Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N6-methyladenosine-containing RNA reader activity	YTHDF1 YTHDF3	4.09e-05	15	13	2	GO:1990247
GeneOntologyMolecularFunction	protein-RNA adaptor activity	YTHDF1 YTHDF3	1.07e-04	24	13	2	GO:0140517
GeneOntologyMolecularFunction	chromatin binding	DLX2 ZNF609 POLR2A RUNX2	1.02e-03	739	13	4	GO:0003682
GeneOntologyMolecularFunction	promoter-specific chromatin binding	ZNF609 POLR2A	1.29e-03	83	13	2	GO:1990841
GeneOntologyMolecularFunction	ribosome binding	YTHDF1 YTHDF3	2.68e-03	120	13	2	GO:0043022
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	PAX8 DLX2 RUNX2	5.09e-03	560	13	3	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	PAX8 DLX2 RUNX2	5.24e-03	566	13	3	GO:0001216
GeneOntologyMolecularFunction	ribonucleoprotein complex binding	YTHDF1 YTHDF3	7.67e-03	206	13	2	GO:0043021
GeneOntologyBiologicalProcess	odontogenesis of dentin-containing tooth	LRP6 DLX2 RUNX2	3.74e-05	107	13	3	GO:0042475
GeneOntologyBiologicalProcess	regulation of animal organ morphogenesis	LRP6 PAX8 RUNX2	4.06e-05	110	13	3	GO:2000027
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	LRP6 PAX8 DLX2 RUNX2	5.22e-05	351	13	4	GO:0048562
GeneOntologyBiologicalProcess	odontogenesis	LRP6 DLX2 RUNX2	1.04e-04	151	13	3	GO:0042476
GeneOntologyBiologicalProcess	positive regulation of neuron migration	ARHGAP32 ZNF609	1.09e-04	25	13	2	GO:2001224
GeneOntologyBiologicalProcess	positive regulation of translational initiation	YTHDF1 YTHDF3	1.47e-04	29	13	2	GO:0045948
GeneOntologyBiologicalProcess	stress granule assembly	YTHDF1 YTHDF3	2.28e-04	36	13	2	GO:0034063
GeneOntologyBiologicalProcess	embryonic forelimb morphogenesis	LRP6 RUNX2	2.41e-04	37	13	2	GO:0035115
GeneOntologyBiologicalProcess	embryonic organ development	LRP6 PAX8 DLX2 RUNX2	3.18e-04	561	13	4	GO:0048568
GeneOntologyBiologicalProcess	forelimb morphogenesis	LRP6 RUNX2	4.07e-04	48	13	2	GO:0035136
GeneOntologyBiologicalProcess	cartilage development	LRP6 DLX2 RUNX2	4.23e-04	243	13	3	GO:0051216
GeneOntologyBiologicalProcess	positive regulation of cell differentiation	PAX8 ARHGAP32 DLX2 ZNF609 RUNX2	4.55e-04	1141	13	5	GO:0045597
GeneOntologyBiologicalProcess	embryonic cranial skeleton morphogenesis	DLX2 RUNX2	4.78e-04	52	13	2	GO:0048701
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	LRP6 PAX8 DLX2	5.04e-04	258	13	3	GO:0001763
GeneOntologyBiologicalProcess	skeletal system morphogenesis	LRP6 DLX2 RUNX2	6.20e-04	277	13	3	GO:0048705
GeneOntologyBiologicalProcess	regulation of neuron migration	ARHGAP32 ZNF609	6.79e-04	62	13	2	GO:2001222
GeneOntologyBiologicalProcess	forebrain generation of neurons	LRP6 DLX2	7.46e-04	65	13	2	GO:0021872
GeneOntologyBiologicalProcess	positive regulation of ossification	LRP6 RUNX2	7.69e-04	66	13	2	GO:0045778
GeneOntologyBiologicalProcess	embryonic morphogenesis	LRP6 PAX8 DLX2 RUNX2	7.89e-04	713	13	4	GO:0048598
GeneOntologyBiologicalProcess	positive regulation of stem cell proliferation	LRP6 RUNX2	9.14e-04	72	13	2	GO:2000648
GeneOntologyBiologicalProcess	regulation of morphogenesis of an epithelium	LRP6 PAX8	1.02e-03	76	13	2	GO:1905330
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	LRP6 PAX8 DLX2 ZNF609 RUNX2	1.12e-03	1390	13	5	GO:0045944
GeneOntologyBiologicalProcess	connective tissue development	LRP6 DLX2 RUNX2	1.15e-03	343	13	3	GO:0061448
GeneOntologyBiologicalProcess	cranial skeletal system development	DLX2 RUNX2	1.24e-03	84	13	2	GO:1904888
GeneOntologyBiologicalProcess	negative regulation of muscle cell apoptotic process	LRP6 PAX8	1.33e-03	87	13	2	GO:0010656
GeneOntologyBiologicalProcess	regulation of translational initiation	YTHDF1 YTHDF3	1.45e-03	91	13	2	GO:0006446
GeneOntologyBiologicalProcess	ventricular septum development	LRP6 PAX8	1.45e-03	91	13	2	GO:0003281
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	TENM1 YTHDF1 LRP6 ARHGAP32	1.49e-03	846	13	4	GO:0120035
GeneOntologyBiologicalProcess	regulation of cell projection organization	TENM1 YTHDF1 LRP6 ARHGAP32	1.61e-03	863	13	4	GO:0031344
GeneOntologyBiologicalProcess	positive regulation of protein polymerization	TENM1 SLAIN2	1.82e-03	102	13	2	GO:0032273
GeneOntologyBiologicalProcess	embryonic skeletal system morphogenesis	DLX2 RUNX2	2.08e-03	109	13	2	GO:0048704
GeneOntologyBiologicalProcess	regulation of stem cell proliferation	LRP6 RUNX2	2.47e-03	119	13	2	GO:0072091
GeneOntologyBiologicalProcess	bone morphogenesis	LRP6 RUNX2	2.68e-03	124	13	2	GO:0060349
GeneOntologyBiologicalProcess	regionalization	LRP6 PAX8 DLX2	2.97e-03	478	13	3	GO:0003002
GeneOntologyBiologicalProcess	translational initiation	YTHDF1 YTHDF3	3.03e-03	132	13	2	GO:0006413
GeneOntologyBiologicalProcess	cardiac septum development	LRP6 PAX8	3.12e-03	134	13	2	GO:0003279
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	TENM1 LRP6 ARHGAP32	3.27e-03	494	13	3	GO:0031346
GeneOntologyBiologicalProcess	regulation of muscle cell apoptotic process	LRP6 PAX8	3.44e-03	141	13	2	GO:0010660
GeneOntologyBiologicalProcess	regulation of ossification	LRP6 RUNX2	3.74e-03	147	13	2	GO:0030278
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	LRP6 PAX8 ARHGAP32 RUNX2	3.78e-03	1090	13	4	GO:0022603
GeneOntologyBiologicalProcess	embryonic limb morphogenesis	LRP6 RUNX2	3.79e-03	148	13	2	GO:0030326
GeneOntologyBiologicalProcess	embryonic appendage morphogenesis	LRP6 RUNX2	3.79e-03	148	13	2	GO:0035113
GeneOntologyBiologicalProcess	embryonic skeletal system development	DLX2 RUNX2	3.79e-03	148	13	2	GO:0048706
GeneOntologyBiologicalProcess	regulation of cell development	LRP6 ARHGAP32 DLX2 ZNF609	3.84e-03	1095	13	4	GO:0060284
GeneOntologyBiologicalProcess	muscle cell apoptotic process	LRP6 PAX8	3.89e-03	150	13	2	GO:0010657
MousePheno	growth retardation of molars	LRP6 RUNX2	1.89e-05	8	12	2	MP:0000128
MousePheno	small molars	LRP6 RUNX2	4.44e-05	12	12	2	MP:0006402
MousePheno	abnormal neurocranium morphology	LRP6 PAX8 DLX2 RUNX2	5.88e-05	269	12	4	MP:0000074
MousePheno	delayed cranial suture closure	LRP6 RUNX2	6.11e-05	14	12	2	MP:0010743
MousePheno	absent stapedial artery	PAX8 DLX2	9.12e-05	17	12	2	MP:0004666
MousePheno	short limbs	LRP6 PAX8 RUNX2	1.02e-04	111	12	3	MP:0000547
MousePheno	abnormal stapedial artery morphology	PAX8 DLX2	1.27e-04	20	12	2	MP:0004665
MousePheno	increased thyroid-stimulating hormone level	PAX8 RUNX2	1.27e-04	20	12	2	MP:0005135
MousePheno	abnormal basicranium morphology	PAX8 DLX2 RUNX2	1.38e-04	123	12	3	MP:0010029
MousePheno	decreased activity of thyroid gland	PAX8 RUNX2	1.41e-04	21	12	2	MP:0003503
MousePheno	delayed bone ossification	LRP6 PAX8 RUNX2	1.52e-04	127	12	3	MP:0000060
MousePheno	small incisors	LRP6 RUNX2	1.55e-04	22	12	2	MP:0030079
MousePheno	abnormal thyroid follicle morphology	PAX8 RUNX2	1.69e-04	23	12	2	MP:0004696
MousePheno	decreased triiodothyronine level	PAX8 RUNX2	1.69e-04	23	12	2	MP:0005473
MousePheno	microdontia	LRP6 RUNX2	2.17e-04	26	12	2	MP:0030088
MousePheno	delayed intramembranous bone ossification	LRP6 RUNX2	2.52e-04	28	12	2	MP:0003420
MousePheno	abnormal thyroid gland physiology	PAX8 RUNX2	2.90e-04	30	12	2	MP:0002876
MousePheno	abnormal stapes morphology	PAX8 DLX2	3.10e-04	31	12	2	MP:0005107
MousePheno	abnormal thyroid-stimulating hormone level	PAX8 RUNX2	3.51e-04	33	12	2	MP:0003971
MousePheno	abnormal triiodothyronine level	PAX8 RUNX2	3.73e-04	34	12	2	MP:0005472
MousePheno	abnormal forelimb morphology	LRP6 PAX8 RUNX2	4.38e-04	182	12	3	MP:0000550
MousePheno	decreased circulating thyroxine level	PAX8 RUNX2	4.67e-04	38	12	2	MP:0005478
MousePheno	abnormal zygomatic bone morphology	DLX2 RUNX2	5.44e-04	41	12	2	MP:0005270
MousePheno	decreased circulating levels of thyroid hormone	PAX8 RUNX2	5.98e-04	43	12	2	MP:0003351
MousePheno	decreased bone mineral density of femur	PAX8 RUNX2	7.15e-04	47	12	2	MP:0020010
MousePheno	abnormal circulating thyroxine level	PAX8 RUNX2	8.41e-04	51	12	2	MP:0005475
MousePheno	decreased thyroxine level	PAX8 RUNX2	8.41e-04	51	12	2	MP:0005471
MousePheno	abnormal molar morphology	LRP6 RUNX2	8.41e-04	51	12	2	MP:0002689
MousePheno	abnormal eyelid morphology	LRP6 PAX8 RUNX2	9.00e-04	233	12	3	MP:0001340
MousePheno	delayed endochondral bone ossification	PAX8 RUNX2	9.43e-04	54	12	2	MP:0003419
MousePheno	abnormal middle ear ossicle morphology	PAX8 DLX2	1.01e-03	56	12	2	MP:0005105
MousePheno	abnormal basisphenoid bone morphology	DLX2 RUNX2	1.05e-03	57	12	2	MP:0000106
MousePheno	abnormal intramembranous bone ossification	LRP6 RUNX2	1.20e-03	61	12	2	MP:0008273
MousePheno	abnormal bone mineral density of femur	PAX8 RUNX2	1.28e-03	63	12	2	MP:0020009
MousePheno	abnormal thyroxine level	PAX8 RUNX2	1.41e-03	66	12	2	MP:0005469
MousePheno	abnormal temporal bone morphology	PAX8 DLX2	1.41e-03	66	12	2	MP:0005272
MousePheno	abnormal outer hair cell stereociliary bundle morphology	LRP6 PAX8	1.49e-03	68	12	2	MP:0004527
MousePheno	cleft palate	LRP6 DLX2 RUNX2	1.68e-03	289	12	3	MP:0000111
MousePheno	oral cleft	LRP6 DLX2 RUNX2	1.71e-03	291	12	3	MP:0021164
MousePheno	abnormal thyroid hormone level	PAX8 RUNX2	1.76e-03	74	12	2	MP:0005468
MousePheno	decreased compact bone thickness	PAX8 RUNX2	2.21e-03	83	12	2	MP:0000135
MousePheno	abnormal palate morphology	LRP6 DLX2 RUNX2	2.26e-03	321	12	3	MP:0003755
MousePheno	abnormal thyroid gland morphology	PAX8 RUNX2	2.43e-03	87	12	2	MP:0000681
MousePheno	abnormal cochlear hair cell stereociliary bundle morphology	LRP6 PAX8	2.65e-03	91	12	2	MP:0004521
MousePheno	abnormal forelimb stylopod morphology	PAX8 RUNX2	2.71e-03	92	12	2	MP:0003854
MousePheno	abnormal humerus morphology	PAX8 RUNX2	2.71e-03	92	12	2	MP:0005296
MousePheno	abnormal middle ear morphology	PAX8 DLX2	2.71e-03	92	12	2	MP:0000049
MousePheno	abnormal cranial blood vasculature morphology	PAX8 DLX2	2.89e-03	95	12	2	MP:0014012
MousePheno	abnormal sphenoid bone morphology	DLX2 RUNX2	2.89e-03	95	12	2	MP:0000104
MousePheno	abnormal adaptive thermogenesis	LRP6 RUNX2	2.95e-03	96	12	2	MP:0011019
MousePheno	decreased amino acid level	PAX8 RUNX2	3.01e-03	97	12	2	MP:0014528
MousePheno	decreased bone mass	LRP6 RUNX2	3.19e-03	100	12	2	MP:0004016
MousePheno	decreased bone volume	PAX8 RUNX2	3.19e-03	100	12	2	MP:0010876
MousePheno	abnormal endochondral bone ossification	PAX8 RUNX2	3.71e-03	108	12	2	MP:0008272
MousePheno	abnormal tooth development	LRP6 RUNX2	3.71e-03	108	12	2	MP:0000116
MousePheno	abnormal incisor morphology	LRP6 RUNX2	3.85e-03	110	12	2	MP:0005358
MousePheno	abnormal cranium morphology	LRP6 PAX8 DLX2 RUNX2	3.86e-03	813	12	4	MP:0000438
MousePheno	abnormal bone ossification	LRP6 PAX8 RUNX2	4.07e-03	395	12	3	MP:0008271
MousePheno	abnormal craniofacial bone morphology	LRP6 PAX8 DLX2 RUNX2	4.11e-03	827	12	4	MP:0002116
MousePheno	abnormal joint morphology	LRP6 DLX2 RUNX2	4.13e-03	397	12	3	MP:0002932
Domain	YTH	YTHDF1 YTHDF3	4.47e-06	5	13	2	PS50882
Domain	YTH_domain	YTHDF1 YTHDF3	4.47e-06	5	13	2	IPR007275
Domain	YTH	YTHDF1 YTHDF3	4.47e-06	5	13	2	PF04146
Domain	-	TENM1 LRP6	3.27e-04	39	13	2	2.120.10.30
Domain	6-blade_b-propeller_TolB-like	TENM1 LRP6	4.55e-04	46	13	2	IPR011042
Domain	EGF	TENM1 LRP6	1.12e-02	235	13	2	SM00181
Domain	EGF_3	TENM1 LRP6	1.12e-02	235	13	2	PS50026
Domain	EGF-like_dom	TENM1 LRP6	1.25e-02	249	13	2	IPR000742
Domain	EGF_1	TENM1 LRP6	1.31e-02	255	13	2	PS00022
Domain	EGF-like_CS	TENM1 LRP6	1.37e-02	261	13	2	IPR013032
Domain	EGF_2	TENM1 LRP6	1.41e-02	265	13	2	PS01186
Domain	Homeodomain-like	PAX8 DLX2	2.16e-02	332	13	2	IPR009057
Pubmed	Cytoplasmic m6A reader YTHDF3 promotes mRNA translation.	YTHDF1 YTHDF3	1.29e-07	2	13	2	28106076
Pubmed	Deletion of YTHDF1 (not YTHDF3) reduced brain and gut damage after traumatic brain injury.	YTHDF1 YTHDF3	1.29e-07	2	13	2	39081030
Pubmed	The inhibition of YTHDF3/m6A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer.	LRP6 YTHDF3	1.29e-07	2	13	2	38250152
Pubmed	Micro-RNA378a-3p Induces Apoptosis in Sarcomatoid Renal Cell Carcinoma and Regulates POLR2A and RUNX2 Expression.	POLR2A RUNX2	3.87e-07	3	13	2	35093879
Pubmed	YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.	YTHDF1 YTHDF3	3.87e-07	3	13	2	28106072
Pubmed	YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation.	YTHDF1 YTHDF3	3.87e-07	3	13	2	35508130
Pubmed	Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration.	YTHDF1 YTHDF3	3.87e-07	3	13	2	34497675
Pubmed	A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.	YTHDF1 YTHDF3	3.87e-07	3	13	2	32492408
Pubmed	Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis.	DLX2 RUNX2	3.87e-07	3	13	2	29242628
Pubmed	Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter.	DLX2 RUNX2	3.87e-07	3	13	2	16115867
Pubmed	m6A-binding YTHDF proteins promote stress granule formation.	YTHDF1 YTHDF3	3.87e-07	3	13	2	32451507
Pubmed	m6A enhances the phase separation potential of mRNA.	YTHDF1 YTHDF3	3.87e-07	3	13	2	31292544
Pubmed	N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression.	YTHDF1 YTHDF3	3.87e-07	3	13	2	27371828
Pubmed	The role of Lrp5/6 in cardiac valve disease: experimental hypercholesterolemia in the ApoE-/- /Lrp5-/- mice.	LRP6 RUNX2	7.74e-07	4	13	2	21678468
Pubmed	N6-methyladenosine-dependent regulation of messenger RNA stability.	YTHDF1 YTHDF3	7.74e-07	4	13	2	24284625
Pubmed	Context-dependent functional compensation between Ythdf m6A reader proteins.	YTHDF1 YTHDF3	1.29e-06	5	13	2	32943573
Pubmed	Spatio-temporal expression of Pbx3 during mouse organogenesis.	DLX2 RUNX2	1.93e-06	6	13	2	16434237
Pubmed	Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I.	DLX2 RUNX2	3.61e-06	8	13	2	27680507
Pubmed	Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1.	DLX2 RUNX2	3.61e-06	8	13	2	12810588
Pubmed	Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo.	LRP6 RUNX2	5.79e-06	10	13	2	21924256
Pubmed	Human transcription factor protein interaction networks.	YTHDF1 LRP6 PAX8 ARHGAP32 ZNF609 YTHDF3	6.37e-06	1429	13	6	35140242
Pubmed	SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.	DLX2 RUNX2	1.00e-05	13	13	2	16751105
Pubmed	LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia.	LRP6 PAX8	1.00e-05	13	13	2	26047795
Pubmed	Requirement for Twist1 in frontonasal and skull vault development in the mouse embryo.	DLX2 RUNX2	1.17e-05	14	13	2	19414008
Pubmed	The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development.	DLX2 RUNX2	1.17e-05	14	13	2	12000792
Pubmed	R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis.	LRP6 DLX2	1.35e-05	15	13	2	18256198
Pubmed	Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development.	POLR2A RUNX2	1.75e-05	17	13	2	21494559
Pubmed	Specific inactivation of Twist1 in the mandibular arch neural crest cells affects the development of the ramus and reveals interactions with hand2.	DLX2 RUNX2	1.75e-05	17	13	2	22411303
Pubmed	Wnt signaling in the murine diastema.	LRP6 RUNX2	1.75e-05	17	13	2	21531785
Pubmed	The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development.	LRP6 PAX8	1.97e-05	18	13	2	33192541
Pubmed	Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis.	DLX2 RUNX2	1.97e-05	18	13	2	21558373
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	ZNF609 YTHDF3 POLR2A SEC31A	2.17e-05	472	13	4	38943005
Pubmed	m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs.	YTHDF1 YTHDF3	2.20e-05	19	13	2	36039295
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	YTHDF1 SLAIN2 YTHDF3 POLR2A SEC31A	2.47e-05	1038	13	5	26673895
Pubmed	Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases.	PAX8 DLX2	2.97e-05	22	13	2	33711282
Pubmed	Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants.	LRP6 DLX2	2.97e-05	22	13	2	15342729
Pubmed	Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin.	POLR2A RUNX2	3.54e-05	24	13	2	32186512
Pubmed	The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.	YTHDF1 YTHDF3	3.54e-05	24	13	2	35179492
Pubmed	The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.	YTHDF1 YTHDF3	3.85e-05	25	13	2	35874829
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	TENM1 ARHGAP32 POLR2A SEC31A	4.01e-05	552	13	4	10737800
Pubmed	A dual role for Ikk alpha in tooth development.	DLX2 RUNX2	4.17e-05	26	13	2	14960276
Pubmed	Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells.	YTHDF1 YTHDF3	7.62e-05	35	13	2	37269288
Pubmed	ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw.	DLX2 RUNX2	7.62e-05	35	13	2	28069742
Pubmed	Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.	YTHDF1 ZNF609 POLR2A	1.12e-04	260	13	3	36199071
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	YTHDF1 SLAIN2 YTHDF3 POLR2A	1.14e-04	723	13	4	34133714
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	YTHDF1 ZNF609 YTHDF3 SEC31A	1.15e-04	724	13	4	36232890
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	YTHDF1 ZNF609 YTHDF3 POLR2A	1.20e-04	733	13	4	34672954
Pubmed	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	PAX8 DLX2 RUNX2	2.28e-04	331	13	3	20634891
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	PAX8 DLX2 POLR2A RUNX2	2.39e-04	877	13	4	20211142
Pubmed	Report and abstracts of the Fourth International Workshop on Human Chromosome 2 Mapping 1996.	PAX8 DLX2	3.16e-04	71	13	2	8751373
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	YTHDF1 ZNF609 YTHDF3 POLR2A	3.30e-04	954	13	4	36373674
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	LRP6 DLX2 RUNX2	3.49e-04	383	13	3	19453261
Pubmed	Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.	SLAIN2 POLR2A	3.52e-04	75	13	2	29459360
Interaction	CNOT1 interactions	YTHDF1 YTHDF3 POLR2A TEX13A	3.30e-05	305	13	4	int:CNOT1
Interaction	CNOT11 interactions	YTHDF1 YTHDF3 TEX13A	4.59e-05	112	13	3	int:CNOT11
Interaction	CNOT7 interactions	YTHDF1 YTHDF3 TEX13A	8.92e-05	140	13	3	int:CNOT7
Interaction	CNOT10 interactions	YTHDF1 YTHDF3 TEX13A	9.11e-05	141	13	3	int:CNOT10
Interaction	CPEB4 interactions	YTHDF1 ARHGAP32 YTHDF3	1.23e-04	156	13	3	int:CPEB4
Interaction	EPHA8 interactions	YTHDF1 YTHDF3 SEC31A	1.56e-04	169	13	3	int:EPHA8
Interaction	CEP85 interactions	YTHDF1 ARHGAP32 YTHDF3	1.56e-04	169	13	3	int:CEP85
Interaction	ISX interactions	YTHDF1 ZNF609	1.77e-04	31	13	2	int:ISX
Interaction	CNOT2 interactions	YTHDF1 YTHDF3 TEX13A	1.82e-04	178	13	3	int:CNOT2
Interaction	ZFP36 interactions	YTHDF1 ARHGAP32 YTHDF3	1.91e-04	181	13	3	int:ZFP36
Interaction	ALG13 interactions	YTHDF1 ZNF609 YTHDF3	1.97e-04	183	13	3	int:ALG13
Interaction	DZIP3 interactions	YTHDF1 ARHGAP32 YTHDF3	1.97e-04	183	13	3	int:DZIP3
Interaction	AGO1 interactions	YTHDF1 YTHDF3 POLR2A	1.97e-04	183	13	3	int:AGO1
Interaction	QKI interactions	YTHDF1 YTHDF3 POLR2A	2.20e-04	190	13	3	int:QKI
Interaction	MSX2 interactions	YTHDF1 DLX2 RUNX2	2.38e-04	195	13	3	int:MSX2
Interaction	PDPK1 interactions	POLR2A SEC31A RUNX2	2.67e-04	203	13	3	int:PDPK1
Interaction	CNOT3 interactions	YTHDF1 YTHDF3 TEX13A	2.83e-04	207	13	3	int:CNOT3
Interaction	TDRD3 interactions	YTHDF1 YTHDF3 POLR2A	3.04e-04	212	13	3	int:TDRD3
Interaction	SMURF1 interactions	SLAIN2 ARHGAP32 POLR2A RUNX2	3.09e-04	544	13	4	int:SMURF1
Interaction	MEN1 interactions	YTHDF1 ZNF609 YTHDF3 POLR2A RUNX2	3.14e-04	1029	13	5	int:MEN1
Interaction	KLK2 interactions	LRP6 POLR2A	3.26e-04	42	13	2	int:KLK2
Interaction	ACOX3 interactions	YTHDF1 RUNX2	3.26e-04	42	13	2	int:ACOX3
Interaction	CNOT9 interactions	YTHDF1 YTHDF3 TEX13A	3.91e-04	231	13	3	int:CNOT9
Interaction	FURIN interactions	YTHDF1 YTHDF3 SEC31A	5.21e-04	255	13	3	int:FURIN
Interaction	COPS2 interactions	SLAIN2 LRP6 POLR2A	5.39e-04	258	13	3	int:COPS2
Interaction	LSM14A interactions	YTHDF1 YTHDF3 SEC31A	5.52e-04	260	13	3	int:LSM14A
Interaction	PRRC2B interactions	YTHDF1 PAX8 YTHDF3	5.83e-04	265	13	3	int:PRRC2B
Interaction	KLK3 interactions	LRP6 POLR2A	6.66e-04	60	13	2	int:KLK3
Interaction	HES1 interactions	POLR2A RUNX2	7.57e-04	64	13	2	int:HES1
Interaction	SKP2 interactions	PAX8 POLR2A RUNX2	8.04e-04	296	13	3	int:SKP2
Interaction	CEP128 interactions	YTHDF1 SLAIN2 POLR2A	8.12e-04	297	13	3	int:CEP128
Interaction	EIF4ENIF1 interactions	YTHDF1 YTHDF3 POLR2A	8.36e-04	300	13	3	int:EIF4ENIF1
Interaction	GCM1 interactions	YTHDF1 ZNF609	8.54e-04	68	13	2	int:GCM1
Interaction	CTH interactions	YTHDF1 SEC31A	9.05e-04	70	13	2	int:CTH
Interaction	B9D2 interactions	YTHDF1 YTHDF3	9.84e-04	73	13	2	int:B9D2
Interaction	SMG7 interactions	YTHDF1 ZNF609 YTHDF3	9.99e-04	319	13	3	int:SMG7
Interaction	CNOT8 interactions	YTHDF3 TEX13A	1.01e-03	74	13	2	int:CNOT8
Interaction	MUSK interactions	ARHGAP32 SEC31A	1.01e-03	74	13	2	int:MUSK
Interaction	SETD1B interactions	ZNF609 POLR2A	1.04e-03	75	13	2	int:SETD1B
Interaction	SECISBP2 interactions	YTHDF1 YTHDF3	1.12e-03	78	13	2	int:SECISBP2
Interaction	BTRC interactions	YTHDF1 ZNF609 YTHDF3 POLR2A	1.17e-03	775	13	4	int:BTRC
Interaction	CARMIL1 interactions	SLAIN2 SEC31A	1.24e-03	82	13	2	int:CARMIL1
Interaction	WAC interactions	SLAIN2 POLR2A	1.27e-03	83	13	2	int:WAC
Interaction	NR0B2 interactions	POLR2A RUNX2	1.27e-03	83	13	2	int:NR0B2
Interaction	R3HDM1 interactions	YTHDF1 YTHDF3	1.30e-03	84	13	2	int:R3HDM1
Interaction	PAX2 interactions	PAX8 ZNF609	1.33e-03	85	13	2	int:PAX2
Interaction	IFITM1 interactions	YTHDF1 YTHDF3 SEC31A	1.36e-03	355	13	3	int:IFITM1
Interaction	MEF2D interactions	PAX8 RUNX2	1.39e-03	87	13	2	int:MEF2D
Interaction	CNOT6L interactions	YTHDF3 TEX13A	1.59e-03	93	13	2	int:CNOT6L
Interaction	GRIN2A interactions	LRP6 ARHGAP32	1.59e-03	93	13	2	int:GRIN2A
Interaction	ZNF608 interactions	PAX8 ZNF609	1.59e-03	93	13	2	int:ZNF608
Interaction	DMRTB1 interactions	YTHDF1 YTHDF3	1.62e-03	94	13	2	int:DMRTB1
Interaction	DCAF4 interactions	YTHDF1 ARHGAP32 YTHDF3	1.63e-03	378	13	3	int:DCAF4
Interaction	INTS14 interactions	ZNF609 POLR2A	1.66e-03	95	13	2	int:INTS14
Interaction	CTSG interactions	YTHDF1 LRP6	1.66e-03	95	13	2	int:CTSG
Interaction	CLEC11A interactions	YTHDF1 ARHGAP32	1.69e-03	96	13	2	int:CLEC11A
Interaction	MKRN2 interactions	PAX8 DLX2 YTHDF3	1.72e-03	385	13	3	int:MKRN2
Interaction	SOX9 interactions	ZNF609 RUNX2	1.73e-03	97	13	2	int:SOX9
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_3DY_DN	YTHDF1 ZNF609 SEC31A RUNX2	4.62e-05	432	13	4	M41149
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	TENM1 SLAIN2 DLX2 YTHDF3 RUNX2	9.24e-05	836	13	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 DLX2 RUNX2	1.64e-05	176	13	3	682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TENM1 ZNF609 RUNX2	2.02e-05	189	13	3	e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 DLX2 RUNX2	2.19e-05	194	13	3	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	TENM1 DLX2	6.04e-04	127	13	2	9071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TENM1 SLAIN2	8.52e-04	151	13	2	9ebfbdccc9656fce8990d06622f225009633f07c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TENM1 SLAIN2	8.52e-04	151	13	2	29d91a7d1470121af45fb8bb35175f2acced4551
ToppCell	facs-Spleen-nan-24m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 RUNX2	8.86e-04	154	13	2	bd283c2367afb99294e7576a0c0167eb7c69ad6b
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	YTHDF3 RUNX2	9.32e-04	158	13	2	b0508a600994090c6aafd8d779437190a33ad821
ToppCell	facs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	YTHDF3 RUNX2	9.32e-04	158	13	2	a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCell	critical-Epithelial-unknown_epithelial\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DLX2 POLR2A	9.67e-04	161	13	2	594cf3245ec065a7685db81cd8ba2cee8d42caac
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLAIN2 ZNF609	9.91e-04	163	13	2	d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TENM1 ZNF609	9.91e-04	163	13	2	e4077e587895c85bc806be05ff5d451088e39468
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TENM1 PAX8	1.00e-03	164	13	2	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 RUNX2	1.03e-03	166	13	2	1ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.03e-03	166	13	2	6e6075d0c913e2516083f6dcab21d5878bcef7a4
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 RUNX2	1.03e-03	166	13	2	4cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.03e-03	166	13	2	4fbe44e0aea197893614cd55f83119aa0f73ee53
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TENM1 DLX2	1.05e-03	168	13	2	f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.09e-03	171	13	2	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM1 DLX2	1.10e-03	172	13	2	8d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell	NS-critical-d_16-33-Epithelial-unknown_epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DLX2 POLR2A	1.10e-03	172	13	2	c0b5e4889aef2f168d9f6db19a63b24bfd249316
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 RUNX2	1.12e-03	173	13	2	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.12e-03	173	13	2	2e35bf2b5534a289d93a09faae660f665c131062
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 RUNX2	1.12e-03	173	13	2	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.14e-03	175	13	2	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.14e-03	175	13	2	11f49f00e000cbc137e3540a6d6805cde21d96e6
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 ZNF609	1.14e-03	175	13	2	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.15e-03	176	13	2	322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.15e-03	176	13	2	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.15e-03	176	13	2	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.15e-03	176	13	2	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.17e-03	177	13	2	4f88ea4cfcfa8a9af5a14ab6f6be3b2aa015852e
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 RUNX2	1.17e-03	177	13	2	ffc4c675b25ffe8bd3441ce26dd0984fef4b3b88
ToppCell	wk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TENM1 DLX2	1.17e-03	177	13	2	15a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.17e-03	177	13	2	2b675840b7d2bb536c2c600936733bd9e97e7120
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.17e-03	177	13	2	91706bd0d4dda8d98843fb00b898d5aca4d66b64
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.18e-03	178	13	2	c982a73955c9c193bcab21d60d453afcc09cd586
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.18e-03	178	13	2	6ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-6_RORB_HPCA\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 TEX13A	1.18e-03	178	13	2	f2766913de010b718ba3799996d658b8f499adc5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.19e-03	179	13	2	7954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.19e-03	179	13	2	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.19e-03	179	13	2	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TENM1 DLX2	1.19e-03	179	13	2	df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.19e-03	179	13	2	d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TENM1 PAX8	1.21e-03	180	13	2	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.21e-03	180	13	2	8f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TENM1 POLR2A	1.22e-03	181	13	2	12ff56fa2949c8d53360cdf2cacfd326e65b54aa
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.22e-03	181	13	2	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.22e-03	181	13	2	153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.22e-03	181	13	2	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TENM1 PAX8	1.22e-03	181	13	2	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.22e-03	181	13	2	7704f236831cffe4f2a75d4c461eb88b4177e206
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.23e-03	182	13	2	d4cb23b5a974c096a0ce84b47fe351eef44894d7
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.23e-03	182	13	2	a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.23e-03	182	13	2	08aff7112c9dac0ef5540300516a604782b21169
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.25e-03	183	13	2	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TENM1 PAX8	1.25e-03	183	13	2	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.25e-03	183	13	2	d2074b13b4831ec18c81273d9a1ff673c3f6a16d
ToppCell	IPF-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	ARHGAP32 RUNX2	1.25e-03	183	13	2	9b507547e6adf78e46e7f542cd9958224ec5826a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.25e-03	183	13	2	121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCell	droplet-Heart-4Chambers-18m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 DLX2	1.26e-03	184	13	2	d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.26e-03	184	13	2	2ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 DLX2	1.26e-03	184	13	2	6388c47b7f1d8203e3069eba0e74107256dcae51
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.26e-03	184	13	2	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.26e-03	184	13	2	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.27e-03	185	13	2	e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.27e-03	185	13	2	f4ac62009c0ad3346e71b809e17727303c4df153
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TENM1 PAX8	1.29e-03	186	13	2	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.29e-03	186	13	2	948815663c212c4311329d503b5991cbbbff9808
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.29e-03	186	13	2	6379609b7ace80683f5754b16aa77f11b43766ae
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TENM1 PAX8	1.30e-03	187	13	2	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.30e-03	187	13	2	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.30e-03	187	13	2	01393f6d1983eb4a2bcc80252012f77892851679
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.31e-03	188	13	2	72cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TENM1 PAX8	1.31e-03	188	13	2	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.31e-03	188	13	2	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 DLX2	1.31e-03	188	13	2	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.33e-03	189	13	2	78cf414b98bcb19deb934409acddaad1cd51b67f
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 DLX2	1.33e-03	189	13	2	4e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCell	droplet-Heart-HEART-1m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 DLX2	1.33e-03	189	13	2	a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.33e-03	189	13	2	99a13b1b669b0cd36e3096632351d9ade25d1173
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	39ab890104b4264c68a968f920f4ccd84f0bc681
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	0acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	8c9c230a509afaeee50644153974a5642b01a2b8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.34e-03	190	13	2	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.36e-03	191	13	2	782bc7946417549ffd39e5b596db659436fa01ba
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.37e-03	192	13	2	0003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.37e-03	192	13	2	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.37e-03	192	13	2	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.38e-03	193	13	2	53bcd50892c379b2a571751f6eb1062436339fe7
ToppCell	Control-CD8+_T_naive\|Control / Disease condition and Cell class	ZNF609 RUNX2	1.38e-03	193	13	2	627d345baf1940218c61907305705298e473dbab
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ARHGAP32 RUNX2	1.38e-03	193	13	2	826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.38e-03	193	13	2	4979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.38e-03	193	13	2	5581a5ebcd21a2a8062ccfb917f088ec67a10a9c
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 RUNX2	1.38e-03	193	13	2	55eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RUNX2	1.38e-03	193	13	2	c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
Computational	Neighborhood of FANCG	PAX8 POLR2A SEC31A	4.08e-04	167	10	3	MORF_FANCG
Drug	tamoxifen citrate; Up 200; 1uM; ssMCF7; HG-U133A	LRP6 DLX2 ZNF609 RUNX2	3.88e-06	200	13	4	375_UP
Drug	bis(I,I-trifluoroacetoxy)iodobenzene	TENM1 ARHGAP32	1.21e-04	29	13	2	CID000102317
Drug	Ellipticine [519-23-3]; Up 200; 16.2uM; PC3; HT_HG-U133A	DLX2 POLR2A TEX13A	1.27e-04	178	13	3	5779_UP
Drug	Clioquinol [130-26-7]; Up 200; 13uM; HL60; HT_HG-U133A	ARHGAP32 POLR2A RUNX2	1.51e-04	189	13	3	3084_UP
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A	TENM1 PAX8 TEX13A	1.61e-04	193	13	3	7238_UP
Drug	0316684-0000 [391209-55-5]; Up 200; 10uM; PC3; HT_HG-U133A	ARHGAP32 DLX2 ZNF609	1.61e-04	193	13	3	7057_UP
Drug	Rolipram [61413-54-5]; Up 200; 14.6uM; PC3; HT_HG-U133A	TENM1 ZNF609 TEX13A	1.61e-04	193	13	3	6730_UP
Drug	Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A	LRP6 DLX2 POLR2A	1.64e-04	194	13	3	7214_DN
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A	PAX8 ZNF609 POLR2A	1.66e-04	195	13	3	2805_UP
Drug	Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	ZNF609 POLR2A TEX13A	1.69e-04	196	13	3	4281_UP
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A	PAX8 RUNX2 TEX13A	1.69e-04	196	13	3	3817_UP
Drug	Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	PAX8 ZNF609 POLR2A	1.69e-04	196	13	3	3256_UP
Drug	Metrizamide [31112-62-6]; Down 200; 5uM; MCF7; HT_HG-U133A	LRP6 DLX2 ZNF609	1.69e-04	196	13	3	3255_DN
Drug	Ioxaglic acid [59017-64-0]; Down 200; 3.2uM; MCF7; HT_HG-U133A	LRP6 PAX8 ZNF609	1.69e-04	196	13	3	7470_DN
Drug	Clorsulon [60200-06-8]; Down 200; 10.6uM; HL60; HG-U133A	ARHGAP32 ZNF609 POLR2A	1.69e-04	196	13	3	1735_DN
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	LRP6 DLX2 ZNF609	1.71e-04	197	13	3	6867_UP
Drug	Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	PAX8 DLX2 ZNF609	1.71e-04	197	13	3	6482_UP
Drug	Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; PC3; HT_HG-U133A	TENM1 DLX2 TEX13A	1.71e-04	197	13	3	4014_UP
Drug	monastrol; Up 200; 20uM; MCF7; HG-U133A	LRP6 PAX8 RUNX2	1.71e-04	197	13	3	605_UP
Drug	Rifampicin [13292-46-1]; Up 200; 4.8uM; HL60; HT_HG-U133A	DLX2 ZNF609 RUNX2	1.74e-04	198	13	3	2487_UP
Drug	monastrol; Up 200; 100uM; PC3; HG-U133A	LRP6 DLX2 RUNX2	1.74e-04	198	13	3	668_UP
Drug	Azaperone [1649-18-9]; Up 200; 12.2uM; PC3; HT_HG-U133A	TENM1 PAX8 DLX2	1.74e-04	198	13	3	5877_UP
Drug	tetraethylenepentamine pentahydrochloride; Down 200; 100uM; MCF7; HG-U133A	DLX2 ZNF609 POLR2A	1.74e-04	198	13	3	406_DN
Drug	Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A	PAX8 ZNF609 RUNX2	1.74e-04	198	13	3	3790_UP
Drug	Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	DLX2 POLR2A TEX13A	1.76e-04	199	13	3	6771_UP
Drug	Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; PC3; HT_HG-U133A	PAX8 DLX2 ZNF609	1.76e-04	199	13	3	6687_UP
Drug	Dichlororibofuranosylbenzimidazole	POLR2A RUNX2	2.09e-04	38	13	2	ctd:D004004
Drug	AC1NDQQF	LRP6 RUNX2	3.07e-04	46	13	2	CID004630071
Drug	diethylenetriaminepentaacetic acid	LRP6 ARHGAP32	3.93e-04	52	13	2	CID000003053
Drug	vitamin K2	PAX8 RUNX2	6.52e-04	67	13	2	CID000004056
Drug	Mal.4	PAX8 ARHGAP32	7.52e-04	72	13	2	CID000122821
Drug	ethyl methanesulfonate	TENM1 POLR2A	1.77e-03	111	13	2	CID000006113
Drug	(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)	DLX2 YTHDF3 SEC31A	2.17e-03	472	13	3	ctd:C517041
Drug	NSC401575	POLR2A RUNX2	2.39e-03	129	13	2	CID000003165
Drug	Plant Oils	YTHDF1 DLX2 YTHDF3	2.50e-03	496	13	3	ctd:D010938
Drug	m(7)GpppG	RUNX2 TEX13A	2.92e-03	143	13	2	CID000121958
Drug	calcium phosphate	ARHGAP32 RUNX2	3.16e-03	149	13	2	CID000024441
Drug	Niclosamide [50-65-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	DLX2 ZNF609	3.55e-03	158	13	2	4136_UP
Drug	Proscillaridin A [466-06-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A	LRP6 DLX2	3.73e-03	162	13	2	7340_UP
Drug	Helveticoside [630-64-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A	DLX2 ZNF609	3.96e-03	167	13	2	6047_UP
Drug	Lycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A	DLX2 ZNF609	4.00e-03	168	13	2	4365_UP
Drug	Digoxin [20830-75-5]; Up 200; 5.2uM; PC3; HT_HG-U133A	DLX2 ZNF609	4.05e-03	169	13	2	6724_UP
Drug	titanium	ARHGAP32 RUNX2	4.10e-03	170	13	2	CID000023963
Drug	retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	PAX8 ZNF609	4.14e-03	171	13	2	991_UP
Drug	hydroxyapatite	ARHGAP32 RUNX2	4.14e-03	171	13	2	CID000014781
Drug	dimethyloxalylglycine; Up 200; 1000uM; PC3; HG-U133A	DLX2 ZNF609	4.19e-03	172	13	2	584_UP
Drug	Digoxigenin [1672-46-4]; Up 200; 10.2uM; HL60; HT_HG-U133A	PAX8 DLX2	4.43e-03	177	13	2	3060_UP
Drug	Camptothecine (S,+) [7689-03-4]; Up 200; 11.4uM; PC3; HT_HG-U133A	DLX2 RUNX2	4.53e-03	179	13	2	4541_UP
Drug	Digitoxigenin [143-62-4]; Up 200; 10.6uM; PC3; HT_HG-U133A	DLX2 ZNF609	4.53e-03	179	13	2	4217_UP
Drug	Miconazole [22916-47-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A	LRP6 DLX2	4.58e-03	180	13	2	1477_UP
Disease	congenital hypothyroidism (implicated_via_orthology)	PAX8 RUNX2	1.38e-05	14	12	2	DOID:0050328 (implicated_via_orthology)
Disease	disease of metabolism (implicated_via_orthology)	YTHDF1 YTHDF3	3.17e-05	21	12	2	DOID:0014667 (implicated_via_orthology)
Disease	Craniofacial Abnormalities	DLX2 RUNX2	1.77e-03	156	12	2	C0376634
Disease	anthropometric measurement	POLR2A RUNX2	2.05e-03	168	12	2	EFO_0004302

Protein segments in the cluster

Peptide	Gene	Start	Entry
YTSYAPYGTSSSPAN	DLX2	116	Q07687
SSPYYYSSTSRPSAP	PAX8	426	Q06710
SNSPSTHRSYSYRPY	LRP6	1506	O75581
SPYSSSSSSYYSPDG	ARHGAP32	1651	A7KAX9
PFQTSSTPYLYYGTS	RUNX2	436	Q13950
YTSPYSPNASSPYSS	SLAIN2	196	Q9P270
GYYRNIYTPPDSSTS	TENM1	1931	Q9UKZ4
TQSSAYSSSYGYPPS	YTHDF3	146	Q7Z739
YSPTSPSYSPTSPSY	POLR2A	1636	P24928
YSPTSPSYSPTSPSY	POLR2A	1671	P24928
YSPTSPSYSPTSPSY	POLR2A	1706	P24928
YSPTSPNYSPTSPNY	POLR2A	1741	P24928
YTPTSPNYSPTSPSY	POLR2A	1776	P24928
SYSPTSPSYSPSSPR	POLR2A	1796	P24928
YTPQSPTYTPSSPSY	POLR2A	1811	P24928
SSPSYSPSSPSYSPA	POLR2A	1821	P24928
ESYYSPSYAQSSPGA	ZNF609	896	O15014
LPASYSYSYSSPFSS	TEX13A	296	Q9BXU3
AYPNTPYISSASSYT	SEC31A	906	O94979
QTQSSAYGSSYTYPP	YTHDF1	141	Q9BYJ9