Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-tocopherol omega-hydroxylase activity	CYP4F3 CYP4F12 CYP4F11	8.22e-07	5	88	3	GO:0052871
GeneOntologyMolecularFunction	leukotriene-B4 20-monooxygenase activity	CYP4F3 CYP4F12 CYP4F11	2.86e-06	7	88	3	GO:0050051
GeneOntologyMolecularFunction	alkane 1-monooxygenase activity	CYP4F3 CYP4F12 CYP4F11	2.86e-06	7	88	3	GO:0018685
GeneOntologyMolecularFunction	arachidonate omega-hydroxylase activity	CYP4F3 CYP4F12 CYP4F11	9.71e-06	10	88	3	GO:0052869
GeneOntologyMolecularFunction	fatty acid omega-hydroxylase activity	CYP4F3 CYP4F12 CYP4F11	9.71e-06	10	88	3	GO:0120250
GeneOntologyMolecularFunction	long-chain fatty acid omega-hydroxylase activity	CYP4F3 CYP4F12 CYP4F11	9.71e-06	10	88	3	GO:0102033
GeneOntologyMolecularFunction	complement component C3b receptor activity	CR1 CR1L	1.92e-05	2	88	2	GO:0004877
GeneOntologyMolecularFunction	complement component C4b receptor activity	CR1 CR1L	1.92e-05	2	88	2	GO:0001861
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	CYP4F3 CYP4F12 CYP4F11	2.29e-05	13	88	3	GO:0016713
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	MICAL2 CYP4F3 CYP4F12 CYP4F11	2.85e-05	40	88	4	GO:0016709
GeneOntologyMolecularFunction	complement component C4b binding	CR1 CR1L	5.74e-05	3	88	2	GO:0001855
GeneOntologyMolecularFunction	arachidonate epoxygenase activity	CYP4F3 CYP4F12 CYP4F11	1.57e-04	24	88	3	GO:0008392
GeneOntologyMolecularFunction	extracellular matrix structural constituent	VWF COL15A1 LAMA5 PAPLN NTN1 SSPOP	1.84e-04	188	88	6	GO:0005201
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP4F3 CYP4F12 CYP4F11	2.24e-04	27	88	3	GO:0008391
GeneOntologyMolecularFunction	aromatase activity	CYP4F3 CYP4F12 CYP4F11	4.89e-04	35	88	3	GO:0070330
GeneOntologyMolecularFunction	nodal binding	CFC1 CFC1B	5.28e-04	8	88	2	GO:0038100
GeneOntologyMolecularFunction	opsonin receptor activity	CR1 CR1L	5.28e-04	8	88	2	GO:0001847
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXND1 PLXNB1	1.23e-03	12	88	2	GO:0017154
GeneOntologyMolecularFunction	complement component C3b binding	CR1 CR1L	1.23e-03	12	88	2	GO:0001851
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	CYP4F3 CYP4F12 CYP4F11	1.32e-03	49	88	3	GO:0016712
GeneOntologyMolecularFunction	cysteine-type peptidase activity	SFRP1 USP42 USP29 CAPN5 TNFAIP3	1.60e-03	192	88	5	GO:0008234
GeneOntologyMolecularFunction	monooxygenase activity	MICAL2 CYP4F3 CYP4F12 CYP4F11	1.68e-03	115	88	4	GO:0004497
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	MICAL2 POR CYP4F3 CYP4F12 CYP4F11	1.68e-03	194	88	5	GO:0016705
GeneOntologyMolecularFunction	complement receptor activity	CR1 CR1L	1.69e-03	14	88	2	GO:0004875
GeneOntologyMolecularFunction	activin receptor binding	CFC1 CFC1B	1.69e-03	14	88	2	GO:0070697
GeneOntologyMolecularFunction	arachidonate binding	CYP4F12 CYP4F11	1.94e-03	15	88	2	GO:0050544
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EFNB3 EPHA10	1.94e-03	15	88	2	GO:0005005
GeneOntologyMolecularFunction	icosanoid binding	CYP4F12 CYP4F11	2.21e-03	16	88	2	GO:0050542
GeneOntologyMolecularFunction	icosatetraenoic acid binding	CYP4F12 CYP4F11	2.21e-03	16	88	2	GO:0050543
GeneOntologyMolecularFunction	peptidase activity	SFRP1 ADAMTS7 USP42 ADAMTS9 ADAM23 USP29 ELANE CAPN5 TNFAIP3	2.34e-03	654	88	9	GO:0008233
GeneOntologyMolecularFunction	endopeptidase activity	SFRP1 ADAMTS7 ADAMTS9 ADAM23 USP29 ELANE CAPN5	2.90e-03	430	88	7	GO:0004175
GeneOntologyMolecularFunction	ephrin receptor activity	EFNB3 EPHA10	3.13e-03	19	88	2	GO:0005003
GeneOntologyMolecularFunction	histone modifying activity	GTF2B KMT2D HDAC8 NSD1 TRIM37	3.44e-03	229	88	5	GO:0140993
GeneOntologyMolecularFunction	nuclear retinoid X receptor binding	UIMC1 NSD1	4.57e-03	23	88	2	GO:0046965
GeneOntologyBiologicalProcess	leukotriene B4 catabolic process	CYP4F3 CYP4F12 CYP4F11	1.49e-06	6	88	3	GO:0036101
GeneOntologyBiologicalProcess	leukotriene B4 metabolic process	CYP4F3 CYP4F12 CYP4F11	2.59e-06	7	88	3	GO:0036102
GeneOntologyBiologicalProcess	leukotriene catabolic process	CYP4F3 CYP4F12 CYP4F11	4.14e-06	8	88	3	GO:0036100
GeneOntologyBiologicalProcess	icosanoid catabolic process	CYP4F3 CYP4F12 CYP4F11	1.21e-05	11	88	3	GO:1901523
GeneOntologyBiologicalProcess	long-chain fatty acid catabolic process	CYP4F3 CYP4F12 CYP4F11	1.61e-05	12	88	3	GO:0042758
GeneOntologyBiologicalProcess	menaquinone catabolic process	CYP4F12 CYP4F11	5.38e-05	3	88	2	GO:0042361
GeneOntologyBiologicalProcess	menaquinone metabolic process	CYP4F12 CYP4F11	1.07e-04	4	88	2	GO:0009233
GeneOntologyBiologicalProcess	phylloquinone metabolic process	CYP4F12 CYP4F11	1.07e-04	4	88	2	GO:0042374
GeneOntologyBiologicalProcess	phylloquinone catabolic process	CYP4F12 CYP4F11	1.07e-04	4	88	2	GO:0042376
GeneOntologyBiologicalProcess	vitamin K catabolic process	CYP4F12 CYP4F11	1.07e-04	4	88	2	GO:0042377
GeneOntologyBiologicalProcess	left lung morphogenesis	CFC1 CFC1B	1.07e-04	4	88	2	GO:0060460
GeneOntologyBiologicalProcess	fatty acid derivative catabolic process	CYP4F3 CYP4F12 CYP4F11	1.09e-04	22	88	3	GO:1901569
GeneOntologyBiologicalProcess	gland development	CDKN2B GJA1 SFRP1 VWF CFC1 LAMA5 NTN1 CFC1B TNFAIP3 PLXND1	1.32e-04	558	88	10	GO:0048732
GeneOntologyBiologicalProcess	left lung development	CFC1 CFC1B	1.78e-04	5	88	2	GO:0060459
GeneOntologyBiologicalProcess	positive regulation of leukocyte adhesion to vascular endothelial cell	IRAK1 ELANE GP1BA	2.53e-04	29	88	3	GO:1904996
GeneOntologyBiologicalProcess	prostaglandin catabolic process	CYP4F12 CYP4F11	2.67e-04	6	88	2	GO:1905344
GeneOntologyBiologicalProcess	prostanoid catabolic process	CYP4F12 CYP4F11	2.67e-04	6	88	2	GO:0062232
GeneOntologyBiologicalProcess	heart looping	GJA1 MICAL2 CFC1 CFC1B	2.69e-04	73	88	4	GO:0001947
GeneOntologyBiologicalProcess	gastrulation	GJA1 SFRP1 CFC1 NSD1 CFC1B TNFAIP3	2.95e-04	212	88	6	GO:0007369
GeneOntologyBiologicalProcess	embryo development	GJA1 GTF2B KMT2D SFRP1 LMX1B MICAL2 CFC1 APBA2 NSD1 LAMA5 NTN1 CFC1B TNFAIP3 CR1 CR1L NCAPG2	3.44e-04	1437	88	16	GO:0009790
GeneOntologyBiologicalProcess	determination of heart left/right asymmetry	GJA1 MICAL2 CFC1 CFC1B	3.64e-04	79	88	4	GO:0061371
GeneOntologyBiologicalProcess	embryonic heart tube morphogenesis	GJA1 MICAL2 CFC1 CFC1B	3.82e-04	80	88	4	GO:0003143
GeneOntologyBiologicalProcess	positive regulation of leukocyte cell-cell adhesion	ZNF609 EFNB3 RASAL3 IRAK1 ELANE CR1 GP1BA	4.15e-04	317	88	7	GO:1903039
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	GJA1 SFRP1 MICAL2 CFC1 LAMA5 NTN1 CFC1B PLXND1	4.36e-04	421	88	8	GO:0060562
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	CR1 CR1L	4.96e-04	8	88	2	GO:0045959
GeneOntologyBiologicalProcess	aggresome assembly	DLGAP1 TRIM37	4.96e-04	8	88	2	GO:0070842
GeneOntologyBiologicalProcess	regulation of cell adhesion	ZNF609 SFRP1 EFNB3 RASAL3 IRAK1 LAMA5 ELANE TNFAIP3 PLXND1 CR1 PLXNB1 GP1BA	5.59e-04	927	88	12	GO:0030155
GeneOntologyBiologicalProcess	negative regulation of B cell differentiation	SFRP1 CR1	6.35e-04	9	88	2	GO:0045578
GeneOntologyCellularComponent	extracellular matrix	SFRP1 VWF COL15A1 ADAMTS7 ADAMTS9 FGFBP3 LAMA5 ELANE PAPLN NTN1 SSPOP GP1BA	2.15e-05	656	89	12	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	SFRP1 VWF COL15A1 ADAMTS7 ADAMTS9 FGFBP3 LAMA5 ELANE PAPLN NTN1 SSPOP GP1BA	2.22e-05	658	89	12	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	SFRP1 VWF COL15A1 ADAMTS9 FGFBP3 LAMA5 ELANE PAPLN NTN1 SSPOP	8.52e-05	530	89	10	GO:0062023
MousePheno	total anomalous pulmonary venous connection, intracardiac	CFC1 CFC1B	2.62e-05	2	72	2	MP:0010443
MousePheno	vascular ring	CFC1 LAMA5 CFC1B PLXND1	3.00e-05	35	72	4	MP:0010466
MousePheno	abnormal right subclavian artery morphology	CFC1 LAMA5 CFC1B PLXND1	5.14e-05	40	72	4	MP:0010487
MousePheno	abnormal cardiac outflow tract development	GJA1 CFC1 LAMA5 POR CFC1B PLXND1	6.45e-05	134	72	6	MP:0006126
MousePheno	mesocardia	CFC1 LAMA5 CFC1B	1.40e-04	20	72	3	MP:0000650
MousePheno	unbalanced complete common atrioventricular canal	CFC1 CFC1B	1.56e-04	4	72	2	MP:0011673
MousePheno	total anomalous pulmonary venous connection	CFC1 CFC1B	1.56e-04	4	72	2	MP:0010441
MousePheno	abnormal subclavian artery morphology	CFC1 LAMA5 CFC1B PLXND1	1.94e-04	56	72	4	MP:0003395
MousePheno	common atrium	CFC1 CFC1B PLXND1	2.45e-04	24	72	3	MP:0010406
MousePheno	right aortic arch	CFC1 LAMA5 CFC1B PLXND1	2.54e-04	60	72	4	MP:0004158
MousePheno	complete atrioventricular septal defect	CFC1 CFC1B PLXND1	3.13e-04	26	72	3	MP:0010413
Domain	TSP_1	ADAMTS7 ADAMTS9 PAPLN THSD7B SSPOP	1.24e-05	63	89	5	PF00090
Domain	TSP1	ADAMTS7 ADAMTS9 PAPLN THSD7B SSPOP	1.45e-05	65	89	5	SM00209
Domain	TSP1_rpt	ADAMTS7 ADAMTS9 PAPLN THSD7B SSPOP	1.45e-05	65	89	5	IPR000884
Domain	TSP1	ADAMTS7 ADAMTS9 PAPLN THSD7B SSPOP	1.45e-05	65	89	5	PS50092
Domain	EGF_2	ADAM23 CFC1 LAMA5 NTN1 CFC1B VWCE SSPOP EPHA10	3.87e-05	265	89	8	PS01186
Domain	CFC	CFC1 CFC1B	6.72e-05	3	89	2	PF09443
Domain	Cryptic/Cripto_CFC-dom	CFC1 CFC1B	6.72e-05	3	89	2	IPR019011
Domain	VWC_out	VWF VWCE SSPOP	9.59e-05	19	89	3	SM00215
Domain	ADAM_spacer1	ADAMTS7 ADAMTS9 PAPLN	1.73e-04	23	89	3	IPR010294
Domain	ADAM_spacer1	ADAMTS7 ADAMTS9 PAPLN	1.73e-04	23	89	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS7 ADAMTS9 PAPLN	1.97e-04	24	89	3	IPR013273
Domain	EGF_1	ADAM23 CFC1 LAMA5 NTN1 CFC1B VWCE SSPOP	2.17e-04	255	89	7	PS00022
Domain	KIND_dom	FRMPD2 KNDC1	2.22e-04	5	89	2	IPR011019
Domain	KIND	FRMPD2 KNDC1	2.22e-04	5	89	2	SM00750
Domain	KIND	FRMPD2 KNDC1	2.22e-04	5	89	2	PS51377
Domain	EGF-like_CS	ADAM23 CFC1 LAMA5 NTN1 CFC1B VWCE EPHA10	2.49e-04	261	89	7	IPR013032
Domain	VWFC_1	VWF VWCE SSPOP	6.67e-04	36	89	3	PS01208
Domain	VWC	VWF VWCE SSPOP	7.82e-04	38	89	3	SM00214
Domain	VWFC_2	VWF VWCE SSPOP	7.82e-04	38	89	3	PS50184
Domain	Plexin_cytopl	PLXND1 PLXNB1	7.91e-04	9	89	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNB1	7.91e-04	9	89	2	IPR013548
Domain	Plexin	PLXND1 PLXNB1	7.91e-04	9	89	2	IPR031148
Domain	Peptidase_M12B_N	ADAMTS7 ADAMTS9 ADAM23	8.44e-04	39	89	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS7 ADAMTS9 ADAM23	8.44e-04	39	89	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS7 ADAMTS9 ADAM23	9.10e-04	40	89	3	PS00427
Domain	Reprolysin	ADAMTS7 ADAMTS9 ADAM23	9.10e-04	40	89	3	PF01421
Domain	ADAM_MEPRO	ADAMTS7 ADAMTS9 ADAM23	9.10e-04	40	89	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS7 ADAMTS9 ADAM23	9.10e-04	40	89	3	PS50214
Domain	Peptidase_M12B	ADAMTS7 ADAMTS9 ADAM23	9.10e-04	40	89	3	IPR001590
Domain	Disintegrin_dom	ADAMTS7 ADAMTS9 ADAM23	9.78e-04	41	89	3	IPR001762
Domain	VWF_dom	VWF VWCE SSPOP	1.05e-03	42	89	3	IPR001007
Domain	Galactose-bd-like	LAMA5 NTN1 SSPOP EPHA10	1.06e-03	94	89	4	IPR008979
Domain	Cyt_P450_E_grp-I	CYP4F3 CYP4F12 CYP4F11	1.28e-03	45	89	3	IPR002401
Domain	TIL	VWF SSPOP	1.44e-03	12	89	2	PF01826
Domain	C8	VWF SSPOP	1.44e-03	12	89	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF SSPOP	1.69e-03	13	89	2	IPR014853
Domain	C8	VWF SSPOP	1.69e-03	13	89	2	SM00832
Domain	Sushi	CR1 CR1L CSMD3	1.95e-03	52	89	3	PF00084
Domain	TIL_dom	VWF SSPOP	1.97e-03	14	89	2	IPR002919
Domain	Cyt_P450_CS	CYP4F3 CYP4F12 CYP4F11	2.06e-03	53	89	3	IPR017972
Domain	CCP	CR1 CR1L CSMD3	2.18e-03	54	89	3	SM00032
Domain	Bbox_C	TRIM67 TRIM37	2.26e-03	15	89	2	IPR003649
Domain	BBC	TRIM67 TRIM37	2.26e-03	15	89	2	SM00502
Domain	SUSHI	CR1 CR1L CSMD3	2.42e-03	56	89	3	PS50923
Domain	Sushi_SCR_CCP_dom	CR1 CR1L CSMD3	2.54e-03	57	89	3	IPR000436
Domain	CYTOCHROME_P450	CYP4F3 CYP4F12 CYP4F11	2.54e-03	57	89	3	PS00086
Domain	Post-SET_dom	KMT2D NSD1	2.58e-03	16	89	2	IPR003616
Domain	VWD	VWF SSPOP	2.58e-03	16	89	2	SM00216
Domain	PostSET	KMT2D NSD1	2.58e-03	16	89	2	SM00508
Domain	VWF_type-D	VWF SSPOP	2.58e-03	16	89	2	IPR001846
Domain	Laminin_N	LAMA5 NTN1	2.58e-03	16	89	2	IPR008211
Domain	LAMININ_NTER	LAMA5 NTN1	2.58e-03	16	89	2	PS51117
Domain	VWFD	VWF SSPOP	2.58e-03	16	89	2	PS51233
Domain	Laminin_N	LAMA5 NTN1	2.58e-03	16	89	2	PF00055
Domain	POST_SET	KMT2D NSD1	2.58e-03	16	89	2	PS50868
Domain	VWD	VWF SSPOP	2.58e-03	16	89	2	PF00094
Domain	LamNT	LAMA5 NTN1	2.58e-03	16	89	2	SM00136
Domain	-	CYP4F3 CYP4F12 CYP4F11	2.67e-03	58	89	3	1.10.630.10
Domain	p450	CYP4F3 CYP4F12 CYP4F11	2.67e-03	58	89	3	PF00067
Domain	C345C	SFRP1 NTN1	2.91e-03	17	89	2	SM00643
Domain	Cyt_P450	CYP4F3 CYP4F12 CYP4F11	2.94e-03	60	89	3	IPR001128
Domain	RasGAP_dom	RASAL3 PLXNB1	3.27e-03	18	89	2	IPR001936
Domain	CTCK_1	VWF SSPOP	3.27e-03	18	89	2	PS01185
Domain	PLAC	ADAMTS7 PAPLN	3.64e-03	19	89	2	PS50900
Domain	NTR	SFRP1 NTN1	3.64e-03	19	89	2	PF01759
Domain	PLAC	ADAMTS7 PAPLN	3.64e-03	19	89	2	IPR010909
Domain	Netrin_module_non-TIMP	SFRP1 NTN1	3.64e-03	19	89	2	IPR018933
Domain	LIM	PRICKLE4 LMX1B MICAL2	4.37e-03	69	89	3	PF00412
Domain	-	PRICKLE4 LMX1B MICAL2	4.55e-03	70	89	3	2.10.110.10
Domain	Znf_LIM	PRICKLE4 LMX1B MICAL2	4.73e-03	71	89	3	IPR001781
Domain	LIM_DOMAIN_1	PRICKLE4 LMX1B MICAL2	4.73e-03	71	89	3	PS00478
Domain	LIM_DOMAIN_2	PRICKLE4 LMX1B MICAL2	4.73e-03	71	89	3	PS50023
Domain	LIM	PRICKLE4 LMX1B MICAL2	4.73e-03	71	89	3	SM00132
Pathway	REACTOME_EICOSANOIDS	CYP4F3 CYP4F12 CYP4F11	2.19e-05	12	67	3	M27129
Pathway	REACTOME_EICOSANOIDS	CYP4F3 CYP4F12 CYP4F11	2.19e-05	12	67	3	MM14845
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS7 ADAMTS9 THSD7B SSPOP	3.38e-05	39	67	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS7 ADAMTS9 THSD7B SSPOP	3.38e-05	39	67	4	MM15165
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES	CYP4F3 CYP4F12 CYP4F11	3.60e-05	14	67	3	MM15842
Pathway	REACTOME_FATTY_ACIDS	CYP4F3 CYP4F12 CYP4F11	4.48e-05	15	67	3	M27126
Pathway	REACTOME_MISCELLANEOUS_SUBSTRATES	CYP4F3 CYP4F12 CYP4F11	7.96e-05	18	67	3	MM14843
Pathway	REACTOME_FATTY_ACIDS	CYP4F3 CYP4F12 CYP4F11	7.96e-05	18	67	3	MM14841
Pathway	WP_OXIDATION_BY_CYTOCHROME_P450	POR CYP4F3 CYP4F12 CYP4F11	2.11e-04	62	67	4	M39653
Pathway	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX	CYP4F3 CYP4F12 CYP4F11	2.19e-04	25	67	3	MM14858
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	POR CYP4F3 CYP4F12 CYP4F11	2.39e-04	64	67	4	M5650
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS7 ADAMTS9 THSD7B SSPOP	3.02e-04	68	67	4	M27303
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	LMX1B LAMA5 CR1 CR1L	3.96e-04	73	67	4	MM15906
Pathway	REACTOME_ENHANCED_BINDING_OF_GP1BA_VARIANT_TO_VWF_MULTIMER_COLLAGEN	VWF GP1BA	4.60e-04	7	67	2	M48265
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX	CYP4F3 CYP4F12 CYP4F11	5.06e-04	33	67	3	MM15918
Pathway	WP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX	CYP4F3 CYP4F12 CYP4F11	5.06e-04	33	67	3	MM15963
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL15A1 ADAMTS9 LAMA5 ELANE CAPN5	5.30e-04	140	67	5	M587
Pathway	REACTOME_DEFECTS_OF_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	VWF GP1BA	6.12e-04	8	67	2	M48236
Pathway	REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE	CYP4F12 CYP4F11	1.19e-03	11	67	2	MM14863
Pathway	REACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING	VWF GP1BA	1.42e-03	12	67	2	MM15093
Pathway	REACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING	VWF GP1BA	1.42e-03	12	67	2	M27352
Pathway	WP_MIR127_IN_MESENDODERM_DIFFERENTIATION	CFC1 CFC1B	1.42e-03	12	67	2	MM15910
Pathway	REACTOME_MISCELLANEOUS_SUBSTRATES	CYP4F3 CYP4F11	1.42e-03	12	67	2	M27128
Pathway	REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	VWF GP1BA	1.42e-03	12	67	2	MM15452
Pathway	REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS	POR CYP4F3 CYP4F12 CYP4F11	1.50e-03	104	67	4	M738
Pubmed	Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.	CYP4F3 CYP4F12 CYP4F11	6.92e-08	4	91	3	18065749
Pubmed	Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.	POR CYP4F12 CYP4F11	1.73e-07	5	91	3	22969154
Pubmed	The cytochrome P450 4 (CYP4) family.	CYP4F3 CYP4F12 CYP4F11	3.45e-07	6	91	3	9068972
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS7 ADAMTS9 PAPLN THSD7B SSPOP	1.64e-06	75	91	5	20637190
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	VWF COL15A1 LAMA5 ELANE PAPLN NTN1	5.33e-06	167	91	6	22159717
Pubmed	Functional identification of transcription control sequences of the mouse Crry gene.	CR1 CR1L	6.77e-06	2	91	2	8335915
Pubmed	Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils.	LAMA5 ELANE	6.77e-06	2	91	2	18178964
Pubmed	Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice.	VWF GP1BA	6.77e-06	2	91	2	23742235
Pubmed	Specific electrostatic interactions between charged amino acid residues regulate binding of von Willebrand factor to blood platelets.	VWF GP1BA	6.77e-06	2	91	2	28924049
Pubmed	Red blood cells mediate the onset of thrombosis in the ferric chloride murine model.	VWF GP1BA	6.77e-06	2	91	2	23343833
Pubmed	Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.	CR1 CR1L	6.77e-06	2	91	2	10779754
Pubmed	von Willebrand Factor and Platelet Glycoprotein Ib: A Thromboinflammatory Axis in Stroke.	VWF GP1BA	6.77e-06	2	91	2	31921147
Pubmed	Astrocyte-specific expression of a soluble form of the murine complement control protein Crry confers demyelination protection in the cuprizone model.	CR1 CR1L	6.77e-06	2	91	2	17674370
Pubmed	Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.	CR1 CR1L	6.77e-06	2	91	2	16444293
Pubmed	Crystal structure of the platelet glycoprotein Ib(alpha) N-terminal domain reveals an unmasking mechanism for receptor activation.	VWF GP1BA	6.77e-06	2	91	2	12087105
Pubmed	Expression and physiological function of CYP4F subfamily in human eosinophils.	CYP4F3 CYP4F12	6.77e-06	2	91	2	17980168
Pubmed	Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl(3)-induced occlusive thrombus formation in the inferior vena cava of mice.	VWF GP1BA	6.77e-06	2	91	2	22720736
Pubmed	Force-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases.	VWF GP1BA	6.77e-06	2	91	2	25810255
Pubmed	Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals.	VWF GP1BA	6.77e-06	2	91	2	27434669
Pubmed	von Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activation.	VWF GP1BA	6.77e-06	2	91	2	20696943
Pubmed	Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.	CR1 CR1L	6.77e-06	2	91	2	1730912
Pubmed	Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.	CR1 CR1L	6.77e-06	2	91	2	19740350
Pubmed	Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice.	CR1 CR1L	6.77e-06	2	91	2	11698469
Pubmed	Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones.	CR1 CR1L	6.77e-06	2	91	2	34709768
Pubmed	The murine complement regulator Crry: new insights into the immunobiology of complement regulation.	CR1 CR1L	6.77e-06	2	91	2	11915940
Pubmed	Polyphosphate binds to human von Willebrand factor in vivo and modulates its interaction with glycoprotein Ib.	VWF GP1BA	6.77e-06	2	91	2	23006049
Pubmed	Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.	CR1 CR1L	6.77e-06	2	91	2	7691944
Pubmed	The murine complement receptor gene family. Analysis of mCRY gene products and their homology to human CR1.	CR1 CR1L	6.77e-06	2	91	2	2911011
Pubmed	O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions.	VWF GP1BA	6.77e-06	2	91	2	22517896
Pubmed	The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.	CFC1 CFC1B	6.77e-06	2	91	2	11174844
Pubmed	Flow-induced elongation of von Willebrand factor precedes tension-dependent activation.	VWF GP1BA	6.77e-06	2	91	2	28831047
Pubmed	Mutant botrocetin-2 inhibits von Willebrand factor-induced platelet agglutination.	VWF GP1BA	6.77e-06	2	91	2	28071872
Pubmed	Point mutation in a leucine-rich repeat of platelet glycoprotein Ib alpha resulting in the Bernard-Soulier syndrome.	VWF GP1BA	6.77e-06	2	91	2	7690774
Pubmed	A mechanism for localized dynamics-driven affinity regulation of the binding of von Willebrand factor to platelet glycoprotein Ibα.	VWF GP1BA	6.77e-06	2	91	2	23902764
Pubmed	Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations.	VWF GP1BA	6.77e-06	2	91	2	15039442
Pubmed	Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor.	VWF GP1BA	6.77e-06	2	91	2	6336654
Pubmed	Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.	CR1 CR1L	6.77e-06	2	91	2	12902517
Pubmed	Cutting edge: treatment of complement regulatory protein deficiency by retroviral in vivo gene therapy.	CR1 CR1L	6.77e-06	2	91	2	17015675
Pubmed	Sotos syndrome, infantile hypercalcemia, and nephrocalcinosis: a contiguous gene syndrome.	SLC34A1 NSD1	6.77e-06	2	91	2	21597970
Pubmed	von Willebrand factor variant D1472H has no effect in mice with humanized VWF-platelet interactions.	VWF GP1BA	6.77e-06	2	91	2	32870970
Pubmed	The A/T1381 polymorphism in the A1-domain of von Willebrand factor influences the affinity of von Willebrand factor for platelet glycoprotein Ibalpha.	VWF GP1BA	6.77e-06	2	91	2	17598011
Pubmed	Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.	VWF GP1BA	6.77e-06	2	91	2	12183630
Pubmed	A mechanically stabilized receptor-ligand flex-bond important in the vasculature.	VWF GP1BA	6.77e-06	2	91	2	20725043
Pubmed	Dynamic platelet function on von Willebrand factor is different in preterm neonates and full-term neonates: changes in neonatal platelet function.	VWF GP1BA	6.77e-06	2	91	2	27416003
Pubmed	Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibalpha and platelet activation under shear stress.	VWF GP1BA	6.77e-06	2	91	2	20498367
Pubmed	Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.	CR1 CR1L	6.77e-06	2	91	2	23153828
Pubmed	Blocking von Willebrand factor for treatment of cutaneous inflammation.	VWF GP1BA	6.77e-06	2	91	2	23812299
Pubmed	Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor.	VWF GP1BA	6.77e-06	2	91	2	16774914
Pubmed	Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.	CYP4F3 CYP4F11	6.77e-06	2	91	2	15364545
Pubmed	Platelet GpIba binding to von Willebrand Factor under fluid shear:contributions of the D′D3-domain, A1-domain flanking peptide and O-linked glycans.	VWF GP1BA	6.77e-06	2	91	2	25341886
Pubmed	The glycoprotein Ibalpha-von Willebrand factor interaction induces platelet apoptosis.	VWF GP1BA	6.77e-06	2	91	2	19840363
Pubmed	The N-terminal flanking region of the A1 domain regulates the force-dependent binding of von Willebrand factor to platelet glycoprotein Ibα.	VWF GP1BA	6.77e-06	2	91	2	24062306
Pubmed	Expansion of the complement receptor gene family. Identification in the mouse of two new genes related to the CR1 and CR2 gene family.	CR1 CR1L	6.77e-06	2	91	2	2952719
Pubmed	Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism.	VWF GP1BA	6.77e-06	2	91	2	19726719
Pubmed	Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice.	CR1 CR1L	6.77e-06	2	91	2	12973023
Pubmed	Exploiting the kinetic interplay between GPIbα-VWF binding interfaces to regulate hemostasis and thrombosis.	VWF GP1BA	6.77e-06	2	91	2	25293780
Pubmed	Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.	CFC1 CFC1B	6.77e-06	2	91	2	11327798
Pubmed	Synergic effect of GPIBA and von Willebrand factor in pathogenesis of deep vein thrombosis.	VWF GP1BA	6.77e-06	2	91	2	31902309
Pubmed	Shear-induced interaction of platelets with von Willebrand factor results in glycoprotein Ibalpha shedding.	VWF GP1BA	6.77e-06	2	91	2	19820200
Pubmed	Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.	CFC1 CFC1B	6.77e-06	2	91	2	11024280
Pubmed	Regulation of gap junction function and Connexin 43 expression by cytochrome P450 oxidoreductase (CYPOR).	GJA1 POR	6.77e-06	2	91	2	21726529
Pubmed	Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis.	CR1 CR1L	6.77e-06	2	91	2	10586048
Pubmed	A G-quartet oligonucleotide blocks glycoprotein Ib-mediated platelet adhesion and aggregation under flow conditions.	VWF GP1BA	6.77e-06	2	91	2	19718474
Pubmed	Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val-481-Gly-718) to the N-terminal region of the alpha-chain of membrane glycoprotein Ib on intact platelets with bis(sulfosuccinimidyl) suberate.	VWF GP1BA	6.77e-06	2	91	2	2690940
Pubmed	In vivo correction of complement regulatory protein deficiency with an inhibitor targeting the red blood cell membrane.	CR1 CR1L	6.77e-06	2	91	2	16301687
Pubmed	Shielding of the A1 domain by the D'D3 domains of von Willebrand factor modulates its interaction with platelet glycoprotein Ib-IX-V.	VWF GP1BA	6.77e-06	2	91	2	16373331
Pubmed	Expression dynamics of Crry at the implantation sites in normal pregnancy and response against miscarriage induction.	CR1 CR1L	6.77e-06	2	91	2	36450590
Pubmed	Gain of von Willebrand factor-binding function by mutagenesis of a species-conserved residue within the leucine-rich repeat region of platelet glycoprotein Ibalpha.	VWF GP1BA	6.77e-06	2	91	2	15933060
Pubmed	Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts.	CR1 CR1L	6.77e-06	2	91	2	16301324
Pubmed	The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.	CR1 CR1L	6.77e-06	2	91	2	12767833
Pubmed	Recruitment of proteins to DNA double-strand breaks: MDC1 directly recruits RAP80.	UIMC1 MDC1	6.77e-06	2	91	2	21857162
Pubmed	GpIbα-VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice.	VWF GP1BA	6.77e-06	2	91	2	24553181
Pubmed	The murine complement receptor gene family. III. The genomic and transcriptional complexity of the Crry and Crry-ps genes.	CR1 CR1L	6.77e-06	2	91	2	2307848
Pubmed	Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.	CFC1 CFC1B	6.77e-06	2	91	2	11062482
Pubmed	Structural basis of regulation of von Willebrand factor binding to glycoprotein Ib.	VWF GP1BA	6.77e-06	2	91	2	24391089
Pubmed	The mucin-like macroglycopeptide region of glycoprotein Ibalpha is required for cell adhesion to immobilized von Willebrand factor (VWF) under flow but not for static VWF binding.	VWF GP1BA	6.77e-06	2	91	2	12362242
Pubmed	Site-directed mutagenesis of platelet glycoprotein Ib alpha demonstrating residues involved in the sulfation of tyrosines 276, 278, and 279.	VWF GP1BA	6.77e-06	2	91	2	12036871
Pubmed	Complement regulatory protein Crry/p65 costimulation expands natural treg cells with enhanced suppressive properties in proteoglycan-induced arthritis.	CR1 CR1L	6.77e-06	2	91	2	21380996
Pubmed	Regulation of complement activity via the alternative pathway in placentas of mouse spontaneous abortions.	CR1 CR1L	6.77e-06	2	91	2	20484840
Pubmed	Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.	GJA1 VWF LAMA5	9.47e-06	16	91	3	26953188
Pubmed	Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo.	GJA1 CFC1 CFC1B	1.15e-05	17	91	3	22627279
Pubmed	Reconstitution of adhesive properties of human platelets in liposomes carrying both recombinant glycoproteins Ia/IIa and Ib alpha under flow conditions: specific synergy of receptor-ligand interactions.	VWF GP1BA	2.03e-05	3	91	2	12070018
Pubmed	Duplication and divergence of the amino-terminal coding region of the complement receptor 1 (CR1) gene. An example of concerted (horizontal) evolution within a gene.	CR1 CR1L	2.03e-05	3	91	2	2295627
Pubmed	Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.	CFC1 CFC1B	2.03e-05	3	91	2	16835440
Pubmed	Platelet glycoprotein Ib-IX as a regulator of systemic inflammation.	VWF GP1BA	2.03e-05	3	91	2	24504734
Pubmed	Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury.	CR1 CR1L	2.03e-05	3	91	2	24850152
Pubmed	Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.	CR1 CR1L	2.03e-05	3	91	2	11907125
Pubmed	Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF.	VWF GP1BA	2.03e-05	3	91	2	18725999
Pubmed	Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.	CR1 CR1L	2.03e-05	3	91	2	2528587
Pubmed	Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.	CR1 CR1L	2.03e-05	3	91	2	7528766
Pubmed	An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.	CR1 CR1L	2.03e-05	3	91	2	20660348
Pubmed	Dissecting coronary angiogenesis: 3D co-culture of cardiomyocytes with endothelial or mesenchymal cells.	GJA1 VWF	2.03e-05	3	91	2	19769963
Pubmed	Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin binding.	VWF GP1BA	2.03e-05	3	91	2	7721887
Pubmed	Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13.	VWF GP1BA	2.03e-05	3	91	2	15249683
Pubmed	[Hepatitis B virus X protein upregulates the expression of CD59 and Crry in mouse podocytes].	CR1 CR1L	2.03e-05	3	91	2	21215189
Pubmed	Simultaneous exposure of sites in von Willebrand factor for glycoprotein Ib binding and ADAMTS13 cleavage: studies with ristocetin.	VWF GP1BA	2.03e-05	3	91	2	22922961
Pubmed	Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain.	FRMPD2 KNDC1	2.03e-05	3	91	2	21385318
Pubmed	The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.	CR1 CR1L	2.03e-05	3	91	2	2139460
Pubmed	A critical role for murine complement regulator crry in fetomaternal tolerance.	CR1 CR1L	2.03e-05	3	91	2	10642554
Pubmed	Platelet GPIbalpha, GPIV and vWF polymorphisms and fatal pre-hospital MI among middle-aged men.	VWF GP1BA	2.03e-05	3	91	2	17619827
Cytoband	8q24.3	THEM6 ZNF34 RECQL4 GPT DENND3	3.25e-06	113	91	5	8q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	THEM6 ZNF34 RECQL4 GPT DENND3	7.25e-04	355	91	5	chr8q24
Cytoband	5q35	SLC34A1 NSD1	9.57e-04	23	91	2	5q35
Cytoband	1q42.2	PCNX2 TRIM67	1.13e-03	25	91	2	1q42.2
Cytoband	9q21.11	FOXD4L3 FOXD4L6	1.63e-03	30	91	2	9q21.11
GeneFamily	Cytochrome P450 family 4	CYP4F3 CYP4F12 CYP4F11	2.53e-04	36	62	3	1003
GeneFamily	Plexins	PLXND1 PLXNB1	4.10e-04	9	62	2	683
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CR1 CR1L CSMD3	9.85e-04	57	62	3	1179
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS7 ADAMTS9	1.91e-03	19	62	2	50
Coexpression	NABA_MATRISOME	SFRP1 VWF COL15A1 ADAMTS7 ADAMTS9 ADAM23 FGFBP3 CFC1 LAMA5 ELANE PAPLN NTN1 CFC1B PLXND1 VWCE SSPOP PLXNB1	4.30e-08	1008	89	17	MM17056
Coexpression	NABA_MATRISOME	SFRP1 VWF COL15A1 ADAMTS7 ADAMTS9 ADAM23 FGFBP3 CFC1 LAMA5 ELANE PAPLN NTN1 CFC1B PLXND1 VWCE SSPOP PLXNB1	5.55e-08	1026	89	17	M5889
Coexpression	NABA_BASEMENT_MEMBRANES	COL15A1 LAMA5 PAPLN NTN1	1.03e-05	40	89	4	M5887
Coexpression	NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON	THEM6 ZNF34 RECQL4 GPT CSMD3 DENND3	1.62e-05	157	89	6	M17936
Coexpression	NABA_CORE_MATRISOME	VWF COL15A1 LAMA5 PAPLN NTN1 VWCE SSPOP	3.82e-05	270	89	7	MM17057
Coexpression	YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN	CDKN2B GJA1 COL15A1	4.14e-05	20	89	3	M4435
Coexpression	YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN	CDKN2B GJA1 COL15A1	4.14e-05	20	89	3	MM637
Coexpression	NABA_CORE_MATRISOME	VWF COL15A1 LAMA5 PAPLN NTN1 VWCE SSPOP	4.29e-05	275	89	7	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	VWF LAMA5 PAPLN NTN1 VWCE SSPOP	4.87e-05	191	89	6	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	VWF LAMA5 PAPLN NTN1 VWCE SSPOP	5.62e-05	196	89	6	M3008
Coexpression	OHM_METHYLATED_IN_ADULT_CANCERS	CDKN2B FANCF SFRP1	1.04e-04	27	89	3	M1233
ToppCell	Transverse-T_cell-Tfh\|Transverse / Region, Cell class and subclass	DLGAP1 ADAM23 FGFBP3 CARF SH2D3A APBA2 CAPN5 NCAPG2	7.90e-09	199	91	8	cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCell	Transverse-(1)_T_cell-(16)_Tfh\|Transverse / shred on region, Cell_type, and subtype	DLGAP1 ADAM23 FGFBP3 CARF SH2D3A APBA2 CAPN5 NCAPG2	7.90e-09	199	91	8	aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF COL15A1 EFNB3 ADAMTS9 LAMA5 PLXND1	1.59e-07	196	91	7	c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCell	Transverse-T_cell-Tfh\|T_cell / Region, Cell class and subclass	DLGAP1 FGFBP3 CARF APBA2 NSD1 CAPN5 NCAPG2	1.76e-07	199	91	7	33ffea12b8228e0b5bd8942531c3b21d24224725
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	FAM234B ADAM23 POR CYP4F3 PCCB CYP4F11	1.10e-06	164	91	6	81c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GJA1 ADAMTS9 FRMPD2 PAPLN CYP4F3 CYP4F12	1.66e-06	176	91	6	2bc4d3ddc2f752d8255dec0e7a9b87c7f82a372d
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GJA1 VWF ADAMTS9 ADAM23 PLXND1 MGAT5B	3.19e-06	197	91	6	a78111171819db746af7b162c77f9a324453f3ce
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	GJA1 VWF COL15A1 ADAMTS9 LAMA5 MGAT5B	3.19e-06	197	91	6	f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	GJA1 VWF COL15A1 ADAMTS9 LAMA5 MGAT5B	3.19e-06	197	91	6	1a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GJA1 VWF COL15A1 ADAMTS9 LAMA5 MGAT5B	3.19e-06	197	91	6	96d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GJA1 VWF COL15A1 ADAMTS9 ADAM23 LAMA5	3.48e-06	200	91	6	a3b09580738783c6bff31ea33d5188912e56b8a7
ToppCell	Healthy-CD4+_T_activated\|Healthy / disease group, cell group and cell class	PCNX2 DLGAP1 CPT1C VWCE NCAPG2	1.21e-05	145	91	5	45e8089fdf7d6f69b383816d8945e39fba24c873
ToppCell	BAL-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	RECQL4 CR1L ZNF598 NCAPG2 DNAH14	1.61e-05	154	91	5	0121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma\|TCGA-Brain / Sample_Type by Project: Shred V9	TRIM67 ZC3H12B CSMD3 EPHA10 PHLPP2	2.00e-05	161	91	5	5f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFRP1 VWF MICAL2 NTN1 GP1BA	2.38e-05	167	91	5	f01b96173deda0239fa482989873cf308e49d48c
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFRP1 VWF MICAL2 NTN1 GP1BA	2.38e-05	167	91	5	5fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GJA1 GPT PAPLN CYP4F12 VWCE	2.38e-05	167	91	5	5c0ede7783403f1c8004cf8c45785687e89046c6
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 ADAM23 PLXND1 TRIM37 GP1BA	2.75e-05	172	91	5	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PRICKLE4 ADAMTS7 RECQL4 CAGE1	2.80e-05	85	91	4	bb9555652e93620d5aeeb71e915b3978a437407d
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PRICKLE4 ADAMTS7 RECQL4 CAGE1	2.80e-05	85	91	4	f7935c3206310adafdecb75149c3b06c38e7780c
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PRICKLE4 ADAMTS7 RECQL4 CAGE1	2.80e-05	85	91	4	43f6911b032718d8ba75fb7bba5f9b536a4b3260
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF TRIM67 MDC1 PLXND1 GP1BA	2.82e-05	173	91	5	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 ADAM23 PLXND1 TRIM37 GP1BA	3.07e-05	176	91	5	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 ADAM23 PLXND1 TRIM37 GP1BA	3.07e-05	176	91	5	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GJA1 ADAMTS9 FRMPD2 PAPLN CYP4F12	3.15e-05	177	91	5	191c14e0ef162536028b841f3759aaddef59b49d
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDKN2B GJA1 ZC3H12B CR1L EPHA10	3.24e-05	178	91	5	f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF MICAL2 CR1L GP1BA	3.32e-05	179	91	5	1c0c0647a111f691dae55f4ed8c51006059ce020
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 ADAMTS9 MICAL2 PAPLN GP1BA	3.32e-05	179	91	5	dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF COL15A1 ADAMTS7 DENND3	3.41e-05	180	91	5	efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell	AT1_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	CDKN2B GJA1 LAMA5 ZC3H12B DENND3	3.41e-05	180	91	5	e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 SFRP1 ADAM23 CARF CSMD3	3.60e-05	182	91	5	a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7\|TCGA-Prostate / Sample_Type by Project: Shred V9	THEM6 FANCF ENTR1 SSPOP EPHA10	3.60e-05	182	91	5	af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF ADAMTS9 LAMA5 PLXND1	3.69e-05	183	91	5	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 SFRP1 ADAM23 APBA2 CSMD3	3.79e-05	184	91	5	a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GJA1 FRMPD2 PAPLN CYP4F12 CYP4F11	3.79e-05	184	91	5	22c18964818fc9c8f18051f836d718937b0d8d12
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF ADAMTS9 MICAL2 PLXND1	3.89e-05	185	91	5	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 ADAM23 LAMA5 PLXND1 TRIM37	3.89e-05	185	91	5	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ADAMTS9 PLXND1 TRIM37 DENND3	3.89e-05	185	91	5	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	droplet-Liver-Npc-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FANCF ADAM23 HDAC8 TRIM37 DENND3	3.99e-05	186	91	5	75258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 SFRP1 ADAM23 APBA2 CSMD3	3.99e-05	186	91	5	d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFRP1 VWF MICAL2 NTN1 PLXND1	3.99e-05	186	91	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	THEM6 VWF PLXND1 THSD7B DENND3	4.09e-05	187	91	5	03de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell	Control-Endothelial-VE_Peribronchial\|Control / Disease state, Lineage and Cell class	GJA1 VWF COL15A1 ADAMTS9 ADAM23	4.20e-05	188	91	5	f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	THEM6 VWF COL15A1 THSD7B DENND3	4.20e-05	188	91	5	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF COL15A1 ADAMTS9 LAMA5 PLXND1	4.20e-05	188	91	5	a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	GJA1 VWF COL15A1 ADAMTS9 ADAM23	4.31e-05	189	91	5	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 SLC34A1 KIAA1549 PAPLN CYP4F3	4.31e-05	189	91	5	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 SLC34A1 KIAA1549 PAPLN CYP4F3	4.31e-05	189	91	5	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDKN2B NTN1 CYP4F3 CYP4F12 CAPN5	4.41e-05	190	91	5	6ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	VWF COL15A1 ADAMTS9 ADAM23 MGAT5B	4.41e-05	190	91	5	ac2eb1e51459d187095152e0cd41ae54c1025c6f
ToppCell	T_cells-Effector_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PCNX2 ADAM23 APBA2 TNFAIP3 PLXND1	4.41e-05	190	91	5	13dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	VWF COL15A1 ADAMTS9 ADAM23 MGAT5B	4.41e-05	190	91	5	6010f16378f2d9cde37c7e7db6a7d9666edaddcc
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFRP1 VWF MICAL2 NTN1 PLXND1	4.53e-05	191	91	5	6e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFRP1 VWF MICAL2 NTN1 PLXND1	4.53e-05	191	91	5	482db995930346be69072ace2fd78fd453e97fb5
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF ADAMTS9 LAMA5 PLXND1	4.64e-05	192	91	5	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJA1 VWF COL15A1 ADAMTS9 ADAM23	4.64e-05	192	91	5	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJA1 VWF COL15A1 ADAMTS9 ADAM23	4.87e-05	194	91	5	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJA1 VWF COL15A1 ADAMTS9 ADAM23	4.87e-05	194	91	5	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	PCW_05-06-Endothelial-Endothelial_immature\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	THEM6 VWF COL15A1 PLXND1 THSD7B	4.87e-05	194	91	5	9bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCell	PCW_05-06-Endothelial-Endothelial_mature\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	THEM6 VWF COL15A1 THSD7B DENND3	4.99e-05	195	91	5	54fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRIM67 CYP4F3 TNFAIP3 THSD7B DNAH14	4.99e-05	195	91	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRIM67 CYP4F3 TNFAIP3 THSD7B DNAH14	4.99e-05	195	91	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	IPF-Endothelial-VE_Peribronchial\|IPF / Disease state, Lineage and Cell class	GJA1 VWF COL15A1 ADAMTS9 ADAM23	4.99e-05	195	91	5	2c3ad3cb79f11119ac69c413a938d21199145040
ToppCell	control-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RASAL3 USP42 MICAL2 TNFAIP3 PLXND1	4.99e-05	195	91	5	66959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.12e-05	196	91	5	5609b2d93172a488b35d854298a3a4e504e17e28
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF COL15A1 ADAMTS9 PLXND1	5.12e-05	196	91	5	629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCell	distal-Endothelial-Bronchial_Vessel_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.24e-05	197	91	5	f45a93b5ad80a16b760acbaa6467648ffc05a0d3
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	GJA1 SH2D3A POR DENND3 PLXNB1	5.37e-05	198	91	5	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CDKN2B MICAL2 PLXND1 CR1 DENND3	5.37e-05	198	91	5	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF COL15A1 ADAMTS9 PLXND1	5.37e-05	198	91	5	f7a957e8f09d54a55a5dbecfaa9cdf01e6fd543d
ToppCell	distal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.37e-05	198	91	5	00fdee373eaa43c9ce897f2ba2ecbe94cedea93a
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF ADAMTS9 LAMA5 PLXND1	5.50e-05	199	91	5	07bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	RECQL4 ELANE CYP4F3 NCAPG2 PLXNB1	5.50e-05	199	91	5	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GJA1 VWF COL15A1 ADAMTS9 PLXND1	5.50e-05	199	91	5	97052c28e354833901f28d339b09f97f50a5b752
ToppCell	3'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF COL15A1 ADAMTS9 LAMA5 PLXND1	5.50e-05	199	91	5	f5c8ad751d21ea0b199a02846faecd04bf100033
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.50e-05	199	91	5	6a7ecc3a68b9cfc49e50abaeb16e2eee3795377e
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GJA1 VWF COL15A1 ADAMTS9 LAMA5	5.50e-05	199	91	5	6fb81388c5045e81c3849a7136bdff3f953f044e
ToppCell	3'-Adult-LargeIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF ADAMTS9 LAMA5 PLXND1	5.63e-05	200	91	5	74a3b9ec8faa1d187ad8b0d12f5c89bde2d7248e
ToppCell	proximal-Endothelial-Bronchial_Vessel_1\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.63e-05	200	91	5	d034bd210c87b704acf45f50d888497c8737011b
ToppCell	5'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 VWF ADAMTS9 LAMA5 PLXND1	5.63e-05	200	91	5	2554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCell	proximal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.63e-05	200	91	5	0ff4185021ec84b57be13b28495e2f8a4d195eb6
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.63e-05	200	91	5	310c75e13be9194312a8b686804edcf13d44caf5
ToppCell	3'-Adult-LymphNode-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF COL15A1 ADAMTS9 LAMA5 PLXND1	5.63e-05	200	91	5	663e2b4672f193844bb9bf4873749114977c19b3
ToppCell	proximal-Endothelial-Bronchial_Vessel_1-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GJA1 VWF COL15A1 ADAMTS9 ADAM23	5.63e-05	200	91	5	e4f6e0b9502eb531f28d605f9dbda6a72a9ed320
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF34 RECQL4 NTN1 THSD7B	1.69e-04	135	91	4	52b5c664c0b7a303c6084d508748dcb6c38a0c23
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM67 USP29 KLHDC7A SSPOP	1.79e-04	137	91	4	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM67 USP29 KLHDC7A SSPOP	1.79e-04	137	91	4	c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFNB3 GPT KNDC1 SSPOP	1.84e-04	138	91	4	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	Healthy-CD4+_T_activated\|World / disease group, cell group and cell class	PCNX2 DLGAP1 CPT1C VWCE	1.95e-04	140	91	4	407691970ec72a3afb45e431cf48814546b8acff
ToppCell	NS-critical-d_07-13-Epithelial-unknown_epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDKN2B ADAMTS7 LAMA5 PLXNB1	2.00e-04	141	91	4	33ad925ff7be3c682741a6328216a89f9d4033e9
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFNB3 GPT KNDC1 SSPOP	2.05e-04	142	91	4	67d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	PPP1R12B FBXL17 CR1 GP1BA	2.05e-04	142	91	4	0e0f8bb956ff89dc98e8fa56f8acac33e01a26dd
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCNX2 RECQL4 KNDC1 ELANE	2.17e-04	144	91	4	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL15A1 LAMA5 NTN1 MGAT5B	2.28e-04	146	91	4	47368f981180ca6a8c81a50f7f9430f12456f609
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FSCN3 CAGE1 VWCE CSMD3	2.28e-04	146	91	4	bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCell	E16.5-samps-Mesenchymal-Pericyte\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COPS7B PAPLN EPHA10 TDRD12	2.41e-04	148	91	4	e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCell	E16.5-samps-Mesenchymal-Pericyte-pericyte_A\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COPS7B PAPLN EPHA10 TDRD12	2.41e-04	148	91	4	c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFNB3 GPT KNDC1 SSPOP	2.53e-04	150	91	4	afd651c654e715414eff64cf3a37378d057a56a2
ToppCell	Children_(3_yrs)-Immune-mast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM23 FGFBP3 KIAA1549 THSD7B	2.73e-04	153	91	4	d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS9 LMX1B FSCN3 CR1	2.87e-04	155	91	4	90e629681a72baacc7981b82883866a487638dbc
Disease	von Willebrand disorder	VWF GP1BA	8.20e-06	2	85	2	cv:C0042974
Disease	Hereditary von Willebrand disease	VWF GP1BA	8.20e-06	2	85	2	cv:C5703318
Disease	double outlet right ventricle (implicated_via_orthology)	CFC1 CFC1B	2.46e-05	3	85	2	DOID:6406 (implicated_via_orthology)
Disease	dextro-looped transposition of the great arteries (implicated_via_orthology)	CFC1 CFC1B	4.90e-05	4	85	2	DOID:0060770 (implicated_via_orthology)
Disease	superoxide dismutase [Mn]; mitochondrial measurement	SLC34A1 NSD1	4.90e-05	4	85	2	EFO_0021981
Disease	right atrial isomerism (implicated_via_orthology)	CFC1 CFC1B	4.90e-05	4	85	2	DOID:0060856 (implicated_via_orthology)
Disease	Bernard-Soulier syndrome (is_implicated_in)	VWF GP1BA	4.90e-05	4	85	2	DOID:2217 (is_implicated_in)
Disease	scoliosis (implicated_via_orthology)	ADAMTS9 SSPOP	8.15e-05	5	85	2	DOID:0060249 (implicated_via_orthology)
Disease	blood sedimentation	CR1 CR1L	1.71e-04	7	85	2	EFO_0004304
Disease	developmental disorder of mental health (implicated_via_orthology)	RASAL3 PLXND1 PLXNB1	3.86e-04	49	85	3	DOID:0060037 (implicated_via_orthology)
Disease	hypertension (biomarker_via_orthology)	GJA1 VWF HDAC8 CYP4F12 CYP4F11	5.13e-04	227	85	5	DOID:10763 (biomarker_via_orthology)
Disease	visceral heterotaxy (is_implicated_in)	CFC1 CFC1B	5.31e-04	12	85	2	DOID:0050545 (is_implicated_in)
Disease	Lymphoma, Large-Cell, Follicular	KMT2D TNFAIP3	8.40e-04	15	85	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	KMT2D TNFAIP3	8.40e-04	15	85	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	KMT2D TNFAIP3	8.40e-04	15	85	2	C0079758
Disease	Proteinuria	VWF ADAMTS7	8.40e-04	15	85	2	HP_0000093
Disease	Lymphoma, Follicular, Grade 2	KMT2D TNFAIP3	8.40e-04	15	85	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	KMT2D TNFAIP3	8.40e-04	15	85	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	KMT2D TNFAIP3	8.40e-04	15	85	2	C1956130
Disease	transient cerebral ischemia (implicated_via_orthology)	VWF ELANE PLXND1	8.47e-04	64	85	3	DOID:224 (implicated_via_orthology)
Disease	Coronary Arteriosclerosis	CDKN2B ADAMTS7 IRAK1	8.86e-04	65	85	3	C0010054
Disease	Coronary Artery Disease	CDKN2B ADAMTS7 IRAK1	8.86e-04	65	85	3	C1956346
Disease	serum alanine aminotransferase measurement	DLGAP1 ADAMTS7 ADAMTS9 RECQL4 GPT IRAK1 LAMA5 FBXL17 PCCB	8.92e-04	869	85	9	EFO_0004735
Disease	renovascular hypertension (biomarker_via_orthology)	GJA1 HDAC8	1.36e-03	19	85	2	DOID:1591 (biomarker_via_orthology)
Disease	Lymphoma, Follicular	KMT2D TNFAIP3	1.51e-03	20	85	2	C0024301
Disease	stomach carcinoma (is_marker_for)	MDC1 TNFAIP3	2.17e-03	24	85	2	DOID:5517 (is_marker_for)
Disease	creatinine measurement	GTF2B ADAMTS7 SLC34A1 NSD1 LAMA5 FBXL17 POR KLHDC7A TDRD12	2.26e-03	995	85	9	EFO_0004518
Disease	complement factor D measurement	GJA1 ZNF609 ELANE	2.48e-03	93	85	3	EFO_0020283
Disease	Neurodevelopmental Disorders	DLGAP1 LMX1B PLXNB1	2.48e-03	93	85	3	C1535926
Disease	white matter integrity, age at assessment	CARF NTN1	2.55e-03	26	85	2	EFO_0004641, EFO_0008007

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSDLPPHCTRAQCQP	nan	86	A8MWP4
HCRPRALCVINPGNP	GPT	231	P24298
TDCSIRDPVRNLHPP	ADAM23	766	O75077
LLPDCSPCEERLNPA	CAGE1	591	Q8TC20
HNECPDPGIPINARR	CSMD3	831	Q7Z407
AERECPPHAEQRQPT	COPS7B	236	Q9H9Q2
HCQQPLPDRVPSTAI	APCDD1L	36	Q8NCL9
ELCEENLNPNAHPRP	DLGAP1	851	O14490
LRPESPAPEEQECHN	APBA2	51	Q99767
VPSNCRELRLDEPPH	CAPN5	491	O15484
LHCLPLQTPDRCDPK	CFC1B	146	P0CG36
PPQRVPLEDCSEINC	DENND3	1111	A2RUS2
LHCLPLQTPDRCDPK	CFC1	146	P0CG37
PVVNDVNPCELHCRP	ADAMTS7	621	Q9UKP4
AQPDPCSDENGHPRR	NTN1	36	O95631
CPASELPEHQARLRN	RASAL3	546	Q86YV0
PAEICHPRAVPSNID	NSD1	1771	Q96L73
PPDPREHCSRLLSNN	TSPOAP1	1421	O95153
PNPRADPECCSILHG	INTS13	111	Q9NVM9
RPASCAPDELSPEQH	KIAA1549	56	Q9HCM3
RRPCHDPAPLQARLC	FGFBP3	121	Q8TAT2
ELHNRFQSLCQAPPP	FANCF	306	Q9NPI8
TCPQDFPHCSIPLRV	MDC1	2041	Q14676
LQDCPSLRPPIDHLC	POR	431	P16435
SSDHQACCIPRPLPL	FOXD4L3	356	Q6VB84
VRDENCALPSRLHPQ	CARF	406	Q8N187
QDFCRAPDPALPEAH	MGAT5B	641	Q3V5L5
SQATRHLSEPCEPPD	PCNX2	2076	A6NKB5
RVECEPPPDTQCHVT	PLXNB1	966	O43157
SPLCHAPQLPQASCE	PLXND1	101	Q9Y4D7
APQLPQASCEHPRRL	PLXND1	106	Q9Y4D7
CAFLIPCPPRDLHST	FAM234B	121	A2RU67
RPLCSPCPEHSRALE	EPHA10	296	Q5JZY3
PNHPLDSPHVCRRCN	LAMA5	416	O15230
LEDRLHCQTQACPPL	IRAK1	296	P51617
TCPCGEVLERHEPLP	SLC34A1	61	Q06495
APVRECHDPSDRLVP	PCCB	286	P05166
HAELLRPRCPACDQL	PRICKLE4	141	Q2TBC4
QFQRILDDPSPACPH	CPT1C	361	Q8TCG5
DKPPDREQCNTHACP	ADAMTS9	1426	Q9P2N4
AHVEAEPLVARCPPC	KLHL21	236	Q9UJP4
CHLEPVRCQAPPPRS	CACNA1G	561	O43497
VCQPPPDVLHAERTQ	CR1	296	P17927
VCQPPPDVLHAERTQ	CR1	746	P17927
CSRVCQPPPEILHGE	CR1	1646	P17927
RDQPQRPSHLCECPE	LINC00322	186	Q6ZN03
NSRPCCLPLGHQPRI	DEFB108A	51	A8MXU0
QLNCERPHGRDLDSP	ENTR1	36	Q96C92
PAAQAPECLHPCRVS	FRMPD2	221	Q68DX3
RESPENPCDCHREPP	FBXL17	301	Q9UF56
LHPPVPVISRCCTQD	CYP4F11	391	Q9HBI6
SRVCQPPPDVLHAER	CR1L	286	Q2VPA4
LHPPAPFISRCCTQD	CYP4F12	391	Q9HCS2
PCPHQVDCFLSRPTE	GJA1	191	P17302
QDQPDRIHLLPCRPG	FSCN3	411	Q9NQT6
EPNCADPATLTRPVH	CDKN2B	71	P42772
HRENIPFCPSLEPDS	DNAH14	1786	Q0VDD8
RNDPFLHPDFCCLLP	GP1BA	516	P07359
EVCPLNQARPHCRLV	KLHDC7A	571	Q5VTJ3
CLACLRALQTRPEHP	KNDC1	466	Q76NI1
IQRSEDNPCPHPRDP	ELANE	246	P08246
LHPPVPAVSRCCTQD	CYP4F3	391	Q08477
LEITPSCRPDRNEPH	HDAC8	346	Q9BY41
QLTVHPDPRTPEELC	COL15A1	221	P39059
RCEAPPAPNLLLTCD	EFNB3	91	Q15768
SPQCPEEPRAVHAAL	MICAL2	1216	O94851
CPHCRAPLQLRELVN	TRIM37	51	O94972
DPLQERPCNLPSCTE	SSPOP	3921	A2VEC9
HLCQRRVEPPELPAD	THEM6	166	Q8WUY1
HRCPPLAVCLAQQLP	RECQL4	961	O94761
CPDRHRINPETDLPR	TDRD12	856	Q587J7
SSDHQACCIPRPLPL	FOXD4L6	356	Q3SYB3
PQCVDIPADLRLCHN	SFRP1	56	Q8N474
HCLNACIQRAVREPP	NCAPG2	576	Q86XI2
TPPVCDPCPERIQNH	ZNF837	141	Q96EG3
AICQLCDRTPPEPAA	TRIM67	206	Q6ZTA4
ARSEEPCEQPLLVHP	USP42	861	Q9H9J4
RCHPLVDPEPFVALC	VWF	236	P04275
SCDLPPVPHCERGLQ	VWF	2331	P04275
DPPKQRCRAPACDHF	TNFAIP3	756	P21580
IHCCRGRDLENSPPL	PHLPP2	1171	Q6ZVD8
QPRPADRRSCNLHPC	PAPLN	346	O95428
EDRPPLTEPCVHEDC	PAPLN	466	O95428
RLDALPRVTCPNHPD	GTF2B	6	Q00403
CPHDAPSCLLGPQNR	SH2D3A	281	Q9BRG2
CPHCADAFPQLPELR	ZNF408	526	Q9H9D4
DRNCPSPVLIDCPHP	ZNF609	486	O15014
DCVDSCPHPIRIPGQ	VWCE	606	Q96DN2
SPLEPEHSQGDPRCN	USP29	256	Q9HBJ7
PHRQLCRSPCLDRPS	ZC3H12B	76	Q5HYM0
QHECPRCPELPPFSL	ZNF598	116	Q86UK7
KPCPPSQALQEHRLC	THSD7B	641	Q9C0I4
VPCSLRHPRQDLCGE	nan	76	Q96M66
PLCDQCFPPTKIERH	UIMC1	506	Q96RL1
SRPVPDQRPHKCDIC	ZNF34	186	Q8IZ26
QSEEPCLSPRPEESH	KMT2D	836	O14686
PHPAVCEGCQRPISD	LMX1B	51	O60663
SLDEEPICHRLRCPA	PPP1R12B	711	O60237