Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium:sodium antiporter activity	SLC3A2 SLC24A4 SLC24A2	1.51e-05	10	102	3	GO:0005432
GeneOntologyMolecularFunction	calcium:monoatomic cation antiporter activity	SLC3A2 SLC24A4 SLC24A2	3.57e-05	13	102	3	GO:0015368
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	ITGAV RYR2 SLC3A2 ITPR2 SLC24A4 SLC24A2	1.25e-04	151	102	6	GO:0015085
GeneOntologyMolecularFunction	calcium, potassium:sodium antiporter activity	SLC24A4 SLC24A2	2.56e-04	5	102	2	GO:0008273
GeneOntologyMolecularFunction	calcium channel activity	ITGAV RYR2 ITPR2 SLC24A4 SLC24A2	5.26e-04	129	102	5	GO:0005262
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	BEST2 RYR2 ITPR2	6.32e-04	33	102	3	GO:0005217
MousePheno	abnormal chromosome number	RANBP2 RGPD8 APC MAD2L1BP CDC25A NIPBL	1.99e-05	86	91	6	MP:0004023
MousePheno	abnormal respiratory motile cilium physiology	AK7 CFAP54 ODAD3 DNAH11	3.52e-05	29	91	4	MP:0011055
MousePheno	aneuploidy	RANBP2 RGPD8 APC MAD2L1BP CDC25A	4.67e-05	61	91	5	MP:0004024
MousePheno	impaired mucociliary clearance	MUC5B AK7 CFAP54	7.28e-05	13	91	3	MP:0010752
Domain	Ran_BP1	RANBP2 RGPD8 RGPD5	3.16e-05	12	100	3	PF00638
Domain	RANBD1	RANBP2 RGPD8 RGPD5	3.16e-05	12	100	3	PS50196
Domain	RanBD	RANBP2 RGPD8 RGPD5	4.10e-05	13	100	3	SM00160
Domain	Ran_bind_dom	RANBP2 RGPD8 RGPD5	4.10e-05	13	100	3	IPR000156
Domain	PAN_AP	MST1 MST1L	2.81e-04	5	100	2	SM00473
Domain	K/Na/Ca-exchanger	SLC24A4 SLC24A2	2.81e-04	5	100	2	IPR004481
Domain	RIH_assoc-dom	RYR2 ITPR2	4.20e-04	6	100	2	IPR013662
Domain	Ins145_P3_rec	RYR2 ITPR2	4.20e-04	6	100	2	PF08709
Domain	RIH_assoc	RYR2 ITPR2	4.20e-04	6	100	2	PF08454
Domain	RIH_dom	RYR2 ITPR2	4.20e-04	6	100	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 ITPR2	4.20e-04	6	100	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR2	4.20e-04	6	100	2	IPR015925
Domain	-	RYR2 ITPR2	4.20e-04	6	100	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 ITPR2	4.20e-04	6	100	2	PF01365
Domain	Pan_app	MST1 MST1L	5.86e-04	7	100	2	IPR003609
Domain	PAN	MST1 MST1L	5.86e-04	7	100	2	PS50948
Domain	PAN_1	MST1 MST1L	5.86e-04	7	100	2	PF00024
Domain	NaCa_Exmemb	SLC24A4 SLC24A2	9.97e-04	9	100	2	IPR004837
Domain	Na_Ca_ex	SLC24A4 SLC24A2	9.97e-04	9	100	2	PF01699
Domain	MIR	RYR2 ITPR2	1.24e-03	10	100	2	PF02815
Domain	MIR_motif	RYR2 ITPR2	1.24e-03	10	100	2	IPR016093
Domain	MIR	RYR2 ITPR2	1.24e-03	10	100	2	PS50919
Domain	MIR	RYR2 ITPR2	1.24e-03	10	100	2	SM00472
Domain	TPR-contain_dom	RANBP2 RGPD8 PTPN23 ZC3H7B RGPD5	1.28e-03	150	100	5	IPR013026
Domain	TPR_1	RANBP2 RGPD8 ZC3H7B RGPD5	1.39e-03	90	100	4	IPR001440
Domain	TPR_1	RANBP2 RGPD8 ZC3H7B RGPD5	1.39e-03	90	100	4	PF00515
Domain	Grip	RGPD8 RGPD5	1.51e-03	11	100	2	SM00755
Domain	GRIP	RGPD8 RGPD5	1.51e-03	11	100	2	PF01465
Domain	GRIP_dom	RGPD8 RGPD5	1.81e-03	12	100	2	IPR000237
Domain	GRIP	RGPD8 RGPD5	1.81e-03	12	100	2	PS50913
Domain	TPR_REGION	RANBP2 RGPD8 PTPN23 ZC3H7B RGPD5	1.94e-03	165	100	5	PS50293
Domain	TPR	RANBP2 RGPD8 PTPN23 ZC3H7B RGPD5	1.94e-03	165	100	5	PS50005
Domain	Gal_mutarotase_SF_dom	MGAM BEST2	3.66e-03	17	100	2	IPR011013
Domain	Kringle_CS	MST1 MST1L	3.66e-03	17	100	2	IPR018056
Domain	KRINGLE_1	MST1 MST1L	3.66e-03	17	100	2	PS00021
Domain	KR	MST1 MST1L	3.66e-03	17	100	2	SM00130
Domain	Kringle	MST1 MST1L	3.66e-03	17	100	2	IPR000001
Domain	KRINGLE_2	MST1 MST1L	3.66e-03	17	100	2	PS50070
Domain	Kringle	MST1 MST1L	3.66e-03	17	100	2	PF00051
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RANBP2 RGPD8 RGPD5	9.78e-08	4	102	3	9480752
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PDE2A ARHGAP23 SH3GL1 SH3KBP1 APC NFASC IDH2 VIRMA SLC3A2 ITPR2 MAPRE3 APPL2 LRIG1 SLC24A2 LRRC7 ALDH1B1 PCM1 DNAH11	1.75e-07	1431	102	18	37142655
Pubmed	EB/RP gene family encodes tubulin binding proteins.	APC MAPRE3 RP1	2.44e-07	5	102	3	10188731
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	FNDC3B RANBP2 ORC3 ACAD9 RCN2 APC UFL1 VIRMA SLC3A2 FAM83B MSH6 SEPTIN3 APPL2 ARHGEF9 LTN1 ZFHX3 ZC3H7B NIPBL	3.38e-07	1497	102	18	31527615
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RANBP2 XRN2 ACAD9 UGGT1 SH3GL1 RCN2 UFL1 IDH2 HMOX2 SLC3A2 ITPR2 MSH6 LTN1 MLLT11 ALDH1B1 GCN1 PCM1	9.64e-07	1440	102	17	30833792
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RANBP2 RGPD8 SH3GL1 SH3KBP1 APBA2 APC IDH2 HMOX2 RYR2 SLC3A2 SEPTIN3 LRRC7 ALDH1B1 GCN1 PCM1	1.19e-06	1139	102	15	36417873
Pubmed	Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.	UGGT1 RCN2 MSH6 LTN1 GCN1 PCM1	1.94e-06	125	102	6	36030824
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	RANBP2 UGGT1 PTPN23 VIRMA SLC3A2 N4BP2L2 GCN1	2.33e-06	202	102	7	24639526
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 RANBP2 RGPD8 APC ZFHX4 ZNF644 ZFHX3 GCN1 PCM1	4.10e-06	418	102	9	34709266
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RANBP2 RGPD8 NFASC	6.86e-06	13	102	3	31427429
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RANBP2 RGPD8 ORC3 SH3KBP1 RCN2 APC MAD2L1BP FAM83B ZNF644 C1orf52 GCN1 NIPBL PCM1 RGPD5	7.19e-06	1155	102	14	20360068
Pubmed	MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion.	MUC16 NRP2	8.52e-06	2	102	2	35533267
Pubmed	Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.	MST1 MST1L	8.52e-06	2	102	2	8393443
Pubmed	MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.	MST1 MST1L	8.52e-06	2	102	2	27609031
Pubmed	Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model.	MST1 MST1L	8.52e-06	2	102	2	24980820
Pubmed	m6A RNA modification and its writer/reader VIRMA/YTHDF3 in testicular germ cell tumors: a role in seminoma phenotype maintenance.	VIRMA YTHDF3	8.52e-06	2	102	2	30866959
Pubmed	Intestinal epithelial cell-specific CD98 expression regulates tumorigenesis in Apc(Min/+) mice.	APC SLC3A2	8.52e-06	2	102	2	22641098
Pubmed	Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein.	MST1 MST1L	8.52e-06	2	102	2	10728827
Pubmed	Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.	MST1 MST1L	8.52e-06	2	102	2	16961763
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	8.52e-06	2	102	2	10873665
Pubmed	Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.	APC LRIG1	8.52e-06	2	102	2	24833705
Pubmed	Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice.	MST1 MST1L	8.52e-06	2	102	2	39253972
Pubmed	Mitochondrial calcium overload is a key determinant in heart failure.	RYR2 ITPR2	8.52e-06	2	102	2	26217001
Pubmed	Cerebral ischemia-reperfusion is modulated by macrophage-stimulating 1 through the MAPK-ERK signaling pathway.	MST1 MST1L	8.52e-06	2	102	2	32017081
Pubmed	Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.	MST1 MST1L	8.52e-06	2	102	2	24409221
Pubmed	Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.	MST1 MST1L	8.52e-06	2	102	2	8340069
Pubmed	Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.	MST1 MST1L	8.52e-06	2	102	2	9486989
Pubmed	Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice.	MST1 MST1L	8.52e-06	2	102	2	33887258
Pubmed	HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.	MST1 MST1L	8.52e-06	2	102	2	25938541
Pubmed	Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway.	MST1 MST1L	8.52e-06	2	102	2	29760744
Pubmed	Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.	RYR2 ITPR2	8.52e-06	2	102	2	28158491
Pubmed	Mst1 deletion reduces hyperglycemia-mediated vascular dysfunction via attenuating mitochondrial fission and modulating the JNK signaling pathway.	MST1 MST1L	8.52e-06	2	102	2	31206688
Pubmed	Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.	DCHS2 FAT4	8.52e-06	2	102	2	15003449
Pubmed	Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy.	MST1 MST1L	8.52e-06	2	102	2	30708325
Pubmed	Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.	MST1 MST1L	8.52e-06	2	102	2	27696525
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CASP8AP2 XRN2 RGPD8 APC FAM83B MST1 ZNF644 SLFN11 YTHDF3 PCM1	9.35e-06	588	102	10	38580884
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RGPD8 UGGT1 RCN2 APC HMOX2 SLC3A2 ITPR2 MEX3A C1orf52 YTHDF3 PCM1	1.06e-05	733	102	11	34672954
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RANBP2 UGGT1 RCN2 PTPN23 SLC3A2 ITPR2 MSH6 LTN1 MLLT11 SLFN11 HERC1 CDC25A GCN1	1.24e-05	1049	102	13	27880917
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	RANBP2 SH3GL1 APBA2 APC FAM83B LRRC7 GCN1	1.31e-05	263	102	7	34702444
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	FAT4 ORC3 MUC16 VIRMA RYR2 SLC3A2 HFM1 SLFN11 NIPBL DNAH11	1.89e-05	638	102	10	31182584
Pubmed	Assignment of 22 loci in the rat by somatic hybrid and linkage analysis.	APC MST1 MST1L	1.94e-05	18	102	3	8268657
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	DENND4A APC VIRMA CDC25A GCN1 PCM1	2.14e-05	190	102	6	15161933
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	FNDC3B ARHGAP23 ACAD9 UGGT1 DDR2 RCN2 PTPN23 IDH2 HMOX2 ITGAV SLC3A2 NRP2 FAP LRIG1 CARS2	2.16e-05	1451	102	15	30550785
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	UGGT1 HMOX2 ITPR2 MSH6 HERC1 GCN1 PCM1	2.19e-05	285	102	7	32838362
Pubmed	Identification and Characterization of K(+)-Dependent Na(+)-Ca(2+) Exchange Transport in Pigmented MEB4 Cells Mediated by NCKX4.	SLC24A4 SLC24A2	2.55e-05	3	102	2	27093457
Pubmed	The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.	MST1 MST1L	2.55e-05	3	102	2	10225971
Pubmed	Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.	MST1 MST1L	2.55e-05	3	102	2	38430683
Pubmed	TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1.	MST1 MST1L	2.55e-05	3	102	2	26698664
Pubmed	Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins.	APC MSH6	2.55e-05	3	102	2	19029948
Pubmed	Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction.	MST1 MST1L	2.55e-05	3	102	2	17395874
Pubmed	Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement.	MST1 MST1L	2.55e-05	3	102	2	27496379
Pubmed	Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function.	MST1 MST1L	2.55e-05	3	102	2	12606483
Pubmed	Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice.	MST1 MST1L	2.55e-05	3	102	2	36623453
Pubmed	CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia-reperfusion injury via autophagic status.	MST1 MST1L	2.55e-05	3	102	2	38288506
Pubmed	The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.	MST1 MST1L	2.55e-05	3	102	2	8545120
Pubmed	Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.	MST1 MST1L	2.55e-05	3	102	2	25049204
Pubmed	Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.	APC LRIG1	2.55e-05	3	102	2	31813825
Pubmed	Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development.	MST1 MST1L	2.55e-05	3	102	2	1832957
Pubmed	Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease.	MST1 MST1L	2.55e-05	3	102	2	25183307
Pubmed	MST1 mediates neuronal loss and cognitive deficits: A novel therapeutic target for Alzheimer's disease.	MST1 MST1L	2.55e-05	3	102	2	35525373
Pubmed	MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice.	MST1 MST1L	2.55e-05	3	102	2	27510910
Pubmed	The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.	APC MSH6	2.55e-05	3	102	2	11691815
Pubmed	Hippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity.	MST1 MST1L	2.55e-05	3	102	2	38898027
Pubmed	WASP and Mst1 coregulate B-cell development and B-cell receptor signaling.	MST1 MST1L	2.55e-05	3	102	2	32045478
Pubmed	Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2.	MST1 MST1L	2.55e-05	3	102	2	27940445
Pubmed	Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.	MST1 MST1L	2.55e-05	3	102	2	12538524
Pubmed	SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions.	APC LRIG1	2.55e-05	3	102	2	37166989
Pubmed	Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes.	MST1 MST1L	2.55e-05	3	102	2	19339990
Pubmed	DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.	MUC16 MUC5B	2.55e-05	3	102	2	27230679
Pubmed	Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition.	MST1 MST1L	2.55e-05	3	102	2	30063115
Pubmed	Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury.	MST1 MST1L	2.55e-05	3	102	2	27218122
Pubmed	Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.	MST1 MST1L	2.55e-05	3	102	2	24852423
Pubmed	Transfer of Functional Cargo in Exomeres.	APC LRIG1	2.55e-05	3	102	2	30956133
Pubmed	Macrophage-stimulating protein cooperates with erythropoietin to induce colony formation and MAP kinase activation in primary erythroid progenitor cells.	MST1 MST1L	2.55e-05	3	102	2	12804176
Pubmed	Hippo Kinase MST1-Mediated Cell Metabolism Reprograms the Homeostasis and Differentiation of Granulocyte Progenitor Cells.	MST1 MST1L	2.55e-05	3	102	2	37184367
Pubmed	Combination of melatonin and irisin ameliorates lipopolysaccharide-induced cardiac dysfunction through suppressing the Mst1-JNK pathways.	MST1 MST1L	2.55e-05	3	102	2	31976559
Pubmed	Blood vessel epicardial substance reduces LRP6 receptor and cytoplasmic β-catenin levels to modulate Wnt signaling and intestinal homeostasis.	APC LRIG1	2.55e-05	3	102	2	30689807
Pubmed	Over-expressed MST1 impaired spatial memory via disturbing neural oscillation patterns in mice.	MST1 MST1L	2.55e-05	3	102	2	32468668
Pubmed	Nicorandil alleviates myocardial injury and post-infarction cardiac remodeling by inhibiting Mst1.	MST1 MST1L	2.55e-05	3	102	2	29127009
Pubmed	Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.	MST1 MST1L	2.55e-05	3	102	2	27465533
Pubmed	The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision.	SLC24A4 SLC24A2	2.55e-05	3	102	2	28650316
Pubmed	Suramin protects hepatocytes from LPS-induced apoptosis by regulating mitochondrial stress and inactivating the JNK-Mst1 signaling pathway.	MST1 MST1L	2.55e-05	3	102	2	30771091
Pubmed	MST1 mediates the N-methyl-D-aspartate-induced excitotoxicity in mouse cortical neurons.	MST1 MST1L	2.55e-05	3	102	2	34967918
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	XRN2 SH3KBP1 APBA2 APC RGPD5	2.87e-05	120	102	5	31413325
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RANBP2 ACAD9 UGGT1 SH3GL1 RCN2 PTPN23 SLC3A2 MSH6 LTN1 CDC25A GCN1 PCM1	2.91e-05	974	102	12	28675297
Pubmed	RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.	RYR2 ITPR2 DHH	3.13e-05	21	102	3	31712577
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	RANBP2 XRN2 ORC3 ACAD9 UGGT1 SH3GL1 APBA2 RCN2 SLC3A2 MSH6 RNF220 TBCK ALDH1B1 TUBAL3	3.58e-05	1335	102	14	29229926
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	ARHGAP23 APC NFASC ITPR2 MAPRE3 APPL2 LRRC7 TUBAL3	4.07e-05	430	102	8	32581705
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	RANBP2 XRN2 PTPN23 IDH2 VIRMA MSH6 LTN1 ZC3H7B GCN1 NIPBL	4.33e-05	704	102	10	29955894
Pubmed	Inhibition of TLR4-induced IκB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein.	MST1 MST1L	5.09e-05	4	102	2	21078906
Pubmed	Hyperglycemia-Induced Overexpression of PH Domain Leucine-Rich Repeat Protein Phosphatase 1 (PHLPP1) Compromises the Cardioprotective Effect of Ischemic Postconditioning Via Modulation of the Akt/Mst1 Pathway Signaling.	MST1 MST1L	5.09e-05	4	102	2	35715527
Pubmed	Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.	MST1 MST1L	5.09e-05	4	102	2	25074980
Pubmed	MST1 deficiency promotes B cell responses by CD4+ T cell-derived IL-4, resulting in hypergammaglobulinemia.	MST1 MST1L	5.09e-05	4	102	2	28527887
Pubmed	Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.	MST1 MST1L	5.09e-05	4	102	2	25133611
Pubmed	Nup358 interacts with APC and plays a role in cell polarization.	RANBP2 APC	5.09e-05	4	102	2	19654215
Pubmed	The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes.	MST1 MST1L	5.09e-05	4	102	2	22412158
Pubmed	Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice.	MST1 MST1L	5.09e-05	4	102	2	26903296
Pubmed	Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis.	MST1 MST1L	5.09e-05	4	102	2	23527007
Pubmed	MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS.	MST1 MST1L	5.09e-05	4	102	2	23818595
Pubmed	Mammalian sterile 20-like kinase 1 suppresses lymphoma development by promoting faithful chromosome segregation.	MST1 MST1L	5.09e-05	4	102	2	22926556
Interaction	C2CD4B interactions	FAT4 APBA2 APC HERC1 ALPK2	2.79e-06	44	102	5	int:C2CD4B
Interaction	NUP43 interactions	CASP8AP2 RANBP2 XRN2 RGPD8 APC VIRMA RYR2 RNF220 ZNF644 EPC1 ZFHX3 SLFN11 NIPBL RGPD5	3.17e-06	625	102	14	int:NUP43
Interaction	ADAR interactions	RANBP2 XRN2 UFL1 VIRMA MSH6 MEX3A GCN1 NIPBL TUBAL3	1.49e-05	286	102	9	int:ADAR
Interaction	CDKL5 interactions	RANBP2 SH3KBP1 APC VIRMA LRRC7 PCM1	2.36e-05	113	102	6	int:CDKL5
Interaction	SH3D19 interactions	SH3GL1 SH3KBP1 PTPN23 VIRMA MAPRE3	2.62e-05	69	102	5	int:SH3D19
Interaction	UNC93B1 interactions	BEST2 ACAD9 UGGT1 RCN2 UFL1 HMOX2 ITPR2 MSH6 LTN1 GCN1	5.05e-05	417	102	10	int:UNC93B1
Interaction	KCTD13 interactions	PDE2A ARHGAP23 SH3GL1 SH3KBP1 APBA2 APC NFASC IDH2 VIRMA SLC3A2 ITPR2 MAPRE3 APPL2 LRIG1 SLC24A2 LRRC7 ALDH1B1 PCM1 DNAH11	6.44e-05	1394	102	19	int:KCTD13
Interaction	HERC2P3 interactions	VIRMA HERC2P3	7.58e-05	3	102	2	int:HERC2P3
Interaction	PDZRN3 interactions	FAM13C SLFN11 STX11 PCM1	8.57e-05	46	102	4	int:PDZRN3
Interaction	PTPRO interactions	UGGT1 SH3GL1 UFL1 MAD2L1BP SLC3A2 YTHDF3	8.84e-05	143	102	6	int:PTPRO
Interaction	PTGS1 interactions	APC VIRMA PTGIS	9.72e-05	18	102	3	int:PTGS1
Interaction	DPYD interactions	LXN VIRMA TRNT1	9.72e-05	18	102	3	int:DPYD
Interaction	DPRX interactions	ZFHX4 ZNF644 ZFHX3	9.72e-05	18	102	3	int:DPRX
Interaction	NPIPB6 interactions	RANBP2 RGPD8 RGPD5	9.72e-05	18	102	3	int:NPIPB6
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RANBP2 RGPD8 ZC3H7B RGPD5	7.80e-04	115	65	4	769
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX3	1.30e-03	15	65	2	529
GeneFamily	Cadherin related	DCHS2 FAT4	1.67e-03	17	65	2	24
GeneFamily	CD molecules\|Mucins	MUC16 MUC5B	2.56e-03	21	65	2	648
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NFASC LRIG1 SIGLEC1 ALPK2	2.69e-03	161	65	4	593
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CASP8AP2 ORC3 RCN2 APC UFL1 ITGAV ITPR2 FAP ZNF644 N4BP2L2 NIPBL PCM1	9.47e-06	656	102	12	M18979
Coexpression	GSE11924_TH2_VS_TH17_CD4_TCELL_DN	RCN2 VIRMA FAP APPL2 LRIG1 NIPBL ALPK2	1.36e-05	200	102	7	M3165
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	APBA2 APC NFASC RYR2 MAPRE3 SEPTIN3 ZFHX4 ZFHX3 MLLT11 HERC1	1.39e-05	465	102	10	M39066
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FAT4 MUC5B RYR2 ZFHX4 SLC24A2 DNAH11	2.27e-07	184	102	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FAT4 MUC5B RYR2 ZFHX4 SLC24A2 DNAH11	2.27e-07	184	102	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FAT4 MUC5B RYR2 ZFHX4 SLC24A2 DNAH11	2.27e-07	184	102	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFASC RYR2 SEPTIN3 HFM1 STX11 DNASE1	1.19e-06	148	102	6	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BEST2 CFAP54 SLC24A4 RP1 ODAD3 DNAH11	1.50e-06	154	102	6	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BEST2 CFAP54 SLC24A4 RP1 ODAD3 DNAH11	1.50e-06	154	102	6	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FAT4 RYR2 NRP2 LRIG1 SLC24A2 ZFHX3	4.46e-06	186	102	6	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 DDR2 NFASC PTGIS NRP2 FAP	4.89e-06	189	102	6	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 DDR2 NFASC PTGIS NRP2 FAP	5.04e-06	190	102	6	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 DDR2 NFASC PTGIS NRP2 FAP	5.04e-06	190	102	6	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 DDR2 NFASC PTGIS NRP2 FAP	5.19e-06	191	102	6	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	RANBP2 DENND4A ZNF644 HERC1 PCM1 RGPD5	5.19e-06	191	102	6	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 DDR2 NFASC PTGIS NRP2 FAP	5.19e-06	191	102	6	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RCN2 NFASC PTGIS NRP2 ZFHX4 ENTPD1	5.35e-06	192	102	6	8ad6678df89175c5a4a835c8566f1552df3c996e
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DCHS2 PTGIS NRP2 FAP SNCAIP ZFHX4	5.35e-06	192	102	6	20ede290e01ad574afd122d72b59dbc52c595fad
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RCN2 NFASC PTGIS NRP2 ZFHX4 ENTPD1	5.35e-06	192	102	6	2f5378ea0b2fb2f672a36585d375f675983363a1
ToppCell	Fetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AMDHD2 NRP2 ITPR2 ENTPD1 SIGLEC1 STX11	5.51e-06	193	102	6	2d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B AK7 CFAP54 RP1 DNAH11	5.85e-06	195	102	6	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 NFASC PTGIS RYR2 NRP2 LRRC7	6.02e-06	196	102	6	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 NFASC PTGIS RYR2 NRP2 LRRC7	6.02e-06	196	102	6	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM13C NFASC RYR2 NRP2 SLC24A2 DNAH11	6.38e-06	198	102	6	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	AK7 FAM83B MAPRE3 CFAP54 RP1 ODAD3	6.57e-06	199	102	6	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AK7 CFAP54 RP1 ODAD3 DNAH11	2.89e-05	155	102	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AK7 CFAP54 RP1 ODAD3 DNAH11	2.89e-05	155	102	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_P4HA3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 FAT4 FAM83B SAG ZFHX3	3.08e-05	157	102	5	13f045df0cde2f7736b6ed3906beb06d694e2432
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGPD8 MUC16 NRP2 ALPK2 DNAH11	4.13e-05	167	102	5	8b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 FAT4 FAM83B RNF220 ZFHX3	4.37e-05	169	102	5	2abdd8ae9a5d88aac30992142d1b502c959bc015
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 DENND4A N4BP2L2 HERC1 PCM1	4.63e-05	171	102	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE2A AK7 NRP2 ZFHX3 ADPRHL1	4.89e-05	173	102	5	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	facs-Trachea-nan-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AK7 CFAP54 SLC24A4 RP1 ODAD3	4.89e-05	173	102	5	27ae126c720f20d1fe116abbcd358e4cff8baf6b
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	FAM13C NFASC PTGIS RYR2 RGPD5	4.89e-05	173	102	5	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AK7 CFAP54 SLC24A4 RP1 ODAD3	5.02e-05	174	102	5	f1510b0f7771936adf29ae3572feab55db31832b
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AK7 CFAP54 SLC24A4 RP1 ODAD3	5.02e-05	174	102	5	5d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B CFAP54 RP1 DNAH11	5.30e-05	176	102	5	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A ARHGAP23 APBA2 NRP2 SNCAIP	5.45e-05	177	102	5	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A ARHGAP23 APBA2 NRP2 SNCAIP	5.45e-05	177	102	5	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A ARHGAP23 APBA2 NRP2 SNCAIP	5.45e-05	177	102	5	c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AK7 CFAP54 RP1 ODAD3 DNAH11	5.60e-05	178	102	5	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	DCHS2 PDE2A NRP2 SNCAIP ZFHX4	5.60e-05	178	102	5	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM DCHS2 CYP27A1 MST1 ALPK2	6.38e-05	183	102	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XRN2 SH3KBP1 APC NIPBL PCM1	6.55e-05	184	102	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PTGIS RYR2 LRIG1 ZFHX3 LRRC7	6.72e-05	185	102	5	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 SYT2 NRP2 CFAP54 ALPK2	6.72e-05	185	102	5	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	AK7 CFAP54 RP1 ODAD3 DNAH11	6.72e-05	185	102	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AK7 CFAP54 RP1 ODAD3 DNAH11	6.72e-05	185	102	5	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	MUC16 AK7 CFAP54 RP1 DNAH11	6.72e-05	185	102	5	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 SYT2 NRP2 CFAP54 ALPK2	6.72e-05	185	102	5	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTGIS SNCAIP DHH ENTPD1 RP1	6.89e-05	186	102	5	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DDR2 LXN PTGIS MST1 ZFHX4	6.89e-05	186	102	5	7812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDE2A PTGIS SLC3A2 NRP2 DHH	6.89e-05	186	102	5	153c8b2fd8a6e2141ca97c626f82e5f081f3180a
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CASP8AP2 APC FAM83B ZNF644 LTN1	6.89e-05	186	102	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IDH2 FAM83B ITPR2 RP1 DNASE1	7.07e-05	187	102	5	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RANBP2 DENND4A ZNF644 HERC1 NIPBL	7.25e-05	188	102	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PDE2A ARHGAP23 NRP2 SNCAIP	7.25e-05	188	102	5	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 RP1 ADPRHL1 ALDH1B1 ALPK2	7.43e-05	189	102	5	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B ITGAV NRP2 RP1 ALPK2	7.43e-05	189	102	5	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 RP1 ADPRHL1 ALDH1B1 ALPK2	7.43e-05	189	102	5	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B ITGAV NRP2 RP1 ALPK2	7.43e-05	189	102	5	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTGIS SNCAIP DHH ENTPD1 RP1	7.62e-05	190	102	5	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 NFASC PTGIS NRP2 FAP	7.81e-05	191	102	5	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 AK7 CFAP54 RP1 DNAH11	7.81e-05	191	102	5	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 AK7 CFAP54 RP1 DNAH11	7.81e-05	191	102	5	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 PTGIS SNCAIP DHH ENTPD1	7.81e-05	191	102	5	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 AK7 CFAP54 RP1 DNAH11	7.81e-05	191	102	5	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-IPC_like-IPCs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FAM13C FAP MEX3A ZFHX4 MLLT11	8.00e-05	192	102	5	bd91bf0ceeac49dc5a18aa2e401244db0ca596ae
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	XRN2 ITPR2 TBCK NIPBL PCM1	8.00e-05	192	102	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 DENND4A N4BP2L2 HERC1 PCM1	8.00e-05	192	102	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-IPC_like\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FAM13C FAP MEX3A ZFHX4 MLLT11	8.00e-05	192	102	5	18fbf485ad762ba7a9ac3e19bad136b0cf3af3c5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IDH2 ITPR2 RP1 MST1L DNASE1	8.00e-05	192	102	5	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	MUC16 AK7 CFAP54 RP1 DNAH11	8.00e-05	192	102	5	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DCHS2 NRP2 FAP SNCAIP ZFHX4	8.20e-05	193	102	5	7cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAPRE3 CFAP54 LRIG1 RP1 DNAH11	8.20e-05	193	102	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFASC NRP2 FAP SNCAIP ZFHX4	8.20e-05	193	102	5	96c85b250d04b5f400512097d925061c6dc2906b
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	RCN2 ITPR2 MEX3A SNCAIP MLLT11	8.20e-05	193	102	5	2088f1d210c73f74685492c63065c62ac3f553e9
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	RCN2 ITPR2 MEX3A SNCAIP MLLT11	8.20e-05	193	102	5	f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	XRN2 ITPR2 TBCK NIPBL PCM1	8.20e-05	193	102	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A PTGIS SNCAIP SLC24A2 ENTPD1	8.40e-05	194	102	5	cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	DDR2 PTGIS FAP DHH ENTPD1	8.40e-05	194	102	5	2260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC PTGIS RYR2 ENTPD1 ZFHX3	8.40e-05	194	102	5	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC PTGIS RYR2 ENTPD1 ZFHX3	8.40e-05	194	102	5	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 AK7 CFAP54 RP1 DNAH11	8.40e-05	194	102	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 NFASC PTGIS FAP ZFHX3	8.40e-05	194	102	5	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 PTGIS SNCAIP DHH ENTPD1	8.40e-05	194	102	5	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	MUC16 AK7 CFAP54 RP1 DNAH11	8.40e-05	194	102	5	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	AK7 CFAP54 LRIG1 RP1 DNAH11	8.61e-05	195	102	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC PTGIS NRP2 FAP ZFHX4	8.61e-05	195	102	5	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	MUC5B AK7 CFAP54 RP1 DNAH11	8.61e-05	195	102	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC PTGIS NRP2 FAP ZFHX4	8.61e-05	195	102	5	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	AK7 CFAP54 LRIG1 RP1 DNAH11	8.61e-05	195	102	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	AK7 MAPRE3 CFAP54 RP1 DNAH11	8.61e-05	195	102	5	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	AK7 MAPRE3 CFAP54 RP1 DNAH11	8.61e-05	195	102	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	MUC16 AK7 CFAP54 RP1 DNAH11	8.82e-05	196	102	5	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 NFASC PTGIS NRP2 FAP	8.82e-05	196	102	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 NFASC PTGIS NRP2 FAP	8.82e-05	196	102	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	NFASC MEX3A EPC1 LRRC7 MLLT11	8.82e-05	196	102	5	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM13C NFASC RYR2 NRP2 ENTPD1	8.82e-05	196	102	5	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 ARHGAP23 NFASC SYT2 NRP2	8.82e-05	196	102	5	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AK7 MAPRE3 CFAP54 RP1 DNAH11	9.03e-05	197	102	5	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 AK7 RP1 PCM1 DNAH11	9.03e-05	197	102	5	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 AK7 RP1 PCM1 DNAH11	9.03e-05	197	102	5	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
Drug	Lobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; PC3; HT_HG-U133A	FAT4 DENND4A CYP27A1 APC HMOX2 RYR2 ENTPD1 ALDH1B1 ZC3H7B CDC25A	2.00e-08	199	101	10	5784_DN
Drug	estradiol, USP; Up 200; 0.1uM; PC3; HT_HG-U133A	AMDHD2 MUC5B RYR2 NRP2 ITPR2 ARHGEF9 ALDH1B1 CDC25A PCM1	2.48e-07	198	101	9	1208_UP
Drug	allulose 6-phosphate	MGAM AMDHD2 APC IDH2 PTGIS SIGLEC1 GCN1	7.96e-06	162	101	7	CID000000603
Drug	5-MSL	MGAM APC MAPRE3	1.36e-05	11	101	3	CID000165311
Drug	petroselenic acid	IDH2 LXN SIGLEC1	2.35e-05	13	101	3	CID000011634
Drug	Loracarbef [121961-22-6]; Down 200; 10.8uM; PC3; HT_HG-U133A	FAT4 APC IDH2 HMOX2 ALDH1B1 PCM1 EPHA1	2.73e-05	196	101	7	5073_DN
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; HL60; HG-U133A	MGAM DENND4A SH3GL1 RCN2 APC N4BP2L2 ZC3H7B	2.73e-05	196	101	7	1432_DN
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; PC3; HT_HG-U133A	UGGT1 APBA2 APC RYR2 ENTPD1 ZFHX3 ZC3H7B	2.82e-05	197	101	7	5803_DN
Drug	fluphenazine dihydrochloride; Up 200; 10uM; PC3; HT_HG-U133A	AMDHD2 APC MUC5B PTGIS RYR2 ENTPD1 PCM1	2.82e-05	197	101	7	1237_UP
Disease	atrial fibrillation	ITPR2 SLC24A4 ZFHX4 LRIG1 SLC24A2 ZFHX3 HERC1 PCM1	3.94e-05	371	100	8	EFO_0000275
Disease	obesity (implicated_via_orthology)	DCHS2 FAT4 ITPR2 ZFHX4 ZFHX3 ALDH1B1	9.41e-05	215	100	6	DOID:9970 (implicated_via_orthology)
Disease	Turcot syndrome (disorder)	APC MSH6	1.13e-04	5	100	2	C0265325
Disease	mastiha supplement exposure measurement, blood glutathione peroxidase measurement	SLC24A4 SLC24A2	1.13e-04	5	100	2	EFO_0600067, EFO_0600071
Disease	verbal memory measurement	SLC24A4 SLC24A2	2.36e-04	7	100	2	EFO_0009591
Disease	lung squamous cell carcinoma (is_marker_for)	DDR2 IDH2 FAP	2.49e-04	36	100	3	DOID:3907 (is_marker_for)
Disease	attempted suicide, mood disorder	SLC24A4 SLC24A2	3.14e-04	8	100	2	EFO_0004247, EFO_0004321
Disease	ovarian cancer (implicated_via_orthology)	APC MSH6	3.14e-04	8	100	2	DOID:2394 (implicated_via_orthology)
Disease	Lynch Syndrome	APC MSH6	4.03e-04	9	100	2	C4552100
Disease	autoimmune hepatitis (is_marker_for)	ZFHX3 DNASE1	6.13e-04	11	100	2	DOID:2048 (is_marker_for)
Disease	pro‐interleukin‐16 measurement	SLC24A4 SLC24A2	6.13e-04	11	100	2	EFO_0010629
Disease	Kartagener syndrome (implicated_via_orthology)	ODAD3 DNAH11	1.01e-03	14	100	2	DOID:0050144 (implicated_via_orthology)
Disease	anemia (implicated_via_orthology)	APC IREB2	1.16e-03	15	100	2	DOID:2355 (implicated_via_orthology)
Disease	word reading	SLC24A4 SLC24A2 ZFHX3	1.42e-03	65	100	3	EFO_0005300
Disease	breast carcinoma (is_marker_for)	MSH6 ZFHX3 CDC25A	1.48e-03	66	100	3	DOID:3459 (is_marker_for)
Disease	Cannabis use, age at onset	RYR2 LRRC7	1.87e-03	19	100	2	EFO_0004847, EFO_0007585
Disease	diastolic blood pressure, systolic blood pressure	FNDC3B FAM13C RYR2 MSH6 RNF220 LRIG1 ZFHX3 PCM1	2.02e-03	670	100	8	EFO_0006335, EFO_0006336
Disease	lung non-small cell carcinoma (is_marker_for)	DDR2 SLC3A2 FAP ZFHX3	2.66e-03	169	100	4	DOID:3908 (is_marker_for)
Disease	acute myeloid leukemia (is_implicated_in)	SH3GL1 IDH2 ITGAV	2.95e-03	84	100	3	DOID:9119 (is_implicated_in)
Disease	FEV/FEC ratio	FNDC3B MGAM DCHS2 IREB2 ITGAV FAM83B NRP2 TBCK EPC1 ZFHX3 HERC1	2.98e-03	1228	100	11	EFO_0004713
Disease	inflammatory bowel disease (implicated_via_orthology)	MST1 MST1L	3.24e-03	25	100	2	DOID:0050589 (implicated_via_orthology)
Disease	breast cancer (implicated_via_orthology)	APC MSH6	3.24e-03	25	100	2	DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AKDLNQYDFPSSDEE	EPC1	366	Q9H2F5
DLQAYEDPAQGALDF	EPHA1	601	P21709
QFLDPAQGYKDHDLD	BEST2	256	Q8NFU1
NLPNLEEIYSKDDGS	CFAP54	2236	Q96N23
DQEKNPEGDGLLEYS	MLLT11	56	Q13015
VGQPNEYDLNDSFLD	APLF	456	Q8IW19
DGNIPDNFREDLKYE	ALPK2	726	Q86TB3
DFLEIYNGASPDKGN	CDCP2	86	Q5VXM1
DNGKPFQESYALDLD	ALDH1B1	126	P30837
SDADDEDNYGARLKP	FAT4	4876	Q6V0I7
FSLSQLDKYAPENLD	ACAD9	581	Q9H845
LGFNAENPYTALDKA	DNAH11	1271	Q96DT5
NGINPEDLSQKEYSD	APBA2	531	Q99767
DPAKESYQDANLVFE	SAG	366	P10523
IYEDNGDDAPQNAKK	C1orf52	131	Q8N6N3
PLKNNDEGSLDIYAG	CASP8AP2	21	Q9UKL3
GFVRDLEKQYNNDDP	ARHGEF9	161	O43307
NGEDSALLELDPKYA	MUC5B	186	Q9HC84
DDTPFDGSNYLADKV	DENND4A	1101	Q7Z401
NPVNSELEAGNDFYD	SLC24A4	266	Q8NFF2
VNDYDKDNDGRLDPQ	RCN2	236	Q14257
QELEDYSEGGPLYKN	RANBP2	751	P49792
QELEDYSEGGPLYKN	RGPD5	751	Q99666
QELEDYSEGGPLYKN	RGPD8	751	O14715
KLFRNDQNSSGEPEY	IREB2	416	P48200
LKNYGENPEAYNEEL	PTPN23	31	Q9H3S7
AELNPDYRDAQNEGK	ITPR2	316	Q14571
PFNYGLSIEEKNEND	MSL3P1	36	P0C860
ELPQYDQDNLKSYGD	LTN1	1411	O94822
LDKDSLYLNGYNEPG	MUC16	14031	Q8WXI7
GNALSPKEFYELDLS	MAD2L1BP	156	Q15013
SYNKLSEIDPAGFED	LRIG1	76	Q96JA1
EPGKFLDQGLDDNYC	MST1L	196	Q2TV78
NLGNYGDKPSDNSDL	LRRC7	1236	Q96NW7
LDGNSNPYDIFLKDL	DDR2	141	Q16832
YKDQDPASFGADSLL	MGAM	691	O43451
QDPGALYDFNLDEEL	HERC1	2916	Q15751
LGDRFEGYDNPENLK	FAM83B	516	Q5T0W9
EGYDNPENLKANALY	FAM83B	521	Q5T0W9
LDDFYPAEEDTKQNS	PCM1	696	Q15154
SYRPKQENLEGADFL	MYF6	166	P23409
GLPSNNSLDFLDEEY	PDE2A	906	O00408
SKQGEEDYRPLFENF	NIPBL	1551	Q6KC79
SFEDDKDLQLPSGFN	NRP2	631	O60462
EFLKNAPNDASYDAV	GCN1	1301	Q92616
PFYAAEQDKGALEGS	HMOX2	266	P30519
ESPDNALQFRLYGKD	ENTPD1	231	P49961
LITPKAGFDSDYDQA	MSH6	926	P52701
FAKDPDEGNNAEVTY	DCHS2	1321	Q6V1P9
QFAFPSDKYEQDDLN	HFM1	91	A2PYH4
GSFDYSDEDNKPLQG	NFASC	1266	O94856
YFDLGLPNRDQTDDQ	IDH2	81	P48735
YNPDIIFKDEENSGA	DHH	81	O43323
GKLLDNLNQDAPDTY	DNASE1	71	P24855
DENDNLFHPKYTGED	FNDC3B	516	Q53EP0
EFDATGNRDYAKDDP	ITGAV	101	P06756
LKPAEAALYTDAFNE	CYP27A1	166	Q02318
DLLQIDPNFGSKEDF	SLC3A2	276	P08195
DPNFGSKEDFDSLLQ	SLC3A2	281	P08195
SENKAIFPDNYDAEE	ADPRHL1	241	Q8NDY3
NDGKYVLLNDQPDDD	APPL2	636	Q8NEU8
DANYDGKDYNPLLAR	MAPRE3	116	Q9UPY8
EPGKFLDQGLDDNYC	MST1	226	P26927
GLFGPKNDLEDYDAD	RYR2	1326	Q92736
DNDPRDLIGDFSKGY	CDC25A	331	P30304
IEDYFNKGKNEPEDS	ORC3	26	Q9UBD5
DLNILTDPEYKNGFN	RP1	1371	P56715
GKNPDEEDNTFYQRL	LXN	96	Q9BS40
EPENLGKLQFSLDYD	SYT2	136	Q8N9I0
PASLASLYEEDFKQD	CARS2	136	Q9HA77
YIGLPANASLEEFDK	TRNT1	266	Q96Q11
AQGDYPKDIFSLEER	SLC24A2	116	Q9UI40
YNRFLNPDGSEKKDF	PTGIS	406	Q16647
GRFAGKELDPQADNY	ODAD3	481	A5D8V7
AFSYLPQNDDELELK	SH3KBP1	106	Q96B97
NSDPADLIFQKDYLE	SLFN11	186	Q7Z7L1
GSAYEPENQSKDFLN	SNCAIP	246	Q9Y6H5
PEQLLSGKEDAANNY	TUBAL3	96	A6NHL2
SDADGKEYDFGTQLP	RNF220	156	Q5VTB9
DENNKENYPDAGALV	FAM13C	41	Q8NE31
SKGAQLEDYFPDSEN	HERC2P3	896	Q9BVR0
PDGNLSEEEKLFLSY	APOL5	91	Q9BWW9
DNDGELDTPINYSLK	APC	1016	P25054
PNGKFLAYAEFNDTD	FAP	216	Q12884
QKDAVNDDDFEPYLS	YTHDF3	26	Q7Z739
CKALYDFEPENDGEL	SH3GL1	311	Q99961
LQDFFDTNAYPKDDE	ZFHX4	2196	Q86UP3
QFPDAYGKELFDKAN	TMEM256	31	Q8N2U0
SENFDIEAPNYLSKE	PIGX	111	Q8TBF5
LEYNNENDFLAGSPD	MEX3A	296	A1L020
NGIEFYPQKEFDEDL	SEPTIN3	231	Q9UH03
LSKQYDQQFPDGDDE	STX11	11	O75558
PLFTDDKYNDFIEAN	ARHGAP23	991	Q9P227
IDFYPEDFAIDLNGK	XRN2	626	Q9H0D6
LLKDLQPEDSGSYNF	SIGLEC1	101	Q9BZZ2
GGEAFYPLLEDDQSN	TBCK	396	Q8TEA7
GLNFLNEYDETKPEL	ZNF644	1146	Q9H582
DGIADLERETFKYPN	VIRMA	306	Q69YN4
DLKELRDFNLDGAPY	UGGT1	1366	Q9NYU2
TGQGDYPLNNELDKE	UFL1	746	O94874
VLQDFFDANAYPKDD	ZFHX3	2256	Q15911
FDANAYPKDDEFEQL	ZFHX3	2261	Q15911
YPKDDEFEQLSNLLN	ZFHX3	2266	Q15911
PRDDDFGKYNFLLQE	ZC3H7B	941	Q9UGR2
DGFPKTYDQAKDLFN	AK7	481	Q96M32
FYEGHNNGLLKPDEE	N4BP2L2	206	Q92802
DAFQDLLATYGPLDN	AMDHD2	166	Q9Y303