Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

LTK EFNB3

1.91e-0365202GO:0004714
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

LTK EFNB3

3.24e-0385202GO:0019199
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

ALPK3 LTK PFKL EFNB3

4.85e-03709204GO:0016773
GeneOntologyMolecularFunctionkinase activity

ALPK3 LTK PFKL EFNB3

6.31e-03764204GO:0016301
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

LTK EFNB3

9.13e-03145202GO:0004713
GeneOntologyCellularComponentside of membrane

RGMA FCN1 IL6R CAPN2 CARMIL2 ITGA7

1.24e-04875206GO:0098552
GeneOntologyCellularComponentexternal side of plasma membrane

FCN1 IL6R CAPN2 ITGA7

1.33e-03519204GO:0009897
GeneOntologyCellularComponentcell surface

RGMA FCN1 IL6R CAPN2 ITGA7

3.34e-031111205GO:0009986
GeneOntologyCellularComponentendopeptidase complex

FCN1 CAPN2

4.23e-03102202GO:1905369
Pubmed

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

EIF4H CAPN2 PFKL

4.43e-0426320312665801
Pubmed

Signal peptide prediction based on analysis of experimentally verified cleavage sites.

FCN1 EFNB3 ITGA7

4.48e-0426420315340161
Pubmed

A genome-wide association study identifies protein quantitative trait loci (pQTLs).

CDAN1 IL6R

5.63e-046120218464913
CytobandEnsembl 112 genes in cytogenetic band chr15q15

CDAN1 LTK

1.86e-03147202chr15q15
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

ZNF219 CARMIL2 EFNB3

3.03e-05137203b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IL6R CAPN2 LTK

3.59e-05145203fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RGMA FCN1 EFNB3

4.13e-05152203072daae0deb6cb92f126e4566f1d264cda9ed157
ToppCellControl-CD4+_T|World / Disease group and Cell class

EIF4H IL6R ZNF219

5.66e-05169203e330d85bd37a1bd1c3d8d29ddd8a2c1020a62a83
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDAN1 FCN1 IL6R

5.97e-05172203a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CDAN1 FCN1 IL6R

6.28e-05175203f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC-DC3|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

7.17e-05183203c6cac433ea7a3d60728efdc7051e09e01bb3ade5
ToppCell(11)_FOXN4+-(0)_Reference|(11)_FOXN4+ / shred by cell type by condition

CLEC16A CCDC9 ITGA7

8.27e-05192203ef06f96b934dd05b40025f8215b6d919d3a17045
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC3|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

8.27e-051922030e0fbc0bc004dea0db8ccbe81738ab50c0685883
ToppCellControl-Lymphoid-CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

SYDE2 IL6R ZNF219

8.66e-051952038679a122fe796b1eddef82460e985b3fd3b3a2a5
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-DC3|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

8.79e-05196203d4e5b55a32d9c04c6b2ca7806a0d96231918761f
ToppCell10x3'2.3-week_17-19-Myeloid_monocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.06e-05198203100091c91fde604daf110f20b44505f240f93ae8
ToppCell10x3'2.3-week_14-16-Myeloid_monocytic-monocyte-promonocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.06e-05198203ff634a17195d06a8614ed1c6564937d10ca5c00d
ToppCell10x3'2.3-week_12-13-Myeloid_monocytic-monocyte-promonocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.06e-05198203b0747b0607d67a480a0a563b775007975c3eab32
ToppCellControl-CD4+_T|Control / Disease group and Cell class

EIF4H IL6R ZNF219

9.06e-051982032682eea9b34cfc7e82891c1f1117d3c874107af6
ToppCell10x3'2.3-week_17-19-Myeloid_monocytic-monocyte-promonocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.06e-05198203a11de3836fc1575bec5f6c701836fe2fb5a1027a
ToppCell10x3'2.3-week_17-19-Myeloid_monocytic-monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.06e-0519820373e9ada6998c09ae3a3a66e920b28694b7f9cf6b
ToppCell10x3'2.3-week_14-16-Myeloid_monocytic-monocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.06e-05198203eae8c29d68cc94bfbd15e487ad855639c2a4fcc9
ToppCell10x3'2.3-week_14-16-Myeloid_monocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.06e-051982032f94fb4a1719d5adddb4fd3dfaf099ee2b642011
ToppCell10x5'v1-week_17-19-Myeloid_monocytic-monocyte-promonocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.19e-05199203b725a9c9bdc307641958a8f3ab2f6af9e7a0163d
ToppCell10x3'2.3-week_17-19-Myeloid_monocytic-monocyte-CD14_monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.19e-0519920350a30d5ee99e51743a0dd60144fc341ff68da9af
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte-promonocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.19e-05199203f7661a386224682e1d79cc9949204d05c0dfe324
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.19e-051992037f5d47e49776114d9f4a42017fead9eeb415a94c
ToppCell10x5'v1-week_17-19-Myeloid_monocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.19e-05199203aa30a57c0907d012942e7babdbff6ea4d01d7798
ToppCell10x5'v1-week_14-16-Myeloid_monocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.19e-051992035caaf66b6cddcc8f0d0aee3c9ba80d02075e87e5
ToppCell10x5'v1-week_17-19-Myeloid_monocytic-monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.19e-051992037e5a56bb2ac441a8fa4ad0b928f9c0c82d128190
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RGMA SYDE2 ITGA7

9.33e-05200203be46efc899d06c55ee297bee3126f69bcdb2048b
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte-CD14_monocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.33e-05200203f65837b51bce94c08125b1a2e1a696a15267f64b
ToppCell10x5'v1-week_17-19-Myeloid_monocytic-monocyte-CD14_monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCN1 IL6R CAPN2

9.33e-0520020307197f95282ee607db17b92fea1376051e65fc50
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RGMA SYDE2 ITGA7

9.33e-052002035ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
DrugNiridazole [61-57-4]; Down 200; 18.6uM; HL60; HT_HG-U133A

CCDC9 CAPN2 EFNB3 ITGA7

2.32e-051962042440_DN
DrugVitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A

ALPK3 ZNF219 CAPN2 ITGA7

2.36e-051972043798_DN
Diseasesciatic neuropathy (biomarker_via_orthology)

RGMA IL6R CAPN2

4.01e-0599203DOID:11446 (biomarker_via_orthology)
Diseasetype 1 diabetes mellitus

RGMA CLEC16A IL6R

5.60e-04242203MONDO_0005147
Diseasemultiple sclerosis (is_implicated_in)

RGMA CLEC16A

1.11e-0373202DOID:2377 (is_implicated_in)
Diseaseage of onset of asthma

CLEC16A LTK

1.30e-0379202OBA_2001001
Diseaseasthma, Eczema, allergic rhinitis

CLEC16A IL6R

3.02e-03121202EFO_0005854, HP_0000964, MONDO_0004979
Diseasesleep duration, high density lipoprotein cholesterol measurement

RGMA CARMIL2

3.02e-03121202EFO_0004612, EFO_0005271
Diseasehip bone mineral density

RGMA FCN1

3.27e-03126202EFO_0007702
Diseaserespiratory system disease

CLEC16A IL6R

4.30e-03145202EFO_0000684
DiseaseEczema, allergic rhinitis

CLEC16A IL6R

9.21e-03215202EFO_0005854, HP_0000964
Diseaseatopic eczema

CLEC16A IL6R

1.25e-02252202EFO_0000274
DiseaseAlzheimer's disease (is_marker_for)

IL6R CAPN2

1.29e-02257202DOID:10652 (is_marker_for)
Diseaseallergic disease

CLEC16A IL6R

1.30e-02258202MONDO_0005271

Protein segments in the cluster

PeptideGeneStartEntry
MSCRGRGAGGRWNST

CASTOR3

1

Q8NAP1
GWMTGRADWRAGRGG

CARMIL2

391

Q6F5E8
GAMGSRRAPSRGWGA

ALPK3

201

Q96L96
AWGMRRAAAGAGGAR

ANKRD60

6

Q9BZ19
SWVSGSSGRSGGFMR

CDAN1

811

Q8IWY9
RGMGSSRESRGGWDS

EIF4H

136

Q15056
AMDGSEGVPGSRRWA

LTK

191

P29376
AGWLGRGGSMLGTKR

PFKL

456

P17858
SRWPRRGGSGAMAEA

H1-7

11

Q75WM6
DGGGWTVFQRRMDGS

FCN1

151

O00602
AAGSHPSRWAGMGRR

IL6R

66

P08887
GRAGMGRASRSWEGS

CCDC9

101

Q9Y3X0
TGGPSGRSGHRMVAW

KLHDC4

171

Q8TBB5
MAGARSRDPWGASGI

ITGA7

1

Q13683
MDGNWRRGSTAGGCR

CAPN2

361

P17655
GVAGAGGAMCWRRRR

EFNB3

241

Q15768
PRGGRMDGWSGDRAR

SYDE2

121

Q5VT97
TGRAGWMGMGRGAGR

RGMA

11

Q96B86
WMGMGRGAGRSALGF

RGMA

16

Q96B86
MFGRSRSWVGGGHGK

CLEC16A

1

Q2KHT3
ITGWGSVREGGSMAR

TMPRSS9

951

Q7Z410
GMGAVSWSESRAGER

ZNF219

41

Q9P2Y4