Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	methyl-CpG binding	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	2.75e-06	31	145	5	GO:0008327
GeneOntologyBiologicalProcess	DNA methylation-dependent constitutive heterochromatin formation	MBD3L5 MBD3L2 BEND3 MBD3L3 MBD3L4 MBD3L2B	6.42e-07	44	146	6	GO:0006346
GeneOntologyBiologicalProcess	facultative heterochromatin formation	MBD3L5 MBD3L2 BEND3 MBD3L3 MBD3L4 MBD3L2B	2.47e-06	55	146	6	GO:0140718
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO1 NOMO2 NOMO3	2.83e-05	9	146	3	GO:0160063
GeneOntologyBiologicalProcess	cardiac septum development	PCSK5 ADAMTS19 MAML1 CHD7 NRP2 RBPJ HECTD1	4.78e-05	134	146	7	GO:0003279
GeneOntologyBiologicalProcess	mitochondrial NAD transmembrane transport	SLC25A51 SLC25A52	4.98e-05	2	146	2	GO:1990549
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO1 NOMO2 NOMO3	2.72e-05	9	146	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO1 NOMO2 NOMO3	1.15e-04	14	146	3	GO:0072379
GeneOntologyCellularComponent	MAML1-RBP-Jkappa- ICN1 complex	MAML1 RBPJ	1.45e-04	3	146	2	GO:0002193
Domain	MeCpG-bd_2/3_C_dom	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.10e-07	7	142	4	IPR025884
Domain	MBD2/MBD3_p55-bd	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.10e-07	7	142	4	IPR032343
Domain	MBDa	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.10e-07	7	142	4	PF16564
Domain	MBD_C	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.10e-07	7	142	4	PF14048
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.71e-06	4	142	3	PF09430
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.71e-06	4	142	3	IPR019008
Domain	zf-C2H2_6	ZNF573 ZNF560 ZNF658 ZNF568 PRDM2 ZNF10 ZNF182 ZNF283 ZNF737 ZNF107 ZFP62 ZNF681	5.12e-06	314	142	12	PF13912
Domain	-	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 PRDM2 ZNF462 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	1.62e-05	679	142	17	3.30.160.60
Domain	KRAB	ZNF793 ZNF573 ZNF560 ZNF658 ZNF568 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF681	1.91e-05	358	142	12	PS50805
Domain	KRAB	ZNF793 ZNF573 ZNF560 ZNF658 ZNF568 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF681	1.91e-05	358	142	12	PF01352
Domain	Znf_C2H2/integrase_DNA-bd	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 PRDM2 ZNF462 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	2.14e-05	694	142	17	IPR013087
Domain	Carb-bd-like_fold	NOMO1 NOMO2 NOMO3	2.34e-05	8	142	3	IPR013784
Domain	KRAB	ZNF793 ZNF573 ZNF560 ZNF658 ZNF568 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF681	2.57e-05	369	142	12	SM00349
Domain	KRAB	ZNF793 ZNF573 ZNF560 ZNF658 ZNF568 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF681	2.64e-05	370	142	12	IPR001909
Domain	Znf_C2H2-like	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 PRDM2 ZNF462 ZNF10 KAT7 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	3.47e-05	796	142	18	IPR015880
Domain	Znf_C2H2	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 PRDM2 ZNF462 ZNF10 KAT7 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	4.01e-05	805	142	18	IPR007087
Domain	ZnF_C2H2	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 PRDM2 ZNF462 ZNF10 KAT7 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	4.21e-05	808	142	18	SM00355
Domain	zf-C2H2	ZNF793 ZNF573 ZNF560 ZNF658 ZNF568 PRDM2 ZNF462 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	7.64e-05	693	142	16	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 PRDM2 ZNF462 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	8.44e-05	775	142	17	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 PRDM2 ZNF462 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	8.71e-05	777	142	17	PS00028
Domain	CarboxyPept_regulatory_dom	NOMO1 NOMO2 NOMO3	1.16e-04	13	142	3	IPR014766
Domain	-	NOMO1 NOMO2 NOMO3	1.16e-04	13	142	3	2.60.40.1120
Domain	CarboxyPept-like_regulatory	NOMO1 NOMO2 NOMO3	2.71e-04	17	142	3	IPR008969
Domain	ADAM_Cys-rich	ADAMTS19 ADAM7 ADAM22	1.10e-03	27	142	3	IPR006586
Domain	ACR	ADAMTS19 ADAM7 ADAM22	1.10e-03	27	142	3	SM00608
Domain	RBD	RGS12 TIAM2	1.18e-03	7	142	2	SM00455
Domain	RBD_dom	RGS12 TIAM2	1.18e-03	7	142	2	IPR003116
Domain	RBD	RGS12 TIAM2	1.18e-03	7	142	2	PS50898
Pubmed	MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	7.53e-12	6	147	5	12504854
Pubmed	Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	7.53e-12	6	147	5	18942147
Pubmed	MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	3.66e-09	15	147	5	15701600
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO1 NOMO2 NOMO3	7.40e-08	3	147	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO1 NOMO2 NOMO3	7.40e-08	3	147	3	25576386
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO1 NOMO2 NOMO3	2.95e-07	4	147	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO1 NOMO2 NOMO3	2.95e-07	4	147	3	9267806
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	VRK2 DNAJC13 WDR7 ADAM22 FAM83B NEO1 IGF2R ANO6 TMEM131L FAM135A UVRAG ZC3HAV1	1.72e-06	504	147	12	34432599
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	CAT CPOX NDUFA8 NOMO1 NRP2 NEDD4 PDIA4 NEO1 RBM12 IGF2R NOMO2 MRC2 ASXL3 SMARCC2 PLAT LTBP3 NOMO3 ACSL5 SYNCRIP ZC3HAV1	3.39e-06	1451	147	20	30550785
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO1 NOMO2 NOMO3	4.08e-06	8	147	3	15257293
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	DNAJC13 WDR7 INSR MAML1 BEND3 DNM1L FAM83B NEO1 IGF2R ANO6 FAM135A CDON NOL8 ZC3HAV1	5.92e-06	777	147	14	35844135
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO1 NOMO2 NOMO3	6.10e-06	9	147	3	36261522
Pubmed	Disruption of parental-specific expression of imprinted genes in uniparental fetuses.	MAGEL2 PEG10 SLC38A4 IGF2R	6.70e-06	29	147	4	16987518
Pubmed	Human transcription factor protein interaction networks.	LIMA1 SOBP PEG10 PSMB7 MAML1 BEND3 CHD7 NDUFA8 ZEB2 PRDM2 PDIA4 ZNF462 RBM12 RBPJ SMARCC2 PPIL2 ZNF107 SYNCRIP ZC3HAV1	1.01e-05	1429	147	19	35140242
Pubmed	An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.	ZEB2 NOMO1 NOMO2 NOMO3	1.14e-05	33	147	4	30783098
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	EFCAB5 LIMA1 ZNF658 RBBP8 FAM178B ADAM7 SKIDA1 ANKS1B BEND3 CAT CPOX ZEB2 FER1L6 PDIA4 SEPHS1 PHF20L1 SMARCC2 TOP1MT SYNCRIP	1.15e-05	1442	147	19	35575683
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO1 NOMO2 NOMO3	1.19e-05	11	147	3	32820719
Pubmed	Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.	APPBP2 PSMB7 RNF25 RBM12 CYB5R1 SYNCRIP	1.53e-05	124	147	6	23000965
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAPK8IP1 LIMA1 DNAJC13 WDR7 ANKS1B DNM1L CHD7 GIT2 ZEB2 ADAM22 NEDD4 ZNF462 IGF2R SMARCC2 PRKD1	1.53e-05	963	147	15	28671696
Pubmed	Identification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1. A cytoplasmic RNA-binding protein.	INSR SYNCRIP	1.77e-05	2	147	2	11994298
Pubmed	The human papillomavirus type 8 E6 protein interferes with NOTCH activation during keratinocyte differentiation.	MAML1 RBPJ	1.77e-05	2	147	2	23365452
Pubmed	Tissue plasminogen activator is a ligand of cation-independent mannose 6-phosphate receptor and consists of glycoforms that contain mannose 6-phosphate.	IGF2R PLAT	1.77e-05	2	147	2	33859256
Pubmed	Epistasis between IGF2R and ADAMTS19 polymorphisms associates with premature ovarian failure.	ADAMTS19 IGF2R	1.77e-05	2	147	2	24014609
Pubmed	SLC25A51 is a mammalian mitochondrial NAD+ transporter.	SLC25A51 SLC25A52	1.77e-05	2	147	2	32906142
Pubmed	HNRNP Q suppresses polyglutamine huntingtin aggregation by post-transcriptional regulation of vaccinia-related kinase 2.	VRK2 SYNCRIP	1.77e-05	2	147	2	30488434
Pubmed	Linkage mapping of autosomal dominant retinitis pigmentosa (RP1) to the pericentric region of human chromosome 8.	PLAT RP1	1.77e-05	2	147	2	1783394
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	LIMA1 DNAJC13 SLC38A4 CHD7 SLC25A51 NEDD4 ZNF462 RBPJ SLC25A52 HECTD1 SYNCRIP	1.89e-05	536	147	11	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	LIMA1 DNAJC13 SLC38A4 CHD7 SLC25A51 NEDD4 ZNF462 RBPJ SLC25A52 HECTD1 SYNCRIP	1.95e-05	538	147	11	10512203
Pubmed	Interaction network of human early embryonic transcription factors.	SOBP MAML1 CHD7 ZEB2 PRDM2 PDIA4 ZNF462 ASXL3 SMARCC2	1.99e-05	351	147	9	38297188
Pubmed	Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation.	DNAJC13 CAT MRC2 SYNCRIP	2.49e-05	40	147	4	16210410
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	VRK2 WDR7 FAM83B IGF2R MRC2 FAM135A UVRAG ZC3HAV1	3.07e-05	285	147	8	34369648
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MAGEA1 LIMA1 VRK2 DNAJC13 PEG10 DNM1L CAT MELK IVNS1ABP PDIA4 IGF2R NOMO2 SMARCC2 HECTD1 PLS3 SYNCRIP ZC3HAV1	3.67e-05	1297	147	17	33545068
Pubmed	Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.	WDR7 ZNF462 UVRAG	3.98e-05	16	147	3	16096065
Pubmed	A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters.	MAML1 RBPJ	5.31e-05	3	147	2	11390662
Pubmed	The mitochondrial NAD+ transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions.	SLC25A51 SLC25A52	5.31e-05	3	147	2	35932995
Pubmed	An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation.	ACE PLAT	5.31e-05	3	147	2	15119966
Pubmed	Direct inhibition of the NOTCH transcription factor complex.	MAML1 RBPJ	5.31e-05	3	147	2	19907488
Pubmed	PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization.	PACS1 IGF2R	5.31e-05	3	147	2	9695949
Pubmed	A novel heterogeneous nuclear ribonucleoprotein-like protein interacts with NS1 of the minute virus of mice.	IVNS1ABP SYNCRIP	5.31e-05	3	147	2	9847309
Pubmed	Mutational and energetic studies of Notch 1 transcription complexes.	MAML1 RBPJ	5.31e-05	3	147	2	18155729
Pubmed	Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance.	FLT3 FGR	5.31e-05	3	147	2	31790499
Pubmed	Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex.	MAML1 RBPJ	5.31e-05	3	147	2	12644465
Pubmed	Polymorphisms of EDNRB, ATG, and ACE genes in salt-sensitive hypertension.	ACE EDNRB	5.31e-05	3	147	2	18758497
Pubmed	Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling.	INSR IGF2R	5.31e-05	3	147	2	32167474
Pubmed	ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.	ZEB2 JAG2	5.31e-05	3	147	2	38485033
Pubmed	Conformational locking upon cooperative assembly of notch transcription complexes.	MAML1 RBPJ	5.31e-05	3	147	2	22325781
Pubmed	Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse.	INSR IGF2R	5.31e-05	3	147	2	2852162
Pubmed	Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.	PCSK5 LTBP3	5.31e-05	3	147	2	21700711
Pubmed	Hes1 suppresses acute myeloid leukemia development through FLT3 repression.	FLT3 RBPJ	5.31e-05	3	147	2	25234168
Pubmed	Insulin-like growth factor II (IGF-II).	INSR IGF2R	5.31e-05	3	147	2	9722981
Pubmed	Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.	MAML1 RBPJ	5.31e-05	3	147	2	16530044
Pubmed	The T6 translocation in the mouse: its use in trisomy mapping, centromere localization, and cytological identification of linkage group 3.	EDNRB SLC45A2	5.31e-05	3	147	2	5055128
Pubmed	Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.	NEDD4 HECTD1	5.31e-05	3	147	2	22431752
Pubmed	Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.	VRK2 GABBR1	5.31e-05	3	147	2	27922604
Pubmed	Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line.	MAML1 RBPJ	5.31e-05	3	147	2	11997524
Pubmed	A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.	APPBP2 PSMB7 RNF25 RBM12 CYB5R1 SYNCRIP	6.85e-05	162	147	6	21890473
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	VRK2 MAML1 ZFAND5 CHD7 MELK PDIA4 NEO1 IGF2R THYN1 NOMO2 TMEM131L HECTD1	7.06e-05	733	147	12	34672954
Pubmed	Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.	GNE DNM1L ECT2 PHF20L1 CDON NOL8	7.58e-05	165	147	6	16107646
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	MAML1 ACE NOMO1 PDIA4 IGF2R NOMO2 SMARCC2 PLS3 NOMO3	8.71e-05	425	147	9	24999758
Pubmed	The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex.	MAGEA1 MAGEL2 PHF7	9.30e-05	21	147	3	25590999
Pubmed	Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex.	MAML1 RBPJ	1.06e-04	4	147	2	20118921
Pubmed	Association of polymorphisms in FLT3, EGFR, ALOX5, and NEIL3 with glioblastoma in the Han Chinese population.	FLT3 ALOX5	1.06e-04	4	147	2	24005813
Pubmed	Regulation of insulin-like growth factor receptors by Ubiquilin1.	INSR IGF2R	1.06e-04	4	147	2	29054976
Pubmed	Ubiquitination of Notch1 is regulated by MAML1-mediated p300 acetylation of Notch1.	MAML1 RBPJ	1.06e-04	4	147	2	22100894
Pubmed	The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis.	MAML1 RBPJ	1.06e-04	4	147	2	16510869
Pubmed	The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.	INSR PLAT	1.06e-04	4	147	2	9013772
Pubmed	Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.	APPBP2 PSMB7 RNF25 RBM12 CYB5R1 SYNCRIP	1.22e-04	180	147	6	21139048
Pubmed	Upregulation of imprinted genes in mice: an insight into the intensity of gene expression and the evolution of genomic imprinting.	PEG10 SLC38A4 IGF2R	1.40e-04	24	147	3	20168089
Pubmed	Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.	SPINK9 NOMO1 NOMO2 NOMO3	1.50e-04	63	147	4	31266804
Pubmed	Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.	INSR IGF2R	1.76e-04	5	147	2	9281335
Pubmed	Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS.	FGR ALOX5	1.76e-04	5	147	2	24860872
Pubmed	Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity.	MAML1 RBPJ	1.76e-04	5	147	2	26108681
Pubmed	[Cancer-testis genes in colon cancer].	MAGEA1 PRSS50	1.76e-04	5	147	2	28631709
Pubmed	Activity-Based Probes for HECT E3 Ubiquitin Ligases.	NEDD4 HECTD1	1.76e-04	5	147	2	28425671
Pubmed	3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling.	JAG2 RBPJ	1.76e-04	5	147	2	30244870
Pubmed	Differentiation of Mouse Enteric Nervous System Progenitor Cells Is Controlled by Endothelin 3 and Requires Regulation of Ednrb by SOX10 and ZEB2.	ZEB2 EDNRB	1.76e-04	5	147	2	28063956
Pubmed	The intracellular domain of Jagged-1 interacts with Notch1 intracellular domain and promotes its degradation through Fbw7 E3 ligase.	MAML1 RBPJ	1.76e-04	5	147	2	21820430
Pubmed	PLK1-mediated phosphorylation of PPIL2 regulates HR via CtIP.	RBBP8 PPIL2	1.76e-04	5	147	2	36092721
Pubmed	Epistatic effects of polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels.	ACE PLAT	1.76e-04	5	147	2	17207964
Pubmed	A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking.	PACS1 IGF2R	1.76e-04	5	147	2	16977309
Pubmed	Insulin and insulin-like growth factor resistance in alcoholic neurodegeneration.	INSR IGF2R	1.76e-04	5	147	2	18616667
Pubmed	Deubiquitinase USP10 regulates Notch signaling in the endothelium.	MAML1 RBPJ	1.76e-04	5	147	2	30975888
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	BEND3 CHD7 PARP14 ZEB2 ZNF462 KAT7 RBPJ SMARCC2 ASCC3	1.82e-04	469	147	9	27634302
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	MAPK8IP1 LIMA1 NEDD4 SMARCC2	1.91e-04	67	147	4	29254152
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	VRK2 DNAJC13 PEG10 FAM83B NOMO1 PDIA4 NEO1 IGF2R NOMO2 ANO6 TMEM131L ASCC3 FAM135A PLS3 NOL8 SYNCRIP ZC3HAV1	1.92e-04	1487	147	17	33957083
Pubmed	Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes.	DNM1L ADAM22 SLC15A5	2.01e-04	27	147	3	24550280
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RBBP8 MAML1 CHD7 GIT2 FAM83B SEPHS1 NOMO2 RBPJ PPIL2 FAM135A	2.12e-04	588	147	10	38580884
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	DNM1L CHD7 ZNF568 TIAM2 PRDM2 PDIA4 KAT7 PACS1 ZNF182 IGF2R RBPJ TMEM131L IL17RD FAM135A	2.15e-04	1084	147	14	11544199
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	WDR7 DNM1L PACS1 NEO1 CADPS PLS3	2.28e-04	202	147	6	33601422
Pubmed	Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases.	INSR PLAT	2.63e-04	6	147	2	8559144
Pubmed	Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics.	MAML1 RBPJ	2.63e-04	6	147	2	35821235
Pubmed	CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex.	MAML1 RBPJ	2.63e-04	6	147	2	9874765
Pubmed	Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.	IGF2R ALOX5	2.63e-04	6	147	2	32234475
Pubmed	Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2.	FLT3 FGR	2.63e-04	6	147	2	16684964
Pubmed	RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.	RBBP8 RBPJ	2.63e-04	6	147	2	16287852
Pubmed	Prevalence of genetic risk factors for coronary artery disease in Corsica island (France).	ACE PLAT	2.63e-04	6	147	2	16248996
Pubmed	Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.	MAML1 RBPJ	2.63e-04	6	147	2	19838210
Pubmed	TRBP maintains mammalian embryonic neural stem cell properties by acting as a novel transcriptional coactivator of the Notch signaling pathway.	MAML1 RBPJ	2.63e-04	6	147	2	28174252
Pubmed	Organ-specific defects in insulin-like growth factor and insulin receptor signaling in late gestational asymmetric intrauterine growth restriction in Cited1 mutant mice.	INSR IGF2R	2.63e-04	6	147	2	21486933
Pubmed	Influence of placental mannose/n-acetyl glucosamine-binding proteins on the interaction of insulin and insulin-like growth factors with their receptors.	INSR IGF2R	2.63e-04	6	147	2	22082268
Cytoband	19p13.2	MBD3L5 ZNF560 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	1.02e-04	229	147	6	19p13.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF793 ZNF573 ZNF560 ZNF658 ZEB2 ZNF568 ZNF462 ZNF10 ZNF182 ZNF544 ZNF283 ZNF737 ZNF534 ZNF107 ZFP62 ZNF681	1.94e-06	718	100	16	28
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	PCSK5 CRISPLD2 ANKS1B ZEB2 ADAM22 ZNF462 LTBP3 PLS3	3.48e-07	200	147	8	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	PARP14 ZEB2 PRDM2 ZNF10 IGF2R TMEM131L ZC3HAV1	3.09e-06	188	147	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Skin-Telogen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 RBBP8 RGS12 IVNS1ABP FCGBP OSGIN2 ACSL5	3.09e-06	188	147	7	8cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCell	IPF-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	PCSK5 LIMA1 NOMO1 JAG2 NOMO2 MRC2 NOMO3	3.55e-06	192	147	7	e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCell	BLOOD--(0)_NK_cells_(CD56dim-like)\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PCSK5 ZEB2 FCRL6 PLAAT3 IGF2R FGR KLRC1	4.21e-06	197	147	7	4c15b3386b89191af9332738e597549e2305de26
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZCCHC24 PCSK5 CRISPLD2 NEDD4 MRC2 PLAT LTBP3	4.35e-06	198	147	7	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC24 LIMA1 CHD7 EDNRB PDIA4 PLAT MIR9-1HG	4.65e-06	200	147	7	439265194cb08d1373296bf8684cc31294cecb20
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PCSK5 CRISPLD2 ANKS1B ZEB2 ADAM22 ZNF462 LTBP3	4.65e-06	200	147	7	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Sepsis-ICU-NoSEP-Myeloid-cDC1\|ICU-NoSEP / Disease, condition lineage and cell class	FLT3 LIMA1 CAT CLIC2 MRC2 TOP1MT ACSL5	4.65e-06	200	147	7	511e642575182fb678df6791ee6539b0ced3eb17
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-OPC_related-OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC24 LIMA1 CHD7 EDNRB PDIA4 PLAT MIR9-1HG	4.65e-06	200	147	7	0450a79c5fae5ccacdb990ae674e4734ef0c3691
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC24 LIMA1 EDNRB MRC2 PHF11 PLAT MIR9-1HG	4.65e-06	200	147	7	25b573f4427ecafe050ca90bea459f1b25b451cf
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCRL6 CADPS PRSS50 SLC45A2 AGBL1 KLRC1	6.90e-06	139	147	6	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCRL6 CADPS PRSS50 SLC45A2 AGBL1 KLRC1	6.90e-06	139	147	6	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM186B TNNI3K PRSS50 IL17RD AGBL1	2.35e-05	103	147	5	3f4e4600c8a9af3534479ca19905c3d31c4c55bb
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SKIDA1 ZNF568 NRP2 CADPS OSGIN2 ALOX5	2.72e-05	177	147	6	86c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF658 SLC38A4 ADAM22 PLAAT3 CLIC2 TTC9	2.72e-05	177	147	6	6248c0dcad302de61a66163ee84b3b79096150d7
ToppCell	ICU-NoSEP-Myeloid-cDC1\|ICU-NoSEP / Disease, Lineage and Cell Type	FLT3 ENO4 CLIC2 MRC2 TOP1MT ACSL5	2.72e-05	177	147	6	33cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBBP8 RGS12 IVNS1ABP JAG2 FCGBP OSGIN2	3.70e-05	187	147	6	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 ZEB2 ADAM22 EDNRB NRP2 MRC2	3.93e-05	189	147	6	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 ZEB2 ADAM22 EDNRB NRP2 MRC2	4.04e-05	190	147	6	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 ZEB2 ADAM22 EDNRB NRP2 MRC2	4.04e-05	190	147	6	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZCCHC24 MRC2 PLAT TTC9 LTBP3 CDON	4.16e-05	191	147	6	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	PCSK5 LIMA1 ZFAND5 NOMO1 NOMO2 NOMO3	4.16e-05	191	147	6	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-OPC_related-OPC\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC24 LIMA1 FAM178B EDNRB PLAT CTSO	4.29e-05	192	147	6	5d9bc234f01c73b2531edf8960588d5b6cf260a7
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 ACE MRC2 PLAT PRKD1 IL17RD	4.29e-05	192	147	6	be75783d9578974b662e1cb13bd3442a921fd50a
ToppCell	facs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS12 IVNS1ABP PDIA4 JAG2 FCGBP ACSL5	4.29e-05	192	147	6	ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-OPC_related\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC24 LIMA1 FAM178B EDNRB PLAT CTSO	4.29e-05	192	147	6	e6d115143ced6a0d9fe7c98acd3f730bac83f66b
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 ACE MRC2 PLAT PRKD1 IL17RD	4.29e-05	192	147	6	4fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC24 LIMA1 EDNRB NRP2 PLAT PLS3	4.41e-05	193	147	6	e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC24 LIMA1 EDNRB NRP2 PLAT PLS3	4.41e-05	193	147	6	b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	CRISPLD2 ADAMTS19 SOBP ANKS1B EDNRB MRC2	4.41e-05	193	147	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	INSR EDNRB NRP2 IVNS1ABP PLAT ACSL5	4.41e-05	193	147	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 CAT CALHM6 CLIC2 RBPJ UVRAG	4.54e-05	194	147	6	6af2971d83f5ad6aed16d0ceb8bfc52f3947bc10
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 CAT CALHM6 CLIC2 RBPJ UVRAG	4.54e-05	194	147	6	5c60670ec24470225fabaa6071fdb4ef6e579840
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ZEB2 FCRL6 IVNS1ABP IGF2R FGR KLRC1	4.54e-05	194	147	6	335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell	Nasal_Brush\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	LIMA1 PRSS22 PARP14 FER1L6 FCGBP TTC9	4.67e-05	195	147	6	7509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCell	COVID-19-Lymphoid-CD8_T_cells\|Lymphoid / Condition, Lineage and Cell class	ZEB2 FCRL6 PLAAT3 FGR KLRC1 MIR9-1HG	4.67e-05	195	147	6	d4c70a462b98963e78f4e2659574bc350f8ffe1a
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	RBBP8 FAM83B IVNS1ABP PRKD1 RP1 FAM135A	4.81e-05	196	147	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ZEB2 FCRL6 IVNS1ABP IGF2R FGR KLRC1	4.81e-05	196	147	6	07b557b8530c19ca5b31ad2eac00c36ef1939266
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGEL2 SOBP FER1L6 FAM83B JAG2 ASXL3	4.95e-05	197	147	6	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT3 CALHM6 ZEB2 NRP2 RBPJ FGR	4.95e-05	197	147	6	555ea43eccc3eb22be230c27e13d8b3b64c2a61f
ToppCell	BLOOD--(0)_NK_cell\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PCSK5 FCRL6 PLAAT3 IGF2R FGR KLRC1	4.95e-05	197	147	6	ce35c3ba6db897235d0107fa7dadc5013bf4da24
ToppCell	COVID-19_Severe-NK\|COVID-19_Severe / Disease condition and Cell class	ZEB2 FCRL6 PLAAT3 IGF2R FGR KLRC1	5.09e-05	198	147	6	742c4d6016cfa48444a5919a885ab8d02cad7e18
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LIMA1 PRSS22 RGS12 FAM83B NRP2 PLAT	5.09e-05	198	147	6	77517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCell	(0)_NK_FCGR3Apos\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PCSK5 ZEB2 FCRL6 IGF2R FGR KLRC1	5.09e-05	198	147	6	13f10f9233fc1523f0da2d9d59f3ced9c51a603a
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK5 CHD7 EDNRB PLAAT3 PLS3 MIR9-1HG	5.09e-05	198	147	6	5b9a7b9f53a3d9cf8d6e6a7c1c94514b22cf9fa8
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMA1 RBBP8 NEDD4 IVNS1ABP JAG2 PLS3	5.09e-05	198	147	6	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLT3 CAT CALHM6 CLIC2 FGR ALOX5	5.09e-05	198	147	6	da36c1bb62fdd1da7aca9c5115432a87fb48adb0
ToppCell	metastatic_Lymph_Node-T/NK_cells-NK\|T/NK_cells / Location, Cell class and cell subclass	PCSK5 ZEB2 FCRL6 IGF2R FGR KLRC1	5.09e-05	198	147	6	cc4c1306683b801c1cb0adc01951aa6e3d73626f
ToppCell	COVID-19_Moderate-NK\|COVID-19_Moderate / disease group, cell group and cell class	ZEB2 FCRL6 PLAAT3 IGF2R FGR KLRC1	5.23e-05	199	147	6	e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	LIMA1 ZEB2 TIAM2 IGF2R PLS3 MIR9-1HG	5.23e-05	199	147	6	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PCSK5 CRISPLD2 ANKS1B ZEB2 ADAM22 LTBP3	5.23e-05	199	147	6	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Control-NK\|Control / Disease condition and Cell class	ZEB2 FCRL6 PLAAT3 IGF2R FGR KLRC1	5.23e-05	199	147	6	f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PCSK5 ANKS1B ZEB2 ADAM22 TIAM2 LTBP3	5.23e-05	199	147	6	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related-OPC\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	LIMA1 CHD7 ECT2 EDNRB PLAT MIR9-1HG	5.38e-05	200	147	6	02594c1edbc9f2cf831639cd83363abd2551cb94
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	LIMA1 CHD7 ECT2 EDNRB PLAT MIR9-1HG	5.38e-05	200	147	6	46521d83b917b0357601db8783c8da6b73730d60
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	PCSK5 CRISPLD2 ANKS1B ZEB2 MRC2 LTBP3	5.38e-05	200	147	6	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LIMA1 ECT2 MELK ZNF462 PLAT MIR9-1HG	5.38e-05	200	147	6	38e681997913fcbc93f4e1715820e53844376eab
ToppCell	Sepsis-Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, condition lineage and cell class	FLT3 LIMA1 ZNF462 CLIC2 MRC2 FAM135A	5.38e-05	200	147	6	cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCell	COVID-19_Mild-NK\|COVID-19_Mild / Disease condition and Cell class	ZEB2 FCRL6 PLAAT3 IGF2R FGR KLRC1	5.38e-05	200	147	6	b586b0f1127293c2f8529be16b24229359041da2
ToppCell	mild-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PEG10 CHD7 PARP14 PRDM2 ZNF107 UVRAG	5.38e-05	200	147	6	222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell	Sepsis-Int-URO-Myeloid-cDC1\|Int-URO / Disease, condition lineage and cell class	FLT3 LIMA1 CAT ZNF462 CLIC2 TOP1MT	5.38e-05	200	147	6	77479f733cc4ce62a07ab33d5dc2d41c911c74fc
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 MBD3L2 CALHM6 FAM83B CLIC2	9.19e-05	137	147	5	86c32cd26fe3b23c1dcd8ace580231c5a6ec6d9e
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 MBD3L2 CALHM6 FAM83B CLIC2	9.19e-05	137	147	5	8989103606b15dff300e44c1590cd867b3cf7833
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	SOBP CALHM6 EDNRB RBPJ ACSL5	1.09e-04	142	147	5	0e0f8bb956ff89dc98e8fa56f8acac33e01a26dd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM186B CADPS THAP3 FGR ALOX5	1.54e-04	153	147	5	83942ef63d21725fa15ed5a91481d1f9936e8f11
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CRISPLD2 FCRL6 NOMO1 KLRC1 NOMO3	1.54e-04	153	147	5	4eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CRISPLD2 FCRL6 NOMO1 KLRC1 NOMO3	1.54e-04	153	147	5	26b5b45c117d155b028d298a0b93e16d343dca97
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CRISPLD2 FCRL6 NOMO1 KLRC1 NOMO3	1.54e-04	153	147	5	0f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCell	PBMC-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	MAML1 PARP14 PHF11 MIR9-1HG ZC3HAV1	1.69e-04	156	147	5	9b6c5bcac516a62bcc1f5be32ffa8c92735ef0bc
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLT3 SOBP CLIC2 MRC2 TOP1MT	1.74e-04	157	147	5	19c0599a669803c4db1f174de1ce755e562a50a3
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PCSK5 ZEB2 FCRL6 EDNRB FGR	1.79e-04	158	147	5	1bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MAPK8IP1 ZNF462 NEO1 TTC9 PLS3	2.01e-04	162	147	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF793 ANKS1B ZNF283 PHF11 ACSL5	2.01e-04	162	147	5	6ffcf369d954c20ce036aa1d072cee4e205f728e
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF793 ANKS1B ZNF283 PHF11 ACSL5	2.01e-04	162	147	5	bcbf7f80a2a1c80def795e345f16cf16e8b9d03b
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 LIMA1 CLIC2 MRC2 TOP1MT	2.07e-04	163	147	5	a09449a502627aa369db600dba5bda93de7ce5c0
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ECT2 ANO6 FGR ALOX5 GABBR1	2.07e-04	163	147	5	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PARP14 ZEB2 PRDM2 UVRAG ALOX5	2.07e-04	163	147	5	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SKIDA1 ZEB2 KLRC1 MIR9-1HG ZC3HAV1	2.07e-04	163	147	5	11cc18f36604d9a5f4e7fb8626a8f0fb141da5e1
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ECT2 ANO6 FGR ALOX5 GABBR1	2.07e-04	163	147	5	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	Int-URO-Myeloid-cDC1\|Int-URO / Disease, Lineage and Cell Type	FLT3 LIMA1 ZNF462 CLIC2 TOP1MT	2.13e-04	164	147	5	f4628a7ff0dc765a5337ab499b3d61fc25573a16
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 LIMA1 CLIC2 MRC2 TOP1MT	2.13e-04	164	147	5	ed888b55d9c685096fd785878fcb264f4fee88d6
ToppCell	Club-club-12\|World / Class top	ZCCHC24 FAM186B FER1L6 FCGBP PLAT	2.19e-04	165	147	5	9b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MAPK8IP1 ZNF462 NEO1 TTC9 PLS3	2.25e-04	166	147	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Control / Condition, Lineage and Cell class	CRISPLD2 CALHM6 PARP14 EDNRB PLAT	2.32e-04	167	147	5	ab6029ba037b6a499da8758864c44e174cde5587
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	CRISPLD2 CALHM6 PARP14 EDNRB PLAT	2.32e-04	167	147	5	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT3 IVNS1ABP PHF11 RBPJ UVRAG	2.45e-04	169	147	5	b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZEB2 FCRL6 JAG2 PLAAT3 KLRC1	2.45e-04	169	147	5	e7470a5b060881b2a8ce2ab04b0788396aa13889
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_naive\|bone_marrow / Manually curated celltypes from each tissue	ZNF793 SOBP PEG10 FCGBP ZNF283	2.58e-04	171	147	5	fcc31a9a69f96de10d1324a5a4fbfe4289bf4984
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR7 ZEB2 ADAM22 JAG2 IL17RD	2.66e-04	172	147	5	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	INSR PRSS22 NRP2 FCGBP ZNF737	2.66e-04	172	147	5	63a91974b12c3f7f0c6bf66c30088d7fc07f5cea
ToppCell	390C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF793 SOBP EDNRB JAG2 OSGIN2	2.66e-04	172	147	5	84d16cd7f618c94888920680bdc9e7130d73fd75
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PARP14 ZEB2 PRDM2 UVRAG ALOX5	2.73e-04	173	147	5	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE NEDD4 LRRC42 SLC45A2 FGR	2.73e-04	173	147	5	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	normal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	ZEB2 FCRL6 PLAAT3 NOMO2 FGR	2.73e-04	173	147	5	1e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCell	NS-control-d_0-4-Myeloid-Monocyte-derived_Macrophage\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FLT3 CALHM6 ZEB2 CLIC2 FGR	2.80e-04	174	147	5	758984730cd1c3ccf6866a3a8f03d6e002f3edb6
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	INSR FER1L6 FCGBP ASXL3 CDON	2.80e-04	174	147	5	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAT CPOX SLC25A51 PLAAT3 S100A7A	2.95e-04	176	147	5	fc51e4dcad5456c229d76fdcb9a80c4c79eacf3f
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAJC13 GNE PRSS22 ADAM22 FCGBP	3.03e-04	177	147	5	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	INSR PRSS22 MBD3L4 FER1L6 FCGBP	3.03e-04	177	147	5	779ba86f53650772755b52460be03f18bb204e55
Disease	Lung diseases	PCSK5 CRISPLD2 INSR ACE IGF2R	3.46e-05	78	139	5	C0024115
Disease	S-warfarin measurement	CRISPLD2 MAGEL2 ADAM7 ZNF534 FGR	9.82e-05	97	139	5	EFO_0803323
Disease	cortical surface area measurement, neuroimaging measurement	EFCAB5 ADAMTS19 VRK2 SKIDA1 JAG2 ENO4 AGBL1	1.05e-04	227	139	7	EFO_0004346, EFO_0010736
Disease	Acidosis, Lactic	DNM1L PLAT	3.26e-04	6	139	2	C0001125
Disease	aortic valve disease (implicated_via_orthology)	ADAMTS19 RBPJ	3.26e-04	6	139	2	DOID:62 (implicated_via_orthology)
Disease	pulmonary fibrosis (is_marker_for)	DNM1L CAT ALOX5	4.59e-04	32	139	3	DOID:3770 (is_marker_for)
Disease	Malignant neoplasm of breast	MAGEA1 ADAMTS19 PHF7 CAT CFHR5 NDUFA8 ECT2 SLC25A51 ZEB2 EDNRB NEDD4 JAG2 OTOGL PLS3	5.66e-04	1074	139	14	C0006142
Disease	Pulmonary Hypertension	ACE EDNRB ALOX5	8.90e-04	40	139	3	C0020542
Disease	systolic blood pressure, self reported educational attainment	CADPS CDON	9.67e-04	10	139	2	EFO_0004784, EFO_0006335
Disease	osteonecrosis (is_implicated_in)	CAT PLAT	9.67e-04	10	139	2	DOID:10159 (is_implicated_in)
Disease	sexual dysfunction	ADAMTS19 PRKD1	1.18e-03	11	139	2	EFO_0004714
Disease	Hirschsprung's disease (is_implicated_in)	ZEB2 EDNRB	1.18e-03	11	139	2	DOID:10487 (is_implicated_in)
Disease	brain measurement, neuroimaging measurement	ADAMTS19 VRK2 SKIDA1 BEND3 JAG2 ZNF462 NEO1 CADPS AGBL1	1.23e-03	550	139	9	EFO_0004346, EFO_0004464
Disease	type 2 diabetes mellitus (is_implicated_in)	MAPK8IP1 INSR ACE IGF2R PLAT	1.33e-03	171	139	5	DOID:9352 (is_implicated_in)
Disease	total blood protein measurement	ZCCHC24 FLT3 DNAJC13 RGS12 KAT7 RBPJ TMEM131L ASCC3	1.34e-03	449	139	8	EFO_0004536
Disease	Pulmonary Thromboembolisms	CAT PLAT	1.41e-03	12	139	2	C0524702
Disease	Pulmonary Embolism	CAT PLAT	1.41e-03	12	139	2	C0034065
Disease	lung disease (implicated_via_orthology)	CAT ACE	1.66e-03	13	139	2	DOID:850 (implicated_via_orthology)
Disease	neuroimaging measurement	VRK2 SKIDA1 BEND3 CHD7 NDUFA8 NRP2 JAG2 ZNF462 ENO4 NEO1 CADPS AGBL1 GABBR1	1.67e-03	1069	139	13	EFO_0004346
Disease	cortical surface area measurement	EFCAB5 ADAMTS19 VRK2 DNAJC13 FAM178B SKIDA1 BEND3 CHD7 JAG2 NEO1 CADPS PRKD1 IL17RD AGBL1 CTSO	1.73e-03	1345	139	15	EFO_0010736
Disease	granulocyte percentage of myeloid white cells	FLT3 MAML1 BEND3 CHD7 DPP8 KLRC1	1.74e-03	268	139	6	EFO_0007997
Disease	Congestive heart failure	CAT ACE EDNRB PLAT	1.85e-03	110	139	4	C0018802
Disease	Heart failure	CAT ACE EDNRB PLAT	1.85e-03	110	139	4	C0018801
Disease	Left-Sided Heart Failure	CAT ACE EDNRB PLAT	1.85e-03	110	139	4	C0023212
Disease	Heart Failure, Right-Sided	CAT ACE EDNRB PLAT	1.85e-03	110	139	4	C0235527
Disease	Heart Decompensation	CAT ACE EDNRB PLAT	1.85e-03	110	139	4	C1961112
Disease	Myocardial Failure	CAT ACE EDNRB PLAT	1.85e-03	110	139	4	C1959583
Disease	Diabetic Neuralgia	INSR CAT	1.93e-03	14	139	2	C0751074
Disease	Diabetic Neuropathies	INSR CAT	1.93e-03	14	139	2	C0011882
Disease	Asymmetric Diabetic Proximal Motor Neuropathy	INSR CAT	1.93e-03	14	139	2	C0271674
Disease	Symmetric Diabetic Proximal Motor Neuropathy	INSR CAT	1.93e-03	14	139	2	C0271673
Disease	Diabetic Mononeuropathy	INSR CAT	1.93e-03	14	139	2	C0271678
Disease	Diabetic Autonomic Neuropathy	INSR CAT	1.93e-03	14	139	2	C0271686
Disease	Diabetic Amyotrophy	INSR CAT	1.93e-03	14	139	2	C0271685
Disease	Diabetic Polyneuropathies	INSR CAT	1.93e-03	14	139	2	C0271680
Disease	Diabetic Asymmetric Polyneuropathy	INSR CAT	1.93e-03	14	139	2	C0393835
Disease	Hypotension	CAT ACE PLAT	2.02e-03	53	139	3	C0020649
Disease	FEV/FEC ratio	PCSK5 EFCAB5 SKIDA1 ANKS1B ZFAND5 ZEB2 FAM83B NRP2 KAT7 FCGBP CADPS MRC2 LTBP3 CDON	2.02e-03	1228	139	14	EFO_0004713
Disease	Drug habituation	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C0013170
Disease	Drug abuse	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C0013146
Disease	Prescription Drug Abuse	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C4316881
Disease	Substance-Related Disorders	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C0236969
Disease	Drug Use Disorders	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C0013222
Disease	Drug Dependence	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C1510472
Disease	Substance Dependence	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C0038580
Disease	Substance Use Disorders	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	INSR TIAM2 PACS1 SLC45A2	2.18e-03	115	139	4	C0029231
Disease	amyotrophic lateral sclerosis, age at onset	PCSK5 ANKS1B	2.22e-03	15	139	2	EFO_0004847, MONDO_0004976
Disease	Substance abuse problem	INSR TIAM2 PACS1 SLC45A2	2.25e-03	116	139	4	C0740858
Disease	Prostatic Neoplasms	ZFAND5 CHD7 ACE IVNS1ABP IGF2R THYN1 IL17RD ALOX5 NOL8	2.64e-03	616	139	9	C0033578
Disease	Malignant neoplasm of prostate	ZFAND5 CHD7 ACE IVNS1ABP IGF2R THYN1 IL17RD ALOX5 NOL8	2.64e-03	616	139	9	C0376358
Disease	Brain Ischemia	CAT ACE PLAT	2.88e-03	60	139	3	C0007786
Disease	Cerebral Ischemia	CAT ACE PLAT	2.88e-03	60	139	3	C0917798
Disease	Idiopathic hypogonadotropic hypogonadism	CHD7 IL17RD	3.21e-03	18	139	2	C0342384
Disease	Congenital hernia of foramen of Morgagni	INSR IGF2R	3.57e-03	19	139	2	C0265699
Disease	portal hypertension (implicated_via_orthology)	EDNRB ALOX5	3.57e-03	19	139	2	DOID:10762 (implicated_via_orthology)
Disease	Congenital hernia of foramen of Bochdalek	INSR IGF2R	3.57e-03	19	139	2	C0265700
Disease	inflammatory bowel disease (is_implicated_in)	IL37 ANO6	3.57e-03	19	139	2	DOID:0050589 (is_implicated_in)
Disease	Pancreatic carcinoma	RBBP8 ALOX5	3.57e-03	19	139	2	C0235974
Disease	ankylosing spondylitis (is_implicated_in)	ACE ANO6	3.57e-03	19	139	2	DOID:7147 (is_implicated_in)
Disease	comparative body size at age 10, self-reported	FLT3 ANKS1B ZNF462 TNNI3K CADPS PRKD1 ZC3HAV1	3.85e-03	420	139	7	EFO_0009819
Disease	unipolar depression, bipolar disorder, schizophrenia	PCSK5 ADAMTS19	3.96e-03	20	139	2	EFO_0003761, MONDO_0004985, MONDO_0005090
Disease	Congenital diaphragmatic hernia	INSR IGF2R	4.36e-03	21	139	2	C0235833

Protein segments in the cluster

Peptide	Gene	Start	Entry
QKPDFHCLEYFKSFN	C4orf33	161	Q8N1A6
ELYHCLEGNHKKQPF	RBBP8	281	Q99708
KLVNANGEAVYCKFH	CAT	221	P04040
LAYINTKHPDFADAC	DNM1L	491	O00429
PLHKCDIYQSKEAGQ	ACE	1151	P12821
PYNFHDFQFCGNKKL	ADAM7	396	Q9H2U9
PKKFTQCNIEEYHDF	ADAM22	411	Q9P0K1
CNTYFPHNDDAKTGI	ADAM22	711	Q9P0K1
AFYLCGRKPDHKNGQ	GIT2	231	Q14161
EKQSCLKFKANDHGY	EDNRB	416	P24530
NCKYHLGEETFKLAQ	APPBP2	176	Q92624
DYFQKGGLQIKFHCS	FAM186B	446	Q8IYM0
CNPDALFQEDSYKKH	CHD7	1716	Q9P2D1
QEKFHDLAYSCLGKS	MIR9-1HG	101	Q13536
QSCPKAIKTEHANYL	ASXL3	1636	Q9C0F0
PAAASSKQHCYSKDQ	AGBL1	386	Q96MI9
DFQGNDKTYHCKDLP	KLRC1	51	P26715
CVYLKGLPFEAENKH	RBM12	431	Q9NTZ6
LNFSKNSEGKYHCPV	PPIL2	91	Q13356
KHGTLKYQTDCAPNN	NOMO3	61	P69849
RHGNECFSSEKPAAY	ADAMTS19	1121	Q8TE59
FHAFLKINQAKPECG	ECT2	571	Q9H8V3
DKNCSKIHFISPNIY	PSMB7	71	Q99436
FGLCAKPKGNKDYHL	MELK	151	Q14680
YNHSGACNKKQLDPT	BEND3	761	Q5T5X7
VNSGIYKAAFPLHDC	ANO6	236	Q4KMQ2
NPFHLYGKREQCEKG	ANKS1B	621	Q7Z6G8
HPEKLIFQSCDYKAF	ANKS1B	1051	Q7Z6G8
DYNLCNGKFHKHLQD	CADPS	961	Q9ULU8
DYGNTKPLSHYKADC	MAML1	511	Q92585
KHGTLKYQTDCAPNN	NOMO2	61	Q5JPE7
NTGCHLIGYFSKEKN	KAT7	451	O95251
GLNYHKRCAFKIPNN	PRKD1	181	Q15139
PKVFLCYSSKDGQNH	IL17RD	356	Q8NFM7
SVIKNYKHCFPEIFG	MAGEA1	131	P43355
YKHCFPEIFGKASES	MAGEA1	136	P43355
YKNHFPDIFSKASEC	MAGEA8	146	P43361
CAFGYQLKEIDTKNH	MAGEL2	1071	Q9UJ55
IYCKPHFNQLFKSKG	LIMA1	436	Q9UHB6
PNSGLCNEDHLSYFK	NEDD4	1041	P46934
LIKDDEYNPCQGSKF	FGR	406	P09769
SDPYGQKGLKNCDVF	IVNS1ABP	471	Q9Y6Y0
DCSHYKKLPPGQQRF	SPINK9	31	Q5DT21
LKNISFCGYHPKNNK	MAPK8IP1	641	Q9UQF2
HDSKCDPGQATKYLY	GABBR1	216	Q9UBS5
PGGHKDVLYQCKNFT	JAG2	1141	Q9Y219
NIIDLTNKDPCYSKH	LCN9	151	Q8WX39
ITAAHCFKDNLNKPY	PRSS22	86	Q9GZN4
FYLDEKIVGNHSAPC	FCRL6	241	Q6DN72
NDECKSDNYIEPHYK	FAM83B	11	Q5T0W9
YHQPDDKKKNRGFCF	SYNCRIP	276	O60506
KGDEHLEKPQQLCAY	MBD3L5	76	A6NJ08
PDYNVKFSLGNHCTE	FAM135A	811	Q9P2D6
KGYFIAPTNHTCQKL	PCSK5	1006	Q92824
ENCNYAVELGKHPAK	PLS3	461	P13797
YQCPAGCLNHKAKIF	CRISPLD2	306	Q9H0B8
KGDEHLEKPQQLCAY	MBD3L2B	76	A0A1B0GVZ6
NFNPHFEIEKHDCKY	NRP2	71	O60462
KHGTLKYQTDCAPNN	NOMO1	61	Q15155
GGHYADNCPAKASKS	PEG10	301	Q86TG7
NSHGKPCTIPFKYDN	MRC2	181	Q9UBG0
EKLQFYKEKAPDCHG	LRRC42	361	Q9Y546
GKLFFHYNPKLCLSE	INSR	451	P06213
YCHNLKKIGEDFSNT	NOL8	171	Q76FK4
KGDEHLEKPQQLCAY	MBD3L3	76	A6NE82
TCRHKFPDEDSYQKF	PACS1	731	Q6VY07
QHLCLKGPSADVYKA	PARP14	506	Q460N5
FLKDQGCYLGHKSSQ	OSGIN2	421	Q9Y236
GLDNGYSISKFCNHK	FLT3	396	P36888
YSISKFCNHKHQPGE	FLT3	401	P36888
FFQNPDFKLGSHCKQ	EFCAB5	316	A4FU69
EKCPNLTHLYLSGNK	ANP32C	81	O43423
YKDFCEHGTKSGLNQ	HECTD1	1951	Q9ULT8
YCDKDKGQSHPSLQL	IL37	121	Q9NZH6
SKHDNRTSFDKGPYC	C3orf84	56	H3BNL1
ALHLQFGKQYPCSKI	GNE	346	Q9Y223
NIKCFFEGSHPKEYN	CALHM6	236	Q5R3K3
LCGNYNGDPKDDFQK	FCGBP	3791	Q9Y6R7
NCSGKYFAFKEQLKH	CFAP70	561	Q5T0N1
CDFFISKYSNQKNPH	DPP8	581	Q6V1X1
KGSYKCAAYNPVTHQ	CDON	186	Q4KMG0
CLLHKGYKSSPDQFV	ACSL5	121	Q9ULC5
AKTGDAVEFQCKFPH	CFHR5	531	Q9BXR6
KYNPGSESECIGHFK	DNAJC13	1761	O75165
EQPHHKKECYLNFDD	LTBP3	911	Q9NS15
VYGHLANCFSKLAKP	ENO4	51	A6NNW6
TSQLDHAKEKNGGCY	SLC15A5	281	A6NIM6
PNFLSACDKKGIHYL	S100A7A	41	Q86SG5
GPIKAYLFDVCSHQD	SLC45A2	161	Q9UMX9
KEACDQHGPDLYPKF	CPOX	301	P36551
KAAAHHYGAQCDKPN	NDUFA8	26	P51970
YSHGIELACQKQKEF	CDC37L1	46	Q7L3B6
HLSPKYKESFDVGCN	CLIC2	101	O15247
KGDEHLEKPQQLCAY	MBD3L4	76	A6NDZ8
YIGSLNKHAAFSCPK	PRDM2	1466	Q13029
PCEAHQNKFPYAKKE	OTOGL	1121	Q3ZCN5
KGDEHLEKPQQLCAY	MBD3L2	76	Q8NHZ7
HSYQKPQSFGQDCKS	PHF20L1	861	A8MW92
GQRDKVFPHNESKYC	RP1	796	P56715
TKLCKDNKLDGPYFH	FER1L6	1481	Q2WGJ9
VCNDDVYSGPLKFLH	IGF2R	1041	P11717
HNYGRFEKKCNPAFL	SPATA48	51	A4D263
HKDYFVCGVKLPNSE	UVRAG	336	Q9P2Y5
VNNKHDDKYSPLPCS	PLAAT3	76	P53816
DVISPHSYKSNCKNF	TMEM131L	921	A2VDJ0
GCSEKHLLDKPFYND	ALOX5	31	P09917
EYKSFCDKHRPTQNI	PHF7	136	Q9BWX1
NTYQAFKALKCHGIG	SLC25A51	156	Q9H1U9
GCSPFLDHDVDYQKL	TDRD12	21	Q587J7
QQPKASAELDHKACY	FAM178B	581	Q8IXR5
HSKHNKPDEGYYQCV	NEO1	116	Q92859
NSEKYSKILHCPEFA	SKIDA1	631	Q1XH10
FCAEIKSPKYGEGHQ	SEPHS1	336	P49903
GHCKQLEPVYNSLAK	PDIA4	556	P13667
NTYQAFKALKCHGIG	SLC25A52	156	Q3SY17
HSDDKCEPKYFVFNS	SLC38A4	316	Q969I6
LACHPNLDKLGYSQK	CYB5R1	286	Q9UHQ9
CHILAAAYKFKSDQG	SMARCC2	91	Q8TAQ2
KDSEYPFKAQNGLCH	CTSO	191	P43234
YKKFLNEHLQEACTP	ASCC3	196	Q8N3C0
PYKCEEHGKVFNQSS	ZNF107	551	Q9UII5
ECGKAFYQKPNLSRH	ZNF793	371	Q6ZN11
NKYDNGCAKLFFHTE	ZNF182	181	P17025
LGKHNYCRNPDGDAK	PLAT	261	P00750
KECGKTFSLHGYLNQ	ZNF573	501	Q86YE8
SDKHNCPYDYKAEAA	ZFAND5	181	O76080
EKQSNEFGKPFYHCA	ZNF568	201	Q3ZCX4
QACEYFNHVPAHDKK	RGS12	746	O14924
HPKKENVFCLSNSFG	TIAM2	581	Q8IVF5
HYAKETPRLAFKNNC	SOBP	206	A7XYQ1
GFQEKEAFTKTPCYH	RNF25	141	Q96BH1
YCILDGHQEKIGNFK	TOP1MT	176	Q969P6
KPYNNKECGKVFSHH	ZNF534	281	Q76KX8
YHFFCAKKDDAVPQS	PHF11	131	Q9UIL8
ADDPVSQLHKCAFYL	RBPJ	276	Q06330
KFGEHNECTDALYQK	ZNF658	351	Q5TYW1
KSYKCPDNDNSLTHG	ZNF10	236	P21506
KLGEEAFFYHSNCKE	THYN1	106	Q9P016
NEQKPVHFGKSQYEC	ZNF544	286	Q6NX49
EYKECGKAFNQSSHL	ZNF681	311	Q96N22
NHKSIHFGDKPYKCD	ZFP62	326	Q8NB50
HKHSFCDNLPKFEGQ	ZNF462	621	Q96JM2
AKDAIYSHKNCPYDA	ZC3HAV1	821	Q7Z2W4
PECFSAFGNRKNLKH	THAP3	61	Q8WTV1
KYRHEKNEENFSCPL	ZEB2	231	O60315
KECDNFYHNFTKIPT	PRSS50	271	Q9UI38
DTPLHLACYNGKFEV	TNNI3K	271	Q59H18
YNQPACKLSHGKTEV	WDR7	851	Q9Y4E6
FLVCAHSLAYDEKPN	VRK2	291	Q86Y07
KECGKDFRYPTHLNN	ZNF560	351	Q96MR9
RAHEFKSQGAQCYKD	TTC9	56	Q92623
RTHSNDKPYKYNECG	ZNF283	646	Q8N7M2
LCFNKGHYIKDCPQA	ZCCHC24	136	Q8N2G6
YGHDNLQFKKGCESV	ZNF737	106	O75373