Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.31e-0728985GO:0001972
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.42e-0735985GO:0015020
GeneOntologyMolecularFunctionretinoid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.72e-0648985GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

4.13e-0649985GO:0019840
GeneOntologyMolecularFunctionmolecular function inhibitor activity

A2M SERPINE3 RASA1 UACA UGT1A10 UGT1A8 UGT1A7 UGT1A9 BIRC6 UGT1A1 A2ML1 PZP GPRC5B

6.89e-065969813GO:0140678
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A6 SLC12A5 SLC12A4

9.43e-069983GO:0015379
GeneOntologyMolecularFunctionenzyme inhibitor activity

A2M SERPINE3 UGT1A10 UGT1A8 UGT1A7 UGT1A9 BIRC6 UGT1A1 A2ML1 PZP GPRC5B

9.45e-064359811GO:0004857
GeneOntologyMolecularFunctionprotein kinase C binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 IRS1

1.81e-0566985GO:0005080
GeneOntologyMolecularFunctionprotein phosphorylated amino acid binding

RASA1 SCAF8 IRS1 SCAF4 HCK

2.25e-0569985GO:0045309
GeneOntologyMolecularFunctionammonium channel activity

SLC12A6 SLC12A5 SLC12A4

2.44e-0512983GO:0008519
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 CELSR3 OR51Q1 ACKR3 FZD10 C5AR1 OR2V2 GPRC5B

2.57e-058849815GO:0004930
GeneOntologyMolecularFunctionodorant binding

OR8U1 OR5G3 OR8U9 OR8U8 OR8B8 OR5AC2

3.84e-05127986GO:0005549
GeneOntologyMolecularFunctionsteroid binding

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 UGT1A1

4.97e-05133986GO:0005496
GeneOntologyMolecularFunctionolfactory receptor activity

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

5.10e-054319810GO:0004984
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GALNT18 ALG2 UGT1A1

8.17e-05211987GO:0016758
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GALNT18 UGT1A1

1.08e-04153986GO:0008194
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.84e-04107985GO:0033293
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC12A6 SLC12A5 SLC12A4

1.89e-0423983GO:0015377
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain phosphoserine binding

SCAF8 SCAF4

2.36e-045982GO:1990269
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC12A6 SLC12A5 SLC12A4

2.75e-0426983GO:0015296
GeneOntologyMolecularFunctionphosphoprotein binding

RASA1 SCAF8 IRS1 SCAF4 HCK

2.79e-04117985GO:0051219
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR8U1 HTR3A OR5G3 OR2J1 OR2J2 PLXND1 OR8U9 OR8U8 OR8B8 OR5AC2 CELSR3 OR51Q1 ACKR3 FZD10 C5AR1 OR2V2 GPRC5B

2.93e-0413539817GO:0004888
GeneOntologyMolecularFunctionfatty acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.69e-0469984GO:0005504
GeneOntologyMolecularFunctionC-X-C chemokine binding

A2M ACKR3

4.93e-047982GO:0019958
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GALNT18 ALG2 UGT1A1

5.46e-04288987GO:0016757
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain binding

SCAF8 SCAF4

1.27e-0311982GO:0099122
GeneOntologyMolecularFunctionphosphoserine residue binding

SCAF8 SCAF4

1.52e-0312982GO:0050815
GeneOntologyMolecularFunctionserine-type endopeptidase inhibitor activity

A2M SERPINE3 A2ML1 PZP

1.79e-03105984GO:0004867
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

A2M SERPINE3 BIRC6 A2ML1 PZP

1.94e-03180985GO:0004866
GeneOntologyMolecularFunctionphosphotyrosine residue binding

RASA1 IRS1 HCK

2.01e-0351983GO:0001784
GeneOntologyMolecularFunctionpeptidase inhibitor activity

A2M SERPINE3 BIRC6 A2ML1 PZP

2.30e-03187985GO:0030414
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A6 SLC12A5 SLC5A4 SLC12A4

2.81e-03119984GO:0015294
GeneOntologyMolecularFunctionendopeptidase regulator activity

A2M SERPINE3 BIRC6 A2ML1 PZP

3.13e-03201985GO:0061135
GeneOntologyMolecularFunctionprotein heterodimerization activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9 ALG2 UGT1A1 SEPHS1

3.47e-03398987GO:0046982
GeneOntologyMolecularFunctionprotein kinase binding

SLC12A6 CACNB3 RASA1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 IRS1 SLC12A5 SLC12A4 GPRC5B

3.66e-038739811GO:0019901
GeneOntologyMolecularFunctionenzyme regulator activity

A2M RANBP2 SERPINE3 RASA1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 IRS1 BIRC6 UGT1A1 A2ML1 PZP RASAL1 GPRC5B

3.76e-0314189815GO:0030234
GeneOntologyMolecularFunctionnuclear import signal receptor activity

TNPO1 TNPO2

4.28e-0320982GO:0061608
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC12A6 CACNB3 NDUFS7 HTR3A SLC12A5 SLC5A4 SLC12A4 UCP3 SCNN1B

5.34e-03664989GO:0008324
GeneOntologyBiologicalProcessflavone metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.24e-116975GO:0051552
GeneOntologyBiologicalProcesshormone metabolic process

TPO UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 FOXA1 UGT1A1 LHB DUOX1 DGAT2 SCNN1B PCSK4

8.80e-102869713GO:0042445
GeneOntologyBiologicalProcessestrogen catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.29e-095974GO:0006711
GeneOntologyBiologicalProcessflavonoid glucuronidation

UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.29e-095974GO:0052696
GeneOntologyBiologicalProcessflavonoid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.59e-0913975GO:0009812
GeneOntologyBiologicalProcessphenylpropanoid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.84e-096974GO:0046271
GeneOntologyBiologicalProcesscoumarin catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.84e-096974GO:0046226
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.97e-0821975GO:0052695
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.44e-0810974GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.44e-0810974GO:0009804
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.26e-0726975GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.26e-0726975GO:0006063
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.21e-0712974GO:0052697
GeneOntologyBiologicalProcesspotassium ion homeostasis

SLC12A6 CYP11B2 SLC12A5 SLC12A4 SCNN1B

8.02e-0737975GO:0055075
GeneOntologyBiologicalProcesshormone catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.59e-0621974GO:0042447
GeneOntologyBiologicalProcessregulation of hormone levels

TPO UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 IRS1 FOXA1 UGT1A1 LHB DUOX1 DGAT2 SCNN1B PCSK4

3.75e-066849714GO:0010817
GeneOntologyBiologicalProcessestrogen metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

4.52e-0652975GO:0008210
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 SCNN1B C5AR1 OR2V2

9.86e-065479712GO:0007606
GeneOntologyBiologicalProcesssteroid metabolic process

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 BDH1 UGT1A1 LHB DGAT2 SCNN1B

1.11e-053769710GO:0008202
GeneOntologyBiologicalProcesssecondary metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 N6AMT1

1.59e-0567975GO:0019748
GeneOntologyBiologicalProcesssteroid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.91e-0534974GO:0006706
GeneOntologyBiologicalProcessnegative regulation of termination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

2.19e-052972GO:2000805
GeneOntologyBiologicalProcessnegative regulation of termination of RNA polymerase II transcription

SCAF8 SCAF4

2.19e-052972GO:0120191
GeneOntologyBiologicalProcessammonium transmembrane transport

SLC12A6 SLC12A5 SLC12A4

2.79e-0513973GO:0072488
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

3.63e-054329710GO:0050911
GeneOntologyBiologicalProcessretinoic acid metabolic process

UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.69e-0540974GO:0042573
GeneOntologyBiologicalProcesssensory perception

CACNB3 OR8U1 MAP1A OR5G3 OR2J1 OR2J2 TULP2 OR8U9 OR8U8 OR8B8 SLC52A3 OR5AC2 OR51Q1 SCNN1B C5AR1 OR2V2

3.79e-0510729716GO:0007600
GeneOntologyBiologicalProcesscell volume homeostasis

SLC12A6 SLC12A5 SLC12A4 GPRC5B

4.49e-0542974GO:0006884
GeneOntologyBiologicalProcessketone metabolic process

UGT1A8 CYP11B2 UBR4 IRS1 UGT1A1 LHB DGAT2 SCNN1B

5.18e-05279978GO:0042180
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 N6AMT1

5.44e-05141976GO:0006805
GeneOntologyBiologicalProcessisoprenoid metabolic process

UGT1A8 UGT1A7 UGT1A9 ALG2 UGT1A1 DGAT2

6.12e-05144976GO:0006720
GeneOntologyBiologicalProcessretinoid metabolic process

UGT1A8 UGT1A7 UGT1A9 UGT1A1 DGAT2

6.30e-0589975GO:0001523
GeneOntologyBiologicalProcessnegative regulation of termination of DNA-templated transcription

SCAF8 SCAF4

6.55e-053972GO:0060567
GeneOntologyBiologicalProcesstermination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

6.55e-053972GO:0030846
GeneOntologyBiologicalProcessregulation of termination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

6.55e-053972GO:2000804
GeneOntologyBiologicalProcesssensory perception of smell

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

6.72e-054659710GO:0007608
GeneOntologyBiologicalProcesspigment metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

8.17e-0594975GO:0042440
GeneOntologyBiologicalProcessditerpenoid metabolic process

UGT1A8 UGT1A7 UGT1A9 UGT1A1 DGAT2

8.17e-0594975GO:0016101
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

CACNB3 OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

9.10e-055829711GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

9.52e-054859710GO:0050907
GeneOntologyBiologicalProcessammonium import across plasma membrane

SLC12A6 SLC12A4

1.31e-044972GO:0140157
GeneOntologyBiologicalProcessregulation of termination of RNA polymerase II transcription

SCAF8 SCAF4

1.31e-044972GO:1904594
GeneOntologyBiologicalProcessterpenoid metabolic process

UGT1A8 UGT1A7 UGT1A9 UGT1A1 DGAT2

1.38e-04105975GO:0006721
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

1.79e-045249710GO:0009593
GeneOntologyBiologicalProcesschloride ion homeostasis

SLC12A6 SLC12A5 SLC12A4

2.15e-0425973GO:0055064
GeneOntologyBiologicalProcessmonoatomic anion homeostasis

SLC12A6 SLC12A5 SLC12A4

3.03e-0428973GO:0055081
GeneOntologyBiologicalProcessregulation of termination of DNA-templated transcription

SCAF8 SCAF4

3.24e-046972GO:0031554
GeneOntologyBiologicalProcessdetection of stimulus

CACNB3 OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

5.78e-047229711GO:0051606
GeneOntologyBiologicalProcesshormone biosynthetic process

TPO CYP11B2 LHB DUOX1

6.36e-0483974GO:0042446
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 N6AMT1

6.36e-04222976GO:0071466
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 LHB OR5AC2 CELSR3 OR51Q1 ACKR3 FZD10 C5AR1 OR2V2 GPRC5B

7.61e-0413959716GO:0007186
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

RASA1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 SLC12A5 UGT1A1 N6AMT1 SCNN1B

8.22e-04525979GO:0009410
GeneOntologyBiologicalProcessC21-steroid hormone metabolic process

CYP11B2 LHB SCNN1B

1.24e-0345973GO:0008207
GeneOntologyBiologicalProcessgland development

UGT1A10 UGT1A8 UGT1A7 UGT1A9 IRS1 PLXND1 FOXA1 UGT1A1 NCOA1

1.26e-03558979GO:0048732
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.49e-0821975PF00201
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.49e-0821975PS00375
DomainUDP_glucos_trans

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.49e-0821975IPR002213
DomainKCL_cotranspt

SLC12A6 SLC12A5 SLC12A4

5.41e-074973IPR000076
DomainAA-permease/SLC12A_dom

SLC12A6 SLC12A5 SLC7A1 SLC12A4

4.65e-0622974IPR004841
DomainAA_permease

SLC12A6 SLC12A5 SLC7A1 SLC12A4

4.65e-0622974PF00324
DomainSLC12A_fam

SLC12A6 SLC12A5 SLC12A4

4.68e-067973IPR004842
DomainSLC12_C

SLC12A6 SLC12A5 SLC12A4

7.46e-068973IPR018491
DomainSLC12

SLC12A6 SLC12A5 SLC12A4

7.46e-068973PF03522
DomainA2M_N

A2M A2ML1 PZP

1.59e-0510973PF01835
DomainA2M_N

A2M A2ML1 PZP

1.59e-0510973IPR002890
DomainA-macroglobulin_rcpt-bd

A2M A2ML1 PZP

1.59e-0510973IPR009048
DomainALPHA_2_MACROGLOBULIN

A2M A2ML1 PZP

1.59e-0510973PS00477
DomainA2M

A2M A2ML1 PZP

1.59e-0510973PF00207
DomainA2M_N_2

A2M A2ML1 PZP

1.59e-0510973IPR011625
DomainA2M_comp

A2M A2ML1 PZP

1.59e-0510973IPR011626
DomainA2M_N_2

A2M A2ML1 PZP

1.59e-0510973PF07703
DomainA2M_recep

A2M A2ML1 PZP

1.59e-0510973PF07677
DomainA2M_comp

A2M A2ML1 PZP

1.59e-0510973PF07678
DomainMacroglobln_a2

A2M A2ML1 PZP

1.59e-0510973IPR001599
DomainKCC1

SLC12A6 SLC12A4

2.67e-052972IPR000622
DomainTerpenoid_cyclase/PrenylTrfase

A2M A2ML1 PZP

1.05e-0418973IPR008930
DomainOlfact_rcpt

OR8U1 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

2.06e-04393979IPR000725
DomainRNA_pol_II-bd

SCAF8 SCAF4

5.51e-047972IPR006903
DomainCTD_bind

SCAF8 SCAF4

5.51e-047972PF04818
DomainRPR

SCAF8 SCAF4

7.32e-048972SM00582
DomainThiol-ester_cl

A2M A2ML1

7.32e-048972PF10569
DomainCID

SCAF8 SCAF4

7.32e-048972PS51391
DomainMacrogloblnA2_thiol-ester-bond

A2M A2ML1

7.32e-048972IPR019565
DomainCID_dom

SCAF8 SCAF4

7.32e-048972IPR006569
DomainMacrogloblnA2_CS

A2M A2ML1

7.32e-048972IPR019742
DomainA2M_N_2

A2M A2ML1

7.32e-048972SM01359
Domain-

A2M A2ML1

7.32e-0489722.60.40.690
DomainA2M_recep

A2M A2ML1

7.32e-048972SM01361
DomainA2M

A2M A2ML1

7.32e-048972SM01360
Domain7tm_1

OR8U1 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 ACKR3 C5AR1 OR2V2

7.68e-046779711PF00001
DomainG_PROTEIN_RECEP_F1_1

OR8U1 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 ACKR3 C5AR1 OR2V2

8.46e-046859711PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8U1 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 ACKR3 C5AR1 OR2V2

9.08e-046919711PS50262
DomainGPCR_Rhodpsn

OR8U1 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 ACKR3 C5AR1 OR2V2

9.19e-046929711IPR000276
DomainHaem_peroxidase

TPO DUOX1

1.17e-0310972IPR010255
DomainAn_peroxidase

TPO DUOX1

1.17e-0310972PF03098
DomainPEROXIDASE_3

TPO DUOX1

1.17e-0310972PS50292
DomainHaem_peroxidase_animal

TPO DUOX1

1.17e-0310972IPR019791
Domain-

TPO DUOX1

1.17e-03109721.10.640.10
Domain-

A2M A2ML1

1.70e-03129721.50.10.20
DomainRasGAP

RASA1 RASAL1

2.33e-0314972SM00323
DomainIMPORTIN_B_NT

TNPO1 TNPO2

2.33e-0314972PS50166
DomainRasGAP_CS

RASA1 RASAL1

2.33e-0314972IPR023152
DomainGPCR_Rhodpsn_7TM

OR8U1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 ACKR3 C5AR1 OR2V2

2.51e-036709710IPR017452
DomainRasGAP

RASA1 RASAL1

2.68e-0315972PF00616
DomainRAS_GTPASE_ACTIV_1

RASA1 RASAL1

2.68e-0315972PS00509
DomainIBN_N

TNPO1 TNPO2

2.68e-0315972PF03810
DomainRAS_GTPASE_ACTIV_2

RASA1 RASAL1

2.68e-0315972PS50018
Domain-

RASA1 RASAL1

3.06e-03169721.10.506.10
DomainIBN_N

TNPO1 TNPO2

3.06e-0316972SM00913
DomainImportin-beta_N

TNPO1 TNPO2

3.45e-0317972IPR001494
DomainRasGAP_dom

RASA1 RASAL1

3.87e-0318972IPR001936
PathwayWP_ESTROGEN_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

8.54e-0822745MM15888
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.37e-0724745MM14599
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.70e-0725745M17787
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.70e-0725745MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.70e-0725745M605
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.10e-0726745M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.11e-0728745M19580
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 UGT1A1

4.03e-0755746M14933
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT1A10 UGT1A8 UGT1A9 UGT1A1

6.73e-0714744M39328
PathwayKEGG_RETINOL_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 DGAT2

1.00e-0664746M9488
PathwayREACTOME_PARACETAMOL_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.74e-0639745MM15695
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.25e-0641745M7399
PathwayREACTOME_ASPIRIN_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.61e-0645745MM15694
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A5 SLC12A4

4.79e-067743M27339
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A5 SLC12A4

4.79e-067743MM15081
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.76e-0651745M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.45e-0652745M14171
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 UGT1A1 N6AMT1 NCOA1

1.87e-05219748MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 UGT1A1 N6AMT1 NCOA1

1.93e-05220748M10320
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 N6AMT1

2.02e-05107746MM14595
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 N6AMT1

2.25e-05109746M18788
PathwayWP_IRINOTECAN_PATHWAY

UGT1A10 UGT1A9 UGT1A1

2.95e-0512743M39611
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.23e-0570745M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.70e-0572745M9257
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 OR2V2

6.10e-054177410M4072
PathwayREACTOME_ASPIRIN_ADME

UGT1A8 UGT1A7 UGT1A9 UGT1A1

8.10e-0544744M45014
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873

UGT1A7 UGT1A9 UGT1A1 NCOA1

8.86e-0545744M39615
PathwayWP_2Q37_COPY_NUMBER_VARIATION_SYNDROME

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 ACKR3

1.11e-04145746M45512
PathwayWP_METAPATHWAY_BIOTRANSFORMATION

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 UGT1A1

1.49e-04153746MM15844
PathwayREACTOME_DRUG_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.66e-04109745M45012
PathwayREACTOME_DRUG_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.99e-04119745MM15692
PathwayREACTOME_MINERALOCORTICOID_BIOSYNTHESIS

CYP11B2 LHB

4.02e-046742M27075
PathwayREACTOME_SENSORY_PERCEPTION

OR8U1 OR5G3 OR2J1 OR2J2 OR8U9 OR8U8 OR8B8 OR5AC2 OR51Q1 SCNN1B OR2V2

4.53e-046367411M41834
PathwayREACTOME_PARACETAMOL_ADME

UGT1A10 UGT1A9 UGT1A1

4.60e-0429743M45015
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

UGT1A9 UGT1A1 NCOA1

5.62e-0431743M39476
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

UGT1A9 UGT1A1 NCOA1

6.17e-0432743M39567
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RASGAP

RASA1 RASAL1

7.46e-048742M47935
PathwayREACTOME_THYROXINE_BIOSYNTHESIS

TPO DUOX1

9.56e-049742MM14833
PathwayREACTOME_THYROXINE_BIOSYNTHESIS

TPO DUOX1

1.19e-0310742M27120
PathwayREACTOME_MINERALOCORTICOID_BIOSYNTHESIS

CYP11B2 LHB

1.73e-0312742MM14749
Pubmed

Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.59e-13698520297805
Pubmed

Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.35e-1279858467709
Pubmed

Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.35e-1279858464825
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

8.91e-12898517179145
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

8.91e-12898520610558
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

8.91e-12898518052087
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.00e-11998522511988
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.99e-111098523642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.99e-111098511465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.99e-111098523371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.99e-111098522558097
Pubmed

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28.

UGT1A10 UGT1A7 UGT1A9 UGT1A1

5.93e-11498417558305
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.25e-101298520308471
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.25e-101298519419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.25e-101298511434514
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.03e-101398522085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.03e-101398525246029
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.14e-101498521646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.14e-101498510836148
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.14e-101498514672974
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.14e-10149859295054
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.83e-101698519414484
Pubmed

Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.85e-10698432527940
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.65e-101798520639394
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.33e-091898520056724
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.81e-091998523281178
Pubmed

Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.06e-09798427514509
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.53e-092498524625756
Pubmed

Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.

UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.93e-081198418695635
Pubmed

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

UGT1A7 UGT1A9 UGT1A1

2.17e-08398319364970
Pubmed

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

UGT1A10 UGT1A8 UGT1A9

2.17e-08398329519853
Pubmed

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

UGT1A7 UGT1A9 UGT1A1

2.17e-08398316636344
Pubmed

Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.

UGT1A8 UGT1A9 UGT1A1

2.17e-08398326247833
Pubmed

Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations.

UGT1A7 UGT1A9 UGT1A1

2.17e-08398324453052
Pubmed

Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin.

A2M A2ML1 PZP

2.17e-08398312183561
Pubmed

[Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G].

UGT1A7 UGT1A9 UGT1A1

2.17e-08398323789755
Pubmed

Alpha-2 macroglobulin controls trophoblast positioning in mouse implantation sites.

A2M A2ML1 PZP

2.17e-08398314580373
Pubmed

Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer.

UGT1A7 UGT1A9 UGT1A1

2.17e-08398317406868
Pubmed

Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.

UGT1A8 UGT1A7 UGT1A1

2.17e-08398319996319
Pubmed

alpha2-macroglobulin- and murinoglobulin-1- deficient mice. A mouse model for acute pancreatitis.

A2M A2ML1 PZP

2.17e-08398310487856
Pubmed

Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.

UGT1A10 UGT1A8 UGT1A9

2.17e-08398312847094
Pubmed

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.

A2M A2ML1 PZP

8.66e-08498327031383
Pubmed

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy.

UGT1A7 UGT1A9 UGT1A1

8.66e-08498320628391
Pubmed

Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1.

UGT1A10 UGT1A9 UGT1A1

8.66e-0849832108603
Pubmed

Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.

SLC12A6 SLC12A5 SLC12A4

8.66e-08498312637262
Pubmed

Discovery and refinement of loci associated with lipid levels.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 IRS1 UGT1A1 DGAT2 A2ML1

1.58e-0721198824097068
Pubmed

Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers.

UGT1A7 UGT1A9 UGT1A1

2.16e-07598318597651
Pubmed

Distribution of mRNA coding for alpha-2-macroglobulin, the murinoglobulins, the alpha-2-macroglobulin receptor and the alpha-2-macroglobulin receptor associated protein during mouse embryogenesis and in adult tissues.

A2M A2ML1 PZP

2.16e-0759837514554
Pubmed

Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.

UGT1A8 UGT1A7 UGT1A9

2.16e-07598320565459
Pubmed

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

UGT1A10 UGT1A8 UGT1A9

2.16e-07598315057901
Pubmed

Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.

UGT1A7 UGT1A9 UGT1A1

4.31e-07698319204906
Pubmed

Human metabolic individuality in biomedical and pharmaceutical research.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.97e-075798521886157
Pubmed

Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism.

UGT1A8 UGT1A9 UGT1A1

1.20e-06898312695355
Pubmed

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

SLC12A6 SLC12A5 SLC12A4

1.20e-06898311395011
Pubmed

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

SLC12A6 SLC12A5 SLC12A4

1.20e-06898324393035
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A6 SLC12A5 SLC12A4

1.20e-06898321613606
Pubmed

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.

UGT1A8 UGT1A7 UGT1A1

1.20e-06898315319294
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.25e-066698519898482
Pubmed

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

A2M A2ML1 PZP

1.80e-0699837544347
Pubmed

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.

UGT1A10 UGT1A8 UGT1A9

1.80e-06998320732626
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A8 UGT1A9 UGT1A1

1.80e-0699831339448
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A6 SLC12A5 SLC12A4

1.80e-06998319323993
Pubmed

Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics.

UGT1A7 UGT1A9 UGT1A1

4.69e-061298319349540
Pubmed

Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import.

TNPO1 RANBP2

7.86e-06298232161167
Pubmed

Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes.

UGT1A9 UGT1A1

7.86e-06298215864130
Pubmed

Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes.

UGT1A7 UGT1A1

7.86e-06298215929176
Pubmed

Interethnic Variations of UGT1A1 and UGT1A7 Polymorphisms in the Jordanian Population.

UGT1A7 UGT1A1

7.86e-06298231132973
Pubmed

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

SLC12A6 SLC12A4

7.86e-06298234031912
Pubmed

Gilbert syndrome caused by a homozygous missense mutation (Tyr486Asp) of bilirubin UDP-glucuronosyltransferase gene.

UGT1A9 UGT1A1

7.86e-0629829627603
Pubmed

Coding defect and a TATA box mutation at the bilirubin UDP-glucuronosyltransferase gene cause Crigler-Najjar type I disease.

UGT1A9 UGT1A1

7.86e-0629829639672
Pubmed

Analysis of bilirubin uridine 5'-diphosphate (UDP)-glucuronosyltransferase gene mutations in seven patients with Crigler-Najjar syndrome type II.

UGT1A9 UGT1A1

7.86e-0629829621515
Pubmed

A phenylalanine codon deletion at the UGT1 gene complex locus of a Crigler-Najjar type I patient generates a pH-sensitive bilirubin UDP-glucuronosyltransferase.

UGT1A9 UGT1A1

7.86e-0629828226884
Pubmed

Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.

RHOXF2 RHOXF2B

7.86e-06298212087094
Pubmed

UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.

UGT1A9 UGT1A1

7.86e-06298218675828
Pubmed

Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk.

UGT1A7 UGT1A1

7.86e-06298218349289
Pubmed

Characterization of the uridine diphosphate-glucuronosyltransferase-catalyzing thyroid hormone glucuronidation in man.

UGT1A9 UGT1A1

7.86e-06298210946897
Pubmed

Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese.

UGT1A9 UGT1A1

7.86e-06298218981166
Pubmed

Identification of four genes coding for isoforms of murinoglobulin, the monomeric mouse alpha 2-macroglobulin: characterization of the exons coding for the bait region.

A2ML1 PZP

7.86e-0629827528167
Pubmed

Molecular characterization of the murinoglobulins.

A2ML1 PZP

7.86e-0629821840592
Pubmed

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

UGT1A10 UGT1A9

7.86e-06298225547628
Pubmed

Transportin-1 and Transportin-2: protein nuclear import and beyond.

TNPO1 TNPO2

7.86e-06298224780099
Pubmed

Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome.

UGT1A9 UGT1A1

7.86e-0629827715297
Pubmed

Genetic heterogeneity of Crigler-Najjar syndrome type I: a study of 14 cases.

UGT1A9 UGT1A1

7.86e-0629827989045
Pubmed

A mutation which disrupts the hydrophobic core of the signal peptide of bilirubin UDP-glucuronosyltransferase, an endoplasmic reticulum membrane protein, causes Crigler-Najjar type II.

UGT1A9 UGT1A1

7.86e-0629828706880
Pubmed

A genetic polymorphism in a functional domain of human pregnancy zone protein: the bait region. Genomic structure of the bait domains of human pregnancy zone protein and alpha 2 macroglobulin.

A2M PZP

7.86e-0629821692292
Pubmed

Identification of two single base substitutions in the UGT1 gene locus which abolish bilirubin uridine diphosphate glucuronosyltransferase activity in vitro.

UGT1A9 UGT1A1

7.86e-0629827906695
Pubmed

Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38.

UGT1A9 UGT1A1

7.86e-06298215286088
Pubmed

Influence of UDP-glucuronosyltransferase polymorphisms on mycophenolate mofetil-induced side effects in kidney transplant patients.

UGT1A8 UGT1A1

7.86e-06298218454993
Pubmed

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues.

UGT1A10 UGT1A8

7.86e-06298211901093
Pubmed

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.

UGT1A7 UGT1A9

7.86e-06298211677206
Pubmed

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.

SLC12A6 SLC12A4

7.86e-06298217510708
Pubmed

Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.

UGT1A10 UGT1A9

7.86e-06298222031623
Pubmed

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.

SCAF8 SCAF4

7.86e-06298231104839
Pubmed

Prolonged unconjugated hyperbilirubinemia associated with breast milk and mutations of the bilirubin uridine diphosphate- glucuronosyltransferase gene.

UGT1A9 UGT1A1

7.86e-06298211061796
Pubmed

Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line.

UGT1A9 UGT1A1

7.86e-06298218430559
Pubmed

Novel missense mutation of the UGT1A1 gene in Thai siblings with Gilbert's syndrome.

UGT1A9 UGT1A1

7.86e-06298212139570
Pubmed

Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.

UGT1A10 UGT1A8

7.86e-06298210497143
Pubmed

Murinoglobulin, a novel protease inhibitor from murine plasma. Isolation, characterization, and comparison with murine alpha-macroglobulin and human alpha-2-macroglobulin.

A2ML1 PZP

7.86e-0629822578455
Pubmed

Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.

UGT1A8 UGT1A9

7.86e-06298218568343
Pubmed

Rhox homeobox gene cluster: recent duplication of three family members.

RHOXF2 RHOXF2B

7.86e-06298216496311
Cytoband2q37

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.50e-09319852q37
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 ACKR3

9.61e-06226986chr2q37
GeneFamilyUDP glucuronosyltransferases

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.10e-0732825363
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2M A2ML1 PZP

7.41e-0698231234
GeneFamilyOlfactory receptors, family 8

OR8U1 OR8U9 OR8U8 OR8B8

7.13e-0549824155
GeneFamilySolute carriers

SLC12A6 SLC12A5 SLC5A4 SLC52A3 SLC7A1 SLC12A4 UCP3 SLC49A3

4.21e-04395828752
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA1 RASAL1

8.93e-0410822830
GeneFamilyArmadillo repeat containing|Importins

TNPO1 TNPO2

2.97e-0318822596
ToppCellBasal_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL16A1 UGT1A10 FERMT1 GALNT18 FZD10

3.00e-0516696523c04d1fba0c1733ccd0e4378fae2edde4fd0a7b
ToppCell10x5'-GI_small-bowel-Myeloid_Mac-Macrophage|GI_small-bowel / Manually curated celltypes from each tissue

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

3.18e-05168965d5b746d6083c2c8155a0ea345ea368bf6617d5ca
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MS4A15 BDH1 ALG2 LMLN TTC21B

3.36e-05170965d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCellT_cells-GZMK+_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

A2M HLA-DPB1 C5AR1 PZP HCK

4.30e-05179965798f208014f2229c597934775646ddbbacf94b69
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPB1 SLC12A5 IFI30 C5AR1 HCK

4.53e-0518196508bc6fe2a11d31a7e5e4a4552b04c0ebc2aefc59
ToppCellControl-Myeloid-Alveolar_macrophages|Control / group, cell type (main and fine annotations)

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

4.53e-051819658d2102c8c86c59a82610f26f90946b290552e666
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPB1 HORMAD1 IFI30 C5AR1 HCK

4.65e-05182965ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCell3'_v3-GI_small-bowel-Myeloid_Dendritic|GI_small-bowel / Manually curated celltypes from each tissue

HTR3A HLA-DPB1 DGAT2 IFI30 HCK

4.77e-051839656109199cf25b28831193a5ed7925b5bf38c6eb43
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TPO PLXND1 PZP GPRC5B

4.90e-05184965842473fa415575441b595073a994b6d621169776
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HTR3A HLA-DPB1 DGAT2 HCK RASAL1

4.90e-05184965315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Monocytes|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPB1 HORMAD1 IFI30 C5AR1 HCK

5.03e-05185965f8de11dd53b34d36368a2082f24ec1416cb7dbae
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M UACA PLXND1 SLC5A4 GPRC5B

5.03e-05185965602536a3308a848f106adcb0a83530997440c8f4
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Erythrophagocytic_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

A2M HLA-DPB1 SLC12A5 IFI30 HCK

5.16e-05186965a0cc925af97e47efd0c9bc17c37963e8ad4e5b35
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M SHOX PZP SENP7 RPL17

5.29e-05187965cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M UACA GALNT18 PZP GPRC5B

5.29e-05187965d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M SHOX PZP SENP7 RPL17

5.29e-05187965b426a67b5669019115b58295ce7d304beeb75825
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M UACA PLXND1 GALNT18 GPRC5B

5.56e-05189965db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

5.56e-05189965a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPB1 CELSR3 IFI30 C5AR1 RASAL1

5.56e-05189965b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TPO PLXND1 GALNT18 SLITRK2 CDH8

5.85e-051919651de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RANBP2 SLC52A3 SLC7A1 SCNN1B RASAL1

5.85e-0519196565083daf317f66556dc047eb19297dcbe9c70299
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M UACA PLXND1 GALNT18 GPRC5B

5.99e-051929655a0615fdc217554ccd611504b16e5d97628e207d
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M UACA PLXND1 GALNT18 ACKR3

5.99e-051929651f35efb0765e05f7f9c881849953bef3965be25a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M SHOX PZP SENP7 RPL17

5.99e-0519296597c312c82ec025c13052f8d424b11c0034c8ea54
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M UACA PLXND1 SLC5A4 GPRC5B

5.99e-0519296556b021c297a21dff357531f21e2464f85186106d
ToppCellMonocytes-C1QA+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

A2M HLA-DPB1 IFI30 C5AR1 HCK

6.30e-051949653e104e85574894c04791252d466d438fc809dde3
ToppCellCF-Myeloid-cDC|Myeloid / Disease state, Lineage and Cell class

A2M HLA-DPB1 ALG2 SLC7A1 RASAL1

6.30e-051949653feb8a0ba3368673c53e9cbd4980e73d18697718
ToppCell343B-Myeloid-Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

6.45e-0519596548ba2044d2459c8b0d17bc7deca8d0195ac6a00e
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TPO PLXND1 GALNT18 GPRC5B

6.61e-05196965c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCellMonocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

A2M HLA-DPB1 IFI30 C5AR1 HCK

6.61e-05196965ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TPO PLXND1 GALNT18 GPRC5B

6.61e-05196965a0ba408b802fa6d6e42e6d234b6879fdb1583f81
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

UGT1A10 UGT1A7 FERMT1 IRS1 HORMAD1

6.61e-051969653b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellMonocytes-IL1B+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

A2M HLA-DPB1 IFI30 C5AR1 HCK

6.61e-051969657bc0735d324ac5a1661434cda4116ddd58296730
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M UACA GALNT18 SLC52A3 SLC7A1

6.61e-05196965889c9fed857f64664ca1f47fcec9fecb15ed103c
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

A2M UACA PLXND1 GALNT18 GPRC5B

6.77e-05197965b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCellMacrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

IFI30 SLC49A3 C5AR1 SPOCD1 HCK

6.77e-05197965598fb7a9a8400af49d90807b3155d3cc1c34f505
ToppCell3'-Child09-12-SmallIntestine-Endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TPO PLXND1 GALNT18 GPRC5B

6.77e-0519796586a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M HLA-DPB1 IFI30 C5AR1 HCK

6.77e-05197965e698a0bbb20bd4868ff4348f2ac9f609942b55fa
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TPO PLXND1 GALNT18 GPRC5B

6.77e-05197965947042f888335c0829d4d5daeb623973eadb3348
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M PLXND1 GALNT18 SLC52A3 SLC7A1

6.93e-05198965218f33e068eb126458ec33176de3cfa6fc06ddf0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M PLXND1 GALNT18 SLC52A3 SLC7A1

6.93e-0519896572e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M PLXND1 GALNT18 SLC52A3 SLC7A1

6.93e-05198965e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

A2M UACA PLXND1 GALNT18 GPRC5B

6.93e-051989652630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

A2M UACA PLXND1 GALNT18 GPRC5B

6.93e-051989651e83bec16dcd60460422625f89952ff506d6be51
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FERMT1 GALNT18 DUOX1 SCNN1B C5AR1

6.93e-051989655374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_CCL|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DGAT2 IFI30 C5AR1 HCK RASAL1

7.10e-0519996552c06fcc112da21b1d914a896c04bde06fc756fe
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M PLXND1 GALNT18 SLC52A3 SLC7A1

7.10e-051999659c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.10e-051999658990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.10e-0519996596070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M PLXND1 GALNT18 SLC52A3 SLC7A1

7.10e-0519996572b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 PLXND1 SLC12A5 C5AR1 HCK

7.10e-0519996554167894a16e975d0541cbe3e515bcfa183044f6
ToppCellmetastatic_Brain-Myeloid_cells|metastatic_Brain / Location, Cell class and cell subclass

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.10e-05199965fdda25d26a5203bac00758ed6954638727ad194f
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.10e-0519996560e6312a149e23e4b486d92fb1f9625960b69c9d
ToppCellILEUM-inflamed-(7)_Endothelial_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

A2M UACA PLXND1 GALNT18 GPRC5B

7.10e-0519996597052c28e354833901f28d339b09f97f50a5b752
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_interstitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 SLC12A5 IFI30 C5AR1 HCK

7.10e-051999654b6d49b96bfcd6604b082bab620ae03276520885
ToppCellTransverse-Macrophage-Macrophage|Transverse / Region, Cell class and subclass

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.27e-0520096517548806ba38008050244151d1216c69ef8a8310
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

7.27e-05200965980cb0390586d8312890e8d0f3cf58e3309d16c5
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UACA ZC3H12B GALNT18 ZFPM2 SLC7A1

7.27e-05200965032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellTransverse-(6)_Macrophage|Transverse / shred on region, Cell_type, and subtype

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.27e-05200965b28350de555fa756d2631f004f71d5ac69b1affe
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 SLC12A5 IFI30 C5AR1 HCK

7.27e-052009651a080564de59abd59d3208a73441b6346e1c7cd8
ToppCellIIH-mono1-|IIH / Condition, Cell_class and T cell subcluster

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.27e-05200965555207143ecc89cdd55c30a513b31cf5dfd26dbc
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UACA ZC3H12B GALNT18 ZFPM2 SLC7A1

7.27e-0520096568fce28690246895fd33354b30960ebcc31aa4cc
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 SLC12A5 IFI30 C5AR1 HCK

7.27e-052009654b4df0fe47498310d94448b8a289e58e4f5b5aa8
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UACA ZC3H12B GALNT18 ZFPM2 SLC7A1

7.27e-05200965376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellTransverse-Macrophage|Transverse / Region, Cell class and subclass

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.27e-052009651920605e5811938814d02b971069a4506868db5f
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 SLC12A5 IFI30 C5AR1 HCK

7.27e-0520096577a68e8fd97a3f3467d25032067fd7ad52ab8522
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

7.27e-05200965d7d971586c01152b3d21956fd98280588cb8f08b
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UACA ZC3H12B GALNT18 ZFPM2 SLC7A1

7.27e-052009657fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M RANBP2 UCP3 IFI30 C5AR1

7.27e-05200965838f87cc55652512d240c5952ee4b3870fb2399f
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

7.27e-05200965efdbd1273b07d9fe957380e347b5b6b45db0a271
ToppCellIIH-mono1|IIH / Condition, Cell_class and T cell subcluster

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.27e-0520096585c090fa714a6a02703ed38d3d49788ec0119666
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DPB1 IFI30 C5AR1 SPOCD1 HCK

7.27e-052009659ca86928fceaa1fefd0f9ffcfa5cc0a210ee5792
ToppCellTransverse-(6)_Macrophage-(60)_Macrophage|Transverse / shred on region, Cell_type, and subtype

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.27e-052009652be675684a2958ea609939bb45248bede78a26bc
ToppCellmetastatic_Brain-Myeloid_cells-mo-Mac|metastatic_Brain / Location, Cell class and cell subclass

A2M HLA-DPB1 IFI30 C5AR1 HCK

7.27e-052009658f702d518f652782b0dd6ca3bdd965a79deb61f3
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UACA ZC3H12B GALNT18 ZFPM2 SLC7A1

7.27e-05200965878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UACA ZC3H12B GALNT18 ZFPM2 SLC7A1

7.27e-052009657136936d05ab344a560cf159684c881063b5430d
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

A2M SLC5A4 UGT1A1 PZP

1.37e-0412196419333a660800b583fa27b495c1f7828e6636a257
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Gpr139|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL16A1 ZFPM2 SLC12A4 RASAL1

2.02e-04134964917b8951dd4c870b6b92f2e73e02dac884330c30
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UGT1A9 UGT1A1 C5AR1 HCK

2.33e-0413996496e6fed23e7a69f678f85e8e2fe77a7491586b4b
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SERPINE3 MAP1A TULP2 SLC7A1

2.73e-04145964bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellChildren_(3_yrs)-Immune-mast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FERMT1 ZC3H12B PZP RASAL1

2.80e-04146964f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Cxcl14_(dSPN,_lateral_striatum)|Striatum / BrainAtlas - Mouse McCarroll V32

TPO VGLL2 MS4A15

2.95e-046096364d4de1de20d07c5f2e20b76854311a31718faa4
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Cxcl14_(dSPN,_lateral_striatum)-|Striatum / BrainAtlas - Mouse McCarroll V32

TPO VGLL2 MS4A15

2.95e-0460963b3941f8c3cf2365c5bf79961f62c9c0c7405a67b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DPB1 DGAT2 A2ML1 CDH8

2.95e-0414896412fa2c4922f03803006c606b1b16e79441e3bb13
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

A2M SLC7A1 SEPHS1 GPRC5B

3.03e-04149964a6c24d8f3b5f08587f0a12cd63d166b68ea000c7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNPO2 WBP2NL SLC7A1 A2ML1

3.03e-04149964c773c2b9685ec44a35246180a93456c8765353f5
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IFI30 SLC49A3 C5AR1 HCK

3.27e-04152964931c10245cde9b3290224cc1da46b2bf300b9ac2
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POLR1A IFI30 C5AR1 HCK

3.52e-0415596477ae0b8d30bc3db4a73fd5340f99691a73d2684f
ToppCellClub-club-7|World / Class top

MAP1A IRS1 TTC21B

3.57e-0464963df413c5328966480479c41826461c4d817fbe33d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 IRS1 PLXND1 ZFPM2

3.87e-04159964330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 IRS1 PLXND1 ZFPM2

3.87e-04159964cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX1 COL16A1 ZC3H12B FZD10

4.06e-041619649f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M UACA GALNT18 SLC5A4

4.26e-04163964977a970b1296234c22178420294cea73506ee02f
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SERPINE3 HTR3A PZP

4.27e-0468963ad6c363d7fb3c436e894db30a544748c5df75a45
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SERPINE3 HTR3A PZP

4.27e-046896382d928f5eefa065d26096a84b0d78f131dcc8c73
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SERPINE3 HTR3A PZP

4.27e-0468963d97199a8c6afa79bff1600f00c2dbf6286df24a2
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VGLL2 WBP2NL FOXA1

4.45e-04699634831573a45ace5f06cd409f0e75bce838ed65a88
ToppCellfacs-Heart-LV-24m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FERMT1 IFI30 C5AR1 HCK

4.46e-0416596441707e66542ea27133043740ef9e58ab89b06607
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

A2M UACA GALNT18 SLC5A4

4.46e-0416596484e553d699ac56df89a77248f7308b9133e1b683
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPB1 DUOX1 IFI30 HCK

4.56e-04166964da10d0be6b616199d49dd922591c2901f9681583
ComputationalNuclear pore complex.

TNPO1 RANBP2 TNPO2

6.92e-0517523MODULE_352
Drugnaringenin chalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.20e-125965ctd:C027329
Druganthrarobin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.20e-125965ctd:C032186
Drug1,2,5,8-tetrahydroxy anthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.17e-126965ctd:C543211
Drugalloin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.17e-126965ctd:C006457
Drug2',5'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.17e-126965ctd:C107497
Drug2-hydroxyestrone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 LHB

8.03e-1213966ctd:C024980
Drug2',4'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.50e-117965ctd:C059354
Drug1,4-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.65e-118965ctd:C034890
DrugAC1MRQNQ

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.49e-109965CID003522271
DrugDHPASiU

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.49e-109965CID000197602
Drug3-iodophenol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.49e-109965CID000012272
DrugAC1L4J7U

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.49e-109965CID000186631
DrugChebi:32663

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.49e-109965CID005460873
Drug2,6-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.97e-1010965ctd:C034889
Drug4-nitrophenyl)imidazole

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.43e-1011965CID000123155
DrugAC1O5XMV

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.43e-1011965CID006442661
DrugN-OH-DABZ

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.28e-1012965CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.28e-1012965CID000088735
Drug4-hydroxyestrone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.28e-1012965ctd:C026418
Drug2,4,6-TCB

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.28e-1012965CID000037247
Drugnonanoyl-N-methylglucamide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.28e-1012965CID000160090
Drug7,7,7-triphenylheptanoic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.28e-1012965CID000276709
Drugtritanol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.50e-0913965CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.50e-0913965CID003081279
Drugcotinine-N-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.50e-0913965CID000000411
Drugalizarin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.50e-0913965ctd:C010078
Drugpropranolol glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.33e-0914965CID000119515
DrugPCB-61

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.33e-0914965CID000036401
DrugPCB 156

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 UGT1A1

3.24e-0931966CID000038019
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.48e-0915965CID000040469
Drugafloqualone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.48e-0915965CID000002040
Drugnaphthyl sulphate

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.48e-0915965CID000114775
Drugcoumarin-3-carboxylic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.48e-0915965CID000010752
Drugbergamottin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.48e-0915965ctd:C068337
Drugsulforaphane nitrile

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.48e-0915965CID000543743
Drugquercetin-3,4'-diglucoside

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.05e-0916965CID005320835
Drug1'-hydroxyestragole

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.05e-0916965CID000040003
Drugbilirubin-phosphate

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.05e-0916965CID005497144
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.13e-0917965CID000003573
Drug6-hydroxychrysene

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.13e-0917965CID000037766
DrugSureCN12722713

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.84e-0918965CID005488034
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.84e-0918965CID000152226
DrugBr 2

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.84e-0918965CID003060900
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.84e-0918965CID000036614
DrugApApG

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.84e-0918965CID003081975
DrugC1 11-32

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.84e-0918965CID000443077
DrugC11131

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.84e-0918965CID000443076
Drug9-OH-risperidone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.33e-0819965CID000475100
Drug5alpha-spirostan-3beta-ol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.33e-0819965CID000091433
Drugalmokalant

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.33e-0819965CID003033962
Drugtectochrysin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.77e-0820965CID005281954
DrugAC1L1OBF

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.77e-0820965CID000032736
Drug4'-hydroxydiclofenac

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.77e-0820965CID000116545
Drugentacapone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.77e-0820965ctd:C071192
Drugtestosterone glucuronide

UGT1A10 UGT1A8 CYP11B2 UGT1A7 UGT1A9 UGT1A1

1.91e-0841966CID000108192
Drugglabridin

UGT1A10 UGT1A8 UGT1A9 UGT1A1

2.05e-088964ctd:C107601
Drugestriol-16-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.31e-0821965CID000122281
Drugdulcin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.31e-0821965CID000009013
DrugBenzamidoxime hydrochloride

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.31e-0821965CID000069186
Drugandrosterone glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 SLC12A4

2.58e-0843966CID000114833
Drugamonafide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.98e-0822965CID000050515
DrugN-methylpiperazine

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.98e-0822965CID000053167
Drugplumbagin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.98e-0822965ctd:C014758
Drugamidoxime

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.80e-0823965CID000465967
Drugestradiol-3-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.80e-0823965CID000066651
Drugphenanthridine

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.80e-0823965CID000009189
DrugAC1N8H7N

TNPO1 UGT1A10 TNPO2 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.93e-0878967CID004318740
DrugAS-3201

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

4.78e-0824965CID000153948
DrugEM-652

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 NCOA1

5.79e-0849966CID000155435
Drug5-MOP

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.96e-0825965CID000002355
DrugHymecromone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.96e-0825965ctd:D006923
DrugAzMC

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.96e-0825965CID000064986
DrugN-acetylbenzidine

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.96e-0825965CID000018787
Drug5,6-benzoquinoline

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.96e-0825965CID000006796
DrugN-phenylmaleimide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

5.96e-0825965CID000013662
Drugphenylbutazone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 C5AR1 RPL17

6.07e-0883967CID000004781
DrugGlucuronides

UGT1A10 UGT1A8 UGT1A9 UGT1A1

6.11e-0810964ctd:D020719
DrugThymol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

7.36e-0826965ctd:D013943
Drugbiochanin A

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 LHB NCOA1

8.42e-0887967ctd:C004541
Druglicochalcone A

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.00e-0827965ctd:C070840
Drugdiflunisal

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.00e-0827965CID000003059
DrugScopoletin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.00e-0827965ctd:D012603
DrugDiMeIQx

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.00e-0827965CID000104739
DrugEquol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 LHB

1.05e-0754966ctd:D060754
DrugCARMINE

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.09e-0728965CID000014749
Drugerucin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.09e-0728965CID000078160
DrugN-hydroxy-4-aminobiphenyl

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.09e-0728965CID000081261
DrugH-Ni

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.09e-0728965CID000445665
DrugAC1L1JAL

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.31e-0729965CID000004954
Drug7-hydroxycoumarin glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.31e-0729965CID000125641
Drug7-hydroxy-4-trifluoromethylcoumarin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.31e-0729965CID005375667
Drugtrans-3'-hydroxycotinine

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.31e-0729965CID000000414
Drugiberin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.31e-0729965CID000010455
Drug2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.31e-0729965ctd:C060533
Drugnorclozapine

HTR3A UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.46e-0757966CID000002820
Drugtolcapone

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.57e-0730965CID004659569
Drugparicalcitol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.57e-0730965CID005281104
DrugAC1L9E0Q

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.57e-0730965CID000443095
Drugdihydroartemisinin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.57e-0730965CID000107770
Drugmorin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 LHB

1.63e-0758966ctd:C008548
DiseaseX-11442 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.29e-119925EFO_0021236
DiseaseX-11441 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.29e-119925EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.29e-119925EFO_0004739
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.29e-119925EFO_0004570, GO_0009410
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.57e-1110925EFO_0802185
Diseasebilirubin measurement, response to tenofovir

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

6.57e-1110925EFO_0004570, EFO_0009279
DiseaseX-21796 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.20e-1011925EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.20e-1011925EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.20e-1011925EFO_0800972
Diseasealdosterone measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.20e-1011925EFO_0010219
Diseasebiliverdin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.05e-1012925EFO_0021033
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.41e-105924EFO_0801060
Disease5-hydroxyindole sulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.41e-105924EFO_0800085
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.41e-105924EFO_0801853
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.59e-0917925EFO_0004611, EFO_0007800
DiseaseX-21339 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.07e-097924EFO_0800808
DiseaseX-11793--oxidized bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0021260
DiseaseSuccinimide measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0022118
DiseaseX-11530 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0800696
DiseaseX-10458 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0800692
DiseaseX-24849 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0800909
Diseaseserum N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0600043
Diseaseplasma clozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0600038
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0802740
DiseaseX-16946 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.13e-098924EFO_0800766
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.10e-089924EFO_0801037
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.10e-089924EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.10e-089924EFO_0801036
DiseaseX-11880 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.10e-089924EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.10e-089924EFO_0020691
Diseaseindoleacetate measurement

UGT1A10 UGT1A8 UGT1A9 ACKR3

1.83e-0810924EFO_0021015
DiseaseX-21448 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.83e-0810924EFO_0800816
DiseaseX-23974 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.83e-0810924EFO_0800867
Diseasepregnenetriol sulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.87e-0811924EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.87e-0811924EFO_0600039
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A10 UGT1A8 UGT1A9

2.93e-083923EFO_0022216
Diseaseindole-3-carboxylate measurement

UGT1A10 UGT1A8 UGT1A9

2.93e-083923EFO_0800043
Diseasexanthurenate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

2.95e-0829925EFO_0010551
Diseaseresponse to dolutegravir

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

3.54e-0830925EFO_0600017
Diseasep-cresol glucuronide measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.30e-0812924EFO_0800079
Diseaseretinol dehydrogenase 16 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.19e-0813924EFO_0802007
Diseasepregnenetriol disulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.19e-0813924EFO_0800587
DiseaseX-21441 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.04e-0717924EFO_0800814
Diseaseangiopoietin-related protein 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.62e-0718924EFO_0801382
Diseasetissue factor measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.08e-0721924EFO_0010623
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A10 UGT1A8 UGT1A9

5.83e-076923EFO_0800566
Diseaseurate measurement, spine bone mineral density

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

1.06e-0658925EFO_0004531, EFO_0007701
Diseasegallstones

UGT1A10 UGT1A8 UGT1A7 RMI2 UGT1A9 UGT1A1

1.15e-06108926EFO_0004210
Diseaseneuroblastoma, cutaneous melanoma

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.71e-0628924EFO_0000389, EFO_0000621
Diseasetestosterone measurement

SOX1 POLR1A MAP1A UGT1A10 UGT1A8 CYP11B2 UGT1A7 RMI2 UGT1A9 BIRC6 ZFPM2 LHB TEX264 NCOA1 MINAR1 SPOCD1

1.91e-0612759216EFO_0004908
Diseasevitamin D deficiency

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.40e-0637924EFO_0003762
Diseasethyroxine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 SEPHS1

6.33e-0683925EFO_0005130
DiseaseX-24588 measurement

UGT1A10 UGT1A8 UGT1A9

8.20e-0613923EFO_0800898
Diseasecholelithiasis

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

8.43e-0688925EFO_0004799
Diseaseintellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)

TNPO1 TNPO2

9.62e-062922DOID:0081262 (implicated_via_orthology)
Diseasevitamin D measurement, COVID-19

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.68e-0549924EFO_0004631, MONDO_0100096
Diseasebilirubin measurement

TNPO1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 BIRC6 UGT1A1 DGAT2

7.38e-05442928EFO_0004570
Diseasehyperthyroidism (biomarker_via_orthology)

BDH1 UGT1A1 UCP3

9.08e-0528923DOID:7998 (biomarker_via_orthology)
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1

9.95e-05147925DOID:9352 (biomarker_via_orthology)
Diseasehormone measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.41e-0484924EFO_0004730
Diseasefree androgen index

UGT1A10 UGT1A8 UGT1A7 UGT1A9 ZFPM2 SEPHS1 MINAR1

1.73e-04374927EFO_0007005
Diseasedodecanedioate measurement

UGT1A10 UGT1A8

6.22e-0412922EFO_0021054
Diseaseserum metabolite measurement

TNPO1 HLA-DPB1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 UGT1A1 ACKR3 TXNDC16 SPOCD1

7.28e-049459210EFO_0005653
Diseasecongenital hypothyroidism (implicated_via_orthology)

TPO DUOX1

8.54e-0414922DOID:0050328 (implicated_via_orthology)
Diseasesyndrome (implicated_via_orthology)

SCAF8 SCAF4

1.42e-0318922DOID:225 (implicated_via_orthology)
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

RASA1 A2ML1

1.59e-0319922C3501846
DiseaseCostello syndrome (disorder)

RASA1 A2ML1

1.59e-0319922C0587248
DiseaseNoonan syndrome-like disorder with loose anagen hair

RASA1 A2ML1

1.59e-0319922C1843181
DiseaseCardio-facio-cutaneous syndrome

RASA1 A2ML1

1.59e-0319922C1275081
Diseaseintellectual disability (implicated_via_orthology)

UBR4 IRS1 TRAPPC9

1.68e-0375923DOID:1059 (implicated_via_orthology)
Diseasenon-high density lipoprotein cholesterol measurement

TNPO1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 SCAF4 UGT1A1 INTS10

1.75e-03713928EFO_0005689
Diseasemetabolite measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9 SLC12A5 UGT1A1 IFI30

1.86e-03560927EFO_0004725
Diseasehypothyroidism (biomarker_via_orthology)

MAP1A UCP3 NCOA1

2.03e-0380923DOID:1459 (biomarker_via_orthology)
DiseaseLEOPARD Syndrome

RASA1 A2ML1

2.13e-0322922C0175704
DiseaseNoonan Syndrome

RASA1 A2ML1

2.54e-0324922C0028326
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

IRS1 BIRC6 ZFPM2

2.66e-0388923EFO_0803332
DiseaseKidney Diseases

ACKR3 TTC21B RASAL1

2.66e-0388923C0022658

Protein segments in the cluster

PeptideGeneStartEntry
IVMEYLSFCPMQPAS

TTC21B

451

Q7Z4L5
LMSPYCGMHSPNIEV

BIRC6

3366

Q9NR09
TVQMMAYDKLVQCPP

CACNB3

316

P54284
MLGRMANPARSPYCI

BDH1

196

Q02338
SDCFGAMPMEQQYPP

COL16A1

1581

Q07092
LIPVADGMNEMYLRC

FERMT1

441

Q9BQL6
MPSGCGEQNMVLFAP

A2ML1

966

A8K2U0
LMVMDIVGFYLPPNS

HTR3A

256

P46098
VMLEMTPQQGDVYTC

HLA-DPB1

186

P04440
LPYQVTGIMMSFLEP

C5AR1

256

P21730
PKMCPQLQQYEMHGP

A2M

686

P01023
VLPSQCYQPLMELLM

RASAL1

261

O95294
CYQPLMELLMESVQG

RASAL1

266

O95294
ACMFSQEMYGPPALR

RANBP2

931

P49792
LLQMPYGCGEQNMVL

PZP

971

P20742
ICNPLLYMVTMSPQV

OR8B8

126

Q15620
ICPTPNNQFMMGGRY

RASA1

401

P20936
VLDLMCYMVLPIQDG

INTS10

516

Q9NVR2
STMVPPGVYMRNASC

DUOX1

331

Q9NRD9
ICNPLLYMVVMTPGI

OR8U8

126

P0C7N1
VMCMYLQPPSENSQD

OR2J1

256

Q9GZK6
TQCQKMDIPFLGEMP

NAXE

156

Q8NCW5
YEQMMLTGLGPACPT

MAP1A

1971

P78559
GYCPTMMRVLQAVLP

LHB

56

P01229
MYEMCLPEQEQRPPL

ZFPM2

741

Q8WW38
MDRPIAGYANLCPNM

LMLN

241

Q96KR4
QEDMPYIPLMEFSCS

PCNX4

891

Q63HM2
GPVLCGMSMDLPLYA

PCSK4

721

Q6UW60
LDSPEPMTVMVYNCA

PLXND1

836

Q9Y4D7
DGLIQMVVVMNFPYC

OR2V2

156

Q96R30
VIMANIYLLAPPVMN

OR51Q1

276

Q8NH59
IIANMSGCLPYMLPP

TPO

126

P07202
ICVGPENMQIMYPAI

MON2

1346

Q7Z3U7
VMCMYLQPPSENSPD

OR2J2

256

O76002
LPCTGDYMNMSPVGD

IRS1

726

P35568
ICNPLMYMVVMSPGI

OR8U9

126

P0C7N5
PACAYEPMDFVMALI

GPRC5B

191

Q9NZH0
VAICNPLLYPVMMSN

OR5AC2

126

Q9NZP5
AAAMNPCMSPMAYAP

FOXA1

131

P55317
PIEIPMCKDIGYNMT

FZD10

36

Q9ULW2
MPRPENCPEELYNIM

HCK

476

P08631
YAPGLSPDTIMECAM

IFI30

166

P13284
NVPIMYICHGMTPQN

GALNT18

491

Q6P9A2
TVMCPNMPNKSVLLY

ACKR3

31

P25106
TSMCQPPGIMQFEEP

MS4A15

31

Q8N5U1
MPLPERGMSYCPQAT

KLF17

91

Q5JT82
YNLGGPRMVCVMLPE

CYP11B2

81

P19099
MQNLGPLPNDVCLTM

HORMAD1

161

Q86X24
ITLPPCIYMAPMNQS

CDH8

21

P55286
LTYLNPMGLVTPNIM

CELSR3

2311

Q9NYQ7
KTPQMGTFMGVYLPC

SLC12A6

181

Q9UHW9
SINMIPPRGCAYIVM

SCAF4

536

O95104
INMIPPRGCAYVCMV

SCAF8

506

Q9UPN6
VEMSYPGEQMILACL

SCNN1B

236

P51168
MPVLREYLMSGGICP

DGAT2

201

Q96PD7
MSQQVCMQLVVGPYA

OR5G3

136

P0C626
QAPRMGTFMGVYLPC

SLC12A5

116

Q9H2X9
PQPCEMQRTYFPMNI

MINAR1

206

Q9UPX6
ICNPLLYMVVMTPGI

OR8U1

126

Q8NH10
VQMSSELCPYNPVME

SENP7

491

Q9BQF6
YVMVMGVVQACSPEP

RMI2

101

Q96E14
CPDMYINTNEIGIPM

POLR1A

446

O95602
YNMAMAVMSPCPLLQ

SLC52A3

376

Q9NQ40
LCYPQSPDMQPFIMG

NCOA1

346

Q15788
MPGGYALSQPVSCME

PPP1R32

371

Q7Z5V6
PVGQMCQNPIYMQKE

SLITRK2

691

Q9H156
PIVDDPYMMGRIACA

SEPHS1

91

P49903
VAPYVNMGALRMPFQ

SHOX

196

O15266
CTNYAYPTMVLELMP

SLC5A4

361

Q9NY91
MEPPDQCSQYMTSLL

RHOXF2B

1

P0C7M4
INPYMSSPCHIEMIL

RPL17

136

P18621
CPGDLREMISMYLPA

SOX1

336

O00570
MPEPRYVVSMGSCAN

NDUFS7

141

O75251
PSMGTLMGVYLPCLQ

SLC12A4

116

Q9UP95
PDSMKVLPVYMNCLL

SEC24D

836

O94855
HFGIVPLEAMYMQCP

ALG2

326

Q9H553
PLEAMYMQCPVIAVN

ALG2

331

Q9H553
PCMVVGTQNPFAFLM

SLC49A3

116

Q6UXD7
MNSPPGQYFSPLDCM

UCP3

246

P55916
IMCIFYMPTVNSLPE

TXNDC16

16

Q9P2K2
VLRPALPGTMMQCYL

TULP2

276

O00295
YESICNGVPMVMMPL

UGT1A10

376

Q9HAW8
MSCLDVMYQVYGPPQ

VGLL2

1

Q8N8G2
MMPYFCLDNNSPLPD

SLC7A1

311

P30825
LVGPQMFMDCSPQAL

SPOCD1

756

Q6ZMY3
IAEGCMQGMVPYLPE

TNPO2

421

O14787
GNMCTPQMPCSVIVY

WBP2NL

161

Q6ICG8
RPIMPNMVFVGGINC

UGT1A1

266

P22309
MCPLARQGDFYVPEM

TEX264

181

Q9Y6I9
PFTCAYGLVLQVPMM

SERPINE3

211

A8MV23
MEPPDQCSQYMTSLL

RHOXF2

1

Q9BQY4
YESICNGVPMVMMPL

UGT1A9

376

O60656
AIAEGCMQGMIPYLP

TNPO1

431

Q92973
PLSNSLMQPCYEPVM

ZC3H12B

746

Q5HYM0
MYMADSQCTSPGIPA

UACA

401

Q9BZF9
FDMTQCIGPNGYMEP

ZMYM2

546

Q9UBW7
GDVCEVQLMVYNPMP

TRAPPC9

596

Q96Q05
IYMQMLLCPDPAVSF

UBR4

2681

Q5T4S7
YESICNGVPMVMMPL

UGT1A7

376

Q9HAW7
YESICNGVPMVMMPL

UGT1A8

376

Q9HAW9
MIGPQALYMCTDINP

N6AMT1

66

Q9Y5N5