Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PTPN23	1.69e-07	103	79	7	GO:0004725
GeneOntologyMolecularFunction	phosphoprotein phosphatase activity	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PTPN23	9.93e-06	189	79	7	GO:0004721
GeneOntologyMolecularFunction	phosphatase activity	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PLPPR4 PTPN23	1.78e-05	287	79	8	GO:0016791
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PLPPR4 PTPN23 PLD6	2.14e-05	386	79	9	GO:0042578
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRA PTPRC PTPRH	3.89e-05	17	79	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRA PTPRC PTPRH	3.89e-05	17	79	3	GO:0019198
GeneOntologyBiologicalProcess	dephosphorylation	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PLPPR4 PTPN23	4.54e-05	347	77	8	GO:0016311
GeneOntologyBiologicalProcess	protein dephosphorylation	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PTPN23	4.80e-05	256	77	7	GO:0006470
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	FLNA MAP7D1 KIF19 TOGARAM1 NCKAP5 SRGAP2 MTCL1 PRC1 MAP10 DNAH5 WDR47	7.13e-05	720	77	11	GO:0000226
Domain	PTPc	PTPN2 PTPN13 PTPRA PTPRC PTPRH PTPN23	7.69e-09	36	78	6	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPN2 PTPN13 PTPRA PTPRC PTPRH PTPN23	1.28e-08	39	78	6	PS50055
Domain	PTPase_domain	PTPN2 PTPN13 PTPRA PTPRC PTPRH PTPN23	1.75e-08	41	78	6	IPR000242
Domain	Y_phosphatase	PTPN2 PTPN13 PTPRA PTPRC PTPRH PTPN23	1.75e-08	41	78	6	PF00102
Domain	TYR_PHOSPHATASE_1	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PTPN23	6.94e-08	86	78	7	PS00383
Domain	TYR_PHOSPHATASE_2	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PTPN23	7.53e-08	87	78	7	PS50056
Domain	TYR_PHOSPHATASE_dom	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH PTPN23	7.53e-08	87	78	7	IPR000387
Domain	Tyr_Pase_AS	PTPN2 MTMR4 PTPRA PTPRC PTPRH PTPN23	5.95e-07	73	78	6	IPR016130
Domain	-	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPN23	2.34e-06	92	78	6	3.90.190.10
Domain	Prot-tyrosine_phosphatase-like	PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPN23	3.59e-06	99	78	6	IPR029021
Domain	PTPc_motif	PTPN2 PTPN13 PTPRA PTPRC PTPN23	4.68e-06	59	78	5	SM00404
Domain	Tyr_Pase_cat	PTPN2 PTPN13 PTPRA PTPRC PTPN23	4.68e-06	59	78	5	IPR003595
Domain	ASX_HYDROXYL	SCUBE2 CLEC14A FAT3 EGFL7	8.15e-04	100	78	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SCUBE2 CLEC14A FAT3 EGFL7	1.01e-03	106	78	4	IPR000152
Pathway	REACTOME_INTERLEUKIN_37_SIGNALING	PTPN2 PTPN13 PTPN23	5.67e-05	21	51	3	M27873
Pubmed	Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor.	PTPN2 PTPN13 PTPRH	1.01e-06	9	81	3	12907755
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TGIF1 FLNA PTPN13 PTPRC KLHDC3 RSL1D1 PTPN23 SALL4 TMEM131 SRGAP2 ZCCHC2 HERC1 SRCAP	1.29e-06	1084	81	13	11544199
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FLNA DSP RSL1D1 FAT3 HERC1 DNAH5 NKRF	1.30e-06	234	81	7	36243803
Pubmed	Expression and functional analysis of Tgif during mouse midline development.	TGIF1 PAX7 FOXA2	1.44e-06	10	81	3	16284942
Pubmed	Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice.	PLD6 DNMT3L	5.36e-06	2	81	2	28749988
Pubmed	Protein tyrosine phosphatase nonreceptor type 2 regulates autophagosome formation in human intestinal cells.	PTPN2 ATG16L1	5.36e-06	2	81	2	21987459
Pubmed	Differential function of PTPalpha and PTPalpha Y789F in T cells and regulation of PTPalpha phosphorylation at Tyr-789 by CD45.	PTPRA PTPRC	5.36e-06	2	81	2	17507376
Pubmed	Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.	PTPN2 PTPRA PTPRC	6.67e-06	16	81	3	8875997
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	UIMC1 ATP6V1A FLNA PTPN13 DSP RSL1D1 PTPN23 SRGAP2 SRCAP CIC NKRF	1.08e-05	934	81	11	33916271
Pubmed	Consequences of increased CD45RA and RC isoforms for TCR signaling and peripheral T cell deficiency resulting from heterogeneous nuclear ribonucleoprotein L-like mutation.	PTPRA PTPRC	1.60e-05	3	81	2	20505149
Pubmed	An increase in synaptic NMDA receptors in the insular cortex contributes to neuropathic pain.	GRIN2B ADCY8	1.60e-05	3	81	2	23674822
Pubmed	Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn.	PTPRA PTPRC	1.60e-05	3	81	2	9535845
Pubmed	Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.	TGIF1 PAX7 FOXA2	1.82e-05	22	81	3	22383895
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	FLNA COL6A2 SLC41A3 WDR81 NCKAP5 SRGAP2 SRCAP	2.28e-05	363	81	7	14691545
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	USP31 PTPN2 MTMR4 PTPN13 PTPRA PTPRC PTPRH DSP PTPN23 HERC1 CIC	3.14e-05	1049	81	11	27880917
Pubmed	Pax7 is necessary and sufficient for the myogenic specification of CD45+:Sca1+ stem cells from injured muscle.	PTPRC PAX7	3.20e-05	4	81	2	15138500
Pubmed	Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains.	PTPRA PTPRC	3.20e-05	4	81	2	8759740
Pubmed	Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.	CLEC14A PAX7	3.20e-05	4	81	2	31852888
Pubmed	Gene Polymorphisms of NOD2, IL23R, PTPN2 and ATG16L1 in Patients with Crohn's Disease: On the Way to Personalized Medicine?	PTPN2 ATG16L1	3.20e-05	4	81	2	34198814
Pubmed	Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M.	PAX7 OSMR	3.20e-05	4	81	2	29670077
Pubmed	Lineage- and differentiation stage-specific expression of LSM-1 (LPAP), a possible substrate for CD45, in human hematopoietic cells.	PTPRA PTPRC	3.20e-05	4	81	2	8980254
Pubmed	Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB.	REL NKRF	5.33e-05	5	81	2	10562553
Pubmed	CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells.	PTPN2 PTPRC	5.33e-05	5	81	2	27841348
Pubmed	Reduced NMDA receptor tyrosine phosphorylation in PTPalpha-deficient mouse synaptosomes is accompanied by inhibition of four src family kinases and Pyk2: an upstream role for PTPalpha in NMDA receptor regulation.	PTPRA GRIN2B	5.33e-05	5	81	2	16899073
Pubmed	Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.	PTPRA PTPRC	5.33e-05	5	81	2	2169617
Pubmed	Diagnostic utility of CD117, CD133, SALL4, OCT4, TCL1 and glypican-3 in malignant germ cell tumors of the ovary.	PROM1 SALL4	7.99e-05	6	81	2	22448662
Pubmed	Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.	PTPRA BCAR3	1.12e-04	7	81	2	22801373
Pubmed	Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.	PTPRA PTPRC	1.12e-04	7	81	2	1454056
Pubmed	Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.	PTPRA PTPRC	1.12e-04	7	81	2	12376545
Pubmed	Endothelial cells within embryonic skeletal muscles: a potential source of myogenic progenitors.	PTPRC PAX7	1.12e-04	7	81	2	15530859
Pubmed	Restriction of BMP4 activity domains in the developing neural tube of the mouse embryo.	PAX7 FOXA2	1.12e-04	7	81	2	15218525
Pubmed	Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.	PTPRA PTPRC	1.12e-04	7	81	2	15978577
Pubmed	Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification.	PTPRA PTPRC	1.12e-04	7	81	2	1932742
Pubmed	WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.	ATG16L1 HERC1 WDR47	1.13e-04	40	81	3	29078390
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	FLNA DSP RSL1D1 MTCL1 PRC1	1.35e-04	210	81	5	16565220
Pubmed	Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase.	PTPRC PAX7	1.49e-04	8	81	2	28592560
Pubmed	HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity.	FLNA DSP	1.49e-04	8	81	2	28827800
Pubmed	TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system.	PAX7 FOXA2	1.49e-04	8	81	2	36669111
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PTPN13 PTPRA DSP RSL1D1 ADGRB3 TRIM8 TMEM131 NCKAP5 SRGAP2 GRIN2B WDR47	1.90e-04	1285	81	11	35914814
Pubmed	Loss of Asb2 Impairs Cardiomyocyte Differentiation and Leads to Congenital Double Outlet Right Ventricle.	FLNA FOXA2	1.91e-04	9	81	2	32179481
Pubmed	Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused.	PAX7 FOXA2	1.91e-04	9	81	2	16155214
Pubmed	Protein kinase A deficiency causes axially localized neural tube defects in mice.	PAX7 FOXA2	1.91e-04	9	81	2	11886853
Pubmed	The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.	PAX7 FOXA2	1.91e-04	9	81	2	16647304
Pubmed	The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration.	PTPRC FOXA2	1.91e-04	9	81	2	30923168
Pubmed	TRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitination.	FLNA RSL1D1	2.38e-04	10	81	2	36229750
Pubmed	Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched.	PAX7 FOXA2	2.38e-04	10	81	2	12372301
Pubmed	Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.	FLNA ATG16L1	2.38e-04	10	81	2	23434281
Pubmed	FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.	PTPRC FCRL6	2.38e-04	10	81	2	17213291
Pubmed	Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.	PAX7 FOXA2	2.38e-04	10	81	2	12812795
Pubmed	Gli1 can rescue the in vivo function of Gli2.	PAX7 FOXA2	2.38e-04	10	81	2	11748151
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	TGIF1 ATP6V1A PTPRA SLC41A3 OSMR MDK PPID CIC NKRF DNMT3L	2.81e-04	1124	81	10	21900206
Pubmed	A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.	PTPN13 PTPRA	2.91e-04	11	81	2	7832766
Pubmed	Mouse Rab23 regulates hedgehog signaling from smoothened to Gli proteins.	PAX7 FOXA2	2.91e-04	11	81	2	16364285
Pubmed	Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l.	TGIF1 KIF19	2.91e-04	11	81	2	27956704
Pubmed	Identification of novel SHPS-1-associated proteins and their roles in regulation of insulin-like growth factor-dependent responses in vascular smooth muscle cells.	FLNA COL6A2 PTPRA	3.09e-04	56	81	3	19299420
Pubmed	IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.	PAX7 FOXA2	3.48e-04	12	81	2	22595669
Pubmed	Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand.	PAX7 FOXA2	3.48e-04	12	81	2	15576405
Pubmed	PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube.	PAX7 FOXA2	3.48e-04	12	81	2	21761479
Pubmed	Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway.	PAX7 FOXA2	3.48e-04	12	81	2	11449277
Pubmed	Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo.	PAX7 FOXA2	3.48e-04	12	81	2	21337666
Pubmed	PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates.	PAX7 FOXA2	3.48e-04	12	81	2	15229603
Pubmed	Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo.	PAX7 FOXA2	3.48e-04	12	81	2	21912524
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAP7D1 PLPPR4 ADGRB3 WDR81 SRGAP2 MTCL1 GRIN2B MDK WDR47	4.04e-04	963	81	9	28671696
Pubmed	T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor.	PAX7 FOXA2	4.11e-04	13	81	2	25760946
Pubmed	Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.	PROM1 DNAH5	4.11e-04	13	81	2	35942101
Pubmed	Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1.	PAX7 FOXA2	4.11e-04	13	81	2	15576403
Pubmed	Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.	PAX7 FOXA2	4.11e-04	13	81	2	9636069
Pubmed	SHH E176/E177-Zn2+ conformation is required for signaling at endogenous sites.	PAX7 FOXA2	4.11e-04	13	81	2	28263766
Pubmed	Tulp3 is a critical repressor of mouse hedgehog signaling.	PAX7 FOXA2	4.11e-04	13	81	2	19334287
Pubmed	Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis.	PAX7 FOXA2	4.11e-04	13	81	2	26965371
Pubmed	Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel-Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects.	PAX7 FOXA2	4.11e-04	13	81	2	23283079
Pubmed	Perivascular cells expressing annexin A5 define a novel mesenchymal stem cell-like population with the capacity to differentiate into multiple mesenchymal lineages.	PTPRC PAX7	4.11e-04	13	81	2	15857912
Pubmed	Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.	PAX7 FOXA2	4.79e-04	14	81	2	20463034
Pubmed	A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling.	PAX7 FOXA2	4.79e-04	14	81	2	19776033
Pubmed	Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse.	PAX7 FOXA2	4.79e-04	14	81	2	19877275
Pubmed	GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons.	PAX7 FOXA2	4.79e-04	14	81	2	21246650
Pubmed	Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.	PAX7 FOXA2	4.79e-04	14	81	2	22549777
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	SRCAP CIC	4.79e-04	14	81	2	28263302
Pubmed	Targeted disruption of the homeobox gene Nkx2.9 reveals a role in development of the spinal accessory nerve.	PAX7 FOXA2	4.79e-04	14	81	2	12571110
Pubmed	Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice.	PAX7 FOXA2	4.79e-04	14	81	2	8756299
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	FLNA PTPRA DSP HERC1 DNAH5	4.83e-04	277	81	5	30745168
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	TGIF1 COL6A2 DSP KLHDC3 FAT3 REL SALL4 BCAR3 MDK ARHGAP45	5.17e-04	1215	81	10	15146197
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	UIMC1 ATP6V1A MAP7D1 KLHDC3 PTPN23 EGFL7 HERC1	5.27e-04	604	81	7	38803224
Pubmed	Mouse Shh is required for prechordal plate maintenance during brain and craniofacial morphogenesis.	PAX7 FOXA2	5.52e-04	15	81	2	19103193
Pubmed	Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice.	PAX7 FOXA2	5.52e-04	15	81	2	23071453
Pubmed	SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity.	PTPRC PAX7	5.52e-04	15	81	2	29882512
Pubmed	β1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs.	PAX7 FOXA2	5.52e-04	15	81	2	33051257
Pubmed	Mitochondrial Raf1 Regulates Glutamine Catabolism.	ATP6V1A PTPN13 MDK ARHGAP45 PPID	5.77e-04	288	81	5	38496616
Pubmed	The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.	FLNA PTPN13	6.29e-04	16	81	2	18824598
Pubmed	Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord.	PAX7 FOXA2	6.29e-04	16	81	2	24948600
Pubmed	Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons.	PAX7 FOXA2	6.29e-04	16	81	2	12787506
Pubmed	Boc is a receptor for sonic hedgehog in the guidance of commissural axons.	PAX7 FOXA2	6.29e-04	16	81	2	17086203
Pubmed	Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner.	PAX7 FOXA2	6.29e-04	16	81	2	34346313
Pubmed	The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.	PAX7 FOXA2	6.29e-04	16	81	2	17504941
Pubmed	Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.	PAX7 FOXA2	6.29e-04	16	81	2	28800946
Pubmed	Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system.	PAX7 FOXA2	6.29e-04	16	81	2	9655799
Pubmed	The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling.	PAX7 FOXA2	6.29e-04	16	81	2	31964774
Pubmed	Hedgehog signalling in the mouse requires intraflagellar transport proteins.	PAX7 FOXA2	6.29e-04	16	81	2	14603322
Pubmed	TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration.	PAX7 FOXA2	7.12e-04	17	81	2	35950911
Pubmed	Protein tyrosine phosphatases expression during development of mouse superior colliculus.	PTPN2 PTPRA	7.12e-04	17	81	2	19727691
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN2 PTPN13 PTPN23	2.22e-05	18	56	3	812
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRA PTPRC PTPRH	3.60e-05	21	56	3	813
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP40 SRGAP2 ARHGAP45	4.98e-04	50	56	3	721
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	SRGAP2 ARHGAP45	2.29e-03	23	56	2	1288
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE28 MTMR4	4.14e-03	31	56	2	81
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3	PTPN13 SCUBE2 RSL1D1 TRIM8 SALL4 MTCL1 PAX7 PPID	9.93e-06	285	78	8	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#5	SCUBE2 RSL1D1 SALL4 MTCL1	7.50e-05	61	78	4	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500	PROM1 PTPN13 SCUBE2 USP51 RSL1D1 SALL4 MTCL1 PAX7 NKRF	8.41e-05	496	78	9	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	PROM1 SCUBE2 USP51 RSL1D1 FAT3 ADGRB3 SALL4 NCKAP5 MTCL1	8.67e-05	498	78	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|metastatic_Brain / Location, Cell class and cell subclass	PTPRC GZMK KIF19 ADGRB3 PCSK7 ARHGAP45 FCRL6	2.78e-08	171	81	7	d3e1cc1b70256c4d01488d6b6130bbcae99bdeec
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	PROM1 SCUBE2 ARHGAP40 TBC1D30 SALL4 DNAH5	8.65e-07	177	81	6	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	FLNA COL6A2 PTPRA PTPRC KIF19 FCRL6	1.12e-06	185	81	6	097d628f92e13250c15b550f2fd1f4225fc07558
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PROM1 ATP6V1A SCUBE2 FAT3 DNAH5 SLC2A12	1.27e-06	189	81	6	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PROM1 COL6A2 SCUBE2 FAT3 CAMK1G MDK	1.35e-06	191	81	6	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PROM1 COL6A2 SCUBE2 FAT3 CAMK1G MDK	1.39e-06	192	81	6	0afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FLNA COL6A2 PTPRC KIF19 PCSK7 FCRL6	1.43e-06	193	81	6	d66cbb8c71bdc57faecb74a16fe3f34cb0b33228
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FLNA COL6A2 PTPRC KIF19 PCSK7 FCRL6	1.43e-06	193	81	6	c1d9c2436503791350086a503d6b98c5c69f44ae
ToppCell	lymphoid-NK_cell-NK_cell\|World / Lineage, cell class and subclass	FLNA COL6A2 GZMK KIF19 REL FCRL6	1.48e-06	194	81	6	7f5adc18e632109694446b8eb1543cbae62dccbe
ToppCell	IIF-Lymphocyte-T_NK-CD8_TEM\|IIF / Disease, Lineage and Cell Type	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.48e-06	194	81	6	f4f7c85963ba52ee7ca2ef5657e60680fe6332fe
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD8_TEM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.48e-06	194	81	6	fa53f1aab2f5923e90f090e10e3560b583441dc4
ToppCell	lymphoid-NK_cell\|World / Lineage, cell class and subclass	FLNA COL6A2 GZMK KIF19 REL FCRL6	1.48e-06	194	81	6	4bf5a140be8691e4ec99d7ee15588fd48acd6fb5
ToppCell	COVID-19_Severe-CD8+_Tem\|COVID-19_Severe / Disease condition and Cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.52e-06	195	81	6	ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PTPN13 SCUBE2 ARHGAP40 DSP NCKAP5 DNAH5	1.66e-06	198	81	6	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PTPN13 SCUBE2 ARHGAP40 DSP NCKAP5 DNAH5	1.66e-06	198	81	6	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	COVID-19_Moderate-CD8+_Tem\|COVID-19_Moderate / disease group, cell group and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.71e-06	199	81	6	adcaf9bd73933259dcf7983ca369a98e2f312d0b
ToppCell	COVID-19_Mild-CD8+_Tem\|COVID-19_Mild / Disease condition and Cell class	FLNA COL6A2 GZMK KIF19 REL FCRL6	1.71e-06	199	81	6	9016fbe5fe55e1ffa279ee8e8db3c93b5cf914d5
ToppCell	remission-CD8+_Tem\|World / disease stage, cell group and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	0ebf0dda91fc7adb9ea69734ad9dcc65d0082c6d
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD8+_Tem\|COVID-19_Convalescent / Disease, condition lineage and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	7c8a5465b478f430495942151c36020023d9bac9
ToppCell	severe-CD8+_Tem\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCell	remission-CD8+_Tem\|remission / disease stage, cell group and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	f1e4b8fcb422727f665f22b48f34bee23f0fad52
ToppCell	MS-IIF-Lymphocyte-T/NK-CD8+_Tem\|IIF / Disease, condition lineage and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	d75582d50f178ec67490fc298d42b10e18640c5a
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	94d4f690bf5b87866c0840715396d360b1737d11
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-CD8+_Tem\|Multiple_Sclerosis / Disease, condition lineage and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	cba63f8f2e7530e5539f7f5d93b3bcf5d693f6b9
ToppCell	severe-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FLNA COL6A2 PTPRC GZMK KIF19 FCRL6	1.76e-06	200	81	6	6aa77955017d073a96324e4db6b9950a2ec46cf8
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	ATG16L1 MAB21L4 ZNF805 ZNF625 NKRF	1.07e-05	159	81	5	2fb1d2ff52920aeb48d048cf29f0cd45f944a73d
ToppCell	tumor_Lung-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	FLNA GZMK KIF19 DNAH5 FCRL6	1.24e-05	164	81	5	60fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	PROM1 FAT3 ADGRB3 EGFL7 FOXA2	1.28e-05	165	81	5	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP MAB21L4 MTCL1 FOXA2 SLC2A12	1.31e-05	166	81	5	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP MAB21L4 MTCL1 FOXA2 SLC2A12	1.31e-05	166	81	5	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPN2 MTMR4 TBC1D30 OSMR ARHGAP45	1.47e-05	170	81	5	0f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 PTPRC GZMK CAMK1G WDR47	1.56e-05	172	81	5	2b0333c21b7472194a7b9feb3de121da3340fc5b
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PROM1 DSP CLEC14A SRGAP2 PRC1	1.65e-05	174	81	5	9d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PROM1 DSP CLEC14A SRGAP2 PRC1	1.65e-05	174	81	5	53cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors\|lymph-node_spleen / Manually curated celltypes from each tissue	PROM1 EGFL7 PRC1 MDK FOXA2	1.65e-05	174	81	5	029394e107bf7ad58056d2216070aa2e964fff12
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PROM1 ARHGAP40 SALL4 MDK DNAH5	1.70e-05	175	81	5	af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|356C / Donor, Lineage, Cell class and subclass (all cells)	PROM1 ARHGAP40 SALL4 MDK DNAH5	1.70e-05	175	81	5	4bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCell	10x3'2.3-week_12-13-Lymphocytic_T-T_NK-NK_T_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PTPRC GZMK PCSK7 ARHGAP45 FCRL6	1.79e-05	177	81	5	e1ba7e17af2c54d3c78cdf85882168c5b896e453
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN13 SCUBE2 ARHGAP40 NCKAP5 DNAH5	1.94e-05	180	81	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	COVID-19-Epithelial-Ionocytes\|Epithelial / Condition, Lineage and Cell class	ATP6V1A COL6A2 SCUBE2 ADGRB3 SLC2A12	1.99e-05	181	81	5	4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMK+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	COL6A2 PTPRC GZMK PCSK7 FCRL6	2.10e-05	183	81	5	79defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLEC14A ADGRB3 SHE GRIN2B EGFL7	2.10e-05	183	81	5	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN13 ARHGAP40 OSMR DNAH5 DNMT3L	2.16e-05	184	81	5	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-B_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 PTPRC REL BCAR3 ARHGAP45	2.27e-05	186	81	5	d5d990d8b6ccd8ca8fe7d0d7dedbe2359ae7b582
ToppCell	Control-Lymphocyte-T_NK-CD8_TEM\|Control / Disease, Lineage and Cell Type	COL6A2 PTPRC GZMK PCSK7 FCRL6	2.33e-05	187	81	5	7fdff970a9397305d0b8194c00a043cc69dcca12
ToppCell	facs-MAT-Fat-3m-Lymphocytic-B_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 PTPRC REL BCAR3 ARHGAP45	2.39e-05	188	81	5	a7158b5c94e6b356877f016e52f2c24a3f5d24d2
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A2 PTPN13 SCUBE2 SALL4 DNAH5	2.39e-05	188	81	5	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA COL6A2 FAT3 MTCL1 OSMR	2.45e-05	189	81	5	63449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 PTPN13 SCUBE2 FAT3 ADGRB3	2.45e-05	189	81	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	control-CD8+_Tem\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL6A2 PTPRC GZMK KIF19 FCRL6	2.52e-05	190	81	5	1200074e358f164d36bf22800a17ce0fca319560
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	PROM1 SCUBE2 ARHGAP40 DSP DNAH5	2.52e-05	190	81	5	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	COL6A2 SCUBE2 FAT3 CAMK1G MDK	2.52e-05	190	81	5	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	PTPRC GZMK PCSK7 ARHGAP45 FCRL6	2.52e-05	190	81	5	4240d52a465bc3f8016834b22a35c44ba2b0a9f4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 SCUBE2 FAT3 ADGRB3 OSMR	2.58e-05	191	81	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	hematopoetic_progenitors-CD34+_CLP\|World / Lineage and Cell class	PROM1 CLEC14A FAT3 EGFL7 MDK	2.58e-05	191	81	5	32f2537c97c9984629d61c6f34a337f555146ad4
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN13 SCUBE2 ARHGAP40 NCKAP5 DNAH5	2.58e-05	191	81	5	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL6A2 FAT3 PAX7 OSMR MDK	2.58e-05	191	81	5	cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL6A2 FAT3 PAX7 OSMR MDK	2.58e-05	191	81	5	c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCell	Leuk-UTI-Lymphocyte-T_NK-CD8_TEM\|Leuk-UTI / Disease, Lineage and Cell Type	COL6A2 GZMK KIF19 PCSK7 FCRL6	2.65e-05	192	81	5	2787b52546eedada4aa413025b86841c351273f4
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FLNA COL6A2 PTPRC KIF19 FCRL6	2.65e-05	192	81	5	01d01c9293f2439dc4c34c648273319c9beee5c7
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FLNA COL6A2 PTPRC KIF19 FCRL6	2.65e-05	192	81	5	0f8c63de26128694f4522f9f6d029e4628c890bc
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	PTPN13 SCUBE2 ARHGAP40 NCKAP5 DNAH5	2.71e-05	193	81	5	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 SCUBE2 FAT3 CAMK1G MDK	2.71e-05	193	81	5	8d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PROM1 COL6A2 SCUBE2 FAT3 MDK	2.71e-05	193	81	5	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	FLNA COL6A2 PTPRC KIF19 FCRL6	2.71e-05	193	81	5	3184a5f454e3ac5a81f6bacf9bd8f07d9d448fba
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+\|normal / PBMC cell types (v2) per disease, treatment status, and sex	FLNA COL6A2 PTPRC KIF19 FCRL6	2.71e-05	193	81	5	123d4d13c8944c32bf4a5d7fdc65e3b65aa568ef
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN13 SCUBE2 ARHGAP40 NCKAP5 FOXA2	2.78e-05	194	81	5	5b29c843186c2394f5bec3b1d5ae284a0d931d85
ToppCell	metastatic_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T\|metastatic_Lymph_Node / Location, Cell class and cell subclass	FLNA PTPRC GZMK KIF19 FCRL6	2.78e-05	194	81	5	73c057b623829de793616d9d373a0018071d51d8
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.78e-05	194	81	5	e72be6dc2711c1d4f16943c8615cf9dc2e961ff3
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN13 SCUBE2 ARHGAP40 NCKAP5 FOXA2	2.78e-05	194	81	5	ebcf6c6d0eb20a5d422becf5a730089230c8ba9a
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.78e-05	194	81	5	ac03be73fdc32dacd4a450c0fb28617e043b8444
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN13 SCUBE2 ARHGAP40 NCKAP5 FOXA2	2.78e-05	194	81	5	8c6e5ba27a988e0cd6b8c25cb9a30a0da2b1f7f9
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.78e-05	194	81	5	7ab4418a8a12c488d74af3676bdac672628da80c
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP31 CLEC14A SHE EGFL7 BCAR3	2.78e-05	194	81	5	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN13 SCUBE2 ARHGAP40 NCKAP5 FOXA2	2.78e-05	194	81	5	6e78e3046c5b172af92a84e25f982377a0aaac58
ToppCell	T/NK_cells-NKT_cell\|World / Lineage and Cell class	FLNA COL6A2 PTPRC KIF19 FCRL6	2.78e-05	194	81	5	8e09989ec2d1bbfe70cb18321c2ae94e0d0d9f18
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.78e-05	194	81	5	760761ce7d22edf9a8cec71e8ab0caa273fce3f7
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP31 CLEC14A SHE EGFL7 BCAR3	2.78e-05	194	81	5	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FLNA PTPRC KIF19 PCSK7 FCRL6	2.78e-05	194	81	5	95ab357d5f7bf91ba287417928c8575e655814fc
ToppCell	MS-CD8-CD8_1\|MS / Condition, Cell_class and T cell subcluster	FLNA PTPRC GZMK PCSK7 FCRL6	2.78e-05	194	81	5	9c05eb30c4b5c6fc410b83cb8aa8138bd46527c9
ToppCell	(1)_T_CD8_CTL\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	FLNA COL6A2 PTPRC GZMK FCRL6	2.85e-05	195	81	5	f582b854e5a4c52764aad5abe4e28ea77a7445f7
ToppCell	Control-CD8+_Tem\|Control / Disease condition and Cell class	FLNA PTPRC GZMK KIF19 FCRL6	2.85e-05	195	81	5	7503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCell	normal_Lung-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	FLNA PTPRC GZMK KIF19 FCRL6	2.85e-05	195	81	5	3af8ea15e2ac8efdeb4d4f69357b83b8dbcfab8d
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP7D1 CLEC14A SHE NCKAP5 EGFL7	2.85e-05	195	81	5	52b2bbf12e5f86c493f6634697aeb23a68cc916d
ToppCell	metastatic_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	FLNA COL6A2 PTPRC KIF19 FCRL6	2.85e-05	195	81	5	bff726515ea9ce82c223e6c805000afe2e9b7206
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FLNA PTPRC KIF19 PCSK7 FCRL6	2.85e-05	195	81	5	1a7c2c4cf30df435770794a989be438579bf98f2
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	FLNA COL6A2 PTPRC KIF19 FCRL6	2.92e-05	196	81	5	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZFYVE28 COL6A2 PTPRC GZMK FCRL6	2.92e-05	196	81	5	a2db88fad9bbc55685f8e681d120ef38715ca3c4
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.99e-05	197	81	5	2b3a56bb1d40bc1284a5931c4e7b373660de5402
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD8+_Tem\|COVID-19_Severe / Disease group, lineage and cell class	COL6A2 PTPRC GZMK KIF19 FCRL6	2.99e-05	197	81	5	f0bac4d5c3160933ac3786cec8dadffb35d711ea
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.99e-05	197	81	5	f73ece3aca28c0db5db0f12e026d42c6c36b9efb
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.99e-05	197	81	5	e70e7d97823a762def3970d94a0e897981a6c922
ToppCell	normal_Lung-T/NK_cells-Cytotoxic_CD8+_T\|normal_Lung / Location, Cell class and cell subclass	PTPRC GZMK PCSK7 ARHGAP45 FCRL6	2.99e-05	197	81	5	b4db3bfdfc09b5fb58d70d2d5e01c71231c64ae8
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	USP31 CLEC14A SHE NCKAP5 EGFL7	2.99e-05	197	81	5	b2b7f8dc8ca421441e4c99c4f5d18fbc1668d79f
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A2 PTPRC GZMK KIF19 FCRL6	2.99e-05	197	81	5	bce0135a96910d2bace62a3408a1a6fdac0cf0df
ToppCell	normal_Lung-T/NK_cells-CD8_low_T\|normal_Lung / Location, Cell class and cell subclass	PTPRC GZMK PCSK7 ARHGAP45 FCRL6	2.99e-05	197	81	5	559b22ff973a1551e614a972085343e7d8e8a668
ToppCell	Healthy-CD8+_Tem\|Healthy / disease group, cell group and cell class	COL6A2 PTPRC GZMK KIF19 FCRL6	2.99e-05	197	81	5	8d60fdd5ce80c3496637fd3257d25258df6d7f75
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	USP31 CLEC14A SHE NCKAP5 EGFL7	2.99e-05	197	81	5	6a3c647af41fea923311562575a0d656fbc13cbe
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNA COL6A2 PTPRC KIF19 FCRL6	3.07e-05	198	81	5	88bb764b21ca50e56f6c536a2d61d35afd8c3f36
ToppCell	COVID-19_Moderate-CD8+_Tem\|World / disease group, cell group and cell class	COL6A2 PTPRC GZMK KIF19 FCRL6	3.07e-05	198	81	5	1d12be256af028c88e31fb535068bae16b7bd48e
Disease	otitis media (implicated_via_orthology)	TGIF1 SALL4 DNAH5	2.35e-05	22	75	3	DOID:10754 (implicated_via_orthology)
Disease	cardiovascular disease biomarker measurement, ankle brachial index	FAT3 DNAH5	6.34e-05	5	75	2	EFO_0003912, EFO_0005278
Disease	hypersomnia	PTPRA NCKAP5	1.33e-04	7	75	2	EFO_0005246
Disease	gastric adenocarcinoma (is_marker_for)	PTPN13 PTPRA	2.31e-03	28	75	2	DOID:3717 (is_marker_for)
Disease	lifestyle measurement, depressive symptom measurement	USP31 PLPPR4 ADCY8	2.45e-03	105	75	3	EFO_0007006, EFO_0010724
Disease	muscular atrophy (biomarker_via_orthology)	TGIF1 MTMR4	2.48e-03	29	75	2	DOID:767 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QGPAGLTHKSACVGR	nan	131	A8MWP4
HSTCGTKVFPERSGS	ADCY8	101	P40145
GHSLSADGTLCVPKG	EGFL7	166	Q9UHF1
CVDSLVGPGTSGKVH	DNMT3L	121	Q9UJW3
SGTTGAPKCMVHSAG	AACS	291	Q86V21
GRGAKLPSCAQGSHT	BCAR3	441	O75815
HKDIGPCRAATITGT	ADGRB3	1201	O60242
SPSGSHVVSVDKGCK	ATG16L1	586	Q676U5
CGIAVIRTSGPASGH	GTPBP3	46	Q969Y2
AIVSGGHECGVATKP	GZMK	226	P49863
SDSGSCGHVPVSPKA	OSMR	866	Q99650
EALRGSGVTSSPHKC	MTCL1	1651	Q9Y4B5
TPIIVHCSSGVGRTG	PTPN23	1386	Q9H3S7
PAVIHCSAGIGRSGT	PTPN2	211	P17706
KGTAVETEGSGSRHP	SLC2A12	16	Q8TD20
GHCDRSTVPSGLVSS	PAX7	141	P23759
DGGPHKLSTGATNCL	ZFYVE28	546	Q9HCC9
ASSEGDAKCRGHIVP	MAB21L4	131	Q08AI8
VCHTGPGAEGHSRST	PTCRA	106	Q6ISU1
EGGCTEGTPAKDHRA	ARHGAP45	596	Q92619
TAAHRVVGPAASGCS	MAP10	141	Q9P2G4
TPSSKDCGVGFREGT	MDK	46	P21741
IGCHGSVEKSSSGRI	HERC1	3141	Q15751
PGTKLCHGDSELTSG	LINC00312	76	Q9Y6C7
KIVGNHSAPCGGTTS	FCRL6	246	Q6DN72
STCGPTKGHGRDVTA	FAM90A27P	191	A6NNH2
TGCTEGHTGTSAAAP	PCSK7	396	Q16549
EHCLRASPKTTLSGG	NSUN5P1	136	Q3KNT7
REGVKSPVCSSHSNG	MTMR4	956	Q9NYA4
PVKASGSSHCRAGQT	CAMK1G	456	Q96NX5
RLPHGTSTHGKDGCS	KIF19	981	Q2TAC6
TAGNSPHCRKPSGSG	DNAJB14	56	Q8TBM8
DASKCTVTVSIGGHG	FLNA	1641	P21333
CTGGIIHPTTGQKLS	DSP	2656	P15924
TDGHVTGSPCGGIKL	COL6A2	161	P12110
PGKLGECSGHTSLSF	FAT3	3826	Q8TDW7
SPGHKTSGSRCSVSA	MAP7D1	241	Q3KQU3
SGTVPGARDGHSACV	KLHDC3	121	Q9BQ90
TSVSPRVSLHCGKSG	SCUBE2	451	Q9NQ36
SPGSKDCHRENGGSS	SALL4	126	Q9UJQ4
SAGITGVSHCARPGE	C14orf178	56	Q8N769
LGPSGAGKTTCIHTL	DNAH5	2261	Q8TE73
SGPIITHCSAGIGRS	PTPN13	2401	Q12923
HPITVHCSAGAGRTG	PTPRA	726	P18433
GHTRCEKGADTAPGQ	nan	126	A6NNC1
SSASPCQEHKRGGLG	FOXA2	306	Q9Y261
KSHGSCAPPVSRAGG	PLD6	221	Q8N2A8
RTASGHEPGGSAVCA	PLEKHN1	211	Q494U1
TRDEHCGSGPEAGVK	NCKAP5	911	O14513
SSQCHTGSSPRGSGK	NKRF	421	O15226
LCTGEKGIGHTTGKP	PPID	51	Q08752
HATPTTRGCVSNTGG	PROM1	466	O43490
CSGKKTPRTGRHGAN	PRC1	531	O43663
GSSSVGHTAAVPRRC	SLC41A3	456	Q96GZ6
SEAFPTGHKGRGCSQ	SPATA31E1	946	Q6ZUB1
SCGTGGGTHRRSKKA	SRCAP	2371	Q6ZRS2
PGSSSCGAERLHTVG	CIC	331	Q96RK0
KDGRSCVTSGEGQPT	CLEC14A	281	Q86T13
GILGPTACTGESEKH	ZCCHC2	771	Q9C0B9
SRVSAGVGSPHCSGS	TGIF1	6	Q15583
AARLSCAVHTSPGGG	PLPPR4	26	Q7Z2D5
PSCVRVVGTTFHGTG	WDR47	786	O94967
GPTGCSHVESFKVGK	USP51	191	Q70EK9
RLHPAGSAGCSTGVE	ARHGAP40	11	Q5TG30
TPSSLAHSVGCGMRG	RBMXL3	166	Q8N7X1
SKSGSCSAIRIGHVG	RSL1D1	206	O76021
KVTARAGASCPSGGH	SRGAP2	811	O75044
GSSSRPSAGSHKQCG	TMEM131	1201	Q92545
TPCKNLRVGSHITGG	ATP6V1A	136	P38606
RTKSHPGCGDTVGLI	TBC1D30	741	Q9Y2I9
KCEGRSAGSIPGEHS	REL	26	Q04864
APGCKASGRGSRVTH	SNHG28	26	P0DPA3
VHKPGSTCDGSLKGR	UNQ6494/PRO21346	146	Q6UXR6
PHPGEKTCRGGSVES	ZNF843	166	Q8N446
PRVKSCGEVSVGHAS	ZNF625	31	Q96I27
RALKSCGPGGTAHVK	USP31	541	Q70CQ4
RGAAGDHGSCPTTTS	TOGARAM1	51	Q9Y4F4
TEEEPHRGATKSSGC	SHE	126	Q5VZ18
PCGVSSSGAEKRKHS	TRIM8	366	Q9BZR9
SGPIVVHCSAGVGRT	PTPRC	846	P08575
PIVHCSAGVGRTGTL	PTPRH	1016	Q9HD43
EHTQCGKPQESTGRG	UIMC1	226	Q96RL1
GHSGAVKCVAPLSSE	WDR81	1646	Q562E7
PKHDGLGTADSVCSR	ZNF805	156	Q5CZA5
SVSGGGPCTNRSHIK	GRIN2B	1166	Q13224