	5	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK4 ASPM CCL2 B4GALNT3 CRISPLD1	5.26e-05	174	103	5	43c0e758fa8683708475aec846929ac70d41d7f5
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GBE1 GRIK4 DNAH14 SNED1 B4GALNT3	5.71e-05	177	103	5	921783ed0fe20294d2f384d9136924b679df01bb
ToppCell	10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GBE1 HMOX1 GSN H1-0 CRISPLD1	5.71e-05	177	103	5	f7a2e6b5e82f0565f8030696944f33c544233b94
ToppCell	10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GBE1 HMOX1 GSN H1-0 CRISPLD1	5.71e-05	177	103	5	ef02ee75db36a92dda889efb6fad1193efbc4be4
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TRIM24 DNAH14 PPP2R3A CRISPLD1 PRIMPOL	6.68e-05	183	103	5	1464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GBE1 GRIK4 DNAH14 SNED1 B4GALNT3	6.86e-05	184	103	5	9a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	MYO6 NEXMIF RANBP17 LMO7 B4GALNT3	7.04e-05	185	103	5	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NFKBIZ ZNF208 PPP2R3A RIMBP2 B4GALNT3	7.22e-05	186	103	5	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DNAAF9 FANCM ARID5B DENND6B UTP3	7.22e-05	186	103	5	bca5215d406f1785bf3a420201d5686071fcaca5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO6 NFKBIZ DNAH14 RANBP17 B4GALNT3	7.22e-05	186	103	5	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	COVID-19_Mild-Neu_4\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	ABCC1 H1-0 ASPM APPL1 ZC3H7B	7.40e-05	187	103	5	714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO6 DGKD RANBP17 LMO7 B4GALNT3	7.59e-05	188	103	5	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO6 FAT3 PGR FZD1 GPC4	7.59e-05	188	103	5	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO6 USP31 CASKIN2 KDR KIF13A	7.98e-05	190	103	5	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPKAP1 SMARCAD1 ESCO1 ZNF518A PTP4A2	8.18e-05	191	103	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NFKBIZ PPP2R3A ARID5B GPC4 RIMBP2	8.18e-05	191	103	5	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 DNAH14 PPP2R3A ARID5B CCL2	8.18e-05	191	103	5	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 DNAH14 PPP2R3A ARID5B CCL2	8.18e-05	191	103	5	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPKAP1 SMARCAD1 ESCO1 ZNF518A PTP4A2	8.18e-05	191	103	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	MYO6 DNAH14 RANBP17 LMO7 B4GALNT3	8.38e-05	192	103	5	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|(0)_Normal/No_Treatment / Stress and Cell class	FZD1 SNED1 LMO7 GPC4 CCL2	8.38e-05	192	103	5	7a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	NFKBIZ ZNF208 PPP2R3A RIMBP2 B4GALNT3	8.38e-05	192	103	5	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	MYO6 DNAH14 RANBP17 LMO7 B4GALNT3	8.38e-05	192	103	5	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO6 USP31 CASKIN2 KDR KIF13A	8.59e-05	193	103	5	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	RPS3A LRRK1 HMOX1 FZD1 CCL2	8.80e-05	194	103	5	11ff53a748160570d2908ea9eb9779c038e5b676
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GRIK4 MEPE FZD1 SNED1 ARID5B	9.01e-05	195	103	5	c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 DNAAF9 DNAH14 PPP2R3A LMO7	9.01e-05	195	103	5	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT3 DOCK10 GRIK4 ARID5B CNTNAP2	9.46e-05	197	103	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPKAP1 TMEM67 ARID5B CNTNAP2 CCL2	9.46e-05	197	103	5	9af431323da6d099459b7360af40e5df998cffbd
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT3 DOCK10 FZD1 SNED1 CNTNAP2	9.46e-05	197	103	5	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT3 DOCK10 GRIK4 ARID5B CNTNAP2	9.46e-05	197	103	5	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPKAP1 TMEM67 ARID5B CNTNAP2 CCL2	9.69e-05	198	103	5	a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO6 DGKD DNAH14 RANBP17 LMO7	9.92e-05	199	103	5	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	COVID-19_Severe-PLT_5\|COVID-19_Severe / Disease Group and Platelet Clusters	RPS3A RAB6B ARHGAP4 NXF3 DENND6B	9.92e-05	199	103	5	93e814f45b220687007c75f20ec1ea25234f7d65
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	RPS3A FAT3 NFKBIZ ARID5B GPC4	9.92e-05	199	103	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FZD1 SNED1 ARID5B GPC4 CCL2	9.92e-05	199	103	5	a697b3f0760e66bad8ea8d83cf6fea5934692c56
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NEXMIF RAB6B PGR RAB6A VDAC1	9.92e-05	199	103	5	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 DOCK10 GSN KIF13A RAB6A	1.02e-04	200	103	5	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-3\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	LHX4 PSMA8 MTNR1A FGF19	1.20e-04	109	103	4	5d194bf95eb777fb4d01bbe5b1639f17ea1bc11a
Disease	retinal degeneration (implicated_via_orthology)	RAB6B RAB6A VDAC1 VDAC2	5.10e-06	33	102	4	DOID:8466 (implicated_via_orthology)
Disease	Nodular glomerulosclerosis	CCL2 KDR VDAC1 VDAC2	1.24e-05	41	102	4	C0017667
Disease	Diabetic Nephropathy	CCL2 KDR VDAC1 VDAC2	1.64e-05	44	102	4	C0011881
Disease	myocardial infarction (implicated_via_orthology)	HMOX1 CCL2 KDR VDAC2	8.23e-05	66	102	4	DOID:5844 (implicated_via_orthology)
Disease	Epilepsy, Cryptogenic	NEXMIF CNTNAP2 VDAC1 VDAC2	1.91e-04	82	102	4	C0086237
Disease	Awakening Epilepsy	NEXMIF CNTNAP2 VDAC1 VDAC2	1.91e-04	82	102	4	C0751111
Disease	Aura	NEXMIF CNTNAP2 VDAC1 VDAC2	1.91e-04	82	102	4	C0236018
Disease	visual epilepsy (implicated_via_orthology)	CNTNAP2 VDAC1 VDAC2	2.22e-04	34	102	3	DOID:11832 (implicated_via_orthology)
Disease	lung disease (biomarker_via_orthology)	HMOX1 GSN CCL2	2.42e-04	35	102	3	DOID:850 (biomarker_via_orthology)
Disease	Henoch-Schoenlein purpura (is_marker_for)	HMOX1 CCL2	2.46e-04	7	102	2	DOID:11123 (is_marker_for)
Disease	Fanconi anemia (implicated_via_orthology)	FANCM FAN1	3.27e-04	8	102	2	DOID:13636 (implicated_via_orthology)
Disease	colitis (biomarker_via_orthology)	HMOX1 CCL2 KDR	4.17e-04	42	102	3	DOID:0060180 (biomarker_via_orthology)
Disease	high grade glioma (is_marker_for)	CHAF1B ASPM KDR	4.17e-04	42	102	3	DOID:3070 (is_marker_for)
Disease	Tendinopathy	CHAF1B CNTNAP2	4.19e-04	9	102	2	EFO_1001434
Disease	Amyloidosis	HMOX1 GSN	5.23e-04	10	102	2	C0002726
Disease	Epilepsy	NEXMIF CNTNAP2 VDAC1 VDAC2	5.67e-04	109	102	4	C0014544
Disease	Internal Carotid Artery Diseases	HMOX1 CCL2	6.38e-04	11	102	2	C0750986
Disease	Arterial Diseases, Common Carotid	HMOX1 CCL2	6.38e-04	11	102	2	C0750987
Disease	Carotid Atherosclerosis	HMOX1 CCL2	6.38e-04	11	102	2	C0577631
Disease	External Carotid Artery Diseases	HMOX1 CCL2	6.38e-04	11	102	2	C0600178
Disease	Carotid Artery Diseases	HMOX1 CCL2	6.38e-04	11	102	2	C0007273
Disease	visual epilepsy (is_implicated_in)	CNTNAP2 ASPM	6.38e-04	11	102	2	DOID:11832 (is_implicated_in)
Disease	macular retinal edema (is_marker_for)	CCL2 KDR	7.64e-04	12	102	2	DOID:4449 (is_marker_for)
Disease	optic cup area measurement	FAT3 H1-0 CRISPLD1	9.73e-04	56	102	3	EFO_0006940
Disease	hepatic encephalopathy (biomarker_via_orthology)	HMOX1 CCL2	1.21e-03	15	102	2	DOID:13413 (biomarker_via_orthology)
Disease	endometriosis (biomarker_via_orthology)	PGR KDR	1.38e-03	16	102	2	DOID:289 (biomarker_via_orthology)
Disease	Liver Cirrhosis, Experimental	DOCK10 NFKBIZ HMOX1 SERPINA6 TRIM24 ATP10D GSN CCL2 APPL1	1.47e-03	774	102	9	C0023893
Disease	Glycogen storage disease	GBE1 PGM1	1.56e-03	17	102	2	cv:C0017919
Disease	Alzheimer disease, psychotic symptoms	CHAF1B RIMBP2	1.56e-03	17	102	2	EFO_0005940, MONDO_0004975
Disease	chemokine (C-C motif) ligand 27 measurement	SLCO1B7 USP31 PBRM1	1.86e-03	70	102	3	EFO_0008082
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	NFKBIZ FAN1	1.95e-03	19	102	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	NFKBIZ FAN1	1.95e-03	19	102	2	C2936783
Disease	Lung Injury	HMOX1 CCL2	2.38e-03	21	102	2	C0273115
Disease	Chronic Lung Injury	HMOX1 CCL2	2.38e-03	21	102	2	C2350344
Disease	Drug-Induced Liver Disease	ABCC1 HMOX1 SERPINA6 PGM1 GSN CCL2	2.83e-03	404	102	6	C0860207
Disease	Drug-Induced Acute Liver Injury	ABCC1 HMOX1 SERPINA6 PGM1 GSN CCL2	2.83e-03	404	102	6	C3658290
Disease	Hepatitis, Toxic	ABCC1 HMOX1 SERPINA6 PGM1 GSN CCL2	2.83e-03	404	102	6	C0019193
Disease	Chemically-Induced Liver Toxicity	ABCC1 HMOX1 SERPINA6 PGM1 GSN CCL2	2.83e-03	404	102	6	C4279912
Disease	Chemical and Drug Induced Liver Injury	ABCC1 HMOX1 SERPINA6 PGM1 GSN CCL2	2.83e-03	404	102	6	C4277682
Disease	Hepatitis, Drug-Induced	ABCC1 HMOX1 SERPINA6 PGM1 GSN CCL2	2.83e-03	404	102	6	C1262760
Disease	Nephritis, Interstitial	FAN1 CCL2	3.11e-03	24	102	2	C0027707
Disease	Drug toxicity	ABCC1 HMOX1 ARID5B	3.12e-03	84	102	3	C0013221
Disease	Adverse reaction to drug	ABCC1 HMOX1 ARID5B	3.12e-03	84	102	3	C0041755
Disease	neuroimaging measurement, brain volume measurement	FAT3 ESCO1 ALX4 C17orf58 PBRM1	3.20e-03	286	102	5	EFO_0004346, EFO_0006930
Disease	Myocardial Ischemia	HMOX1 PGM1 CCL2 KDR	3.30e-03	176	102	4	C0151744
Disease	interstitial lung disease (is_marker_for)	HMOX1 CCL2	3.37e-03	25	102	2	DOID:3082 (is_marker_for)
Disease	feeling nervous measurement	DNAH14 PBRM1 ZC3H7B	3.44e-03	87	102	3	EFO_0009597

Protein segments in the cluster

Peptide	Gene	Start	Entry
KSRVTQSNFAVGYKT	VDAC1	161	P21796
KGKKRRNRTTFTSYQ	ALX4	211	Q9H161
VFLKKLNQRSRGRYQ	B4GALNT3	676	Q6L9W6
IATRNTKKNRSLYRN	ATAD3A	381	Q9NVI7
NRAGSSRQSIQKYIK	H1-0	41	P07305
NVRRALNSKNYKTSS	C4orf47	291	A7E2U8
RVYSIQKKRVAFNVS	CHAF1B	196	Q13112
NARVTRLYFNSQGNK	DMXL2	2806	Q8TDJ6
FRQVKDSSVKRGYFQ	DENND6B	136	Q8NEG7
RGYNKRVKYQSVLQS	ASPM	1836	Q8IZT6
KFSGAYVNNRIRTTK	ATP10D	66	Q9P241
GLRKRVKVFQSSANY	PGM1	21	P36871
FRKTYVGDQLQRTSK	RANBP17	556	Q9H2T7
SNILRSGRSKQFYNQ	OTUD4	1031	Q01804
SAKAGYNVKQLFRRV	RAB6A	156	P20340
SAKTGYNVKQLFRRV	RAB6B	156	Q9NRW1
ISPYNRKGSFRKQDQ	NXF3	71	Q9H4D5
KTIAQRIQNGSYKSI	PBRM1	231	Q86U86
QFRELKNTVSYSGKR	NFKBIZ	151	Q9BYH8
KQKRRTLKNRGYAQS	MAFA	256	Q8NHW3
KGSSKSQNYFTNRQR	MEPE	81	Q9NQ76
TNRQRLNKEYSISNK	MEPE	91	Q9NQ76
KSRQRVRYDSSNQVK	MBD3	76	O95983
RNRKVTIYSFTGNQR	LRRK1	1056	Q38SD2
SEVRRLYVSKGFNKN	GPC4	31	O75487
SSYVKRFNRKREGQI	C17orf58	316	Q2M2W7
NLTRKAGYLNARNKT	APPL1	276	Q9UKG1
RIYNQSQSNKRSIYK	FANCM	596	Q8IYD8
GKTVNTKRVIQYFAT	MYH8	186	P13535
SSAKQRQLYKNRGFL	FGF19	146	O95750
KNLKRRSQFFEQGSS	LMO7	1191	Q8WWI1
QFYKSVKRSRGSSKQ	LHX4	226	Q969G2
NTKYSQKFQGRVTIT	IGHV1-3	76	A0A0C4DH29
NANIKSSSRYLRNKA	NDUFA9	171	Q16795
RVKRGSTFQNTYNLK	PPP2R3A	96	Q06190
TKLLGSTKRLNVNYQ	CASKIN2	31	Q8WXE0
KGVVSSSQRFYQLTK	PGR	861	P06401
NANRRRKFYITQLKT	FBXO43	541	Q4G163
RKFYTRLTNSKQGET	FZD1	631	Q9UP38
QRRYKQFSQILKNIG	GBE1	46	Q04446
ISNTRTYRVAVGKNN	CTRC	76	Q99895
TVNNTVTVRSFKKRY	DOCK10	196	Q96BY6
YNFTNRKISVQRLAS	CCL2	36	P13500
KHYFIKSNRNGIQTI	CRISPLD1	361	Q9H336
KSNRNGIQTIGKYQS	CRISPLD1	366	Q9H336
TSNKTTKYFNQLILR	CCDC40	641	Q4G0X9
RKKVFRKNYSRNNIT	FAT3	4176	Q8TDW7
QQNRSARQSAYIRKK	DNAAF9	806	Q5TEA3
NRQSLLSFFQKRIYK	DNAH14	2121	Q0VDD8
VTKNYRGVKITNFTT	EHBP1	456	Q8NDI1
NRNMKVYQKTTFSSR	CCDC38	51	Q502W7
TKQNNSFQRSKRRYF	DGKD	61	Q16760
NIASATKFKQLYRSR	HMOX1	171	P09601
NRKQISAIATQGRYS	CNTNAP2	91	Q9UHC6
KSINKNTVTVRGYSQ	ESCO1	81	Q5FWF5
NSNRYERLKATQVSK	GSN	231	P06396
RSNYALKILQFTRNG	GRIK4	371	Q16099
RKQSRIYSNAKNTEA	COLGALT2	596	Q8IYK4
AIKTLRKSIGRQQFY	SCUBE1	581	Q8IWY4
NAKRAITYQIAKNRG	UTP3	406	Q9NQZ2
ASRQINSYVKNKTQG	SERPINA6	166	P08185
RNRNFRLYKSSKIGK	PRIMPOL	286	Q96LW4
FRYIRNTVGQKNLAS	TMEM67	971	Q5HYA8
GQKQRVSLARAVYSN	ABCC1	771	P33527
RKRIAANIYNKQSFT	KIF13A	1271	Q9H1H9
ANIYNKQSFTQSLKR	KIF13A	1276	Q9H1H9
SATGQKLYVRLFQRK	FAN1	411	Q9Y2M0
RTKNNIQRYFGTNSV	MRPS31	51	Q92665
RNSNTSKQRYSGKVH	RIMBP2	156	O15034
KQGKRLNFTQSYSLQ	SLAMF6	81	Q96DU3
SENKLSRRQTQAKYG	PRCC	476	Q92733
RKASISYFKNQRGIQ	SMARCAD1	76	Q9H4L7
GFTKKRNNQIRKTSY	RPS3A	141	P61247
SSSSQQNYGLRAKRK	NEXMIF	471	Q5QGS0
NSVYDNVRSVGKRKQ	OVCH1	1086	Q7RTY7
KLYQSATQAVFQKRQ	RABGGTA	26	Q92696
DYFAQKQRKLNRRTS	MAPKAP1	496	Q9BPZ7
GVSTVGYRNKNVRQK	CCDC59	21	Q9P031
YSQNVRSKNKRSFRE	SDAD1	656	Q9NVU7
NRRKYITKNVTGFFQ	SLCO1B7	266	G3V0H7
QRLARKTNKQVFVSY	PSMG4	81	Q5JS54
QKFGYSVNRKRLNRN	NOP16	11	Q9Y3C1
TQYTQRKFQKSRQPR	ARHGAP4	481	P98171
YNISVFSVKRNSNNK	SNED1	976	Q8TER0
RNGQKEALLKYRQST	ARID5B	136	Q14865
AGRKIYRSNQVEKFT	ZNF610	141	Q8N9Z0
LLQQDVKKRRSYGNS	SELENOK	41	Q9Y6D0
NIKDSFQKVTLRRYG	ZNF107	21	Q9UII5
TKYIKFTGNQIQNRI	TRIM24	281	O15164
RGSATNYITRNKARK	PES1	11	O00541
RQKRRGAFNSKQLLY	PTP4A2	131	Q12974
AKSKLTRNNFAVGYR	VDAC2	171	P45880
NYSKVNNSNKRRRFS	ZNF518A	641	Q6AHZ1
EIKKRFQTTYGSRAQ	VAMP7	81	P51809
NSTYNARVKAFNKTG	TRIM9	506	Q9C026
SLTTTQSKVFQRGKY	ZNF208	136	O43345
QQSYAKQRRSKSAAL	ZZEF1	2576	O43149
NTAGISQYLQNSKRK	KDR	1216	P35968
KTIVSKNALQYRGNS	USP31	211	Q70CQ4
KTRISNKYRNNFLQS	ZNF701	251	Q9NV72
NRSQGNIISYKRRIS	TMEM217	156	Q8N7C4
TRFIATLKQKYTQSN	PSMA8	116	Q8TAA3
TLKQKYTQSNGRRPF	PSMA8	121	Q8TAA3
KARVQFGANKSQYSL	UBE2Q1	381	Q7Z7E8
RSTSLKYSKIRQFQE	ZC3H7B	596	Q9UGR2
SVYRNKKLRNAGNIF	MTNR1A	51	P48039
YKNKNGQLTVVSVRR	MYO1H	1016	Q8N1T3
KTVRNNNSSRFGKFV	MYO6	196	Q9UM54