Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	MYH3 MYH6 ABCA1 SMARCA5 ERCC6 HSP90AB4P MYH7B CHD9 ACSS2 KATNA1 MORC2 SLFN13 SLFN11	9.47e-06	614	98	13	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	MYH3 ABCA1 SMARCA5 ERCC6 HSP90AB4P CHD9 KATNA1 MORC2 SLFN13 SLFN11	6.17e-05	441	98	10	GO:0016887
GeneOntologyMolecularFunction	growth factor receptor binding	ANGPT1 ANGPT2 ERAP1 GRB2 FYN GRAP	2.11e-04	173	98	6	GO:0070851
GeneOntologyMolecularFunction	metalloaminopeptidase activity	TRHDE ERAP1 MMP17	2.75e-04	26	98	3	GO:0070006
GeneOntologyMolecularFunction	metallopeptidase activity	TRHDE ERAP1 MMP24 NLN MMP1 MMP17	4.59e-04	200	98	6	GO:0008237
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	SMARCA5 ERCC6 CHD9	7.89e-04	37	98	3	GO:0140658
GeneOntologyMolecularFunction	microfilament motor activity	MYH3 MYH6 MYH7B	8.54e-04	38	98	3	GO:0000146
GeneOntologyMolecularFunction	actin filament binding	MYH3 MYH6 MYH7B LIMD2 TRPV4 SCIN	8.91e-04	227	98	6	GO:0051015
Domain	Hemopexin-like_dom	VTN MMP24 MMP1 MMP17	5.61e-06	23	97	4	IPR000585
Domain	Hemopexin-like_repeat	VTN MMP24 MMP1 MMP17	5.61e-06	23	97	4	IPR018487
Domain	Hemopexin	VTN MMP24 MMP1 MMP17	5.61e-06	23	97	4	PF00045
Domain	HEMOPEXIN	VTN MMP24 MMP1 MMP17	5.61e-06	23	97	4	PS00024
Domain	-	VTN MMP24 MMP1 MMP17	5.61e-06	23	97	4	2.110.10.10
Domain	HEMOPEXIN_2	VTN MMP24 MMP1 MMP17	5.61e-06	23	97	4	PS51642
Domain	HX	VTN MMP24 MMP1 MMP17	5.61e-06	23	97	4	SM00120
Domain	ZINC_PROTEASE	TRHDE ERAP1 MMP24 NLN MMP1 MMP17	1.20e-05	98	97	6	PS00142
Domain	Myosin_N	MYH3 MYH6 MYH7B	5.91e-05	15	97	3	PF02736
Domain	Myosin_N	MYH3 MYH6 MYH7B	5.91e-05	15	97	3	IPR004009
Domain	DUF2075	SLFN13 SLFN11	7.98e-05	3	97	2	IPR018647
Domain	DUF2075	SLFN13 SLFN11	7.98e-05	3	97	2	PF09848
Domain	Hemopexin_CS	VTN MMP24 MMP1	8.76e-05	17	97	3	IPR018486
Domain	Myosin_tail_1	MYH3 MYH6 MYH7B	1.05e-04	18	97	3	PF01576
Domain	Myosin_tail	MYH3 MYH6 MYH7B	1.05e-04	18	97	3	IPR002928
Domain	Pept_M10A_stromelysin-type	MMP24 MMP1 MMP17	1.05e-04	18	97	3	IPR016293
Domain	Fibrinogen_CS	ANGPT1 ANGPT2 FGB	1.24e-04	19	97	3	IPR020837
Domain	Myosin-like_IQ_dom	MYH3 MYH6 MYH7B	1.24e-04	19	97	3	IPR027401
Domain	-	MYH3 MYH6 MYH7B	1.24e-04	19	97	3	4.10.270.10
Domain	PG_binding_1	MMP24 MMP1 MMP17	1.45e-04	20	97	3	PF01471
Domain	Peptidoglycan-bd-like	MMP24 MMP1 MMP17	1.45e-04	20	97	3	IPR002477
Domain	SH2	GRB2 PTK6 FGR FYN GRAP	1.82e-04	101	97	5	PF00017
Domain	M10A_MMP	MMP24 MMP1 MMP17	2.23e-04	23	97	3	IPR033739
Domain	Pept_M10A	MMP24 MMP1 MMP17	2.23e-04	23	97	3	IPR021190
Domain	Fibrinogen_a/b/g_C_2	ANGPT1 ANGPT2 FGB	2.54e-04	24	97	3	IPR014715
Domain	Peptidase_M10	MMP24 MMP1 MMP17	2.54e-04	24	97	3	PF00413
Domain	-	ANGPT1 ANGPT2 FGB	2.54e-04	24	97	3	4.10.530.10
Domain	SH2	GRB2 PTK6 FGR FYN GRAP	2.71e-04	110	97	5	SM00252
Domain	SH2	GRB2 PTK6 FGR FYN GRAP	2.83e-04	111	97	5	PS50001
Domain	SH2	GRB2 PTK6 FGR FYN GRAP	2.95e-04	112	97	5	IPR000980
Domain	-	GRB2 PTK6 FGR FYN GRAP	2.95e-04	112	97	5	3.30.505.10
Domain	Fibrinogen_C	ANGPT1 ANGPT2 FGB	3.63e-04	27	97	3	PF00147
Domain	-	ERN2 EIF2AK3	3.95e-04	6	97	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	ERN2 EIF2AK3	3.95e-04	6	97	2	IPR027295
Domain	ZnMc	MMP24 MMP1 MMP17	4.50e-04	29	97	3	SM00235
Domain	Peptidase_Metallo	MMP24 MMP1 MMP17	4.50e-04	29	97	3	IPR006026
Domain	FBG	ANGPT1 ANGPT2 FGB	4.50e-04	29	97	3	SM00186
Domain	-	ANGPT1 ANGPT2 FGB	4.98e-04	30	97	3	3.90.215.10
Domain	Fibrinogen_a/b/g_C_1	ANGPT1 ANGPT2 FGB	4.98e-04	30	97	3	IPR014716
Domain	AlbA_2	SLFN13 SLFN11	5.51e-04	7	97	2	PF04326
Domain	Schlafen	SLFN13 SLFN11	5.51e-04	7	97	2	IPR029684
Domain	Schlafen_AAA_dom	SLFN13 SLFN11	5.51e-04	7	97	2	IPR007421
Domain	Pkinase_Tyr	PTK6 AATK GUCY2D FGR FYN	5.64e-04	129	97	5	PF07714
Domain	SNF2_N	SMARCA5 ERCC6 CHD9	6.04e-04	32	97	3	IPR000330
Domain	FIBRINOGEN_C_1	ANGPT1 ANGPT2 FGB	6.04e-04	32	97	3	PS00514
Domain	SNF2_N	SMARCA5 ERCC6 CHD9	6.04e-04	32	97	3	PF00176
Domain	Fibrinogen_a/b/g_C_dom	ANGPT1 ANGPT2 FGB	6.04e-04	32	97	3	IPR002181
Domain	FIBRINOGEN_C_2	ANGPT1 ANGPT2 FGB	6.04e-04	32	97	3	PS51406
Domain	MFS_1	SLC17A4 SLC18B1 SLC17A8 SVOP	6.92e-04	77	97	4	PF07690
Domain	MFS	SLC17A4 SLC18B1 SLC17A8 SVOP	6.92e-04	77	97	4	IPR011701
Domain	ERAP1-like_C_dom	TRHDE ERAP1	7.32e-04	8	97	2	IPR024571
Domain	ERAP1_C	TRHDE ERAP1	7.32e-04	8	97	2	PF11838
Domain	Ser-Thr/Tyr_kinase_cat_dom	PTK6 AATK GUCY2D FGR FYN	7.66e-04	138	97	5	IPR001245
Domain	MetalloPept_cat_dom	MMP24 NLN MMP1 MMP17	8.38e-04	81	97	4	IPR024079
Domain	-	MMP24 NLN MMP1 MMP17	8.38e-04	81	97	4	3.40.390.10
Domain	SH3	GRB2 PTK6 FGR MCF2L FYN GRAP	9.20e-04	216	97	6	SM00326
Domain	SH3	GRB2 PTK6 FGR MCF2L FYN GRAP	9.20e-04	216	97	6	PS50002
Domain	Myosin_head_motor_dom	MYH3 MYH6 MYH7B	1.00e-03	38	97	3	IPR001609
Domain	MYOSIN_MOTOR	MYH3 MYH6 MYH7B	1.00e-03	38	97	3	PS51456
Domain	Myosin_head	MYH3 MYH6 MYH7B	1.00e-03	38	97	3	PF00063
Domain	MYSc	MYH3 MYH6 MYH7B	1.00e-03	38	97	3	SM00242
Domain	SH3_domain	GRB2 PTK6 FGR MCF2L FYN GRAP	1.01e-03	220	97	6	IPR001452
Domain	CYSTEINE_SWITCH	MMP24 MMP1 MMP17	1.25e-03	41	97	3	PS00546
Domain	Pept_M10_metallopeptidase	MMP24 MMP1 MMP17	1.44e-03	43	97	3	IPR001818
Domain	P-loop_NTPase	MYH3 MYH6 ABCA1 SMARCA5 ERCC6 MYH7B CHD9 KATNA1 EFTUD2 SLFN13 SULT6B1 SLFN11	1.46e-03	848	97	12	IPR027417
Domain	PROTEIN_KINASE_TYR	PTK6 AATK FGR FYN	1.64e-03	97	97	4	PS00109
Domain	Tyr_kinase_AS	PTK6 AATK FGR FYN	1.64e-03	97	97	4	IPR008266
Domain	SH3_1	GRB2 PTK6 FGR FYN GRAP	1.65e-03	164	97	5	PF00018
Domain	Peptidase_M1	TRHDE ERAP1	1.70e-03	12	97	2	IPR001930
Domain	CRAL_TRIO_2	MCF2 MCF2L	1.70e-03	12	97	2	PF13716
Domain	MATH/TRAF_dom	SPOPL SPOP	1.70e-03	12	97	2	IPR002083
Domain	MATH	SPOPL SPOP	1.70e-03	12	97	2	PS50144
Domain	MATH	SPOPL SPOP	1.70e-03	12	97	2	SM00061
Domain	MATH	SPOPL SPOP	1.70e-03	12	97	2	PF00917
Domain	Peptidase_M1	TRHDE ERAP1	2.01e-03	13	97	2	PF01433
Domain	Peptidase_M1_N	TRHDE ERAP1	2.01e-03	13	97	2	IPR014782
Domain	MORN	RSPH10B JPH3	2.33e-03	14	97	2	SM00698
Domain	-	SPOPL SPOP	2.33e-03	14	97	2	2.60.210.10
Domain	MFS	SLC17A4 SLC18B1 SLC17A8 SVOP	2.43e-03	108	97	4	PS50850
Domain	MORN	RSPH10B JPH3	2.68e-03	15	97	2	IPR003409
Domain	MORN	RSPH10B JPH3	2.68e-03	15	97	2	PF02493
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP24 SPOCK3 MMP1 MMP17	3.14e-05	33	78	4	M26976
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP24 SPOCK3 MMP1 MMP17	5.55e-05	38	78	4	MM14611
Pathway	REACTOME_TIE2_SIGNALING	ANGPT1 ANGPT2 GRB2	1.05e-04	17	78	3	MM14836
Pathway	REACTOME_TIE2_SIGNALING	ANGPT1 ANGPT2 GRB2	1.25e-04	18	78	3	M11932
Pathway	PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	ANGPT1 ANGPT2 GRB2 FYN	1.52e-04	49	78	4	M92
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	SEL1L DNAJC13 EOGT CHERP HSP90AB4P ERAP1 THUMPD3 CIR1 GRB2 APEH OAT CAT METTL13 EHMT1 PDCD11 FYN CNOT3	1.45e-07	1297	99	17	33545068
Pubmed	Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases.	GRB2 FGR FYN	7.77e-07	7	99	3	8805332
Pubmed	The GTPase dynamin binds to and is activated by a subset of SH3 domains.	GRB2 FGR FYN	1.24e-06	8	99	3	8402898
Pubmed	The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling.	GRB2 FYN GRAP	1.86e-06	9	99	3	8995379
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CERK SMARCA5 ERCC6 GRB2 CHD9 POGZ CALML6 METTL13 SLC25A13 EHMT1 FGB SPOP ABHD8 SLFN11	3.40e-06	1116	99	14	31753913
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ANGPT1 ERAP1 NLN METTL13 AATK EHMT1 HPS5	3.88e-06	225	99	7	12168954
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	GRB2 CALML6 PTK6 MMP24 EHMT1 PLA2G4F MMP1 FGR MMP17 FYN GRAP	7.64e-06	730	99	11	34857952
Pubmed	Admission angiopoietin levels in children with septic shock.	ANGPT1 ANGPT2	8.02e-06	2	99	2	18092380
Pubmed	Dynamic changes in serum angiopoietin-1, angiopoietin-2, and angiopoietin-2/angiopoietin-1 ratio in acute myocardial infarction patients treated with primary percutaneous coronary intervention.	ANGPT1 ANGPT2	8.02e-06	2	99	2	22642477
Pubmed	Sonic hedgehog inversely regulates the expression of angiopoietin-1 and angiopoietin-2 in fibroblasts.	ANGPT1 ANGPT2	8.02e-06	2	99	2	17273793
Pubmed	Preliminary observations on ANGPT1 and ANGPT2 polymorphisms in systemic sclerosis: ANGPT2 rs2442598 and rs3739390 are associated with disease susceptibility and diffuse disease subtype.	ANGPT1 ANGPT2	8.02e-06	2	99	2	34643357
Pubmed	Catalase binds Grb2 in tumor cells when stimulated with serum or ligands for integrin receptors.	GRB2 CAT	8.02e-06	2	99	2	15182856
Pubmed	Endothelial function in patients with metabolic syndrome and erectile dysfunction: a question of angiopoietin imbalance?	ANGPT1 ANGPT2	8.02e-06	2	99	2	23785018
Pubmed	Angiopoietin-2 levels as a biomarker of cardiovascular risk in patients with hypertension.	ANGPT1 ANGPT2	8.02e-06	2	99	2	18382887
Pubmed	Angiopoietin-1 and -2 exert antagonistic functions in tumor angiogenesis, yet both induce lymphangiogenesis.	ANGPT1 ANGPT2	8.02e-06	2	99	2	21778249
Pubmed	Angiogenic axis angiopoietin-1 and angiopoietin-2/Tie-2 in non-small cell lung cancer: a bronchoalveolar lavage and serum study.	ANGPT1 ANGPT2	8.02e-06	2	99	2	23835996
Pubmed	Angiopoietin-1 protects myocardial endothelial cell function blunted by angiopoietin-2 and high glucose condition.	ANGPT1 ANGPT2	8.02e-06	2	99	2	21113176
Pubmed	Angiopoietin-1 and angiopoietin-2 as serum biomarkers for ectopic pregnancy and missed abortion: a case-control study.	ANGPT1 ANGPT2	8.02e-06	2	99	2	23099117
Pubmed	Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy.	ANGPT1 ANGPT2	8.02e-06	2	99	2	15047628
Pubmed	The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors.	ANGPT1 ANGPT2	8.02e-06	2	99	2	15213103
Pubmed	Changes in circulating levels and ratios of angiopoietins during pregnancy but not during the menstrual cycle and controlled ovarian stimulation.	ANGPT1 ANGPT2	8.02e-06	2	99	2	19476937
Pubmed	Pro-Angiogenic Actions of CMC-Derived Extracellular Vesicles Rely on Selective Packaging of Angiopoietin 1 and 2, but Not FGF-2 and VEGF.	ANGPT1 ANGPT2	8.02e-06	2	99	2	31102187
Pubmed	Selective functions of angiopoietins and vascular endothelial growth factor on blood vessels: the concept of "vascular domain".	ANGPT1 ANGPT2	8.02e-06	2	99	2	12858538
Pubmed	Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma.	ANGPT1 ANGPT2	8.02e-06	2	99	2	15094228
Pubmed	Effect of HIV-1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction.	ANGPT1 ANGPT2	8.02e-06	2	99	2	34726064
Pubmed	Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock.	ANGPT1 ANGPT2	8.02e-06	2	99	2	30745813
Pubmed	Imbalance of angiopoietin-1 and angiopoetin-2 in severe dengue and relationship with thrombocytopenia, endothelial activation, and vascular stability.	ANGPT1 ANGPT2	8.02e-06	2	99	2	22949515
Pubmed	Levels of angiopoietins 1 and 2 in induced sputum supernatant in patients with COPD.	ANGPT1 ANGPT2	8.02e-06	2	99	2	22483377
Pubmed	A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia.	ANGPT1 ANGPT2	8.02e-06	2	99	2	23915833
Pubmed	Differential regulation of angiopoietin 1 and angiopoietin 2 during dengue virus infection of human umbilical vein endothelial cells: implications for endothelial hyperpermeability.	ANGPT1 ANGPT2	8.02e-06	2	99	2	23989887
Pubmed	Intrahepatic angiopoietin-2 correlates with chronic hepatitis C progression and is induced in hepatitis C virus replicon systems.	ANGPT1 ANGPT2	8.02e-06	2	99	2	28027429
Pubmed	Arterial stiffness in hypertensives in relation to expression of angiopoietin-1 and 2 genes in peripheral monocytes.	ANGPT1 ANGPT2	8.02e-06	2	99	2	20072144
Pubmed	Regulation of angiopoietin expression by bacterial lipopolysaccharide.	ANGPT1 ANGPT2	8.02e-06	2	99	2	18310225
Pubmed	Increased levels of angiopoietins 1 and 2 in sputum supernatant in severe refractory asthma.	ANGPT1 ANGPT2	8.02e-06	2	99	2	22229541
Pubmed	Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease.	ANGPT1 ANGPT2	8.02e-06	2	99	2	27991547
Pubmed	Reduced Ang2 expression in aging endothelial cells.	ANGPT1 ANGPT2	8.02e-06	2	99	2	27137842
Pubmed	Angiopoietins as serum biomarkers for lymphatic anomalies.	ANGPT1 ANGPT2	8.02e-06	2	99	2	27990590
Pubmed	Evaluation of angiopoietin 1 and 2, vascular endothelial growth factor, and tumor necrosis factor alpha levels in asthmatic children.	ANGPT1 ANGPT2	8.02e-06	2	99	2	25584916
Pubmed	Ratio of angiopoietin-2 to angiopoietin-1 predicts mortality in acute lung injury induced by paraquat.	ANGPT1 ANGPT2	8.02e-06	2	99	2	23302768
Pubmed	Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23.	ANGPT1 ANGPT2	8.02e-06	2	99	2	9545648
Pubmed	Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.	ANGPT1 ANGPT2	8.02e-06	2	99	2	19815705
Pubmed	Angiopoietin-1/angiopoietin-2 ratio for prediction of preeclampsia.	ANGPT1 ANGPT2	8.02e-06	2	99	2	19478794
Pubmed	Angiogenic response to major lung resection for non-small cell lung cancer with video-assisted thoracic surgical and open access.	ANGPT1 ANGPT2	8.02e-06	2	99	2	23024612
Pubmed	Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy.	ANGPT1 ANGPT2	8.02e-06	2	99	2	36662891
Pubmed	Vitreous levels of angiopoietin-1 and angiopoietin-2 in eyes with retinopathy of prematurity.	ANGPT1 ANGPT2	8.02e-06	2	99	2	21168819
Pubmed	Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma.	ANGPT1 ANGPT2	8.02e-06	2	99	2	12717391
Pubmed	Association of Angiopoietin Dysregulation in Placental Malaria with Adverse Birth Outcomes.	ANGPT1 ANGPT2	8.02e-06	2	99	2	32399088
Pubmed	SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis.	SEL1L EIF2AK3	8.02e-06	2	99	2	37644166
Pubmed	The C-terminal 26-residue peptide of serpin A1 stimulates proliferation of breast and liver cancer cells: role of protein kinase C and CD47.	SERPINA1 CD47	8.02e-06	2	99	2	15498560
Pubmed	A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.	SPOPL SPOP	8.02e-06	2	99	2	16740475
Pubmed	Deregulation of levels of angiopoietin-1 and angiopoietin-2 is associated with severe courses of hantavirus infection.	ANGPT1 ANGPT2	8.02e-06	2	99	2	28734140
Pubmed	A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia.	ANGPT1 ANGPT2	8.02e-06	2	99	2	12612904
Pubmed	Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression.	ANGPT1 ANGPT2	8.02e-06	2	99	2	26044849
Pubmed	Dysregulation of angiopoietins is associated with placental malaria and low birth weight.	ANGPT1 ANGPT2	8.02e-06	2	99	2	20208992
Pubmed	Angiopoietin-1 is an apoptosis survival factor for endothelial cells.	ANGPT1 ANGPT2	8.02e-06	2	99	2	10218485
Pubmed	Angiopoietin-1 and -2 as markers for disease severity in hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli.	ANGPT1 ANGPT2	8.02e-06	2	99	2	26945868
Pubmed	Gingipains from the Periodontal Pathogen Porphyromonas gingivalis Play a Significant Role in Regulation of Angiopoietin 1 and Angiopoietin 2 in Human Aortic Smooth Muscle Cells.	ANGPT1 ANGPT2	8.02e-06	2	99	2	26283334
Pubmed	Evolutionary expansion of SPOP and associated TD/POZ gene family: impact of evolutionary route on gene expression pattern.	SPOPL SPOP	8.02e-06	2	99	2	20399258
Pubmed	Angiopoietin 1 and angiopoietin 2 are associated with medial thickening of hepatic arterial branches in biliary atresia.	ANGPT1 ANGPT2	8.02e-06	2	99	2	24126820
Pubmed	Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: relationship to VEGF, glycaemic control, endothelial damage/dysfunction and atherosclerosis.	ANGPT1 ANGPT2	8.02e-06	2	99	2	15823283
Pubmed	Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation.	ANGPT1 ANGPT2	8.02e-06	2	99	2	16836957
Pubmed	The ratio of plasma angiopoietin-2 to angiopoietin-1 as a prognostic biomarker in patients with sepsis.	ANGPT1 ANGPT2	8.02e-06	2	99	2	32059166
Pubmed	Angiopoietin 1 and angiopoietin 2 in follicular fluid of women undergoing a long protocol.	ANGPT1 ANGPT2	8.02e-06	2	99	2	22000910
Pubmed	Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts.	MMP24 MMP17	8.02e-06	2	99	2	10471807
Pubmed	Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children.	ANGPT1 ANGPT2	8.02e-06	2	99	2	19300530
Pubmed	Angiopoietin-2/angiopoietin-1 as non-invasive biomarker of cirrhosis in chronic hepatitis C.	ANGPT1 ANGPT2	8.02e-06	2	99	2	27956798
Pubmed	Endometrial angiopoietin expression and modulation by thrombin and steroid hormones: a mechanism for abnormal angiogenesis following long-term progestin-only contraception.	ANGPT1 ANGPT2	8.02e-06	2	99	2	15161644
Pubmed	A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiretroviral therapy.	ANGPT1 ANGPT2	8.02e-06	2	99	2	23734875
Pubmed	The angiopoietin 1/angiopoietin 2 balance as a prognostic marker in primary glioblastoma multiforme.	ANGPT1 ANGPT2	8.02e-06	2	99	2	18991494
Pubmed	Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.	ANGPT1 ANGPT2	8.02e-06	2	99	2	12361603
Pubmed	Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.	ANGPT1 ANGPT2	8.02e-06	2	99	2	29323190
Pubmed	Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays.	ANGPT1 ANGPT2	8.02e-06	2	99	2	18664247
Pubmed	Disruption of vascular endothelial homeostasis in systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: The dynamic roles of angiopoietin-1 and -2.	ANGPT1 ANGPT2	8.02e-06	2	99	2	26908294
Pubmed	Angiopoietins in haematopoietic stem cell mobilisation in patients with haematological malignancies.	ANGPT1 ANGPT2	8.02e-06	2	99	2	25369606
Pubmed	Contactin-1 Is Reduced in Cerebrospinal Fluid of Parkinson's Disease Patients and Is Present within Lewy Bodies.	CNTN2 CNTN1	8.02e-06	2	99	2	32806791
Pubmed	[Expression of angiopoietin-1 and 2 in squamous cell carcinoma of the head and neck areas and normal mucosa].	ANGPT1 ANGPT2	8.02e-06	2	99	2	16229183
Pubmed	Diagnostic and prognostic significance of serum angiopoietin-1 and -2 concentrations in patients with pulmonary hypertension.	ANGPT1 ANGPT2	8.02e-06	2	99	2	34326408
Pubmed	Common protective and diverse smooth muscle cell effects of AAV-mediated angiopoietin-1 and -2 expression in rat cardiac allograft vasculopathy.	ANGPT1 ANGPT2	8.02e-06	2	99	2	16690881
Pubmed	Opposing effects of the angiopoietins on the thrombin-induced permeability of human pulmonary microvascular endothelial cells.	ANGPT1 ANGPT2	8.02e-06	2	99	2	21858121
Pubmed	Endovascular cooling and endothelial activation in hemorrhagic stroke patients.	ANGPT1 ANGPT2	8.02e-06	2	99	2	21380565
Pubmed	Dynamic contrast-enhanced magnetic resonance imaging parameters correlate with advanced revised-ISS and angiopoietin-1/angiopoietin-2 ratio in patients with multiple myeloma.	ANGPT1 ANGPT2	8.02e-06	2	99	2	28766001
Pubmed	Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.	SLFN13 SLFN11	8.02e-06	2	99	2	37833372
Pubmed	Angiopoietin balance in septic shock patients with acute lung injury: effect of direct hemoperfusion with polymyxin B-immobilized fiber.	ANGPT1 ANGPT2	8.02e-06	2	99	2	21884468
Pubmed	Angiopoietin balance in septic shock patients treated by direct hemoperfusion with polymyxin b-immobilized fiber.	ANGPT1 ANGPT2	8.02e-06	2	99	2	19954476
Pubmed	Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses.	ANGPT1 ANGPT2	8.02e-06	2	99	2	22357955
Pubmed	[Significance of a reversal expression of the angiopoietin-1 and 2 in oral squamous cell carcinoma].	ANGPT1 ANGPT2	8.02e-06	2	99	2	19567053
Pubmed	Expression of angiopoietin-2 is correlated with vascularization and tumor size in human colorectal adenocarcinoma.	ANGPT1 ANGPT2	8.02e-06	2	99	2	17785951
Pubmed	Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses.	ANGPT1 ANGPT2	8.02e-06	2	99	2	15498854
Pubmed	Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2.	ANGPT1 ANGPT2	8.02e-06	2	99	2	17341311
Pubmed	Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia.	ANGPT1 ANGPT2	8.02e-06	2	99	2	25275496
Pubmed	Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.	SPOPL SPOP	8.02e-06	2	99	2	16651542
Pubmed	Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity.	ANGPT1 ANGPT2	8.02e-06	2	99	2	10514510
Pubmed	Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.	SLFN13 SLFN11	8.02e-06	2	99	2	29563550
Pubmed	Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor.	GRB2 FYN GRAP	9.93e-06	15	99	3	11741599
Pubmed	Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10).	GRB2 FYN GRAP	9.93e-06	15	99	3	25036101
Pubmed	Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2.	ANGPT1 ANGPT2	2.40e-05	3	99	2	15769741
Pubmed	Autocrine/paracrine role of the angiopoietin-1 and -2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis.	ANGPT1 ANGPT2	2.40e-05	3	99	2	14991531
Pubmed	Angiopoietin-1 but not angiopoietin-2 induces IL-8 synthesis and release by human neutrophils.	ANGPT1 ANGPT2	2.40e-05	3	99	2	22015631
Pubmed	Placental mRNA expression of angiopoietins (Ang)-1, Ang-2 and their receptor Tie-2 is altered in pregnancies complicated by preeclampsia.	ANGPT1 ANGPT2	2.40e-05	3	99	2	25047691
Pubmed	Plasma concentrations of Ang-1, Ang-2 and Tie-2 in gastric cancer.	ANGPT1 ANGPT2	2.40e-05	3	99	2	22449617
Interaction	NUTM2F interactions	GRB2 APEH CAT IRF6 SLFN11	2.70e-06	45	99	5	int:NUTM2F
Interaction	MMP17 interactions	MMP24 MMP1 MMP17	1.35e-05	10	99	3	int:MMP17
Interaction	TEK interactions	SMARCA5 ANGPT1 ANGPT2 GRB2 POGZ SLFN11	2.67e-05	119	99	6	int:TEK
Interaction	HASPIN interactions	VTN CTR9 EHMT1 SCIN FYN CNTN1	3.22e-05	123	99	6	int:HASPIN
Cytoband	10q23.33	EXOC6 FRA10AC1	1.13e-03	23	99	2	10q23.33
Cytoband	17p13.1	MYH3 RCVRN GUCY2D	2.17e-03	118	99	3	17p13.1
Cytoband	20q11.22	MYH7B ACSS2	2.92e-03	37	99	2	20q11.22
Cytoband	Ensembl 112 genes in cytogenetic band chr9q31	ABCA1 NIPSNAP3B ALDOB	3.31e-03	137	99	3	chr9q31
Cytoband	9q31.1	ABCA1 NIPSNAP3B	3.57e-03	41	99	2	9q31.1
Cytoband	7p22.1	RSPH10B2 RSPH10B	4.67e-03	47	99	2	7p22.1
GeneFamily	Myosin heavy chains	MYH3 MYH6 MYH7B	2.45e-05	15	70	3	1098
GeneFamily	SH2 domain containing	GRB2 PTK6 FGR FYN GRAP	4.47e-05	101	70	5	741
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP24 MMP1 MMP17	1.06e-04	24	70	3	891
GeneFamily	Fibrinogen C domain containing	ANGPT1 ANGPT2 FGB	1.20e-04	25	70	3	554
GeneFamily	Schlafen family	SLFN13 SLFN11	3.06e-04	7	70	2	1110
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HOMTN	TRHDE SRRM4 MCF2 MMP24 NLN AATK SPOCK3 MCF2L SVOP CNTN2 JPH3	2.62e-07	389	99	11	M39073
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	TRHDE CHERP SRRM4 MCF2 MMP24 NLN AATK SPOCK3 NTM MCF2L MMP17 SVOP JPH3	2.48e-06	703	99	13	M39070
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HSERT	SRRM4 MCF2 MMP24 AATK SPOCK3 CD47 MCF2L SVOP CNTN1 JPH3	8.03e-06	450	99	10	M39072
Coexpression	AIZARANI_LIVER_C11_HEPATOCYTES_1	ABCA1 VTN SELENBP1 OAT CAT SERPINA1 FGB ALDOB	1.78e-05	298	99	8	M39115
Coexpression	AIZARANI_LIVER_C17_HEPATOCYTES_3	ABCA1 VTN SELENBP1 SERPINA1 FGB	4.33e-05	102	99	5	M39119
Coexpression	BROWNE_HCMV_INFECTION_4HR_DN	ERCC6 GCNT1 MORC2 PHKA1 SERPINA1 SPOP GRAP	4.90e-05	252	99	7	M789
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VTN OAT IRF6 GCNT1 SCGN SERPINA1 SLFN13 FGB	1.43e-08	197	99	8	6ee6939c492bedf1f96a715da7a26a4c55a7c36f
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ST6GALNAC1 OAT IRF6 CROT SERPINB13 SPOCK3 MMP1	3.04e-07	198	99	7	7063d74d79f53d5c59c853a2575f9d3ef12f19ea
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ACSS2 ERN2 PLA2G4F SCIN	4.64e-06	193	99	6	402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ACSS2 ERN2 PLA2G4F SCIN	4.64e-06	193	99	6	7ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCell	background-NK_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	SERPINA1 SYTL3 SLFN13 FGB ALDOB FYN	5.22e-06	197	99	6	e8e1d3e557fe821efe81012e759e35e4ae33ce86
ToppCell	distal-3-Epithelial-Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ST6GALNAC1 OAT IRF6 SPOCK3 TRPV4 MMP1	5.22e-06	197	99	6	72ac9068cfd8f04c521a858d55eb8b5764de0282
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	ST6GALNAC1 IRF6 CROT SERPINB13 SPOCK3 MMP1	5.22e-06	197	99	6	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	Biopsy_IPF-Epithelial-Basal\|Biopsy_IPF / Sample group, Lineage and Cell type	OAT IRF6 CROT SERPINB13 SPOCK3 MMP1	5.69e-06	200	99	6	5cea84581201cee7ba8141b96e65864f4fd67113
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ST6GALNAC1 IRF6 CROT SERPINB13 SPOCK3 MMP1	5.69e-06	200	99	6	592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ST6GALNAC1 IRF6 CROT SERPINB13 SPOCK3 MMP1	5.69e-06	200	99	6	8cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 OAT GCNT1 SERPINA1 FGB ALDOB	5.69e-06	200	99	6	0ca955b71b97571b45e9e89004f1d0bb9fc9e67b
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ST6GALNAC1 IRF6 CROT SERPINB13 SPOCK3 MMP1	5.69e-06	200	99	6	61811380d9252f12f27b7ad4752380b52692677f
ToppCell	droplet-Liver-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN CAT CROT FGB ALDOB	1.88e-05	146	99	5	d9df42f8e44018b149a84f07c540cdba74d6374a
ToppCell	droplet-Liver-hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN CAT CROT FGB ALDOB	1.88e-05	146	99	5	a9fa64617c7fb7a66de77360c5642c1da91e465c
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN CAT CROT FGB ALDOB	1.88e-05	146	99	5	e03658ead410d003e2b18fe94da086a38560b8e7
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN CAT CROT FGB ALDOB	1.88e-05	146	99	5	9d7122cc640500c7cd93230df06e331c31625bd5
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LIMD2 SYTL3 SLFN13 FGR FYN	2.35e-05	153	99	5	d8773ee16c7d3e0834b9f64054d42336d6f9833b
ToppCell	droplet-Liver-nan-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN CAT CROT FGB ALDOB	2.67e-05	157	99	5	b72c6a1ed17bfc32d9dec193d934ea82e80b6bd5
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 SLC17A4 IRF6 SERPINA1 FGB	2.75e-05	158	99	5	ab707bfe782c667b252b488ad1d7efd49cf0a899
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN SELENBP1 CAT FGB ALDOB	3.19e-05	163	99	5	61b4e38d7bbbb031100670928e6fd4f7ea23814f
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN SELENBP1 CAT FGB ALDOB	3.19e-05	163	99	5	0b4d234bdd57d5e991f68942333ca89f70ea28df
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN SELENBP1 CAT FGB ALDOB	3.19e-05	163	99	5	cc728796e52d0e6cc1198e0732370c62380e951d
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-CD45____T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 PLA2G4F FYN CNTN1 GRAP	3.79e-05	169	99	5	3c4c3279cd72f39b5e7ff77741950ed3873c0317
ToppCell	facs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJC13 GCNT1 ACSS2 CROT ALDOB	3.79e-05	169	99	5	ee27bcfe3f9a295ec5fb0a375d77d1050e5cbaad
ToppCell	facs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJC13 GCNT1 ACSS2 CROT ALDOB	3.79e-05	169	99	5	922086f218135b734b7d370b871923e50141edce
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 PLA2G4F FYN CNTN1 GRAP	3.79e-05	169	99	5	d6437afa298c280d202ba686338c6d8a37bd7ab7
ToppCell	droplet-Lung-nan-21m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EOGT ERN2 PLA2G4F SCIN CNTN1	4.01e-05	171	99	5	159ce6d5513008532dd7785b915b3fe7440cc4b2
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 CAT CROT SLC25A13 ALDOB	4.12e-05	172	99	5	feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 CAT CROT SLC25A13 ALDOB	4.12e-05	172	99	5	9adfb4a65669cc536343616637058d0a4728013f
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 CAT CROT SLC25A13 ALDOB	4.12e-05	172	99	5	8aed9c113f27d00401c272a3684495a4bc75bd0f
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANGPT2 MMP17 RSPH10B JPH3 GRAP	4.60e-05	176	99	5	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPT1 ACSS2 SLC35D1 SYTL3 SCIN	4.72e-05	177	99	5	9b4c1ca5c6fca9a7a936dad49a04155903ef9c32
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP24 AATK NTM CD47 MMP1	4.85e-05	178	99	5	f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEL1L ANGPT1 SELENBP1 CAT FYN	4.98e-05	179	99	5	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL3 SLFN13 GUCY2D FGR FYN	5.25e-05	181	99	5	ee1c5af8ed75dd8a0ed3152ba5b9a42d2a8c2ae4
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MYH6 VTN SRRM4 SCGN SVOP	5.53e-05	183	99	5	8820cfed27b292bc0bc9cde4005219ed41900552
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ST6GALNAC1 SELENBP1 OAT CAT IRF6	5.68e-05	184	99	5	0efc757d9512d6a8fe8176e977a94e4494ed9778
ToppCell	(7)_Epithelial-H_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ST6GALNAC1 IRF6 CROT SPOCK3 MMP1	5.68e-05	184	99	5	1f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 SELENBP1 OAT ERN2 ALDOB	5.68e-05	184	99	5	c2ca984551baf4becbefbe58bd1889828542b045
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 OAT CAT GCNT1 ALDOB	5.82e-05	185	99	5	3e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 SYTL3 ABHD8 FYN GRAP	5.82e-05	185	99	5	c9ab7a3584d25f0ed73b20919c3dba00f502eac4
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENBP1 OAT CAT GCNT1 ALDOB	5.82e-05	185	99	5	0ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIMD2 SYTL3 SLFN13 FGR FYN	5.98e-05	186	99	5	885aed2472cead81d60c9f3a28c0ff10eb449592
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	CROT SERPINB13 SPOCK3 TRPV4 MMP1	6.13e-05	187	99	5	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIMD2 SYTL3 SLFN13 FGR FYN	6.44e-05	189	99	5	5a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERCC6 LIMD2 SERPINA1 SLFN13 CTR9	6.94e-05	192	99	5	fcdb2e924800457d21e4aaeeedd81dbf80216eed
ToppCell	10x5'-Liver\|World / Manually curated celltypes from each tissue	VTN SERPINA1 FGB FGR ALDOB	7.11e-05	193	99	5	d010d47d763c99e68aede59345392f2a8c77d7ac
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIMD2 SYTL3 SLFN13 FGR FYN	7.11e-05	193	99	5	044fba87c4d10f4943a9f57315920280a4d097e7
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENBP1 CAT ACSS2 SERPINA1 PLA2G4F	7.11e-05	193	99	5	043dd0fc2f93e0bd1ca34ac3e196622b3e91df0f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 SELENBP1 OAT ERN2 SCIN	7.29e-05	194	99	5	40251e6415a62fa55d86f2e8609bf0402e1c1abb
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIMD2 SYTL3 SLFN13 FGR FYN	7.29e-05	194	99	5	3fe32e38c95135d152acb1624fec1623339e144a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ACSS2 ERN2 MCF2L	7.47e-05	195	99	5	c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ACSS2 ERN2 MCF2L	7.47e-05	195	99	5	219c5d0cde7f6082755154f54db221413ec555cb
ToppCell	distal-Epithelial-Proximal_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ST6GALNAC1 ERN2 SERPINB13 SPOCK3 MMP1	7.65e-05	196	99	5	c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-goblet\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ACSS2 ERN2 MCF2L	7.65e-05	196	99	5	c2d17630f7bfc9e727de55e093c17fddac61b61f
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ST6GALNAC1 IRF6 CROT SERPINB13 MMP1	7.65e-05	196	99	5	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	distal-Epithelial-Proximal_Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ST6GALNAC1 ERN2 SERPINB13 SPOCK3 MMP1	7.65e-05	196	99	5	a543d4623096cb3f9170dbf7af52381e77aa435e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OAT IRF6 GCNT1 SERPINA1 FGB	7.65e-05	196	99	5	4deaadb9796b907b7480fb7af5ed76ebad240850
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-goblet-Goblet_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ACSS2 ERN2 MCF2L	7.65e-05	196	99	5	54c30023d04e7265373647f56fc93885804938b0
ToppCell	distal-3-Epithelial-Proximal_Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ST6GALNAC1 ERN2 SERPINB13 SPOCK3 MMP1	7.65e-05	196	99	5	7e1a565dd2da4f375cbce8842ba4fd6c22ac8375
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TRHDE ABCA1 ANGPT1 CALML6 NTM	7.84e-05	197	99	5	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GALNAC1 ERN2 CROT SPOCK3 TRPV4	7.84e-05	197	99	5	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	3'-Broncho-tracheal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 OAT IRF6 SERPINB13 SPOCK3	7.84e-05	197	99	5	5d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GALNAC1 ERN2 SERPINB13 SPOCK3 TRPV4	8.03e-05	198	99	5	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ST6GALNAC1 OAT IRF6 ERN2 SERPINB13	8.03e-05	198	99	5	6e047de63ef59dcb47e4fc06b173b2a02fdcf4c9
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VTN OAT GCNT1 SERPINA1 FGB	8.03e-05	198	99	5	686d973483d027a3ffa2ad4430ba6e50f3d1378e
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SELENBP1 ACSS2 SERPINA1 CD47 PLA2G4F	8.03e-05	198	99	5	85215015bb86ada0e871c413a4ecdc903a3785ca
ToppCell	Epithelial_cells-Basal_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	GCNT1 CROT SERPINB13 SPOCK3 MMP1	8.03e-05	198	99	5	4235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VTN IRF6 GCNT1 SERPINA1 FGB	8.03e-05	198	99	5	0617e015601a3acecf22844c01053671a97cfadb
ToppCell	3'-Broncho-tracheal-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 OAT IRF6 SERPINB13 SPOCK3	8.03e-05	198	99	5	aa6e7218ee6230902854e66c444b544218b30c0e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 OAT ERN2 PTK6 SERPINB13	8.03e-05	198	99	5	3cc9e671f596ef0829684018e4257571fefb6267
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OAT IRF6 GCNT1 SERPINA1 FGB	8.03e-05	198	99	5	ecdef1a0a0b8399e193b922c8ca8c25e63de4a4f
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VTN OAT GCNT1 SERPINA1 FGB	8.03e-05	198	99	5	a76366611f3561fc8aca7d62d1f0a0ea2bef7792
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VTN IRF6 GCNT1 SERPINA1 FGB	8.03e-05	198	99	5	1c598e1351556f61da7b50961dd55f84a317c068
ToppCell	NS-critical-LOC-Myeloid-Neutrophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ABCA1 CIR1 SERPINA1 SLC25A13 FGR	8.03e-05	198	99	5	e56417073e83061a43b9c41d6232d653904c1e90
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VTN OAT GCNT1 SERPINA1 FGB	8.03e-05	198	99	5	8fbc461315986e357a0961a261ed10880637d6ad
ToppCell	NS-critical-LOC-Myeloid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ABCA1 CIR1 SERPINA1 SLC25A13 FGR	8.03e-05	198	99	5	58f2bc88d92550fb0b7c2e46c63c49ec6777001c
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VTN IRF6 GCNT1 SERPINA1 FGB	8.03e-05	198	99	5	0d9bb0530af6af1d9f64baa2f1e77ffc7f0e5233
ToppCell	distal-Epithelial-Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ST6GALNAC1 OAT IRF6 SPOCK3 TRPV4	8.03e-05	198	99	5	dda0bf3a48f738df590ce23b891d82be19e10d66
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SELENBP1 ACSS2 SERPINA1 CD47 PLA2G4F	8.03e-05	198	99	5	38349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ERN2 SERPINA1 FGB	8.22e-05	199	99	5	fb9550bbb1fa206c3132e0a21a646eedb41c281a
ToppCell	5'-Adult\|5' / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACSS2 PTK6 SYTL3 SCIN ALDOB	8.22e-05	199	99	5	8b7b1fcea9a06522fdfab85d0dfd33010ae96d75
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLC35D1 LIMD2 SYTL3 SLFN13 FYN	8.22e-05	199	99	5	3bac69726153e988a7f36613ee280c74d2fa7545
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 IRF6 ERN2 SERPINA1 FGB	8.22e-05	199	99	5	440f47e320c75f49ef47139b46962de68cee8320
ToppCell	Biopsy_Control_(H.)-Epithelial-Basal\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ST6GALNAC1 SCGN SERPINB13 SPOCK3 CNTN1	8.22e-05	199	99	5	6a274a5db02c55bbf31d602b9d5c8394241acdca
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEL1L TRHDE GRB2 SERPINA1 SLFN11	8.22e-05	199	99	5	8e9862907b15809d083216e7d6a0f435015e5d15
ToppCell	Severe_COVID-19-Epithelial-Basal/Club\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ST6GALNAC1 SELENBP1 IRF6 ERN2 SERPINB13	8.22e-05	199	99	5	2a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GALNAC1 IRF6 ERN2 PTK6 SERPINB13	8.41e-05	200	99	5	5f0f67958c9635db53e61f8370a92da6ea3e80fe
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 SELENBP1 OAT ERN2 SERPINB13	8.41e-05	200	99	5	694ebc8cc14f80b6f2f4acec4ce7452d8b816af8
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IRF6 CROT SERPINB13 SPOCK3 MMP1	8.41e-05	200	99	5	9da214f756a03516eaafde00289b90f69623b9f3
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IRF6 CROT SERPINB13 SPOCK3 TRPV4	8.41e-05	200	99	5	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GALNAC1 IRF6 ERN2 PTK6 SERPINB13	8.41e-05	200	99	5	ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCell	Biopsy_Other_PF-Epithelial-Basal\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ST6GALNAC1 IRF6 SERPINB13 SPOCK3 MMP1	8.41e-05	200	99	5	7098ae4b0ea8ba607519eaed8577c577530fc2a1
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GALNAC1 IRF6 SERPINB13 SPOCK3 MMP1	8.41e-05	200	99	5	0594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE ABCA1 ANGPT1 SERPINB13 NTM	8.41e-05	200	99	5	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MCF2 SERPINA1 SLC25A13 FGR	1.14e-04	112	99	4	ef8fdb35a4d295f7e4a0a4029e5965c1f17e413a
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	SPOPL CHD9 CROT SPOCK3	2.34e-04	135	99	4	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYH6 VTN ANGPT2 SULT6B1	2.34e-04	135	99	4	e908aacb72a8c340f06cf5b4a6b70c2faac4d027
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma_Heterologous_Type-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	VTN SLC17A4 SCGN FGB	2.91e-04	143	99	4	bcf702f976ab91f82a5a4beb0b7c74a372c42ae6
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAT CROT SLC25A13 FGB	3.24e-04	147	99	4	00619115b9a1ec2b967c2992043b41974ece63c4
Drug	Sialic acids	ST6GALNAC1 VTN SPOPL SENP3 GCNT1 SERPINA1 NTM CD47 SPOP ALDOB	1.73e-06	329	99	10	CID000349960
Drug	carvedilol	MYH3 MYH6 MYH7B CAT MMP24 MMP1 MMP17	6.69e-06	161	99	7	CID000002585
Drug	chondroitin sulfate	VTN ERCC6 CHERP MCF2 SPOCK3 NTM MMP1 MMP17 CNTN2 CNTN1	1.28e-05	413	99	10	CID000024766
Drug	Fulicin	SERPINA1 FGR	1.87e-05	2	99	2	CID000132035
Drug	thio-phene-2-carbohydrazide	CAT NTM	1.87e-05	2	99	2	CID000073098
Drug	hyaluronan	ST6GALNAC1 LIAS VTN ERCC6 CAT SPOCK3 FGB MMP1	1.97e-05	263	99	8	CID000024759
Drug	neuraminic acid	SPOPL CAT SERPINA1 SPOP ALDOB	2.03e-05	76	99	5	CID000441037
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; HL60; HT_HG-U133A	MYH3 ANGPT2 LIMD2 SPOCK3 NTM FGB SCIN	2.17e-05	193	99	7	3015_UP
Drug	AC1L3U0V	MYH6 GRB2 APEH FYN	2.73e-05	40	99	4	CID000122124
Drug	Betazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A	TRHDE ABCA1 NIPSNAP3B ERAP1 MMP24 SERPINA1 CNOT3	2.73e-05	200	99	7	5445_UP
Drug	trisodium citrate dihydrate	ST6GALNAC1 CAT FGB SNAPC4	3.32e-05	42	99	4	CID000071474
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH3 MYH6 MYH7B	4.19e-06	10	98	3	DOID:0080326 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH3 MYH6 MYH7B	7.65e-06	12	98	3	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH3 MYH6 MYH7B	7.65e-06	12	98	3	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH3 MYH6 MYH7B	9.92e-06	13	98	3	DOID:397 (implicated_via_orthology)
Disease	autosomal recessive nonsyndromic deafness 114 (implicated_via_orthology)	GRB2 GRAP	1.09e-05	2	98	2	DOID:0111642 (implicated_via_orthology)
Disease	autosomal dominant nonsyndromic deafness 25 (implicated_via_orthology)	SLC17A8 TRPV4	1.09e-05	2	98	2	DOID:0110555 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH3 MYH6 MYH7B	1.57e-05	15	98	3	DOID:0050646 (implicated_via_orthology)
Disease	thrombosis (is_implicated_in)	VTN FGB MMP1	1.57e-05	15	98	3	DOID:0060903 (is_implicated_in)
Disease	UV-sensitive syndrome (is_implicated_in)	ERCC6 UVSSA	3.27e-05	3	98	2	DOID:0060240 (is_implicated_in)
Disease	UV-Sensitive Syndrome	ERCC6 UVSSA	3.27e-05	3	98	2	C1833561
Disease	gastric ulcer (biomarker_via_orthology)	ANGPT1 ANGPT2 CAT	4.52e-05	21	98	3	DOID:10808 (biomarker_via_orthology)
Disease	zinc finger protein 175 measurement	VTN SERPINA1	6.52e-05	4	98	2	EFO_0802225
Disease	cardiomyopathy (implicated_via_orthology)	MYH3 MYH6 MYH7B JPH3	9.37e-05	71	98	4	DOID:0050700 (implicated_via_orthology)
Disease	DnaJ homolog subfamily B member 9 measurement	VTN SERPINA1	1.08e-04	5	98	2	EFO_0801540
Disease	synaptosomal-associated protein 25 measurement	VTN SERPINA1	1.08e-04	5	98	2	EFO_0021858
Disease	Ischemic stroke, factor VII measurement	FGB MCF2L JPH3	1.22e-04	29	98	3	EFO_0004619, HP_0002140
Disease	D dimer measurement	GCNT1 FGB CNTN1	1.35e-04	30	98	3	EFO_0004507
Disease	Chronic Obstructive Airway Disease	SERPINA1 TRPV4 MMP1	1.80e-04	33	98	3	C0024117
Disease	Chronic Airflow Obstruction	SERPINA1 TRPV4 MMP1	1.80e-04	33	98	3	C1527303
Disease	myocardial infarction (biomarker_via_orthology)	MYH6 ANGPT1 ANGPT2 CAT MMP1	1.99e-04	160	98	5	DOID:5844 (biomarker_via_orthology)
Disease	testican-3 measurement	VTN SPOCK3	2.27e-04	7	98	2	EFO_0802124
Disease	pancreatitis (biomarker_via_orthology)	HSP90AB4P SERPINA1 FGB	2.98e-04	39	98	3	DOID:4989 (biomarker_via_orthology)
Disease	Hereditary Motor and Sensory Neuropathy Type I	MORC2 TRPV4	3.02e-04	8	98	2	C0751036
Disease	Roussy-Levy Syndrome (disorder)	MORC2 TRPV4	3.02e-04	8	98	2	C0205713
Disease	Charcot-Marie-Tooth Disease, Type Ib	MORC2 TRPV4	3.02e-04	8	98	2	C0270912
Disease	Charcot-Marie-Tooth Disease, Type Ia (disorder)	MORC2 TRPV4	3.02e-04	8	98	2	C0270911
Disease	PH and SEC7 domain-containing protein 1 measurement	VTN SERPINA1	3.02e-04	8	98	2	EFO_0803302
Disease	diabetic retinopathy (biomarker_via_orthology)	VTN ANGPT2 CAT	4.56e-04	45	98	3	DOID:8947 (biomarker_via_orthology)
Disease	osteonecrosis (is_implicated_in)	CAT TRPV4	4.83e-04	10	98	2	DOID:10159 (is_implicated_in)
Disease	myopathy (implicated_via_orthology)	MYH3 MYH6 MYH7B	5.51e-04	48	98	3	DOID:423 (implicated_via_orthology)
Disease	pulmonary emphysema (is_implicated_in)	SERPINA1 MMP1	5.89e-04	11	98	2	DOID:9675 (is_implicated_in)
Disease	endometrial adenocarcinoma (is_marker_for)	ANGPT1 ANGPT2	5.89e-04	11	98	2	DOID:2870 (is_marker_for)
Disease	Charcot-Marie-Tooth Disease	MORC2 TRPV4	7.05e-04	12	98	2	C0007959
Disease	hypertension (is_marker_for)	ANGPT1 SERPINA1 MMP1	7.38e-04	53	98	3	DOID:10763 (is_marker_for)
Disease	Ischemic stroke, fibrinogen measurement	CHD9 FGB JPH3	8.22e-04	55	98	3	EFO_0004623, HP_0002140
Disease	phospholipids in medium HDL measurement	ABCA1 VTN TOMM40L	8.22e-04	55	98	3	EFO_0022295
Disease	Hereditary Motor and Sensory-Neuropathy Type II	MORC2 TRPV4	8.32e-04	13	98	2	C0270914
Disease	osteoprotegerin measurement	VTN SERPINA1	9.68e-04	14	98	2	EFO_0005918
Disease	phospholipids:total lipids ratio	ABCA1 VTN SCGN SERPINA1 TOMM40L	9.80e-04	227	98	5	EFO_0020946
Disease	Liver Cirrhosis, Experimental	CERK ERAP1 OAT GCNT1 CROT SLC25A13 MMP1 FGR FYN	1.11e-03	774	98	9	C0023893
Disease	Ischemic stroke, tissue plasminogen activator measurement	FGB JPH3	1.11e-03	15	98	2	EFO_0004791, HP_0002140
Disease	type 2 diabetes mellitus (is_marker_for)	ANGPT2 CAT FGB MMP1	1.12e-03	136	98	4	DOID:9352 (is_marker_for)
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	FGB JPH3	1.27e-03	16	98	2	EFO_0004792, HP_0002140
Disease	filaggrin gene expression measurement	ZNF254 NTM	1.27e-03	16	98	2	EFO_0020899
Disease	factor XI measurement, Ischemic stroke	FGB JPH3	1.44e-03	17	98	2	EFO_0004694, HP_0002140
Disease	S-6-hydroxywarfarin measurement	EXOC6 SRRM4 CHD9 OAT CD47 SCIN	1.45e-03	368	98	6	EFO_0803326
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	EXOC6 ABCA1 TOMM40L FGB	1.72e-03	153	98	4	EFO_0004611, EFO_0020946
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	EXOC6 ABCA1 SERPINA1 FGB	1.72e-03	153	98	4	EFO_0004611, EFO_0020944
Disease	fibrinogen measurement, coronary artery disease	CHD9 SCGN SERPINA1 FGB	1.76e-03	154	98	4	EFO_0001645, EFO_0004623
Disease	coagulation factor measurement	MCF2L CNTN1	2.00e-03	20	98	2	EFO_0004634
Disease	Disproportionate short stature	SLC35D1 TRPV4 EIF2AK3	2.17e-03	77	98	3	C0878659
Disease	rheumatoid arthritis, ulcerative colitis	APEH SNAPC4	2.20e-03	21	98	2	EFO_0000685, EFO_0000729
Disease	Arthrogryposis	MYH3 ERCC6	2.20e-03	21	98	2	C0003886
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	ABCA1 VTN GRB2 SERPINA1 TOMM40L	2.24e-03	274	98	5	EFO_0004530, EFO_0004612
Disease	total iron binding capacity	DNAJC13 SCGN SERPINA1	2.26e-03	78	98	3	EFO_0006334
Disease	hypertrophic cardiomyopathy (is_implicated_in)	MYH7B MMP1	2.42e-03	22	98	2	DOID:11984 (is_implicated_in)
Disease	carotid artery disease (is_implicated_in)	FGB MMP1	2.42e-03	22	98	2	DOID:3407 (is_implicated_in)
Disease	nephrosis (biomarker_via_orthology)	ANGPT1 ANGPT2	2.42e-03	22	98	2	DOID:2527 (biomarker_via_orthology)
Disease	pulmonary hypertension (biomarker_via_orthology)	ANGPT1 ANGPT2 TRPV4	2.43e-03	80	98	3	DOID:6432 (biomarker_via_orthology)
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH3 MYH6 MYH7B	2.43e-03	80	98	3	DOID:12930 (implicated_via_orthology)
Disease	Alveolitis, Fibrosing	CAT SERPINA1 FYN	2.69e-03	83	98	3	C4721507
Disease	Behcet Syndrome	ERAP1 CAT	2.87e-03	24	98	2	C0004943
Disease	brain stem volume measurement	KATNA1 EIF2AK3	2.87e-03	24	98	2	EFO_0010605
Disease	Pulmonary Fibrosis	CAT SERPINA1 FYN	2.88e-03	85	98	3	C0034069
Disease	3-hydroxybutyrate measurement	ABCA1 SERPINA1	3.12e-03	25	98	2	EFO_0010982

Protein segments in the cluster

Peptide	Gene	Start	Entry
TDIDRVFDWIAYKKG	TRHDE	516	Q9UKU6
AEDIFWKQADFGYAR	EOGT	111	Q5NDL2
GFAVKFYTEDGNWDL	CAT	131	P04040
AFSKKGGHLEWEYQF	EIF2AK3	321	Q9NZJ5
AQYKKDGVDFGKWRA	ALDOB	136	P05062
FALVNYIFFKGKWER	SERPINA1	206	P01009
LREASGKYFLWEEKF	GRAP	111	Q13588
LKNKIWVNEFRYGGF	ABCA1	1521	O95477
GSVDFQRTWKEYKVG	ANGPT2	331	O15123
EDGSLDFQRGWKEYK	ANGPT1	331	Q15389
RYNFDVTKGKIFIEW	ACSS2	81	Q9NR19
FRVFDKEGKGYIDWN	CALML6	116	Q8TD86
ELEEDQFGYWKRSGK	ERCC6	826	Q03468
WKEQLDFFVRLGYEV	ABHD8	191	Q96I13
YFDYEKWGQRKKEGF	CNOT3	726	O75175
KWGQRKKEGFTFEYR	CNOT3	731	O75175
WADGLKYEGDFVKNV	RSPH10B	126	P0C881
WADGLKYEGDFVKNV	RSPH10B2	126	B2RC85
ADGRFVFFKGDKYWV	MMP24	436	Q9Y5R2
RWEPVGKTYFFKGER	MMP24	481	Q9Y5R2
NYDEGFGRKQHKELW	LIMD2	101	Q9BT23
AEEWYFGKIGRKDAE	FGR	141	P09769
AEFQWYKDDKRLIEG	NTM	251	Q9P121
NIGVYEGDRVWLKKF	GUCY2D	551	Q02846
KKVRAVYTEGGWFEE	L3MBTL2	416	Q969R5
AFVEQEWKKGFEVIY	HSP90AB4P	406	Q58FF6
YKTADFGIWERGDKT	PHKA1	176	P46020
DGVFYTGRKQDAWFV	ERN2	121	Q76MJ5
KFWKIGNKERDGEYG	HPS5	206	Q9UPZ3
YKENKFGFRWRVEKE	FRA10AC1	151	Q70Z53
RAEGYFRKWKESNGN	ERAP1	746	Q9NZ08
QDGSVDFGRKWDPYK	FGB	286	P02675
YKREGIDWVFIDFGL	MYH7B	546	A7E2Y1
EFGGRTNKVFHIWKY	NIPSNAP3B	76	Q9BS92
EKFKYWEKVGNELGF	LIAS	326	O43766
KDYVAGREFVAWKDT	PLA2G4F	646	Q68DD2
LRDGAGKYFLWVVKF	GRB2	111	P62993
KWAGVFRDIFEEDNY	EXOC6	431	Q8TAG9
IAQRGIIKFWDEFGY	MORC2	456	Q9Y6X9
YFGEVFEGLWKDRVQ	PTK6	201	Q13882
VHYRGDEKIKGFIWD	CHD9	1541	Q3L8U1
EGWEQNGLYEFFRAK	CHERP	706	Q8IWX8
GFYGDIIKDSEKKRW	CERK	291	Q8TCT0
AEEWYFGKLGRKDAE	FYN	146	P06241
GYIVAFKPFDGEEWK	CNTN1	741	Q12860
ARDKGNFYEASDWFK	CTR9	541	Q6PD62
GYEIRYWKAGDKEAA	CNTN2	846	Q02246
ESEKEWYFGNADKER	DNAJC13	971	O75165
KGDAKKFEIWYNARE	MCF2L	906	O15068
GDNRKFEIWYGEKEE	MCF2	771	P10911
ADIERYEKWIFEFGS	KATNA1	476	O75449
VKWKFKGRDIYTFDG	CD47	56	Q08722
ARFVKWQYFEGDVSK	GCNT1	351	Q02742
YWEKFFQQRGKKAFE	METTL13	16	Q8N6R0
WQRFDADEKGYIEEK	SCGN	21	O76038
FYLIFGRADVQDWAK	SLC17A4	476	Q9Y2C5
QNFRTEDGDWYRKAK	SLFN13	671	Q68D06
EQLGFDYGERFWDIK	EHMT1	1236	Q9H9B1
DYGERFWDIKGKLFS	EHMT1	1241	Q9H9B1
YVDEKIFQNEGRWKG	CROT	341	Q9UKG9
AWTRFGENFIKYEEE	PURG	306	Q9UJV8
IFKAWAVETGKYQEG	IRF6	56	O14896
NVKIKTGEWFYEERA	SYTL3	111	Q4VX76
FLFRKGEVGDWKNLF	SULT6B1	256	Q6IMI4
EDAVEAIGFGKFQWK	SVOP	71	Q8N4V2
AVEGWNEKFGEAYKK	UVSSA	116	Q2YD98
LKYFQKAAEQGWVDG	SEL1L	471	Q9UBV2
GFLYEKIGFEWAAAI	SLC18B1	396	Q6NT16
NFEYKWEAGRGAEAF	AATK	476	Q6ZMQ8
KIVFFKGDRYWVFKD	MMP17	396	Q9ULZ9
KGDRYWVFKDNNVEE	MMP17	401	Q9ULZ9
DRDEVRFFKGNKYWA	MMP1	336	P03956
DWRDKDQSDGFGKVY	SCIN	346	Q9Y6U3
RAEKIWKYFGKNDDD	RCVRN	151	P35243
LEGGFKISYEWAVRF	POGZ	1061	Q7Z3K3
RWDFEEKYSFEIGGL	ST6GALNAC1	261	Q9NSC7
QNFRTEDGDWYGKAK	SLFN11	671	Q7Z7L1
RFYKNEGGTWSVEKV	SELENBP1	276	Q13228
EYKKEGIEWTFIDFG	MYH3	501	P11055
YFTGDAQKAVEFEGW	SLC35D1	236	Q9NTN3
EYKKEGIEWTFIDFG	MYH6	501	P13533
YKAKIVFAAGNFWGR	OAT	166	P04181
IKGDQFVFYEDWGEN	APEH	201	P13798
ELLQRWFYIDFGGVK	SLC25A13	601	Q9UJS0
FEWQKGAPREKYAKD	CIR1	96	Q86X95
KDRGFEYDGKINAWD	NLN	346	Q9BYT8
KDRLDFHQGWKGYFK	SENP3	506	Q9H4L4
FRQEKAVWIKYGAFL	PDCD11	1721	Q14690
VYFKGQWDREFKKEN	SERPINB13	181	Q9UIV8
RAYRFVQGKDWGFKK	SPOPL	121	Q6IQ16
RAYRFVQGKDWGFKK	SPOP	121	O43791
QGEKQLFEKFWRGTF	SRRM4	6	A7MD48
YDKEVGQWNKFRDEV	SPOCK3	51	Q9BQ16
ARDFGGAVQDYFKWK	THUMPD3	246	Q9BV44
KFLTWQFDGEYRGDD	TOMM40L	131	Q969M1
VAKYGEQDWFKIREE	SNAPC4	416	Q5SXM2
FGDINYQEFAKRLWG	EFTUD2	331	Q15029
GEDYREKQKIAFTEW	SMARCA5	716	O60264
LFKGSQYWRFEDGVL	VTN	221	P04004
DKWRKFGAVSFYINV	TRPV4	461	Q9HBA0
GEQPYKWEKFGKAFN	ZNF254	626	O75437
IFYGVFASGEKQEWA	SLC17A8	496	Q8NDX2
ETYVGEWKNDKRSGF	JPH3	286	Q8WXH2