Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	4.47e-07	5	72	3	GO:0030156
GeneOntologyMolecularFunction	nuclear estrogen receptor binding	NCOA2 NCOA3 NCOA6 DDX54	3.98e-05	53	72	4	GO:0030331
GeneOntologyMolecularFunction	chromatin binding	MPO NCOA2 CCNT2 NCOA3 NCOA6 TDRD3 PCGF1 PATZ1 POLR2A PKN1 ARID3C	6.39e-05	739	72	11	GO:0003682
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	NCOA2 NCOA3 NCOA6 PKN1	6.94e-05	61	72	4	GO:0030374
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	NCOA2 NCOA3 NCOA6	2.48e-04	34	72	3	GO:0046966
GeneOntologyMolecularFunction	nuclear receptor binding	NCOA2 NCOA3 NCOA6 DDX54 PKN1	5.75e-04	187	72	5	GO:0016922
GeneOntologyCellularComponent	manchette	RIMBP3 CCDC42 RIMBP3C RIMBP3B	2.63e-06	28	73	4	GO:0002177
HumanPheno	Dysplastic granulopoesis	TET2 SRP68	3.53e-05	3	18	2	HP:0012136
MousePheno	detached acrosome	RIMBP3 NCOA2 CCDC42 RIMBP3C RIMBP3B	9.90e-07	44	58	5	MP:0009231
MousePheno	ectopic manchette	RIMBP3 RIMBP3C RIMBP3B	6.27e-05	19	58	3	MP:0009377
MousePheno	detached sperm flagellum	RIMBP3 RIMBP3C RIMBP3B	8.55e-05	21	58	3	MP:0008893
Domain	FN3	RIMBP3 PTPRB ROBO1 NCAM2 RIMBP3C TEK RIMBP3B	1.05e-05	199	71	7	PS50853
Domain	DUF4927	NCOA2 NCOA3	1.42e-05	2	71	2	PF16279
Domain	DUF4927	NCOA2 NCOA3	1.42e-05	2	71	2	IPR032565
Domain	FN3_dom	RIMBP3 PTPRB ROBO1 NCAM2 RIMBP3C TEK RIMBP3B	1.44e-05	209	71	7	IPR003961
Domain	DUF1518	NCOA2 NCOA3	4.26e-05	3	71	2	PF07469
Domain	DUF1518	NCOA2 NCOA3	4.26e-05	3	71	2	IPR010011
Domain	Nuc_rcpt_coact_Ncoa-typ	NCOA2 NCOA3	4.26e-05	3	71	2	IPR014920
Domain	SRC-1	NCOA2 NCOA3	4.26e-05	3	71	2	IPR014935
Domain	Src1_rcpt_coact	NCOA2 NCOA3	4.26e-05	3	71	2	IPR008955
Domain	Nuclear_rcpt_coactivator	NCOA2 NCOA3	4.26e-05	3	71	2	IPR017426
Domain	DUF1518	NCOA2 NCOA3	4.26e-05	3	71	2	SM01151
Domain	SRC-1	NCOA2 NCOA3	4.26e-05	3	71	2	PF08832
Domain	-	NCOA2 NCOA3	4.26e-05	3	71	2	4.10.630.10
Domain	Nuc_rec_co-act	NCOA2 NCOA3	4.26e-05	3	71	2	PF08815
Domain	FN3	PTPRB ROBO1 NCAM2 RIMBP3C TEK RIMBP3B	7.31e-05	185	71	6	SM00060
Domain	Nuc_rcpt_coact	NCOA2 NCOA3	2.12e-04	6	71	2	IPR009110
Domain	BAR	ARHGAP44 ACAP2	2.34e-03	19	71	2	PS51021
Domain	SH3_9	RIMBP3 RIMBP3C RIMBP3B	3.27e-03	78	71	3	PF14604
Domain	fn3	PTPRB ROBO1 NCAM2 TEK	3.37e-03	162	71	4	PF00041
Domain	PAS	NCOA2 NCOA3	4.04e-03	25	71	2	PF00989
Domain	PAS_fold	NCOA2 NCOA3	4.04e-03	25	71	2	IPR013767
Domain	SH3_2	RIMBP3 RIMBP3C RIMBP3B	4.30e-03	86	71	3	IPR011511
Domain	SH3_2	RIMBP3 RIMBP3C RIMBP3B	4.30e-03	86	71	3	PF07653
Domain	ArfGap	ACAP2 ARAP1	5.41e-03	29	71	2	SM00105
Domain	ArfGap	ACAP2 ARAP1	5.41e-03	29	71	2	PF01412
Domain	ARFGAP	ACAP2 ARAP1	5.41e-03	29	71	2	PS50115
Domain	ArfGAP	ACAP2 ARAP1	5.41e-03	29	71	2	IPR001164
Domain	-	ARHGAP44 ACAP2	5.79e-03	30	71	2	1.20.1270.60
Domain	AH/BAR-dom	ARHGAP44 ACAP2	5.79e-03	30	71	2	IPR027267
Domain	PAS	NCOA2 NCOA3	6.57e-03	32	71	2	SM00091
Domain	PAS	NCOA2 NCOA3	7.39e-03	34	71	2	IPR000014
Domain	PAS	NCOA2 NCOA3	7.39e-03	34	71	2	PS50112
Pathway	PID_ERB_GENOMIC_PATHWAY	NCOA2 NCOA3 DDX54	1.74e-05	15	49	3	M119
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	3.54e-08	4	73	3	19091768
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	8.84e-08	5	73	3	17855024
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 CCDC88C NCOA3 TDRD3 KIF23 G3BP1 PATZ1 KIF21A ARHGAP44 ELAVL2 DNM1L PKN1 PCM1	9.64e-08	963	73	13	28671696
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	NCOA2 KIF23 PCGF1 TSR1 POLR2A KCMF1 ANKRD26 SRP68 ACAP2 EDRF1 PCM1	1.03e-07	645	73	11	25281560
Pubmed	Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3.	NCOA3 NR2E3 POLR2A	1.77e-07	6	73	3	15919092
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TDRD3 VPS52 KIF23 TRAPPC12 POLR2A SRP68 ROBO1 RNF40 CHTOP PCM1 SLC27A4	3.67e-07	733	73	11	34672954
Pubmed	The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.	NCOA2 NCOA3 NCOA6	1.45e-06	11	73	3	36613751
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PTOV1 TET2 CCDC88C NCOA6 KIF23 PATZ1 ANKRD26 DNM1L RNF180 EDRF1 PCM1	1.77e-06	861	73	11	36931259
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	3.18e-06	14	73	3	17662146
Pubmed	TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1.	TDRD3 G3BP1	4.35e-06	2	73	2	35085371
Pubmed	Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis.	NCOA2 NCOA3	4.35e-06	2	73	2	21220509
Pubmed	Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Distinct Entity Characterized by Recurrent NCOA2/3 Gene Fusions.	NCOA2 NCOA3	4.35e-06	2	73	2	30273195
Pubmed	The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1.	DNM1L MFF	4.35e-06	2	73	2	26446846
Pubmed	Tyrosine phosphatase beta regulates angiopoietin-Tie2 signaling in human endothelial cells.	PTPRB TEK	4.35e-06	2	73	2	19116766
Pubmed	Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division.	DNM1L MFF	4.35e-06	2	73	2	34347505
Pubmed	Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity.	DNM1L MFF	4.35e-06	2	73	2	26578513
Pubmed	Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor.	DNM1L MFF	4.35e-06	2	73	2	26578514
Pubmed	Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo.	DNM1L MFF	4.35e-06	2	73	2	30232469
Pubmed	A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.	NCOA2 NCOA3	4.35e-06	2	73	2	30048685
Pubmed	Recognition of asymmetrically dimethylated arginine by TDRD3.	TDRD3 POLR2A	4.35e-06	2	73	2	23066109
Pubmed	Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer.	NCOA3 NCOA6	4.35e-06	2	73	2	8758910
Pubmed	Shear stress control of vascular leaks and atheromas through Tie2 activation by VE-PTP sequestration.	PTPRB TEK	4.35e-06	2	73	2	36740996
Pubmed	Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.	PTPRB TEK	4.35e-06	2	73	2	31621585
Pubmed	Effects of a Levonorgestrel-Releasing Intrauterine System on the Expression of Steroid Receptor Coregulators in Adenomyosis.	NCOA2 NCOA3	4.35e-06	2	73	2	26040939
Pubmed	Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature.	PTPRB TEK	4.35e-06	2	73	2	25180601
Pubmed	Human transcription factor protein interaction networks.	NCOA2 TET2 NCOA3 NCOA6 KIF23 PCGF1 G3BP1 KCMF1 DDX54 ELAVL2 SRP68 PSMD2 PCM1	7.81e-06	1429	73	13	35140242
Pubmed	Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.	NCOA2 NCOA3 POLR2A	8.39e-06	19	73	3	14578343
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	G3BP1 TSR1 POLR2A DDX54 SRP68 PSMD2 RNF40 RBM23 CHTOP	9.14e-06	653	73	9	33742100
Pubmed	The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription.	NCOA2 NCOA3 POLR2A	9.86e-06	20	73	3	16957778
Pubmed	T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.	NCOA2 NCOA3 NCOA6	9.86e-06	20	73	3	11877444
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CCNT2 NCOA6 KIF23 G3BP1 TSR1 KIF21A POLR2A KCMF1 DDX54 SRP68 PSMD2 CHTOP	1.04e-05	1247	73	12	27684187
Pubmed	Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.	NCOA2 NCOA3 NCOA6	1.15e-05	21	73	3	19596656
Pubmed	Heterogeneity of endothelial VE-PTP downstream polarization, Tie2 activation, junctional claudin-5, and permeability in the aorta and vena cava.	PTPRB TEK	1.30e-05	3	73	2	38032480
Pubmed	The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves' disease in the Chinese population.	PTPRB TRAF3IP3	1.30e-05	3	73	2	36397361
Pubmed	TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression.	DNM1L MFF	1.30e-05	3	73	2	23284813
Pubmed	The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.	NCOA2 NCOA3	1.30e-05	3	73	2	21035760
Pubmed	VE-PTP controls blood vessel development by balancing Tie-2 activity.	PTPRB TEK	1.30e-05	3	73	2	19451274
Pubmed	Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.	NCOA2 NCOA3	1.30e-05	3	73	2	21059860
Pubmed	SENP3-mediated deSUMOylation of Drp1 facilitates interaction with Mff to promote cell death.	DNM1L MFF	1.30e-05	3	73	2	28262828
Pubmed	Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis.	NCOA2 NCOA3	1.30e-05	3	73	2	21735116
Pubmed	Pkn is a novel partner of cyclin T2a in muscle differentiation.	CCNT2 PKN1	1.30e-05	3	73	2	16331689
Pubmed	Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.	NCOA2 NCOA3	1.30e-05	3	73	2	16675958
Pubmed	A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission.	DNM1L MFF	1.30e-05	3	73	2	30059978
Pubmed	FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.	NCOA2 NCOA3	1.30e-05	3	73	2	15698540
Pubmed	Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.	NCOA2 NCOA3	1.30e-05	3	73	2	9506940
Pubmed	Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.	NCOA2 NCOA3	1.30e-05	3	73	2	28390937
Pubmed	Estrogen signaling in colorectal carcinoma microenvironment: expression of ERbeta1, AIB-1, and TIF-2 is upregulated in cancer-associated myofibroblasts and correlates with disease progression.	NCOA2 NCOA3	1.30e-05	3	73	2	19277704
Pubmed	Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.	NCOA2 NCOA3	1.30e-05	3	73	2	23927929
Pubmed	The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria.	DNM1L MFF	1.30e-05	3	73	2	31533986
Pubmed	Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.	NCOA2 NCOA3	1.30e-05	3	73	2	19052561
Pubmed	Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2.	PTPRB TEK	1.30e-05	3	73	2	10557082
Pubmed	COX assembly factor ccdc56 regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1.	DNM1L MFF	1.30e-05	3	73	2	26358295
Pubmed	Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2.	PTPRB TEK	1.30e-05	3	73	2	31427368
Pubmed	Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.	NCOA2 NCOA3	1.30e-05	3	73	2	18845648
Pubmed	The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.	NCOA2 NCOA3	1.30e-05	3	73	2	12138202
Pubmed	The nuclear receptor coactivators p300/CBP/cointegrator-associated protein (p/CIP) and transcription intermediary factor 2 (TIF2) differentially regulate PKA-stimulated transcriptional activity of steroidogenic factor 1.	NCOA2 NCOA3	1.30e-05	3	73	2	11923473
Pubmed	Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.	PTPRB TEK	1.30e-05	3	73	2	26642851
Pubmed	Structure and chromosomal locations of mouse steroid receptor coactivator gene family.	NCOA2 NCOA3	1.30e-05	3	73	2	10501088
Pubmed	Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway.	DNM1L MFF	1.30e-05	3	73	2	29725013
Pubmed	The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.	DNM1L MFF	1.30e-05	3	73	2	18353969
Pubmed	The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.	NCOA2 NCOA3	1.30e-05	3	73	2	16423883
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TDRD3 KIF23 G3BP1 TSR1 KIF21A SRP68 DNM1L ROBO1 PSMD2 GALNT7 MFF PCM1	1.54e-05	1297	73	12	33545068
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA2 TET2 NCOA3 NCOA6 PCGF1 RNF40	2.19e-05	268	73	6	33640491
Pubmed	miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.	NCOA2 NCOA3	2.60e-05	4	73	2	26066330
Pubmed	Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission.	DNM1L MFF	2.60e-05	4	73	2	21701560
Pubmed	The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.	CCNT2 POLR2A	2.60e-05	4	73	2	18566585
Pubmed	P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.	NCOA2 NCOA3	2.60e-05	4	73	2	18267973
Pubmed	Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells.	NCOA2 NCOA3	2.60e-05	4	73	2	15331759
Pubmed	Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2.	NCOA2 NCOA3	2.60e-05	4	73	2	10598588
Pubmed	Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission.	DNM1L MFF	2.60e-05	4	73	2	27076521
Pubmed	Characterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cells.	NCOA2 NCOA3	2.60e-05	4	73	2	19462000
Pubmed	Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.	NCOA2 NCOA3	2.60e-05	4	73	2	19095746
Pubmed	Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells.	DNM1L MFF	2.60e-05	4	73	2	21149567
Pubmed	Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation.	NCOA2 NCOA3	2.60e-05	4	73	2	12893883
Pubmed	Estrogen receptor alpha/beta, AIB1, and TIF2 in colorectal carcinogenesis: do coregulators have prognostic significance?	NCOA2 NCOA3	2.60e-05	4	73	2	19198856
Pubmed	Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.	NCOA2 NCOA3	2.60e-05	4	73	2	22560224
Pubmed	Transcriptional activity and substrate recognition of cyclin T2 from P-TEFb.	CCNT2 POLR2A	2.60e-05	4	73	2	15563843
Pubmed	Interactions of RXR with coactivators are differentially mediated by helix 11 of the receptor's ligand binding domain.	NCOA2 NCOA3	2.60e-05	4	73	2	11851396
Pubmed	Substrate specificities and activities of AZAP family Arf GAPs in vivo.	ACAP2 ARAP1	2.60e-05	4	73	2	18003747
Pubmed	Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.	NCOA2 NCOA3	2.60e-05	4	73	2	26267537
Pubmed	Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission.	DNM1L MFF	2.60e-05	4	73	2	23530241
Pubmed	The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor.	NCOA2 NCOA3	2.60e-05	4	73	2	15563469
Pubmed	Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.	NCOA2 NCOA3	2.60e-05	4	73	2	15563453
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA2 NCOA3 NCOA6 PCGF1	2.90e-05	83	73	4	28794006
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	VPS52 KIF23 ANKRD26 SRP68 DNM1L ROBO1 PKN1 MFF PCM1	3.59e-05	777	73	9	35844135
Pubmed	Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene.	NCOA2 NCOA3	4.33e-05	5	73	2	10652338
Pubmed	Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members.	NCOA2 NCOA3	4.33e-05	5	73	2	17950690
Pubmed	SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.	NCOA2 NCOA3	4.33e-05	5	73	2	17476305
Pubmed	Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function.	NCOA2 NCOA3	4.33e-05	5	73	2	17854779
Pubmed	Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes.	NCOA2 NCOA3	4.33e-05	5	73	2	18511550
Pubmed	Estrogen receptor-alpha interaction with the CREB binding protein coactivator is regulated by the cellular environment.	NCOA2 NCOA3	4.33e-05	5	73	2	14766010
Pubmed	Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease.	DNM1L MFF	4.33e-05	5	73	2	29464060
Pubmed	Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.	DNM1L MFF	4.33e-05	5	73	2	23283981
Pubmed	Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.	NCOA2 NCOA3	4.33e-05	5	73	2	12714702
Pubmed	Regulation of transcription by a protein methyltransferase.	NCOA2 NCOA3	4.33e-05	5	73	2	10381882
Pubmed	SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells.	NCOA2 NCOA3	4.33e-05	5	73	2	12514218
Pubmed	Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes.	NCOA2 NCOA3	4.33e-05	5	73	2	11376110
Pubmed	Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter.	NCOA3 POLR2A	4.33e-05	5	73	2	15863722
Pubmed	Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.	NCOA2 NCOA3	4.33e-05	5	73	2	18798693
Pubmed	Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.	NCOA2 NCOA3	4.33e-05	5	73	2	12554772
Interaction	RASSF9 interactions	PTOV1 G3BP1 KCMF1 CCDC85B	1.06e-05	39	71	4	int:RASSF9
Interaction	SMG7 interactions	NCOA2 NCOA3 NCOA6 TDRD3 G3BP1 TSR1 RNF40 PCM1	1.62e-05	319	71	8	int:SMG7
Interaction	YWHAH interactions	NCOA2 PTOV1 TET2 CCDC88C NCOA3 NCOA6 KIF23 G3BP1 ANKRD26 DNM1L PSMD2 NCAM2 EDRF1 PCM1	2.54e-05	1102	71	14	int:YWHAH
Interaction	EGR2 interactions	NCOA2 TET2 NCOA3 NCOA6 PCGF1 RNF40	3.10e-05	171	71	6	int:EGR2
Interaction	ALG13 interactions	NCOA2 NCOA3 TDRD3 PCGF1 ELAVL2 PCM1	4.53e-05	183	71	6	int:ALG13
Interaction	KLF5 interactions	NCOA2 TET2 NCOA3 NCOA6 PCGF1 G3BP1	6.45e-05	195	71	6	int:KLF5
Interaction	CCDC138 interactions	TDRD3 KIF23 PKN1 TRAF3IP3 PCM1	7.36e-05	123	71	5	int:CCDC138
Interaction	IBTK interactions	TDRD3 PCGF1 G3BP1 TSR1 PCM1	8.26e-05	126	71	5	int:IBTK
Interaction	FLII interactions	NCOA2 NCOA3 TDRD3 TSR1 TMOD4 SRP68 OTUD3	8.53e-05	298	71	7	int:FLII
Interaction	VDR interactions	NCOA2 NCOA3 NCOA6 NR2E3 POLR2A	8.57e-05	127	71	5	int:VDR
Interaction	BBLN interactions	RNF40 PCM1 SLC27A4	9.12e-05	25	71	3	int:BBLN
Interaction	SOX2 interactions	NCOA2 TET2 NCOA3 NCOA6 KIF23 PCGF1 G3BP1 PATZ1 KCMF1 ANKRD26 SRP68 DNM1L PSMD2 CHTOP CCDC85B	1.06e-04	1422	71	15	int:SOX2
Interaction	WDR5 interactions	TET2 NCOA6 NR2E3 KIF23 G3BP1 TSR1 DDX54 SRP68 DNM1L PSMD2 PKN1 CHTOP GFM2	1.08e-04	1101	71	13	int:WDR5
Interaction	ERG interactions	NCOA2 TET2 NCOA3 NCOA6 PCGF1 POLR2A	1.35e-04	223	71	6	int:ERG
Interaction	ZNF326 interactions	KIF23 PCGF1 POLR2A ELAVL2 RNF40 TEK	1.38e-04	224	71	6	int:ZNF326
GeneFamily	Fibronectin type III domain containing	PTPRB ROBO1 NCAM2 TEK	4.21e-04	160	40	4	555
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	NCOA2 NCOA3	6.36e-04	17	40	2	486
GeneFamily	Basic helix-loop-helix proteins	NCOA2 NCOA3 MSC	1.84e-03	110	40	3	420
GeneFamily	Ankyrin repeat domain containing	ANKDD1A ANKRD26 ACAP2 ARAP1	1.96e-03	242	40	4	403
GeneFamily	ArfGAPs	ACAP2 ARAP1	2.41e-03	33	40	2	395
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF23 KIF21A	4.64e-03	46	40	2	622
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 ELAPOR2 PTPRB TEK FAM167B	1.05e-05	176	73	5	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 ELAPOR2 PTPRB TEK FAM167B	1.05e-05	176	73	5	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC88C ELAVL2 TEK CCDC85B FAM167B	1.11e-05	178	73	5	60263c0bb9de3a57ba2ba543262a2ace0066fd85
ToppCell	facs-Kidney-nan-18m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 PTPRB TEK CCDC85B FAM167B	1.59e-05	192	73	5	777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCell	facs-Kidney-nan-18m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 PTPRB TEK CCDC85B FAM167B	1.59e-05	192	73	5	60a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCell	facs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 PTPRB TEK CCDC85B FAM167B	1.59e-05	192	73	5	0f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCell	Caecum-B_cell-B_cell_IgG_Plasma\|B_cell / Region, Cell class and subclass	NCOA2 TMEM171 SRP68 RIMBP3C B4GALNT3	1.80e-05	197	73	5	40c8ff067e8242e2ca083ea04cd6026168191a97
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC88C PTPRB TEK CCDC85B FAM167B	1.80e-05	197	73	5	f4834378d5d31560b4efe5dee0d5b5d11caeb10f
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A ARHGAP44 LAMC2 B4GALNT3	1.17e-04	153	73	4	e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WNT5B CCDC42 ANKDD1A NCAM2	1.20e-04	154	73	4	3c9d38709f507e91ec3bcc6184cbbfa9b1250128
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WNT5B CCDC42 ANKDD1A NCAM2	1.20e-04	154	73	4	1ad4152a3e4bf5912954235fe21c2447e99f3de7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB ELAVL2 PKN1 TEK	1.35e-04	159	73	4	c960df9e4fa980401941866b5081facac4590b4d
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WNT5B BICDL2 SEL1L3 B4GALNT3	1.42e-04	161	73	4	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	facs-Skin-Anagen-3m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAM2 B4GALNT3 TEK RNF180	1.42e-04	161	73	4	8d2987271da52fd8353557ac6faa4f7a4be0ed2a
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NR2E3 PTPRB ANKDD1A TEK	1.60e-04	166	73	4	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C TMOD4 TRAF3IP3 FAAH	1.67e-04	168	73	4	1df3c8c7a6dceb901805eaba7f86f9943f4f1a9d
ToppCell	droplet-Lung-nan-3m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C TMOD4 TRAF3IP3 FAAH	1.67e-04	168	73	4	1586451d437b70b2dffe41d782b694702dcaf50b
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRB TEK CCDC85B FAM167B	1.75e-04	170	73	4	1a568efcff9c39b3f709b55a05d24710450a2657
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TMEM171 SAMD10 ARHGAP44 LAMC2	1.75e-04	170	73	4	5a64e05c263df915085988d881808221e2c0f2e2
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRB TEK CCDC85B FAM167B	1.75e-04	170	73	4	66d41d794790e621d72ac37af995510537103c9c
ToppCell	COVID-19-kidney-Plasma\|kidney / Disease (COVID-19 only), tissue and cell type	WNT5B CCDC88C NCOA3 SEL1L3	1.79e-04	171	73	4	a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC88C TMOD4 TRAF3IP3 FAAH	1.83e-04	172	73	4	425970e9ce8943f7e2ba6ca958e7a3a29baa798c
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC88C TMOD4 TRAF3IP3 FAAH	1.83e-04	172	73	4	ca0cc0e92b6cdce5016f18fcb2ec1508cb222502
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB DMRTC2 TEK CCDC85B	1.87e-04	173	73	4	3877cead288ce9509e6cccf57e55ec5e1bd7ce18
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ELAPOR2 KIF21A ARHGAP44 LAMC2	1.91e-04	174	73	4	d0e3d15731de6c19c232e3aa492c39d8151cf4ed
ToppCell	Control-B_cells-Plasma_cells\|Control / group, cell type (main and fine annotations)	WNT5B CCDC88C NCOA3 SEL1L3	1.95e-04	175	73	4	fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ELAPOR2 ARHGAP44 LAMC2 SLC27A4	1.95e-04	175	73	4	96219e58dcb327fd27190be78193e7a0d611e62b
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ELAPOR2 ARHGAP44 LAMC2 SLC27A4	1.95e-04	175	73	4	cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PTOV1 VPS52 PATZ1 ANKRD26	1.95e-04	175	73	4	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRB TEK CATSPERG FAM167B	1.95e-04	175	73	4	7be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	CCDC88C NCOA3 SEL1L3 TRAF3IP3	2.04e-04	177	73	4	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB TEK CCDC85B FAM167B	2.08e-04	178	73	4	5636f2e89027955f406d420ff6df6a4b8c12cb20
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNT5B CCDC88C NCOA3 SEL1L3	2.08e-04	178	73	4	f815bc76f98aaea2d9058173b02b6f36e45283ce
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNT5B CCDC88C NCOA3 SEL1L3	2.08e-04	178	73	4	a0334764e865fea652c54b94bbc3b173f7cbc9fc
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCDC88C ELAPOR2 TMEM171 KIF21A	2.13e-04	179	73	4	bc95c3e7edc5fc6fc913b09f087d221df64c6f48
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	KIF23 POLR2A ELAVL2 LAMC2	2.13e-04	179	73	4	83506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCell	facs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTOV1 G3BP1 ARHGAP44 ELAVL2	2.22e-04	181	73	4	064057ab36c6d92c36572b73142b42d201709d7b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.22e-04	181	73	4	4a225d9a6d113396c6b1d0a839bb4ca9c339a260
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 PTPRB CCDC85B FAM167B	2.27e-04	182	73	4	000ff26c51c6a1ea8770c02722523e55be83b46f
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WNT5B BICDL2 SEL1L3 B4GALNT3	2.27e-04	182	73	4	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	facs-Liver-Liver_non-hepato/SCs_st\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 PTPRB CCDC85B FAM167B	2.27e-04	182	73	4	b906e6e584ecbe92d3030bbdc4426f244fbe0045
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 PTPRB TEK FAM167B	2.27e-04	182	73	4	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB ROBO1 TEK FAM167B	2.32e-04	183	73	4	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB ROBO1 TEK FAM167B	2.32e-04	183	73	4	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TMEM171 SAMD10 KIF21A LAMC2	2.32e-04	183	73	4	031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.32e-04	183	73	4	858682df5592c6856487487a7baabd6e60e63a38
ToppCell	3'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.32e-04	183	73	4	f8212bf8a8b8312434ae030261c558c147f61747
ToppCell	COVID-19-B_cells-Plasma_cells\|COVID-19 / group, cell type (main and fine annotations)	WNT5B CCDC88C NCOA3 SEL1L3	2.32e-04	183	73	4	130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCell	COVID-19-B_cells\|COVID-19 / group, cell type (main and fine annotations)	WNT5B CCDC88C NCOA3 SEL1L3	2.32e-04	183	73	4	2c016bb59f131a0e821853b085289a3583f0a729
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.36e-04	184	73	4	fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.36e-04	184	73	4	df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.36e-04	184	73	4	1ace70f12b417185bdd46042833f72b3b6815966
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC88C NCOA3 SEL1L3 TRAF3IP3	2.36e-04	184	73	4	f81209e6bc01a0140f4487aa8b22eb02fbf0c39c
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	WNT5B CCDC88C NCOA3 SEL1L3	2.41e-04	185	73	4	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.41e-04	185	73	4	0ab1be455f2cd883c9d1522ca78112c37833352e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.46e-04	186	73	4	e9d12f2fcd346fc8d00f7178324ea5997628df8a
ToppCell	E17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTPRB TEK CCDC85B FAM167B	2.51e-04	187	73	4	e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCell	E17.5-Endothelial-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTPRB TEK CCDC85B FAM167B	2.51e-04	187	73	4	61b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.51e-04	187	73	4	f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC88C PTPRB TEK CCDC85B	2.51e-04	187	73	4	0ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB TEK CCDC85B FAM167B	2.51e-04	187	73	4	a555a4af7946dec14a6b176ace4a4c2ecfd7f59e
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.51e-04	187	73	4	fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.51e-04	187	73	4	d6765854154557794815514c0aa355bc74b8523e
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.57e-04	188	73	4	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.57e-04	188	73	4	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PTPRB SEL1L3 TEK FAM167B	2.57e-04	188	73	4	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNT5B CCDC88C PTPRB TEK	2.57e-04	188	73	4	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	facs-Kidney-nan-24m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.62e-04	189	73	4	9d02a824bba59ea0660439f0510d843568e9d8c3
ToppCell	facs-Kidney-nan-24m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.62e-04	189	73	4	5f8d4b61296c71b32362432a9ce4c1c3aaeb278d
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC88C PTPRB TEK CCDC85B	2.62e-04	189	73	4	9e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCell	3'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.62e-04	189	73	4	0c612ff5f882f2d8ec744a347780bbbe7cc471bd
ToppCell	facs-Kidney-nan-24m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.62e-04	189	73	4	18f82764b32496e54d1a604a531b261651c5e110
ToppCell	3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.62e-04	189	73	4	bc8949bd4f425ed36e2c05e653c94cb1593c5bee
ToppCell	E17.5-Endothelial\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTPRB TEK CCDC85B FAM167B	2.67e-04	190	73	4	4fb76195ec9d6e0260a628eef6c2b3705acce787
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.67e-04	190	73	4	d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CCDC88C PTPRB SEL1L3 TEK	2.67e-04	190	73	4	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRB TEK CCDC85B FAM167B	2.67e-04	190	73	4	106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNT5B PTPRB TEK CCDC85B	2.78e-04	192	73	4	bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRB ROBO1 TEK FAM167B	2.78e-04	192	73	4	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	e4dd24aefdf13cd4206714f02fde2288f3173ffc
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	1a2dd398141069ef6ad2f6bb4bae0bac1c6b98e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB NCAM2 TEK FAM167B	2.78e-04	192	73	4	25cb6cc6cbf8dc20139d938adfc02ed7a8c3dfb6
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	5dd206adb8b84c374ee931f7df2a8b8cf040efab
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	5890076929598e88fe9d59a4e4e858b446746ce9
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Early_cap\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	4986ef70a665fdfa1df86f7f8a15117487eae159
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRB TEK CCDC85B FAM167B	2.78e-04	192	73	4	3c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCell	(4)_Endothelial_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	PTPRB TEK CCDC85B FAM167B	2.83e-04	193	73	4	ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB TEK CCDC85B FAM167B	2.83e-04	193	73	4	daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.83e-04	193	73	4	4a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PTPRB SEL1L3 TEK FAM167B	2.83e-04	193	73	4	643f992dbce639e7d147924d8b8f455fcebf215a
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB TEK CCDC85B FAM167B	2.83e-04	193	73	4	d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.83e-04	193	73	4	dd443b83d328a9069ffe19ac3d74066e922515a5
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PTPRB SEL1L3 TEK FAM167B	2.83e-04	193	73	4	72d20ee257149b238016b44d183ce3fc24b8f621
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CCDC88C TMEM171 ARHGAP44 LAMC2	2.83e-04	193	73	4	c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCell	E16.5-samps-Epithelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CCDC88C TMEM171 ARHGAP44 LAMC2	2.83e-04	193	73	4	1cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB TEK CCDC85B FAM167B	2.83e-04	193	73	4	1b69f92c6a7a2516e393d3f3c371407ec791343d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB ROBO1 TEK FAM167B	2.83e-04	193	73	4	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	COVID-CD8-CD8_1\|COVID / Condition, Cell_class and T cell subcluster	CCDC88C MSC KIF21A TRAF3IP3	2.83e-04	193	73	4	221690901cb214c8ee186ff527c80dcc52d1fb1c
Disease	tonsillectomy risk measurement	NCOA2 TET2 SAMD10 RNF40 ACAP2	3.16e-04	260	67	5	EFO_0007924
Disease	mean platelet volume	TET2 TMEM171 POLR2A ANKDD1A DNM1L PSMD2 CATSPERG ACAP2 ARAP1	4.81e-04	1020	67	9	EFO_0004584
Disease	Malignant neoplasm of breast	NCOA2 NCOA3 NCOA6 HK3 TRAPPC12 TP53I3 ROBO1 TEK FAAH	6.96e-04	1074	67	9	C0006142
Disease	Hemangiosarcoma	PTPRB TEK	7.59e-04	18	67	2	C0018923
Disease	colorectal carcinoma (is_implicated_in)	NCOA2 PTPRB	1.14e-03	22	67	2	DOID:0080199 (is_implicated_in)
Disease	myeloperoxidase measurement	MPO PSMD2	1.59e-03	26	67	2	EFO_0005243
Disease	prostate carcinoma, breast carcinoma, ovarian carcinoma	TET2 CCDC88C	1.72e-03	27	67	2	EFO_0000305, EFO_0001075, EFO_0001663
Disease	upper respiratory tract disorder	TET2 RANBP6	1.85e-03	28	67	2	MONDO_0004867
Disease	D dimer measurement	ELAVL2 CATSPERG	2.12e-03	30	67	2	EFO_0004507
Disease	Prostatic Neoplasms	MPO NCOA2 TET2 NCOA3 VPS52 ROBO1	2.74e-03	616	67	6	C0033578
Disease	Malignant neoplasm of prostate	MPO NCOA2 TET2 NCOA3 VPS52 ROBO1	2.74e-03	616	67	6	C0376358

Protein segments in the cluster

Peptide	Gene	Start	Entry
QMNINGFLKRDRDNN	CATSPERG	201	Q6ZRH7
EDMQEQNGRLLQQLR	RNF40	766	O75150
CRQQAANLIQEMGQR	CCNT2	36	O60583
QRGRLMQEVNRQLQG	CCDC85B	41	Q15834
GLMNNNIEEQRRNRL	DNM1L	506	O00429
NNQNARMLEGRQTPA	B4GALNT3	446	Q6L9W6
MEALQKQQAARLAQG	ARID3C	1	A6NKF2
MGNSLLRENRRQQNT	GCSAM	1	Q8N6F7
LVNFMRAQRASQGGQ	DNHD1	1546	Q96M86
LQNGANVNQRDVQGR	ACAP2	661	Q15057
AQRQLSREQNARMLQ	ANKRD26	861	Q9UPS8
QQNNELARLQMRFDR	CCDC42	216	Q96M95
NRLAAMANNLQKGNG	RBM23	246	Q86U06
AGMNQDAVQNERQPR	NR2E3	111	Q9Y5X4
ASALNRADLMQRQGQ	TP53I3	36	Q53FA7
VLRLQRQLMLQQGNG	RIMBP3B	536	A6NNM3
VLRLQRQLMLQQGNG	RIMBP3C	536	A6NJZ7
ANLEANNNGRMRSLV	PTPRB	381	P23467
MSENAVRQNGQLVRN	MFF	156	Q9GZY8
IQLMLAQNANNRAAH	EDRF1	751	Q3B7T1
MGDEAQNLTRGRQQL	DDX54	716	Q8TDD1
QRTNALAMGENQRLR	CCDC88C	1241	Q9P219
MLQQQEQLRALQGRQ	PCM1	286	Q15154
RNLRNMSNQLGLLAV	MPO	351	P05164
RLNHDQLAAVQAQMR	HK3	491	P52790
RTNQGQDNRRFINDM	ELAPOR2	571	A8MWY0
LQRNLEQEQQQRGMG	PTOV1	401	Q86YD1
RMNQGKRNNAEENLE	OTUD3	271	Q5T2D3
MLHNLNQQRKNGGRF	PATZ1	26	Q9HBE1
NLALAQNRSQDVRMN	NCOA6	136	Q14686
MAAQVALRRQQEAQL	DMRTC2	81	Q8IXT2
GLLSNNNQALRRFMQ	G3BP1	96	Q13283
GGNQLFRINEANQLM	GALNT7	566	Q86SF2
SLQGENQMLQSRRQD	BICDL2	201	A1A5D9
AQQAQRFRLDNLLNM	ELAVL2	231	Q12926
QMQLQLERQHAQAAR	KCMF1	231	Q9P0J7
GRMQQAEQALQDILR	LAMC2	651	Q13753
QRQRAGLENMDRAAQ	FAAH	46	O00519
ELREMQAQDRQLAGQ	FAM167B	86	Q9BTA0
GGQIAIAMRLRNQLQ	PCGF1	6	Q9BSM1
RNHRLLNMARNNNDP	RNF180	161	Q86T96
GNRLREAGNINQSLM	KIF23	351	Q02241
RGNAAAQQRLAQMLF	SEL1L3	686	Q68CR1
QAMNPQDQNTLLNRR	GFM2	761	Q969S9
GARSNLNMNAAGNRN	TDRD3	156	Q9H7E2
LNMNAAGNRNREVLQ	TDRD3	161	Q9H7E2
VLRLQRQLMLQQGNG	RIMBP3	536	Q9UFD9
TNNARLAAMLRQLAQ	PSMD2	736	Q13200
RMQLQQRLQGQQFLN	NCOA3	1171	Q9Y6Q9
QRMGLAQEAQRQEVL	SAMD10	161	Q9BYL1
RMQLRRALQAGQLEN	PKN1	181	Q16512
NRMRQLANQTVGRAE	ARHGAP44	6	Q17R89
IAALLRTMENQGNQR	RANBP6	451	O60518
ENMAKGLQRALLQQQ	SRP68	396	Q9UHB9
EAARQNNVGRMQELI	ANKDD1A	21	Q495B1
QAGQTLQMEFLRNNR	ARAP1	706	Q96P48
MQQQQQLASARNRRL	CHTOP	41	Q9Y3Y2
NAQMLAQRQREILNQ	NCOA2	1231	Q15596
QGADSRDLQMNQALR	TRAF3IP3	351	Q9Y228
TLQEQSGAMNIRLRN	VPS52	146	Q8N1B4
ENRRQMQSRNERGCN	PRO0255	31	Q9UI72
QQEAGMLLRQLANQK	TSR1	226	Q2NL82
NRFAMLANNNLQILN	NCAM2	161	O15394
ILRMDPRNAVANNNA	TRAPPC12	646	Q8WVT3
NQHQVRMALGNGLRQ	SLC27A4	351	Q6P1M0
MVNQDRASQQINALR	KIF21A	376	Q7Z4S6
NDRNQGNQVERPQMT	SSX7	86	Q7RTT5
INNQLRRNEQNGAAA	POLR2A	286	P24928
EQGRVLMNLQNNEAG	WNT5B	191	Q9H1J7
QREQANVGRRNIAEM	ROBO1	1616	Q9Y6N7
AQLQLRAGLQRGQQM	TMEM171	81	Q8WVE6
NVQRRMAQAFQNVRE	TEK	776	Q02763
QQGPRARAAQAMTRN	TMOD4	321	Q9NZQ9
SQASQREGRLQQGNM	nan	291	A8MUI8
NVQMGLEEVQNINRR	TET2	801	Q6N021
QSQRNAANARERARM	MSC	106	O60682