Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA methyltransferase activity	METTL2A PCIF1	6.63e-05	67	4	2	GO:0008173
GeneOntologyMolecularFunction	S-adenosylmethionine-dependent methyltransferase activity	METTL2A PCIF1	4.38e-04	172	4	2	GO:0008757
GeneOntologyMolecularFunction	methyltransferase activity	METTL2A PCIF1	6.70e-04	213	4	2	GO:0008168
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	METTL2A PCIF1	7.41e-04	224	4	2	GO:0016741
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	METTL2A PCIF1	2.54e-03	417	4	2	GO:0140098
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	METTL2A PCIF1	5.99e-03	645	4	2	GO:0140640
GeneOntologyBiologicalProcess	methylation	METTL2A PCIF1	7.57e-04	234	4	2	GO:0032259
Pubmed	Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.	METTL2A ZNRD2	3.61e-05	86	4	2	19501082
Coexpression	GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP	ZNRD2 PCIF1	3.37e-04	198	4	2	M6120
Coexpression	GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN	ZNRD2 PCIF1	1.89e-03	471	4	2	M19016
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	DERL1 PCIF1	3.89e-03	680	4	2	M41089
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_7DY_DN	DERL1 PCIF1	5.95e-03	844	4	2	M41129
Coexpression	HOUNKPE_HOUSEKEEPING_GENES	DERL1 PCIF1	1.05e-02	1129	4	2	M42508
Coexpression	HOUNKPE_HOUSEKEEPING_GENES	DERL1 PCIF1	1.10e-02	1158	4	2	MM1338
Coexpression	HAY_BONE_MARROW_ERYTHROBLAST	METTL2A ZNRD2	1.32e-02	1271	4	2	M39197
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Mesenchymal-Unfolded_protein_responsible_cell\|1m / Sample Type, Dataset, Time_group, and Cell type.	DERL1 ZNRD2	1.17e-04	200	4	2	7cd66af5427f9850a8200686201ca18f35a2a025
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Unfolded_protein_responsible_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	DERL1 ZNRD2	1.17e-04	200	4	2	e68e44ab57d17ac4845d9e3798814d048d79e888
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal\|10w / Sample Type, Dataset, Time_group, and Cell type.	DERL1 ZNRD2	1.17e-04	200	4	2	c968d077b7fd24fb06cedb51c737996f25667eb7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Unfolded_protein_responsible_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	DERL1 ZNRD2	1.17e-04	200	4	2	bc479baca21f0ff19a1c4efdb9530f289a1ab115
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Macroglial-Glia_progenitor_cell\|1m / Sample Type, Dataset, Time_group, and Cell type.	DERL1 ZNRD2	1.17e-04	200	4	2	26940eee4a2f2aafd857964b5607e7dfb65f8d6f
Drug	Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; HL60; HG-U133A	ZNRD2 PCIF1	4.20e-04	192	4	2	1616_UP
Drug	2-propylpentanoic acid; Down 200; 1000uM; SKMEL5; HG-U133A	DERL1 PCIF1	4.24e-04	193	4	2	629_DN
Drug	LY294002; Down 200; 10uM; HL60; HG-U133A	DERL1 ZNRD2	4.29e-04	194	4	2	361_DN
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A	ZNRD2 PCIF1	4.37e-04	196	4	2	2936_DN
Drug	Acenocoumarol [152-72-7]; Up 200; 11.4uM; HL60; HG-U133A	DERL1 PCIF1	4.42e-04	197	4	2	1394_UP
Drug	Flumequine [42835-25-6]; Up 200; 15.4uM; HL60; HG-U133A	DERL1 ZNRD2	4.42e-04	197	4	2	1429_UP
Drug	Metolazone [17560-51-9]; Up 200; 11uM; HL60; HG-U133A	ZNRD2 PCIF1	4.46e-04	198	4	2	2014_UP
Drug	Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; HL60; HG-U133A	DERL1 PCIF1	4.46e-04	198	4	2	1404_DN
Drug	Famotidine [76824-35-6]; Up 200; 11.8uM; HL60; HG-U133A	ZNRD2 PCIF1	4.46e-04	198	4	2	2029_UP
Drug	Haloperidol [52-86-8]; Up 200; 10.6uM; HL60; HG-U133A	DERL1 PCIF1	4.51e-04	199	4	2	2039_UP
Drug	Vinpocetine [42971-09-5]; Down 200; 11.4uM; HL60; HG-U133A	DERL1 ZNRD2	4.51e-04	199	4	2	1557_DN
Drug	cylindrospermopsin	METTL2A ZNRD2	2.49e-03	471	4	2	ctd:C089595
Drug	Glafenine	DERL1 ZNRD2	1.88e-02	1327	4	2	ctd:D005897
Disease	memory performance	DERL1 PCIF1	1.13e-03	409	4	2	EFO_0004874
Disease	mean reticulocyte volume	DERL1 PCIF1	4.24e-03	799	4	2	EFO_0010701

Protein segments in the cluster

Peptide	Gene	Start	Entry
LMFRYPMDLGGRNFL	DERL1	186	Q9BUN8
LLKPGGMMLLRDYGR	METTL2A	281	Q96IZ6
LLRRYQMMFGVGLYE	PCIF1	471	Q9H4Z3
RLMGDYLLRGYRMLG	ZNRD2	36	O60232