Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

HCN4 HCN1 SLC6A15 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1

4.44e-071711109GO:0015081
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

HCN4 TRPM7 HCN1 PKD1L1 SLC6A15 PKD1L3 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1 TRPV3

1.71e-0646511013GO:0046873
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC12A1 SLC12A3 SLC18A1 SLC22A3

1.96e-06171104GO:0015378
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC12A1 SLC12A3 SLC18A1 SLC22A3

3.17e-06191104GO:0015373
GeneOntologyMolecularFunctionolfactory receptor activity

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

4.58e-0643111012GO:0004984
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A15 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SLC28A1

5.65e-06811106GO:0015370
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC12A1 SLC12A3 SLC18A1 SLC22A3

7.12e-06231104GO:0015377
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC12A1 SLC12A3 SLC18A1 SLC22A3

1.19e-05261104GO:0015296
GeneOntologyMolecularFunctionDEAD/H-box RNA helicase binding

SMAD1 SMAD3 SMAD5

1.33e-0591103GO:0017151
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ANO4 ABCC4 HCN4 TRPM7 HCN1 PKD1L1 SLC6A15 PKD1L3 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1 TRPV3

1.75e-0575811015GO:0015318
GeneOntologyMolecularFunctionsymporter activity

SLC6A17 SLC6A15 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SLC28A1

1.96e-051501107GO:0015293
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PTGER3 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

2.68e-0588411016GO:0004930
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ANO4 HCN4 TRPM7 HCN1 PKD1L1 SLC6A15 PKD1L3 TMC3 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1 TRPV3

2.96e-0579311015GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

HCN4 TRPM7 HCN1 PKD1L1 SLC6A15 PKD1L3 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1 TRPV3

4.14e-0562711013GO:0022890
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A15 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SLC28A1

5.10e-051191106GO:0015294
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

HCN4 TRPM7 HCN1 PKD1L1 SLC6A15 PKD1L3 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1 TRPV3

7.42e-0566411013GO:0008324
GeneOntologyMolecularFunctiontransporter activity

ANO4 ABCC4 HCN4 TRPM7 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 TMC3 GJD4 CLPTM1L SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1 TRPV3

7.42e-05128911019GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

ANO4 ABCC4 HCN4 TRPM7 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 TMC3 GJD4 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SCN10A SLC28A1 TRPV3

7.62e-05118011018GO:0022857
GeneOntologyMolecularFunctionsodium:potassium:chloride symporter activity

SLC12A1 SLC12A3

8.99e-0531102GO:0008511
GeneOntologyMolecularFunctionpotassium:sodium symporter activity

SLC12A1 SLC12A3

8.99e-0531102GO:0009674
GeneOntologyMolecularFunctionI-SMAD binding

SMAD1 SMAD3 SMAD5

1.05e-04171103GO:0070411
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PKD1L3 PTGER3 OR4P4 OR10AG1 PTPRK OR1K1 FGFR2 OR4D5 OR4C5

1.40e-04135311019GO:0004888
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ANO4 ABCC4 SLC12A1 SLC12A3 SLC18A1 SLC22A3

3.71e-041711106GO:0015103
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

HCN4 HCN1 SCN10A

3.86e-04261103GO:0005248
GeneOntologyMolecularFunctionbeta-catenin binding

PTPRK CSNK2A1 MED12L MED12 SMAD3

5.34e-041201105GO:0008013
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

ANO4 SLC12A1 SLC12A3 SLC18A1 SLC22A3

6.43e-041251105GO:0015108
GeneOntologyMolecularFunctionchannel activity

ANO4 HCN4 TRPM7 HCN1 PKD1L1 PKD1L3 TMC3 GJD4 SCN10A TRPV3

6.48e-0452511010GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ANO4 HCN4 TRPM7 HCN1 PKD1L1 PKD1L3 TMC3 GJD4 SCN10A TRPV3

6.57e-0452611010GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ANO4 HCN4 TRPM7 HCN1 PKD1L1 PKD1L3 TMC3 SCN10A TRPV3

9.91e-044591109GO:0005216
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A1 SLC12A3

1.06e-0391102GO:0015379
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A17 SLC6A15 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SLC28A1

1.27e-032961107GO:0015291
GeneOntologyMolecularFunctionintracellularly cAMP-activated cation channel activity

HCN4 HCN1

1.31e-03101102GO:0005222
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

ANO4 SLC12A1 SLC12A3 SLC18A1 SLC22A3

1.50e-031511105GO:0008509
GeneOntologyMolecularFunctionDNA endonuclease activity

DICER1 ZRANB3 GEN1

1.83e-03441103GO:0004520
GeneOntologyMolecularFunctionmonoamine transmembrane transporter activity

SLC18A1 SLC22A3

1.91e-03121102GO:0008504
GeneOntologyMolecularFunctionN-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity

B3GALT2 B3GALT1

1.91e-03121102GO:0008499
GeneOntologyMolecularFunctionco-SMAD binding

SMAD1 SMAD3

1.91e-03121102GO:0070410
GeneOntologyMolecularFunctionintracellularly cyclic nucleotide-activated monoatomic cation channel activity

HCN4 HCN1

2.25e-03131102GO:0005221
GeneOntologyMolecularFunctioncyclic nucleotide-activated monoatomic ion channel activity

HCN4 HCN1

2.25e-03131102GO:0043855
GeneOntologyMolecularFunctionendodeoxyribonuclease activity, producing 5'-phosphomonoesters

DICER1 GEN1

2.62e-03141102GO:0016888
GeneOntologyMolecularFunctionmonoatomic cation channel activity

HCN4 TRPM7 HCN1 PKD1L1 PKD1L3 SCN10A TRPV3

2.92e-033431107GO:0005261
GeneOntologyMolecularFunctionsodium channel activity

HCN4 HCN1 SCN10A

2.95e-03521103GO:0005272
GeneOntologyMolecularFunctionbeta-1,3-galactosyltransferase activity

B3GALT2 B3GALT1

3.01e-03151102GO:0048531
GeneOntologyMolecularFunctionMAP kinase activity

MAPK10 MAPK13

3.43e-03161102GO:0004707
GeneOntologyMolecularFunction1-phosphatidylinositol binding

SNX9 WDFY1

3.87e-03171102GO:0005545
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC4 SLC6A17 SLC6A15 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SLC28A1

4.90e-034771108GO:0022804
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

IPO13 SMAD3

5.36e-03201102GO:0035259
GeneOntologyBiologicalProcessdetection of stimulus

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 OR13F1 PKD1L1 OR2W1 OR2T2 PKD1L3 OR4P4 OR10AG1 SCN10A REG3A OR1K1 OR4D5 OR4C5

3.11e-0772211117GO:0051606
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ANO4 ABCC4 MYO5A HCN4 TRPM7 PMPCB GPR39 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 PTGER3 TMC3 SLC12A1 SLC12A3 SLC18A1 GNB5 SCN10A TRPV3 OGA

4.50e-07111511121GO:0034220
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 PKD1L3 OR4P4 OR10AG1 SCN10A OR1K1 OR4D5 OR4C5

5.35e-0758211115GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 PKD1L3 OR4P4 OR10AG1 REG3A OR1K1 OR4D5 OR4C5

8.64e-0752411114GO:0009593
GeneOntologyBiologicalProcessmonoatomic ion transport

ANO4 ABCC4 HTR7 MYO5A HCN4 TRPM7 PMPCB GPR39 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 PTGER3 TMC3 SLC12A1 SLC12A3 SLC18A1 SLC22A3 GNB5 SCN10A TRPV3 OGA

9.17e-07137411123GO:0006811
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ANO4 MYO5A HCN4 TRPM7 PMPCB GPR39 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 PTGER3 SLC12A1 SLC12A3 SLC18A1 GNB5 SCN10A TRPV3 OGA

1.94e-06101711119GO:0098660
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

MYO5A HCN4 TRPM7 PMPCB GPR39 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 PTGER3 SLC12A1 SLC12A3 SLC18A1 GNB5 SCN10A TRPV3 OGA

2.02e-0692211118GO:0098662
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 PKD1L3 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

2.11e-0648511113GO:0050907
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

MYO5A HCN4 TRPM7 PMPCB GPR39 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 PTGER3 SLC12A1 SLC12A3 SLC18A1 GNB5 SCN10A TRPV3 OGA

2.74e-0694211118GO:0098655
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

3.72e-0643211112GO:0050911
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 PKD1L3 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

7.79e-0654711113GO:0007606
GeneOntologyBiologicalProcesssensory perception of smell

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

7.84e-0646511112GO:0007608
GeneOntologyBiologicalProcessregulation of membrane depolarization

ADCY10 HCN4 HCN1 SCN10A OGA

1.93e-05611115GO:0003254
GeneOntologyBiologicalProcessmetal ion transport

MYO5A HCN4 TRPM7 PMPCB GPR39 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 PTGER3 SLC12A1 SLC12A3 GNB5 SCN10A TRPV3 OGA

2.44e-05100011117GO:0030001
GeneOntologyBiologicalProcessmonoatomic cation transport

MYO5A HCN4 TRPM7 PMPCB GPR39 HCN1 SLC6A17 PKD1L1 SLC6A15 PKD1L3 PTGER3 SLC12A1 SLC12A3 SLC18A1 GNB5 SCN10A TRPV3 OGA

4.41e-05115711118GO:0006812
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

ADCY10 OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PTGER3 GPR180 OR4P4 OR10AG1 GNB5 OR1K1 OR4D5 PSAPL1 OR4C5

5.00e-05139511120GO:0007186
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

MYO5A TRPM7 PMPCB GPR39 PKD1L1 PKD1L3 PTGER3 GNB5 TRPV3 OGA

5.14e-0539211110GO:0070588
GeneOntologyBiologicalProcesspurine-containing compound transmembrane transport

ADCY10 ABCC4 SLC22A3 SLC28A1

6.25e-05401114GO:0072530
GeneOntologyBiologicalProcesssodium ion transmembrane transport

HCN4 HCN1 SLC6A17 SLC6A15 SLC12A1 SLC12A3 SCN10A

1.34e-042081117GO:0035725
GeneOntologyBiologicalProcessembryonic cranial skeleton morphogenesis

CHST11 FGFR2 MED12 SMAD3

1.76e-04521114GO:0048701
GeneOntologyBiologicalProcessactin filament-based movement

ADCY10 MYO5A HCN4 PTGER3 MYO5C SCN10A

1.80e-041531116GO:0030048
GeneOntologyBiologicalProcesssensory perception

OR4K2 OR2L3 HTR7 MYO5A OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 PKD1L3 OR4P4 OR10AG1 SCN10A OR1K1 OR4D5 OR4C5

1.97e-04107211116GO:0007600
GeneOntologyBiologicalProcessregulation of keratinocyte proliferation

PTPRK REG3A FGFR2 IFT80

2.35e-04561114GO:0010837
GeneOntologyBiologicalProcessnegative regulation of gastric acid secretion

GPR39 PTGER3

2.84e-0451112GO:0060455
GeneOntologyBiologicalProcessplasma membrane phospholipid scrambling

ANO4 CLPTM1L XKR5

3.60e-04261113GO:0017121
GeneOntologyBiologicalProcessmonoamine transport

HTR7 MYO5A PTGER3 SLC18A1 SLC22A3

4.11e-041161115GO:0015844
GeneOntologyBiologicalProcessgalactosylceramide biosynthetic process

B3GALT2 B3GALT1

4.24e-0461112GO:0006682
GeneOntologyBiologicalProcessosteoblast fate commitment

SMAD1 SMAD5

4.24e-0461112GO:0002051
GeneOntologyBiologicalProcessgalactolipid biosynthetic process

B3GALT2 B3GALT1

4.24e-0461112GO:0019375
GeneOntologyBiologicalProcesscalcium ion transport

MYO5A TRPM7 PMPCB GPR39 PKD1L1 PKD1L3 PTGER3 GNB5 TRPV3 OGA

4.26e-0450911110GO:0006816
GeneOntologyBiologicalProcessmembrane depolarization

ADCY10 HCN4 HCN1 SCN10A OGA

4.99e-041211115GO:0051899
GeneOntologyBiologicalProcessnegative regulation of keratinocyte proliferation

PTPRK FGFR2 IFT80

5.01e-04291113GO:0010839
GeneOntologyBiologicalProcesskeratinocyte proliferation

PTPRK REG3A FGFR2 IFT80

5.54e-04701114GO:0043616
GeneOntologyBiologicalProcessprotein processing involved in protein targeting to mitochondrion

PMPCB MIPEP

5.92e-0471112GO:0006627
GeneOntologyCellularComponentheteromeric SMAD protein complex

SMAD1 SMAD3 SMAD5

7.79e-0681103GO:0071144
GeneOntologyCellularComponentSMAD protein complex

SMAD1 SMAD3 SMAD5

1.66e-05101103GO:0071141
GeneOntologyCellularComponentHCN channel complex

HCN4 HCN1

1.64e-0441102GO:0098855
GeneOntologyCellularComponentpresynaptic endosome

SNX4 VAC14

5.66e-0471102GO:0098830
Domain7tm_1

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PTGER3 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

1.93e-0667710916PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PTGER3 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

2.24e-0668510916PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PTGER3 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

2.51e-0669110916PS50262
DomainGPCR_Rhodpsn

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PTGER3 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

2.56e-0669210916IPR000276
DomainOlfact_rcpt

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

3.18e-0639310912IPR000725
DomainGPCR_Rhodpsn_7TM

OR4K2 OR2L3 HTR7 OR4C16 OR2T35 GPR39 OR13F1 GPR173 OR2W1 OR2T2 PTGER3 OR4P4 OR10AG1 OR1K1 OR4D5

7.99e-0667010915IPR017452
DomainDwarfin

SMAD1 SMAD3 SMAD5

1.06e-0581093IPR013790
DomainDWB

SMAD1 SMAD3 SMAD5

1.06e-0581093SM00524
DomainMH2

SMAD1 SMAD3 SMAD5

1.06e-0581093PS51076
DomainMH1

SMAD1 SMAD3 SMAD5

1.06e-0581093PS51075
Domain-

SMAD1 SMAD3 SMAD5

1.06e-05810933.90.520.10
DomainMAD_homology_MH1

SMAD1 SMAD3 SMAD5

1.06e-0581093IPR013019
DomainMH2

SMAD1 SMAD3 SMAD5

1.06e-0581093PF03166
DomainSMAD_dom_Dwarfin-type

SMAD1 SMAD3 SMAD5

1.06e-0581093IPR001132
DomainMediator_Med12

MED12L MED12

3.37e-0521092IPR019035
DomainMed12

MED12L MED12

3.37e-0521092PF09497
DomainMediator_Med12_LCEWAV

MED12L MED12

3.37e-0521092IPR021990
DomainMediator_Med12_catenin-bd

MED12L MED12

3.37e-0521092IPR021989
DomainMed12-PQL

MED12L MED12

3.37e-0521092PF12144
DomainMed12-LCEWAV

MED12L MED12

3.37e-0521092PF12145
DomainMed12

MED12L MED12

3.37e-0521092SM01281
DomainMAD_homology1_Dwarfin-type

SMAD1 SMAD3 SMAD5

4.09e-05121093IPR003619
DomainDWA

SMAD1 SMAD3 SMAD5

4.09e-05121093SM00523
DomainMH1

SMAD1 SMAD3 SMAD5

4.09e-05121093PF03165
DomainAA_permease_N

SLC12A1 SLC12A3

1.01e-0431092IPR013612
DomainAA_permease_N

SLC12A1 SLC12A3

1.01e-0431092PF08403
DomainSMAD_dom-like

SMAD1 SMAD3 SMAD5

1.02e-04161093IPR017855
Domain-

SMAD1 SMAD3 SMAD5

1.02e-041610932.60.200.10
DomainIon_trans_N

HCN4 HCN1

2.01e-0441092PF08412
DomainIon_trans_N

HCN4 HCN1

2.01e-0441092IPR013621
DomainNa/ntran_symport_orphan

SLC6A17 SLC6A15

3.34e-0451092IPR002438
DomainMAPK_JNK

MAPK10 MAPK13

3.34e-0451092IPR008351
DomainMyosin_S1_N

MYO5A MYO5C

3.34e-0451092IPR008989
DomainWD40_repeat_CS

TRAF7 EED TBL3 WDR53 GNB5 WDFY1

4.02e-041641096IPR019775
DomainDIL

MYO5A MYO5C

4.99e-0461092PF01843
DomainDilute_dom

MYO5A MYO5C

4.99e-0461092IPR002710
DomainDILUTE

MYO5A MYO5C

4.99e-0461092PS51126
DomainDIL

MYO5A MYO5C

4.99e-0461092SM01132
DomainIon_trans_dom

HCN4 TRPM7 HCN1 SCN10A TRPV3

5.47e-041141095IPR005821
DomainIon_trans

HCN4 TRPM7 HCN1 SCN10A TRPV3

5.47e-041141095PF00520
DomainSLC12A_fam

SLC12A1 SLC12A3

6.95e-0471092IPR004842
DomainWD40

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

8.15e-042591097PF00400
DomainSLC12_C

SLC12A1 SLC12A3

9.24e-0481092IPR018491
DomainSLC12

SLC12A1 SLC12A3

9.24e-0481092PF03522
DomainWD40

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

9.94e-042681097SM00320
DomainWD40_repeat

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

1.08e-032721097IPR001680
DomainPAZ

PIWIL4 DICER1

1.18e-0391092PS50821
DomainPAZ

PIWIL4 DICER1

1.18e-0391092SM00949
DomainPAZ_dom

PIWIL4 DICER1

1.18e-0391092IPR003100
DomainPAZ

PIWIL4 DICER1

1.18e-0391092PF02170
DomainWD_REPEATS_1

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

1.23e-032781097PS00678
DomainWD_REPEATS_2

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

1.25e-032791097PS50082
DomainWD_REPEATS_REGION

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

1.25e-032791097PS50294
DomainG-protein_beta_WD-40_rep

TRAF7 TBL3 GNB5 WDFY1

1.55e-03851094IPR020472
DomainWD40_repeat_dom

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

1.79e-032971097IPR017986
DomainPKD_channel

PKD1L1 PKD1L3

1.79e-03111092PF08016
DomainPKD1_2_channel

PKD1L1 PKD1L3

1.79e-03111092IPR013122
DomainMAP_kinase_CS

MAPK10 MAPK13

2.14e-03121092IPR003527
DomainMAPK

MAPK10 MAPK13

2.14e-03121092PS01351
DomainK_chnl_volt-dep_EAG/ELK/ERG

HCN4 HCN1

2.93e-03141092IPR003938
Domain-

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

3.39e-0333310972.130.10.10
DomainSMAD_FHA_domain

SMAD1 SMAD3 SMAD5

3.47e-03521093IPR008984
DomainWD40/YVTN_repeat-like_dom

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

3.51e-033351097IPR015943
DomainARM-type_fold

DOCK8 NOC2L TRRAP VAC14 THADA PI4KA IPO13

3.74e-033391097IPR016024
DomainGlyco_trans_31

B3GALT2 B3GALT1

3.84e-03161092IPR002659
DomaincNMP-bd_CS

HCN4 HCN1

3.84e-03161092IPR018488
DomainGalactosyl_T

B3GALT2 B3GALT1

3.84e-03161092PF01762
Domain-

TRRAP PI4KA

3.84e-031610921.10.1070.11
DomainPI3Kc

TRRAP PI4KA

3.84e-03161092SM00146
DomainLH2

PKD1L1 PKD1L3

4.86e-03181092SM00308
DomainPI3/4_kinase_cat_dom

TRRAP PI4KA

4.86e-03181092IPR000403
DomainPI3_PI4_kinase

TRRAP PI4KA

4.86e-03181092PF00454
DomainPI3_4_KINASE_3

TRRAP PI4KA

4.86e-03181092PS50290
DomainNA_NEUROTRAN_SYMP_2

SLC6A17 SLC6A15

4.86e-03181092PS00754
DomainPI3_4_KINASE_1

TRRAP PI4KA

4.86e-03181092PS00915
DomainPI3_4_KINASE_2

TRRAP PI4KA

4.86e-03181092PS00916
DomainGUANYLATE_CYCLASE_1

ADCY10 GUCY1B2

5.41e-03191092PS00452
DomainSNF

SLC6A17 SLC6A15

5.41e-03191092PF00209
DomainGuanylate_cyc

ADCY10 GUCY1B2

5.41e-03191092PF00211
DomainNA_NEUROTRAN_SYMP_1

SLC6A17 SLC6A15

5.41e-03191092PS00610
DomainGUANYLATE_CYCLASE_2

ADCY10 GUCY1B2

5.41e-03191092PS50125
DomainNA_NEUROTRAN_SYMP_3

SLC6A17 SLC6A15

5.41e-03191092PS50267
DomainA/G_cyclase

ADCY10 GUCY1B2

5.41e-03191092IPR001054
DomainCYCc

ADCY10 GUCY1B2

5.41e-03191092SM00044
DomainNa/ntran_symport

SLC6A17 SLC6A15

5.41e-03191092IPR000175
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR2T2 OR4P4 OR10AG1 OR1K1 OR4D5 OR4C5

1.30e-054179012M4072
Pubmed

EP3 activation facilitates bladder excitability via HCN channels on ICCs.

HCN4 HCN1 PTGER3

3.43e-083114328131828
Pubmed

Expression of the BMP receptor Alk3 in the second heart field is essential for development of the dorsal mesenchymal protrusion and atrioventricular septation.

VCAN SMAD1 SMAD3 SMAD5

1.07e-0714114423584254
Pubmed

Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus.

SMAD1 SMAD3 SMAD5

1.37e-074114319247629
Pubmed

Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney.

SLC12A1 SLC12A3 SMAD1 SMAD5

1.93e-0716114435877077
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR4P4 OR10AG1 OR4D5 OR4C5

1.93e-073401141011875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR4P4 OR10AG1 OR4D5 OR4C5

1.93e-073401141011802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR4P4 OR10AG1 OR4D5 OR4C5

2.10e-073431141032295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR4K2 OR2L3 OR4C16 OR2T35 OR13F1 OR2W1 OR4P4 OR10AG1 OR4D5 OR4C5

2.27e-073461141014611657
Pubmed

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

SMAD1 SMAD3 SMAD5

3.41e-075114315647271
Pubmed

The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter.

SMAD1 SMAD3 SMAD5

3.41e-075114317251190
Pubmed

Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors.

SMAD1 SMAD3 SMAD5

3.41e-075114319819941
Pubmed

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

SMAD1 SMAD3 SMAD5

3.41e-075114325141865
Pubmed

Mad-related genes in the human.

SMAD1 SMAD3 SMAD5

3.41e-07511438673135
Pubmed

Fgf9 signaling regulates small intestinal elongation and mesenchymal development.

FGFR2 SMAD1 SMAD3 SMAD5

5.09e-0720114418653563
Pubmed

RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1.

FGFR2 SMAD1 SMAD3 SMAD5

5.09e-0720114432662771
Pubmed

Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity.

SMAD1 SMAD3 SMAD5

6.81e-076114318393632
Pubmed

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes.

SMAD1 SMAD3 SMAD5

6.81e-076114310400677
Pubmed

Smad7 is required for the development and function of the heart.

SMAD1 SMAD3 SMAD5

6.81e-076114318952608
Pubmed

Immunohistochemical expression of Smads 1-6 in the 15-day gestation mouse embryo: signaling by BMPs and TGF-betas.

SMAD1 SMAD3 SMAD5

6.81e-076114311169847
Pubmed

Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney.

SMAD1 SMAD3 SMAD5

6.81e-076114311850197
Pubmed

Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.

SMAD1 SMAD3 SMAD5

1.19e-067114315009097
Pubmed

Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski.

SMAD1 SMAD3 SMAD5

1.19e-067114314699069
Pubmed

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.

SMAD1 SMAD3 SMAD5

1.19e-067114310376010
Pubmed

Negative regulation of BMP/Smad signaling by Tob in osteoblasts.

SMAD1 SMAD3 SMAD5

1.19e-067114311163184
Pubmed

Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.

SMAD1 SMAD3 SMAD5

1.19e-067114315150273
Pubmed

Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.

SMAD1 SMAD3 SMAD5

1.19e-067114312370310
Pubmed

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.

SMAD1 SMAD3 SMAD5

1.19e-067114314580334
Pubmed

Pkd1 is required for male reproductive tract development.

SMAD1 SMAD3 SMAD5

1.19e-067114323933588
Pubmed

A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension.

SMAD1 SMAD3 SMAD5

1.90e-068114319211612
Pubmed

Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

SMAD1 SMAD3 SMAD5

1.90e-068114310647776
Pubmed

Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin.

SMAD1 SMAD3 SMAD5

1.90e-068114312714599
Pubmed

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter.

SMAD1 SMAD3 SMAD5

1.90e-068114310531362
Pubmed

Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.

SMAD1 SMAD3 SMAD5

1.90e-068114323804438
Pubmed

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

SMAD1 SMAD3 SMAD5

1.90e-068114311278251
Pubmed

TGF-beta signaling by Smad proteins.

SMAD1 SMAD3 SMAD5

1.90e-068114310708949
Pubmed

GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.

SMAD1 SMAD3 SMAD5

2.84e-069114324932701
Pubmed

Holding their own: the noncanonical roles of Smad proteins.

SMAD1 SMAD3 SMAD5

2.84e-069114319018011
Pubmed

TGF-beta signal transduction.

SMAD1 SMAD3 SMAD5

2.84e-06911439759503
Pubmed

Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.

SMAD1 SMAD3 SMAD5

2.84e-069114330134160
Pubmed

Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations.

SMAD1 SMAD3 SMAD5

2.84e-069114324816837
Pubmed

Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality.

HCN4 SMAD1 SMAD5

2.84e-069114325428115
Pubmed

Dullard/Ctdnep1 regulates endochondral ossification via suppression of TGF-β signaling.

SMAD1 SMAD3 SMAD5

2.84e-069114325155999
Pubmed

The Smad pathway.

SMAD1 SMAD3 SMAD5

2.84e-069114310708948
Pubmed

The non-canonical BMP and Wnt/β-catenin signaling pathways orchestrate early tooth development.

FGFR2 SMAD1 SMAD3 SMAD5

3.67e-0632114425428587
Pubmed

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation.

VCAN SMAD1 SMAD5

4.05e-061011439076683
Pubmed

TGF-β signaling inhibits canonical BMP signaling pathway during palate development.

SMAD1 SMAD3 SMAD5

4.05e-0610114329247325
Pubmed

Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.

SMAD1 SMAD3 SMAD5

4.05e-0610114323620745
Pubmed

The crucial role of the TRPM7 kinase domain in the early stage of amelogenesis.

TRPM7 SMAD1 SMAD5

4.05e-0610114329273814
Pubmed

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).

SMAD1 SMAD3 SMAD5

4.05e-0610114315221015
Pubmed

Protein Arginine Methyltransferase PRMT1 Is Essential for Palatogenesis.

SMAD1 SMAD3 SMAD5

4.05e-0610114329986157
Pubmed

The secondary heart field is a new site of calcineurin/Nfatc1 signaling for semilunar valve development.

VCAN SMAD1 SMAD5

4.05e-0610114322300732
Pubmed

Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice.

SMAD1 SMAD3 SMAD5

4.05e-0610114312543979
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPM7 PKD1L1 PKD1L3 TRPV3

4.16e-0633114419834762
Pubmed

Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis.

VCAN FGFR2 SMAD1 SMAD5

5.30e-0635114418676816
Pubmed

Mechanical feedback defines organizing centers to drive digit emergence.

SMAD1 SMAD3 SMAD5

5.55e-0611114335413235
Pubmed

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.

SMAD1 SMAD3 SMAD5

5.55e-0611114327741240
Pubmed

Downregulation of bone morphogenetic protein receptor axis during HIV-1 and cocaine-mediated pulmonary smooth muscle hyperplasia: implications for HIV-related pulmonary arterial hypertension.

SMAD1 SMAD3 SMAD5

5.55e-0611114324008158
Pubmed

Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.

HCN4 VCAN SMAD1 SMAD5

5.95e-0636114429891551
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EED MYO5A ACADVL TRPM7 PMPCB NOC2L TMEM126B SLC6A15 DICER1 TBL3 MPRIP CLPTM1L THADA PI4KA RAB3GAP2 IFT80 OGA

7.13e-0614871141733957083
Pubmed

BMPR-II is dispensable for formation of the limb skeleton.

SMAD1 SMAD3 SMAD5

7.38e-0612114321538804
Pubmed

Smad expression during kidney development.

SMAD1 SMAD3 SMAD5

7.38e-0612114314656760
Pubmed

Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.

SMAD1 SMAD3 SMAD5

7.38e-0612114317460146
Pubmed

Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.

SMAD1 SMAD3 SMAD5

9.58e-0613114316959237
Pubmed

Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse.

SMAD1 SMAD3 SMAD5

9.58e-0613114318329379
Pubmed

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.

SMAD1 SMAD3 SMAD5

9.58e-0613114319914168
Pubmed

Endoglin is required for myogenic differentiation potential of neural crest stem cells.

SMAD1 SMAD3 SMAD5

9.58e-0613114317628518
Pubmed

The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III.

CSNK2A1 SNAPC4

1.07e-052114217670747
Pubmed

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells.

SMAD1 SMAD5

1.07e-052114226711875
Pubmed

Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels.

HCN4 HCN1

1.07e-052114217548059
Pubmed

The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signalling.

SMAD1 SMAD5

1.07e-052114211451566
Pubmed

Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport.

SLC6A17 SLC6A15

1.07e-052114219147495
Pubmed

Urinary exosomes in the diagnosis of Gitelman and Bartter syndromes.

SLC12A1 SLC12A3

1.07e-052114225422309
Pubmed

BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development.

SMAD1 SMAD5

1.07e-052114232210087
Pubmed

Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity.

HCN4 TRPM7

1.07e-052114223878236
Pubmed

Activin A promotes hyaluronan production and upregulates versican expression in human granulosa cells†.

VCAN SMAD3

1.07e-052114235403677
Pubmed

BMP receptor-integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow.

SMAD1 SMAD5

1.07e-052114223387849
Pubmed

Human myosin-Vc is a novel class V myosin expressed in epithelial cells.

MYO5A MYO5C

1.07e-052114211870218
Pubmed

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.

SMAD1 SMAD5

1.07e-05211428799132
Pubmed

Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.

SMAD1 SMAD3

1.07e-052114220147459
Pubmed

Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer.

MYO5A GNB5

1.07e-052114237957716
Pubmed

BMP signaling dynamics in embryonic orofacial tissue.

SMAD1 SMAD5

1.07e-052114218446813
Pubmed

A Myosin Va mutant mouse with disruptions in glutamate synaptic development and mature plasticity in visual cortex.

MYO5A GNB5

1.07e-052114223658184
Pubmed

Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization.

SMAD1 SMAD5

1.07e-052114221723296
Pubmed

Regulation of the levels of Smad1 and Smad5 in MC3T3-E1 cells by Icariine in vitro.

SMAD1 SMAD5

1.07e-052114224297369
Pubmed

Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells.

HCN4 HCN1

1.07e-052114221456027
Pubmed

Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.

HCN4 HCN1

1.07e-052114211675786
Pubmed

Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.

DICER1 SCN10A

1.07e-052114220702715
Pubmed

Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase catalyzing the formation of type 1 chains.

B3GALT2 B3GALT1

1.07e-05211429417100
Pubmed

Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal Synapses.

MYO5A GNB5

1.07e-052114233229412
Pubmed

Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels.

TRPM7 PTGER3

1.07e-052114230338939
Pubmed

Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells.

HCN4 HCN1

1.07e-052114219135060
Pubmed

Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin.

MYO5A MYO5C

1.07e-052114226912658
Pubmed

From Fish Physiology to Human Disease: The Discovery of the NCC, NKCC2, and the Cation-Coupled Chloride Cotransporters.

SLC12A1 SLC12A3

1.07e-052114237968800
Pubmed

Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney.

SLC12A1 SLC12A3

1.07e-05211428021284
Pubmed

Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development.

SMAD1 SMAD3 SMAD5

1.22e-0514114317670744
Pubmed

The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.

SMAD1 SMAD3 SMAD5

1.22e-0514114338951500
Pubmed

Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development.

FGFR2 SMAD1 SMAD5

1.22e-0514114317693062
Pubmed

Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture.

SMAD1 SMAD3 SMAD5

1.22e-0514114333248111
Pubmed

The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord.

SMAD1 SMAD3 SMAD5

1.22e-0514114316790475
Pubmed

The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary function as a pacemaker during cardiogenesis.

HCN4 SMAD1 SMAD5

1.22e-0514114325488669
Cytoband15q21

MYO5A TRPM7 MYO5C

2.43e-0611114315q21
CytobandEnsembl 112 genes in cytogenetic band chr15q21

MYO5A TRPM7 MYO5C SLC12A1 GNB5

8.41e-051771145chr15q21
Cytoband17p13.1

ACADVL CTC1 DNAH2 KRBA2

2.23e-04118114417p13.1
Cytoband10q26

DPYSL4 FGFR2

1.49e-0323114210q26
CytobandEnsembl 112 genes in cytogenetic band chr17p13

ACADVL CTC1 DNAH2 KRBA2 TRPV3

1.77e-033461145chr17p13
Cytoband1q44

OR2L3 OR2T35 OR2T2

2.65e-0311011431q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2L3 OR2T35 OR2T2

4.06e-031281143chr1q44
CytobandEnsembl 112 genes in cytogenetic band chr11q11

OR4C16 OR4P4

4.48e-03401142chr11q11
GeneFamilySMAD family

SMAD1 SMAD3 SMAD5

5.33e-068843750
GeneFamilyMyosins, class V

MYO5A MYO5C

6.38e-0538421100
GeneFamilyWD repeat domain containing

TRAF7 EED TBL3 WDR53 GNB5 IFT80 WDFY1

2.17e-04262847362
GeneFamilyOlfactory receptors, family 4

OR4K2 OR4C16 OR4P4 OR4D5 OR4C5

3.36e-04129845151
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PKD1L3 VCAN REG3A

9.08e-04418431298
GeneFamilyCyclic nucleotide gated channels

HCN4 HCN1

9.37e-0410842250
GeneFamilySorting nexins|PX-BAR domain containing

SNX4 SNX9

1.37e-03128421290
GeneFamilyMitogen-activated protein kinases

MAPK10 MAPK13

1.61e-0313842651
GeneFamilyOlfactory receptors, family 2

OR2L3 OR2T35 OR2W1 OR2T2

1.90e-03113844149
GeneFamilySolute carriers

SLC6A17 SLC6A15 SLC12A1 SLC12A3 SLC18A1 SLC22A3 SLC28A1

2.41e-03395847752
GeneFamilyBeta 3-glycosyltransferases

B3GALT2 B3GALT1

5.51e-0324842426
GeneFamilyTransient receptor potential cation channels

TRPM7 TRPV3

7.45e-0328842249
GeneFamilySorting nexins|PX-BAR domain containing

SNX4 SNX9

7.98e-0329842754
GeneFamilyCyclins|Mediator complex

MED12L MED12

1.03e-02338421061
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

4.86e-071841147369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 GPR39 TTC6 MYO5C PTPRK SLC22A3 MAPK10

5.04e-07185114798b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

5.04e-071851147cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ABCC4 GPR39 TTC6 MYO5C PTPRK SLC22A3 MAPK10

5.41e-07187114781cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

5.61e-071881147c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

6.24e-071911147e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

6.46e-071921147499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

6.46e-071921147efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

8.22e-0719911475cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 GPR39 PIWIL4 PKD1L3 TTC6 FGFR2

1.07e-0613011466434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CYP7A1 DNAH2 PIWIL4 TSPAN32 SLC28A1

4.16e-06931145af489f0dd76c3c1a84d164283149f550a7ece91c
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CYP7A1 DNAH2 PIWIL4 TSPAN32 SLC28A1

4.16e-06931145c1d0afcfa37c2dcbb12189b4ce56ae7c4bb7ba30
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CYP7A1 DNAH2 PIWIL4 TSPAN32 SLC28A1

4.16e-069311450ea74c2820372d60d3804bf2c8bb0d03733dff98
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 MAPK10

4.42e-061661146c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2

6.81e-061791146cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

B3GALT2 TMEM101 WDR53 THADA METTL8 IFT80

7.26e-061811146b193f3606554adc55c5906219d114288bb1f978a
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 SNX4 HTR7 CSNK2A1 LHFPL2 SMAD3

9.01e-0618811466468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 SNX4 HTR7 CSNK2A1 LHFPL2 SMAD3

9.01e-0618811467a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 SNX4 HTR7 CSNK2A1 LHFPL2 SMAD3

9.01e-0618811469cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

GPR39 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

9.01e-061881146707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

ABCC4 TTC6 PTPRK SLC22A3 FGFR2 MAPK10

9.29e-061891146dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2

9.57e-0619011468aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 TTC6 PTPRK SLC22A3 FGFR2 MAPK10

9.86e-06191114634cc997e4e5c727495f321e6807a84aa124da486
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

9.86e-061911146a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

GPR39 TTC6 MYO5C SLC22A3 FGFR2 MAPK10

9.86e-061911146276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2

9.86e-061911146ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2

9.86e-061911146d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ABCC4 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

1.02e-05192114658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2

1.05e-051931146a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 GNB5 MED12L TAGLN2

1.05e-0519311463d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPR39 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

1.08e-05194114653f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPR39 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

1.11e-0519511469406866f99555198a9be311fbd65751b70f35446
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 GNB5 MED12L TAGLN2

1.14e-05196114666ba31b74953726e9c314f6d8fe3f75d3762e23a
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 MYO5C PTPRK SLC22A3 FGFR2 MAPK10

1.21e-051981146f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPR39 TTC6 MYO5C PTPRK SLC22A3 FGFR2

1.25e-0519911465f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TSPAN32 FAM217A CLPTM1L SLC12A3 MIPEP TAGLN2

1.28e-052001146e4be88bcef2738915f711b32c95e9c613e7edf96
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ENPP6 PKD1L1 PIWIL4 SLC28A1

3.33e-057111442220e1b02baa71961cfc85536bafeb313e588bf3
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ENPP6 PKD1L1 PIWIL4 SLC28A1

3.33e-05711144cc5de8bbcfefa2bf93cc137c74b49a745d5da229
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 SLC6A17 TMEM101 SLC12A3 MED12L

5.74e-0516011458bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 SLC6A17 TMEM101 SLC12A3 MED12L

5.74e-0516011452d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DOCK8 PTGER3 TMEM101 SLC12A3

5.74e-0516011451e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH2 CSMD3 TTC6 SLC28A1 NLRP8

7.03e-0516711453edb0570e583bb527165bcd8a4c25a042054043b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

ABCC4 TTC6 PTPRK SLC22A3 FGFR2

7.64e-051701145269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

KRBA2 TBL3 TMEM101 MIPEP DPY19L4

8.30e-051731145d11705e56b6b21eec963ea224717f27680c781ed
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPR39 MYO5C PTPRK SLC22A3 FGFR2

8.30e-051731145b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANO4 ABCC4 DOCK8 PTGER3 TMEM101

8.76e-0517511451d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 GPR39 TTC6 PTPRK SLC22A3

9.49e-051781145f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPR39 TTC6 PTPRK SLC22A3 FGFR2

9.75e-051791145815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HCN4 HCN1 GPR173 TTC6 SLC18A1

9.75e-0517911458ce5000088b727783a0619baa16a2cd036d21f54
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DOCK8 CSMD3 PTGER3 TMEM101

1.03e-04181114530729f0364f719c044712a51453e22dc2c1a232b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 SLC6A17 PTGER3 TMEM101 SLC12A3

1.03e-041811145e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

TTC6 PTPRK SLC22A3 FGFR2 MAPK10

1.03e-041811145c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPR39 TTC6 PTPRK SLC22A3 MAPK10

1.11e-041841145102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCelldroplet-Liver-Hepatocytes-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A15 TTC6 MYO5C MAPK13 PSAPL1

1.11e-0418411455b0695b1fbc8e4230f8f0669373ea10af82a0130
ToppCelldroplet-Liver-Hepatocytes-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A15 TTC6 MYO5C MAPK13 PSAPL1

1.11e-0418411456485d0d34bdab337b747c0ea2d75e8fad8486b4d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ABCC4 TTC6 PTPRK SLC22A3 MAPK10

1.14e-041851145673f0c688ae6984bc8027df2da335787924f4137
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPR39 TTC6 MYO5C PTPRK SLC22A3

1.17e-0418611452ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO4 HCN1 PIWIL4 CSMD3 TMC3

1.20e-04187114516e55d802fc4e71878305e61ad03806aabd59537
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5C SLC12A1 SLC12A3 SNX9 SMAD3

1.20e-04187114577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 PTGER3 TMEM101 SLC12A3 MED12L

1.23e-041881145bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GPR39 TTC6 MYO5C SLC22A3 FGFR2

1.23e-041881145beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 GPR39 PTGER3 MYO5C SLC12A3

1.26e-041891145975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 GPR39 PTGER3 MYO5C SLC12A3

1.26e-0418911457eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO4 CPT1B PTGER3 MYO5C SLC12A1

1.29e-04190114568ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

GPR39 TTC6 MYO5C SLC22A3 MAPK10

1.29e-04190114527a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO4 CPT1B PTGER3 MYO5C SLC12A1

1.29e-041901145010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-early_MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 MED12L TAGLN2

1.32e-0419111453839bf57419d3ec3d4464277bb33301d2b7d701f
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 PTGER3 GNB5 MED12L TAGLN2

1.32e-0419111457edc22e7e70697fb22690699efb352577162709b
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

GPR39 TTC6 PTPRK SLC22A3 FGFR2

1.35e-041921145d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPR39 TTC6 PTPRK SLC22A3 FGFR2

1.35e-04192114529f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 TTC6 PTPRK SLC22A3 FGFR2

1.35e-041921145fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 PTPRK SLC22A3 FGFR2 MAPK10

1.39e-041931145fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

ABCC4 PTPRK SLC22A3 FGFR2 MAPK10

1.39e-041931145738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 PTPRK SLC22A3 FGFR2 MAPK10

1.39e-041931145f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CSMD3 SLC12A1 IPO13 MAPK10 SMAD3

1.39e-041931145088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell10x5'v1-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 MED12L TAGLN2

1.42e-041941145245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPR39 PTGER3 SLC12A1 FGFR2 MAPK10

1.42e-04194114593c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 MED12L TAGLN2

1.42e-041941145216cba1a04b1a24b080322bc950e7fa2dade5ff1
ToppCellHSPCs-Mk_prog.|World / Lineage and Cell class

SLC6A15 TSPAN32 PTGER3 SLC22A3 MED12L

1.42e-0419411455049f4f102844d766eca577e809cf21f7908a9d2
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-early_MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 MED12L TAGLN2

1.45e-041951145fa5fc6f605deb5cae96eec14ba4000b19f877ba6
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 MED12L TAGLN2

1.45e-0419511451e794839a251fbc6e6ce419b4c457ead35a04735
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 PTGER3 TMEM101 SLC12A3 MED12L

1.45e-041951145a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 GPR39 PTPRK SLC22A3 FGFR2

1.49e-041961145ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-early_MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 MED12L TAGLN2

1.49e-041961145fc541e328aed28e84d5b3835169c60da0d64cddc
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

ABCC4 TTC6 MYO5C SLC22A3 FGFR2

1.53e-04197114544a59dfb889577b3160a5b13ada1276771a00241
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCC4 TTC6 MYO5C SLC22A3 FGFR2

1.53e-0419711451485933986921ff45669d9b7501c8d17050b3e97
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCC4 TSPAN32 PTGER3 MED12L TAGLN2

1.56e-041981145fcf53d6ac2e442400fa0c07c6de72e00a9143ba2
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCC4 TTC6 MYO5C SLC22A3 FGFR2

1.56e-041981145285f729140b1df029c24f6ca1d2438470ac51794
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 PTPRK SLC22A3 FGFR2 MAPK10

1.56e-0419811452e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC6A17 PKD1L1 TSPAN32 SLC12A3 MED12L

1.60e-041991145565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPR39 MYO5C PTPRK SLC22A3 MAPK10

1.60e-041991145725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPR39 MYO5C PTPRK SLC22A3 FGFR2

1.60e-0419911458587bd98de7767a575088afbea07a1feb4516b9b
ToppCell(02)_MMP9/10+-(1)_GFP|(02)_MMP9/10+ / shred by cell type by condition

ACADVL PTPRK VCAN TRPV3 TAGLN2

1.60e-041991145448ba982be804007f991d469eca9d885b21ae499
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABCC4 TTC6 MYO5C SLC22A3 FGFR2

1.64e-042001145e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABCC4 DOCK8 CHST11 MED12L LHFPL2

1.64e-042001145a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABCC4 DOCK8 CHST11 MED12L LHFPL2

1.64e-042001145dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABCC4 DOCK8 CHST11 MED12L LHFPL2

1.64e-0420011453bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABCC4 DOCK8 CHST11 MED12L LHFPL2

1.64e-04200114521bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABCC4 DOCK8 CHST11 MED12L LHFPL2

1.64e-042001145a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABCC4 DOCK8 CHST11 MED12L LHFPL2

1.64e-04200114533036d21c1c82109284473a515c4f890b33fdd5c
Diseasesick sinus syndrome (implicated_via_orthology)

HCN4 HCN1

3.83e-0531062DOID:13884 (implicated_via_orthology)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

HCN4 VCAN MED12 SMAD3

4.02e-05531064C4707243
DiseaseDrug habituation

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C0013170
DiseaseDrug abuse

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C0013146
DiseasePrescription Drug Abuse

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C4316881
DiseaseSubstance-Related Disorders

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C0236969
DiseaseDrug Use Disorders

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C0013222
DiseaseDrug Dependence

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C1510472
DiseaseSubstance Dependence

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C0038580
DiseaseSubstance Use Disorders

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.10e-051151065C0029231
DiseaseSubstance abuse problem

ANO4 ABCC4 CSMD3 MYO5C SLC22A3

6.36e-051161065C0740858
DiseaseOvarian Serous Adenocarcinoma

TRPM7 TRRAP FGFR2

7.57e-05231063C1335177
Diseasetestosterone measurement

B3GALT1 MYO5A ACADVL CYP7A1 DNAH2 CSMD3 GPR180 PNMA6F THADA SLC22A3 SLC28A1 LHFPL2 MAPK10 MED12

1.90e-04127510614EFO_0004908
Diseaseanxiety, vitamin D measurement

DOCK8 GNB5

2.65e-0471062EFO_0004631, EFO_0005230
Diseaseserum gamma-glutamyl transferase measurement

TRPM7 CYP7A1 GPR39 SLC6A15 CSMD3 MPRIP THADA LHFPL2 FGFR2 IFT80 SNX9

4.53e-0491410611EFO_0004532
DiseaseLiver Cirrhosis

TRPM7 TAGLN2 FGFR2 SMAD3

5.29e-041031064C0023890
Diseaseresponse to hydrochlorothiazide, diastolic blood pressure change measurement

PKD1L1 TTC6

5.65e-04101062EFO_0005202, EFO_0006945
DiseaseFibrosis, Liver

TRPM7 TAGLN2 FGFR2 SMAD3

5.69e-041051064C0239946
Diseaseprostate specific antigen measurement

ABCC4 SLC6A15 CLPTM1L THADA FGFR2

6.00e-041881065EFO_0004624
DiseaseOther specified cardiac arrhythmias

HCN4 SCN10A

6.88e-04111062C0348626
DiseaseNodal rhythm disorder

HCN4 SCN10A

6.88e-04111062C0264893
DiseaseEctopic rhythm

HCN4 SCN10A

6.88e-04111062C1399226
DiseaseCARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)

HCN4 SCN10A

6.88e-04111062C2748542
DiseaseOligospermia

PIWIL4 DICER1

8.24e-04121062C0028960
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

SMAD1 SMAD5

9.72e-04131062DOID:0050787 (implicated_via_orthology)
DiseaseBrugada Syndrome 1

HCN4 SCN10A

9.72e-04131062C4551804
DiseaseP wave duration

HCN1 SCN10A

1.30e-03151062EFO_0005094
DiseaseSinus Node Dysfunction (disorder)

HCN4 SCN10A

1.30e-03151062C0428908
Diseasediverticular disease

B3GALT1 SLC6A17 SLC6A15 MED12L SMAD3

1.65e-032361065EFO_0009959
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

ABCC4 CYP7A1

1.68e-03171062DOID:13619 (biomarker_via_orthology)
Diseaseunipolar depression, response to bupropion, mood disorder

ENPP6 HCN1

2.10e-03191062EFO_0003761, EFO_0004247, EFO_0006326
DiseaseMental Depression

HTR7 HCN1 SLC18A1 FGFR2 MED12

2.27e-032541065C0011570
Diseasestem Cell Growth Factor beta measurement

CHST11 CFAP61 ZNF44

2.52e-03751063EFO_0008292
Diseasenose morphology measurement, mouth morphology measurement

ANO4 OR4D5

2.57e-03211062EFO_0007843, EFO_0007955
Diseaseapolipoprotein B measurement

ACADVL PMPCB CYP7A1 PKD1L3 TMEM101 THADA SLC18A1 SLC22A3

2.73e-036631068EFO_0004615
DiseaseEndometrioma

ANO4 ABCC4 DICER1 VCAN

2.75e-031611064C0269102
DiseaseEndometriosis

ANO4 ABCC4 DICER1 VCAN

2.75e-031611064C0014175
Diseaseanxiety disorder (implicated_via_orthology)

HTR7 HCN1

2.82e-03221062DOID:2030 (implicated_via_orthology)
DiseaseBrugada Syndrome (disorder)

HCN4 SCN10A

3.35e-03241062C1142166

Protein segments in the cluster

PeptideGeneStartEntry
MSLCSWVNVVVGRMT

CFAP61

731

Q8NHU2
ETITCILMDGKVMWS

CSMD3

871

Q7Z407
WMKLGNTGAMRRCVK

CTC1

916

Q2NKJ3
MFINIKSILWMCSTL

VCAN

1

P13611
MVMAALSLVAACWGR

C19orf47

1

Q8N9M1
NLTLKTLMGMRWVAT

B3GALT1

151

Q9Y5Z6
TLMGMRWVATFCSKA

B3GALT1

156

Q9Y5Z6
CWNMKMMIKTLATLV

ADCY10

851

Q96PN6
LCMQMGIIMVLKQTW

ANO4

646

Q32M45
WCADKVAGMMVRELQ

DICER1

316

Q9UPY3
KNLIQCWRECMAMSS

AOX1

971

Q06278
SKRMCVLMITGSWII

OR2L3

136

Q8NG85
KKAMVWDMRSGQCVQ

GNB5

261

O14775
NGIALMMWNTFLVKR

RAB3GAP2

1051

Q9H2M9
MVSWGRFICLVVVTM

FGFR2

1

P21802
DMLHVVQKEWMRLCT

PMPCB

376

O75439
MQMARLLGLCAWARK

DHRS4L2

1

Q6PKH6
RMLMDIWTQKGNISL

OR10AG1

71

Q8NH19
LMNRRVCLFMVVGSW

OR2T2

136

Q6IF00
MTSGIRRNWIQTIMK

MPRIP

466

Q6WCQ1
TLAVCWMPNQIRRIM

GPR39

291

O43194
VPMVRATWLIKMTCA

MED12L

151

Q86YW9
IWSVGCIMGEMVRHK

MAPK10

246

P53779
PVVCWMVCSGLKQQM

NLRP8

396

Q86W28
TLNVLWKMCGIDVHM

KIAA1109

3446

Q2LD37
CNVTMVGKLWFVLTM

GJD4

16

Q96KN9
WMTSRMKFLTCTQGP

PNMA6F

336

A0A0J9YX94
CLKMIIMIWSISLAN

OR2W1

141

Q9Y3N9
CVALVVASWIMGVMH

OR4K2

141

Q8NGD2
IWMGNLLIMISITCT

OR4P4

36

Q8NGL7
AIQLMGIMCVLSVCW

PTGER3

281

P43115
RWHQRMSKMLQEICT

GOLGA8Q

251

H3BV12
CGMILQEAMKWAPTV

PI4KA

1061

P42356
IWSVGCIMAEMLTGK

MAPK13

206

O15264
MCHVIVTCRSMLWTL

LHFPL2

1

Q6ZUX7
VPVMRAAWLIKMTCA

MED12

151

Q93074
IMSCGMDHSLKLWRI

EED

251

O75530
SLCMGWTIVRMKKSQ

GPR180

261

Q86V85
MNRRVCLFMVVGSWV

OR2T35

136

Q8NGX2
CRMLLKRMVIVWSTG

NOC2L

291

Q9Y3T9
DVWLTMLSMIVGATC

HCN4

491

Q9Y3Q4
MCAALVGMAWLVSHV

OR1K1

141

Q8NGR3
ALTLMGMFQWCVRQS

ABCC4

986

O15439
FRLVNTKCMVLVDMW

PAN3

526

Q58A45
NLTIKTLMGMNWVAT

B3GALT2

226

O43825
NGIEERMSMVWEKCV

DPYSL4

356

O14531
DLWITMLSMIVGATC

HCN1

371

O60741
VKEQTMWACLAAMAV

IFT80

611

Q9P2H3
DTTRNLMICFLWIMK

DOCK8

1291

Q8NF50
QLMGAIKLCTGWMVT

DPY19L4

586

Q7Z388
WSLGCMLASMIFRKE

CSNK2A1

216

P68400
AAVICMAWTLSVAMA

GPR173

141

Q9NS66
LSLWVCEAQTVKKMM

GEN1

31

Q17RS7
MMTTSLIWGIAIAAC

CYP7A1

1

P22680
LPNNGSWSRVMCMLK

ENPP6

401

Q6UWR7
SMVKMVSTRCLPWRS

FAM217A

426

Q8IXS0
LAAKSLCMWVRAMEL

DNAH2

3191

Q9P225
QMRKCTLILMFAWFT

SLC22A3

346

O75751
IHKTSQCMWLMQALG

IPO13

581

O94829
MNMIWRNSISCLRLG

METTL8

1

Q9H825
MVCLMALGFAWKRRA

PKD1L1

2186

Q8TDX9
MHGKTSNLTRIWAMC

CPT1B

141

Q92523
SCHWAKGLRFMQMVR

KRBA2

381

Q6ZNG9
MNQTVCALLMAASWV

OR4D5

136

Q8NGN0
RMIWQEQSACIVMVT

PTPRK

971

Q15262
MTIISQWVCGVLMAV

OR4C16

131

Q8NGL9
LWGMIMTSSICLRQT

MT-ND4

266

P03905
MNRRTCVQIAAGSWM

OR13F1

136

Q8NGS4
TMNRQVCGLLVAMAW

OR4C5

156

Q8NGB2
TAIGMMTRIAVLKWL

VAC14

411

Q08AM6
SWMLLSCLMLLSQVQ

REG3A

11

Q06141
AVMQISMCKKGIQVW

SNX4

426

O95219
LQAWMTRMCRHPVIS

SNX9

331

Q9Y5X1
WVMVCLAMIKGIQSS

SLC6A15

236

Q9H2J7
VCMNVVQKLDHWLMS

PSAPL1

296

Q6NUJ1
AQMVLVCCWRSMKEV

THADA

1046

Q6YHU6
MANIRCRPWTMGQKL

TMC3

61

Q7Z5M5
RVLIHWMTLCQTQMK

TMEM126B

181

Q8IUX1
LWEGKNMACVQRTLM

TAGLN2

116

P37802
MSMVKSFVQWLGCRS

OGA

651

O60502
RTTLKLQGQMIWMES

GUCY1B2

271

O75343
AMQMTCKLGGELWAV

PIWIL4

596

Q7Z3Z4
TLLLCNMVINVMFWK

PKD1L3

911

Q7Z443
KGVLVRCMLNIWGVM

SLC12A1

181

Q13621
VLKWLFRMMSVHTDC

SLF2

806

Q8IX21
MRMQAALVGWACTTL

REELD1

1

A0A1B0GV85
LTKMCTIRMSFVKGW

SMAD5

406

Q99717
LTKMCTIRMSFVKGW

SMAD1

406

Q15797
AWKVTDECIQIMGGM

ACADVL

426

P49748
GKCMAKMILSVWLLS

HTR7

196

P34969
KSMIGMSTKAVLWRC

CLPTM1L

316

Q96KA5
VACTNWKRLMMVLTG

CHST11

126

Q9NPF2
SWLQVPMMVRGLCTA

CLEC20A

236

Q6ZU45
GFLMWRNSKVMNIVS

YIPF1

181

Q9Y548
SWNRAEMTMCALLAK

TTC6

51

Q86TZ1
LMSRAVASMVWKECF

MIPEP

636

Q99797
IENMWACMEVGQKSI

SCN10A

851

Q9Y5Y9
LTRMCTIRMSFVKGW

SMAD3

366

P84022
MGPWSRVRVAKCQML

TSPAN32

1

Q96QS1
RIWRMNKAGQVMCVA

TBL3

401

Q12788
RVWSMDNMICTQTLL

TRAF7

626

Q6Q0C0
FGWVKGVMIRCMLNI

SLC12A3

136

P55017
SLVSCGLDMQVMLWS

WDR53

151

Q7Z5U6
GLDMQVMLWSLQKAR

WDR53

156

Q7Z5U6
LKIAWLMQVTMGTTA

SLC28A1

291

O00337
GRMFVLIWAMCISVK

TRPV3

486

Q8NET8
KMTLCLLVAWSIVGM

SLC6A17

226

Q9H1V8
RSGSQCLSKWKIMMG

SNAPC4

486

Q5SXM2
CQQLWRMGMLGTRVL

XKR5

181

Q6UX68
RQAWEVIKCFLVAMM

TRRAP

961

Q9Y4A5
MRETIRNLNCIGMKW

ZNF44

81

P15621
MVTCGTDRIVKIWDM

WDFY1

381

Q8IWB7
LIWACLMKRQVMARF

TRPM7

626

Q96QT4
MASKIGSRRWMLQLI

TMEM101

1

Q96IK0
LDTLMWGMLNRKAQV

ZRANB3

451

Q5FWF4
NKMGRWLCSLIGMLV

SLC18A1

361

P54219
LRKDMCSWSKGMQIR

MYO5A

1706

Q9Y4I1
LRQSCVMVQKHMRGW

MYO5C

756

Q9NQX4