Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA4F EP400 SZT2 KIF26A FAM110A CEP192 PLXND1 GRIN2D EDC4 FAAP100 KCNH3 SND1 RPTOR CSPG4 DISP2 ARHGEF4 PLK3 MED13 AHNAK2	1.45e-08	1105	124	19	35748872
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	KLK14 ZNF318 CEP192 FAAP100 FSIP2 BBX MICAL2 RPTOR	1.72e-07	168	124	8	30631154
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	NUP88 ZNF318 FSIP2 ARID1B SND1 ELF2 AHNAK2	3.11e-07	123	124	7	26912792
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SPHKAP KNDC1 DISP2 CEP295 ZNF518B CCSER1	1.85e-06	102	124	6	11214970
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IFT140 EMC1 EP400 SZT2 KIF26A PLXND1 ARID1B RPTOR HPS4 FLRT3 MED13	3.27e-06	529	124	11	14621295
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	DDX17 EP400 NOP53 MUC16 ZNF318 CEP192 LYSMD4 PLXND1 PCF11 CNNM3 PTPN3 BBX PI4KB	4.41e-06	777	124	13	35844135
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CCHCR1 IFT140 DDX17 ATP5PO GPAA1 NUP88 FAM110A FAAP100 MMADHC BBX SND1 RPTOR PI4KB NKTR VPS51 CSPP1 SORL1	4.80e-06	1321	124	17	27173435
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	DMTF1 ZNF318 TERT STAT4 ZBTB44 BBX BAZ2A UHRF1 ELF2 ATF3 ZKSCAN4 NEUROG3 PHF13	6.70e-06	808	124	13	20412781
Pubmed	CCHCR1 interacts with EDC4, suggesting its localization in P-bodies.	CCHCR1 EDC4	1.26e-05	2	124	2	24858563
Pubmed	Urinary and serum soluble CD25 complements urinary soluble CD163 to detect active renal anti-neutrophil cytoplasmic autoantibody-associated vasculitis: a cohort study.	CD163 IL2RA	1.26e-05	2	124	2	29506265
Pubmed	Differential function of RNCAM isoforms in precise target selection of olfactory sensory neurons.	NCAM2 OR10A4	1.26e-05	2	124	2	12538518
Pubmed	CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells.	TRAF2 UHRF1	1.26e-05	2	124	2	38411080
Pubmed	Up-regulated serum levels of soluble CD25 and soluble CD163 in pediatric patients with SARS-CoV-2.	CD163 IL2RA	1.26e-05	2	124	2	35233677
Pubmed	Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole.	CEP192 CEP295	1.26e-05	2	124	2	27562453
Pubmed	Human transcription factor protein interaction networks.	ERCC4 ATP5PO EP400 NOP53 NUP88 ZNF318 CEP192 EDC4 MORC2 SKI STAT4 PCF11 ARID1B BBX ELF2 ZKSCAN4 SORL1	1.33e-05	1429	124	17	35140242
Pubmed	Genome-wide association analysis of age-at-onset in Alzheimer's disease.	DCHS2 ADAMTS9 ALPK3	2.90e-05	17	124	3	22005931
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CCHCR1 CEP192 CEP295 NKTR CSPP1	3.20e-05	101	124	5	24613305
Pubmed	SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.	TERT SND1	3.77e-05	3	124	2	33305480
Pubmed	GluN2D subunit-containing NMDA receptors control tissue plasminogen activator-mediated spatial memory.	GRIN2D PLAT	3.77e-05	3	124	2	22972996
Pubmed	Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells.	STAT4 IL2RA	3.77e-05	3	124	2	22888135
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	IFT140 TRAF2 EP400 ABCA12 ZNF318 SKI ZNF469 ARID1B BAZ2A RPTOR MAIP1 CEP295 VPS51 SORL1	4.64e-05	1116	124	14	31753913
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EMC1 SIK1 CEP192 EDC4 FSIP2 PTPN3 RPTOR PI4KB ARHGEF4 CSPP1 AHNAK2 CCSER1	6.20e-05	861	124	12	36931259
Pubmed	SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation.	SZT2 RPTOR	7.53e-05	4	124	2	36250465
Pubmed	Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP).	CNNM3 CNNM1	7.53e-05	4	124	2	12657465
Pubmed	STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus.	STAT4 IL2RA	7.53e-05	4	124	2	14660657
Pubmed	Comparison of Muscle Regeneration after BMSC-Conditioned Medium, Syngeneic, or Allogeneic BMSC Injection.	CD163 LY6H	7.53e-05	4	124	2	36139418
Pubmed	Molecular cloning and characterization of the mouse Acdp gene family.	CNNM3 CNNM1	7.53e-05	4	124	2	14723793
Pubmed	Purification, crystallization and preliminary crystallographic analysis of the CBS pair of the human metal transporter CNNM4.	CNNM3 CNNM1	7.53e-05	4	124	2	21393841
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	METTL3 EMC1 ATP5PO EP400 NOP53 FAM110A ZNF318 EDC4 MORC2 PLPP6 PCF11 BBX SND1 BAZ2A CRYBG1 MED13	8.71e-05	1497	124	16	31527615
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	EP400 CAST ZNF318 MORC2 USP16 PCF11 BAZ2A RPTOR AFF1 ELF2 MED13	1.07e-04	774	124	11	15302935
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	METTL3 EP400 EDC4 MORC2 BBX UHRF1 ELF2 ZKSCAN4 CSPP1 MED13	1.10e-04	645	124	10	25281560
Pubmed	ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells.	ADAMTS9 CSPG4	1.25e-04	5	124	2	20093484
Pubmed	UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold.	ERCC4 UHRF1	1.25e-04	5	124	2	25818288
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DDX17 EP400 NUP88 CAST ZNF318 EDC4 USP16 SND1 BAZ2A ELF2 AHNAK2 UBFD1	1.33e-04	934	124	12	33916271
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	DDX17 ATP5PO EP400 NOP53 CAST ZNF318 PCF11 ARID1B BBX BAZ2A ELF2 ZKSCAN4	1.62e-04	954	124	12	36373674
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	TMEM202 CNST KLHDC7B TERT ARID1B BBX BAZ2A AFF1	1.64e-04	431	124	8	33660365
Pubmed	Isolation of pancreatic progenitor cells with the surface marker of hematopoietic stem cells.	LY6H NEUROG3	1.87e-04	6	124	2	23316230
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	ERCC4 EP400 NUP88 ZNF318 PCF11 ARID1B SND1 NKTR	1.89e-04	440	124	8	34244565
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GPRASP1 DCHS2 TRAF2 CNST ENPP2 NCAM2 CMYA5 USP16 ZBTB44 ADAMTS9 MICAL2 HPS4 MAST1 MED13	2.04e-04	1285	124	14	35914814
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	EP400 NOP53 ZNF318 ARID1B BBX ELF2 ATF3	2.23e-04	339	124	7	30415952
Pubmed	TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.	TRAF2 RPTOR	2.62e-04	7	124	2	28489822
Pubmed	Molecular development of sensory maps: representing sights and smells in the brain.	NCAM2 OR10A4	2.62e-04	7	124	2	9988220
Pubmed	Genome-wide association study of alcohol dependence.	PECR CAST	2.62e-04	7	124	2	19581569
Pubmed	Interaction network of human early embryonic transcription factors.	EP400 NUP88 SKI ARID1B UHRF1 ELF2 ATF3	2.75e-04	351	124	7	38297188
Pubmed	Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis.	STAT4 IL2RA	3.48e-04	8	124	2	19565500
Pubmed	Roles of CHOP/GADD153 in endoplasmic reticulum stress.	TRAF2 ATF3	3.48e-04	8	124	2	14685163
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	EP400 SKI PCF11 ARID1B ELF2 MED13	4.14e-04	268	124	6	33640491
Pubmed	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	ARID1B MAIP1	4.47e-04	9	124	2	19176441
Pubmed	Wnt signaling specifies and patterns intestinal endoderm.	HOXD10 LY6H	4.47e-04	9	124	2	21854845
Pubmed	Axon fasciculation in the developing olfactory nerve.	NCAM2 OR10A4	4.47e-04	9	124	2	20723208
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TRAF2 MUC16 ARID1B PI4KB MAIP1 CEP295 ATF3 CSPP1 AHNAK2	4.86e-04	638	124	9	31182584
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	DMTF1 CCHCR1 ERCC4 CNST CAST ZNF318 CEP192 DUS3L ARID1B CRYBG1 AFF1 CEP295	5.13e-04	1084	124	12	11544199
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	DDX17 EP400 ZNF318 PCF11 BBX BAZ2A	5.51e-04	283	124	6	30585729
Pubmed	The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway.	TRAF2 RPTOR	5.57e-04	10	124	2	37081115
Pubmed	IL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelination.	STAT4 IL2RA	5.57e-04	10	124	2	21364747
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	DDX17 EP400 ZNF318 DPP3 EDC4 MORC2 PCF11 ARID1B SND1 ELF2 ATF3 ZKSCAN4	5.98e-04	1103	124	12	34189442
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EP400 CEP192 BAZ2A SPHKAP MAST1 DISP2 ARHGEF4	6.65e-04	407	124	7	12693553
Pubmed	CDK6 kinase activity is required for thymocyte development.	LY6H IL2RA	6.79e-04	11	124	2	21508411
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	DDX17 ATP5PO EP400 NUP88 ZNF318 SKI ZBTB44 BBX BAZ2A UHRF1 ELF2 ATF3 NKTR	7.40e-04	1294	124	13	30804502
Pubmed	Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.	CCHCR1 TERT	8.13e-04	12	124	2	21743467
Pubmed	Slits and Robo-2 regulate the coalescence of subsets of olfactory sensory neuron axons within the ventral region of the olfactory bulb.	NCAM2 OR10A4	8.13e-04	12	124	2	22981605
Pubmed	Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells.	STAT4 IL2RA	8.13e-04	12	124	2	33326784
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA4F PLXND1 FLRT3	8.61e-04	52	124	3	26633812
Pubmed	Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.	NCAM2 OR10A4	9.59e-04	13	124	2	20624980
Pubmed	Perivascular cells expressing annexin A5 define a novel mesenchymal stem cell-like population with the capacity to differentiate into multiple mesenchymal lineages.	CSPG4 LY6H	9.59e-04	13	124	2	15857912
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	DMTF1 METTL3 ABCA12 SND1 PLAT	1.05e-03	214	124	5	22199357
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	TMPRSS9 TRAF2 DDX17 SNHG12 SZT2 SIK1 DGKH GRIN2D PCF11 CSPG4 UHRF1	1.10e-03	1021	124	11	26760575
Pubmed	Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists.	EMC1 NEK10	1.12e-03	14	124	2	20095854
Pubmed	CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.	CEP192 CEP295	1.12e-03	14	124	2	32060285
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ERCC4 EP400 ZNF318 MORC2 ZNF518B	1.23e-03	222	124	5	37071664
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	IFT140 EP400 PLXND1 MED13	1.24e-03	130	124	4	12421765
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	ERCC4 EP400 FAAP100 ARID1B MAIP1 ATF3 MED13	1.24e-03	453	124	7	29656893
Pubmed	Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.	PCF11 MED13 AHNAK2	1.24e-03	59	124	3	28813667
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	DDX17 EP400 CAST EDC4 SND1 AHNAK2	1.26e-03	332	124	6	32786267
Pubmed	PDZ-Containing Proteins Targeted by the ACE2 Receptor.	PTPN3 MAST1	1.28e-03	15	124	2	34835087
Pubmed	Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.	ICAM2 CSPG4	1.28e-03	15	124	2	26630461
Pubmed	The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.	STAT4 IL2RA	1.28e-03	15	124	2	20219786
Pubmed	Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.	STAT4 IL2RA	1.28e-03	15	124	2	20498205
Pubmed	Leucine-rich repeat-containing protein 59 mediates nuclear import of cancerous inhibitor of PP2A in prostate cancer cells.	CEP192 CSPP1	1.46e-03	16	124	2	25833693
Pubmed	Exploration of 16 candidate genes identifies the association of IDE with Alzheimer's disease in Han Chinese.	GAPDHS SORL1	1.46e-03	16	124	2	20880607
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	SEMA4F KIF26A BBX MAST1 CEP295	1.52e-03	233	124	5	37704626
Pubmed	Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).	METTL3 CD163 STAT4	1.64e-03	65	124	3	32120844
Pubmed	SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis.	CSPG4 PLAT	1.66e-03	17	124	2	18667463
Pubmed	Protein phosphatase 1α interacting proteins in the human brain.	CNST NOP53 SORL1	1.79e-03	67	124	3	22321011
Pubmed	Dual Effect of Raptor on Neonatal β-Cell Proliferation and Identity Maintenance.	RPTOR NEUROG3	1.86e-03	18	124	2	31345937
Pubmed	On the integration of alcohol-related quantitative trait loci and gene expression analyses.	KCNJ9 SORL1	1.86e-03	18	124	2	15597075
Pubmed	The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map.	NCAM2 OR10A4	1.86e-03	18	124	2	26446231
Pubmed	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	DGKH ARID1B	1.86e-03	18	124	2	24068962
Pubmed	Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.	NCAM2 OR10A4	1.86e-03	18	124	2	20550939
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	PECR SZT2 USP16 VPS51	1.94e-03	147	124	4	29576527
Pubmed	Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.	CSPG4 LY6H	2.07e-03	19	124	2	28111199
Pubmed	Genome-wide association study of liver enzymes in korean children.	MMADHC ADAMTS9	2.07e-03	19	124	2	24124411
Pubmed	m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs.	METTL3 ARID1B	2.07e-03	19	124	2	36039295
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	EP400 ARID1B BAZ2A UHRF1	2.09e-03	150	124	4	28242625
Pubmed	KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.	SZT2 RPTOR	2.30e-03	20	124	2	28199306
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	EP400 ARID1B BAZ2A UHRF1	2.46e-03	157	124	4	30186101
Pubmed	A gene expression map of human chromosome 21 orthologues in the mouse.	ATP5PO SIK1 NCAM2 USP16	2.52e-03	158	124	4	12466855
Pubmed	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.	SEMA4F PLXND1	2.53e-03	21	124	2	36240771
Pubmed	Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development.	DISP2 NEUROG3	2.53e-03	21	124	2	20003319
Pubmed	FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification.	DDX17 EP400 MED13	2.77e-03	78	124	3	25720964
Interaction	NUP43 interactions	DDX17 EP400 SZT2 NOP53 NUP88 ZNF318 MORC2 FSIP2 ARID1B BBX SND1 BAZ2A ELF2 NKTR AHNAK2	6.35e-06	625	123	15	int:NUP43
Interaction	DEUP1 interactions	CCHCR1 DGKH CEP192 FAAP100 NKTR CSPP1	7.61e-06	77	123	6	int:DEUP1
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GPRASP1 DDX17 NEK10 DGKH STAT4 ARID1B NKTR	1.35e-06	197	124	7	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KLHDC7B STAT4 PLPP6 CNNM3 MICAL2 PI4KB MAST1	1.45e-06	199	124	7	26bb93347e6722abd174dfa62cab692ce2b7eb23
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	DDX17 ABCA12 DGKH STAT4 ARID1B NKTR	3.57e-06	147	124	6	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MORC2 PTPN3 HOXD10 KCNJ9 ALPK3 CCSER1	5.03e-06	156	124	6	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDX17 CMYA5 PTPN3 ARID1B CRYBG1 AFF1	8.23e-06	170	124	6	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	DDX17 DGKH STAT4 ARID1B CRYBG1 NKTR	1.18e-05	181	124	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNST SIK1 FAM110A PCF11 ATF3 PLK3	1.46e-05	188	124	6	5e13725136114e42d3b59647cf25e0f3c53abb54
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|390C / Donor, Lineage, Cell class and subclass (all cells)	TRAF2 SIK1 CEP192 RPTOR IL2RA	1.49e-05	111	124	5	dfbdeadad321392d359e6fb7112b28b043a4b874
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPRASP1 EP400 ENPP2 DGKH STAT4 NKTR	1.74e-05	194	124	6	3211d89440a6f4a9b3d4cfb755890816944242ec
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPRASP1 CNNM1 KCNJ9 MAST1 DISP2 LY6H	1.74e-05	194	124	6	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PECR NEK10 PTPN3 CRYBG1 SORL1 CCSER1	1.85e-05	196	124	6	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	PBMC-Mild-cDC_0\|Mild / Compartment, Disease Groups and Clusters	RNF19B PLXND1 SKI CD163 PLK3 SORL1	1.95e-05	198	124	6	fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ABCA12 TERT WDR87 GAPDHS	3.27e-05	65	124	4	acc541e5a0e4be5ddd5702f191185c5b405b8762
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ABCA12 TERT WDR87 GAPDHS	3.27e-05	65	124	4	b8ab40d75b4078123cdffec2f5326cff65f67578
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	LYSMD4 PLXND1 MORC2 GAPDHS ZKSCAN4	3.31e-05	131	124	5	88b3298110bc2333ffa202a3f41ac0d24e2308c7
Disease	viral hepatitis (is_marker_for)	TERT STAT4	4.83e-05	3	119	2	DOID:1884 (is_marker_for)
Disease	Metastatic melanoma	NEK10 SIK1 ALPK3 MAST1	6.81e-05	54	119	4	C0278883
Disease	rheumatoid arthritis, ACPA-negative rheumatoid arthritis	STAT4 IL2RA	1.60e-04	5	119	2	EFO_0000685, EFO_0009460
Disease	Juvenile pauciarticular chronic arthritis	STAT4 IL2RA	3.34e-04	7	119	2	C2931171
Disease	acute lymphoblastic leukemia (is_marker_for)	CAST TERT CSPG4	3.49e-04	34	119	3	DOID:9952 (is_marker_for)
Disease	Hereditary Motor and Sensory Neuropathy Type I	MORC2 HOXD10	4.44e-04	8	119	2	C0751036
Disease	Roussy-Levy Syndrome (disorder)	MORC2 HOXD10	4.44e-04	8	119	2	C0205713
Disease	Hantavirus hemorrhagic fever with renal syndrome (is_marker_for)	CD163 IL2RA	4.44e-04	8	119	2	DOID:11266 (is_marker_for)
Disease	Charcot-Marie-Tooth Disease, Type Ib	MORC2 HOXD10	4.44e-04	8	119	2	C0270912
Disease	Charcot-Marie-Tooth Disease, Type Ia (disorder)	MORC2 HOXD10	4.44e-04	8	119	2	C0270911
Disease	X-17676 measurement	TAS1R2 ACSM5	4.44e-04	8	119	2	EFO_0800785
Disease	Charcot-Marie-Tooth Disease	MORC2 HOXD10	1.04e-03	12	119	2	C0007959
Disease	mood disorder	FLRT3 SORL1	1.22e-03	13	119	2	EFO_0004247
Disease	Hereditary Motor and Sensory-Neuropathy Type II	MORC2 HOXD10	1.22e-03	13	119	2	C0270914
Disease	obesity (implicated_via_orthology)	DCHS2 PLXND1 STAT4 ADAMTS9 MED13	1.83e-03	215	119	5	DOID:9970 (implicated_via_orthology)
Disease	ovarian neoplasm	ERCC4 MUC16 TERT ATF3	2.16e-03	134	119	4	C0919267
Disease	Malignant neoplasm of ovary	ERCC4 MUC16 TERT ATF3	2.34e-03	137	119	4	C1140680
Disease	Uterine leiomyoma, estrogen-receptor positive breast cancer	NEK10 TERT	2.37e-03	18	119	2	EFO_1000649, HP_0000131
Disease	Sjogren's syndrome (is_implicated_in)	CAST STAT4	2.37e-03	18	119	2	DOID:12894 (is_implicated_in)
Disease	hearing loss	TMPRSS9 KLHDC7B ZNF318	2.54e-03	67	119	3	EFO_0004238
Disease	pulse pressure measurement, alcohol drinking	NEK10 ENPP2 ZNF318	2.88e-03	70	119	3	EFO_0004329, EFO_0005763
Disease	cortisol measurement	TMPRSS9 DGKH	2.92e-03	20	119	2	EFO_0005843
Disease	bipolar disorder, schizophrenia, response to lithium ion	ERCC4 MAIP1	2.92e-03	20	119	2	GO_0010226, MONDO_0004985, MONDO_0005090
Disease	pentachlorophenol measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022071
Disease	parathion measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022070
Disease	potassium chromate measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022072
Disease	mercuric chloride measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022068
Disease	heptachlor epoxide measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022067
Disease	methoxychlor measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022052
Disease	azinphos methyl measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022055
Disease	aldrin measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022054
Disease	dicofol measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022060
Disease	disulfoton measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022062
Disease	dieldrin measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022061
Disease	endrin measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022064
Disease	endosulfan measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022063
Disease	heptachlor measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022066
Disease	ethion measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022065
Disease	chlorpyrifos measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022057
Disease	cadmium chloride measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022056
Disease	diazinon measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022059
Disease	dibutyl phthalate measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0022058
Disease	environmental exposure measurement	MUC16 RPTOR MAIP1	3.24e-03	73	119	3	EFO_0008360
Disease	DDT metabolite measurement	MUC16 RPTOR MAIP1	3.37e-03	74	119	3	EFO_0007886

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEISTSAAPAARPAA	EP400	1441	Q96L91
SGTCRPDVSESPELR	BBX	226	Q8WY36
PPARDVAATLAVAVS	CSPG4	1681	Q6UVK1
AVAVSFEAACPQRPS	CSPG4	1691	Q6UVK1
ILDEPSTGVDPCSRR	ABCA12	1501	Q86UK0
VSVLVPDPTVSCLDD	BAZ2A	266	Q9UIF9
DETPVCIETETAPLR	FLRT3	491	Q9NZU0
FCVTSLDPDTLPAVA	CASTOR2	186	A6NHX0
PGCLPRSEEAVVTAS	ALPK3	971	Q96L96
CISAETVRGEAPSQP	ARHGEF4	41	Q9NR80
FVCPTSSDPLRTCAV	CMTR2	671	Q8IYT2
SLAPRVDAISAECPS	ACSM5	171	Q6NUN0
DEPRSRDETPLCTIA	ARID1B	1991	Q8NFD5
PVLVRASPSCSVDVT	CCSER1	221	Q9C0I3
SSPVRTCGPLTDEDV	DUS3L	276	Q96G46
DSTPCISVVALPLSE	DMTF1	66	Q9Y222
DETCLSTSEPSARVP	DISP2	1296	A7MBM2
RGEVPCTVTSASPLE	ATP5PO	136	P48047
PDITRETCSTLAESP	EDC4	831	Q6P2E9
VVSRINPESPADTCI	PTPN3	536	P26045
FEVPTPSCSARELAE	KCNJ9	326	Q92806
AARGPPSVCDLAVEV	KCNH3	256	Q9ULD8
SPCVAAPALDAFVER	KCNK6	51	Q9Y257
ESHVAAAPPDICSRT	MMADHC	41	Q9H3L0
VATRVDAICTHRPDP	MUC16	13231	Q8WXI7
DAEVCPTPARLATTE	NOP53	321	Q9NZM5
TPAVAEVRLPSATLC	MAIP1	26	Q8WWC4
APRLAVAVPAVTSAD	LYSMD4	271	Q5XG99
FPRASEDEVTCPTSA	NEUROG3	21	Q9Y4Z2
PRAASTESLVLTVPC	GPAA1	136	O43292
EPEPASRVCTVLVSR	NTSR2	186	O95665
RAVRPIEVTQACASP	KLK14	141	Q9P0G3
VRCVSDISDSPPTLV	HPS4	61	Q9NQG7
AEPCAFVVDTSVRRP	FSIP2	581	Q5CZC0
RAARTACFVEPAPDV	PLXND1	401	Q9Y4D7
TISRCLTPDAEARPD	NEK10	761	Q6ZWH5
PEEVSSVVCFLLSPA	PECR	236	Q9BY49
TSSVRDDPLEHCVSP	CSPP1	11	Q1MSJ5
IDLCDSPVSPAEASR	FAM110A	111	Q9BQ89
TVTDAPPECFLTLRD	DPP3	646	Q9NY33
AAVAVADTVRECPPV	KIF26A	251	Q9ULI4
VFSESVLPVCLATPE	PRSS38	161	A1L453
PRCPESLTRDTATEI	DGKH	1036	Q86XP1
PTRDPVATFLETCRE	FAAP100	671	Q0VG06
CIIASVPLAASPARA	NPTXR	21	O95502
QPSDTVCASVRITDP	LY6H	46	O94772
EEPVEIRQFSSCSPR	MAST1	696	Q9Y2H9
DAVSICLAISTPDAP	METTL3	96	Q86U44
PSTSECLRIEPDTTA	MORC2	886	Q9Y6X9
DSPPVIALVCADTSV	OR10A4	181	Q9H209
PPLSATCLVSITVDD	DCHS2	641	Q6V1P9
ERIDTPPACTEESIA	PCF11	1526	O94913
PSEERAAPVLSCEAA	FAM189A2	281	Q15884
VADESACATLPRPVA	ADAMTS9	1216	Q9P2N4
RTAPSTPVIRAEDCT	CMYA5	3801	Q8N3K9
PEERSCLAEVSVSSP	HOXD10	226	P28358
RTPEDRSDPDACTIS	HTR1A	176	P08908
ASEVSASAIVPCLSP	ATF3	11	P18847
ASAPVAAAVPTRESI	CCHCR1	726	Q8TD31
ESPTCLRDSRSPVEV	ELF2	106	Q15723
KAAAPAPVSEAVCRT	CAST	396	P20810
ASPEGRPESETSCLV	IL2RA	201	P01589
ESVRAPVEVAPCADV	CEP192	1551	Q8TEP8
PVEVAPCADVVTRLA	CEP192	1556	Q8TEP8
ARADLSCLVPATSVA	FAM98C	281	Q17RN3
CEIAPSSEQEVRPAA	KLHDC7B	136	Q96G42
SAPERPSAAEAIKVC	KNDC1	566	Q76NI1
CRFPVLPAESDAVTV	CRIPAK	406	Q8N1N5
ASAAVPRKAEVPCAA	CCDC177	46	Q9NQR7
DEAVLVCPDPSSRSL	EMC1	231	Q8N766
CVLLPSPTREAATVA	DDX17	11	Q92841
ERSPEAVGSECPSRV	CRYBG1	531	Q9Y4K1
RVPTPDVSVVDLTCR	GAPDHS	306	O14556
TRPTIPEESAVACIE	CD163	701	Q86VB7
APASCPVISDEDSHR	CEP295	561	Q9C0D2
PDNVLVFDPVCSRVA	SBK3	166	P0C264
SEPRLFVCEAVQETP	IFT140	656	Q96RY7
EVSSVPDHLTSCVRP	ENPP2	641	Q13822
PDHLTSCVRPDVRVS	ENPP2	646	Q13822
PGDSVERSVTCLPSA	CNST	21	Q6PJW8
EAPRRDTPTESSCAV	MICAL2	1086	O94851
ASPPLLCTREDVEVA	NUP88	501	Q99567
CRSTCSVEQEPDPSR	GPRASP1	1026	Q5JY77
SREAPTSCESLDVSP	SZT2	2886	Q5T011
TSCESLDVSPPGARE	SZT2	2891	Q5T011
REEVTCSVAPSGSLP	SPHKAP	576	Q2M3C7
RCPEDVSSSVLPSGD	SORL1	1041	Q92673
RLEISESRVPISCPE	RNF19B	151	Q6ZMZ0
LPPSFLAVCDTEEVS	SNHG12	6	Q9BXW3
PISEADSCLTRFAVP	SEMA4F	46	O95754
ICTPDRSSPAKVEET	NKTR	1131	P30414
PVCSVADSAPRADRA	FBXL18	421	Q96ME1
KAASVECISPVSPRA	SHC3	471	Q92529
EVSTRLSPLTAPCIV	SIK1B	476	A0A0B4J2F2
EVSTRLSPLTAPCIV	SIK1	476	P57059
SPATETVPAFSERTC	SND1	426	Q7KZF4
TIECRVPTVEPLDSL	ICAM2	131	P13598
PVTEEDPILSSFSRC	MED13	46	Q9UHV7
CENFDTTSVPARIPE	PI4KB	406	Q9UBF8
AAAVSRAPEPLATCT	SKI	436	P12755
PAAPVRVVETSALLC	RIOX1	136	Q9H6W3
SLLSDPIPEVRCAAV	RPTOR	606	Q8N122
PSCRKPDAEVLTVES	AHNAK2	5161	Q8IVF2
CASVTDSAPERELSP	AFF1	186	P51825
FVDPDDCTPLLTVTR	CNNM1	486	Q9NRU3
VDPEDCTPLSTITRF	CNNM3	371	Q8NE01
ARREVESLPAVCPSD	TRAF2	96	Q12933
DRLPISSCVTVPDLT	PLK3	321	Q9H4B4
DIASSVPLPVSDRCF	PHF13	76	Q86YI8
FPVTPVSTLCAEARE	VPS51	556	Q9UID3
CPVSETFARLCPVSE	nan	16	Q6ZQT0
CPVSETFARLCPVSE	nan	26	Q6ZQT0
CPVSETFARLCPVSE	nan	36	Q6ZQT0
PDASSTVPSLCTEAR	nan	51	Q96NJ1
TVATEAPARPVNCLE	UBFD1	21	O14562
QESSVVRTVCLPPAD	PLAT	421	P00750
VAPLLAAPTAVRSCS	nan	16	Q6ZSR3
VPIDDSSETLEPVCR	USP16	11	Q9Y5T5
DAEVVCRVSSSPAPA	NCAM2	131	O15394
SSQPCEVSRPTERGD	STAT4	676	Q14765
SPVSSECSVVERTIP	ZBTB44	161	Q8NCP5
VPRTTKEVPALDAAC	TMPRSS9	11	Q7Z410
TRTDPDDPKITIVSC	TAS1R2	706	Q8TE23
VDPTCARLRASESPV	PLPP6	51	Q8IY26
TEFTEALRSPPAACA	ZNF469	1211	Q96JG9
RDEPCSSTSRPALEE	UHRF1	166	Q96T88
EASALTAEVRAPCSP	ZKSCAN4	31	Q969J2
REISSSPESCPEEIK	ERCC4	516	Q92889
TSRSPACDENVTVIP	TMEM202	216	A6NGA9
SSEVLVFDTTRCPCP	WDR87	391	Q6ZQQ6
TVRPAAETELVPCSL	nan	66	Q96M66
SPCLPDLVDFVTRTS	ZNF318	2166	Q5VUA4
CVVSPARPAEEATSL	TERT	271	O14746
ETPSCVVTCPDLSRR	ZP4	451	Q12836
EATCEAPVSIPCSER	ZNF518B	791	Q9C0D4
PLPEAVSSAAVASCA	KLHL35	426	Q6PF15
EPADPISGTCIRDSV	GRIN2D	446	O15399