Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsmall-subunit processome

UTP20 KRR1 BMS1

1.93e-0476313GO:0032040
GeneOntologyCellularComponentpreribosome

UTP20 KRR1 BMS1

6.35e-04114313GO:0030684
GeneOntologyCellularComponent90S preribosome

UTP20 BMS1

8.43e-0429312GO:0030686
DomainHMG_box

BBX TFAM HMGXB4

8.30e-0553303PF00505
DomainHMG_BOX_2

BBX TFAM HMGXB4

8.78e-0554303PS50118
DomainHMG

BBX TFAM HMGXB4

8.78e-0554303SM00398
Domain-

BBX TFAM HMGXB4

9.27e-05553031.10.30.10
DomainHMG_box_dom

BBX TFAM HMGXB4

1.53e-0465303IPR009071
DomainRhoGAP

ARHGAP5 ARHGAP18

4.44e-0362302SM00324
DomainRhoGAP

ARHGAP5 ARHGAP18

4.58e-0363302PF00620
DomainRHOGAP

ARHGAP5 ARHGAP18

4.73e-0364302PS50238
DomainRhoGAP_dom

ARHGAP5 ARHGAP18

4.73e-0364302IPR000198
Domain-

ARHGAP5 ARHGAP18

4.73e-03643021.10.555.10
Domain-

RABL6 ARHGAP5 ABCF1 DDX24 BMS1

6.23e-037463053.40.50.300
DomainRho_GTPase_activation_prot

ARHGAP5 ARHGAP18

8.76e-0388302IPR008936
DomainP-loop_NTPase

RABL6 ARHGAP5 ABCF1 DDX24 BMS1

1.06e-02848305IPR027417
PathwayREACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL

UTP20 KRR1 BMS1

5.72e-0560183M27613
PathwayBIOCARTA_D4GDI_PATHWAY

ARHGAP5 PRF1

1.01e-0412182M15513
PathwayBIOCARTA_D4GDI_PATHWAY

ARHGAP5 PRF1

1.19e-0413182MM1380
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

UTP20 ABCF1 KRR1 SPOUT1 DDX24 TFAM BMS1

2.06e-0834931725665578
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

ZBTB10 ARHGAP5 UTP20 KRR1 SPOUT1 DDX24 TFAM BMS1

5.75e-0784731835850772
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ZBTB10 ARHGAP5 BOD1L1 ANKRD12 AHI1 KRR1 SPOUT1 FEZ2

3.62e-06108431811544199
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

UTP20 ABCF1 KRR1 SPOUT1 DDX24 BMS1

3.81e-0648331636912080
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

UTP20 ABCF1 KRR1 SPOUT1 DDX24 TFAM BMS1

3.82e-0675931735915203
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

UTP20 ABCF1 KRR1 SPOUT1 DDX24 TFAM BMS1

5.71e-0680731722681889
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

ZBTB10 KRR1 DDX24 TFAM BMS1

1.04e-0533031533301849
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

BOD1L1 KRR1 SPOUT1 DDX24 TFAM

1.08e-0533331536779763
Pubmed

Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.

ABCF1 BBX HMGXB4

1.72e-055631326919559
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ZBTB10 UTP20 ABCF1 KRR1 SPOUT1 DDX24 TFAM BMS1

1.82e-05135331829467282
Pubmed

The small-subunit processome is a ribosome assembly intermediate.

UTP20 KRR1

2.15e-05831215590835
Pubmed

Nucleolar maturation of the human small subunit processome.

UTP20 KRR1 BMS1

2.34e-056231334516797
Pubmed

Nucleolar proteome dynamics.

UTP20 STXBP1 KRR1 DDX24 BMS1

3.25e-0541931515635413
Pubmed

Directed proteomic analysis of the human nucleolus.

UTP20 KRR1 SPOUT1 BMS1

3.45e-0520831411790298
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

ABCF1 BBX KRR1 DDX24 TFAM BMS1

3.46e-0571331629802200
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

UTP20 ZNF800 ABCF1 BBX KRR1 TFAM HMGXB4 BMS1

3.76e-05149731831527615
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ARHGAP5 UTP20 BOD1L1 FAM227B SPOUT1 BMS1

4.13e-0573631629676528
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ZBTB10 UTP20 BBX DDX24 HMGXB4 BMS1

9.56e-0585731625609649
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

UTP20 ABCF1 KRR1 SPOUT1 DDX24 TFAM BMS1

9.72e-05125731736526897
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

ZNF800 ABCF1 BBX TFAM HMGXB4

1.01e-0453331530554943
Pubmed

Identification of novel ARF binding proteins by two-hybrid screening.

RABL6 ANKRD12

1.60e-042131216582619
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

BOD1L1 BBX KRR1 DDX24 TFAM HMGXB4

1.72e-0495431636373674
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZBTB10 BOD1L1 BBX DDX24 HMGXB4

1.87e-0460831536089195
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

UTP20 BOD1L1 KRR1 SPOUT1 DDX24 BMS1

2.09e-0498931636424410
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

UTP20 KRR1 DDX24 BMS1

2.09e-0433231425693804
Pubmed

Human transcription factor protein interaction networks.

ZBTB10 BBX KRR1 DDX24 TFAM HMGXB4 BMS1

2.15e-04142931735140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CYLC1 BOD1L1 BBX STXBP1 UNCX TRDN TFAM

2.27e-04144231735575683
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

UTP20 KRR1 SPOUT1 BMS1

2.29e-0434031429478914
Pubmed

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

RABL6 KRR1 DDX24

2.32e-0413431328695742
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

UTP20 ABCF1 KRR1 DDX24 BMS1

2.61e-0465331522586326
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

UTP20 ZNF800 ABCF1 BBX DDX24

2.64e-0465531535819319
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ABCF1 BBX DDX24 TFAM HMGXB4 BMS1

3.38e-04108231638697112
Pubmed

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.

ABCF1 SPOUT1 TFAM BMS1

4.36e-0440331435253629
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

UTP20 BBX STXBP1 DDX24

4.65e-0441031426949251
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

UTP20 ABCF1 GTF3A SPOUT1

6.82e-0445431433226137
Pubmed

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

UTP20 KRR1 DDX24

8.85e-0421231333462405
InteractionZNF2 interactions

ZNF800 SPOUT1 DDX24 BMS1

6.68e-0680314int:ZNF2
InteractionMNDA interactions

UTP20 KRR1 SPOUT1 DDX24 BMS1

9.35e-06188315int:MNDA
InteractionMAGEB2 interactions

ZNF800 BBX KRR1 SPOUT1 DDX24 BMS1

1.32e-05349316int:MAGEB2
InteractionMEN1 interactions

ZBTB10 ARHGAP5 UTP20 BOD1L1 KRR1 SPOUT1 DDX24 TFAM BMS1

1.66e-051029319int:MEN1
InteractionCENPA interactions

ZBTB10 UTP20 BBX DDX24 HMGXB4 BMS1

2.04e-05377316int:CENPA
InteractionH2AB2 interactions

BBX KRR1 DDX24 BMS1

2.12e-05107314int:H2AB2
InteractionZNF330 interactions

ZBTB10 UTP20 BBX DDX24 HMGXB4 BMS1

5.23e-05446316int:ZNF330
InteractionH2AB3 interactions

ZNF800 KRR1 DDX24 BMS1

5.42e-05136314int:H2AB3
InteractionZBTB2 interactions

ZBTB10 ARHGAP18 KRR1 DDX24 TFAM BMS1

5.49e-05450316int:ZBTB2
InteractionANOS1 interactions

ZNF800 BBX DDX24 BMS1

6.59e-05143314int:ANOS1
InteractionSNRNP70 interactions

RABL6 ABCF1 BBX KRR1 SPOUT1 DDX24 TFAM BMS1

9.07e-05984318int:SNRNP70
InteractionH1-1 interactions

ARHGAP5 KRR1 SPOUT1 DDX24 EGFL6 BMS1

1.06e-04507316int:H1-1
InteractionH2BC5 interactions

CYLC1 ABCF1 KRR1 TRDN TFAM

1.39e-04331315int:H2BC5
InteractionPOLR1E interactions

ZBTB10 UTP20 BBX KRR1 BMS1

1.80e-04350315int:POLR1E
InteractionKRR1 interactions

ZNF800 KRR1 DDX24 TFAM BMS1

2.60e-04379315int:KRR1
InteractionUSP36 interactions

UTP20 ABCF1 KRR1 SPOUT1 DDX24 BMS1

2.63e-04599316int:USP36
InteractionGRM2 interactions

BOD1L1 KRR1 SPOUT1 DDX24 TFAM

2.67e-04381315int:GRM2
InteractionBET1 interactions

RABL6 KRR1 DDX24 TRDN TFAM

2.80e-04385315int:BET1
InteractionNUP43 interactions

ZBTB10 UTP20 BOD1L1 BBX DDX24 BMS1

3.30e-04625316int:NUP43
InteractionPRKRA interactions

ZNF800 STXBP1 KRR1 DDX24 BMS1

3.34e-04400315int:PRKRA
InteractionRTRAF interactions

ZBTB10 ABCF1 SPOUT1 FEZ2

3.57e-04222314int:RTRAF
InteractionKLF9 interactions

BBX DDX24 BMS1

3.89e-0493313int:KLF9
InteractionZCCHC10 interactions

BBX DDX24 PRR13 HMGXB4

4.50e-04236314int:ZCCHC10
InteractionNIFK interactions

UTP20 BBX KRR1 DDX24 BMS1

4.69e-04431315int:NIFK
CytobandEnsembl 112 genes in cytogenetic band chr9q34

RABL6 STXBP1 SPOUT1

1.36e-03325313chr9q34
CytobandEnsembl 112 genes in cytogenetic band chr6q23

AHI1 SGK1

2.95e-03119312chr6q23
CytobandEnsembl 112 genes in cytogenetic band chr6q22

ARHGAP18 TRDN

3.35e-03127312chr6q22
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP5 ARHGAP18

9.93e-0450172721
CoexpressionGSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_UP

STXBP1 ARHGAP18 SGK1 PRF1 HMGXB4

1.85e-06175315M8578
CoexpressionGSE35435_RESTING_VS_IL4_TREATED_MACROPHAGE_UP

ABCF1 STXBP1 CSRNP2 TRDN PRF1

3.56e-06200315M9542
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE

ZBTB10 BBX GTF3A KRR1 DDX24 TFAM

1.70e-05474316M40991
CoexpressionNAKAYA_PBMC_FLUMIST_AGE_18_50YO_7DY_DN

ZBTB10 ARHGAP5 ELL2 BBX KRR1 TFAM HMGXB4

4.68e-05844317M41129
CoexpressionGSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_DN

SCO1 AHI1 FEZ2 HMGXB4

5.02e-05173314M6923
CoexpressionGSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN

ARHGAP5 ELL2 ARHGAP18 PRF1

5.85e-05180314M6317
CoexpressionGSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP

UTP20 STXBP1 CSRNP2 FEZ2

8.47e-05198314M8404
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP

ARHGAP5 SGK1 PRF1 PRR13

8.64e-05199314M9214
CoexpressionGSE40655_FOXO1_KO_VS_WT_NTREG_UP

ARHGAP5 BOD1L1 BBX SGK1

8.81e-05200314M9439
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP

ABCF1 ELL2 DDX24 PRF1

8.81e-05200314M8505
CoexpressionGSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_UP

AHI1 GTF3A SPOUT1 BMS1

8.81e-05200314M7077
CoexpressionGSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_UP

ARHGAP5 AHI1 ARHGAP18 SPOUT1

8.81e-05200314M9293
CoexpressionGSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN

SCO1 ELL2 STXBP1 PRR13

8.81e-05200314M4343
CoexpressionSENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP

ZBTB10 BOD1L1 ELL2 ARHGAP18 TFAM

1.04e-04404315M19488
CoexpressionNAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN

BOD1L1 ELL2 BBX DDX24 TFAM HMGXB4

1.26e-04680316M41089
CoexpressionGARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP

ARHGAP5 ANKRD12 SGK1

1.29e-0483313M15537
CoexpressionNELSON_RESPONSE_TO_ANDROGEN_UP

ZBTB10 ELL2 SGK1

1.29e-0483313M13903
CoexpressionHALLMARK_ANDROGEN_RESPONSE

ZBTB10 ELL2 SGK1

2.31e-04101313M5908
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BOD1L1 ELL2 SGK1

2.17e-041693130867528101767fc65e93b3561480bf830c50368d
ToppCellCOVID-19_Mild-Neu_2|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

ARHGAP5 KRR1 CSRNP2

2.28e-04172313f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP18 SGK1 EGFL6

2.56e-04179313c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GTF3A DDX24 PRF1

2.69e-04182313f30e5a21b49f30b82e2b6f1fd2daefd805a40083
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP18 SGK1 EGFL6

2.69e-041823137dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCellCOVID-19_Severe-Lymphoid_T/NK-MAIT|COVID-19_Severe / Disease group, lineage and cell class

GTF3A DDX24 PRF1

2.69e-0418231319045db5c726c06ec6e4feb4311633c8164ddb3c
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GTF3A DDX24 PRF1

2.69e-041823131444cdc4522a70a40d697ccadf54cf26d327ade0
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GTF3A DDX24 PRF1

2.69e-04182313cccac9f85825f4e310b86e37ee6320769a670501
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GTF3A DDX24 PRF1

2.69e-0418231349eced222e8f90c2b59bcc7d56b62c3e703fcce5
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 ARHGAP18 SGK1

2.74e-04183313ff751a97466807bf04b5a0740138c61e298cd1fc
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 ARHGAP18 SGK1

2.87e-04186313c7e2134454ab5d0885050dd1bb3c3bd15bf497ac
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 ANKRD12 DDX24

2.92e-04187313663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

BOD1L1 ELL2 ARHGAP18

3.01e-04189313a48df46274d51e84ffb40264646de7346104efb9
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB10 UTP20 TFAM

3.05e-0419031336e83995021ba16690f84e2077a9e8baec547d05
ToppCellSevere-Lymphoid-NK-Treg|Severe / Condition, Lineage, Cell class and cell subclass

UTP20 STXBP1 PRF1

3.05e-04190313e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BBX GTF3A PRF1

3.05e-04190313373629dde5eda722424c5e6087763f0c5db67cf4
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB10 UTP20 TFAM

3.05e-04190313d26be9e1b676f750e716b91ebc3598fac3735612
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 ARHGAP18 SGK1

3.05e-041903130a944da2aaaef9289b2a4ffe360b0338724fd59b
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BBX GTF3A PRF1

3.10e-041913136e1d00404d795ec7cf60f685e42e4ad9a16ac596
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BBX GTF3A PRF1

3.10e-04191313f158e393976b685b896a41871bda1ab65a8b58f5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHI1 ELL2 DDX24

3.10e-041913131ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell390C-Myeloid-Mast_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

ELL2 ARHGAP18 SGK1

3.10e-0419131388bcd0b85b2112cef15c9e44d1429f9fba4a3400
ToppCell390C-Myeloid-Mast_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

ELL2 ARHGAP18 SGK1

3.10e-04191313c1517ea7b10a7f732725b4c0224fbfecae80d18b
ToppCellASK452-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

AHI1 ELL2 ARHGAP18

3.15e-041923138269b88ff6073a908f547fcc7c5941f2e8289694
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZBTB10 DDX24 SGK1

3.15e-04192313348d39da3016dc6dbfa65d108e5def35aa7f19dd
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

KRR1 DDX24 PRR13

3.25e-041943136cf9d59aec8dd18fa2fc1652ddd0f5ef1f24bcb6
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 ANKRD12 SGK1

3.25e-04194313e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

ANKRD12 STXBP1 DDX24

3.25e-041943138aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 ARHGAP18 SGK1

3.25e-04194313449ce4167d64c170d914e0250f739eabedcf915d
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ELL2 ARHGAP18 SGK1

3.30e-041953139d649ac7d2af313481069c95349efc0c68449e2b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD12 AHI1 DDX24

3.30e-04195313ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 AHI1 TRDN

3.30e-041953135c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell390C-Myeloid|390C / Donor, Lineage, Cell class and subclass (all cells)

ELL2 ARHGAP18 SGK1

3.34e-041963135b690062db162e9ddd1a32b1be4d10f5f99c9407
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ARHGAP5 ARHGAP18 SGK1

3.40e-0419731366339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD12 KRR1 DDX24

3.40e-04197313ef2d1f56acd0be43e69bba7f73f6909ba87f1cb3
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

BOD1L1 ANKRD12 DDX24

3.40e-041973135c33454b10023decd2f5ccda9229b6512659711e
ToppCellnucseq-Immune-Immune_Myeloid-IM|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ELL2 ARHGAP18 SGK1

3.40e-041973136f41c8f815851968849428ec92c16745bd01a3fb
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

BOD1L1 ANKRD12 AHI1

3.40e-041973130fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellnucseq-Immune-Immune_Myeloid-IM-IM|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ELL2 ARHGAP18 SGK1

3.40e-04197313304044ace926943b8eb588f686ecbe5d1689a809
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 ARHGAP18 SGK1

3.40e-04197313f807d8cd377ee58c02be7f71b39cd227f6b4f5df
ToppCellBL-critical-LOC-Lymphoid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GTF3A DDX24 PRF1

3.45e-041983131c0227e58a64c0bf509bfb9578fb91277316b120
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

ZNF800 BOD1L1 ANKRD12

3.45e-0419831376d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellmoderate-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANKRD12 DDX24 PRF1

3.45e-041983130a868098b1ee4b28b2149ed766acb09e9c0ce14c
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

BOD1L1 ANKRD12 DDX24

3.45e-0419831344417089b62056269cac38d3134ff209c05b7007
ToppCell(1)_T_cell-(11)_Activated_CD4_T|(1)_T_cell / shred on Cell_type and subtype

ARHGAP5 ANKRD12 KRR1

3.45e-041983134b9ad91342f622c63e476d4f6a0ae5bf282a7ef5
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BOD1L1 ANKRD12 DDX24

3.45e-0419831328ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AHI1 STXBP1 DDX24

3.45e-041983138ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellmild-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARHGAP5 ANKRD12 DDX24

3.50e-041993133e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 ARHGAP18 SGK1

3.50e-04199313e225c1bfc55947c30e7948be851daea04975efa5
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

BOD1L1 ANKRD12 ARHGAP18

3.50e-0419931361b1ed2db71b96157b92b7535d1955a4033098da
ToppCellHealthy/Control|World / Disease group and Cell class

ANKRD12 KRR1 DDX24

3.50e-041993132623c42b3e79e401a485879b52e8bbcbc581544d
ToppCellT_cells-CCR7+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ZBTB10 ARHGAP5 ELL2

3.50e-04199313467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

BOD1L1 ANKRD12 BBX

3.50e-04199313c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell5'-Adult|5' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ELL2 SGK1 PRR13

3.50e-041993138b7b1fcea9a06522fdfab85d0dfd33010ae96d75
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

BOD1L1 ANKRD12 BBX

3.50e-0419931318a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ANKRD12 STXBP1 DDX24

3.50e-04199313f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellmild-CD4+_Tcm|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARHGAP5 ANKRD12 DDX24

3.50e-0419931306c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

ANKRD12 STXBP1 DDX24

3.55e-04200313c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellsevere-MAIT|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GTF3A DDX24 PRF1

3.55e-042003131daf43f1bdd49585dce5e957820554d7f3c1bd4a
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANKRD12 DDX24 PRF1

3.55e-04200313e642b3e25b2884b2bc6114683fa7ac39d6559bf8
ToppCellsevere|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GTF3A KRR1 DDX24

3.55e-04200313accc618d6b960bff30cb531c1226295bfc8650f6
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-MAIT|COVID-19_Severe / Disease, condition lineage and cell class

GTF3A DDX24 PRF1

3.55e-04200313b8cfccecff9900aee323c40e771c94e560b8c488
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP18 SGK1 EGFL6

3.55e-0420031326f07d271e984f375145e4c10528fba44a5811e1
ToppCellPBMC-Severe-Lymphocyte-T/NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANKRD12 DDX24 PRF1

3.55e-0420031373b91cb66c375b44e852404a4a445cf2b9595aee
ToppCellsevere-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GTF3A DDX24 PRF1

3.55e-042003138a849d0ef244aa2666da2d31bd0731fb04e40911
ToppCellCOVID-19|World / Disease, condition lineage and cell class

BOD1L1 ANKRD12 DDX24

3.55e-042003137dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP18 SGK1 EGFL6

3.55e-04200313c3637827ceba16b0d7956c280dd2ddbc8b1ba55e
ToppCellCOVID-19-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

ANKRD12 ARHGAP18 SGK1

3.55e-04200313a60346c5ea7a3dae1ad3c5dc6c6eca65b64c6888
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANKRD12 DDX24 PRF1

3.55e-04200313bb05d2d10c924202f78fa1bd271f60cbbf224108
ToppCellmetastatic_Brain-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

ELL2 ARHGAP18 SGK1

3.55e-04200313bfb54a8ce44caf01083c6567b236395c6ee1d47a
ToppCellSigmoid-T_cell-Activated_CD4_T|T_cell / Region, Cell class and subclass

ZBTB10 ARHGAP5 KRR1

3.55e-042003139c21e6b8d4f8e526950adacf9cc45a5e86d81c1f
ToppCellsevere-CD4+_Tcm|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD12 GTF3A DDX24

3.55e-04200313e83558090a079dd9e40e0d3b5d9917fbd2695ec4
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BOD1L1 ANKRD12 DDX24

3.55e-0420031312f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19_Severe-Lymphoid_T/NK|COVID-19_Severe / Disease group, lineage and cell class

ANKRD12 DDX24 PRF1

3.55e-042003139fc818bf5c9133fc2fece47980e71fd3f8603558
ToppCellPBMC-Severe-Lymphocyte-T/NK|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKRD12 DDX24 PRF1

3.55e-04200313f1c8780d64b58b6fb84fffbc27f0ad337b1a6e56
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A

BBX FEZ2 DDX24 TFAM HMGXB4

4.09e-061793154585_DN
Diseaseleptin measurement

ZNF800 TFAM

3.29e-0381312EFO_0005000
Diseasebody surface area

GTF3A UNCX FEZ2 PRR13

4.41e-03643314EFO_0022196
Diseasethyroid stimulating hormone measurement

ZBTB10 FAM227B SGK1

4.66e-03323313EFO_0004748
Diseaseobesity (is_marker_for)

AHI1 TFAM

5.06e-03101312DOID:9970 (is_marker_for)
DiseaseMental Retardation, Psychosocial

RABL6 AHI1

9.37e-03139312C0025363
DiseaseProfound Mental Retardation

RABL6 AHI1

9.37e-03139312C0020796
DiseaseMental deficiency

RABL6 AHI1

9.37e-03139312C0917816

Protein segments in the cluster

PeptideGeneStartEntry
KKYHKKKKIMLSDEM

FAM227B

126

Q96M60
AHLSKKEKKKLKKQM

ABCF1

251

Q8NE71
KKLLAHKNSMKKKAK

EGFL6

281

Q8IUX8
SMSHKKSKKKSKKHK

ELL2

456

O00472
KSKKKSKKHKEKDQI

ELL2

461

O00472
KKKKKKSKMDRHGND

BBX

451

Q8WY36
KTHSDLMREKKKLKK

AHI1

21

Q8N157
LKEEKLHAKKMKLTK

CSRNP2

126

Q9H175
KKMDKEGKTLKKHKL

ANKRD12

641

Q6UB98
AKKKHLDKKRKLKEM

BMS1

821

Q14692
EKAAKKKSKHKKSKD

RABL6

666

Q3YEC7
KKSKHKKSKDKEEGK

RABL6

671

Q3YEC7
SHKKLKLTKMRAKKK

KIAA2026

671

Q5HYC2
AKACEEKKKKHKMTA

PRF1

276

P14222
KKHSKEKKGSKKDIK

CYLC1

496

P35663
IALKMEADEKKKKKK

KRR1

366

Q13601
KKKKDKEKHKEKRHS

HMGXB4

326

Q9UGU5
DKKMQKKMKKAHKKM

PRR13

106

Q9NZ81
KKMKKAHKKMHKHQK

PRR13

111

Q9NZ81
KEKKEKTEKKFDHSK

BOD1L1

336

Q8NFC6
LHKKHTKKMDKTAKL

DDX24

521

Q9GZR7
GMKHVKKEKAEKLEK

SCO1

111

O75880
EKKKWKDLKLMKKLE

SPOUT1

31

Q5T280
KEHKETAKKKKKLKN

FEZ2

271

Q9UHY8
IAAKKKMKKHKNKSE

UTP20

2741

O75691
KKAILKKKEEKHIMS

SGK1

131

O00141
ELDDKKMKKKTHKVK

ARHGAP5

1221

Q13017
KMKKKTHKVKEDKKQ

ARHGAP5

1226

Q13017
THKVKEDKKQKKKTK

ARHGAP5

1231

Q13017
KHLKRKAMTKKKELT

TFAM

136

Q00059
GEKIMHDVIKKVKKK

STXBP1

11

P61764
HKKDKRAMKKLLKKM

ARHGAP18

541

Q8N392
EKKATHKEKIEKKEK

TRDN

181

Q13061
KVHKKKMEELKKYIE

ZNF800

251

Q2TB10
HDPDKKKMKLKVKKS

GTF3A

301

Q92664
VHKKDKKYKCMVCKK

ZBTB10

771

Q96DT7
ELEKMEKKKRKHEKK

UNCX

196

A6NJT0