Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphoglycerate kinase activity

PGK1 PGK2

1.79e-052852GO:0004618
GeneOntologyMolecularFunctionphosphotransferase activity, carboxyl group as acceptor

PGK1 PGK2

5.36e-053852GO:0016774
Domainzf-C2H2

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZHX2 ZNF439 ZNF850 ZKSCAN5 ZNF443

1.25e-056938413PF00096
DomainPGLYCERATE_KINASE

PGK1 PGK2

2.00e-052842PS00111
DomainPhosphoglycerate_kinase_N

PGK1 PGK2

2.00e-052842IPR015824
DomainPhosphoglycerate_kinase_CS

PGK1 PGK2

2.00e-052842IPR015911
DomainPhosphoglycerate_kinase_C

PGK1 PGK2

2.00e-052842IPR015901
Domain-

PGK1 PGK2

2.00e-0528423.40.50.1270
Domain-

PGK1 PGK2

2.00e-0528423.40.50.1260
DomainPGK

PGK1 PGK2

2.00e-052842PF00162
DomainZINC_FINGER_C2H2_2

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZHX2 ZNF439 ZNF850 ZKSCAN5 ZNF443

4.02e-057758413PS50157
DomainZINC_FINGER_C2H2_1

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZHX2 ZNF439 ZNF850 ZKSCAN5 ZNF443

4.13e-057778413PS00028
Domain-

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZNF439 ZNF850 ZKSCAN5 ZNF443

4.97e-0567984123.30.160.60
DomainZnf_C2H2-like

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZHX2 ZNF439 ZNF850 ZKSCAN5 ZNF443

5.29e-057968413IPR015880
DomainZnf_C2H2

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZHX2 ZNF439 ZNF850 ZKSCAN5 ZNF443

5.93e-058058413IPR007087
DomainPhosphoglycerate_kinase

PGK1 PGK2

5.98e-053842IPR001576
DomainZnf_C2H2/integrase_DNA-bd

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZNF439 ZNF850 ZKSCAN5 ZNF443

6.14e-056948412IPR013087
DomainZnF_C2H2

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 ZFHX4 GLIS3 ZNF528 ZHX2 ZNF439 ZNF850 ZKSCAN5 ZNF443

6.16e-058088413SM00355
DomainNxph

NXPH1 NXPH4

1.19e-044842IPR010450
DomainFG-GAP

GPLD1 FAM234A BBS2

1.66e-0424843PF01839
DomainFG-GAP

GPLD1 FAM234A BBS2

1.66e-0424843IPR013517
DomainCu_oxidase_CS

F5 HEPH

1.98e-045842IPR033138
DomainCu-oxidase_3

F5 HEPH

1.98e-045842IPR011707
DomainMULTICOPPER_OXIDASE1

F5 HEPH

1.98e-045842PS00079
DomainCu-oxidase_3

F5 HEPH

1.98e-045842PF07732
DomainCu_oxidase_Cu_BS

F5 HEPH

2.96e-046842IPR002355
DomainPSI

ATRN MET PLXNB1

3.96e-0432843PF01437
DomainPlexin_repeat

ATRN MET PLXNB1

3.96e-0432843IPR002165
DomainNXPH/NXPE

NXPH1 NXPH4

5.50e-048842IPR026845
DomainNeurexophilin

NXPH1 NXPH4

5.50e-048842PF06312
DomainPSI

ATRN MET PLXNB1

1.02e-0344843IPR016201
DomainKRAB

ZNF14 ZNF23 ZNF528 ZNF439 ZNF850 ZKSCAN5 ZNF443

1.15e-03358847PS50805
DomainPSI

ATRN MET PLXNB1

1.16e-0346843SM00423
DomainKRAB

ZNF14 ZNF23 ZNF528 ZNF439 ZNF850 ZKSCAN5 ZNF443

1.36e-03369847SM00349
DomainKRAB

ZNF14 ZNF23 ZNF528 ZNF439 ZNF850 ZKSCAN5 ZNF443

1.39e-03370847IPR001909
Domain-

F5 HEPH

1.76e-03148422.60.40.420
DomainConA-like_dom

TRIM41 PTPRU CLSTN1 BTN3A1 RYR2

3.09e-03219845IPR013320
DomainCupredoxin

F5 HEPH

4.36e-0322842IPR008972
DomainBRCT

LIG3 CTDP1

4.36e-0322842SM00292
DomainRRM_dom_euk

TIA1 TIAL1

4.76e-0323842IPR003954
Domain-

LIG3 CTDP1

4.76e-03238423.40.50.10190
DomainRRM_1

TIA1 TIAL1

4.76e-0323842SM00361
DomainEGF-like_dom

ATRN FRAS1 TENM1 LAMB2 C6

5.31e-03249845IPR000742
DomainKRAB

ZNF14 ZNF528 ZNF439 ZNF850 ZKSCAN5 ZNF443

5.52e-03358846PF01352
DomainBRCT

LIG3 CTDP1

6.06e-0326842PS50172
DomainIPT

MET PLXNB1

6.52e-0327842SM00429
DomainBRCT_dom

LIG3 CTDP1

7.00e-0328842IPR001357
DomainSPRY

TRIM41 BTN3A1 RYR2

7.09e-0387843SM00449
DomainEGF_LAM_2

ATRN LAMB2

8.01e-0330842PS50027
DomainEGF_LAM_1

ATRN LAMB2

8.01e-0330842PS01248
DomainTIG

MET PLXNB1

8.54e-0331842PF01833
DomainSema

MET PLXNB1

8.54e-0331842SM00630
DomainSemap_dom

MET PLXNB1

8.54e-0331842IPR001627
DomainSema

MET PLXNB1

8.54e-0331842PF01403
DomainSEMA

MET PLXNB1

8.54e-0331842PS51004
DomainSPRY

TRIM41 BTN3A1 RYR2

8.77e-0394843PF00622
DomainSPRY_dom

TRIM41 BTN3A1 RYR2

8.77e-0394843IPR003877
DomainGalactose-bd-like

LAMB2 PTPRU F5

8.77e-0394843IPR008979
PathwayREACTOME_SEMA4D_MEDIATED_INHIBITION_OF_CELL_ATTACHMENT_AND_MIGRATION

MET RRAS PLXNB1

5.40e-068663M27325
PathwayREACTOME_SEMA4D_MEDIATED_INHIBITION_OF_CELL_ATTACHMENT_AND_MIGRATION

MET RRAS PLXNB1

5.40e-068663MM15045
PathwayREACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING

MET RRAS PLXNB1

4.28e-0515663MM15037
PathwayREACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING

MET RRAS PLXNB1

1.85e-0424663M2243
Pubmed

Discovering human diabetes-risk gene function with genetics and physiological assays.

GLIS3 DGKB SIX3

1.21e-06986330242153
Pubmed

Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.

RRAS ZHX2 PLXNB1

4.10e-061386319805522
Pubmed

Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene.

PGK1 PGK2

6.04e-0628629023984
Pubmed

iCLIP predicts the dual splicing effects of TIA-RNA interactions.

TIA1 TIAL1

6.04e-06286221048981
Pubmed

Identification of chosen apoptotic (TIAR and TIA-1) markers expression in thyroid tissues from adolescents with immune and non-immune thyroid diseases.

TIA1 TIAL1

6.04e-06286220675271
Pubmed

Co-expression of plexin-B1 and Met in human breast and ovary tumours enhances the risk of progression.

MET PLXNB1

6.04e-06286219940359
Pubmed

TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAs.

TIA1 TIAL1

6.04e-06286211514562
Pubmed

Two isoforms of the T-cell intracellular antigen 1 (TIA-1) splicing factor display distinct splicing regulation activities. Control of TIA-1 isoform ratio by TIA-1-related protein.

TIA1 TIAL1

6.04e-06286217488725
Pubmed

Evolution of mammalian X-linked and autosomal Pgk and Pdh E1 alpha subunit genes.

PDHA1 PGK1

6.04e-0628628752009
Pubmed

Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.

PGK1 PGK2

6.04e-0628623453121
Pubmed

A factor stimulating transcription of the testis-specific Pgk-2 gene recognizes a sequence similar to the binding site for a transcription inhibitor of the somatic-type Pgk-1 gene.

PGK1 PGK2

6.04e-0628628441629
Pubmed

The stress granule component TIA-1 binds tick-borne encephalitis virus RNA and is recruited to perinuclear sites of viral replication to inhibit viral translation.

TIA1 TIAL1

6.04e-06286224696465
Pubmed

Transcription switch of two phosphoglycerate kinase genes during spermatogenesis as determined with mouse testis sections in situ.

PGK1 PGK2

6.04e-0628622298243
Pubmed

T-cell intracellular antigen (TIA)-proteins deficiency in murine embryonic fibroblasts alters cell cycle progression and induces autophagy.

TIA1 TIAL1

6.04e-06286224086455
Pubmed

Genetic mapping and allelic loss analysis in mouse thymic lymphomas of Helios and Aiolos belonging to the Ikaros gene family.

IKZF3 IKZF2

6.04e-06286211173542
Pubmed

Selective activation of testis-specific genes in cultured rat spermatogenic cells.

PGK1 PGK2

6.04e-0628622166582
Pubmed

Genome-wide profiling reveals a role for T-cell intracellular antigens TIA1 and TIAR in the control of translational specificity in HeLa cells.

TIA1 TIAL1

6.04e-06286224927121
Pubmed

Splicing of the large intron present in the nonstructural gene of minute virus of mice is governed by TIA-1/TIAR binding downstream of the nonconsensus donor.

TIA1 TIAL1

6.04e-06286219339348
Pubmed

Plexin B1 suppresses c-Met in melanoma: a role for plexin B1 as a tumor-suppressor protein through regulation of c-Met.

MET PLXNB1

6.04e-06286220164843
Pubmed

Structure, tissue distribution and genomic organization of the murine RRM-type RNA binding proteins TIA-1 and TIAR.

TIA1 TIAL1

6.04e-0628628871565
Pubmed

Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme.

PGK1 PGK2

6.04e-0628625009693
Pubmed

Identification of the sequence determinants mediating the nucleo-cytoplasmic shuttling of TIAR and TIA-1 RNA-binding proteins.

TIA1 TIAL1

6.04e-06286216278295
Pubmed

The family of mouse phosphoglycerate kinase genes and pseudogenes.

PGK1 PGK2

6.04e-0628622829366
Pubmed

Characterization of phosphoglycerate kinase from human spermatozoa.

PGK1 PGK2

6.04e-0628621278465
Pubmed

Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities.

TIA1 TIAL1

6.04e-0628628576255
Pubmed

Differential appearance of DNase I-hypersensitive sites correlates with differential transcription of Pgk genes during spermatogenesis in the mouse.

PGK1 PGK2

6.04e-0628628662942
Pubmed

TIAR and TIA-1 mRNA-binding proteins co-aggregate under conditions of rapid oxygen decline and extreme hypoxia and suppress the HIF-1α pathway.

TIA1 TIAL1

6.04e-06286220980400
Pubmed

A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation.

TIA1 TIAL1

6.04e-06286218456862
Pubmed

Structure of the central RNA recognition motif of human TIA-1 at 1.95A resolution.

TIA1 TIAL1

6.04e-06286218201561
Pubmed

TIA-1 and TIAR interact with 5'-UTR of enterovirus 71 genome and facilitate viral replication.

TIA1 TIAL1

6.04e-06286226363455
Pubmed

TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha.

TIA1 TIAL1

6.04e-06286210921895
Pubmed

Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.

GLIS3 DGKB SIX3

1.61e-052086325187374
Pubmed

TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2.

TIA1 TIAL1

1.81e-05386219110540
Pubmed

TIA1 prevents skipping of a critical exon associated with spinal muscular atrophy.

TIA1 TIAL1

1.81e-05386221189287
Pubmed

Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene.

PGK1 PGK2

1.81e-0538621380672
Pubmed

RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth.

GPLD1 DGKB

1.81e-05386234944458
Pubmed

Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia.

IKZF3 IKZF2

1.81e-05386211937265
Pubmed

Tumor protein D52 expression is post-transcriptionally regulated by T-cell intercellular antigen (TIA) 1 and TIA-related protein via mRNA stability.

TIA1 TIAL1

1.81e-05386228298474
Pubmed

Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors.

IKZF3 IKZF2

1.81e-0538629560339
Pubmed

The genomic landscape of hypodiploid acute lymphoblastic leukemia.

IKZF3 IKZF2

1.81e-05386223334668
Pubmed

Analysis of Ikaros family splicing variants in human hematopoietic lineages.

IKZF3 IKZF2

1.81e-05386220432734
Pubmed

Expression patterns of Ikaros family members during positive selection and lineage commitment of human thymocytes.

IKZF3 IKZF2

1.81e-05386227502439
Pubmed

Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs.

TIA1 TIAL1

1.81e-05386215280467
Pubmed

Long-term reduction of T-cell intracellular antigens leads to increased beta-actin expression.

TIA1 TIAL1

1.81e-05386224766723
Pubmed

Sema4D induces angiogenesis through Met recruitment by Plexin B1.

MET PLXNB1

1.81e-05386215632204
Pubmed

HuR and TIA1/TIAL1 are involved in regulation of alternative splicing of SIRT1 pre-mRNA.

TIA1 TIAL1

1.81e-05386224566137
Pubmed

Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome.

LAMB2 RYR2

1.81e-05386231235574
Pubmed

An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response.

TIA1 TIAL1

1.81e-05386217349961
Pubmed

The RNA binding proteins TIA1 and TIAL1 promote Mcl1 mRNA translation to protect germinal center responses from apoptosis.

TIA1 TIAL1

1.81e-05386237474714
Pubmed

The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras.

RRAS PLXNB1

1.81e-05386215297673
Pubmed

The semaphorin 4D receptor controls invasive growth by coupling with Met.

MET PLXNB1

1.81e-05386212198496
Pubmed

Transactivation of Met signalling by semaphorin4D in human placenta: implications for the pathogenesis of preeclampsia.

MET PLXNB1

1.81e-05386229939944
Pubmed

Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma.

IKZF3 IKZF2

1.81e-05386218332232
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

ATRN MET PCYOX1L FAM234A PPT2 LAMB2 FBXW2 NUP93 HEPH

2.13e-0561386922268729
Pubmed

Differential expression of the immunosuppressive enzyme IL4I1 in human induced Aiolos+, but not natural Helios+, FOXP3+ Treg cells.

IKZF3 IKZF2

3.61e-05486225446972
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

FRAS1 LAMB2

3.61e-05486224101214
Pubmed

CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation.

GLIS3 PGK1

3.61e-05486238459513
Pubmed

Analysis of male meiotic "sex body" proteins during XY female meiosis provides new insights into their functions.

PDHA1 PGK1

3.61e-05486211072798
Pubmed

A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.

FRAS1 F5

3.61e-05486223703922
Pubmed

The splicing regulators TIA1 and TIAL1 are required for the expression of the DNA damage repair machinery during B cell lymphopoiesis.

TIA1 TIAL1

3.61e-05486236543128
Pubmed

Effect of cancer-associated mutations in the PlexinB1 gene.

MET PLXNB1

3.61e-05486222404908
Pubmed

Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase.

RPS6KA2 PAK5

3.61e-05486210521512
Pubmed

ErbB-2 and met reciprocally regulate cellular signaling via plexin-B1.

MET PLXNB1

3.61e-05486218025083
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ATRN MET ABCC3 PCYOX1L FRAS1 FAM234A GLG1 KIAA1549 LAMB2 CLSTN1 PLXNB1 SLC27A3

3.95e-051201861235696571
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

MET PCYOX1L FRAS1 FAM234A LAMB2

5.61e-0516486532409323
Pubmed

Structure and function of the intracellular region of the plexin-b1 transmembrane receptor.

RRAS PLXNB1

6.01e-05586219843518
Pubmed

BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival.

RPS6KA2 PAK5

6.01e-05586210837486
Pubmed

The proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein U.

TIA1 TIAL1

6.01e-05586212855701
Pubmed

Plexin-B3 is a functional receptor for semaphorin 5A.

MET PLXNB1

6.01e-05586215218527
Pubmed

Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

IKZF3 IKZF2

6.01e-05586210978333
Pubmed

Interplay between scatter factor receptors and B plexins controls invasive growth.

MET PLXNB1

6.01e-05586215184888
Pubmed

Neurexophilins form a conserved family of neuropeptide-like glycoproteins.

NXPH1 NXPH4

6.01e-0558629570794
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TIA1 ZFHX4 TIAL1 GLIS3 NUP93 ANAPC5

7.36e-0528286623667531
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

TENM1 PTPRU CLSTN1 PLXNB1

7.90e-059186428558017
Pubmed

KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility.

PGK1 PGK2

9.01e-05686222654668
Pubmed

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.

RPS6KA2 PAK5

9.01e-0568629381178
Pubmed

Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L leads to aberrant hypermethylation and postnatal lethality in mice.

DCAF12L1 PGK1

1.26e-04786230834655
Pubmed

Lsh, an epigenetic guardian of repetitive elements.

PGK1 PGK2

1.26e-04786215448183
Pubmed

Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155.

RPS6KA2 PAK5

1.26e-04786210880354
Pubmed

ORFless, intronless, and mutant transcription units in the mouse t complex responder (Tcr) locus.

RPS6KA2 TREX2

1.26e-04786210501965
Pubmed

Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit.

NXPH1 NXPH4

1.26e-0478629856994
Pubmed

p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling.

MET PLXNB1

1.68e-04886216188938
Pubmed

Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells.

MET PLXNB1

2.68e-041086212730235
Pubmed

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.

TIA1 TIAL1

2.68e-041086212388085
Pubmed

A systematic analysis of a deep mouse epididymal sperm proteome.

PGK1 PGK2

2.68e-041086223115268
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

IKZF3 IKZF2 ANAPC5 TRAPPC9

3.03e-0412986423022380
Pubmed

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.

ADAMTS6 CTDP1

3.28e-041186223212062
Pubmed

Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.

MPL PTPRU

3.28e-041186210721728
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

LIG3 PDHA1 GLG1 RPS6KA2 TRIM41 FIBP ANAPC5

3.61e-0453386725544563
Pubmed

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.

GLIS3 DGKB

3.93e-041286220419449
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

GPLD1 ATRN C6 F5 PLXNB1

4.53e-0425786516335952
Pubmed

Mapping of loci and translocation breakpoints in Xq13: isolation of a conserved locus that maps close to CCG1 in human and mouse.

PDHA1 PGK1

4.63e-04138628012115
Pubmed

The intracellular domain of teneurin-1 induces the activity of microphthalmia-associated transcription factor (MITF) by binding to transcriptional repressor HINT1.

TENM1 FIBP

4.63e-041386225648896
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ALMS1 TENM1 KIAA1549 ANKLE2 FAM135A

5.03e-0426386534702444
Pubmed

A molecular dissection of the repression circuitry of Ikaros.

IKZF3 IKZF2

5.39e-041486212015313
Pubmed

Ubiquitin-dependent degradation of CDK2 drives the therapeutic differentiation of AML by targeting PRDX2.

ZBTB20 FBXW2

5.39e-041486229720484
Pubmed

An oocyte-specific ELAVL2 isoform is a translational repressor ablated from meiotically competent antral oocytes.

TIA1 TIAL1

5.39e-041486224553115
Pubmed

Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing.

ATRN ZHX2

6.21e-041586219436707
Pubmed

Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.

TIA1 TIAL1

7.09e-041686221436445
Pubmed

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.

PDHA1 PGK1

8.02e-041786219571810
InteractionSDF2L1 interactions

ATRN MET FRAS1 GLG1 LAMB2 PTPRU CLSTN1 ANKLE2 NXPH4

7.07e-06322839int:SDF2L1
InteractionGPIHBP1 interactions

MET FRAS1 LAMB2 PTPRU CLSTN1 NXPH4

1.84e-05133836int:GPIHBP1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF14 ZNF23 IKZF3 IKZF2 ZBTB20 GLIS3 ZNF528 ZHX2 ZNF439 ZNF850 ZKSCAN5 ZNF443

1.57e-06718561228
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 ZHX2

9.64e-0415562529
CoexpressionCARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_UP

TBC1D16 ZNF14 PCYOX1L FRAS1 HTR1F TIA1 ADAMTS6 PIK3C2B GLG1 KIAA1549 NUP93 CLSTN1 TLCD5

6.52e-068918613M45033
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZFHX4 OTOGL TENM1 DGKB CSMD3 RYR2

6.98e-081848672cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZFHX4 OTOGL TENM1 DGKB CSMD3 RYR2

6.98e-08184867ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZFHX4 OTOGL TENM1 DGKB CSMD3 RYR2

6.98e-081848672b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MET ADAMTS6 PIK3C2B RPS6KA2 LAMB2 F5 FAM135A

1.23e-07200867ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX4 GLIS3 LAMB2 ZHX2 HEPH PLXNB1

1.98e-0619286643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX4 GLIS3 LAMB2 ZHX2 HEPH PLXNB1

2.04e-06193866b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX4 GLIS3 LAMB2 ZHX2 HEPH PLXNB1

2.04e-0619386640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PPT2 ADAMTS6 PIK3C2B RPS6KA2 F5 FAM135A

2.50e-06200866b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Interneuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

MET ZBTB20 NXPH1 ARRDC3

7.24e-0664864fefabdf8d72a8f3caf78eb79d759edb475bdb2ad
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 OTOGL NEK10 ANKRD60 SIGLEC15

7.99e-061418654aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 OTOGL NEK10 ANKRD60 SIGLEC15

7.99e-06141865e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 OTOGL NEK10 ANKRD60 SIGLEC15

8.27e-06142865759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZFHX4 PAK5 DGKB RYR2

1.47e-05160865c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZFHX4 PAK5 DGKB RYR2

1.47e-0516086525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 OTOGL TENM1 CSMD3 F5

1.57e-05162865bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IKZF2 ZFHX4 ZNF528 SIX3 ZNF443

1.76e-051668659fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPLD1 TIA1 PIK3C2B NEK10 FASTKD3

1.76e-051668653b750d4023a0a09d86113aae5a97d84391f7b482
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MET HTR1F OTOGL GLIS3 KIAA1549

1.92e-05169865319cba07263bf41fcbcbfecd117f91b729394241
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 OTOGL C6 CSMD3 RYR2

1.92e-0516986512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 RPS6KA2 ANKRD60 KIAA1549 FAM135A

2.21e-05174865f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCC3 FRAS1 TENM1 GLIS3 KIAA1549

2.81e-051838656878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS6 PIK3C2B TM6SF1 F5 FAM135A

3.04e-051868652d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH3 ADAMTS6 NXPH1 SIX3 CSMD3

3.04e-05186865bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

MET ADAMTS6 PIK3C2B TM6SF1 FAM135A

3.12e-0518786540ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ATRN ADAMTS6 PIK3C2B ZNF528 BTN3A1

3.28e-05189865bccb3481ffed597c845fe860da658505316105b5
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS6 PIK3C2B TM6SF1 F5 FAM135A

3.28e-05189865c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX4 LAMB2 ZHX2 HEPH PLXNB1

3.36e-051908655c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB20 ZFHX4 ZHX2 HEPH PLXNB1

3.36e-051908652de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MET ABCC3 FRAS1 IKZF2 NEK10

3.45e-0519186560ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB20 ZFHX4 ZHX2 HEPH PLXNB1

3.45e-05191865f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MET ABCC3 FRAS1 ZBTB20 FAM135A

3.71e-051948657002937e8903e037332a215d00fbc7c7843b33f2
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ABCC3 FRAS1 UGT1A6 CLSTN1 PLXNB1

3.90e-051968653b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IKZF2 ZBTB20 NEK10 TENM1 BBS2

4.00e-05197865e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HTR1F ADAMTS6 OTOGL DGKB RYR2

4.00e-05197865ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZBTB20 RPS6KA2 NXPH1 TENM1 ZHX2

4.29e-05200865f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

ZBTB20 ZFHX4 ZHX2 HEPH PLXNB1

4.29e-05200865e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZBTB20 RPS6KA2 NXPH1 TENM1 ZHX2

4.29e-0520086570a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS6 PIK3C2B RPS6KA2 F5 FAM135A

4.29e-0520086577ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

ADAMTS6 PIK3C2B TM6SF1 F5 FAM135A

4.29e-0520086565b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZBTB20 RPS6KA2 NXPH1 TENM1 ZHX2

4.29e-052008651639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

PIK3C2B RPS6KA2 LAMB2 F5 FAM135A

4.29e-05200865b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MPP3 IKZF2 ADAMTS6 ZNF443

1.01e-04125864e112787b05d8147093357c9861877f6620b9e271
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MPP3 IKZF2 ADAMTS6 ZNF443

1.01e-0412586434d5be868c9728cc4f9ce0d65acf0e50171d2587
ToppCellT_cells-Treg_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

IKZF2 F5 PGK2 TLCD5

1.48e-0413886435880e23ef317862891b54ac6a2265ca03b1d12a
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Met|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MET TBATA PAK5 NXPH1

1.79e-041458648abbc781f5f69f039617c29a5589d7b6950c2c40
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 OTOGL TENM1 CSMD3

1.79e-0414586496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MPL IKZF3 PIK3C2B KIAA1549

2.09e-04151864bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 HTR1F UGT1A6 PLXNB1

2.14e-0415286472499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCellfrontal_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

TBATA HTR1F ZFHX4 TENM1

2.14e-04152864f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCellChildren_(3_yrs)-Immune-mast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF14 IKZF3 KIAA1549 ZNF439

2.20e-04153864d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF23 ZBTB20 NEK10 LAMB2

2.31e-0415586496c48d835725eac1bc7926f4cddecb67c29b7d7c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC3 NEK10 PTPRU RYR2

2.49e-041588647f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BCO2 KIAA1549 LAMB2 TLR8

2.49e-0415886474aa4f75307575ac3b2b1aa9f727753692f88742
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 TREX2 F5 TLCD5

2.55e-04159864ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 TREX2 F5 TLCD5

2.55e-04159864b05fda31b77536a1878f55d3199563b53f9420b2
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

BCO2 KIAA1549 LAMB2 TLR8

2.67e-0416186458381131e651744b5141b202f9d6063f55432db5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH3 TBATA HTR1F PAK5

2.73e-0416286458da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH3 TBATA HTR1F PTPRU

2.73e-041628644d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH3 TBATA HTR1F PAK5

2.80e-04163864b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MET ABCC3 TENM1 GLIS3

2.86e-041648641cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 RPS6KA2 TM6SF1 RYR2

3.00e-04166864ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MYH3 BCO2 NEK10 C6

3.00e-041668644b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

TBC1D16 ABCC3 CYFIP1 LAMB2

3.14e-041688648ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC3 HTR1F ADAMTS6 OTOGL

3.14e-041688641d58731a481ecac84c15affa84f8041dd67d944c
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH3 NXPH1 NXPH4 TLCD5

3.21e-04169864a388e53deac861a185c31e9cceddae7bcb344700
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC3 HTR1F ADAMTS6 OTOGL

3.28e-0417086449fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MET HTR1F OTOGL GLIS3

3.28e-041708643174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MET HTR1F OTOGL GLIS3

3.28e-041708645de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC3 HTR1F ADAMTS6 OTOGL

3.36e-041718649d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

IKZF3 ADAMTS6 TM6SF1 BTN3A1

3.43e-04172864c477008444d2d71071177807870d7455e90c2fad
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 ZNF23 TMEM62 ANKLE2

3.43e-04172864356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 ZNF23 TMEM62 ANKLE2

3.43e-0417286446fadeee483fdf8402df92ec98575a09c6c15b16
ToppCellImmune-mast_cell|World / Lineage, Cell type, age group and donor

MPL IKZF3 HTR1F KIAA1549

3.43e-041728646e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 ZNF23 TMEM62 ANKLE2

3.43e-04172864438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MET HTR1F OTOGL GLIS3

3.51e-041738649a2d42f8d9cb834856522661d524abb91c4637c5
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

MET IKZF2 ZNF850 TLCD5

3.58e-04174864390bd41ef114464f3db3e0cac4e67fe7571b4c23
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

PCYOX1L NEK10 NXPH4 RYR2

3.58e-04174864e324320b52c904496e26fcecfa179b3431729ec0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MET HTR1F OTOGL KIAA1549

3.58e-04174864b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TBC1D16 PCYOX1L BCO2 TRIM41

3.58e-04174864e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB20 LAMB2 FAM135A NXPH4

3.58e-04174864cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBATA ALMS1 TENM1 RYR2

3.66e-0417586465571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA2 TENM1 GLIS3 PGK2

3.66e-04175864f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZFHX4 CSMD3 RYR2

3.66e-04175864887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB20 ARRDC3 TLR8 RYR2

3.74e-04176864749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IKZF3 ZBTB20 PIK3C2B

3.74e-04176864741fdacb33d49b030a797a6099fdea0949a22e75
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB20 BCO2 DGKB CSMD3

3.74e-041768646c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

DAGLB ZBTB20 BCO2 GLG1

3.82e-0417786482fdd6185b368f54f03de389427cbe3071d21a99
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALMS1 DCAF12L1 RPS6KA2 LAMB2

3.82e-041778648ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPL CSMD3 F5 HEPH

3.91e-04178864f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB20 BCO2 DGKB CSMD3

3.91e-0417886451d2188406f04329311b2efd1108fc36617a860e
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MET FRAS1 GLIS3 PLXNB1

3.91e-04178864fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PIK3C2B RPS6KA2 TM6SF1

3.91e-041788645f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MET ADAMTS6 PIK3C2B TM6SF1

3.99e-041798642a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB20 ZFHX4 NXPH1 ZHX2

4.25e-041828648a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB20 ZFHX4 NXPH1 ZHX2

4.25e-041828643cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB20 ZFHX4 NXPH1 ZHX2

4.25e-041828645d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB20 ZFHX4 NXPH1 ZHX2

4.25e-04182864e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF3 ZBTB20 ADAMTS6 NXPH4

4.34e-04183864ffa831f67ed005f05d1b80ebc707e046fc08e22f
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN ABCC3 FAM234A IKZF2

4.43e-04184864382b1e90b3f437af596750669c0465a169d97095
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZBTB20 ZFHX4 NXPH1 ZHX2

4.52e-04185864efc5d564f8793c751ba640aef60f761e4b081d3f
DrugSTOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A

MPP3 MET ABCC3 LIG3 ZHX2 ANAPC5 ZKSCAN5 BTN3A1

8.12e-071978686561_DN
DrugFillalbin [4540-25-4]; Up 200; 13.8uM; PC3; HT_HG-U133A

MPP3 GPLD1 ABCC3 HTR1F ARSD BTN3A1 TRAPPC9

8.91e-061948674092_UP
Drug3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A

MET ZBTB20 TENM1 SIX3 FAM135A BTN3A1 HEPH

9.84e-061978676367_UP
Drug4-Arsono-2-hydroxybutanoic acid

PGK1 PGK2

1.41e-052862CID000135804
Diseaseserum gamma-glutamyl transferase measurement

ATRN MET IKZF3 IKZF2 ICE2 UGT1A6 GLIS3 CSMD3 ANAPC5 RYR2

2.97e-049148510EFO_0004532
Diseasemacrovascular complications of diabetes

RPS6KA2 F5

3.64e-0410852EFO_0010977
DiseaseMetastatic melanoma

NEK10 RPS6KA2 PAK5

5.15e-0454853C0278883
Diseasediastolic blood pressure, systolic blood pressure

TBC1D16 MET LIG3 PPT2 ALMS1 NEK10 TRAPPC9 RYR2

7.02e-04670858EFO_0006335, EFO_0006336
Diseaseglucose measurement

FAM234A ZBTB20 PDHA1 GLIS3 DGKB SIX3

8.15e-04380856EFO_0004468
DiseaseX-21441 measurement

ABCC3 UGT1A6

1.08e-0317852EFO_0800814
Disease1-Methylhistidine measurement

ALMS1 OTOGL

1.08e-0317852EFO_0021543
Diseasefasting blood glucose measurement

ZFHX4 PAK5 GLIS3 DGKB SIX3

1.46e-03287855EFO_0004465
Diseasecoagulation factor V measurement

PAK5 F5

1.51e-0320852EFO_0008087
Diseasehormone measurement

UGT1A6 ZKSCAN5 RYR2

1.86e-0384853EFO_0004730
DiseaseCerebral Astrocytoma

MET KIAA1549

2.36e-0325852C0750935
DiseaseIntracranial Astrocytoma

MET KIAA1549

2.36e-0325852C0750936
DiseasePilocytic Astrocytoma

MET KIAA1549

2.36e-0325852C0334583
DiseaseAstrocytoma

MET KIAA1549

2.36e-0325852C0004114
DiseaseJuvenile Pilocytic Astrocytoma

MET KIAA1549

2.36e-0325852C0280783
DiseaseDiffuse Astrocytoma

MET KIAA1549

2.36e-0325852C0280785
DiseaseGrade I Astrocytoma

MET KIAA1549

2.36e-0325852C1704230
DiseaseSubependymal Giant Cell Astrocytoma

MET KIAA1549

2.36e-0325852C0205768
DiseaseMixed oligoastrocytoma

MET KIAA1549

2.36e-0325852C0547065
DiseaseChildhood Cerebral Astrocytoma

MET KIAA1549

2.36e-0325852C0338070
DiseaseGemistocytic astrocytoma

MET KIAA1549

2.55e-0326852C0334581
DiseaseProtoplasmic astrocytoma

MET KIAA1549

2.55e-0326852C0334580
DiseaseFibrillary Astrocytoma

MET KIAA1549

2.55e-0326852C0334582
DiseaseAdenocarcinoma of large intestine

MET RPS6KA2 PAK5

2.72e-0396853C1319315
DiseaseAnaplastic astrocytoma

MET KIAA1549

2.75e-0327852C0334579

Protein segments in the cluster

PeptideGeneStartEntry
YSAVRRDGSFHYVHS

TMEM62

161

Q0P6H9
ESGFLLHVTRTGAHY

FAM234A

261

Q9H0X4
ELHVFTFGSRLYAHT

CTDP1

241

Q9Y5B0
RLSSFYHHEAGVTAL

ANKLE2

116

Q86XL3
GAEARSAHEFLFHYC

ARSD

446

P51689
HFVTDSNHRYRGFSA

CSMD3

326

Q7Z407
LAFRSDGSVSYTGFH

CSMD3

1676

Q7Z407
ISFYNAVDGSHIHTF

BTN3A1

471

O00481
HDHIVSTIYSTFGAF

HTR1F

176

P30939
STSHSHVEDLLFFYR

ALMS1

666

Q8TCU4
FVALYVASHRGHFDA

ANKRD60

221

Q9BZ19
SLSGVHHFARAASEF

CLSTN1

656

O94985
FLHFIRSHSATAVDF

BCO2

6

Q9BYV7
GFHTIHSGRHEYAFS

ARRDC3

101

Q96B67
LYDHSHCGVSDFTRS

ADAMTS6

201

Q9UKP5
ITFFDEYHSGHIDRA

NUP93

696

Q8N1F7
HVNGTFSVYFRHNSS

NXPH4

131

O95158
YVNDAFGTAHRAHSS

PGK2

161

P07205
ADLFYSFHGLVHGRA

ABCC3

86

O15438
AYAESASHFHTFRSA

KIAA1549

221

Q9HCM3
DVFSSTHSLLHYFDR

ANAPC5

266

Q9UJX4
DFARFSADYHSHLDS

PAK5

191

Q9P286
HRESFFYTHLINFSE

CYFIP1

596

Q7L576
FSFYVSDGTSRSEIH

FRAS1

1931

Q86XX4
ATSGYALLHFFSDAA

ATRN

221

O75882
SFIIADSFLHHAYRF

FAM135A

226

Q9P2D6
HYESGAASFHSLSLH

PCYOX1L

76

Q8NBM8
LAVGRLSEYSHHFVS

PLXNB1

206

O43157
LSEYSHHFVSAFARG

PLXNB1

211

O43157
HHFVSAFARGASAYF

PLXNB1

216

O43157
NFFTADYHLLHRSSG

NEK10

1096

Q6ZWH5
FLGAYDSIRHAHSQS

LAMB2

1326

P55268
YVNDAFGTAHRAHSS

PGK1

161

P00558
VHKNGDHFSYFSRSL

LIG3

516

P49916
RYEFSSHIVRGEHTF

IKZF2

511

Q9UKS7
GYSARHEVRQFHFTA

PTPRU

1036

Q92729
HFARSLAFTVYATHR

PIK3C2B

626

O00750
VVHGLFDSSYSFRHL

PPT2

41

Q9UMR5
LSSDDFHLDRHLYFA

GLG1

301

Q92896
HSNSSFYVGHIDAFT

ICE2

801

Q659A1
HLKAFVGYRSSTQFH

BBS2

456

Q9BXC9
RIFDDFGTHYFTSGS

C6

356

P13671
TTGLQYRDFIHVSFH

DAGLB

336

Q8NCG7
FDVFHRAFSTHSGIT

GLIS3

716

Q8NEA6
YFSIGVDASIAHRFH

DGKB

586

Q9Y6T7
YAVGSHSHVSFLDLR

DCAF12L1

321

Q5VU92
HFRGHTGAVFSVDYN

FBXW2

221

Q9UKT8
GYRSHDRYEFSSHIA

IKZF3

486

Q9UKT9
HVYSSAAHFADVAGR

RYR2

506

Q92736
VGDSHFTTFDGRHYS

OTOGL

486

Q3ZCN5
ASAAFIDRHYGHLVD

MPP3

536

Q13368
YSASVHSLDGFRHQA

FIBP

331

O43427
FSTFIGEHYVHVNAT

MET

1341

P08581
GFYNAETLAHVHTFS

TRIM41

591

Q8WV44
SEASVYLFRFHGASG

SIGLEC15

246

Q6ZMC9
YLFRFHGASGASTVA

SIGLEC15

251

Q6ZMC9
FTGHSFIYGKRHEDT

F5

626

P12259
IVDHGNGTFSVYFRH

NXPH1

141

P58417
RVLEAFIYFGHHDTF

FASTKD3

336

Q14CZ7
TIHFHAESFLYRNGE

HEPH

1001

Q9BQS7
AVVAFHTGNFRDLYH

SIX3

136

O95343
TYCFGRLSHHSFFSR

TBATA

66

Q96M53
VSFLHHSDYGFTISR

TENM1

906

Q9UKZ4
AHFSLIHYAGTVDYS

MYH3

576

P11055
HAHSSGYFITQDSAF

INIP

76

Q9NRY2
LSYNSHYFRIAGVTH

TLR8

561

Q9NR97
HYHSFTGDVVDFLFV

TLCD5

151

Q6ZRR5
SFGYIRSFVTHAVHD

ZFHX4

286

Q86UP3
TDHLITAYRAHGFTF

PDHA1

111

P08559
HTFLIHGSRRFSYSE

SLC27A3

81

Q5K4L6
ASRESQYKVFHFHHG

TBC1D16

326

Q8TBP0
GAIDFHGSYSEAHSA

GPLD1

146

P80108
QDHASSQGFFYHSRA

MPL

306

P40238
SGERSFYSGAVVSHH

ZBTB20

256

Q9HC78
LAIAASRHGRTYHAY

ZHX2

511

Q9Y6X8
RGKAFSYHNSFQTHE

ZNF443

146

Q9Y2A4
FREFSDLTAHFLIHS

ZNF528

446

Q3MIS6
TGDFFLHIRFHEDST

TRAPPC9

1111

Q96Q05
GFSFSSDYIIHQTVH

ZNF23

596

P17027
RAFITHAGSHGVYES

UGT1A6

366

P19224
FHRYFRAEPSAAHSA

TREX2

176

Q9BQ50
EASAFGASHHVAYFE

RRAS

156

P10301
GYSFVRFSTHESAAH

TIAL1

241

Q01085
YSFVRFNSHESAAHA

TIA1

251

P31483
FFYASGLSRHQSVHT

ZNF850

1046

A8MQ14
FGYSSDLIQHYRTHT

ZKSCAN5

726

Q9Y2L8
SHIGASLHARTAYVY

TM6SF1

311

Q9BZW5
FFYSASFRAHVIIHT

ZNF14

316

P17017
FTRSGSFRYHERTHT

ZNF439

391

Q8NDP4
SANAHHLFRGFSFVA

RPS6KA2

366

Q15349