Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	MIOX ALOX5 ALOX12B	1.60e-05	26	38	3	GO:0016701
GeneOntologyMolecularFunction	arachidonate 12(S)-lipoxygenase activity	ALOX5 ALOX12B	2.11e-05	4	38	2	GO:0004052
GeneOntologyMolecularFunction	histone acetyltransferase activity	TAF9 KAT6B KAT6A	1.24e-04	51	38	3	GO:0004402
GeneOntologyMolecularFunction	histone H3K14 acetyltransferase activity	KAT6B KAT6A	1.26e-04	9	38	2	GO:0036408
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	TAF9 KAT6B KAT6A	1.56e-04	55	38	3	GO:0061733
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	TAF9 KAT6B KAT6A	2.02e-04	60	38	3	GO:0034212
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	KAT6B KAT6A	3.65e-04	15	38	2	GO:0010484
GeneOntologyMolecularFunction	N-acetyltransferase activity	TAF9 KAT6B KAT6A	4.38e-04	78	38	3	GO:0008080
GeneOntologyMolecularFunction	N-acyltransferase activity	TAF9 KAT6B KAT6A	9.59e-04	102	38	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	TAF9 KAT6B KAT6A	1.01e-03	104	38	3	GO:0016407
GeneOntologyMolecularFunction	opsonin binding	CFH MASP2	1.03e-03	25	38	2	GO:0001846
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ALOX5 ALOX12B	1.03e-03	25	38	2	GO:0016702
GeneOntologyMolecularFunction	complement binding	CFH MASP2	1.69e-03	32	38	2	GO:0001848
GeneOntologyMolecularFunction	iron ion binding	MIOX ALOX5 ALOX12B	3.84e-03	166	38	3	GO:0005506
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	TAF9 TAF9B	4.40e-03	52	38	2	GO:0016251
GeneOntologyMolecularFunction	NADP binding	MIOX NNT	6.21e-03	62	38	2	GO:0050661
GeneOntologyMolecularFunction	transition metal ion binding	AGBL4 RAG2 MIOX ALOX5 ALOX12B KAT6A APOBEC3H	6.48e-03	1189	38	7	GO:0046914
GeneOntologyMolecularFunction	general transcription initiation factor activity	TAF9 TAF9B	7.42e-03	68	38	2	GO:0140223
GeneOntologyCellularComponent	histone acetyltransferase complex	TAF9 TAF9B KAT6B KAT6A	2.80e-05	94	39	4	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	TAF9 TAF9B KAT6B KAT6A	4.16e-05	104	39	4	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	TAF9 TAF9B KAT6B KAT6A	5.00e-05	109	39	4	GO:1902493
GeneOntologyCellularComponent	MOZ/MORF histone acetyltransferase complex	KAT6B KAT6A	7.08e-05	7	39	2	GO:0070776
GeneOntologyCellularComponent	H3 histone acetyltransferase complex	KAT6B KAT6A	9.43e-05	8	39	2	GO:0070775
GeneOntologyCellularComponent	transcription factor TFTC complex	TAF9 TAF9B	5.09e-04	18	39	2	GO:0033276
MousePheno	micrognathia	CACNA1S DNAH5 PGAP1 KAT6A	9.60e-06	68	28	4	MP:0002639
MousePheno	decreased cerebral cortex pyramidal cell number	KAT6B EPG5	5.77e-05	6	28	2	MP:0009974
Domain	TFIID-31	TAF9 TAF9B	1.21e-05	3	38	2	IPR003162
Domain	TFIID-31kDa	TAF9 TAF9B	1.21e-05	3	38	2	PF02291
Domain	MOZ_SAS	KAT6B KAT6A	4.02e-05	5	38	2	PF01853
Domain	HAT_MYST-type	KAT6B KAT6A	4.02e-05	5	38	2	IPR002717
Domain	MYST_HAT	KAT6B KAT6A	4.02e-05	5	38	2	PS51726
Domain	LIPOXYGENASE_2	ALOX5 ALOX12B	6.02e-05	6	38	2	PS00081
Domain	LipOase	ALOX5 ALOX12B	6.02e-05	6	38	2	IPR000907
Domain	LipOase_Fe_BS	ALOX5 ALOX12B	6.02e-05	6	38	2	IPR020833
Domain	LipOase_CS	ALOX5 ALOX12B	6.02e-05	6	38	2	IPR020834
Domain	LipOase_mml	ALOX5 ALOX12B	6.02e-05	6	38	2	IPR001885
Domain	LIPOXYGENASE_1	ALOX5 ALOX12B	6.02e-05	6	38	2	PS00711
Domain	LipOase_C	ALOX5 ALOX12B	6.02e-05	6	38	2	IPR013819
Domain	Lipoxygenase	ALOX5 ALOX12B	6.02e-05	6	38	2	PF00305
Domain	LIPOXYGENASE_3	ALOX5 ALOX12B	6.02e-05	6	38	2	PS51393
Domain	DUF4599	SPATA31C2 SPATA31C1	2.63e-04	12	38	2	PF15371
Domain	DUF4599	SPATA31C2 SPATA31C1	2.63e-04	12	38	2	IPR027970
Domain	H15	KAT6B KAT6A	3.10e-04	13	38	2	SM00526
Domain	H15	KAT6B KAT6A	3.10e-04	13	38	2	PS51504
Domain	Histone_H1/H5_H15	KAT6B KAT6A	3.61e-04	14	38	2	IPR005818
Domain	LH2	ALOX5 ALOX12B	6.04e-04	18	38	2	SM00308
Domain	PLAT	ALOX5 ALOX12B	8.26e-04	21	38	2	PF01477
Domain	PLAT	ALOX5 ALOX12B	8.26e-04	21	38	2	PS50095
Domain	PLAT/LH2_dom	ALOX5 ALOX12B	8.26e-04	21	38	2	IPR001024
Domain	-	ALOX5 ALOX12B	8.26e-04	21	38	2	2.60.60.20
Domain	ZF_PHD_2	RAG2 KAT6B KAT6A	9.45e-04	95	38	3	PS50016
Domain	ZF_PHD_1	RAG2 KAT6B KAT6A	9.74e-04	96	38	3	PS01359
Domain	-	KAT6B KAT6A	2.99e-03	40	38	2	3.40.630.30
Domain	Znf_FYVE_PHD	RAG2 KAT6B KAT6A	3.29e-03	147	38	3	IPR011011
Domain	Acyl_CoA_acyltransferase	KAT6B KAT6A	3.78e-03	45	38	2	IPR016181
Domain	Sushi	CFH MASP2	5.01e-03	52	38	2	PF00084
Domain	CCP	CFH MASP2	5.40e-03	54	38	2	SM00032
Domain	SUSHI	CFH MASP2	5.79e-03	56	38	2	PS50923
Domain	Sushi_SCR_CCP_dom	CFH MASP2	6.00e-03	57	38	2	IPR000436
Domain	-	TAF9 TAF9B	8.68e-03	69	38	2	1.10.20.10
Domain	PHD	KAT6B KAT6A	1.02e-02	75	38	2	PF00628
Domain	Znf_PHD-finger	KAT6B KAT6A	1.13e-02	79	38	2	IPR019787
Domain	Histone-fold	TAF9 TAF9B	1.24e-02	83	38	2	IPR009072
Domain	PHD	KAT6B KAT6A	1.41e-02	89	38	2	SM00249
Pubmed	In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.	TAF9 TAF9B	1.29e-06	2	40	2	12837753
Pubmed	ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.	KAT6B KAT6A	1.29e-06	2	40	2	39505971
Pubmed	Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.	KAT6B KAT6A	1.29e-06	2	40	2	27185879
Pubmed	The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.	KAT6B KAT6A	1.29e-06	2	40	2	24150941
Pubmed	MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.	KAT6B KAT6A	3.87e-06	3	40	2	36754959
Pubmed	Interleukin-17D and Nrf2 mediate initial innate immune cell recruitment and restrict MCMV infection.	RAG2 IL17D	3.87e-06	3	40	2	30209334
Pubmed	Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.	KAT6B KAT6A	3.87e-06	3	40	2	23063713
Pubmed	Human TAFII31 protein is a transcriptional coactivator of the p53 protein.	TAF9 TAF9B	3.87e-06	3	40	2	7761466
Pubmed	Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.	RAG2 IL17D	7.73e-06	4	40	2	27545889
Pubmed	Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).	KAT6B KAT6A	7.73e-06	4	40	2	21880731
Pubmed	The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.	KAT6B KAT6A	7.73e-06	4	40	2	17980166
Pubmed	Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.	KAT6B KAT6A	1.29e-05	5	40	2	17182677
Pubmed	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.	KAT6B KAT6A	1.29e-05	5	40	2	11965546
Pubmed	Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence.	RAG2 IL22RA1	1.29e-05	5	40	2	35845169
Pubmed	The chromatin regulator Brpf1 regulates embryo development and cell proliferation.	KAT6B IL22RA1 KAT6A	1.35e-05	40	40	3	25773539
Pubmed	MOZ is essential for maintenance of hematopoietic stem cells.	MPL KAT6A	1.93e-05	6	40	2	16702405
Pubmed	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.	KAT6B KAT6A	2.70e-05	7	40	2	18794358
Pubmed	TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.	TAF9 TAF9B	4.62e-05	9	40	2	15899866
Pubmed	Acetylation of HIV-1 integrase by p300 regulates viral integration.	KAT6B KAT6A	7.05e-05	11	40	2	16096645
Pubmed	Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22.	RAG2 IL22RA1	1.16e-04	14	40	2	36630911
Pubmed	Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.	TAF9 TAF9B	1.95e-04	18	40	2	29111974
Pubmed	Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module.	TAF9 TAF9B	2.42e-04	20	40	2	27601583
Pubmed	Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.	TAF9 TAF9B	2.42e-04	20	40	2	17884155
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	CFH MASP2	5.87e-04	31	40	2	19344414
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	ARHGAP32 TAF9 KAT6B PREPL KAT6A	6.37e-04	608	40	5	16713569
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ARHGAP32 PRAMEF17 SLC18A1 PGAP1	7.93e-04	363	40	4	14691545
Pubmed	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.	KAT6B KAT6A	1.08e-03	42	40	2	16387653
Cytoband	1q32	CFH CACNA1S	8.48e-04	49	40	2	1q32
Cytoband	1p36.11	IL22RA1 CNR2	1.63e-03	68	40	2	1p36.11
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PRAMEF17 IL22RA1 CNR2 MASP2	2.87e-03	681	40	4	chr1p36
GeneFamily	Arachidonate lipoxygenases	ALOX5 ALOX12B	2.97e-05	6	26	2	407
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT6B KAT6A	2.36e-04	16	26	2	66
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT6B KAT6A	2.67e-04	17	26	2	486
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH MASP2	3.02e-03	57	26	2	1179
GeneFamily	PHD finger proteins	KAT6B KAT6A	7.37e-03	90	26	2	88
Drug	5,8,11-eicosatrienoic acid	ALOX5 ALOX12B CNR2	6.46e-06	22	38	3	CID000004028
Drug	AC1NR1PE	ALOX5 ALOX12B	1.62e-05	4	38	2	CID005283182
Drug	R 68 151	ALOX5 ALOX12B	1.62e-05	4	38	2	CID000132150
Drug	AC1L4ENC	ALOX5 ALOX12B	1.62e-05	4	38	2	CID000155619
Drug	C02639	ALOX5 ALOX12B	1.62e-05	4	38	2	CID000439776
Drug	19-hydroxy-PGB2	ALOX5 ALOX12B	2.70e-05	5	38	2	CID005283111
Drug	artonin E	ALOX5 ALOX12B	2.70e-05	5	38	2	CID005481962
Drug	6,7,4'-trihydroxyisoflavan	ALOX5 ALOX12B	2.70e-05	5	38	2	CID000125101
Drug	t-BuOOH	TAF9 TAF9B ALOX5	2.71e-05	35	38	3	CID000008033
Drug	REV 5901	ALOX5 ALOX12B CNR2	3.76e-05	39	38	3	CID000005059
Drug	tixocortolum	ALOX5 ALOX12B	4.05e-05	6	38	2	CID000162955
Drug	isamoxole	ALOX5 ALOX12B	4.05e-05	6	38	2	CID000042118
Drug	1-oleoyl-2-DHA-PC	ALOX5 ALOX12B	4.05e-05	6	38	2	CID006438829
Drug	CPHU	ALOX5 ALOX12B	4.05e-05	6	38	2	CID000124471
Drug	BW A797C	ALOX5 ALOX12B	4.05e-05	6	38	2	CID006439067
Drug	12-HPETE	ALOX5 ALOX12B CNR2	5.05e-05	43	38	3	CID000001415
Drug	AHR-5333	ALOX5 ALOX12B	5.67e-05	7	38	2	CID000173727
Drug	AC1L1G9H	ALOX5 ALOX12B	5.67e-05	7	38	2	CID000003587
Drug	knipholone	ALOX5 ALOX12B	5.67e-05	7	38	2	CID000442753
Drug	12-IODE	ALOX5 ALOX12B	5.67e-05	7	38	2	CID006450050
Drug	10,11-dihydro-LTB4	ALOX5 ALOX12B	5.67e-05	7	38	2	CID006439070
Drug	SRI 63-675	ALOX5 ALOX12B	7.55e-05	8	38	2	CID000122013
Drug	colneleic acid	ALOX5 ALOX12B	7.55e-05	8	38	2	CID006441681
Drug	Cgs 22745	ALOX5 ALOX12B	7.55e-05	8	38	2	CID006439321
Drug	AC1NUP73	ALOX5 ALOX12B	7.55e-05	8	38	2	CID005487167
Drug	htyA	ALOX5 ALOX12B	7.55e-05	8	38	2	CID000152267
Drug	CDNQ	ALOX5 ALOX12B	7.55e-05	8	38	2	CID000126468
Drug	15-HPEPE	ALOX5 ALOX12B	7.55e-05	8	38	2	CID006438853
Drug	AC1LCVO8	KAT6B KAT6A	7.55e-05	8	38	2	CID000656891
Drug	neobaicalein	ALOX5 ALOX12B	7.55e-05	8	38	2	CID000124211
Drug	AC1L1C7C	ALOX5 ALOX12B CNR2	7.96e-05	50	38	3	CID000001772
Drug	14,15-leukotriene A4	ALOX5 ALOX12B	9.69e-05	9	38	2	CID006439604
Drug	octadeca-9,12-dien-1-ol	ALOX5 ALOX12B	9.69e-05	9	38	2	CID000068168
Drug	U-56467	ALOX5 ALOX12B	9.69e-05	9	38	2	CID006439532
Drug	8,15-diHPETE	ALOX5 ALOX12B	9.69e-05	9	38	2	CID005283181
Drug	13-hydroxylinoleic acid	ALOX5 ALOX12B	9.69e-05	9	38	2	CID006438633
Drug	AC1NSXHC	ALOX5 ALOX12B	9.69e-05	9	38	2	CID005371969
Drug	U-66,855	ALOX5 ALOX12B	9.69e-05	9	38	2	CID000127235
Drug	5,6-methanoleukotriene A4	ALOX5 ALOX12B	9.69e-05	9	38	2	CID006439643
Drug	ODYA	ALOX5 ALOX12B	9.69e-05	9	38	2	CID000001931
Drug	KME-4	ALOX5 ALOX12B	9.69e-05	9	38	2	CID006438990
Drug	A-78773	ALOX5 ALOX12B	9.69e-05	9	38	2	CID000071460
Drug	propyl gallate	TAF9B ALOX5 ALOX12B	1.06e-04	55	38	3	CID000004947
Drug	9-HPODE	ALOX5 ALOX12B	1.21e-04	10	38	2	CID000001928
Drug	1,4-pentadiene	ALOX5 ALOX12B	1.21e-04	10	38	2	CID000011587
Drug	5,8,11-eicosatriynoic acid	ALOX5 ALOX12B CNR2	1.37e-04	60	38	3	CID000001781
Drug	JHW 015	ALOX5 CNR2	1.48e-04	11	38	2	ctd:C402944
Drug	acetone phenylhydrazone	ALOX5 ALOX12B	1.48e-04	11	38	2	CID000066026
Drug	Ity A	ALOX5 ALOX12B	1.48e-04	11	38	2	CID000188274
Drug	C04424	KAT6B KAT6A	1.48e-04	11	38	2	CID011953835
Drug	BW A137C	ALOX5 ALOX12B	1.48e-04	11	38	2	CID000129265
Drug	nonenal	ALOX5 ALOX12B	1.77e-04	12	38	2	CID003015503
Drug	C05118	KAT6B KAT6A	1.77e-04	12	38	2	CID000440565
Drug	C05119	KAT6B KAT6A	1.77e-04	12	38	2	CID000440566
Drug	AC1L9EUB	KAT6B KAT6A	2.09e-04	13	38	2	CID000443527
Drug	AC1NR1Q2	ALOX5 ALOX12B	2.09e-04	13	38	2	CID005283190
Drug	AC1L1BGZ	ALOX5 ALOX12B	2.09e-04	13	38	2	CID000001435
Drug	9-HETE	ALOX5 ALOX12B	2.09e-04	13	38	2	CID000001926
Drug	hypolaetin	ALOX5 ALOX12B	2.09e-04	13	38	2	CID005281648
Drug	ICI207968	ALOX5 ALOX12B	2.09e-04	13	38	2	CID000129095
Drug	AC1O4E1A	ALOX5 ALOX12B	2.09e-04	13	38	2	CID006365736
Drug	gossypetin	ALOX5 ALOX12B	2.44e-04	14	38	2	CID005280647
Drug	AC1L9EU8	KAT6B KAT6A	2.44e-04	14	38	2	CID000443526
Drug	AC1NR1LB	ALOX5 ALOX12B	2.44e-04	14	38	2	CID005283131
Drug	oxphaman	ALOX5 ALOX12B	2.44e-04	14	38	2	CID005464022
Drug	timegadine	ALOX5 ALOX12B	2.44e-04	14	38	2	CID000068902
Drug	5-HEPE	ALOX5 ALOX12B	2.44e-04	14	38	2	CID000001766
Drug	17-HdoHE	ALOX5 ALOX12B	2.44e-04	14	38	2	CID006439179
Drug	AC1LCVO5	KAT6B KAT6A	2.44e-04	14	38	2	CID000656890
Drug	8R-HpETE	ALOX5 ALOX12B	2.81e-04	15	38	2	CID005283170
Drug	Hex-3-enyl acetate	ALOX5 ALOX12B	2.81e-04	15	38	2	CID000015574
Drug	8(S),15(S)-diHETE	ALOX5 ALOX12B	2.81e-04	15	38	2	CID000001897
Drug	13-HpOTrE	ALOX5 ALOX12B	2.81e-04	15	38	2	CID005282866
Drug	Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	RBM48 KAT6B NNT KAT6A	2.95e-04	193	38	4	4846_DN
Drug	Praziquantel [55268-74-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A	C15orf39 RBM48 TDRD1 PGAP1	3.13e-04	196	38	4	7228_DN
Drug	Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; PC3; HT_HG-U133A	RAG2 CACNA1S ALOX12B MASP2	3.19e-04	197	38	4	4653_UP
Drug	AC1NR1M2	ALOX5 ALOX12B	3.21e-04	16	38	2	CID005283140
Drug	12R-HETrE	ALOX5 ALOX12B	3.21e-04	16	38	2	CID005283149
Drug	peroxylinolenic acid	ALOX5 ALOX12B	3.21e-04	16	38	2	CID006439905
Drug	hex-3-enal	ALOX5 ALOX12B	3.21e-04	16	38	2	CID000023234
Drug	sinensetin	ALOX5 ALOX12B	3.21e-04	16	38	2	CID000145659
Drug	Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A	SLC18A1 CNR2 PGAP1 MASP2	3.25e-04	198	38	4	7473_UP
Drug	Trichlorfon [52-68-6]; Up 200; 15.6uM; PC3; HT_HG-U133A	ZBTB38 RBM48 NNT PGAP1	3.31e-04	199	38	4	1797_UP
Drug	5,15-diHETE	ALOX5 ALOX12B	3.63e-04	17	38	2	CID005283158
Drug	cirsiliol	ALOX5 ALOX12B	3.63e-04	17	38	2	CID000160237
Drug	AC1L9ASI	KAT6B KAT6A	3.63e-04	17	38	2	CID000441230
Drug	dihydrotetrabenazine	SLC18A1 NNT	3.63e-04	17	38	2	CID000123836
Drug	capsazepine	ALOX5 ALOX12B CNR2	3.72e-04	84	38	3	CID002733484
Drug	FPL 57231	ALOX5 ALOX12B	4.08e-04	18	38	2	CID000122212
Drug	3-nonenal	ALOX5 ALOX12B	4.08e-04	18	38	2	CID005283336
Drug	BW540C	ALOX5 ALOX12B	4.08e-04	18	38	2	CID000134372
Drug	AC1O5PL5	ALOX5 ALOX12B	4.08e-04	18	38	2	CID006438380
Drug	L-651,392	ALOX5 ALOX12B	5.06e-04	20	38	2	CID000122182
Drug	TMK777	ALOX5 ALOX12B	5.06e-04	20	38	2	CID006438911
Drug	AC1L2P35	ALOX5 ALOX12B	5.06e-04	20	38	2	CID000125736
Drug	AC1O5S1P	ALOX5 ALOX12B	5.58e-04	21	38	2	CID006439617
Drug	AC1NRAUB	ALOX5 ALOX12B	5.58e-04	21	38	2	CID005288098
Drug	20-carboxyleukotriene B4	ALOX5 ALOX12B	5.58e-04	21	38	2	CID000001588
Drug	U-75302	ALOX5 ALOX12B	5.58e-04	21	38	2	CID006449854
Drug	BM 13.177	ALOX5 ALOX12B	6.13e-04	22	38	2	CID000051550
Disease	eosinophil cationic protein measurement	SPATA31C2 CFH SPATA31C1	1.10e-07	8	38	3	EFO_0010913
Disease	renal overload-type gout	SPATA31C2 SPATA31C1	2.41e-05	6	38	2	EFO_0021525
Disease	longitudinal alcohol consumption measurement	SPATA31C2 SPATA31C1	5.78e-05	9	38	2	EFO_0007645
Disease	egg allergy measurement, parental genotype effect measurement	SPATA31C2 SPATA31C1	1.25e-04	13	38	2	EFO_0005939, EFO_0007018
Disease	C-C motif chemokine 19 measurement	CFH DNAJC13	1.46e-04	14	38	2	EFO_0008047
Disease	Testicular Germ Cell Tumor	ALOX5 ALOX12B	1.46e-04	14	38	2	C1336708
Disease	amygdala volume change measurement	SPATA31C2 SPATA31C1	1.92e-04	16	38	2	EFO_0021490
Disease	Antibody Deficiency Syndrome	CFH EPG5	2.17e-04	17	38	2	C0003257
Disease	Pancreatic carcinoma	ALOX5 ALOX12B	2.72e-04	19	38	2	C0235974
Disease	selenium measurement, response to dietary selenium supplementation	DNAH5 SLC18A1	3.02e-04	20	38	2	EFO_0006331, EFO_0600021
Disease	Immunologic Deficiency Syndromes	CFH EPG5	4.02e-04	23	38	2	C0021051
Disease	pursuit maintenance gain measurement	SPATA31C2 SPATA31C1 EPG5	5.36e-04	123	38	3	EFO_0008433
Disease	bipolar disorder (is_implicated_in)	KAT6B SLC18A1	6.41e-04	29	38	2	DOID:3312 (is_implicated_in)
Disease	Complement deficiency disease	CFH MASP2	8.31e-04	33	38	2	C0272242
Disease	aspartate aminotransferase measurement	ANO4 CFH AGBL4 CACNA1S DNAJC13 SLC18A1	9.71e-04	904	38	6	EFO_0004736

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLEYCNAPKSRPPYR	TDRD1	976	Q9BXT4
LDKILPLFYPCQYYL	EPG5	1061	Q9HCE0
RPYYPRKALLCYQLT	APOBEC3H	21	Q6NTF7
LTPLPLYVCPVYWAY	POLE2	451	P56282
PAVPCLRKCYFPYLE	CFH	381	P08603
TPLKYCRYRDYRDPP	ANO4	851	Q32M45
RYLCLRYPPSYKALL	CNR2	131	P34972
IFSKDSCYLPPLRYP	RAG2	61	P55895
SNPYLPYSCELPLCY	RBM48	191	Q5RL73
SPYPQEYARLPKLYL	KAT6B	736	Q8WYB5
PQPLPFPKYLRCYRC	LY6G5C	51	Q5SRR4
YDRYVAICKPLQYPL	OR10AG1	111	Q8NH19
CPFLCLYYPQMLYIR	PRAMEF17	261	Q5VTA0
DPARYPRYLPEAYCL	IL17D	101	Q8TAD2
AYCPRPLYQYKPYQS	ARHGAP32	1611	A7KAX9
AYDRYVAICNPLLYP	OR5AC2	121	Q9NZP5
PYPQEYSRLPKLYLC	KAT6A	526	Q92794
LPVSYVPYYLPCPEI	GBGT1	31	Q8N5D6
RPLRCYIPKNPYQYQ	CACNA1S	1096	Q13698
WQRLPPKNVYYYRCP	AGBL4	126	Q5VU57
RALYQYCPIPIINYP	DNAJC13	1231	O75165
IRQRNKCLPIPYYYL	ALOX12B	676	O75342
KCLPIPYYYLDPVLI	ALOX12B	681	O75342
YPRPYPKLSSCTYSI	MASP2	201	O00187
LCYLSYRYVTKPPAP	IL22RA1	246	Q8N6P7
LRDPRFYSCPIYKKP	DNAH5	4576	Q8TE73
KLRPYYQGLIDKYCP	MIOX	266	Q9UGB7
KRPTDPPEYNYLYLL	NNT	586	Q13423
PPDRYCLTAPNYRLK	TAF9B	116	Q9HBM6
PPDRYCLTAPNYRLK	TAF9	116	Q16594
LLLPYFSYLRCDNPP	SPATA31C2	41	B4DYI2
KQLPYYYLSPDRIPN	ALOX5	656	P09917
TRPYYNPELPCRYLT	GCM2	356	O75603
LRYYFKLNPDPCKPL	PGAP1	841	Q75T13
LLLPYFSYLRCDNPP	SPATA31C1	41	P0DKV0
PLAAPKPVYRNPLCY	C15orf39	126	Q6ZRI6
FLQPPYNRPYKLYKT	NDUFV1-DT	236	Q8NBR9
FQLCSPIRPPKYYTY	PREPL	406	Q4J6C6
LYAYPREKPRACPLS	MPL	66	P40238
LKPSVYPYKLYRLLP	ZBTB38	556	Q8NAP3
YAPLCYYLRSPPAKE	SLC18A1	471	P54219