Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

RAF1 CDKL2 ADCK1 OBSCN STK32C CDKL1 CDKL5 TGFBR3 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

2.04e-0644613514GO:0004674
GeneOntologyMolecularFunctionprotein kinase activity

RAF1 DDR1 CDKL2 ADCK1 DDR2 OBSCN STK32C CDKL1 CDKL5 TGFBR3 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

3.05e-0660013516GO:0004672
GeneOntologyMolecularFunctionprotein serine kinase activity

RAF1 CDKL2 OBSCN STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

6.77e-0636313512GO:0106310
GeneOntologyMolecularFunctioncollagen binding

DPP4 DDR1 DDR2 AEBP1 TLL1 NID1

1.83e-05811356GO:0005518
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

RAF1 DDR1 CDKL2 ADCK1 DDR2 OBSCN STK32C CDKL1 CDKL5 TGFBR3 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

2.44e-0570913516GO:0016773
GeneOntologyMolecularFunctionprotein tyrosine kinase collagen receptor activity

DDR1 DDR2

4.54e-0521352GO:0038062
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase activity

CDKL2 CDKL1 CDKL5 CDK11B

4.78e-05301354GO:0004693
GeneOntologyMolecularFunctioncyclin-dependent protein kinase activity

CDKL2 CDKL1 CDKL5 CDK11B

4.78e-05301354GO:0097472
GeneOntologyMolecularFunctionkinase activity

RAF1 DDR1 CDKL2 ADCK1 DDR2 OBSCN STK32C CDKL1 CDKL5 TGFBR3 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

5.97e-0576413516GO:0016301
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

RAF1 DDR1 CDKL2 ADCK1 DDR2 OBSCN STK32C CDKL1 CDKL5 TGFBR3 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

6.05e-0493813516GO:0016772
GeneOntologyMolecularFunctioncollagen receptor activity

DDR1 DDR2

6.69e-0461352GO:0038064
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

DPP4 DDR1 DDR2 LAMC1 TGFBR3 AEBP1 NID1

1.45e-06841377GO:1903053
GeneOntologyBiologicalProcessextracellular matrix organization

DPP4 DDR1 ST7 DDR2 LAMC1 TGFBR3 ADAMTSL5 AEBP1 TLL1 WNT3A NID1 MMP2

8.35e-0637713712GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

DPP4 DDR1 ST7 DDR2 LAMC1 TGFBR3 ADAMTSL5 AEBP1 TLL1 WNT3A NID1 MMP2

8.57e-0637813712GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

DPP4 DDR1 ST7 DDR2 LAMC1 TGFBR3 ADAMTSL5 AEBP1 TLL1 WNT3A NID1 MMP2

8.80e-0637913712GO:0045229
GeneOntologyBiologicalProcessSchwann cell development

RAF1 AKT1 AKT2 MAPK1 PLEC

1.47e-05471375GO:0014044
GeneOntologyBiologicalProcessperipheral nervous system myelin maintenance

AKT1 AKT2 PLEC

2.34e-0591373GO:0032287
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import into cell

EPRS1 AKT1 AKT2

2.34e-0591373GO:0140212
GeneOntologyBiologicalProcessSchwann cell differentiation

RAF1 AKT1 AKT2 MAPK1 PLEC

3.20e-05551375GO:0014037
GeneOntologyBiologicalProcessdevelopmental growth

DDR1 ERCC6 DSCAM KIF26B RBM10 TRPC5 DDR2 SPG11 CDKL5 TGFBR3 LIMK1 DHCR7 WNT3A LRP4 AKT1 KDM2A MAPK1 PLEC

3.43e-0591113718GO:0048589
GeneOntologyBiologicalProcessextracellular matrix disassembly

DPP4 DDR1 DDR2 LAMC1 MMP2

1.43e-04751375GO:0022617
GeneOntologyBiologicalProcessgrowth

PAPPA2 DDR1 ERCC6 DSCAM KIF26B RBM10 TRPC5 DDR2 SPG11 ST7L CDKL5 TGFBR3 LIMK1 DHCR7 WNT3A LRP4 AKT1 KDM2A MAPK1 PLEC

1.91e-04123513720GO:0040007
GeneOntologyBiologicalProcesspositive regulation of developmental growth

DSCAM TRPC5 CDKL5 TGFBR3 LIMK1 WNT3A AKT1 MAPK1

1.95e-042381378GO:0048639
GeneOntologyBiologicalProcessmyelin maintenance

AKT1 AKT2 PLEC

2.17e-04181373GO:0043217
GeneOntologyBiologicalProcesspositive regulation of protein localization to membrane

FNTA AP2B1 WNT3A LRP4 AKT1 AKT2

2.34e-041301376GO:1905477
GeneOntologyBiologicalProcessnegative regulation of long-chain fatty acid import across plasma membrane

AKT1 AKT2

2.60e-0441372GO:0010748
GeneOntologyBiologicalProcessnegative regulation of long-chain fatty acid import into cell

AKT1 AKT2

2.60e-0441372GO:0140213
DomainKinase-like_dom

RAF1 DDR1 CDKL2 ADCK1 DDR2 OBSCN WDR81 STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

1.75e-0654213416IPR011009
DomainProt_kinase_dom

RAF1 DDR1 CDKL2 ADCK1 DDR2 OBSCN STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

2.36e-0648913415IPR000719
DomainPROTEIN_KINASE_DOM

RAF1 DDR1 CDKL2 ADCK1 DDR2 OBSCN STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

2.61e-0649313415PS50011
DomainPROTEIN_KINASE_ATP

RAF1 DDR1 CDKL2 ADCK1 OBSCN STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

5.59e-0645913414PS00107
DomainSer/Thr_kinase_AS

RAF1 CDKL2 OBSCN STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

1.03e-0535713412IPR008271
DomainPROTEIN_KINASE_ST

RAF1 CDKL2 OBSCN STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

1.18e-0536213412PS00108
DomainPkinase

RAF1 CDKL2 OBSCN STK32C CDKL1 CDKL5 LIMK1 BUB1B AKT1 AKT2 CDK11B MAPK1

1.97e-0538113412PF00069
DomainST7

ST7 ST7L

5.11e-0521342PF04184
DomainClathrin_b-adaptin_app_Ig-like

AP1B1 AP2B1

5.11e-0521342IPR013037
Domain-

AP1B1 AP2B1

5.11e-05213422.60.40.1150
DomainST7

ST7 ST7L

5.11e-0521342IPR007311
DomainDDR1/DDR2

DDR1 DDR2

5.11e-0521342IPR029553
DomainAP_complex_bsu_1_2_4

AP1B1 AP2B1

1.53e-0431342IPR016342
DomainB2-adapt-app_C

AP1B1 AP2B1

1.53e-0431342PF09066
Domain-

DDR1 DDR2 LAMC1 LAMC3 AEBP1

1.79e-047313452.60.120.260
DomainS_TKc

RAF1 CDKL2 OBSCN STK32C CDKL1 CDKL5 AKT1 AKT2 CDK11B MAPK1

2.69e-0435913410SM00220
Domain-

SPOUT1 MRM3

3.04e-04413423.40.1280.10
DomainB2-adapt-app_C

AP1B1 AP2B1

3.04e-0441342SM01020
DomaintRNA_m1G_MTases_N

SPOUT1 MRM3

3.04e-0441342IPR029026
DomainB-adaptin_app_sub_C

AP1B1 AP2B1

3.04e-0441342IPR015151
DomainProtein_kinase_ATP_BS

RAF1 CDKL2 OBSCN STK32C CDKL1 CDKL5 LIMK1 AKT1 AKT2 MAPK1

4.12e-0437913410IPR017441
DomainFA58C

DDR1 DDR2 AEBP1

4.37e-04211343SM00231
DomainFA58C_3

DDR1 DDR2 AEBP1

4.37e-04211343PS50022
DomainFA58C_1

DDR1 DDR2 AEBP1

4.37e-04211343PS01285
DomainFA58C_2

DDR1 DDR2 AEBP1

4.37e-04211343PS01286
DomainGRAM

SNAP47 GRAMD4 MTMR2

5.03e-04221343PF02893
DomainGRAM

SNAP47 GRAMD4 MTMR2

5.03e-04221343IPR004182
DomainFerI

FER1L6 OTOF

5.04e-0451342SM01202
DomainFerB

FER1L6 OTOF

5.04e-0451342SM01201
DomainFerlin_B-domain

FER1L6 OTOF

5.04e-0451342IPR012561
DomainAP_beta

AP1B1 AP2B1

5.04e-0451342IPR026739
DomainFerlin_C

FER1L6 OTOF

5.04e-0451342PF16165
DomainFerlin_C

FER1L6 OTOF

5.04e-0451342IPR032362
DomainFerIin_dom

FER1L6 OTOF

5.04e-0451342IPR012968
DomainFerI

FER1L6 OTOF

5.04e-0451342PF08151
DomainFerB

FER1L6 OTOF

5.04e-0451342PF08150
DomainGalactose-bd-like

DDR1 DDR2 LAMC1 LAMC3 AEBP1

5.81e-04941345IPR008979
DomainF5_F8_type_C

DDR1 DDR2 AEBP1

6.55e-04241343PF00754
DomainFA58C

DDR1 DDR2 AEBP1

6.55e-04241343IPR000421
DomainAlpha/beta_knot_MTases

SPOUT1 MRM3

7.52e-0461342IPR029028
DomainBeta2_adaptin/TBP_C_dom

AP1B1 AP2B1

7.52e-0461342IPR012295
Domain-

AP1B1 AP2B1

7.52e-04613423.30.310.10
DomainCoatomer/calthrin_app_sub_C

AP1B1 AP2B1

1.39e-0381342IPR009028
DomainLAMININ_IVA

LAMC1 LAMC3

1.39e-0381342PS51115
DomainLaminin_B

LAMC1 LAMC3

1.39e-0381342PF00052
DomainLamB

LAMC1 LAMC3

1.39e-0381342SM00281
DomainLaminin_IV

LAMC1 LAMC3

1.39e-0381342IPR000034
DomainAlpha_adaptinC2

AP1B1 AP2B1

1.78e-0391342PF02883
DomainBEACH

WDR81 WDFY4

1.78e-0391342PS50197
DomainBeach

WDR81 WDFY4

1.78e-0391342PF02138
Domain-

WDR81 WDFY4

1.78e-03913421.10.1540.10
DomainBeach

WDR81 WDFY4

1.78e-0391342SM01026
DomainClathrin_a/b/g-adaptin_app_Ig

AP1B1 AP2B1

1.78e-0391342IPR008152
DomainBEACH_dom

WDR81 WDFY4

1.78e-0391342IPR000409
DomainAlpha_adaptinC2

AP1B1 AP2B1

1.78e-0391342SM00809
DomainEGF-like_dom

SELL LAMC1 LAMC3 TLL1 LRP4 NID1 C8A

2.15e-032491347IPR000742
DomainEGF_1

SELL LAMC1 LAMC3 TLL1 LRP4 NID1 C8A

2.46e-032551347PS00022
DomainTyr_kinase_rcpt_2_CS

DDR1 DDR2

2.69e-03111342IPR002011
DomainEGF-like_CS

SELL LAMC1 LAMC3 TLL1 LRP4 NID1 C8A

2.80e-032611347IPR013032
DomainEGF_2

SELL LAMC1 LAMC3 TLL1 LRP4 NID1 C8A

3.05e-032651347PS01186
DomainCoatomer/clathrin_app_Ig-like

AP1B1 AP2B1

3.22e-03121342IPR013041
DomainRECEPTOR_TYR_KIN_II

DDR1 DDR2

3.22e-03121342PS00239
DomainCarboxyPept_regulatory_dom

CPD AEBP1

3.78e-03131342IPR014766
Domain-

CPD AEBP1

3.78e-031313422.60.40.1120
DomainAcyl_CoA_acyltransferase

NAT16 ATE1 OAZ3

4.11e-03451343IPR016181
Domain6-blade_b-propeller_TolB-like

LRP4 NID1 EIF3B

4.38e-03461343IPR011042
DomainATPase_dyneun-rel_AAA

MDN1 DNAH11

4.39e-03141342IPR011704
DomainLdl_recept_b

LRP4 NID1

4.39e-03141342PF00058
DomainLDLRB

LRP4 NID1

4.39e-03141342PS51120
DomainAAA_5

MDN1 DNAH11

4.39e-03141342PF07728
DomainClathrin/coatomer_adapt-like_N

AP1B1 AP2B1

5.05e-03151342IPR002553
DomainLY

LRP4 NID1

5.05e-03151342SM00135
DomainAdaptin_N

AP1B1 AP2B1

5.05e-03151342PF01602
DomainLDLR_classB_rpt

LRP4 NID1

5.05e-03151342IPR000033
DomainGrowth_fac_rcpt_

LAMC1 LAMC3 LRP4 NID1 C8A

5.37e-031561345IPR009030
DomainGRAM

GRAMD4 MTMR2

5.74e-03161342SM00568
DomainLaminin_N

LAMC1 LAMC3

5.74e-03161342IPR008211
DomainLamNT

LAMC1 LAMC3

5.74e-03161342SM00136
DomainLAMININ_NTER

LAMC1 LAMC3

5.74e-03161342PS51117
DomainLaminin_N

LAMC1 LAMC3

5.74e-03161342PF00055
DomainCarboxyPept-like_regulatory

CPD AEBP1

6.48e-03171342IPR008969
DomainEGF

SELL LAMC1 LAMC3 TLL1 LRP4 NID1

7.03e-032351346SM00181
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

DDR1 CAPN1 DDR2 LAMC1 LAMC3 SH3PXD2A TLL1 LRP4 NID1 MMP2 PLEC

5.39e-063009511M610
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

AKT1 AKT2 MAPK1

2.42e-059953MM15666
PathwaySIG_IL4RECEPTOR_IN_B_LYPHOCYTES

RAF1 AKT1 AKT2 MAPK1

3.02e-0527954M1718
PathwayWP_NRP1TRIGGERED_SIGNALING_IN_PANCREATIC_CANCER

TGFBR3 AKT1 AKT2 MMP2 MAPK1

3.04e-0554955M42568
PathwayKEGG_ACUTE_MYELOID_LEUKEMIA

RAF1 ZBTB16 AKT1 AKT2 MAPK1

3.97e-0557955M19888
PathwayWP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS

RAF1 TGFBR3 WNT3A AKT1

4.04e-0529954M39516
PathwayWP_ACUTE_MYELOID_LEUKEMIA

RAF1 ZBTB16 AKT1 AKT2 MAPK1

9.32e-0568955M48322
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

RAF1 CDKL2 WNT3A AKT1 AKT2 MMP2 MAPK1

1.06e-04161957M39770
PathwayWP_KISSPEPTINKISSPEPTIN_RECEPTOR_SYSTEM_IN_THE_OVARY

RAF1 AKT1 AKT2 MAPK1

1.33e-0439954M39905
PathwayWP_EFFECT_OF_OMEGA3_PUFA_ON_HUNTINGTONS_DISEASE_PATHWAYS

GABRB3 RAF1 DHCR7 AKT1 AKT2 MAPK1

1.50e-04119956M48309
PathwayWP_TNFRELATED_WEAK_INDUCER_OF_APOPTOSIS_TWEAK_SIGNALING

RAF1 AKT1 AKT2 MAPK1

1.78e-0442954M39452
PathwaySA_PTEN_PATHWAY

AKT1 AKT2 MAPK1

1.88e-0417953M12771
PathwayBIOCARTA_MAL_PATHWAY

RAF1 LIMK1 MAPK1

2.25e-0418953MM1482
PathwaySIG_BCR_SIGNALING_PATHWAY

RAF1 AKT1 AKT2 MAPK1

2.54e-0446954M8626
PathwayWP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION

AKT1 AKT2 MAPK1

2.66e-0419953M39370
PathwayBIOCARTA_CCR3_PATHWAY

RAF1 LIMK1 MAPK1

2.66e-0419953MM1361
PathwayBIOCARTA_MAL_PATHWAY

RAF1 LIMK1 MAPK1

2.66e-0419953M10547
PathwayBIOCARTA_CCR3_PATHWAY

RAF1 LIMK1 MAPK1

2.66e-0419953M9152
PathwayWP_FOCAL_ADHESION

RAF1 CAPN1 LAMC1 LAMC3 AKT1 AKT2 MAPK1

2.67e-04187957MM15913
PathwayKEGG_PATHWAYS_IN_CANCER

RAF1 ZBTB16 LAMC1 LAMC3 WNT3A AKT1 AKT2 MMP2 MAPK1

3.40e-04325959M12868
PathwayWP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY

DDR2 AKT1 AKT2 MAPK1

3.52e-0450954M48087
PathwayWP_GNAQ_PATHWAYS_IN_PORTWINE_STAIN

RAF1 AKT1 MAPK1

3.61e-0421953M48342
PathwaySIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES

RAF1 AKT1 AKT2 MAPK1

3.80e-0451954M7955
PathwayKEGG_ENDOMETRIAL_CANCER

RAF1 AKT1 AKT2 MAPK1

4.09e-0452954M19877
PathwayBIOCARTA_IGF1R_PATHWAY

RAF1 AKT1 MAPK1

4.16e-0422953MM1438
PathwayKEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

4.43e-045952M48999
PathwayKEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS

RAF1 LIMK1 AKT1 AKT2 MAPK1

4.71e-0496955M16121
PathwayKEGG_NON_SMALL_CELL_LUNG_CANCER

RAF1 AKT1 AKT2 MAPK1

4.73e-0454954M19818
PathwayWP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR

AKT1 AKT2 MAPK1

4.76e-0423953MM15952
PathwayBIOCARTA_IGF1R_PATHWAY

RAF1 AKT1 MAPK1

4.76e-0423953M19613
PathwayWP_CARDIAC_HYPERTROPHIC_RESPONSE

RAF1 AKT1 AKT2 MAPK1

5.07e-0455954M39685
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

AKT1 AKT2 MAPK1

5.42e-0424953M27952
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

RAF1 WNT3A AKT1 AKT2 MAPK1

5.43e-0499955MM15905
PathwayWP_RELATIONSHIP_BETWEEN_INFLAMMATION_COX2_AND_EGFR

AKT1 AKT2 MAPK1

6.12e-0425953M39794
PathwayWP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION

AKT1 AKT2 MAPK1

6.12e-0425953M39384
PathwayWP_4HYDROXYTAMOXIFEN_DEXAMETHASONE_AND_RETINOIC_ACIDS_REGULATION_OF_P27_EXPRESSION

RAF1 AKT1 MAPK1

6.12e-0425953M39574
PathwayREACTOME_TRANSCRIPTIONAL_AND_POST_TRANSLATIONAL_REGULATION_OF_MITF_M_EXPRESSION_AND_ACTIVITY

EPRS1 WNT3A MAPK1

6.12e-0425953MM17240
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

RAF1 CAPN1 AKT1 AKT2 MAPK1

6.22e-04102955MM15830
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

RAF1 CAPN1 AKT1 AKT2 MAPK1

6.22e-04102955M39577
PathwayREACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY

RAF1 MAPK1

6.62e-046952M27559
PathwayREACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY

RAF1 MAPK1

6.62e-046952MM15273
PathwayKEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY

AKT1 AKT2

6.62e-046952M47523
PathwayWP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA

RAF1 AKT1 AKT2 MAPK1

6.63e-0459954M39750
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

DDR1 DDR2 LAMC1 LAMC3

6.63e-0459954M27218
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

RAF1 WNT3A AKT1 AKT2 MAPK1

6.79e-04104955M39625
PathwayBIOCARTA_RACCYCD_PATHWAY

RAF1 AKT1 MAPK1

6.89e-0426953M14512
PathwayWP_EPO_RECEPTOR_SIGNALING

RAF1 AKT1 MAPK1

6.89e-0426953M39687
PathwayWP_EPO_RECEPTOR_SIGNALING

RAF1 AKT1 MAPK1

6.89e-0426953MM15896
PathwayWP_GROWTH_FACTORS_AND_HORMONES_IN_BETA_CELL_PROLIFERATION

AKT1 AKT2 MAPK1

6.89e-0426953M48092
PathwayBIOCARTA_RACCYCD_PATHWAY

RAF1 AKT1 MAPK1

6.89e-0426953MM1423
PathwayWP_PLEURAL_MESOTHELIOMA

RAF1 LAMC1 LAMC3 NOTUM WNT3A AKT1 AKT2 MMP2 MAPK1 CDH13

7.36e-044399510M42563
PathwayWP_FOLLICLE_STIMULATING_HORMONE_FSH_SIGNALING

RAF1 AKT1 MAPK1

7.71e-0427953M39609
PathwayKEGG_COLORECTAL_CANCER

RAF1 AKT1 AKT2 MAPK1

8.01e-0462954M14631
PathwayWP_ENDOMETRIAL_CANCER

RAF1 AKT1 AKT2 MAPK1

8.51e-0463954M39623
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

RAF1 MAPK1

9.23e-047952MM17070
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

9.23e-047952M47407
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

9.23e-047952M47790
PathwayKEGG_GLIOMA

RAF1 AKT1 AKT2 MAPK1

9.57e-0465954M1835
PathwayWP_AGERAGE_PATHWAY

RAF1 AKT1 MMP2 MAPK1

1.01e-0366954M39420
PathwayREACTOME_LAMININ_INTERACTIONS

LAMC1 LAMC3 NID1

1.05e-0330953M27216
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

RAF1 WNT3A AKT1 AKT2 MAPK1

1.11e-03116955MM15863
PathwayWP_MELANOMA

RAF1 AKT1 AKT2 MAPK1

1.13e-0368954M39811
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

RAF1 WNT3A AKT1 AKT2 MAPK1

1.16e-03117955M39530
PathwayPID_AR_NONGENOMIC_PATHWAY

RAF1 AKT1 MAPK1

1.16e-0331953M213
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47399
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

RAF1 MAPK1

1.23e-038952M48010
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47394
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47395
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47404
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47405
PathwayKEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47803
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47715
PathwayREACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION

AKT1 AKT2

1.23e-038952M27806
PathwayKEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47482
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.23e-038952M47498
PathwayKEGG_RENAL_CELL_CARCINOMA

RAF1 AKT1 AKT2 MAPK1

1.26e-0370954M13266
PathwayKEGG_PANCREATIC_CANCER

RAF1 AKT1 AKT2 MAPK1

1.26e-0370954M9726
PathwayWP_IL17_SIGNALING

IL17RC AKT1 MAPK1

1.28e-0332953M39560
PathwayWP_REGUCALCIN_IN_PROXIMAL_TUBULE_EPITHELIAL_KIDNEY_CELLS

RAF1 AKT1 MAPK1

1.28e-0332953M39893
PathwayREACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING

AKT1 AKT2 MMP2 MAPK1

1.33e-0371954MM15590
PathwayKEGG_MELANOMA

RAF1 AKT1 AKT2 MAPK1

1.33e-0371954M15798
PathwayWP_RESISTIN_AS_A_REGULATOR_OF_INFLAMMATION

AKT1 AKT2 MAPK1

1.40e-0333953M39745
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMC1 AKT1 MAPK1

1.40e-0333953M39503
PathwayBIOCARTA_INTEGRIN_PATHWAY

RAF1 CAPN1 MAPK1

1.40e-0333953MM1426
PathwayWP_NONSMALL_CELL_LUNG_CANCER

RAF1 AKT1 AKT2 MAPK1

1.40e-0372954M39738
PathwayWP_CHROMOSOMAL_AND_MICROSATELLITE_INSTABILITY_IN_COLORECTAL_CANCER

RAF1 AKT1 AKT2 MAPK1

1.48e-0373954M39758
PathwayKEGG_CHRONIC_MYELOID_LEUKEMIA

RAF1 AKT1 AKT2 MAPK1

1.48e-0373954M321
PathwayBIOCARTA_INTEGRIN_PATHWAY

RAF1 CAPN1 MAPK1

1.52e-0334953M3342
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47397
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47392
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47391
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47402
PathwayKEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47802
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47490
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47481
PathwayKEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.57e-039952M47972
PathwayREACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING

AKT1 AKT2 MMP2 MAPK1

1.63e-0375954M27874
PathwayKEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY

RAF1 AKT1 AKT2 MAPK1

1.63e-0375954M5436
PathwayPID_PI3KCI_AKT_PATHWAY

RAF1 AKT1 AKT2

1.66e-0335953M249
PathwayKEGG_PRION_DISEASES

LAMC1 MAPK1 C8A

1.66e-0335953M13036
Pubmed

Wingless (Wnt)-3A induces trophoblast migration and matrix metalloproteinase-2 secretion through canonical Wnt signaling and protein kinase B/AKT activation.

WNT3A AKT1 MMP2

6.11e-083138319887570
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CALCOCO2 RAF1 DDR1 DPY19L1 ADCK1 DDR2 LIMK1 AP1B1 AP2B1 SH3PXD2A BUB1B AKT1 AKT2 EIF3B CDK11B MAPK1 PLEC

1.36e-079101381736736316
Pubmed

Discovery and refinement of loci associated with lipid levels.

RAF1 AOC1 TMEM176A LCAT LRP4 AKT1 PLEC KLHL8 DNAH11

1.83e-07211138924097068
Pubmed

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.

TGFBR3 AKT1 AKT2 MAPK1

2.30e-0714138412773577
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

RAF1 CAPN1 CPD AP1B1 AP2B1 DNAH17 MTMR2 AKT1 KDM2A AKT2 CDK11B MMP2 MAPK1 KLHL8 DNAH11

2.35e-077301381534857952
Pubmed

Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5/STK9) gene are associated with severe neurodevelopmental retardation.

CDKL2 CDKL1 CDKL5

2.44e-074138315499549
Pubmed

RAF1-MEK1-ERK/AKT axis may confer NSCLC cell lines resistance to erlotinib.

RAF1 AKT1 MAPK1

2.44e-074138323923067
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RAF1 RBM15 ZBTB16 NAA15 KIF26B WWP2 LAMC1 PARD3B STK32C WDR59 LIMK1 MDN1 SH3PXD2A BUB1B PLEC DOP1A

3.49e-078611381636931259
Pubmed

The protooncogene TCL1 is an Akt kinase coactivator.

TCL1B AKT1 AKT2

6.08e-075138310983986
Pubmed

Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo.

WNT3A AKT1 MAPK1

6.08e-075138319816934
Pubmed

Collagen I induces discoidin domain receptor (DDR) 1 expression through DDR2 and a JAK2-ERK1/2-mediated mechanism in primary human lung fibroblasts.

DDR1 DDR2 MAPK1

6.08e-075138321335558
Pubmed

Human chorionic gonadotropin stimulates trophoblast invasion through extracellularly regulated kinase and AKT signaling.

AKT1 MMP2 MAPK1

6.08e-075138318063683
Pubmed

Functional proteomics mapping of a human signaling pathway.

CALCOCO2 PAPPA2 ZBTB16 ERCC6 GLRX3 WWP2 LAMC1 AP1B1 YLPM1 NID1 KDM2A PLEC SDK1

7.35e-075911381315231748
Pubmed

DDR2 inhibition reduces migration and invasion of murine metastatic melanoma cells by suppressing MMP2/9 expression through ERK/NF-κB pathway.

DDR2 MMP2 MAPK1

1.21e-066138325733533
Pubmed

fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo.

AKT1 AKT2 MAPK1

1.21e-066138314749824
Pubmed

Simian immunodeficiency virus and human immunodeficiency virus type 1 matrix proteins specify different capabilities to modulate B cell growth.

AKT1 AKT2 MAPK1

1.21e-066138324623414
Pubmed

Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family.

TCL1B AKT1 AKT2

1.21e-066138311707444
Pubmed

Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity.

AKT1 AKT2 MAPK1

2.11e-067138328689659
Pubmed

Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation.

AKT1 AKT2 MAPK1

3.37e-068138320816796
Pubmed

Akt regulates vitamin D3-induced leukemia cell functional differentiation via Raf/MEK/ERK MAPK signaling.

RAF1 AKT1 MAPK1

3.37e-068138319058874
Pubmed

Involvement of extracellular signal-regulated kinase (ERK1/2)-p53-p21 axis in mediating neural stem/progenitor cell cycle arrest in co-morbid HIV-drug abuse exposure.

AKT1 AKT2 MAPK1

3.37e-068138324469921
Pubmed

HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2.

AKT1 AKT2 MAPK1

3.37e-068138322904195
Pubmed

PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung.

AKT1 AKT2 MAPK1

5.05e-069138315695173
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

DHX36 CACNA2D1 DPY19L1 GLRX3 DNAJC18 LAMC1 LAMC3 CPD MYORG TLL1 DHCR7 JMJD8 LRP4 NID1 MMP2 BACE2 CDH13

5.95e-0612011381735696571
Pubmed

Human polycystin-2 transgene dose-dependently rescues ADPKD phenotypes in Pkd2 mutant mice.

RAF1 AKT1 MAPK1

7.19e-0610138326435415
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPOUT1 ATP13A1 OBSCN SPATA20 LAMC3 STK32C WDR59 MYORG MDN1 ADAMTSL5 KLHL36 LRP4 PCNX1 AKT1 AKT2 PLEC

8.61e-0611051381635748872
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

SELL DPP4 CACNA2D1 ATP13A1 LAMC1 LCAT C8A CDH13

9.25e-06257138816335952
Pubmed

Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.

RAF1 AKT1 MAPK1

9.85e-0611138311435472
Pubmed

Opposite effects of HIV-1 p17 variants on PTEN activation and cell growth in B cells.

AKT1 AKT2 MAPK1

9.85e-0611138321423810
Pubmed

Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.

LAMC1 LAMC3 NID1

9.85e-0611138321084308
Pubmed

Critical roles for Akt kinase in controlling HIV envelope-mediated depletion of CD4 T cells.

AKT1 AKT2 MAPK1

9.85e-0611138323742646
Pubmed

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.

AKT1 AKT2

1.56e-052138227878243
Pubmed

ERK and RAF1 genes: analysis of methylation and expression profiles in patients with oral squamous cell carcinoma.

RAF1 MAPK1

1.56e-052138225265753
Pubmed

BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models.

AKT1 AKT2

1.56e-052138227699769
Pubmed

Altered AKT1 and MAPK1 gene expression on peripheral blood mononuclear cells and correlation with T-helper-transcription factors in systemic lupus erythematosus patients.

AKT1 MAPK1

1.56e-052138223125486
Pubmed

Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.

AKT1 AKT2

1.56e-052138231252679
Pubmed

Activation of Erk1/2 and Akt following unilateral ureteral obstruction.

AKT1 MAPK1

1.56e-052138218449171
Pubmed

Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.

AKT1 AKT2

1.56e-052138219622728
Pubmed

Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients.

AKT1 AKT2

1.56e-052138228271235
Pubmed

Discoidin domain receptor inhibition reduces neuropathology and attenuates inflammation in neurodegeneration models.

DDR1 DDR2

1.56e-052138228863860
Pubmed

Role of Akt in cardiac growth and metabolism.

AKT1 AKT2

1.56e-052138217019809
Pubmed

Discoidin domain receptor 2 is involved in the activation of bone marrow-derived dendritic cells caused by type I collagen.

DDR1 DDR2

1.56e-052138217113033
Pubmed

Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death.

AKT1 MAPK1

1.56e-052138210958679
Pubmed

Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo.

AKT1 AKT2

1.56e-052138233377281
Pubmed

Molecular cloning of complementary DNA encoding mouse seminal vesicle-secreted protein SVS I and demonstration of homology with copper amine oxidases.

AOC1 NID1

1.56e-052138212930721
Pubmed

Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin.

AKT1 AKT2

1.56e-05213829620559
Pubmed

Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts.

AKT1 AKT2

1.56e-052138211861503
Pubmed

Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation.

AKT1 AKT2

1.56e-052138212808085
Pubmed

Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes.

AKT1 AKT2

1.56e-052138215010337
Pubmed

Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.

AKT1 AKT2

1.56e-052138236229454
Pubmed

Akt2 regulates cardiac metabolism and cardiomyocyte survival.

AKT1 AKT2

1.56e-052138216950770
Pubmed

Akt isoforms differentially regulate neutrophil functions.

AKT1 AKT2

1.56e-052138220332370
Pubmed

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.

AKT1 AKT2

1.56e-05213823037531
Pubmed

High-intensity muscle contraction-mediated increases in Akt1 and Akt2 phosphorylation do not contribute to mTORC1 activation and muscle protein synthesis.

AKT1 AKT2

1.56e-052138232078465
Pubmed

Defining Akt actions in muscle differentiation.

AKT1 AKT2

1.56e-052138223076793
Pubmed

Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer.

AKT1 AKT2

1.56e-052138219110052
Pubmed

Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice.

AKT1 AKT2

1.56e-052138223919516
Pubmed

Cutaneous human papillomaviruses down-regulate AKT1, whereas AKT2 up-regulation and activation associates with tumors.

AKT1 AKT2

1.56e-052138217804734
Pubmed

Lack of AKT in adipocytes causes severe lipodystrophy.

AKT1 AKT2

1.56e-052138227408773
Pubmed

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.

AKT1 AKT2

1.56e-052138217141631
Pubmed

PI3K/AKT Signaling in Breast Cancer Molecular Subtyping and Lymph Node Involvement.

AKT1 AKT2

1.56e-052138231781306
Pubmed

Laminin gamma3 chain binds to nidogen and is located in murine basement membranes.

LAMC3 NID1

1.56e-052138215824114
Pubmed

Mutations in extracellular matrix genes NID1 and LAMC1 cause autosomal dominant Dandy-Walker malformation and occipital cephaloceles.

LAMC1 NID1

1.56e-052138223674478
Pubmed

Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.

AKT1 AKT2

1.56e-052138230692211
Pubmed

Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2.

DDR1 DDR2

1.56e-052138219900459
Pubmed

Discoidin domain receptors: a promoter of the aggressive behavior of ameloblastomas.

DDR1 DDR2

1.56e-052138224723326
Pubmed

Distinct actions of akt1 on skeletal architecture and function.

AKT1 AKT2

1.56e-052138224663486
Pubmed

Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway.

DPP4 MAPK1

1.56e-052138216611738
Pubmed

Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression.

AKT1 AKT2

1.56e-052138219491266
Pubmed

Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

AKT1 AKT2

1.56e-052138217609365
Pubmed

Identification of functional domains in AKT responsible for distinct roles of AKT isoforms in pressure-stimulated cancer cell adhesion.

AKT1 AKT2

1.56e-052138217825284
Pubmed

Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling.

WNT3A AKT1

1.56e-052138215994435
Pubmed

Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination.

AKT1 AKT2

1.56e-052138231847370
Pubmed

Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis.

AKT1 AKT2

1.56e-052138226654940
Pubmed

Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface.

LAMC1 NID1

1.56e-052138212931195
Pubmed

Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions.

AKT1 AKT2

1.56e-052138216923802
Pubmed

Discoidin domain receptors in disease.

DDR1 DDR2

1.56e-052138224361528
Pubmed

Role of AMPK and Akt in triple negative breast cancer lung colonization.

AKT1 AKT2

1.56e-052138233839456
Pubmed

Akt1 and Akt2: differentiating the aktion.

AKT1 AKT2

1.56e-052138221432781
Pubmed

Molecular alterations in AKT and its protein activation in human lung carcinomas.

AKT1 AKT2

1.56e-052138222748472
Pubmed

Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

AKT1 AKT2

1.56e-052138217045205
Pubmed

An extracellular matrix-specific microarray allowed the identification of target genes downstream of discoidin domain receptors.

DDR1 DDR2

1.56e-052138212935821
Pubmed

Analysis of nidogen-1/laminin γ1 interaction by cross-linking, mass spectrometry, and computational modeling reveals multiple binding modes.

LAMC1 NID1

1.56e-052138225387007
Pubmed

Activation of discoidin domain receptor 1 isoform b with collagen up-regulates chemokine production in human macrophages: role of p38 mitogen-activated protein kinase and NF-kappa B.

DDR1 MAPK1

1.56e-052138214764702
Pubmed

Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma.

DDR1 DDR2

1.56e-052138217299390
Pubmed

Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease.

AKT1 AKT2

1.56e-052138231671832
Pubmed

PKB signaling and atrogene expression in skeletal muscle of aged mice.

AKT1 AKT2

1.56e-052138221551011
Pubmed

Differential phosphorylation of Akt1 and Akt2 by protein kinase CK2 may account for isoform specific functions.

AKT1 AKT2

1.56e-052138224769357
Pubmed

Distinct and specific roles of AKT1 and AKT2 in androgen-sensitive and androgen-independent prostate cancer cells.

AKT1 AKT2

1.56e-052138223567263
Pubmed

Complex roles of discoidin domain receptor tyrosine kinases in cancer.

DDR1 DDR2

1.56e-052138233634432
Pubmed

Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C.

DDR1 DDR2

1.56e-05213827774938
Pubmed

Low stability and a conserved N-glycosylation site are associated with regulation of the discoidin domain receptor family by glucose via post-translational N-glycosylation.

DDR1 DDR2

1.56e-052138224018687
Pubmed

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition.

AKT1 AKT2

1.56e-052138216365168
Pubmed

Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.

RAF1 AKT1

1.56e-052138221881167
Pubmed

Prognostic significance of activated Akt expression in pancreatic ductal adenocarcinoma.

AKT1 AKT2

1.56e-052138215102693
Pubmed

AKT1 and AKT2 induce distinct phosphorylation patterns in HL-1 cardiac myocytes.

AKT1 AKT2

1.56e-052138225162660
Pubmed

Molecular cloning and characterization of mouse St7r (St7-like, St7l).

ST7 ST7L

1.56e-052138212060862
Pubmed

The Akt1 isoform is an essential mediator of ischaemic preconditioning.

AKT1 AKT2

1.56e-052138222117619
Pubmed

Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I.

DDR1 DDR2

1.56e-052138230458172
Pubmed

Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation.

AKT1 AKT2

1.56e-052138219142853
InteractionITGB3 interactions

RAF1 CAPN1 MDN1 AP1B1 NID1 AKT1 MMP2 PLEC TECPR1

2.34e-061701369int:ITGB3
Cytoband1q23-q25

SELL PAPPA2

5.36e-05413821q23-q25
GeneFamilyCyclin dependent kinases

CDKL2 CDKL1 CDKL5 CDK11B

7.55e-0626894496
GeneFamilyFerlin family

FER1L6 OTOF

3.55e-046892828
GeneFamilySPOUT methyltranferase domain containing

SPOUT1 MRM3

6.58e-0488921294
GeneFamilyWD repeat domain containing|BEACH domain containing

WDR81 WDFY4

8.43e-0498921230
GeneFamilyLaminin subunits

LAMC1 LAMC3

1.53e-0312892626
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

NOC2L TRPC5 WDR81 YLPM1 SMARCB1

2.00e-03181895694
GeneFamilyDyneins, axonemal

DNAH17 DNAH11

3.11e-0317892536
CoexpressionLEIN_MEDULLA_MARKERS

FNTA GLRX3 HLA-DRB5 CAPN1 SLC6A9 KLHL36

6.09e-06861376M1722
CoexpressionLEIN_MEDULLA_MARKERS

FNTA GLRX3 HLA-DRB5 CAPN1 SLC6A9 KLHL36

7.93e-06901376MM719
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 ZBTB16 DDR2 LAMC1 TGFBR3 PIEZO2 AEBP1 NID1 MMP2 SDK1

5.96e-1019613810bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

CACNA2D1 KIF26B DDR2 LAMC1 PIEZO2 AEBP1 NID1 MMP2 SDK1 CDH13

6.58e-1019813810df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA2 OBSCN WDR81 CHST1 PIEZO2 AEBP1 NID1 SDK1 CDH13

5.03e-091791389a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

ZBTB16 KIF26B LAMC1 PARD3B PIEZO2 NID1 MMP2 SDK1 CDH13

1.06e-081951389603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

CACNA2D1 KIF26B DDR2 LAMC1 PARD3B PIEZO2 AEBP1 MMP2 SDK1

1.16e-081971389fb847f2277609c31fffcdf49517243ce0684facf
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZBTB16 DDR2 LAMC1 TGFBR3 AEBP1 NID1 MMP2 SDK1

1.63e-071931388261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 DDR2 LAMC1 PI15 ADAMTSL5 AEBP1 NID1 MMP2

1.70e-0719413883d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAPPA2 DDR2 LAMC1 PI15 ADAMTSL5 AEBP1 NID1 MMP2

1.70e-071941388ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPP4 DDR2 LAMC1 CHST1 TGFBR3 ADAMTSL5 AEBP1 NID1

1.84e-071961388ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DDR2 LAMC1 PARD3B PIEZO2 AEBP1 NID1 SDK1 CDH13

1.84e-0719613887d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA2 TMEM176A LAMC1 CHST1 LRP4 MMP2 SDK1 CDH13

1.99e-071981388447d7182edb2cd8a72ebd3c0d16bc6e4ddcaaa5c
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

DDR2 LAMC1 TGFBR3 PIEZO2 AEBP1 NID1 SDK1 CDH13

1.99e-07198138826e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DDR2 LAMC1 PARD3B PIEZO2 AEBP1 NID1 SDK1 CDH13

1.99e-0719813888f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DDR2 TMEM176A LAMC1 PIEZO2 AEBP1 NID1 MMP2 CDH13

1.99e-071981388f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176A LAMC1 PIEZO2 AEBP1 LRP4 NID1 MMP2 CDH13

2.06e-07199138830ab0750d51f168b18c434c974d24a4e70f29cc7
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZBTB16 DDR2 LAMC1 TGFBR3 PIEZO2 AEBP1 NID1 MMP2

2.15e-072001388c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 SH3PXD2A YLPM1 PCNX1 BACE2 OAZ3 DOP1A

1.21e-061741387f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DDR2 LAMC3 PIEZO2 AEBP1 NID1 MMP2 CDH13

1.52e-061801387280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DDR2 LAMC3 PIEZO2 AEBP1 NID1 MMP2 CDH13

1.52e-061801387fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDR2 TGFBR3 AEBP1 LRP4 NID1 TRPV3 MMP2

1.70e-06183138706a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176A LAMC1 CHST1 LRP4 MMP2 SDK1 CDH13

1.89e-061861387360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 DDR2 PI15 AEBP1 NID1 EML1 MMP2

2.10e-061891387544d95df910f1b276995624509a7e41b219baca0
ToppCellfacs-BAT-Fat-18m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 DDR2 LAMC1 LAMC3 AEBP1 NID1 MMP2

2.10e-061891387bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 DDR2 LAMC1 LAMC3 AEBP1 NID1 MMP2

2.10e-061891387cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCellmoderate-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CACNA2D1 LAMC1 PI15 AEBP1 NID1 MMP2 CDH13

2.10e-06189138722a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 DDR2 LAMC1 LAMC3 AEBP1 NID1 MMP2

2.10e-06189138787323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA2D1 DDR2 LAMC1 LAMC3 MDN1 AEBP1 NID1

2.18e-0619013871121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA2D1 DDR2 LAMC1 LAMC3 MDN1 AEBP1 NID1

2.18e-061901387048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

CACNA2D1 DDR2 PIEZO2 AEBP1 NID1 SDK1 CDH13

2.18e-0619013873a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LAMC3 CHST1 TBCCD1 SHROOM1 AEBP1 EML1 MMP2

2.18e-06190138739fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 CHST1 PIEZO2 SCCPDH ADAMTSL5 LRP4 DNAH11

2.26e-061911387df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

DDR2 TMEM176A LAMC3 PIEZO2 AEBP1 MMP2 CDH13

2.26e-061911387e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

DDR2 TMEM176A LAMC3 PIEZO2 AEBP1 MMP2 CDH13

2.26e-0619113871726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZBTB16 LAMC1 PARD3B PIEZO2 NID1 SDK1 CDH13

2.26e-0619113876688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPP4 DDR2 LAMC1 CHST1 ADAMTSL5 AEBP1 NID1

2.34e-06192138730cefa0990ba1f379f350bfbf994a78db145075e
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZBTB16 LAMC1 PARD3B PIEZO2 NID1 SDK1 CDH13

2.34e-06192138799ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF26B DDR2 PIEZO2 AEBP1 NID1 MMP2 SDK1

2.34e-061921387162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR2 LAMC1 PI15 AEBP1 NID1 MMP2 BACE2

2.42e-061931387858a186804b36d45957238d3d3eed2768b961641
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR2 LAMC1 PI15 AEBP1 NID1 MMP2 BACE2

2.42e-0619313877865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZBTB16 DDR2 LAMC1 PARD3B PIEZO2 NID1 SDK1

2.42e-061931387b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DDR2 TMEM176A AEBP1 LRP4 NID1 MMP2 CDH13

2.42e-061931387084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 ZBTB16 LAMC1 TGFBR3 PIEZO2 NID1 SDK1

2.50e-061941387e93de9428c986b8943fc169258847c650cfab0e5
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPP4 DDR2 CHST1 PI15 ADAMTSL5 AEBP1 NID1

2.50e-0619413877b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176A LAMC1 CHST1 LRP4 MMP2 SDK1 CDH13

2.50e-061941387735eee6ef25589f935fa922788ebbdbfef61249e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B DDR2 LAMC3 PIEZO2 AEBP1 NID1 MMP2

2.50e-061941387240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B DDR2 LAMC3 PIEZO2 AEBP1 NID1 MMP2

2.50e-061941387ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDR2 LAMC1 TGFBR3 PIEZO2 AEBP1 NID1 MMP2

2.59e-061951387f54bc4454270ff06e85596f98199372b50d0179f
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAPPA2 DDR2 PI15 TGFBR3 AEBP1 NID1 MMP2

2.59e-0619513870feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

DDR2 LAMC1 PIEZO2 AEBP1 NID1 SDK1 CDH13

2.59e-06195138761c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAPPA2 DDR2 PI15 TGFBR3 AEBP1 NID1 MMP2

2.59e-0619513872a6f67875cef140b0e6b8401436719675c6b3665
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B DDR2 LAMC3 PIEZO2 AEBP1 NID1 MMP2

2.59e-06195138744d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR2 PI15 PIEZO2 AEBP1 LRP4 NID1 MMP2

2.68e-0619613876bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 DDR2 LAMC1 FBXO30 TGFBR3 AKT2 MMP2

2.68e-06196138766d76249bd2770cdddff2c1fe59a016e95da2124
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR2 PI15 PIEZO2 AEBP1 LRP4 NID1 MMP2

2.68e-061961387c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176A LAMC1 CHST1 LRP4 MMP2 SDK1 CDH13

2.68e-0619613871f47916c2663bd88c1e7c19c6a7688f4c7173ad2
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 DDR2 LAMC1 FBXO30 TGFBR3 AKT2 MMP2

2.68e-0619613879bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 DDR2 LAMC1 TGFBR3 AEBP1 NID1 MMP2

2.68e-061961387b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 DDR2 LAMC1 TGFBR3 AEBP1 NID1 MMP2

2.68e-061961387787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLBD1 TMEM176A LAMC1 LRP4 MMP2 SDK1 CDH13

2.68e-0619613871bcae4e0a244af822e2b12b2026a2771316f107d
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA2D1 KIF26B DDR2 PIEZO2 AEBP1 MMP2 SDK1

2.77e-061971387f1c8936986123a3151140c374fcd62d6705c530b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176A LAMC1 LRP4 NID1 MMP2 SDK1 CDH13

2.77e-0619713871da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176A LAMC1 CHST1 AEBP1 MMP2 SDK1 CDH13

2.77e-06197138769fde2d27881f8408216e231c71cfdbd96f28d45
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 GLRX3 DDR2 LAMC1 PI15 NID1 MMP2

2.86e-0619813875e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIF26B DDR2 LAMC1 PIEZO2 AEBP1 MMP2 SDK1

2.86e-0619813873ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176A LAMC1 LRP4 NID1 MMP2 SDK1 CDH13

2.86e-0619813874a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

CACNA2D1 DDR2 PIEZO2 AEBP1 NID1 MMP2 SDK1

2.96e-0619913874bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DDR2 LAMC1 PIEZO2 AEBP1 NID1 MMP2 CDH13

2.96e-06199138766a79732caf2f04c09b4d9832377aa01ca477677
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

DDR2 TMEM176A LAMC1 PIEZO2 AEBP1 MMP2 CDH13

2.96e-061991387f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

DDR2 TMEM176A LAMC1 PIEZO2 AEBP1 MMP2 CDH13

2.96e-0619913879c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellcellseq-Mesenchymal-Fibroblastic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DDR2 LAMC1 PIEZO2 AEBP1 NID1 MMP2 CDH13

3.06e-0620013878978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial|6m / Sample Type, Dataset, Time_group, and Cell type.

DDR2 LAMC1 PI15 TGFBR3 PIEZO2 NID1 MMP2

3.06e-0620013872cc98abf11f5b58707de45a2282f03d47f00f035
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DDR2 TGFBR3 PIEZO2 AEBP1 NID1 MMP2 SDK1

3.06e-062001387389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell3'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB16 DDR2 LAMC1 TGFBR3 AEBP1 NID1 MMP2

3.06e-06200138787177c973e722ac7d9ee503b9cfacd84fc67865d
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DDR2 TGFBR3 PIEZO2 AEBP1 NID1 MMP2 SDK1

3.06e-062001387cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

DDR2 LAMC1 PI15 TGFBR3 PIEZO2 NID1 MMP2

3.06e-0620013870f7431f670f3a175377cefae3479403a881bb8fb
ToppCell5'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB16 DDR2 LAMC1 TGFBR3 AEBP1 NID1 MMP2

3.06e-0620013875a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KIF26B CHST1 CDKL1 PIEZO2 KLHL8 DOP1A

5.42e-0614213867b6678a73d04feac12bbc909f2df478215511de0
ToppCellMild/Remission-B_naive-13|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DPP4 OTOF NOTUM HYLS1 BACE2 TDRD12

5.42e-06142138649873a2d9b1ae4bdbf253d1c09bf8845cc0cc917
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KIF26B CHST1 CDKL1 PIEZO2 KLHL8 DOP1A

5.42e-061421386347f5832a86f4e41752e36e3e737df7ca6f79e90
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC3 CDKL1 LRP4 MMP2 SDK1 CDH13

1.07e-0516013866215ac6123a295f3c2f033786602a57b2e2e1177
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CALCOCO2 CACNA2D1 ZBTB16 TGFBR3 AEBP1 NID1

1.32e-05166138694636dbc039f794c735960c3425e00bdd5523602
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

OBSCN TMEM176A LAMC3 AEBP1 LRP4 MMP2

1.42e-051681386d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDKL2 KIF26B SCCPDH DNAH17 AKT2 DNAH11

1.52e-0517013865d5f208682be21ed58320f5fc083a7898f8712da
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

CACNA2D1 DDR2 OBSCN LAMC3 PI15 NID1

1.57e-051711386080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDR2 LAMC1 TGFBR3 AEBP1 NID1 MMP2

1.62e-051721386e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DDR2 TGFBR3 PIEZO2 TLL1 NID1 BACE2

1.67e-051731386a81992965137195d20fc498f750975303961a828
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDKL2 FBXO30 MRM3 ADAMTSL5 AEBP1 CDH13

1.73e-0517413869f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLBD1 CWF19L2 DPY19L1 DNAJC18 MDN1 TRIM36

1.79e-051751386bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CACNA2D1 LAMC3 PI15 AEBP1 NID1 CDH13

1.79e-051751386f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

ZBTB16 DDR2 LAMC1 TGFBR3 NID1 MMP2

2.03e-051791386dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR2 CHST1 PI15 AEBP1 NID1 MMP2

2.09e-051801386f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 DPY19L1 PARD3B TGFBR3 NID1 BACE2

2.16e-051811386fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DDR2 LAMC3 TGFBR3 NOTUM AEBP1 MMP2

2.23e-051821386812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DDR2 LAMC1 TGFBR3 AEBP1 NID1 MMP2

2.44e-0518513869faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA2D1 DDR2 PARD3B TGFBR3 MMP2 SDK1

2.44e-051851386a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellmoderate-Lymphoid-NK|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CACNA2D1 PI15 AEBP1 NID1 MMP2 CDH13

2.44e-0518513864979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

KIF26B PARD3B NOTUM SH3PXD2A LRP4 SDK1

2.52e-051861386de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

KIF26B PARD3B NOTUM SH3PXD2A LRP4 SDK1

2.52e-0518613860b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA2D1 LAMC1 PIEZO2 AEBP1 SDK1 CDH13

2.59e-051871386e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell3'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB16 LAMC1 TGFBR3 AEBP1 NID1 MMP2

2.59e-051871386f0c4d93f75615e570e4465fd622e3124189618a1
Drug3-(phenylsulfonyl)-4-(2-(4-(2-(3,7,11-trimethyldodeca-2,6,10-trienylthio)benzoyl)piperazin-1-yl)ethoxy)-1,2,5-oxadiazole-2-oxide

RAF1 AKT1 MAPK1

8.49e-0741373ctd:C559860
DrugExcitatory Amino Acid Agonists

CAPN1 LIMK1 AKT1 MMP2 MAPK1

1.52e-06331375ctd:D018690
Drugfarnesylthiosalicylic acid

RAF1 AKT1 MMP2 MAPK1

1.63e-06151374ctd:C093323
Drugmethanandamide

RAF1 AKT1 MMP2 MAPK1

6.93e-06211374ctd:C088155
Drugchaetoglobosins

RAF1 AKT1 MAPK1

7.33e-0671373ctd:C019290
DrugN-vinyl-2-pyrrolidinone

DDR1 CAPN1 AKT1 AKT2

1.69e-05261374ctd:C042670
DrugYM 529

AKT1 MMP2 MAPK1

1.74e-0591373ctd:C087958
Drugtriciribine

AKT1 AKT2 MMP2

2.48e-05101373ctd:C023764
Drug4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline

CAPN1 AKT1 MMP2 MAPK1

2.65e-05291374ctd:C568862
DrugAC1O0B8G

RAF1 LAMC1 LAMC3 BUB1B AKT1 MMP2 MAPK1 BACE2 CDH13

3.07e-052621379CID000091605
Drug2-aminoethoxydiphenyl borate

CAPN1 TRPC5 AKT1 TRPV3 MAPK1

3.33e-05611375ctd:C109986
Drugparthenin

RAF1 AKT1 MAPK1

3.39e-05111373ctd:C022097
Diseaseprostate adenocarcinoma (is_implicated_in)

RAF1 AKT1 AKT2 MAPK1

1.98e-06201364DOID:2526 (is_implicated_in)
DiseaseColorectal Carcinoma

CALCOCO2 ERCC6 RBM10 ETFDH OBSCN LAMC1 STK32C FBXO30 CDKL5 BUB1B NID1 AKT1 KDM2A MMP2

4.81e-0670213614C0009402
Diseaseautism spectrum disorder (implicated_via_orthology)

GABRB3 NAA15 DSCAM TRPC5 LAMC1 LAMC3 MAPK1

7.02e-061521367DOID:0060041 (implicated_via_orthology)
Diseasecolorectal cancer (is_implicated_in)

ERCC6 RBM10 DDR2 BUB1B AKT1 TRPV3

2.14e-051211366DOID:9256 (is_implicated_in)
Diseasecorpus callosum volume measurement

CACNA2D1 KIF26B LAMC1 EML1 PLEC

1.02e-041001365EFO_0010299
DiseaseAngelman Syndrome

GABRB3 CDKL5

1.26e-0441362C0162635
DiseaseDupuytren Contracture

ST7 DDR2 ATE1 CDKL1 SDK1

1.47e-041081365EFO_0004229
DiseaseMyasthenic Syndromes, Congenital

ALG2 LRP4 PLEC

1.81e-04241363C0751882
Diseaseosteoarthritis, knee, total joint arthroplasty

AOC1 TMEM176A

2.09e-0451362EFO_0004616, EFO_0010726
Diseasemyocardial infarction (implicated_via_orthology)

LCAT AKT1 MMP2 MAPK1

2.49e-04661364DOID:5844 (implicated_via_orthology)
Diseasecolorectal adenocarcinoma (is_marker_for)

RAF1 ERCC6 SMARCB1

2.58e-04271363DOID:0050861 (is_marker_for)
Diseaseresponse to gases and fumes exposure, forced expiratory volume

AOC1 TMEM176A

3.13e-0461362EFO_0004314, EFO_0006994
DiseaseAortic Diseases

LAMC1 MMP2

3.13e-0461362C0003493
DiseaseNeoplasm of uncertain or unknown behavior of ovary

ERCC6 AKT1 AKT2

3.21e-04291363C0496920
DiseaseOvarian Carcinoma

ERCC6 AKT1 AKT2

3.55e-04301363C0029925
Diseaseright ventricular ejection fraction measurement

OBSCN DNAJC18 PLEC

3.55e-04301363EFO_0021816
Diseasecentral nervous system cancer

PAPPA2 ZBTB16 PIEZO2

3.92e-04311363EFO_0000326
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

FER1L6 OTOF

4.36e-0471362DOID:11724 (implicated_via_orthology)
Diseasegestational age

ZBTB16 TGFBR3 WNT3A PCNX1 SDK1

4.59e-041381365EFO_0005112
Diseasehippocampal volume

DPP4 ETFDH PARD3B EML1 PLEC CDH13 DNAH11

4.71e-042971367EFO_0005035
Diseaseascending aortic diameter

WWP2 PI15 LIMK1 PIEZO2 CDH13

4.90e-041401365EFO_0021787
Disease2-hydroxyphenylacetate measurement

CFAP251 SPOUT1

5.80e-0481362EFO_0800131
DiseaseMarfan Syndrome, Type I

LAMC1 MMP2

7.43e-0491362C4721845
DiseaseNon-Small Cell Lung Carcinoma

RAF1 PLBD1 AKT1 AKT2 CDH13

7.99e-041561365C0007131
Diseasecolorectal cancer (is_marker_for)

DDR1 ERCC6 AKT1 AKT2 MMP2

8.22e-041571365DOID:9256 (is_marker_for)
Diseaseleft ventricular ejection fraction measurement

DNAJC18 SMARCB1 PLEC

8.35e-04401363EFO_0008373
Diseasehypertrophic cardiomyopathy

DNAJC18 PARD3B CHST1 SMARCB1

8.81e-04921364EFO_0000538
DiseaseNeurodevelopmental Disorders

GABRB3 DSCAM PARD3B CDKL5

9.18e-04931364C1535926
DiseaseAlzheimer disease, educational attainment

DPP4 HLA-DRB5 LAMC1 MTMR2 BACE2 TRIM36

1.03e-032471366EFO_0011015, MONDO_0004975
Diseaseleft ventricular systolic function measurement

OBSCN DNAJC18 SMARCB1

1.10e-03441363EFO_0008206
Diseaseaortic measurement

WWP2 HLA-DRB5 PI15 LIMK1 TLL1 CDH13

1.12e-032511366EFO_0020865
DiseaseMarfan Syndrome

LAMC1 MMP2

1.13e-03111362C0024796
Diseaseendometrial adenocarcinoma (is_marker_for)

TGFBR3 MAPK1

1.13e-03111362DOID:2870 (is_marker_for)
Diseasesevere acute respiratory syndrome, COVID-19

CACNA2D1 TST WDFY4 GRAMD4 TGFBR3 MTMR2 CDK11B CDH13

1.13e-034471368EFO_0000694, MONDO_0100096
Diseasespontaneous preterm birth

GABRB3 DSCAM STK32C SDK1

1.25e-031011364EFO_0006917
DiseaseLung Neoplasms

RAF1 DDR1 ERCC6 AKT1 MAPK1 CDH13

1.47e-032651366C0024121
DiseaseMalignant neoplasm of lung

RAF1 DDR1 ERCC6 AKT1 MAPK1 CDH13

1.50e-032661366C0242379
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRB3 NAA15 PARD3B

1.51e-03491363DOID:0060037 (implicated_via_orthology)
Diseaseskin melanoma (is_marker_for)

DDR1 MMP2

1.59e-03131362DOID:8923 (is_marker_for)
DiseaseMetabolic Bone Disorder

DHCR7 MMP2

1.85e-03141362C0005944
Diseaseabdominal aortic aneurysm (biomarker_via_orthology)

SELL MMP2

1.85e-03141362DOID:7693 (biomarker_via_orthology)
DiseaseKartagener syndrome (implicated_via_orthology)

AP1B1 DNAH11

1.85e-03141362DOID:0050144 (implicated_via_orthology)
DiseaseUveal Melanoma

CACNA2D1 AP2B1 TRIM36

1.90e-03531363EFO_1000616
Diseasecortical thickness

DPP4 ZBTB16 LAMC1 LAMC3 SH3PXD2A WNT3A YLPM1 MTMR2 LRP4 EML1 PLEC KLHL8 TRIM36

1.95e-03111313613EFO_0004840
Diseaseocular sarcoidosis

KIF26B PARD3B STK32C GRAMD4

2.07e-031161364EFO_0010723
DiseaseDown syndrome (implicated_via_orthology)

DSCAM DOP1A

2.13e-03151362DOID:14250 (implicated_via_orthology)
DiseaseOsteopenia

DHCR7 MMP2

2.13e-03151362C0029453
Diseaseneuropsychological test

GABRB3 ACSS1 CDKL1 FER1L6 CDH13

2.24e-031971365EFO_0003926
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

ALG2 LRP4

2.43e-03161362C0751885
Diseaseendometriosis (biomarker_via_orthology)

SELL MMP2

2.43e-03161362DOID:289 (biomarker_via_orthology)
Diseasenervousness

ETFDH YLPM1

2.43e-03161362NCIT_C74532
Diseaseurate measurement, spine bone mineral density

PAPPA2 CACNA2D1 CDH13

2.46e-03581363EFO_0004531, EFO_0007701
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

ALG2 LRP4

2.74e-03171362C0751883
Diseaseerythritol measurement

CACNA2D1 DDR2

2.74e-03171362EFO_0021171
Diseasefish consumption measurement

EML1 SDK1 CDH13

3.25e-03641363EFO_0010139
Diseaseelectrocardiography

RAF1 DDR2 OBSCN SH3PXD2A SMARCB1 PCNX1 PLEC CDH13

3.26e-035301368EFO_0004327
DiseaseCongenital Myasthenic Syndromes, Presynaptic

ALG2 LRP4

3.43e-03191362C0751884
DiseaseMeningioma

SMARCB1 AKT1

3.43e-03191362C0025286
Diseasediet measurement

GABRB3 DSCAM DPY19L1 KIF26B ACSS1 TEX15 RANBP17 TLL1 MTMR2 UBR3 SDK1 CDH13

3.43e-03104913612EFO_0008111
Diseaseovarian neoplasm

ERCC6 AKT1 AKT2 MAPK1

3.49e-031341364C0919267
DiseaseMalignant neoplasm of ovary

ERCC6 AKT1 AKT2 MAPK1

3.78e-031371364C1140680
Diseaseacetate measurement

ACSS1 SPG11

3.79e-03201362EFO_0010112
Diseaselung non-small cell carcinoma (is_implicated_in)

DDR1 ERCC6 KDM2A CDH13

3.98e-031391364DOID:3908 (is_implicated_in)
Diseasebrain measurement, neuroimaging measurement

DPP4 KIF26B LAMC1 ST7L SH3PXD2A EML1 PLEC DNAH11

4.07e-035501368EFO_0004346, EFO_0004464
Diseasemetabolite measurement

CFAP251 AOC1 DSCAM NAT16 DDR2 ETFDH WDFY4 YLPM1

4.53e-035601368EFO_0004725
DiseaseNasopharyngeal carcinoma

AKT2 MMP2

4.59e-03221362C2931822

Protein segments in the cluster

PeptideGeneStartEntry
GEKRYYSDPRFLNLW

BUB1B

111

O60566
GEYIKTWRPRYFLLK

AKT1

16

P31749
GEYIKTWRPRYFLLK

AKT2

16

P31751
YEEYIRPLLQSWRSK

ACOX2

666

Q99424
PWSYFPKISIYLRDE

BACE2

351

Q9Y5Z0
YPNAGRYWETVERLK

ACSS1

366

Q9NUB1
PYGSEEYLQLRSKSW

ADCK1

61

Q86TW2
TETYVRWSPKGTYLA

EIF3B

336

P55884
DRGYIYWRLLSTDPV

AP2B1

521

P63010
ITYRSWGRSLKYNPV

C8A

441

P07357
DYWRILNPGEYRVTA

AEBP1

941

Q8IUX7
YVWIEGTKDPSRNRY

ATP13A1

461

Q9HD20
FRKSQELRVWPGYDY

DDR1

241

Q08345
RLRAKYDTPYIIWRS

GRAMD4

381

Q6IC98
YRTKLRGPSYIWTFR

DNAH11

4481

Q96DT5
QYKYETGLSDSRPLW

DOP1A

1696

Q5JWR5
DRGYIYWRLLSTDPV

AP1B1

521

Q10567
LWYRAPELLLGAKEY

CDK11B

601

P21127
TWARYPLAVTKYRES

AOC1

616

P19801
TIRYSVYKDPAGWLN

CDH13

511

P55290
VTEWYELRKAPSDLY

CAPN1

221

P07384
GRDWERYTAAVPYRL

DHCR7

456

Q9UBM7
PEDLWVSYLGRVYDL

CYB5D1

31

Q6P9G0
GWNSSLPVYYIREER

CFAP251

256

Q8TBY9
WIYSASTLERGYPKP

MMP2

541

P08253
YYIGKERRTWEESLL

KLRC1

131

P26715
RPRGQRDSSYYWEIE

RAF1

331

P04049
VTNLKYWGRYEPVIS

RANBP17

596

Q9H2T7
LYWDGERRTYVPALE

RBM10

606

P98175
IRTIDYRKGDSWAYI

RBM15

481

Q96T37
SWDYTKPYLGRRDRG

HNRNPLL

256

Q8WVV9
PWSAVRVKEYGYTRL

ACP7

386

Q6ZNF0
YRASIRGKKWYSSPL

ERCC6

941

P0DP91
RYYWERERKPKTEEF

OVOS1

956

Q6IE37
RWYRAPEIMLNSKGY

MAPK1

191

P28482
LQRYLKTREKGPGYW

PARD3B

31

Q8TEW8
SRPYKISESSKVYRW

KLHL36

11

Q8N4N3
RYRLAEPTEKEYDWL

MDN1

1281

Q9NU22
IKRGKTRNYLYPIWS

OAZ3

16

Q9UMX2
YRAVTELGRPDAEYW

HLA-DRB5

76

Q30154
PMYKINYSRDGTRWI

DDR2

116

Q16832
EVRQGLKAYSSWPTY

GLRX3

186

O76003
SPESWYRKAYEESRA

KIF26B

36

Q2KJY2
ITSYVRPVKFWERDY

PCNX1

1511

Q96RV3
RYDPRSNKWDYVAAL

KLHL8

526

Q9P2G9
GLDYLPSRYHSWLRD

NAT16

76

Q8N8M0
RDGASPSRIYTYQWR

NID1

596

P14543
DYRRERWRKPTYSDK

CWF19L2

281

Q2TBE0
YYILEESWCVRRSKP

DPY19L1

611

Q2PZI1
PFSRSYYWIGIRKIG

SELL

81

P14151
WKLYDPLLEYRRQGI

MTMR2

206

Q13614
PSYRITWTGKEDIIY

DPP4

181

P27487
YWRDKRLAYSGIPLN

GABRB3

91

P28472
EGTPLTLYYSHWRKL

NOC2L

611

Q9Y3T9
VYKNRSPLRAREYVW

ADAMTSL5

406

Q6ZMM2
RLKIYEEAWTKYPRG

NAA15

276

Q9BXJ9
YSEQTDVLRKGYWPS

PLBD1

386

Q6P4A8
YPQIRWYKDGALLTT

OBSCN

6136

Q5VST9
PAGYYLKESRGSRRW

NOTUM

106

Q6P988
IYTPKGYLDQWATRA

PAPPA2

1181

Q9BXP8
WYRAPELLVGDVKYG

CDKL2

166

Q92772
YTIYPRDKDKRWEGV

ETFDH

46

Q16134
YFEYKRDWDSIRLPG

HYLS1

216

Q96M11
WTRYYETPEEEREKL

KDM2A

126

Q9Y2K7
RADTLSLPWKDYVIY

DNAH17

851

Q9UFH2
YDVRRRPWYIQGAAS

CACNA2D1

236

P54289
DYVATRWYRSPELLV

CDKL1

161

Q00532
RWYRSPELLVGDTQY

CDKL1

166

Q00532
PGTRRYWIKETDSEY

C7orf57

56

Q8NEG2
RKGSPVAYSLPDWYI

C7orf57

91

Q8NEG2
EAIYKERWPDYVREL

DHX36

436

Q9H2U1
HPVTTYKTGDYWRLL

CPD

821

O75976
KPAEPWYKETTYRRD

C1orf100

86

Q5SVJ3
IGIFRVGWKTTREYY

CALCOCO2

56

Q13137
VYDGSLIDWLPYSRI

MBLAC2

191

Q68D91
LIDWLPYSRISDYVG

MBLAC2

196

Q68D91
IDRGWRRSGKYVYKP

ATE1

51

O95260
WTEAYIDAVRRNKYP

DNAJC18

11

Q9H819
YRLLRYSPVKDAWDE

KLHDC7B

461

Q96G42
GYVRDETVRAAPYDW

LCAT

156

P04180
AIYKRTREDGPWIPY

LAMC1

161

P11047
FDSVRQRLPKYYSWE

KRBOX4

136

Q5JUW0
LPTKRLKLEWVYGYR

EML1

216

O00423
RWPVSYADRKSYENL

FBXO30

96

Q8TB52
YVATRWYRSPELLLG

CDKL5

171

O76039
PESVGYRIKYWRSDL

SDK1

1206

Q7Z5N4
DPRTKAGLYWGYTVR

SPOUT1

251

Q5T280
EVRIWSYTQPRYEKE

IL17RC

241

Q8NAC3
WARFYVKIYRAEGLP

OTOF

416

Q9HC10
LRWYLATGEEIYDVP

DSCAM

56

O60469
PWARFYVRLYKAEGL

FER1L6

241

Q2WGJ9
REAWATKGPSYEDLY

GTF2E1

236

P29083
WAFRVEPYSYLVKVG

TRIM36

576

Q9NQ86
EALGIRKPYIWEYSR

EPRS1

411

P07814
DKLLWQDSRYRPLYP

MRPL4

271

Q9BYD3
PCTYYLEPKRRWVTG

SNAP47

56

Q5SQN1
YIEVRDGYWRKSPLL

TLL1

406

O43897
YEKRGGTYWALLRTL

TMEM176A

106

Q96HP8
RRWPISYCRELKGYS

SCCPDH

231

Q8NBX0
TWEESGLRYDKAYPG

MRM3

86

Q9HC36
SVYWPAKRGITIYAD

TDRD12

326

Q587J7
PSYVLYRDRAEWADI

FNTA

61

P49354
GTDLLPYLDWDYVRV

SHROOM1

51

Q2M3G4
GSLYKRYPSLWRRLA

SMARCB1

41

Q12824
SATSVYWYRERPGEV

TRGV9

51

Q99603
AEYNRYTWVTGREPL

ST7

146

Q9NRC1
YELLRGWRPYDIHSS

STK32C

286

Q86UX6
LKRLYRAPIDWIEEY

ALG2

151

Q9H553
LWYGTGRKPYNLDVT

CHST1

256

O43916
TTYKDQPYLWARLDR

C12orf29

66

Q8N999
AVRYLKPDVTQTWRY

TEPP

216

Q6URK8
KSYSPEALWRYLTAR

SPG11

876

Q96JI7
WEKRTDPRGRFYYVD

WWP2

336

O00308
EIPPDWRIEKTYLYL

ZBTB16

656

Q05516
VEGLRRLSDYPEYMW

AGPAT3

156

Q9NRZ7
KPGVYTRVTSYRNWI

TMPRSS11B

396

Q86T26
IRYLGKEGWAPASYL

SH3PXD2A

306

Q5TCZ1
RGQRPKEGAYYVWTV

SPATA20

391

Q8TB22
YRRYKSRDIWAKIPS

TECPR1

166

Q7Z6L1
AGSRWPELYLYSRAD

TMEM53

206

Q6P2H8
RSLWYATHYPTDERK

PIEZO2

386

Q9H5I5
FVDVYGYIATPRVWK

WDFY4

1211

Q6ZS81
RTSPSEEYWRLYVLK

SLC6A9

261

P48067
EYRRYTWVTGKEPLT

ST7L

166

Q8TDW4
LRYYRESADPLGAWL

PLEC

1346

Q15149
AVWQLYPGRKYRAAD

TCL1B

86

O95988
YPERGDTWREKRDYV

YLPM1

1376

P49750
YGEILYRWGLREKRA

WDR59

866

Q6PJI9
RLYSIDSEYNPWRKL

UBR3

1496

Q6ZT12
GWVETLRPRYTYFKV

WNT3A

251

P56704
RSLSRKFTDWAYGPV

TRPV3

371

Q8NET8
AYVKYNGSRPREEWE

TRPC5

456

Q9UL62
RYRSILQLVKPWYDE

PI15

131

O43692
QIRATEGAYPRLYWS

TBCCD1

41

Q9NVR7
WYDETLYAELLGKPR

TEX15

1721

Q9BXT5
WYSPGTREARKEYLE

TST

36

Q16762
GSKDRTVRLWPLYNY

WDR81

1666

Q562E7
GTRPRWSALDGVVYY

TGFBR3

506

Q03167
DYRYTGSDVWTPIEK

ZNF541

1156

Q9H0D2
TSDRLYWYRQDPGKS

TRAV39

46

A0A0B4J263
SEVIYGRKRWFLYPP

JMJD8

186

Q96S16
AIYKRSRADGPWEPY

LAMC3

146

Q9Y6N6
WPNGLTLDYDTRRIY

LRP4

1516

O75096
PDRKKRYTVVGNPYW

LIMK1

501

P53667
QERDVYLPAGKWRSY

MYORG

671

Q6NSJ0