Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H4K20 demethylase activity

KDM7A PHF8

5.85e-054632GO:0035575
GeneOntologyMolecularFunctionhistone H4 demethylase activity

KDM7A PHF8

9.74e-055632GO:0141058
GeneOntologyMolecularFunctionhistone H3K27me2/H3K27me3 demethylase activity

KDM7A PHF8

9.74e-055632GO:0071558
GeneOntologyMolecularFunctionhistone H3K9me/H3K9me2 demethylase activity

KDM7A PHF8

9.74e-055632GO:0140683
GeneOntologyMolecularFunctionactin binding

FLNB FLNC MYLK PDLIM1 PRKN PLEC TNNI1 EPB41L1

1.26e-04479638GO:0003779
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2B KMT2A

2.71e-048632GO:0140945
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2B KMT2A

4.34e-0410632GO:0140999
GeneOntologyMolecularFunctionunmethylated CpG binding

KMT2B KMT2A

4.34e-0410632GO:0045322
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM7A PHF8

5.29e-0411632GO:0051864
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RCC1L SBF1 KALRN RIC8A TIAM2

8.08e-04231635GO:0005085
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

KDM7A PHF8

8.70e-0414632GO:0032454
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RCC1L SGSM1 SBF1 KALRN RIC8A ARHGAP35 TIAM2

1.06e-03507637GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RCC1L SGSM1 SBF1 KALRN RIC8A ARHGAP35 TIAM2

1.06e-03507637GO:0030695
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

FLT1 IGF2R NRG2

1.14e-0365633GO:0004714
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

PTK2B FLT1 IGF2R NRG2

1.14e-03145634GO:0004713
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2B KMT2A

1.79e-0320632GO:0042800
GeneOntologyMolecularFunctionankyrin binding

FLNC PLEC

2.37e-0323632GO:0030506
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

FLT1 IGF2R NRG2

2.46e-0385633GO:0019199
GeneOntologyMolecularFunctionkinase activity

PTK2B FLT1 IGF2R MYLK KALRN TK1 NRG2 PRKD1

2.67e-03764638GO:0016301
GeneOntologyMolecularFunctionprotein kinase activity

PTK2B FLT1 IGF2R MYLK KALRN NRG2 PRKD1

2.75e-03600637GO:0004672
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM7A PHF8

3.51e-0328632GO:0141052
GeneOntologyBiologicalProcessactomyosin structure organization

PTK2B FLNC PDLIM1 OBSL1 PRKD1 PLEC EPB41L1

7.35e-06239627GO:0031032
GeneOntologyBiologicalProcessactin cytoskeleton organization

PTK2B FLNB FLNC PDLIM1 OBSL1 LRP1 PRKN PRKD1 PLEC ARHGAP35 EPB41L1

2.41e-058036211GO:0030036
GeneOntologyBiologicalProcessestablishment or maintenance of actin cytoskeleton polarity

PDLIM1 ARHGAP35

5.31e-054622GO:0030950
GeneOntologyBiologicalProcessactin filament-based process

PTK2B FLNB FLNC PDLIM1 OBSL1 LRP1 PRKN PRKD1 PLEC ARHGAP35 EPB41L1

7.64e-059126211GO:0030029
GeneOntologyBiologicalProcessmyofibril assembly

FLNC OBSL1 PRKD1 PLEC

1.31e-0486624GO:0030239
GeneOntologyBiologicalProcessnegative regulation of heterochromatin formation

KMT2A PHF8

1.32e-046622GO:0031452
GeneOntologyBiologicalProcessregulation of postsynaptic membrane neurotransmitter receptor levels

MYLK KALRN LRP1 PRKN EPB41L1

1.34e-04164625GO:0099072
GeneOntologyBiologicalProcessstriated muscle cell development

FLNC OBSL1 PRKD1 PLEC

1.49e-0489624GO:0055002
GeneOntologyBiologicalProcessnegative regulation of chromatin organization

KMT2A PHF8

1.85e-047622GO:1905268
GeneOntologyBiologicalProcessmuscle structure development

FLNB FLNC MYLK PDLIM1 UNC45B NTF3 OBSL1 PRKD1 PLEC TNNI1

2.22e-048586210GO:0061061
GeneOntologyCellularComponentZ disc

FLNB FLNC PDLIM1 UNC45B OBSL1 PRKD1 PLEC

3.15e-07151627GO:0030018
GeneOntologyCellularComponentI band

FLNB FLNC PDLIM1 UNC45B OBSL1 PRKD1 PLEC

5.98e-07166627GO:0031674
GeneOntologyCellularComponentsarcomere

FLNB FLNC PDLIM1 UNC45B OBSL1 PRKD1 PLEC TNNI1

7.03e-07249628GO:0030017
GeneOntologyCellularComponentmyofibril

FLNB FLNC PDLIM1 UNC45B OBSL1 PRKD1 PLEC TNNI1

1.40e-06273628GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

FLNB FLNC PDLIM1 UNC45B OBSL1 PRKD1 PLEC TNNI1

2.20e-06290628GO:0043292
GeneOntologyCellularComponentanchoring junction

PTK2B FLNB FLNC FLT1 IGF2R MYLK PTPRK PDLIM1 OBSL1 LRP1 MPDZ PRKD1 PLEC

4.57e-069766213GO:0070161
GeneOntologyCellularComponentfocal adhesion

PTK2B FLNB FLNC FLT1 IGF2R PDLIM1 LRP1 PLEC

3.91e-05431628GO:0005925
GeneOntologyCellularComponentcell-substrate junction

PTK2B FLNB FLNC FLT1 IGF2R PDLIM1 LRP1 PLEC

4.74e-05443628GO:0030055
GeneOntologyCellularComponentactin cytoskeleton

FLNB FLNC FLT1 MYLK ACACA PDLIM1 KALRN ARHGAP35 TNNI1

4.75e-05576629GO:0015629
GeneOntologyCellularComponentperinuclear region of cytoplasm

PTK2B IGF2R SBF1 KALRN UNC45B OBSL1 LRP1 PRKN PRKD1 PLEC

3.93e-049346210GO:0048471
GeneOntologyCellularComponentcostamere

FLNC PLEC

1.92e-0322622GO:0043034
GeneOntologyCellularComponentpostsynaptic density

PTK2B KALRN LRP1 MPDZ PRKN EPB41L1

2.16e-03451626GO:0014069
DomainMeTrfase_trithorax

KMT2B KMT2A

1.12e-052632IPR016569
DomainIGc2

FLT1 MYLK KALRN OBSL1 NRG2 IGSF1 IGSF3

1.39e-05235637SM00408
DomainIg_sub2

FLT1 MYLK KALRN OBSL1 NRG2 IGSF1 IGSF3

1.39e-05235637IPR003598
DomainIg_I-set

FLT1 MYLK PTPRK KALRN OBSL1 NRG2

4.30e-05190636IPR013098
DomainI-set

FLT1 MYLK PTPRK KALRN OBSL1 NRG2

4.30e-05190636PF07679
DomainActinin_actin-bd_CS

FLNB FLNC PLEC

6.17e-0523633IPR001589
DomainACTININ_2

FLNB FLNC PLEC

6.17e-0523633PS00020
DomainACTININ_1

FLNB FLNC PLEC

6.17e-0523633PS00019
Domain-

FLNB FLNC FLT1 MYLK PTPRK KALRN OBSL1 NRG2 IGSF1 IGSF3

6.93e-0566363102.60.40.10
DomainIG

FLT1 MYLK PTPRK KALRN OBSL1 NRG2 IGSF1 IGSF3

8.16e-05421638SM00409
DomainIg_sub

FLT1 MYLK PTPRK KALRN OBSL1 NRG2 IGSF1 IGSF3

8.16e-05421638IPR003599
DomainFYrich_C

KMT2B KMT2A

1.11e-045632IPR003889
DomainFYrich_N

KMT2B KMT2A

1.11e-045632IPR003888
DomainFYRC

KMT2B KMT2A

1.11e-045632SM00542
DomainFYRN

KMT2B KMT2A

1.11e-045632SM00541
DomainFYRN

KMT2B KMT2A

1.11e-045632PF05964
DomainFYRC

KMT2B KMT2A

1.11e-045632PF05965
DomainFYRC

KMT2B KMT2A

1.11e-045632PS51543
DomainFYRN

KMT2B KMT2A

1.11e-045632PS51542
DomainIg-like_fold

FLNB FLNC FLT1 MYLK PTPRK KALRN OBSL1 NRG2 IGSF1 IGSF3

1.17e-047066310IPR013783
DomainPHD

KMT2B KMT2A KDM7A PHF8

1.19e-0475634PF00628
DomainZnf_PHD-finger

KMT2B KMT2A KDM7A PHF8

1.46e-0479634IPR019787
DomainPHD

KMT2B KMT2A KDM7A PHF8

2.32e-0489634SM00249
DomainIG_LIKE

FLT1 MYLK PTPRK KALRN OBSL1 NRG2 IGSF1 IGSF3

2.35e-04491638PS50835
DomainZnf_PHD

KMT2B KMT2A KDM7A PHF8

2.52e-0491634IPR001965
DomainIg-like_dom

FLT1 MYLK PTPRK KALRN OBSL1 NRG2 IGSF1 IGSF3

2.76e-04503638IPR007110
DomainZF_PHD_2

KMT2B KMT2A KDM7A PHF8

2.97e-0495634PS50016
DomainZF_PHD_1

KMT2B KMT2A KDM7A PHF8

3.10e-0496634PS01359
DomainFN3

FLNC MYLK PTPRK KALRN OBSL1

3.99e-04185635SM00060
DomainIG_FLMN

FLNB FLNC

4.95e-0410632SM00557
DomainFilamin

FLNB FLNC

6.04e-0411632PF00630
DomainZnf_CXXC

KMT2B KMT2A

6.04e-0411632IPR002857
DomainZF_CXXC

KMT2B KMT2A

6.04e-0411632PS51058
DomainFILAMIN_REPEAT

FLNB FLNC

6.04e-0411632PS50194
Domainzf-CXXC

KMT2B KMT2A

6.04e-0411632PF02008
DomainFilamin/ABP280_rpt

FLNB FLNC

6.04e-0411632IPR001298
DomainFilamin/ABP280_repeat-like

FLNB FLNC

6.04e-0411632IPR017868
DomainFN3_dom

FLNC MYLK PTPRK KALRN OBSL1

6.94e-04209635IPR003961
DomainPost-SET_dom

KMT2B KMT2A

1.30e-0316632IPR003616
DomainPostSET

KMT2B KMT2A

1.30e-0316632SM00508
DomainPOST_SET

KMT2B KMT2A

1.30e-0316632PS50868
DomainCH

FLNB FLNC PLEC

1.38e-0365633SM00033
DomainZnf_FYVE_PHD

KMT2B KMT2A KDM7A PHF8

1.53e-03147634IPR011011
DomainCH

FLNB FLNC PLEC

1.70e-0370633PF00307
Domain-

FLNB FLNC PLEC

1.78e-03716331.10.418.10
DomainCH

FLNB FLNC PLEC

1.92e-0373633PS50021
DomainCH-domain

FLNB FLNC PLEC

2.08e-0375633IPR001715
Domainfn3

MYLK PTPRK KALRN OBSL1

2.18e-03162634PF00041
DomainEPHD

KMT2B KMT2A

2.48e-0322632PS51805
DomainJmjC

KDM7A PHF8

2.95e-0324632PF02373
DomainPH_dom-like

PTK2B SBF1 KALRN PRKD1 EPB41L1 TIAM2

3.08e-03426636IPR011993
DomainAT_hook

KMT2B KMT2A

3.72e-0327632SM00384
DomainAT_hook_DNA-bd_motif

KMT2B KMT2A

3.72e-0327632IPR017956
Domainig

FLT1 PTPRK OBSL1 IGSF1

3.87e-03190634PF00047
DomainImmunoglobulin

FLT1 PTPRK OBSL1 IGSF1

3.87e-03190634IPR013151
DomainSpectrin_repeat

KALRN PLEC

4.29e-0329632IPR002017
DomainFN3

MYLK PTPRK KALRN OBSL1

4.56e-03199634PS50853
DomainJMJC

KDM7A PHF8

5.20e-0332632PS51184
DomainSpectrin/alpha-actinin

KALRN PLEC

5.20e-0332632IPR018159
DomainJmjC_dom

KDM7A PHF8

5.20e-0332632IPR003347
DomainSPEC

KALRN PLEC

5.20e-0332632SM00150
DomainJmjC

KDM7A PHF8

5.53e-0333632SM00558
Domain-

UNC45B TERB1 PSMD5 RIC8A

6.69e-032226341.25.10.10
PathwayWP_NPHP1_DELETION_SYNDROME

PTK2B FLNB FLNC

5.63e-0611473M48099
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

FLT1 PTPRK KALRN OBSL1 IGSF1 IGSF3

5.08e-0716263625826454
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNC IGF2R KMT2B ACACA SBF1 SUGP2 KALRN RIC8A PLEC ARHGAP35 TIAM2 IGSF3

5.97e-071105631235748872
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2B ACACA SUGP2 PDLIM1 CCT8 KMT2A MPDZ ARHGAP35 PHF8

6.33e-0754963938280479
Pubmed

Proteome analysis of the circadian clock protein PERIOD2.

FLNC ACACA CCT8 PRKD1 PLEC

8.04e-079463535122331
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

FLNB FLNC FLT1 IGF2R PDLIM1 LRP1 PLEC

8.62e-0728563721423176
Pubmed

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.

FLNB UNC45B CCT8 PLEC

9.41e-074163424614889
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

IGF2R SBF1 SUGP2 USP11 ACTR6 OBSL1 CCT8

1.21e-0630063728561026
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRANK1 KMT2B SUGP2 IGSF1 EPB41L1

1.33e-061046359205841
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KMT2B KMT2A KDM7A PHF8

1.95e-064963434368113
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNB FLNC IGF2R ACACA SBF1 SUGP2 USP11 KMT2A PLEC

2.63e-0665363922586326
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

FLNB FLNC IGF2R SUGP2 PDLIM1 CCT8

2.64e-0621563635973513
Pubmed

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.

KMT2B KMT2A

3.23e-06263228723559
Pubmed

The limits of promiscuity: isoform-specific dimerization of filamins.

FLNB FLNC

3.23e-06263212525170
Pubmed

A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.

FLNB FLNC

3.23e-0626329694715
Pubmed

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.

KDM7A PHF8

3.23e-06263220023638
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNB FLNC ACACA SBF1 SUGP2 TK1 USP11 CCT8 PSMD5 RIC8A PLEC PHF8

4.86e-061353631229467282
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

FLNB ACACA SUGP2 KALRN CCT8 PLEC ARHGAP35 NFS1 SLC4A4 EPB41L1 IGSF3

5.73e-061139631136417873
Pubmed

Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA.

FLNB FLNC CCT8 PLEC

6.09e-066563434645483
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KMT2B KMT2A KDM7A

7.36e-062163327626377
Pubmed

Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.

FLNB FLNC ACACA

8.51e-062263318487259
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CNTNAP5 IGF2R SBF1 KALRN LRP1 CCT8 MPDZ PRKD1 SLC4A4 EPB41L1

8.55e-06963631028671696
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PTK2B FLNB FLNC SBF1 SUGP2 KALRN CCT8 KMT2A PLEC ARHGAP35 SLC4A4 EPB41L1

8.57e-061431631237142655
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNB FLNC SBF1 PTPRK TK1 USP11 OBSL1 LRP1 CCT8 MPDZ

9.44e-06974631028675297
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNB FLNC

9.68e-06363211252955
Pubmed

Association of SET domain and myotubularin-related proteins modulates growth control.

SBF1 KMT2A

9.68e-0636329537414
Pubmed

Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs.

KDM7A PHF8

9.68e-06363239273051
Pubmed

Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.

FLNC PLEC

9.68e-06363221223964
Pubmed

[Time dependent expression profiling of PTK2B and its relationship with Aβ, Tau and LRP-1 in hippocampus and blood of APPswe/PS1dE9 double-transgenic mouse].

PTK2B LRP1

9.68e-06363235634664
Pubmed

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

PTK2B FLT1

9.68e-06363219718025
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNB FLNC

9.68e-06363212393796
Pubmed

Hypoxia induces metalloproteinase-9 activation and human vascular smooth muscle cell migration through low-density lipoprotein receptor-related protein 1-mediated Pyk2 phosphorylation.

PTK2B LRP1

9.68e-06363224072693
Pubmed

Relationship among LRP1 expression, Pyk2 phosphorylation and MMP-9 activation in left ventricular remodelling after myocardial infarction.

PTK2B LRP1

9.68e-06363228378397
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNB FLNC

9.68e-06363211153914
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 FLNB ODF2L SGSM1 ACACA SUGP2 NTF3 LRP1 PRKN PRKD1 ARHGAP35 EPB41L1

1.28e-051489631228611215
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

PTK2B KMT2B SBF1 USP11 LRP1 ARHGAP35 ZNF169

1.72e-0545063716751776
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FLNB ODF2L SUPT20H PTPRK KALRN USP11 OBSL1 LRP1 PSMD5 PCMTD2 PLEC

1.77e-051285631135914814
Pubmed

A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.

PTK2B ARHGAP35

1.93e-05463219435801
Pubmed

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.

FLNB FLNC

1.93e-05463211739414
Pubmed

Structural interaction and functional regulation of polycystin-2 by filamin.

FLNB FLNC

1.93e-05463222802962
Pubmed

A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.

KMT2B KMT2A

1.93e-05463223129768
Pubmed

Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation.

KMT2B KMT2A

1.93e-05463217166833
Pubmed

Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA.

KMT2B KMT2A

1.93e-05463234156981
Pubmed

WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket.

KMT2B KMT2A

1.93e-05463218840606
Pubmed

Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking.

MYLK KALRN

1.93e-05463219706030
Pubmed

Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.

KMT2B KMT2A

1.93e-05463226267306
Pubmed

MLL1 is required for PAX7 expression and satellite cell self-renewal in mice.

KMT2B KMT2A

1.93e-05463231534153
Pubmed

Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.

PTK2B FLT1

1.93e-05463211751905
Pubmed

Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.

KMT2B KMT2A

1.93e-05463225834037
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

FLNB FLNC ACACA SUGP2 TERB1 CCT8 PLEC

2.49e-0547763731300519
Pubmed

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development.

KDM7A PHF8

3.22e-05563220622853
Pubmed

Evolving Catalytic Properties of the MLL Family SET Domain.

KMT2B KMT2A

3.22e-05563226320581
Pubmed

Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

KMT2B KMT2A

3.22e-05563225561738
Pubmed

MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.

KMT2B KMT2A

3.22e-05563228609655
Pubmed

HIV infection of T cells: actin-in and actin-out.

FLNB FLNC

3.22e-05563219366992
Pubmed

Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions.

NTF3 LRP1

3.22e-0556327537086
Pubmed

Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.

FLNB FLNC

3.22e-05563212006559
Pubmed

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

FLNB FLNC

3.22e-05563217360453
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

FLT1 RCC1L SUPT20H SBF1 PSMD5 RIC8A PCMTD2 ARHGAP35

3.38e-0568963836543142
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

SUPT20H KMT2B SUGP2 USP11 PPIL3 KMT2A

3.49e-0533963630415952
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

PTK2B MYLK OBSL1 KMT2A PSMD5 PRKD1 PLEC NFS1 SLC4A4

3.69e-0591063936736316
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

FLNB FLNC IGF2R ACACA TK1 CCT8 PSMD5 PLEC

4.05e-0570763819738201
Pubmed

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

IGF2R ACACA PDLIM1 USP11 PLEC

4.23e-0521263533462405
Pubmed

Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.

KMT2B KMT2A

4.82e-05663224176642
Pubmed

MLL associates specifically with a subset of transcriptionally active target genes.

KMT2B KMT2A

4.82e-05663216199523
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

FLNB FLNC IGF2R ACACA SBF1 PTPRK LRP1 PLEC NFS1 TAP2 EPB41L1

5.37e-051451631130550785
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

SBF1 USP11 OBSL1 DBR1 PHF8

5.38e-0522363533187986
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

FLNB MYLK SBF1 OBSL1 EPB41L1

5.61e-0522563525277244
Pubmed

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.

FLNB ACACA PDLIM1 CCT8 ARHGAP35

5.73e-0522663531452512
Pubmed

Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.

FLNB FLNC TNNI1

5.75e-054163318157088
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

FLT1 TRANK1 ACACA SUGP2 KALRN DBR1 SVEP1

6.27e-0555263710737800
Pubmed

Impact of WIN site inhibitor on the WDR5 interactome.

KMT2B SBF1 KMT2A

6.64e-054363333472061
Pubmed

The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

FLNB FLNC

6.74e-05763216076904
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

FLNB FLNC IGF2R CCT8 RIC8A PCMTD2 PLEC

7.17e-0556463721565611
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

SUGP2 TK1 USP11 CCT8

8.04e-0512563421654808
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

IGF2R SBF1 PSMD5 EPB41L1

8.55e-0512763430442766
Pubmed

MEKK4 signaling regulates filamin expression and neuronal migration.

FLNB FLNC

8.98e-05863217145501
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

KMT2B KMT2A

8.98e-05863223130995
Pubmed

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

KMT2B KMT2A

8.98e-05863222266653
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNB FLNC ACACA CCT8 KMT2A PSMD5 PLEC ZNF169

1.02e-0480763830575818
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNB KMT2B ACACA LRP1 CCT8 PLEC

1.11e-0441863634709266
Pubmed

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

KMT2B KMT2A

1.15e-04963222665483
Pubmed

Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.

KMT2B KMT2A

1.15e-04963216951254
Pubmed

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

FLNB FLNC

1.15e-04963211807098
Pubmed

Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity.

FLNB PLEC TAP2

1.17e-045263323182705
Pubmed

Filament-associated TSGA10 protein is expressed in professional antigen presenting cells and interacts with vimentin.

OBSL1 PLEC

1.44e-041063220797700
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

KMT2B KMT2A

1.44e-041063229276034
Pubmed

The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma.

FLNB FLNC

1.44e-041063236357400
Pubmed

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions.

IGF2R CCT8 PLEC

1.47e-045663337059927
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

FLNB CCT8 PSMD5 PLEC IGSF3

1.49e-0427763530745168
Pubmed

Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.

FLNB FLNC

1.76e-041163236579465
Pubmed

USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.

FLNB FLNC

1.76e-041163219015242
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

KMT2B CCT8 KMT2A

1.89e-046163320305087
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

KMT2B KMT2A

2.11e-041263227563068
Pubmed

Selective impairment of P2Y signaling by prostaglandin E2 in macrophages: implications for Ca2+-dependent responses.

ACACA PRKD1

2.49e-041363223479225
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KMT2B KMT2A

2.49e-041363224619213
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

FLNB FLNC ACACA PDLIM1 USP11 CCT8 PSMD5 RIC8A PLEC EPB41L1

2.69e-041455631022863883
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

ACACA SUGP2 TK1 CCT8 PSMD5 RIC8A DPH6

2.80e-0470463729955894
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

BDP1 FLT1 TRANK1 SUPT20H ACACA KMT2A

2.82e-0449763636774506
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

FLNB SUGP2 PSMD5 RIC8A ARHGAP35 EPB41L1

2.85e-0449863636634849
Pubmed

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

FLNB PDLIM1 CCT8 PLEC ARHGAP35

3.21e-0432763515592455
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FLT1 MYLK KALRN OBSL1 NRG2

5.97e-05161475593
GeneFamilyPHD finger proteins

KMT2B KMT2A KDM7A PHF8

8.69e-059047488
GeneFamilyImmunoglobulin like domain containing

FLT1 PTPRK OBSL1 IGSF1 IGSF3

1.40e-04193475594
GeneFamilyZinc fingers CXXC-type

KMT2B KMT2A

4.29e-0412472136
GeneFamilyPHD finger proteins|Lysine demethylases

KDM7A PHF8

1.76e-0324472485
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2B KMT2A

3.52e-0334472487
GeneFamilyPDZ domain containing

PDLIM1 MPDZ TIAM2

7.21e-031524731220
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTK2B EPB41L1

7.48e-03504721293
GeneFamilyFibronectin type III domain containing

MYLK PTPRK KALRN

8.29e-03160473555
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

BDP1 TERB1

8.38e-0353472532
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KALRN TIAM2

1.28e-0266472722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SBF1 PRKD1 TIAM2

1.64e-02206473682
CoexpressionDEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN

FLNC IGF2R SBF1 OBSL1 PLEC ARHGAP35 IGSF3

3.99e-06276627M3063
CoexpressionGSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_DN

FLT1 MYLK PDLIM1 NTF3 PRKN LCT

7.45e-06198626M8400
CoexpressionSCHLOSSER_SERUM_RESPONSE_UP

PTK2B TRANK1 KMT2B ARHGAP35 TNNI1

1.23e-05126625M16381
CoexpressionPILON_KLF1_TARGETS_UP

FLT1 MYLK SUGP2 LIPG OBSL1 KMT2A IGSF1 IGSF3

2.37e-05503628M2226
CoexpressionATM_DN.V1_UP

PTK2B FLT1 ACACA LCT TIAM2

2.51e-05146625M2692
CoexpressionPILON_KLF1_TARGETS_UP

FLT1 MYLK SUGP2 LIPG OBSL1 KMT2A IGSF1 IGSF3

3.97e-05541628MM1061
CoexpressionSASSON_RESPONSE_TO_FORSKOLIN_DN

FLNC TK1 PRKD1 ARHGAP35

4.98e-0585624M12924
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ACTC_POS_SMC_CELL

RNF150 FLNB FLNC TK1 NTF3 TNNI1 EPB41L1 IGSF3

7.21e-05589628M45662
CoexpressionGSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP

FLNC ARFRP1 MYLK TIAM2 IGSF3

1.09e-04199625M7325
CoexpressionGSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN

ARFRP1 TERB1 KMT2A PLEC ARHGAP35

1.09e-04199625M6030
CoexpressionGSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_DN

USP11 KDM7A PHF8 LCT EPB41L1

1.12e-04200625M7066
CoexpressionGSE27786_CD4_TCELL_VS_NKCELL_UP

FLNB SUPT20H KMT2A DBR1 TAP2

1.12e-04200625M4822
CoexpressionGSE7852_THYMUS_VS_FAT_TREG_UP

ACTR6 PPIL3 RFESD IGSF3 DPH6

1.12e-04200625M5743
CoexpressionCAIRO_HEPATOBLASTOMA_CLASSES_DN

TRANK1 MYLK NTF3 SLC4A4 SVEP1

1.50e-04213625M12176
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

PTK2B FLNC CNTNAP5 TRANK1 IGF2R ACACA KALRN LIPG USP11 ACTR6 OBSL1 LRP1 MPDZ PRKD1 PHF8 SVEP1

1.24e-098276216gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000

PTK2B RNF150 FLNC CNTNAP5 TRANK1 PDLIM1 KALRN LIPG ACTR6 OBSL1 LRP1 PRKD1 TNNI1 SVEP1 TIAM2

1.52e-088496215gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

PTK2B FLNC TRANK1 PDLIM1 TK1 NTF3 USP11 OBSL1 LRP1 PRKD1 PHF8 TNNI1 SLC4A4 SVEP1

5.04e-087936214gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

PTK2B FLNC TRANK1 LIPG NTF3 USP11 OBSL1 LRP1 PCMTD2 KDM7A PHF8 TNNI1 SVEP1

2.65e-077686213gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500

PTK2B CNTNAP5 TRANK1 ACACA LIPG ACTR6 OBSL1 PRKD1 KDM7A PHF8

4.58e-074326210gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

FLNC CNTNAP5 IGF2R PTPRK KALRN LIPG USP11 ACTR6 OBSL1 LRP1 MPDZ PRKD1 SVEP1

6.47e-078316213gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000

FLNC CNTNAP5 PDLIM1 KALRN LIPG ACTR6 OBSL1 LRP1 PRKD1 TNNI1 SVEP1 EPB41L1 TIAM2

9.27e-078586213gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

PTK2B FLNC TRANK1 IGF2R MYLK ACACA LIPG USP11 OBSL1 LRP1 PHF8 SVEP1

2.02e-067736212gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000

PTK2B CNTNAP5 TRANK1 ACACA LIPG ACTR6 OBSL1 PRKD1 KDM7A PHF8 SLC4A4 EPB41L1

4.57e-068376212gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

FLNC IGF2R KALRN LIPG USP11 LRP1 MPDZ SVEP1

5.94e-06337628gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000

PTK2B TRANK1 ACACA PDLIM1 LIPG OBSL1 PRKD1 PCMTD2 KDM7A PHF8 TNNI1 IGSF3

7.96e-068846212gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

PTK2B FLNC TRANK1 LIPG USP11 OBSL1 LRP1 PHF8

1.04e-05364628gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

FLNC CNTNAP5 TRANK1 ACACA ACTR6 OBSL1 LRP1 MPDZ PRKD1 PHF8 SLC4A4

1.46e-057836211gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

FLNC CNTNAP5 KALRN LIPG ACTR6 OBSL1 LRP1 PRKD1 TNNI1 SLC4A4 EPB41L1

1.72e-057976211gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000

PTK2B TRANK1 PCMTD2 KDM7A PHF8 TNNI1

1.98e-05191626gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

FLNC CNTNAP5 KALRN LIPG ACTR6 LRP1 PRKD1 SVEP1

2.81e-05418628gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

RNF150 FLNC KALRN LIPG LRP1 SVEP1 TIAM2

3.33e-05311627gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

FLNC IGF2R MYLK LIPG USP11 LRP1 SVEP1

5.44e-05336627gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500

CNTNAP5 ACTR6 OBSL1 PRKD1 EPB41L1

6.56e-05145625gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

FLNC IGF2R KALRN USP11 LRP1 MPDZ SVEP1

7.55e-05354627gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

FLNC TRANK1 KALRN ACTR6 OBSL1 LRP1 PRKD1 TNNI1 SLC4A4 EPB41L1

9.62e-057976210gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_100

PTK2B CNTNAP5 TRANK1 ACTR6

1.02e-0483624gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_100
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_200

PTK2B CNTNAP5 TRANK1 ACTR6 PHF8

1.17e-04164625gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

FLNC CNTNAP5 TRANK1 ACTR6 LRP1 PRKD1 SLC4A4

1.33e-04388627gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#2

IGF2R SUGP2 PDLIM1 NTF3 PPIL3 LRP1 RIC8A SVEP1

1.39e-04525628Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K2
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_200

PTK2B TRANK1 PHF8

1.58e-0436623gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_200
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500

PTK2B TRANK1 KDM7A PHF8

1.86e-0497624gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k1_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

FLNC LIPG USP11 LRP1 SVEP1

1.91e-04182625gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

FLNC CNTNAP5 USP11 ACTR6 LRP1 PRKD1 SVEP1

2.27e-04423627gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

TRANK1 ACACA PHF8

2.33e-0441623gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_1000
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500

PTK2B FLNC CNTNAP5 TRANK1 PDLIM1 ACTR6 PRKD1

2.58e-04432627gudmap_dev gonad_e11.5_M_GonMes_Sma_500
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500

PTK2B TRANK1 OBSL1 PRKD1 KDM7A PHF8 TNNI1

2.61e-04433627gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

FLNC TRANK1 LIPG ACTR6 OBSL1 LRP1 PRKD1 SLC4A4 SVEP1

2.80e-04740629gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

FLNC LIPG NTF3 USP11 LRP1 SVEP1

2.85e-04310626gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

FLNC KALRN LIPG LRP1 SVEP1

3.46e-04207625gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_200

PTK2B TRANK1 PHF8

3.97e-0449623gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

FLNC IGF2R MYLK PDLIM1 TK1 LIPG NTF3 LRP1 SVEP1

4.01e-04777629gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_200

CNTNAP5 ACTR6 PRKD1

4.73e-0452623gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_200
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000

CNTNAP5 ACTR6 OBSL1 PRKD1 EPB41L1

4.86e-04223625gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k2_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_500

TRANK1 PHF8

5.43e-0412622gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k1_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

FLNC TRANK1 LIPG USP11 LRP1 SVEP1

5.94e-04356626gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

PTK2B FLNC TRANK1 NTF3 OBSL1 LRP1

7.57e-04373626gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000

PTK2B TRANK1 ACACA KDM7A PHF8

8.29e-04251625gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500

FLNC ACTR6 OBSL1 LRP1 PRKD1 SLC4A4

8.93e-04385626gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000

CNTNAP5 ACTR6 OBSL1 PRKD1 EPB41L1

9.54e-04259625gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_1000
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000

PTK2B TRANK1 OBSL1 PRKD1 PCMTD2 KDM7A PLEC PHF8 TNNI1

9.77e-04880629gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_200

FLNC CNTNAP5 ACTR6 PRKD1

1.02e-03152624gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_200
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

FLNC LIPG LRP1 SLC4A4 SVEP1

1.06e-03265625gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

PTK2B TRANK1 PHF8 TNNI1

1.10e-03155624gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k1_1000
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500

CNTNAP5 TRANK1 ACTR6 OBSL1 PRKD1 EPB41L1

1.30e-03414626gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200

CNTNAP5 TRANK1 ACTR6 PRKD1

1.38e-03165624gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

FLNC LIPG USP11 LRP1

1.38e-03165624gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_100

PTK2B TRANK1

1.39e-0319622gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_100
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_500

OBSL1 PRKD1 TNNI1

1.43e-0376623gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_500
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_1000_k-means-cluster#5

FLNC UNC45B NRG2 PRKN TNNI1 SVEP1

1.46e-03424626geo_heart_1000_K5
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGSM1 LIPG OBSL1 NRG2 TNNI1 IGSF3

3.01e-0719163654f07e4de61735051498846afb44b1798bed8144
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FLNB MYLK KALRN NTF3 PRKD1

6.12e-06183635cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGSM1 LIPG OBSL1 NRG2 TNNI1

6.45e-06185635686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

FLNB MYLK KALRN NTF3 PRKD1

6.97e-0618863534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FLNB MYLK KALRN NTF3 PRKD1

7.16e-061896356b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R MYLK SUGP2 LRP1 SVEP1

7.16e-061896350c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R MYLK USP11 LRP1 SVEP1

7.53e-061916353379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell(2)_Fibroblasts-(21)_Fibro-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PDLIM1 LRP1 PLEC EPB41L1 PADI3

7.53e-061916355ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK KALRN NTF3 LRP1 SVEP1

8.33e-0619563549c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK KALRN NTF3 LRP1 SVEP1

8.33e-06195635dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|(2)_5-FU / Stress and Cell class

MYLK PDLIM1 LRP1 MPDZ IGSF3

8.54e-06196635cc0a172de71d9a1a882c9e78652dae70e007d012
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK KALRN NTF3 LRP1 SVEP1

8.54e-06196635fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK KALRN NTF3 LRP1 SVEP1

8.54e-06196635802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

MYLK PDLIM1 LRP1 MPDZ IGSF3

8.75e-06197635434ae0231972acba12d06279908cf407e70511ac
ToppCellILEUM-non-inflamed-(8)_Fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLNB MYLK PDLIM1 LRP1 SVEP1

9.19e-06199635d9d7f36b4b5592b7855448730044c90997b55499
ToppCellILEUM-non-inflamed-(8)_Fibroblast|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLNB MYLK PDLIM1 NTF3 LRP1

9.19e-061996356a0df9a2f30480043f9c1d7fbdede17eb0910cac
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RNF150 FLNC MYLK KALRN NTF3

9.41e-06200635a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

MYLK LIPG NTF3 LRP1 SLC4A4

9.41e-062006355ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

MYLK LIPG NTF3 LRP1 SLC4A4

9.41e-06200635cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP5 PDLIM1 GCNT4 TIAM2

4.77e-0514163440ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col18a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRK PDLIM1 GCNT4 TIAM2

5.76e-05148634fc80c02b51cf55a04ce550838ee2f41d8f656f41
ToppCellPBMC-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

ODF2L MYLK PTPRK OBSL1

6.39e-051526341a3f8ed476aa9a39742b4684be2c704669e4a3d0
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

NRG2 RFESD PP2D1 ZNF169

6.89e-0515563415bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

MYLK LIPG NTF3 SVEP1

7.61e-051596343f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RNF150 FLNC MYLK NTF3

7.61e-051596347cda111bb98f1241989e49d490bdf51a712ea589
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FLNB NRG2 PP2D1 ZNF169

7.79e-051606348aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NRG2 RFESD PP2D1 ZNF169

7.98e-051616342fe77af3b41e6eacb707a64feea18f9991618173
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RNF150 SBF1 IGSF1 SLC4A4

8.57e-05164634583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B CNTNAP5 TRANK1 PRKD1

8.78e-051656341b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B CNTNAP5 TRANK1 PRKD1

8.78e-05165634b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B NRG2 LCT IGSF3

9.20e-051676343dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B NRG2 LCT IGSF3

9.20e-0516763495b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B NRG2 LCT IGSF3

9.20e-051676349480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CNTNAP5 MYLK KALRN NTF3

9.20e-05167634c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

FLT1 PDLIM1 KALRN LIPG

9.63e-05169634e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIPG OBSL1 NRG2 TNNI1

9.63e-0516963405e12524d68d409fed386ffad233305683b4575b
ToppCellCOVID-19_Moderate-Treg|World / disease group, cell group and cell class

ODF2L TNNI1 GCNT4 SVEP1

9.63e-0516963427ad11239559b025bef582f89b2a83501d9d3993
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC MYLK NTF3 TNNI1

9.85e-05170634cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC MYLK NTF3 TNNI1

9.85e-05170634da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF150 PRKD1 TNNI1 IGSF3

1.05e-0417363409a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF150 PRKD1 TNNI1 IGSF3

1.05e-04173634bfec038a6783f166240da4861e100643c6ea80a5
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PTPRK OBSL1 NRG2 IGSF3

1.05e-04173634ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLNB ODF2L NTF3 SLC4A4

1.05e-04173634464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP5 MYLK PTPRK KDM7A

1.05e-041736348ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PTPRK OBSL1 NRG2 IGSF3

1.08e-04174634110369f6b78de34a6d934b5b47cecd023347bc80
ToppCellTCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue|TCGA-Prostate / Sample_Type by Project: Shred V9

NRG2 IGSF1 GCNT4 PADI3

1.08e-04174634de6c1ebca36ec8060ddcafc270c45d6ab1caec2c
ToppCellTCGA-Prostate-Solid_Tissue_Normal|TCGA-Prostate / Sample_Type by Project: Shred V9

NRG2 IGSF1 GCNT4 PADI3

1.08e-04174634abdb5a89118b82bb64469fc41c163bd2b282b0c0
ToppCellTCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue|TCGA-Prostate / Sample_Type by Project: Shred V9

NRG2 IGSF1 GCNT4 PADI3

1.08e-041746340dde0e9ef987c52cb29a238f15568a83424d02f6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTK2B PTPRK PDLIM1 LIPG

1.10e-04175634c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRK PDLIM1 LIPG GCNT4

1.13e-04176634a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB FLT1 PLEC TNNI1

1.13e-0417663477516048aefbe1f48e825052756df0c310c1c486
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

RNF150 SLC4A4 EPB41L1 IGSF3

1.13e-0417663436f77d878a53b30465b0dea8333a3865dba75613
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB FLT1 PLEC TNNI1

1.13e-0417663496779273b94345250cf53ba671203345b43d9e00
ToppCellPBMC-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

FLNB MYLK KALRN OBSL1

1.18e-041786340667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R MYLK LIPG GCNT4

1.20e-0417963456db12467b445f2b8ef92af50779eeab10413eb2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF735 LRP1 LCT SVEP1

1.23e-04180634ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ACACA PTPRK PRKD1 SLC4A4

1.23e-04180634198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF150 SBF1 KALRN ACTR6

1.23e-041806347368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF150 FLNC MYLK PRKD1

1.25e-04181634ab0f300d14b62cef57f1b0bdae143b8dfe8e6975
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R MYLK LRP1 SVEP1

1.28e-04182634ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B RNF150 TRANK1 TIAM2

1.28e-04182634d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B RNF150 TRANK1 TIAM2

1.28e-041826346cde859edfe7607bd7ada89d20258413d06f4207
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB FLT1 UNC45B SLC4A4

1.28e-04182634c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB FLT1 UNC45B SLC4A4

1.28e-04182634d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLNB ODF2L NTF3 SLC4A4

1.28e-041826343f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

FLNB MYLK KALRN NTF3

1.31e-04183634818fd886e0188091310825f9145fa53328f2c979
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACACA PTPRK PRKD1 SLC4A4

1.31e-041836346847c1252d6bb105524f812658112517fd351eab
ToppCellPericytes-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

FLNC MYLK UNC45B NTF3

1.34e-04184634cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYLK PDLIM1 KALRN GCNT4

1.34e-04184634ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RNF150 FLNC UNC45B PRKN

1.36e-04185634549eeb521c3985bff396ea0f202db21822efa51f
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

FLNB FLT1 PDLIM1 KALRN

1.36e-04185634f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellPBMC-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

RNF150 PRKD1 TNNI1 IGSF3

1.36e-041856344b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MYLK MPDZ SVEP1 IGSF3

1.39e-04186634a832c1e0035bcd559722eccf262c145deb3494c7
ToppCellmegakaryocytic-Megakaryocyte|World / Lineage and Cell class

MYLK PDLIM1 KALRN TK1

1.39e-04186634acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MYLK MPDZ SVEP1 IGSF3

1.39e-04186634f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

MYLK MPDZ SVEP1 IGSF3

1.39e-041866346ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 PDLIM1 UNC45B TAP2

1.42e-041876347abc174a06bf07b5f6efe0a370fbb1c23e0079b3
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 PDLIM1 UNC45B TAP2

1.42e-04187634f9863428943b695f26bd680e6fc5aeb38ec3422f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYLK KALRN SLC4A4 SVEP1

1.42e-04187634a9316e2818217ec5feae9cf8816f7249803caee6
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 PDLIM1 UNC45B TAP2

1.42e-04187634b0a2e417b4eb9a185033e89c5df3431c11488688
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PDLIM1 UNC45B NTF3 TNNI1

1.42e-04187634406ff9327d3109fe1e251629c4c617b00a573dc2
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R MYLK LRP1 SVEP1

1.45e-041886343f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

FLNB FLT1 PDLIM1 KALRN

1.45e-04188634d582b76fc2faac526c9bf97503041129e1a6a211
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FLT1 PDLIM1 UNC45B

1.48e-04189634d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB FLT1 PLEC TNNI1

1.48e-04189634feedac2751ed770f80bc56fec31662b5b3826f58
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FLT1 PDLIM1 UNC45B

1.48e-04189634476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RNF150 MYLK IGSF1 SLC4A4

1.48e-04189634f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FLT1 PDLIM1 UNC45B

1.48e-041896343fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R MYLK LIPG GCNT4

1.48e-04189634ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellfacs-Heart-LA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FLT1 PDLIM1 UNC45B

1.51e-04190634911b93c4c828ef2d867b91a5eced2dc12a1baf27
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FLT1 PDLIM1 UNC45B

1.51e-0419063438a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

MYLK LRP1 MPDZ IGSF3

1.51e-04190634ec0ab31266583a0966ac7615d5c0fabb7b7e66e8
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FLT1 PDLIM1 UNC45B

1.51e-04190634bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FLT1 PDLIM1 UNC45B

1.51e-04190634d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN NTF3 LRP1 SVEP1

1.54e-04191634a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK LRP1 PRKD1 SVEP1

1.54e-04191634b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACACA PTPRK PRKD1 SLC4A4

1.54e-04191634a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

IGF2R MYLK LRP1 SVEP1

1.54e-04191634e7c605b56934d1383237c1f946dbccef25d91368
ToppCellfacs-Aorta-Heart-18m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTF3 LRP1 SVEP1 IGSF3

1.54e-041916346242f83acaf1714e9c1771a832cb67674b19e96d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN NTF3 LRP1 SVEP1

1.54e-041916348f6d592edc32fdb901af30501d4360512334e8c2
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNB FLNC

1.30e-053622DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNB FLNC

1.30e-053622DOID:0111190 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability (implicated_via_orthology)

KDM7A PHF8

1.21e-048622DOID:0060309 (implicated_via_orthology)
DiseaseGlaucoma

MYLK SLC4A4

1.55e-049622C0017601
Diseaseprostate cancer (is_marker_for)

PTK2B KMT2B KMT2A PHF8

3.30e-04156624DOID:10283 (is_marker_for)
Diseasecardiomyopathy (implicated_via_orthology)

LRP1 PRKN TNNI1

4.56e-0471623DOID:0050700 (implicated_via_orthology)
Diseasecopine-1 measurement

NFS1 EPB41L1

5.79e-0417622EFO_0008102
Diseasechildhood onset asthma

ARFRP1 PTPRK LRP1 TAP2 IGSF3

6.88e-04334625MONDO_0005405
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

LIPG OBSL1

7.26e-0419622EFO_0004612, EFO_0008589
DiseaseAdenocarcinoma of lung (disorder)

FLT1 TK1 ARHGAP35 SLC4A4

9.38e-04206624C0152013
Diseasecoronary artery disease (is_implicated_in)

MYLK KALRN LIPG

1.24e-03100623DOID:3393 (is_implicated_in)
Diseasehearing threshold measurement

SGSM1 SUGP2

1.59e-0328622EFO_0007618
Diseasecerebral infarction (is_implicated_in)

KALRN LIPG

1.70e-0329622DOID:3526 (is_implicated_in)
Diseasefactor VIII measurement, coronary artery disease

FLT1 IGF2R TAP2

1.75e-03113623EFO_0001645, EFO_0004630
Diseaseimmature platelet fraction

PDLIM1 KALRN PLEC

1.80e-03114623EFO_0009187
Diseasecervical cancer (is_implicated_in)

KMT2A TAP2

1.82e-0330622DOID:4362 (is_implicated_in)
Diseasefactor XI measurement, coronary artery disease

FLT1 IGF2R TAP2

1.84e-03115623EFO_0001645, EFO_0004694
Diseasewaist circumference

RNF150 ARFRP1 PTPRK PRKD1 PADI3

2.08e-03429625EFO_0004342

Protein segments in the cluster

PeptideGeneStartEntry
VVTREDYEENGHSVC

ACTR6

376

Q9GZN1
RDDCQEYTTEVHSKE

BDP1

2391

A6H8Y1
TRQVYTKCEGDEVED

DPH6

81

Q7L8W6
SVHCEHVEDEGESRY

ACACA

1766

Q13085
HVEDEGESRYKITDI

ACACA

1771

Q13085
CGRKVVENEIYSESH

RCC1L

206

Q96I51
SCEEILRKVHSIEYE

ODF2L

326

Q9ULJ1
EDAGEYVCETRHEAI

OBSL1

1146

O75147
ASEYECEVEKHGRGQ

EPB41L1

106

Q9H4G0
CVGVEEHHAVDIDLY

KDM7A

66

Q6ZMT4
LECKIGERYITHESD

PRKD1

851

Q15139
VHEEDRGKYTCEATN

MYLK

96

Q15746
EEEVDYTVEKCIQHV

NFS1

416

Q9Y697
ATLDKIERCEYDGSH

LRP1

2396

Q07954
EECHVSELEPDKYAV

FLNB

2331

O75369
DRVYCGAGVQKEHEE

PCMTD2

161

Q9NV79
VKVEDAGEYVCEAEN

NRG2

301

O14511
GEYAVHVICDDEDIR

FLNC

636

Q14315
HYDADAIRECAEKVA

KALRN

971

O60229
IAYGTITEVVKCEHE

LIPG

261

Q9Y5X9
IGDVACDSYHKIAED

LCT

1421

P09848
DGVHRVRVDFKEDCD

KMT2B

1166

Q9UMN6
DVCEAYRHVLGQDKV

PADI3

221

Q9ULW8
EHKSHRGEYSVCDSE

NTF3

141

P20783
EKREYSSVCVGREDD

RFESD

11

Q8TAC1
EVEVIGGADKYHSVC

TK1

171

P04183
YDHRVDTECKGVIDL

SBF1

1796

O95248
AECHGVIYVIDSTDE

ARFRP1

91

Q13795
EDKDEGNYSCRTHTE

IGSF1

741

Q8N6C5
SRKEDEGQYECHVTE

IGSF3

501

O75054
THVKDEVRYEVNCSG

GCNT4

61

Q9P109
DGVHRIRVDFKEDCE

KMT2A

1396

Q03164
SKEEHHVCGEYEEQD

DBR1

386

Q9UK59
VGEVQDKYECLHVEA

PTK2B

111

Q14289
AVIDGSEHCEQEVAY

CNTNAP5

666

Q8WYK1
DDTEVYGDFKVTCVE

PTPRK

1001

Q15262
VEDQIYCEKHARERV

PDLIM1

301

O00151
ELHTEKTECGRYGEH

RNF150

66

Q9ULK6
EVPCYVFDEELRKHD

IGF2R

171

P11717
RECKEAYHEGECSAV

PRKN

366

O60260
GAEEHEVCRYKEALE

TAP2

346

Q03519
EAHTYESEVKLRCLE

SVEP1

3136

Q4LDE5
KCDEGVERYIRDAHT

ARHGAP35

201

Q9NRY4
IKGEVDEEDAALYRH

RIC8A

236

Q9NPQ8
ERDHFRKICEEYITG

UNC45B

371

Q8IWX7
RVDECEVHKGGYNDL

ZNF735

131

P0CB33
VVSEECFYETESHGK

TIAM2

1686

Q8IVF5
IHEVYEEGAACKDGR

MPDZ

1656

O75970
HTDVGDIKIEVFCER

PPIL3

6

Q9H2H8
HDVKDDYVFECEAGT

SUPT20H

331

Q8NEM7
KECLEKESRDYDVDH

SUGP2

181

Q8IX01
VDEERYDIEAKCLHN

TNNI1

76

P19237
TERKEVDEQIHACYA

SGSM1

641

Q2NKQ1
DYKQVEVTVHKGDEC

PLEC

951

Q15149
RDVEHYVGSDKEIDV

PHF8

181

Q9UPP1
GFVEYVVDRSVEHDK

PSMD5

436

Q16401
ASFLKHVCDEEEVEG

SLC4A4

11

Q9Y6R1
CYVEDTEAEKGREHV

TRANK1

951

O15050
VTEEDEGVYHCKATN

FLT1

721

P17948
SEVIEGYEIACRKAH

CCT8

126

P50990
YQCDRHKVIVEAEDR

TERB1

616

Q8NA31
YDEVEAEGYVKHDCV

USP11

756

P51784
RTHSEEELYVDRVCG

ZNF169

506

Q14929
KTEAVRCEYEDTHKA

PP2D1

271

A8MPX8