Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	TRIM2 WIPF1 PSG1 KIF26A HAP1 IFT74 APC2 TOGARAM2 KLC2 ARFGEF1 CORO1B FTCD KIF24 OPHN1 ALMS1 MAP1S MICALL2 IFT88 ANLN KIF13A FAM110C MAPK8IP2 PICK1	3.40e-05	1099	164	23	GO:0008092
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	TRIO KALRN ARFGEF1 ARHGEF17 DENND4B EIF2B2 FGD1 HERC2 RGL2	1.27e-04	231	164	9	GO:0005085
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR1 ITPR2	2.00e-04	3	164	2	GO:0005220
GeneOntologyBiologicalProcess	regulation of cell projection organization	DSCAM KALRN KIF26A HAP1 SRCIN1 CORO1B RET CSMD3 KIF24 ITPR1 ARHGAP4 TBC1D10B LIMK1 IFT88 PTPRS ANLN PTPRZ1 SKOR2 EIF2B2 NEURL1 PAK3 FAM110C GPRC5B	4.11e-07	863	165	23	GO:0031344
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	DSCAM KALRN KIF26A HAP1 SRCIN1 CORO1B RET CSMD3 KIF24 ITPR1 ARHGAP4 TBC1D10B LIMK1 IFT88 PTPRS ANLN PTPRZ1 SKOR2 EIF2B2 NEURL1 PAK3 GPRC5B	1.13e-06	846	165	22	GO:0120035
GeneOntologyBiologicalProcess	neuron projection development	DSCAM TRIO KALRN KIF26A HAP1 ARFGEF1 PDZD7 SRCIN1 RET CSMD3 OPHN1 ITPR1 ARHGAP4 LIMK1 ALMS1 MAP1S MICALL2 IFT88 PTPRS PTPRZ1 SKOR2 EIF2B2 NEURL1 PAK3 TMEM108 SCRIB MAPK8IP2 GPRC5B	1.18e-06	1285	165	28	GO:0031175
GeneOntologyBiologicalProcess	neuron development	DSCAM TRIO KALRN KIF26A HAP1 ARFGEF1 PDZD7 SRCIN1 RET CSMD3 OPHN1 ITPR1 ARHGAP4 LIMK1 ALMS1 MAP1S MICALL2 IFT88 PTPRS PTPRZ1 SKOR2 EIF2B2 NEURL1 PAK3 TMEM108 SCRIB MAPK8IP2 PICK1 GPRC5B	4.85e-06	1463	165	29	GO:0048666
GeneOntologyBiologicalProcess	postsynapse organization	FRMPD4 KALRN NLGN4Y SRCIN1 ZDHHC8 OPHN1 NLGN4X PTPRS NEURL1 PAK3 TMEM108 PICK1	8.61e-06	313	165	12	GO:0099173
GeneOntologyBiologicalProcess	regulation of postsynaptic neurotransmitter receptor internalization	HAP1 TAMALIN OPHN1 SCRIB PICK1	1.42e-05	39	165	5	GO:0099149
GeneOntologyBiologicalProcess	regulation of neuron projection development	DSCAM KALRN KIF26A HAP1 SRCIN1 RET CSMD3 ITPR1 ARHGAP4 LIMK1 PTPRS PTPRZ1 SKOR2 EIF2B2 PAK3 GPRC5B	3.39e-05	612	165	16	GO:0010975
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	DSCAM KALRN HAP1 CORO1B RET ITPR1 LIMK1 IFT88 ANLN PTPRZ1 EIF2B2 NEURL1 PAK3 GPRC5B	4.53e-05	494	165	14	GO:0031346
GeneOntologyBiologicalProcess	postsynaptic neurotransmitter receptor internalization	HAP1 TAMALIN OPHN1 SCRIB PICK1	5.38e-05	51	165	5	GO:0098884
GeneOntologyBiologicalProcess	postsynaptic endocytosis	HAP1 TAMALIN OPHN1 SCRIB PICK1	5.38e-05	51	165	5	GO:0140239
GeneOntologyBiologicalProcess	dendrite development	DSCAM KALRN SRCIN1 CSMD3 MAP1S PTPRS PTPRZ1 SKOR2 NEURL1 PAK3 MAPK8IP2	8.39e-05	335	165	11	GO:0016358
GeneOntologyBiologicalProcess	protein-containing complex localization	KALRN HAP1 IFT74 NUP88 TAMALIN OPHN1 IFT88 TMEM108 SCRIB PICK1	8.40e-05	278	165	10	GO:0031503
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	CHRNA6 TRIO HAP1 NLGN4Y GRIN2D OPHN1 USP8 NLGN4X PTPRS NEURL1 SORCS3 TMEM108 GABBR1 MAPK8IP2 PICK1 BEGAIN	8.72e-05	663	165	16	GO:0050804
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	CHRNA6 TRIO HAP1 NLGN4Y GRIN2D OPHN1 USP8 NLGN4X PTPRS NEURL1 SORCS3 TMEM108 GABBR1 MAPK8IP2 PICK1 BEGAIN	8.88e-05	664	165	16	GO:0099177
GeneOntologyBiologicalProcess	neurotransmitter receptor internalization	HAP1 TAMALIN OPHN1 SCRIB PICK1	1.00e-04	58	165	5	GO:0099590
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	DSCAM TRIO KALRN PDZD7 SRCIN1 RET OPHN1 ARHGAP4 LIMK1 MAP1S PTPRS PTPRZ1 SKOR2 EIF2B2 PAK3 SCRIB MAPK8IP2	1.08e-04	748	165	17	GO:0048667
GeneOntologyBiologicalProcess	territorial aggressive behavior	NLGN4Y NLGN4X	1.90e-04	3	165	2	GO:0002124
GeneOntologyBiologicalProcess	cell morphogenesis	DSCAM TRIO KALRN PDZD7 SRCIN1 CORO1B RET OPHN1 ITPR1 ARHGAP4 LIMK1 MAP1S IFT88 PTPRS PTPRZ1 SKOR2 EIF2B2 FGD1 PAK3 TMEM108 SCRIB MAPK8IP2	2.21e-04	1194	165	22	GO:0000902
GeneOntologyBiologicalProcess	metencephalon development	HAP1 NLGN4Y OPHN1 NLGN4X PTPRS SKOR2 SCRIB	2.35e-04	153	165	7	GO:0022037
GeneOntologyBiologicalProcess	neuron cell-cell adhesion	NLGN4Y RET NLGN4X	2.61e-04	16	165	3	GO:0007158
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	DSCAM TRIO KALRN SRCIN1 CORO1B RET OPHN1 ARHGAP4 LIMK1 MAP1S PTPRS PTPRZ1 SKOR2 EIF2B2 PAK3 TMEM108 MAPK8IP2	3.15e-04	819	165	17	GO:0120039
GeneOntologyBiologicalProcess	establishment of endothelial intestinal barrier	PTPRS TJP2 TJP3	3.15e-04	17	165	3	GO:0090557
GeneOntologyBiologicalProcess	cell projection morphogenesis	DSCAM TRIO KALRN SRCIN1 CORO1B RET OPHN1 ARHGAP4 LIMK1 MAP1S PTPRS PTPRZ1 SKOR2 EIF2B2 PAK3 TMEM108 MAPK8IP2	3.47e-04	826	165	17	GO:0048858
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane neurotransmitter receptor levels	KALRN HAP1 TAMALIN OPHN1 TMEM108 SCRIB PICK1	3.59e-04	164	165	7	GO:0099072
GeneOntologyBiologicalProcess	male courtship behavior	NLGN4Y NLGN4X	3.78e-04	4	165	2	GO:0008049
GeneOntologyCellularComponent	postsynapse	CHRNA6 FRMPD4 TRIO KALRN HAP1 NLGN4Y APC2 SRCIN1 GRIN2D ZDHHC8 TAMALIN OPHN1 ITPR1 RPL23 USP8 LIMK1 NLGN4X PTPRS PTPRZ1 EIF2B2 NEURL1 PAK3 SORCS3 TMEM108 SCRIB GABBR1 MAPK8IP2 PICK1 BEGAIN	2.27e-09	1018	167	29	GO:0098794
GeneOntologyCellularComponent	postsynaptic density	FRMPD4 KALRN NLGN4Y SRCIN1 GRIN2D TAMALIN ITPR1 RPL23 USP8 NLGN4X PTPRS PTPRZ1 NEURL1 PAK3 SORCS3 TMEM108 SCRIB MAPK8IP2 PICK1	3.90e-09	451	167	19	GO:0014069
GeneOntologyCellularComponent	neuron to neuron synapse	FRMPD4 KALRN NLGN4Y SRCIN1 GRIN2D SLC30A3 TAMALIN ITPR1 RPL23 USP8 NLGN4X PTPRS PTPRZ1 NEURL1 PAK3 SORCS3 TMEM108 SCRIB MAPK8IP2 PICK1	7.64e-09	523	167	20	GO:0098984
GeneOntologyCellularComponent	glutamatergic synapse	FRMPD4 TRIO KALRN NLGN4Y SRCIN1 CORO1B GRIN2D SLC30A3 ZDHHC8 TAMALIN PPM1H OPHN1 USP8 LIMK1 NLGN4X PTPRS PTPRZ1 NEURL1 PAK3 SORCS3 TMEM108 SCRIB GABBR1 PICK1 BEGAIN	8.17e-09	817	167	25	GO:0098978
GeneOntologyCellularComponent	asymmetric synapse	FRMPD4 KALRN NLGN4Y SRCIN1 GRIN2D TAMALIN ITPR1 RPL23 USP8 NLGN4X PTPRS PTPRZ1 NEURL1 PAK3 SORCS3 TMEM108 SCRIB MAPK8IP2 PICK1	9.68e-09	477	167	19	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	FRMPD4 KALRN NLGN4Y SRCIN1 GRIN2D TAMALIN ITPR1 RPL23 USP8 NLGN4X PTPRS PTPRZ1 NEURL1 PAK3 SORCS3 TMEM108 SCRIB MAPK8IP2 PICK1	2.26e-08	503	167	19	GO:0099572
GeneOntologyCellularComponent	exon-exon junction complex	CASC3 PNN THRAP3 SMG6	2.11e-05	21	167	4	GO:0035145
GeneOntologyCellularComponent	postsynaptic density membrane	NLGN4Y GRIN2D NLGN4X PTPRS PTPRZ1 SORCS3 TMEM108 SCRIB	3.91e-05	157	167	8	GO:0098839
GeneOntologyCellularComponent	dendrite	CASC3 FRMPD4 DSCAM HAP1 NLGN4Y SRCIN1 RET OPHN1 ITPR1 USP8 NLGN4X MAP1S PTPRZ1 NEURL1 TMEM108 TMEM151A GABBR1 PICK1 BEGAIN	5.83e-05	858	167	19	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CASC3 FRMPD4 DSCAM HAP1 NLGN4Y SRCIN1 RET OPHN1 ITPR1 USP8 NLGN4X MAP1S PTPRZ1 NEURL1 TMEM108 TMEM151A GABBR1 PICK1 BEGAIN	6.01e-05	860	167	19	GO:0097447
GeneOntologyCellularComponent	perinuclear region of cytoplasm	JCAD CASC3 KALRN HAP1 TRAIP APC2 WRNIP1 ARFGEF1 CORO1B SEC31A CMYA5 ZDHHC8 TAMALIN ITPR1 LIMK1 TMEM184A MAP1S NEURL1 PICK1	1.76e-04	934	167	19	GO:0048471
GeneOntologyCellularComponent	nuclear speck	CASC3 SETD1A IL16 PNN ZC3H18 CMYA5 PRX LIMK1 GCAT TREML1 THRAP3 EPAS1	1.87e-04	431	167	12	GO:0016607
GeneOntologyCellularComponent	postsynaptic specialization membrane	NLGN4Y GRIN2D NLGN4X PTPRS PTPRZ1 SORCS3 TMEM108 SCRIB	2.18e-04	201	167	8	GO:0099634
GeneOntologyCellularComponent	presynapse	CHRNA6 TRIO KALRN HAP1 NLGN4Y SRCIN1 GRIN2D SLC30A3 OPHN1 NECAP1 ITPR1 RPL23 NLGN4X PTPRS SCRIB GABBR1 PICK1 BEGAIN	2.67e-04	886	167	18	GO:0098793
GeneOntologyCellularComponent	somatodendritic compartment	CASC3 FRMPD4 DSCAM KALRN HAP1 NLGN4Y SRCIN1 RET OPHN1 ITPR1 USP8 NLGN4X MAP1S PTPRS PTPRZ1 NEURL1 TMEM108 TMEM151A GABBR1 MAPK8IP2 PICK1 BEGAIN	3.22e-04	1228	167	22	GO:0036477
GeneOntologyCellularComponent	symmetric, GABA-ergic, inhibitory synapse	NLGN4Y NLGN4X	3.77e-04	4	167	2	GO:0098983
GeneOntologyCellularComponent	postsynaptic membrane	CHRNA6 NLGN4Y GRIN2D TAMALIN NLGN4X PTPRS PTPRZ1 SORCS3 TMEM108 SCRIB GABBR1	4.28e-04	405	167	11	GO:0045211
GeneOntologyCellularComponent	glycinergic synapse	NLGN4Y NLGN4X EIF2B2	5.17e-04	20	167	3	GO:0098690
GeneOntologyCellularComponent	dendritic spine	FRMPD4 HAP1 OPHN1 USP8 PTPRZ1 NEURL1 GABBR1 PICK1	7.50e-04	242	167	8	GO:0043197
GeneOntologyCellularComponent	synaptic membrane	CHRNA6 NLGN4Y GRIN2D TAMALIN ITPR1 NLGN4X PTPRS PTPRZ1 SORCS3 TMEM108 SCRIB GABBR1 PICK1	8.43e-04	583	167	13	GO:0097060
GeneOntologyCellularComponent	neuron spine	FRMPD4 HAP1 OPHN1 USP8 PTPRZ1 NEURL1 GABBR1 PICK1	8.57e-04	247	167	8	GO:0044309
GeneOntologyCellularComponent	platelet dense tubular network membrane	ITPR1 ITPR2	2.20e-03	9	167	2	GO:0031095
GeneOntologyCellularComponent	lamellipodium	APC2 SRCIN1 CORO1B LIMK1 PTPRZ1 FGD1 SCRIB	2.55e-03	230	167	7	GO:0030027
GeneOntologyCellularComponent	centriole	HAP1 FTCD KIF24 ALMS1 IFT88 HERC2	2.63e-03	172	167	6	GO:0005814
HumanPheno	Impaired social interactions	FRMPD4 POLA1 TWNK EXTL3 NDUFV1 OPHN1 ITPR1 NLGN4X KMT5B	2.41e-05	129	63	9	HP:0000735
HumanPheno	Autistic behavior	SETD1A FRMPD4 TRIO IFT74 POLA1 APC2 TWNK EXTL3 FTCD GRIN2D NDUFV1 OPHN1 NECAP1 ITPR1 KMT2C LIMK1 NLGN4X ALMS1 KMT5B HERC2 GABBR1	3.41e-05	678	63	21	HP:0000729
HumanPheno	Reduced social responsiveness	FRMPD4 POLA1 VPS13C TWNK EXTL3 NDUFV1 OPHN1 ITPR1 NLGN4X KMT5B	3.64e-05	170	63	10	HP:0012760
HumanPheno	Diagnostic behavioral phenotype	SETD1A FRMPD4 TRIO IFT74 POLA1 APC2 TWNK PDZD7 EXTL3 FTCD GRIN2D NDUFV1 OPHN1 NECAP1 ITPR1 KMT2C LIMK1 NLGN4X ALMS1 KMT5B HERC2 GABBR1	4.53e-05	747	63	22	HP:0025783
HumanPheno	Vocal cord dysfunction	TRIM2 POLA1 RET PRX FH EPAS1	6.23e-05	57	63	6	HP:0031801
HumanPheno	Vocal cord paralysis	TRIM2 POLA1 RET PRX FH EPAS1	6.23e-05	57	63	6	HP:0001605
HumanPheno	Vocal cord paresis	TRIM2 POLA1 RET PRX FH EPAS1	6.23e-05	57	63	6	HP:0001604
HumanPheno	Weakness of the vocal cords	TRIM2 POLA1 RET PRX FH EPAS1	6.23e-05	57	63	6	HP:0001603
HumanPheno	Abnormal vocal cord morphology	TRIM2 POLA1 RET PRX FH EPAS1	9.18e-05	61	63	6	HP:0008777
HumanPheno	Abnormal nonverbal communicative behavior	FRMPD4 POLA1 TWNK NDUFV1 OPHN1 ITPR1 NLGN4X KMT5B	9.27e-05	119	63	8	HP:0000758
HumanPheno	Abnormal larynx morphology	AMER1 TRIM2 POLA1 EXTL3 RET PRX FH KAT6B EPAS1 ADAMTSL2	1.50e-04	201	63	10	HP:0025423
MousePheno	abnormal dendrite morphology	SETD1A KALRN SRCIN1 CMYA5 CSMD3 ZDHHC8 OPHN1 SKOR2 PAK3 TMEM108 HERC2 MAPK8IP2	1.51e-06	237	126	12	MP:0008143
MousePheno	abnormal neurite morphology	SETD1A TRIM2 DSCAM KALRN SRCIN1 CMYA5 CSMD3 ZDHHC8 PRX OPHN1 SKOR2 PAK3 TMEM108 HERC2 GABBR1 MAPK8IP2	2.23e-06	442	126	16	MP:0008415
Domain	PDZ	IL16 FRMPD4 PDZD7 TAMALIN PRX LIMK1 TJP2 SCRIB PICK1 TJP3	2.99e-07	141	156	10	PF00595
Domain	PDZ	IL16 FRMPD4 PDZD7 TAMALIN PRX LIMK1 TJP2 SCRIB PICK1 TJP3	4.70e-07	148	156	10	SM00228
Domain	-	IL16 FRMPD4 PDZD7 TAMALIN PRX LIMK1 TJP2 SCRIB PICK1 TJP3	5.32e-07	150	156	10	2.30.42.10
Domain	PDZ	IL16 FRMPD4 PDZD7 TAMALIN PRX LIMK1 TJP2 SCRIB PICK1 TJP3	5.66e-07	151	156	10	PS50106
Domain	PDZ	IL16 FRMPD4 PDZD7 TAMALIN PRX LIMK1 TJP2 SCRIB PICK1 TJP3	6.01e-07	152	156	10	IPR001478
Domain	NLGN4	NLGN4Y NLGN4X	6.93e-05	2	156	2	IPR030025
Domain	ZO	TJP2 TJP3	2.07e-04	3	156	2	IPR005417
Domain	InsP3_rcpt-bd	ITPR1 ITPR2	2.07e-04	3	156	2	IPR000493
Pathway	REACTOME_RHOA_GTPASE_CYCLE	TRIO KALRN ARHGEF17 OPHN1 ARHGAP4 ANLN TJP2 PCDH7	2.35e-05	142	117	8	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	TRIO KALRN ARHGEF17 OPHN1 ARHGAP4 ANLN TJP2 PCDH7	3.33e-05	149	117	8	M41805
Pathway	SIG_CHEMOTAXIS	ITPR1 ITPR2 ARHGAP4 LIMK1 PAK3	3.39e-05	45	117	5	M5193
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CUL4A JCAD CASC3 AMER1 TRIO IFT74 KLC2 CCDC85C RAB11FIP1 ARHGEF17 PPM1H C6orf132 USP8 TBC1D10B LIMK1 ALMS1 ANLN N4BP2 NEURL1 TJP2 SCRIB PPIP5K2 KIF13A RGL2 PCDH7 CEP170B	1.53e-13	861	171	26	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A CRYBG2 TRIO KALRN KIF26A TWNK CORO1B EXTL3 GRIN2D ZDHHC8 BAHD1 C6orf132 ITPR2 KMT2C ZNF263 MAP1S PTPRS PKD1 HERC2 RGL2 CEP170B PICK1 SMG6 TJP3	1.19e-09	1105	171	24	35748872
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	JCAD FRMPD4 TRIO KALRN NUP88 WRNIP1 KLC2 TACC2 SRCIN1 CORO1B ECHS1 NDUFV1 ITPR1 RPL23 LARP4B C1orf198 MAP1S TJP2 PAK3 THRAP3 CEP170B GABBR1 BEGAIN	1.06e-08	1139	171	23	36417873
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CASC3 DSCAM TRIO KALRN APC2 CORO1B SEC31A GRIN2D PPM1H ZNF263 ZKSCAN1 PTPRS N4BP2 PAK3 SCRIB HERC2 THRAP3 CEP170B MAPK8IP2 BEGAIN SMG6	1.32e-08	963	171	21	28671696
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CUL4A IL16 TRPS1 WRNIP1 OAS3 HIC2 ZC3H18 CLPX RAB11FIP1 GGCX NPM3 CCNT1 ARHGAP4 TBC1D10B LARP4B ALMS1 KMT5B GCAT NEURL1 SCRIB KAT6B CEP170B	3.48e-08	1116	171	22	31753913
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IGHV3-49 IL16 TRIO KALRN WRNIP1 KLC2 SRCIN1 CORO1B ARHGEF17 NDUFB5 NDUFV1 OPHN1 ITPR2 RPL23 MAP1S MGST3 PTPRS PTPRZ1 TJP2 SCRIB FH THRAP3 CEP170B MAPK8IP2	1.60e-07	1431	171	24	37142655
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	PNN KALRN NUP88 KLC2 TACC2 RAB11FIP1 ANKZF1 LARP4B ANLN TJP2 SCRIB KIF13A THRAP3 BEGAIN	2.24e-07	503	171	14	16964243
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JCAD DSCAM TRIO KALRN IFT74 APC2 TRPS1 ZBTB47 SEC31A EXTL3 FTCD CMYA5 NDUFB5 USP8 LIMK1 MAP1S IFT88 PKD1 SCRIB HERC2 MAPK8IP2 PICK1	3.92e-07	1285	171	22	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A KIF26A VPS13C HIC2 SRCIN1 ERMP1 BAHD1 KIAA1614 ARHGAP4 KMT2C DDHD1 PPIP5K2 KAT6B SMG6	4.11e-07	529	171	14	14621295
Pubmed	Global landscape of HIV-human protein complexes.	CUL4A CASC3 TRPS1 ARFGEF1 MCL1 ANKZF1 NPM3 CCNT1 ALMS1 HERC2 THRAP3 ALPP SMG6	4.82e-07	457	171	13	22190034
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SETD1A POLA1 TRPS1 NUP88 ARFGEF1 ZC3H18 ITPR2 CCNT1 TRIR KAT6B THRAP3	1.12e-06	341	171	11	32971831
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	JCAD AMER1 TRIO IFT74 VPS13C NUP88 KLC2 CCDC85C CORO1B C1orf198 ALMS1 GCAT N4BP2 TJP2 HERC2 PPIP5K2 CEP170B	1.20e-06	853	171	17	28718761
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	HAP1 VPS13C APC2 NDUFV1 ITPR2 TBC1D10B TJP2 HERC2 CEP170B GABBR1 MAPK8IP2 BEGAIN	1.64e-06	430	171	12	32581705
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	SRCIN1 GRIN2D ZDHHC8 PTPRZ1 TJP2 THRAP3 CEP170B GABBR1 BEGAIN	2.36e-06	231	171	9	16452087
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	PNN ZC3H18 C6orf132 RPL23 TRIR MGST3 ANLN PCDH7 THRAP3 SMG6	3.20e-06	307	171	10	37499664
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CASC3 TRIO VPS13C WRNIP1 CORO1B GGCX ITPR2 USP8 LARP4B ALMS1 ANLN N4BP2 DDHD1 TJP2 PPIP5K2	3.81e-06	733	171	15	34672954
Pubmed	Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.	WNT9B RET PKD1 SCRIB	3.85e-06	22	171	4	27582005
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CUL4A TRPS1 NUP88 CCDC85C TACC2 CLPX KIF24 ITPR1 MAP1S MICALL2 MGST3 ANLN ASXL2 SCRIB HERC2 THRAP3 CEP170B ALPP BEGAIN	4.58e-06	1155	171	19	20360068
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	JCAD KLC2 CCDC85C SRCIN1 CORO1B C6orf132 USP8 TBC1D10B C1orf198 ANLN TJP2 SCRIB FAM110C	4.98e-06	565	171	13	25468996
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	JCAD SETD1A APC2 RET PRX NPM3 C6orf132 LARP4B MAP1S TMEM151A GPRC5B	1.02e-05	430	171	11	35044719
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	TRIO KALRN NLGN4Y SRCIN1 GRIN2D NLGN4X PCDH7 CEP170B BEGAIN	1.15e-05	281	171	9	28706196
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SETD1A FRMPD4 ARHGEF17 ALMS1 HERC2 KAT6B	1.32e-05	104	171	6	9205841
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	JCAD AMER1 KLC2 CCDC85C RAB11FIP1 PPM1H USP8 ALMS1 MAP1S TJP2 CEP170B	1.43e-05	446	171	11	24255178
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TCF3 TACC2 SEC31A KIF24 ITPR1 RPL23 CCNT1 LARP4B TJP2 PPIP5K2 KAT6B SMG6	1.52e-05	536	171	12	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TCF3 TACC2 SEC31A KIF24 ITPR1 RPL23 CCNT1 LARP4B TJP2 PPIP5K2 KAT6B SMG6	1.58e-05	538	171	12	10512203
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	CASC3 APC2 WRNIP1 TACC2 CORO1B SEC31A ECHS1 IFT88 THRAP3 PICK1 ADAMTSL2 BEGAIN	2.34e-05	560	171	12	21653829
Pubmed	Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1.	IFT88 PKD1	2.40e-05	2	171	2	18285569
Pubmed	Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.	ITPR1 ITPR2	2.40e-05	2	171	2	15201137
Pubmed	Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.	NLGN4Y NLGN4X	2.40e-05	2	171	2	23183221
Pubmed	Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.	NLGN4Y NLGN4X	2.40e-05	2	171	2	24855039
Pubmed	Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.	ITPR1 ITPR2	2.40e-05	2	171	2	23582047
Pubmed	Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.	NLGN4Y NLGN4X	2.40e-05	2	171	2	37001827
Pubmed	Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.	ITPR1 ITPR2	2.40e-05	2	171	2	19120126
Pubmed	Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.	TRIO KALRN	2.40e-05	2	171	2	26858404
Pubmed	Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion.	FH EPAS1	2.40e-05	2	171	2	21695080
Pubmed	The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells.	PSG1 FOXP3	2.40e-05	2	171	2	27817017
Pubmed	Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease.	IFT88 PKD1	2.40e-05	2	171	2	25999403
Pubmed	Incorporating Functional Information in Tests of Excess De Novo Mutational Load.	TRIO KMT5B	2.40e-05	2	171	2	26235986
Pubmed	Unusually rapid evolution of Neuroligin-4 in mice.	NLGN4Y NLGN4X	2.40e-05	2	171	2	18434543
Pubmed	An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.	ITPR1 ITPR2	2.40e-05	2	171	2	18708078
Pubmed	Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.	NLGN4Y NLGN4X	2.40e-05	2	171	2	37080762
Pubmed	DHHC8-dependent PICK1 palmitoylation is required for induction of cerebellar long-term synaptic depression.	ZDHHC8 PICK1	2.40e-05	2	171	2	24068808
Pubmed	Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.	NLGN4Y NLGN4X	2.40e-05	2	171	2	29106499
Pubmed	Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.	NLGN4Y NLGN4X	2.40e-05	2	171	2	26456829
Pubmed	Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.	NLGN4Y NLGN4X	2.40e-05	2	171	2	24104404
Pubmed	MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3+ regulatory T cells.	MCL1 FOXP3	2.40e-05	2	171	2	32612106
Pubmed	A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.	NLGN4Y NLGN4X	2.40e-05	2	171	2	32243781
Pubmed	Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.	NLGN4Y NLGN4X	2.40e-05	2	171	2	22989184
Pubmed	Forkhead box p3+ regulatory T cell underlies male resistance to experimental type 2 autoimmune hepatitis.	FTCD FOXP3	2.40e-05	2	171	2	20232291
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	SETD1A PNN ZC3H18 CLPX CCNT1 PTPRS SCRIB HERC2 THRAP3	2.69e-05	313	171	9	38270169
Pubmed	A human MAP kinase interactome.	WIPF1 KIF26A SEC31A EXTL3 RPL23 KMT2C N4BP2 PAK3 HERC2 RGL2 EPAS1	3.15e-05	486	171	11	20936779
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	KALRN ARHGEF17 ARHGAP4 FGD1	3.65e-05	38	171	4	11756498
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	WIPF1 TRAIP EXTL3 GRIN2D PRX PKD1 KIF13A RGL2 GABBR1	3.96e-05	329	171	9	17474147
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	IL16 TRIO POLA1 TRPS1 SRCIN1 SEC31A NDUFB5 ARHGAP4 KMT2C ZKSCAN1 DENND4B SKOR2 ASXL2	3.99e-05	689	171	13	36543142
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CUL4A CASC3 TCF3 AMER1 TRIO NLGN4Y VPS13C TRPS1 CCDC85C SRCIN1 NDUFB5 PPM1H KMT2C TMEM184A PTPRS PAK3 KAT6B THRAP3 CEP170B SMG6	4.72e-05	1489	171	20	28611215
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	CASC3 TCF3 AMER1 WRNIP1 CCDC85C IER5 SEC31A RAB11FIP1 ANKZF1 LARP4B C1orf198 EIF2B2 TJP2 THRAP3 BEGAIN TJP3	5.84e-05	1038	171	16	26673895
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	KALRN ARHGEF17 ARHGAP4 FGD1	5.99e-05	43	171	4	12376548
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	JCAD PNN CORO1B LARP4B TJP2 SCRIB PCDH7 THRAP3	6.81e-05	274	171	8	34244482
Pubmed	Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.	ITPR1 ITPR2	7.19e-05	3	171	2	10874040
Pubmed	Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.	ITPR1 ITPR2	7.19e-05	3	171	2	20395455
Pubmed	Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.	TRIO KALRN	7.19e-05	3	171	2	31801062
Pubmed	Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.	ITPR1 ITPR2	7.19e-05	3	171	2	17437169
Pubmed	HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia.	USP8 EPAS1	7.19e-05	3	171	2	24378640
Pubmed	Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.	ITPR1 ITPR2	7.19e-05	3	171	2	18547250
Pubmed	Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.	ITPR1 ITPR2	7.19e-05	3	171	2	36350267
Pubmed	Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.	ITPR1 ITPR2	7.19e-05	3	171	2	32320395
Pubmed	The versatility and universality of calcium signalling.	ITPR1 ITPR2	7.19e-05	3	171	2	11413485
Pubmed	Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	7.19e-05	3	171	2	26009177
Pubmed	Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha.	PTPRZ1 EPAS1	7.19e-05	3	171	2	20224786
Pubmed	Receptor-activated single channels in intact human platelets.	ITPR1 ITPR2	7.19e-05	3	171	2	1693919
Pubmed	Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.	ITPR1 ITPR2	7.19e-05	3	171	2	23955339
Pubmed	Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.	ITPR1 ITPR2	7.19e-05	3	171	2	31979185
Pubmed	Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease.	ITPR1 PKD1	7.19e-05	3	171	2	19854836
Pubmed	Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.	ITPR1 ITPR2	7.19e-05	3	171	2	24904548
Pubmed	Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.	TJP2 TJP3	7.19e-05	3	171	2	19538286
Pubmed	Expression of E2A in mid-secretory endometrium of women suffering from recurrent miscarriage.	TCF3 FOXP3	7.19e-05	3	171	2	29270752
Pubmed	Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion.	TJP2 TJP3	7.19e-05	3	171	2	25486565
Pubmed	Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.	ITPR1 ITPR2	7.19e-05	3	171	2	9858485
Pubmed	Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.	IFT88 PKD1	7.19e-05	3	171	2	12514735
Pubmed	Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.	ITPR1 ITPR2	7.19e-05	3	171	2	9808793
Pubmed	Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.	NLGN4Y NLGN4X	7.19e-05	3	171	2	32011705
Pubmed	Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.	ITPR1 ITPR2	7.19e-05	3	171	2	18194433
Pubmed	IP3 receptors regulate vascular smooth muscle contractility and hypertension.	ITPR1 ITPR2	7.19e-05	3	171	2	27777977
Pubmed	Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.	ITPR1 ITPR2	7.19e-05	3	171	2	17581770
Pubmed	Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.	ITPR1 ITPR2	7.19e-05	3	171	2	18241669
Pubmed	Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.	ITPR1 ITPR2	7.19e-05	3	171	2	19068129
Pubmed	Analysis of the neuroligin 4Y gene in patients with autism.	NLGN4Y NLGN4X	7.19e-05	3	171	2	18628683
Pubmed	Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	7.19e-05	3	171	2	17327232
Pubmed	Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.	ITPR1 ITPR2	7.19e-05	3	171	2	23223241
Pubmed	Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.	ITPR1 ITPR2	7.19e-05	3	171	2	16014380
Pubmed	The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.	IFT88 PKD1	7.19e-05	3	171	2	16567633
Pubmed	Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.	ITPR1 ITPR2	7.19e-05	3	171	2	17890015
Pubmed	Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.	ITPR1 ITPR2	7.19e-05	3	171	2	23983250
Pubmed	Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.	NLGN4Y NLGN4X	7.19e-05	3	171	2	21282647
Pubmed	Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.	ITPR1 ITPR2	7.19e-05	3	171	2	20427533
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A PNN IFT74 CCDC85C CORO1B KMT2C ALMS1 ANLN TJP2 SCRIB THRAP3	9.35e-05	549	171	11	38280479
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	CUL4A TRPS1 ARFGEF1 CCNT1 TRIR SCRIB THRAP3	9.95e-05	215	171	7	35973513
Pubmed	Genes, plasticity and mental retardation.	OPHN1 LIMK1 PAK3	1.07e-04	19	171	3	18329113
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SETD1A CRYBG2 ZC3H18 ZNF831 NPM3 KMT2C LARP4B TRIR ALMS1 N4BP2	1.18e-04	469	171	10	27634302
Pubmed	PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.	SEC31A MICALL2 ANLN	1.25e-04	20	171	3	32079660
Interaction	CTNNB1 interactions	CUL4A JCAD TCF3 AMER1 SPN APC2 KLC2 ARFGEF1 CCDC85C SRCIN1 CORO1B GRIN2D RET NDUFV1 RPL23 USP8 LMBR1L ANLN PTPRZ1 PKD1 TJP2 ASXL2 SCRIB HERC2 THRAP3 EPAS1 PICK1	4.58e-08	1009	164	27	int:CTNNB1
Interaction	MAPRE3 interactions	CUL4A TRIO IFT74 TRAIP APC2 TACC2 KIF24 C6orf132 LARP4B MAP1S CEP170B PICK1	4.17e-07	230	164	12	int:MAPRE3
Interaction	CLK2 interactions	CASC3 PNN TACC2 ZC3H18 CCNT1 ZNF263 LARP4B ZNF837 HERC2 THRAP3	4.61e-06	195	164	10	int:CLK2
Interaction	BICD1 interactions	JCAD DSCAM IFT74 CORO1B SEC31A MICALL2 ANLN N4BP2 TJP2 HERC2 CEP170B	6.65e-06	250	164	11	int:BICD1
Interaction	YWHAH interactions	JCAD CASC3 AMER1 PNN TRIO IFT74 KLC2 CCDC85C TWNK ERMP1 RAB11FIP1 ARHGEF17 PPM1H C6orf132 USP8 TBC1D10B ALMS1 LMBR1L ANLN TJP2 SCRIB PPIP5K2 RGL2 CEP170B	1.01e-05	1102	164	24	int:YWHAH
Interaction	CLK3 interactions	CASC3 PNN ZC3H18 CCNT1 ZNF263 LARP4B ANLN SCRIB THRAP3 FOXP3	1.33e-05	220	164	10	int:CLK3
Interaction	NLGN3 interactions	PSG1 NLGN4Y APC2 NLGN4X MAP1S PICK1 ALPP	1.65e-05	99	164	7	int:NLGN3
Interaction	YWHAG interactions	CUL4A JCAD CASC3 AMER1 PNN KLC2 CCDC85C RAB11FIP1 ARHGEF17 PPM1H C6orf132 USP8 TBC1D10B ALMS1 ANLN N4BP2 TJP2 SCRIB PPIP5K2 FH KIF13A RGL2 PCDH7 THRAP3 CEP170B	2.66e-05	1248	164	25	int:YWHAG
Cytoband	11q13.2	KLC2 CORO1B KMT5B TMEM151A	2.92e-05	47	171	4	11q13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr11q13	KLC2 CORO1B ARHGEF17 NDUFV1 B3GNT6 KMT5B TMEM151A SPINDOC	3.25e-04	454	171	8	chr11q13
GeneFamily	PDZ domain containing	IL16 FRMPD4 PDZD7 TAMALIN PRX LIMK1 TJP2 SCRIB PICK1 TJP3	2.09e-08	152	106	10	1220
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR1 ITPR2	1.02e-04	3	106	2	297
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TRIO KALRN ARHGEF17 FGD1	6.08e-04	66	106	4	722
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A KMT2C KMT5B	1.03e-03	34	106	3	487
GeneFamily	CD molecules\|V-set domain containing\|Pregnancy specific glycoproteins	PSG1 PSG7	1.81e-03	11	106	2	1315
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF26A KIF24 KIF13A	2.48e-03	46	106	3	622
GeneFamily	Fibronectin type III domain containing	DSCAM KALRN CMYA5 PTPRS PTPRZ1	2.52e-03	160	106	5	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	DSCAM TRIO KALRN SIGLEC16 PTPRS	2.59e-03	161	106	5	593
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	JCAD TRIM2 DSCAM PNN TRIO KALRN IER5 SRCIN1 ERMP1 TAMALIN OPHN1 ITPR2 ALMS1 ZKSCAN1 PTPRZ1 DDHD1 PAK3 TMEM108 TMEM151A KIF13A PCDH7	8.33e-06	1102	168	21	M2369
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	JCAD TRIM2 DSCAM PNN TRIO KALRN IER5 SRCIN1 ERMP1 TAMALIN OPHN1 ITPR2 ALMS1 ZKSCAN1 PTPRZ1 DDHD1 PAK3 TMEM108 TMEM151A KIF13A PCDH7	1.12e-05	1124	168	21	MM1070
Coexpression	MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP	RAB11FIP1 PRX CEP170B GABBR1 MAPK8IP2 PICK1	2.08e-05	87	168	6	M945
Coexpression	GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN	ADGRG3 VPS13C RAB11FIP1 ZDHHC8 PTPRZ1 KAT6B KIF13A GABBR1	2.12e-05	179	168	8	M6689
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#5_top-relative-expression-ranked_500	CRYBG2 TRIM2 RET C6orf132 FAM110C TJP3	2.01e-05	73	162	6	gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_500_k5
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM HAP1 TACC2 CMYA5 CSMD3 OPHN1 NLGN4X MICALL2 PTPRZ1 SORCS3 KIF13A	2.91e-10	196	171	11	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM HAP1 TACC2 CMYA5 CSMD3 OPHN1 NLGN4X MICALL2 PTPRZ1 SORCS3 KIF13A	2.91e-10	196	171	11	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGIF2 SPN ZNF366 TWNK RET RAB11FIP1 TAMALIN SHE	2.67e-07	166	171	8	c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNN VPS13C SEC31A CMYA5 KMT5B PCDH7 THRAP3 ADAMTSL2	4.17e-07	176	171	8	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM HAP1 TACC2 CSMD3 OPHN1 NLGN4X PTPRZ1 KIF13A	7.45e-07	190	171	8	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Tfh\|blood / Manually curated celltypes from each tissue	IFT74 KLC2 ZNF831 ITPR1 GCAT NEURL1 SPINDOC	5.23e-06	175	171	7	d7e24ac683ff36f7ce3d1151353d3d4a6f2b63bf
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	JCAD KIF26A WNT9B TAMALIN SHE EPAS1 GPRC5B	7.80e-06	186	171	7	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	droplet-Trachea-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAB11FIP1 C6orf132 TMEM184A MGST3 PTPRZ1 FAM110C TJP3	8.96e-06	190	171	7	0114cf48612d78c3ada4d8a05850501fef6892c5
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAB11FIP1 C6orf132 TMEM184A MGST3 PTPRZ1 FAM110C TJP3	8.96e-06	190	171	7	01e7747547ea1f3049a11a1717565ba71dd52bdc
ToppCell	droplet-Trachea-nan-3m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB11FIP1 C6orf132 TMEM184A MGST3 PTPRZ1 FAM110C TJP3	8.96e-06	190	171	7	e647f9a2dcf7f2dffef53c45bbe171416518fd59
ToppCell	droplet-Trachea-nan-3m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB11FIP1 C6orf132 TMEM184A MGST3 PTPRZ1 FAM110C TJP3	8.96e-06	190	171	7	434de72dde09644efbddcaa643a4a3eaf5f643bf
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG2 TACC2 CMYA5 RAB11FIP1 C6orf132 TMEM184A TJP3	9.92e-06	193	171	7	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	IPF-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	IL16 PRX OPHN1 NLGN4X TMEM108 EPAS1 ADAMTSL2	1.10e-05	196	171	7	8f0f72ead06abe02b575e443552eacc2151077ef
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TWNK RAB11FIP1 ARHGEF17 C6orf132 TMEM184A TJP2 CEP170B	1.10e-05	196	171	7	9554ac6eb5f381bcde3ba40c32aa3fc340974540
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	PNN VPS13C MCL1 OAS3 TAMALIN KMT2C TRIR	1.13e-05	197	171	7	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IFT74 TGFBR3L TACC2 CSMD3 PTPRZ1 PCDH7 TJP3	1.13e-05	197	171	7	b8dc192fc98428bbb701cc2ea57fc8ad93397785
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD4 KALRN CSMD3 ITPR1 PKD1 PAK3 DPY19L2P1	1.17e-05	198	171	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD KALRN ZNF366 TAMALIN PRX SHE EPAS1	1.17e-05	198	171	7	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD4 KALRN CSMD3 ITPR1 PAK3 PCDH7 DPY19L2P1	1.17e-05	198	171	7	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM TACC2 CSMD3 OPHN1 PCDH7 GABBR1 GPRC5B	1.21e-05	199	171	7	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM TACC2 CMYA5 CSMD3 OPHN1 KIF13A PCDH7	1.21e-05	199	171	7	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM TACC2 CSMD3 OPHN1 PCDH7 GABBR1 GPRC5B	1.21e-05	199	171	7	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	TRIM2 TRPS1 CMYA5 PPM1H PTPRS SH3RF2 PTPRZ1	1.25e-05	200	171	7	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM TACC2 CSMD3 OPHN1 PCDH7 GABBR1 GPRC5B	1.25e-05	200	171	7	ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-5\|TCGA-Adrenal / Sample_Type by Project: Shred V9	TGFBR3L RET KIAA1614 NEURL1 TMEM151A BEGAIN	1.33e-05	134	171	6	d4b175257c47916ed90cdb5c555c2b26530ce8d5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRMPD4 CSMD3 NLGN4X SH3RF2 NEURL1 FOXP3	1.44e-05	136	171	6	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TACC2 CMYA5 PTPRZ1 SORCS3 KIF13A GABBR1	3.02e-05	155	171	6	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CRYBG2 KALRN ZNF831 ZNF837 SPINDOC FOXP3	3.13e-05	156	171	6	84f01419d8c116714e8c8c857c4d153a755b7867
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD KALRN ZNF366 POLA1 TAMALIN EPAS1	3.13e-05	156	171	6	f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CRYBG2 KALRN ZNF831 ZNF837 SPINDOC FOXP3	3.13e-05	156	171	6	2285be9746d0d0f62a488b9c64fa67a834758dd7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 POLA1 TAMALIN SHE EPAS1 GPRC5B	4.43e-05	166	171	6	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HAP1 SRCIN1 CMYA5 PPM1H ITPR2 KMT2C	4.74e-05	168	171	6	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	JCAD KIF26A WNT9B TAMALIN SHE GPRC5B	4.74e-05	168	171	6	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	JCAD NLGN4Y ZNF831 PAK3 SHE FOXP3	4.74e-05	168	171	6	435b2f238fbb3f50427e8cdecf2220615015153c
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	WIPF1 NLGN4X MICALL2 PTPRZ1 SORCS3 MAPK8IP2	4.90e-05	169	171	6	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAP1 CMYA5 ZNF831 ITPR2 NEURL1 PCDH7	5.06e-05	170	171	6	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	metastatic_Brain-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	SPN TRPS1 ERMP1 TAMALIN NPM3 SPINDOC	5.23e-05	171	171	6	0d14bc9688c427ba2265984987dc3eea195b19eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 TAMALIN PRX SHE EPAS1 BEGAIN	5.58e-05	173	171	6	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF2 DSCAM TRAIP ALMS1 TREML1 TJP3	5.58e-05	173	171	6	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CRYBG2 KALRN KLC2 GGCX LIMK1 PKD1	5.76e-05	174	171	6	a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF24 NLGN4X ANLN PTPRZ1 TJP2 GPRC5B	5.94e-05	175	171	6	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF24 NLGN4X ANLN PTPRZ1 TJP2 GPRC5B	5.94e-05	175	171	6	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF24 NLGN4X ANLN PTPRZ1 TJP2 GPRC5B	5.94e-05	175	171	6	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF24 NLGN4X ANLN PTPRZ1 TJP2 GPRC5B	5.94e-05	175	171	6	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JCAD KIF26A NLGN4X SHE EPAS1 GPRC5B	6.33e-05	177	171	6	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	JCAD ADGRG3 KALRN RET CMYA5 GPRC5B	6.73e-05	179	171	6	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PHLDA3 TAMALIN SHE EPAS1 ADAMTSL2	6.73e-05	179	171	6	ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PHLDA3 TAMALIN SHE EPAS1 ADAMTSL2	6.73e-05	179	171	6	d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	JCAD KALRN TAMALIN PRX OPHN1 EPAS1	6.94e-05	180	171	6	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	severe-CD8+_T_naive\|World / disease stage, cell group and cell class	IPPK TRIM2 ANKZF1 IGLV9-49 ZDHHC8 CCNT1	7.16e-05	181	171	6	69eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 KIF26A HAP1 WNT9B NEURL1 PAK3	7.16e-05	181	171	6	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SPN KALRN PHLDA3 MGST3 LPL PCDH7	7.38e-05	182	171	6	a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAP1 PPM1H PRX MICALL2 PTPRZ1 SORCS3	8.08e-05	185	171	6	11c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	PNN VPS13C ERMP1 CCNT1 DDHD1 DENND4B	8.08e-05	185	171	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRCIN1 CMYA5 TAMALIN ITPR2 KMT2C PAK3	8.08e-05	185	171	6	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	JCAD TAMALIN PRX NLGN4X SHE EPAS1	8.08e-05	185	171	6	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHLDA3 SRCIN1 C1orf198 NLGN4X PTPRZ1 LPL	8.08e-05	185	171	6	f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell	5'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHLDA3 SRCIN1 C1orf198 NLGN4X PTPRZ1 LPL	8.08e-05	185	171	6	317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD TAMALIN SH3RF2 SHE EPAS1 GPRC5B	8.08e-05	185	171	6	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHLDA3 SRCIN1 C1orf198 NLGN4X PTPRZ1 LPL	8.08e-05	185	171	6	7bb8fdfe04f85d25056380ec58222366de323a21
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast\|bone_marrow / Manually curated celltypes from each tissue	KALRN TRAIP ARHGEF17 GCAT ANLN TREML1	8.08e-05	185	171	6	a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C MCL1 CSMD3 KIF24 KMT2C SORCS3	8.32e-05	186	171	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Control-Endothelial_cells-Endothelial_cells_(other)\|Control / group, cell type (main and fine annotations)	JCAD KALRN ZNF366 TAMALIN PRX EPAS1	8.32e-05	186	171	6	c6075fe84226b370c5139066793844ad33ae2db1
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	PNN VPS13C ERMP1 ITPR2 CCNT1 DDHD1	8.32e-05	186	171	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD KALRN ZNF366 WNT9B TAMALIN EPAS1	8.57e-05	187	171	6	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD KALRN ZNF366 POLA1 SHE EPAS1	8.57e-05	187	171	6	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	JCAD ZNF366 TAMALIN PRX NLGN4X EPAS1	8.57e-05	187	171	6	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C ARFGEF1 ITPR1 KMT2C DDHD1 SMG6	8.82e-05	188	171	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	KALRN MAPKAPK5-AS1 PRX OPHN1 EPAS1 ADAMTSL2	8.82e-05	188	171	6	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	Endothelial-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	KALRN KIF26A HIC2 ARHGEF17 SHE GABBR1	8.82e-05	188	171	6	ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 WNT9B ERMP1 C6orf132 GPRC5B TJP3	8.82e-05	188	171	6	315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYBG2 C6orf132 PTPRZ1 FAM110C EPAS1 TJP3	9.09e-05	189	171	6	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYBG2 C6orf132 PTPRZ1 FAM110C EPAS1 TJP3	9.09e-05	189	171	6	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAN1A1 KALRN SLC30A3 ITPR1 PCDH7 DPY19L2P1	9.09e-05	189	171	6	a75226616340045b581d08429d2e123e041dee55
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	PPM1H ITPR1 ITPR2 TMEM108 PCDH7 EPAS1	9.09e-05	189	171	6	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF26A APC2 RET SKOR2 TMEM108 MAPK8IP2	9.09e-05	189	171	6	cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	ZNF366 TAMALIN PRX NLGN4X SHE EPAS1	9.35e-05	190	171	6	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ADGRG3 MAN1A1 KALRN RET CMYA5 RAB11FIP1	9.35e-05	190	171	6	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD KALRN TAMALIN PRX EPAS1 ADAMTSL2	9.35e-05	190	171	6	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM2 FRMPD4 ERMP1 C6orf132 PAK3 TMEM151A	9.35e-05	190	171	6	c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD TAMALIN SH3RF2 SHE EPAS1 GPRC5B	9.35e-05	190	171	6	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM2 FRMPD4 ERMP1 C6orf132 PAK3 TMEM151A	9.35e-05	190	171	6	d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRG3 TRIM2 NLGN4Y ERMP1 PPM1H SORCS3	9.63e-05	191	171	6	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HAP1 SRCIN1 TAMALIN ITPR2 ANLN PAK3	9.63e-05	191	171	6	54f07e4de61735051498846afb44b1798bed8144
ToppCell	droplet-Tongue-nan-3m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 ERMP1 CLPX RAB11FIP1 ITPR2 EPAS1	9.63e-05	191	171	6	abdd93b2313e635f75a750d051a6a01ddc4e2df9
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ZNF366 TRPS1 RAB11FIP1 PPM1H SH3RF2 PAK3	9.91e-05	192	171	6	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD KALRN ZNF366 PRX SHE EPAS1	9.91e-05	192	171	6	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C MCL1 PPM1H ITPR2 KMT2C KMT5B	1.02e-04	193	171	6	a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPS1 RAB11FIP1 C6orf132 TMEM184A CEP170B TJP3	1.02e-04	193	171	6	22ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD KALRN ZNF366 PRX SHE EPAS1	1.02e-04	193	171	6	52e918884877b6659cdca0496390e440f73694a9
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERMP1 RAB11FIP1 PPM1H MGST3 TJP2 FAM110C	1.05e-04	194	171	6	1531dcace28a14bd700e909a027426a8cee20337
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ERMP1 C1orf198 ANLN TMEM151A GPRC5B	1.05e-04	194	171	6	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 WNT9B TACC2 CMYA5 PCDH7 TJP3	1.05e-04	194	171	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD KALRN ZNF366 TAMALIN SHE EPAS1	1.05e-04	194	171	6	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD DSCAM ZNF366 PRX SHE EPAS1	1.05e-04	194	171	6	74a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-IPC_like-IPCs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	RPL23 PTPRS PAK3 TMEM108 ADAMTSL2 GPRC5B	1.05e-04	194	171	6	2378a98452f6ec33870eeb994b8b812e9b507f4c
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	ARHGEF17 NEURL1 PAK3 TMEM151A MAPK8IP2 BEGAIN	1.05e-04	194	171	6	b6488bc3a8905e926ad298332963e1bbaf010046
ToppCell	Endothelial-endothelial_cell_of_vein\|World / Lineage, Cell type, age group and donor	JCAD KALRN WNT9B TAMALIN SHE EPAS1	1.05e-04	194	171	6	3cbd9622a68e89add90e589867d88c83c5a33476
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 WNT9B TACC2 CMYA5 PCDH7 TJP3	1.05e-04	194	171	6	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	ARHGEF17 NEURL1 PAK3 TMEM151A MAPK8IP2 BEGAIN	1.05e-04	194	171	6	1e1f4139ad584f493d75a9b7f1568eca4653c5a2
Computational	Genes in the cancer module 11.	TRIM2 HAP1 PSG7 APC2 TACC2 NECAP1 ITPR1 SLC22A18AS PTPRZ1 LPL NEURL1 PKD1 KAT6B EPAS1 GABBR1 MAPK8IP2 GPRC5B	4.05e-05	540	112	17	MODULE_11
Computational	Genes in the cancer module 100.	TRIM2 PSG7 APC2 TACC2 NECAP1 ITPR1 SLC22A18AS PTPRZ1 LPL NEURL1 PKD1 KAT6B EPAS1 GABBR1 MAPK8IP2 GPRC5B	1.54e-04	544	112	16	MODULE_100
Computational	Genes in the cancer module 66.	TRIM2 PSG7 APC2 TACC2 NECAP1 ITPR1 SLC22A18AS PTPRZ1 LPL NEURL1 PKD1 KAT6B EPAS1 GABBR1 MAPK8IP2 GPRC5B	1.83e-04	552	112	16	MODULE_66
Computational	Neighborhood of TNFRSF25	PSG1 TACC2 EXTL3 CLPX SLC30A3 BAHD1 ITPR2 PTPRS NEURL1 ADAMTSL2	4.48e-04	266	112	10	MORF_TNFRSF25
Computational	CNS genes.	TRIM2 PSG7 APC2 TACC2 NECAP1 ITPR1 SLC22A18AS LPL NEURL1 PKD1 KAT6B EPAS1 GABBR1 MAPK8IP2 GPRC5B	5.21e-04	546	112	15	MODULE_137
Drug	Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; HL60; HT_HG-U133A	IPPK SETD1A TGIF2 SPN OAS3 HIC2 BAHD1 GGCX ITPR2 CCNT1 KAT6B	2.02e-07	196	165	11	1864_DN
Drug	Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; MCF7; HT_HG-U133A	TRIM2 FRMPD4 DSCAM ARFGEF1 MCL1 SLC30A3 BAHD1 ITPR1 SORCS3 PICK1	1.38e-06	191	165	10	4791_UP
Drug	Colistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A	TRIM2 DSCAM KALRN MCL1 OAS3 ARHGEF17 SLC30A3 BAHD1 ITPR1 LARP4B	1.83e-06	197	165	10	4796_UP
Drug	Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A	CHRNA6 TCF3 SPN TRAIP ITPR1 CCNT1 ZKSCAN1 PICK1 SMG6	1.20e-05	193	165	9	3845_UP
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A	SPN HAP1 TRAIP OAS3 NPM3 SLC22A18AS LIMK1 NEURL1 FGD1	1.25e-05	194	165	9	3354_DN
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A	SETD1A TRIM2 TRAIP NPM3 LIMK1 ALMS1 ZKSCAN1 PTPRS PICK1	1.31e-05	195	165	9	3755_DN
Drug	Tranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A	SETD1A TRIO SPN POLM OAS3 ARHGAP4 PTPRS NEURL1 TJP3	1.36e-05	196	165	9	2248_DN
Drug	Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; PC3; HG-U133A	TCF3 TRIO ARFGEF1 ERMP1 CPOX ALMS1 IFT88 FH CEP170B	1.36e-05	196	165	9	1948_DN
Drug	Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A	SPN HAP1 EXTL3 SLC30A3 BAHD1 NPM3 ITPR2 CCNT1 SLC22A18AS	1.42e-05	197	165	9	2259_DN
Drug	Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A	TGIF2 TWNK TACC2 EXTL3 ANKZF1 ITPR1 TBC1D10B DENND4B FGD1	1.42e-05	197	165	9	7138_DN
Drug	Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A	SETD1A TCF3 DSCAM SPN HAP1 HIC2 ARHGEF17 NPM3 FGD1	1.48e-05	198	165	9	5243_DN
Drug	Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; HL60; HT_HG-U133A	IL16 VPS13C KLC2 MCL1 FTCD SLC30A3 NEURL1 KIF13A CEP170B	1.48e-05	198	165	9	2725_UP
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A	SETD1A WIPF1 TRIO PSG1 PHLDA3 MCL1 BAHD1 ITPR1 PCDH7	1.54e-05	199	165	9	4313_DN
Drug	AC1L9LT0	APC2 GRIN2D LIMK1 TJP2 SCRIB PICK1 TJP3	3.24e-05	123	165	7	CID000448294
Drug	cytochalasin B; Up 200; 20.8uM; MCF7; HT_HG-U133A_EA	CASC3 TCF3 TRIM2 TRIO VPS13C MCL1 ANKZF1 NPM3	3.94e-05	173	165	8	1122_UP
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CUL4A DSCAM TRPS1 PHLDA3 RET LARP4B FH KAT6B	4.45e-05	176	165	8	7499_DN
Drug	Ptca	POLA1 RET	5.22e-05	2	165	2	CID000443032
Drug	ICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A	MAN1A1 DSCAM PHLDA3 TWNK RET ANKZF1 IFT88 KAT6B	6.82e-05	187	165	8	6955_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A	TCF3 TRAIP IER5 HIC2 RET ITPR1 ITPR2 EPAS1	7.63e-05	190	165	8	3966_DN
Drug	Salbutamol [18559-94-9]; Down 200; 16.8uM; PC3; HT_HG-U133A	IPPK TGIF2 TRIM2 SPN PPM1H ITPR2 CCNT1 GPRC5B	7.91e-05	191	165	8	7376_DN
Drug	3'-deoxythymidine	TRIO POLM POLA1 SMG6 FOXP3	8.06e-05	61	165	5	CID000005280
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	IFT74 HIC2 RET RPL23 ALMS1 MICALL2 PPIP5K2 TJP3	8.21e-05	192	165	8	993_DN
Drug	Berberine chloride [633-65-8]; Down 200; 10.8uM; HL60; HG-U133A	MAN1A1 RAB11FIP1 ANKZF1 LARP4B ALMS1 PPIP5K2 FH CEP170B	8.21e-05	192	165	8	1778_DN
Drug	Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT_HG-U133A	SETD1A DSCAM HAP1 POLM OAS3 EXTL3 NPM3 ARHGAP4	8.82e-05	194	165	8	3526_UP
Drug	Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; PC3; HT_HG-U133A	IPPK KLC2 MCL1 HIC2 EXTL3 RAB11FIP1 GGCX FH	8.82e-05	194	165	8	1823_UP
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A	TCF3 MAN1A1 RET ANKZF1 ALMS1 IFT88 PPIP5K2 KAT6B	9.14e-05	195	165	8	6938_DN
Drug	Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	ARHGEF17 SLC30A3 BAHD1 ARHGAP4 ALMS1 PTPRS NEURL1 PCDH7	9.47e-05	196	165	8	3314_UP
Drug	Atracurium besylate [64228-81-5]; Down 200; 3.2uM; MCF7; HT_HG-U133A	TRIM2 DSCAM SPN CCDC85C ITPR2 RPL23 MAP1S ZKSCAN1	9.47e-05	196	165	8	7477_DN
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	TRIO PHLDA3 ARFGEF1 MCL1 NPM3 ALMS1 FH EPAS1	9.47e-05	196	165	8	1054_DN
Drug	LY294002; Down 200; 10uM; MCF7; HT_HG-U133A	TCF3 TRIM2 OAS3 CPOX RET SLC22A18AS FGD1 BEGAIN	9.47e-05	196	165	8	5937_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A	CUL4A TCF3 TGIF2 HIC2 ITPR1 LARP4B DENND4B KAT6B	9.47e-05	196	165	8	2035_DN
Drug	Allantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A	SETD1A CRYBG2 WIPF1 HAP1 HIC2 ARHGEF17 PRX ALMS1	9.47e-05	196	165	8	5052_UP
Drug	Acacetin [480-44-4]; Down 200; 14uM; PC3; HT_HG-U133A	CRYBG2 POLM TRAIP CCDC85C ITPR1 LMBR1L PICK1 SMG6	9.47e-05	196	165	8	3767_DN
Drug	Clozapine [5786-21-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	TGIF2 SPN VPS13C CCDC85C MCL1 TACC2 NPM3 MAP1S	9.81e-05	197	165	8	2644_DN
Drug	Cyclacillin [3485-14-1]; Down 200; 11.8uM; PC3; HT_HG-U133A	CRYBG2 TCF3 TRIO KLC2 ANKZF1 BAHD1 FGD1 PICK1	9.81e-05	197	165	8	3800_DN
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	SPN HAP1 CCDC85C ITPR1 FGD1 KIF13A MAPK8IP2 TJP3	9.81e-05	197	165	8	2282_DN
Drug	deferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A	TRIM2 WIPF1 VPS13C GATC IER5 GGCX ZKSCAN1 TJP2	9.81e-05	197	165	8	460_DN
Drug	Etodolac [41340-25-4]; Up 200; 14uM; PC3; HT_HG-U133A	WIPF1 DSCAM PSG1 ARHGEF17 ITPR1 LIMK1 PAK3 ALPP	9.81e-05	197	165	8	2091_UP
Drug	Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A	TRIO ARHGEF17 SLC30A3 NPM3 ITPR1 CCNT1 PCDH7 PICK1	9.81e-05	197	165	8	3293_UP
Drug	Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; PC3; HT_HG-U133A	DSCAM TRIO HAP1 WRNIP1 NPM3 ITPR2 NEURL1 TJP3	9.81e-05	197	165	8	5753_UP
Drug	Fipexide hydrochloride [34161-23-4]; Up 200; 9.4uM; HL60; HG-U133A	SPN HAP1 TRAIP TRPS1 MCL1 KAT6B PICK1 BEGAIN	9.81e-05	197	165	8	1560_UP
Drug	thioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	TRIM2 PSG1 SPN MCL1 EXTL3 BAHD1 KIF13A FOXP3	9.81e-05	197	165	8	5916_UP
Drug	Idoxuridine [54-42-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	IPPK SPN TRAIP ARFGEF1 CCDC85C LARP4B ALMS1 LMBR1L	1.02e-04	198	165	8	4785_DN
Drug	NS-398; Up 200; 10uM; PC3; HT_HG-U133A	CRYBG2 TRIO PSG1 HAP1 ITPR1 ITPR2 PICK1 TJP3	1.02e-04	198	165	8	6892_UP
Drug	Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	DSCAM SPN HAP1 SLC30A3 ITPR1 SLC22A18AS LPL PCDH7	1.02e-04	198	165	8	5663_UP
Drug	Perhexiline maleate [6724-53-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	DSCAM PNN CCDC85C EXTL3 BAHD1 LARP4B ZKSCAN1 GPRC5B	1.02e-04	198	165	8	5501_DN
Drug	Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT_HG-U133A	VPS13C PHLDA3 EXTL3 FTCD PRX GGCX SLC22A18AS BEGAIN	1.02e-04	198	165	8	2715_UP
Drug	Azacyclonol [115-46-8]; Up 200; 15uM; HL60; HG-U133A	CUL4A CRYBG2 EXTL3 PRX SLC22A18AS MAP1S CEP170B FOXP3	1.02e-04	198	165	8	2020_UP
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; PC3; HT_HG-U133A	CHRNA6 CRYBG2 TRIM2 PHLDA3 MCL1 ZKSCAN1 PAK3 MAPK8IP2	1.05e-04	199	165	8	6349_UP
Drug	Progesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A	CRYBG2 TRIM2 PSG1 EXTL3 SLC30A3 LIMK1 KIF13A MAPK8IP2	1.05e-04	199	165	8	3287_UP
Drug	benserazide hydrochloride; Down 200; 10uM; MCF7; HG-U133A	ADGRG3 WIPF1 SPN KALRN ANKZF1 ITPR2 PTPRS NEURL1	1.05e-04	199	165	8	641_DN
Disease	Hypoxic Brain Damage	ITPR1 ITPR2	2.96e-05	2	161	2	C1140716
Disease	Anoxic Encephalopathy	ITPR1 ITPR2	2.96e-05	2	161	2	C0003132
Disease	Brain Hypoxia	ITPR1 ITPR2	2.96e-05	2	161	2	C1527348
Disease	Anoxia of brain	ITPR1 ITPR2	2.96e-05	2	161	2	C0995195
Disease	African Burkitt's lymphoma	TCF3 FTCD RET	6.91e-05	15	161	3	C0343640
Disease	Burkitt Leukemia	TCF3 FTCD RET	6.91e-05	15	161	3	C4721444
Disease	Neurodevelopmental Disorders	DSCAM TRIO ITPR1 KMT2C KMT5B	1.60e-04	93	161	5	C1535926
Disease	complex cortical dysplasia with other brain malformations (is_implicated_in)	KIF26A APC2	1.76e-04	4	161	2	DOID:0090131 (is_implicated_in)
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	RET FH EPAS1	2.61e-04	23	161	3	C1708353
Disease	factor XI measurement, coronary artery disease	JCAD MAP1S ANLN LPL SMG6	4.30e-04	115	161	5	EFO_0001645, EFO_0004694
Disease	Mental Retardation, X-Linked	OPHN1 FGD1 PAK3	5.25e-04	29	161	3	C1136249
Disease	Urogenital Abnormalities	APC2 FGD1	6.10e-04	7	161	2	C0042063
Disease	PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME	POLA1 PAK3	8.11e-04	8	161	2	C0796250
Disease	Burkitt Lymphoma	TCF3 FTCD RET	9.97e-04	36	161	3	C0006413
Disease	squamous cell carcinoma, esophageal carcinoma	HAP1 SMG6	1.29e-03	10	161	2	EFO_0000707, EFO_0002916
Disease	autism spectrum disorder (implicated_via_orthology)	DSCAM NLGN4Y NLGN4X KMT5B SH3RF2	1.51e-03	152	161	5	DOID:0060041 (implicated_via_orthology)
Disease	Colorectal Carcinoma	TCF3 KALRN APC2 ARFGEF1 CORO1B RET CSMD3 KMT2C NLGN4X PTPRS NEURL1	1.70e-03	702	161	11	C0009402
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ITPR2	1.88e-03	12	161	2	DOID:1441 (implicated_via_orthology)
Disease	Carcinoma, Neuroendocrine	RET FH	1.88e-03	12	161	2	C0206695
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	IFT88 PKD1	2.58e-03	14	161	2	DOID:898 (implicated_via_orthology)
Disease	actinic keratosis	TRPS1 HERC2	2.58e-03	14	161	2	EFO_0002496
Disease	N-acetylmethionine measurement	ITPR1 ALMS1	2.97e-03	15	161	2	EFO_0021427
Disease	myocardial infarction	JCAD PSG1 KALRN OAS3 ZNF831 LPL SMG6	3.20e-03	350	161	7	EFO_0000612
Disease	coronary artery disease, factor VII measurement	JCAD MAP1S LPL SMG6	3.25e-03	111	161	4	EFO_0001645, EFO_0004619
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	IFT88 PKD1	3.38e-03	16	161	2	DOID:0110861 (implicated_via_orthology)
Disease	Antithrombotic agent use measurement	PSG1 LPL NEURL1	3.40e-03	55	161	3	EFO_0009925
Disease	clonal hematopoiesis mutation measurement	SETD1A ITPR1 HERC2	3.40e-03	55	161	3	EFO_0020949
Disease	factor VIII measurement, coronary artery disease	JCAD MAP1S LPL SMG6	3.47e-03	113	161	4	EFO_0001645, EFO_0004630
Disease	level of Sphingomyelin (d32:1) in blood serum	NUP88 ERMP1	3.81e-03	17	161	2	OBA_2045173
Disease	body weight	IPPK MAN1A1 VPS13C TRPS1 NUP88 RET ITPR1 MICALL2 ANLN PKD1 SCRIB KAT6B PCDH7 EPAS1 GPRC5B	3.90e-03	1261	161	15	EFO_0004338
Disease	von Willebrand factor measurement, coronary artery disease	JCAD MAP1S LPL SMG6	4.05e-03	118	161	4	EFO_0001645, EFO_0004629
Disease	cD177 antigen measurement	PSG1 PSG7	4.27e-03	18	161	2	EFO_0021866
Disease	colorectal cancer (is_implicated_in)	TCF3 AMER1 MCL1 FOXP3	4.42e-03	121	161	4	DOID:9256 (is_implicated_in)
Disease	SARS-CoV-2 antibody measurement, response to COVID-19 vaccine	DSCAM APC2 SORCS3	4.76e-03	62	161	3	EFO_0803360, EFO_0803362
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	JCAD LPL SMG6	4.98e-03	63	161	3	EFO_0001645, EFO_0004792

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGAGTPLSGTFRVEK	CCDC185	151	Q8N715
GPRLLFGSGSKGSRS	SMG6	431	Q86US8
TRSAKGFGARGPDVL	EPAS1	681	Q99814
GRFKGESSGRILSPG	CSMD3	1416	Q7Z407
FGTPSNLGKGRRAAA	CLPX	441	O76031
QAFPRTGGSGLSRKD	BEGAIN	566	Q9BUH8
GTGVKPRYISGTVRG	ARFGEF1	1061	Q9Y6D6
GRTTDLSKGLQSPRG	ALMS1	2551	Q8TCU4
GGGAFLVLPLSKTGR	CORO1B	56	Q9BR76
TLFKGPRLGLGDGSG	ADGRG3	161	Q86Y34
ICTLPSFFGGGRSKG	AMER1	66	Q5JTC6
SGALRSGPSLRKDGD	SMDT1	16	Q9H4I9
RLTGGRKGFGSSGLR	SLC22A18AS	71	Q8N1D0
TRKRGPSEETGGAVF	CCNT1	571	O60563
RSLASSAQPGLGKGR	CEP170B	1526	Q9Y4F5
GTGTFSPRPRAVKSG	C1orf147	196	Q96MC9
DGCSGGGRTRKRSPG	ERMP1	41	Q7Z2K6
LAGTGSRGGTRELLP	ASXL2	731	Q76L83
LLRGRPGKTVDLGSG	ANTKMT	71	Q9BQD7
PGATVTLTGGFRRGK	POLM	311	Q9NP87
SGSDKGRAGTLSPGL	IPPK	271	Q9H8X2
ASRKTGSSQGRLPGD	OPHN1	786	O60890
SARSGPRFKEALGGP	ITPR2	1581	Q14571
FTGRGSPGRGQKTKV	KAT6B	366	Q8WYB5
KLFGGPGSRRPSADS	ARHGEF17	131	Q96PE2
RVRKPGGSSGDRGSN	ARHGEF17	486	Q96PE2
ARLRSIFPGGGDKTN	PAK3	46	O75914
SALGGGKLPGGARRS	DPY19L2P1	36	Q6NXN4
LSGRGGRGRSKLKSG	KMT2C	901	Q8NEZ4
TKGLAGGDRASRPLS	MAP1S	886	Q66K74
RAPLGGRQGFTSKAD	GATC	11	O43716
KASDLLGARGPGGTF	FOXP3	31	Q9BZS1
TFRLKSGSGPVRITG	NPM3	121	O75607
LRSGGGVGDVLRKPS	ITPR1	2551	Q14643
KGSGFPDGEGSSRRP	SPN	326	P16150
SSRPAGKGVEGLARV	HERC2	181	O95714
LNKTSGGGGRSGVRL	GABBR1	481	Q9UBS5
SGGGLVQPRGSLRLS	IGHV3-38	26	A0A0C4DH36
GGTGIKPFLERFGER	ANLN	366	Q9NQW6
SGGGLVQPGRSLRLS	IGHV3-9	26	P01782
RRGTGAFKSRVGLPA	KMT5B	326	Q4FZB7
KFDSGGERGAGLPLS	JCAD	1021	Q9P266
LRGVKLSLSGGGPEF	MAPK8IP2	731	Q13387
GKAGRAGTPSEGSFL	KIAA1614	121	Q5VZ46
ESSPGLGRGRKNSFG	LARP4B	486	Q92615
AGSGEFRTLRKGFSP	CCDC85C	291	A6NKD9
GLRGPTGQKVVRFGD	C1orf198	96	Q9H425
PGAGGTQRLTRAVGK	ECHS1	171	P30084
ESSGVGRVGAGSRPK	MICALL2	541	Q8IY33
RAGEAPRKVSGSFAG	MICALL2	616	Q8IY33
LRRGFSDSGGGPPAK	PNN	61	Q9H307
TFTRGSPGRSIGIQK	LPL	211	P06858
GSKGDGIPDRFSVLG	IGLV9-49	76	A0A0B4J1Y8
GSKRRLDASEGGGGT	PCDH7	221	O60245
KSPAGRLGFSVRGGS	PDZD7	91	Q9H5P4
GRFSGLLGRGAAPTL	IL16	881	Q14005
VSGGRDKRGGPILTF	KALRN	46	O60229
RASGPGEGLVRGKLS	KIF24	686	Q5T7B8
GKGFRDRNVTGTPLT	ADAMTSL2	421	Q86TH1
RGLVAGGSRALGPSV	KIF26A	1501	Q9ULI4
TGFLGPTGRGTDELL	GCAT	236	O75600
GRGDGAREGFLLSKA	TWNK	131	Q96RR1
RKGELTVFTGPTGSG	TWNK	406	Q96RR1
TGEPSKRSRGALGSI	MGST3	106	O14880
RSPTRGSEFSGKGDV	PTPRZ1	481	P23471
SGGGLVQPGRSLRLS	IGHV3-49	26	A0A0A0MS15
LAVSGGTLPRRKGSG	TAMALIN	71	Q7Z6J2
PKLGGRSGFGERNAT	POLA1	671	P09884
GSGSLRRSGSFGKLR	KLC2	536	Q9H0B6
LRKSRGGQFLTPLGS	PTPRS	1161	Q13332
RTAGFPNGSLGKRPS	GPRC5B	346	Q9NZH0
RGGSSGAKFRISLGL	RPL23	6	P62829
LRGSSIFGLAPGKAR	ALPP	391	P05187
AGGSRKGTPTARCLG	PANO1	31	I0J062
FGGDPKRVTIFGSGA	NLGN4Y	241	Q8NFZ3
KGRSVGAALGRSSLP	C6orf132	851	Q5T0Z8
KRRPGSGTDGLRLQG	FAM157B	206	P0CG42
KTRGTGSDAVPRGLA	CHRNA6	361	Q15825
GSKPGRTRGDGALQS	APC2	1481	O95996
KSSAARPVSRGGVGL	IFT74	6	Q96LB3
RIKSGRDGSGGSRGK	IFT88	726	Q13099
SGGFKEGRAGFRPVE	CASC3	316	O15234
SGRSLFFGGKGAPLQ	ANKZF1	301	Q9H8Y5
TGKTFPRASGLGARE	FRMPD4	1111	Q14CM0
DIRFLGSGPRSGLGE	FH	341	P07954
EAKFLGSGTGFRPIG	EXTL3	626	O43909
PRKGSFSALVGRTNG	CUL4A	6	Q13619
PEGEGLRSFSGIKGL	CMYA5	3846	Q8N3K9
GPFGSRATGRGTGKA	HAP1	111	P54257
GGSRPTSRLGGSLLF	CRYBG2	896	Q8N1P7
SSKKRPRLGDLGGGS	BAHD1	166	Q8TBE0
AALSPRGRGSKGLGT	MAPKAPK5-AS1	26	Q8N8E1
GGRKGSGPAALRLTE	MAN1A1	26	P33908
GRLVKSGSLGSARGA	DENND4B	956	O75064
TGGSPGERKRTRLGG	DDHD1	136	Q8NEL9
ESFVETLKRGGGPRS	EIF2B2	16	P49770
SGGGFLLSGPTARAL	B3GNT6	281	Q6ZMB0
KYVRGRPGTGRGVAS	FAM110C	46	Q1W6H9
SACSRRLKGSGGGVP	PEX11B	151	O96011
RGTKFGLFTPGSRIE	CPOX	401	P36551
FGGDPKRVTIFGSGA	NLGN4X	241	Q8N0W4
PERGLGSKSLRAFVG	FTCD	331	O95954
KGDDGTRGVTGRFTF	PSG1	126	P11464
GGATRPGGRLLATEK	MCL1	26	Q07820
DRGPALAGSGKGFSL	PKD1	1671	P98161
VSKGGSFGRGTDLRD	OAS3	456	Q9Y6K5
SSFLVVRLRGPSGGG	NUP88	76	Q99567
GELSSRRSLPNKTGG	KIF13A	1756	Q9H1H9
LNRGGPGTSRDLSLG	DSCAM	1911	O60469
RAGKPFGSGRAGSTG	HIC2	141	Q96JB3
SFSGLLRKSPGGGRE	IER5	276	Q5VY09
EGGGGSFPRIKATGR	RGL2	756	O15211
QARGLRAKGPGGTSD	RAB11FIP1	26	Q6WKZ4
GRVTFPGGLKGSARF	TGFBR3L	21	H3BV60
SLGGSRKATDRGVAP	TOGARAM2	991	Q6ZUX3
ESEGFAGSRKGVLGR	LMBR1L	136	Q6UX01
ADGSRGSRPLAKGSR	SORCS3	151	Q9UPU3
GGSGGSRKSRSLEKR	TMEM184A	391	Q6ZMB5
KTSGLRGRGGAGFPT	NDUFV1	81	P49821
GASEPGLLARRGSGS	FGD1	36	P98174
EFLVGSSPGGSGRAL	SPINDOC	76	Q9BUA3
LSLGAGGRATPGVFR	TMEM151A	406	Q8N4L1
ARSERGLGFSIAGGK	SCRIB	866	Q14160
KRGDGTGGVTGRFTF	PSG7	126	Q13046
GSGLRGALRLPSFKV	SETD1A	881	O15047
PSSRLGRNKGFSRGP	ARHGAP4	911	P98171
RGGKASDVALPRGSS	TGIF2	96	Q9GZN2
RGLQLFEAKGTGGRP	PHLDA3	36	Q9Y5J5
GSRPTQKGDLRGAAG	ZNF837	41	Q96EG3
TSGGTFIGIGRKTPD	TRPS1	311	Q9UHF7
TKDFVGPSERGGGRA	THRAP3	816	Q9Y2W1
KRGFGIAVSGGRDNP	TJP2	41	Q9UDY2
SGPRQDSRIGKLLGF	GGCX	26	P38435
KVTRSGGARPGALSF	NEURL1	341	O76050
PGAGGLYKRGSVRSL	SRCIN1	421	Q9C0H9
STFLGPGLGGKSGER	TCF3	91	P15923
LTRAASLRGGVGAPG	PPM1H	206	Q9ULR3
TAFGGGERVSLLSPG	SPANXA2-OT1	96	Q8N9U9
KLPTLGARARVGGEG	PRX	1246	Q9BXM0
NIRGTGSDGPRKRGL	PSTK	6	Q8IV42
AALSGRPLGTRLGFG	NDUFB5	16	O43674
SLPGLKSRGSRAAGG	TBC1D10B	661	Q4KMP7
RGTALGGGSIRQSPL	WIPF1	226	O43516
RDFGDSLARGGKGFL	VPS13C	3511	Q709C8
AGAGRSAVGKDLTRP	TACC2	1431	O95359
GGKQGPRGSRSSRAD	ZBTB47	356	Q9UFB7
RFLQGRGPSEKGSSR	SKOR2	786	Q2VWA4
LRESRKVGPGYLGSG	RET	816	P07949
RGGAGGSLRLKSLFT	SLC30A3	21	Q99726
FPVARSSSPGRKGSG	WRNIP1	126	Q96S55
KDPRRGFGIAISGGR	TJP3	16	O95049
GFPGVFEGAGSRKRK	ZNF366	66	Q8N895
VTGKFRGGVNPFTRG	ZDHHC8	221	Q9ULC8
PGTLGQGSLRKGRSS	SH3RF2	501	Q8TEC5
GPREKGKGLGRSFSL	ZKSCAN1	346	P17029
PTSAGGGSQRLFRKI	PPIP5K2	201	O43314
PSLGSDGRKRQVSGL	ZNF831	1606	Q5JPB2
DGQFKSRFGIRGRSP	TRIM2	516	Q9C040
RQGSLTKGLAPRSGD	WNT9B	266	O14905
RRPVGASFSFGGKLV	SEC31A	391	O94979
SGRAGVGPKDSRLSR	SHE	91	Q5VZ18
APAGRRTFLTDLGGG	TREML1	71	Q86YW5
SRDTRGAAGPLDKGG	PICK1	396	Q9NRD5
KGQPESGILRTGTFR	USP8	606	P40818
LSGGRDKRGGPILTF	TRIO	76	O75962
KGGPGSTLSFVGKRR	TRIR	106	Q9BQ61
STRDRFQLTGDPGKG	SIGLEC16	86	A6NMB1
GSRDRKSGGRLGSPK	ZC3H18	856	Q86VM9
GFDGLGGRTKFIQPT	TRAIP	416	Q9BWF2
DKPGLRRAAQGGGST	TMEM108	276	Q6UXF1
ALAGASSGRELGRPK	ZNF263	356	O14978
GSLGSPASQRKDLGR	LIMK1	306	P53667
RGLPGSGKSFLARTL	N4BP2	446	Q86UW6
LATGKRPGGSTFTIG	GRIN2D	616	O15399
GGASKPRTARGGGLS	NECAP1	171	Q8NC96