Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin conjugating enzyme activity

BIRC6 UBE2R2 UBE2A UBE2B

1.08e-04371344GO:0061631
GeneOntologyMolecularFunctionubiquitin-like protein conjugating enzyme activity

BIRC6 UBE2R2 UBE2A UBE2B

1.95e-04431344GO:0061650
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

2.28e-04821345GO:1990756
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

1.38e-05471375GO:0031462
DomainPRAME_family

PRAMEF25 PRAMEF15 PRAMEF4 PRAMEF27

8.01e-06191304IPR026271
DomainZU5

ANK2 SH3BP4 UNC5C

6.92e-05121303PF00791
DomainZU5_dom

ANK2 SH3BP4 UNC5C

6.92e-05121303IPR000906
DomainUQ_con

BIRC6 UBE2R2 UBE2A UBE2B

1.53e-04391304PF00179
DomainUBIQUITIN_CONJUGAT_1

BIRC6 UBE2R2 UBE2A UBE2B

1.69e-04401304PS00183
DomainUBIQUITIN_CONJUGAT_2

BIRC6 UBE2R2 UBE2A UBE2B

1.86e-04411304PS50127
DomainUBQ-conjugat_E2

BIRC6 UBE2R2 UBE2A UBE2B

1.86e-04411304IPR000608
Domain-

BIRC6 UBE2R2 UBE2A UBE2B

4.35e-045113043.10.110.10
DomainUBQ-conjugating_enzyme/RWD

BIRC6 UBE2R2 UBE2A UBE2B

5.04e-04531304IPR016135
DomainPWWP

BRPF3 PWWP2A PWWP3A

5.27e-04231303PF00855
DomainPWWP_dom

BRPF3 PWWP2A PWWP3A

5.27e-04231303IPR000313
DomainPWWP

BRPF3 PWWP2A PWWP3A

5.99e-04241303PS50812
DomainUBQ-conjugating_AS

UBE2R2 UBE2A UBE2B

6.78e-04251303IPR023313
DomainSNF2_N

CHD2 RAD54B HLTF

1.41e-03321303IPR000330
DomainSNF2_N

CHD2 RAD54B HLTF

1.41e-03321303PF00176
DomainZU5

ANK2 UNC5C

1.68e-0391302SM00218
DomainZU5

ANK2 UNC5C

2.09e-03101302PS51145
DomainDUF4599

SPATA31A7 SPATA31A5

3.03e-03121302PF15371
DomainDUF4599

SPATA31A7 SPATA31A5

3.03e-03121302IPR027970
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH7

4.14e-03141302IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH7

4.14e-03141302IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH7

4.14e-03141302IPR013602
DomainDHC_N2

DNAH2 DNAH7

4.14e-03141302PF08393
DomainMT

DNAH2 DNAH7

4.14e-03141302PF12777
DomainAAA_8

DNAH2 DNAH7

4.14e-03141302PF12780
DomainDHC_fam

DNAH2 DNAH7

4.76e-03151302IPR026983
DomainDynein_heavy

DNAH2 DNAH7

4.76e-03151302PF03028
DomainMyosin_N

MYH3 MYH7

4.76e-03151302PF02736
DomainDynein_heavy_dom

DNAH2 DNAH7

4.76e-03151302IPR004273
DomainMyosin_N

MYH3 MYH7

4.76e-03151302IPR004009
Domainfn3

MYOM1 FNDC3A FNDC1 NEO1 SORL1

5.54e-031621305PF00041
DomainMyosin_tail_1

MYH3 MYH7

6.84e-03181302PF01576
DomainMyosin_tail

MYH3 MYH7

6.84e-03181302IPR002928
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH3 MYH7 PPAN ANK2 CALD1 CTDSPL2 CHAF1A UBR4 DNAH2 ANKRD30B CHD2 CTAGE6 PDE10A PSMA8 PCF11 PHEX STRN TNRC18 INA H4C1 CEP112 UNC5C CFAP45 MTTP CTAGE15 ATP11C ARHGAP21 SYNCRIP BBOF1

4.28e-1314421382935575683
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDR2 ZNF326 PDGFRA MAP2 KIAA0232 BCR DNAH7 ANKRD27 SH3BP4 CEP350 FSIP2 INA CEP112 CRYBG3 ARHGAP21 WNK3 PHLDB2 EXOC4

1.02e-088611381836931259
Pubmed

UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.

UBR4 UBE2A UBE2B

6.11e-083138338182926
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SFMBT1 RPL31 ZNF326 INCENP WDR7 MUC16 BIRC6 DNAH7 SH3BP4 CEP350 PCF11 NEO1 H4C1 UNC5C PWWP3A ARHGAP21

8.81e-087771381635844135
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

EPPK1 ATAD5 ORC3 EIF3E CHD2 TSPYL1 H4C1 HLTF RPA1 SYNCRIP EXOC4

5.46e-073941381127248496
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

1.09e-0620138426694250
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

1.64e-0622138431729367
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL31 ZNF326 INCENP UBR4 EIF3E CHD2 BIRC6 ANKRD27 URB1 IGF2BP2 PDE12 KANSL1 H4C1 HLTF RPA1 TIMM44 PHLDB2 SYNCRIP EXOC4

1.80e-0613531381929467282
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

MYH7 ZNF326 EPPK1 WDR7 EIF3E DNAH2 LAMB1 FNDC3A BCR INA FIG4 HLTF ARHGAP21 EXOC4

1.99e-067541381435906200
Pubmed

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

BRPF3 ZNF326 BCR INA H4C1 CEP112 NEMF RPA1 SYNCRIP

2.11e-06283138928533407
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

2.81e-0625138437451217
Pubmed

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

ANK2 MYOM1 MAP2 ITGA7 PALS2

4.19e-0660138519075228
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

4.51e-0628138425089626
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

RPL31 ZNF326 PPAN CHAF1A TSPYL1 CEP350 ARHGAP5 IGF2BP2 KANSL1 SYNCRIP

6.97e-064171381036537216
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

RPL31 PPAN EPPK1 INCENP UBR4 BIRC6 UBE2R2 SYNCRIP

8.25e-06253138829911972
Pubmed

KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.

EPPK1 UBR4 UBE2A UBE2B

8.88e-0633138425582440
Pubmed

The FgfrL1 receptor is required for development of slow muscle fibers.

MYH3 MYH7 FGFRL1

9.85e-0611138325172430
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RPL31 ZNF326 PPAN INCENP ATAD5 EIF3E TSPYL1 BIRC6 URB1 IGF2BP2 NEMF SYNCRIP EXOC4

1.11e-057591381335915203
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

1.13e-0535138419389355
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ORC3 BCR ANKRD27 SH3BP4 NEMF RAD54B HLTF CRYBG3 ARHGAP21 EXOC4 PLCE1 SORL1

1.18e-056501381238777146
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SFMBT1 ONECUT2 RPL31 ZNF326 CTDSPL2 ATAD5 ORC3 CHAF1A CHD2 TFAP2C PWWP2A URB1 KANSL1 H4C1 HLTF RPA1 SYNCRIP

1.56e-0512941381730804502
Pubmed

The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

UBE2A UBE2B

1.56e-052138215169909
Pubmed

Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.

UBE2A UBE2B

1.56e-052138212556476
Pubmed

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

UBE2A UBE2B

1.56e-05213821717990
Pubmed

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.

UBE2A UBE2B

1.56e-05213821559696
Pubmed

The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.

UBE2A UBE2B

1.56e-052138211885984
Pubmed

Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.

UBE2A UBE2B

1.56e-052138231683936
Pubmed

RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.

UBE2A UBE2B

1.56e-052138228806395
Pubmed

Downregulation of striatin leads to hyperphosphorylation of MAP2, induces depolymerization of microtubules and inhibits proliferation of HEK293T cells.

MAP2 STRN

1.56e-052138225497017
Pubmed

Phosphate transport in osteoblasts from normal and X-linked hypophosphatemic mice.

LAMB1 PHEX

1.56e-05213828082056
Pubmed

Defining the membrane proteome of NK cells.

RPL31 PSEN2 PDGFRA UBR4 EIF3E FNDC3A BCR BIRC6 ANKRD27 CEP350 BPNT2 H4C1 CD37 HLTF SYNCRIP EXOC4

1.70e-0511681381619946888
Pubmed

Functional domains of the FgfrL1 receptor.

MYH3 MYH7 FGFRL1

2.15e-0514138331923383
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

MAP2 WDR7 BCR STRN INA HOMER2

2.80e-05147138616959763
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPRASP1 CACNA2D1 ANK2 WDR7 UBR4 BCR ITIH1 STRN INA RPA1 HOMER2 ARHGAP21 WNK3 PHLDB2

3.11e-059631381428671696
Pubmed

Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.

PRAMEF15 PRAMEF4 ITGA7 PRAMEF11

3.40e-0546138417287250
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

ZNF326 CALD1 KIAA0232 SDCCAG8 BCR DNAH7 CEP350 ARHGAP5 STRN INA TIMM44 ARHGAP21 EXOC4

3.75e-058531381328718761
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

RPL31 ATP6V1E1 ZNF326 PPAN EIF3E LAMB1 TRUB2 SH3BP4 TGFB2 IGF2BP2 TNRC18 H4C1 NEMF RPA1 PHLDB2 SYNCRIP

3.75e-0512471381627684187
Pubmed

Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

PRAMEF15 PRAMEF4 PRAMEF11

3.99e-0517138323565261
Pubmed

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.

PRAMEF15 PRAMEF4 PRAMEF11

3.99e-0517138337781892
Pubmed

Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method.

UBE2R2 UBE2A UBE2B

3.99e-0517138336563856
Pubmed

Stress response silencing by an E3 ligase mutated in neurodegeneration.

UBR4 UBE2A

4.68e-053138238297121
Pubmed

The human RAD18 gene product interacts with HHR6A and HHR6B.

UBE2A UBE2B

4.68e-053138210908344
Pubmed

Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.

MYH3 MYH7

4.68e-05313821694848
Pubmed

Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene.

PDGFRA MAP2

4.68e-05313829510033
Pubmed

Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites.

CHAF1A RPA1

4.68e-053138219059499
Pubmed

Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells.

UBE2A UBE2B

4.68e-053138212509447
Pubmed

Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability.

GAD1 MAP2

4.68e-053138218165320
Pubmed

Identification of three developmentally controlled isoforms of human myosin heavy chains.

MYH3 MYH7

4.68e-05313821691980
Pubmed

Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens.

UBE2A UBE2B

4.68e-053138210884424
Pubmed

The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.

PDGFRA LAMB1

4.68e-053138228783171
Pubmed

Myosin heavy chain gene expression in mouse embryoid bodies. An in vitro developmental study.

MYH3 MYH7

4.68e-05313821939265
Pubmed

RNF168 forms a functional complex with RAD6 during the DNA damage response.

UBE2A UBE2B

4.68e-053138223525009
Pubmed

Multimodal tangential migration of neocortical GABAergic neurons independent of GPI-anchored proteins.

GAD1 MAP2

4.68e-053138214534141
Pubmed

Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKβ signaling cascade.

CARD11 IKBKB

4.68e-053138224345681
Pubmed

Neogenin in Amygdala for Neuronal Activity and Information Processing.

GAD1 NEO1

4.68e-053138230228230
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF15 PRAMEF4 PRAMEF11

4.77e-0518138323894331
Pubmed

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.

PRAMEF15 PRAMEF4 PRAMEF11

4.77e-0518138339181896
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF15 PRAMEF4 PRAMEF11

4.77e-0518138312890732
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF15 PRAMEF4 PRAMEF11

4.77e-0518138329731491
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF15 PRAMEF4 PRAMEF11

4.77e-0518138314675769
Pubmed

A Screen for Epstein-Barr Virus Proteins That Inhibit the DNA Damage Response Reveals a Novel Histone Binding Protein.

H4C1 HLTF RPA1

4.77e-0518138329743367
Pubmed

Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.

UBE2R2 UBE2A UBE2B

5.65e-0519138327425610
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF15 PRAMEF4 PRAMEF11

5.65e-0519138328604677
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CACNA2D1 ZNF326 CALD1 INCENP ORC3 EIF3E LAMB1 TRUB2 CEP350 PCF11 STRN URB1 KANSL1 SYNCRIP EXOC4

5.80e-0511551381520360068
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

GAD1 LAMB1 PDE10A TGFB2 UNC5C PLCE1

6.50e-05171138620201926
Pubmed

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PRAMEF15 PRAMEF4 PRAMEF11

6.63e-0520138316580637
Pubmed

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

PRAMEF15 PRAMEF4 PRAMEF11

6.63e-0520138321425410
Pubmed

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

SFMBT1 SDCCAG8 FTCDNL1 ITIH1 INA

7.67e-05109138523974872
Pubmed

P190A RhoGAP is required for mammary gland development.

ARHGAP5 NEO1

9.33e-054138221945077
Pubmed

Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3.

SFMBT1 H4C1

9.33e-054138217599839
Pubmed

A conserved RAD6-MDM2 ubiquitin ligase machinery targets histone chaperone ASF1A in tumorigenesis.

UBE2A UBE2B

9.33e-054138226336826
Pubmed

Human inter-α-inhibitor is a substrate for factor XIIIa and tissue transglutaminase.

TGM6 ITIH1

9.33e-054138221939789
Pubmed

Neuronal lineage-specific induction of phospholipase Cepsilon expression in the developing mouse brain.

MAP2 PLCE1

9.33e-054138212752375
Pubmed

Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry.

TNRC18 SYNCRIP

9.33e-054138217370265
Pubmed

Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4.

CHAF1A H4C1

9.33e-05413828858152
Pubmed

Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination.

H4C1 RPA1

9.33e-054138234056863
Pubmed

Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy.

LAMB1 ITGA7

9.33e-054138219074617
Pubmed

ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins.

UBE2A UBE2B

9.33e-054138212776193
Pubmed

Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation.

UBE2A UBE2B

9.33e-054138211929833
Pubmed

Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen.

UBE2A RPA1

9.33e-054138230700555
Pubmed

Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen.

CARD11 IKBKB

9.33e-054138219104039
Pubmed

RAD6 promotes homologous recombination repair by activating the autophagy-mediated degradation of heterochromatin protein HP1.

UBE2A UBE2B

9.33e-054138225384975
Pubmed

Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci.

NEO1 UNC5C

9.33e-054138216723533
Pubmed

RAD6 regulates the dosage of p53 by a combination of transcriptional and posttranscriptional mechanisms.

UBE2A UBE2B

9.33e-054138222083959
Pubmed

Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability.

UBE2A UBE2B

9.33e-054138236162503
Pubmed

Role of IκB kinase β in regulating the remodeling of the CARMA1-Bcl10-MALT1 complex.

CARD11 IKBKB

9.33e-054138229649481
Pubmed

Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.

PRAMEF15 PRAMEF4 PRAMEF11

1.02e-0423138319480014
Pubmed

Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system.

GAD1 PDGFRA MAP2

1.02e-0423138319806666
Pubmed

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.

MAP2 UBR4 STRN

1.16e-0424138335179492
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A7 SPATA31A5 OR51G2

1.16e-0424138332212159
Pubmed

Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity.

UBE2R2 UBE2A UBE2B

1.16e-0424138324647965
Pubmed

Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging.

UBE2R2 UBE2A UBE2B

1.32e-0425138317597759
Pubmed

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

PRAMEF15 PRAMEF4 PRAMEF11

1.32e-0425138312620990
Pubmed

Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.

PRAMEF15 PRAMEF4 PRAMEF11

1.49e-0426138318500982
Pubmed

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

UBE2R2 UBE2A UBE2B

1.49e-0426138320061386
Pubmed

Myomesin 3, a novel structural component of the M-band in striated muscle.

MYH7 MYOM1

1.55e-045138218177667
Pubmed

DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis.

UBE2A HLTF

1.55e-045138225023518
Pubmed

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy.

LAMB1 ITGA7

1.55e-045138219416897
Pubmed

Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination.

UBE2A UBE2B

1.55e-045138215359278
Pubmed

Netrin 1 acts as an attractive or as a repulsive cue for distinct migrating neurons during the development of the cerebellar system.

NEO1 UNC5C

1.55e-045138210704383
Cytoband1p36.21

PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 FHAD1 PRAMEF11

3.90e-086313861p36.21
CytobandEnsembl 112 genes in cytogenetic band chr1p36

PRAMEF25 PRAMEF9 UBR4 PRAMEF15 PRAMEF4 FHAD1 PDIK1L PRAMEF27 PRAMEF11

2.32e-046811389chr1p36
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

2.48e-0481382chr9q12
GeneFamilyPRAME family

PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27 PRAMEF11

2.54e-0924976686
GeneFamilyMyosin heavy chains

MYH3 MYH7 MYH16

6.50e-05159731098
GeneFamilyUbiquitin conjugating enzymes E2

BIRC6 UBE2R2 UBE2A UBE2B

6.77e-0541974102
GeneFamilyPWWP domain containing

BRPF3 PWWP2A PWWP3A

2.14e-04229731147
GeneFamilyFibronectin type III domain containing

MYOM1 FNDC3A FNDC1 NEO1 SORL1

1.71e-03160975555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MYOM1 PDGFRA FGFRL1 NEO1 UNC5C

1.75e-03161975593
GeneFamilyCTAGE family

CTAGE6 CTAGE15

2.86e-0315972907
GeneFamilyDyneins, axonemal

DNAH2 DNAH7

3.68e-0317972536
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500

PDGFRA RGN IGF2BP2 TNRC18 HOMER2 WNK3 PHLDB2

9.27e-061231277gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

CACNA2D1 CALD1 PDGFRA ATAD5 MUC16 DNAH7 BRWD3 CEP350 PCF11 TGFB2 NEO1 IGF2BP2 UNC5C WNK3 PHLDB2 PLCE1

3.70e-0583112716gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000

BRPF3 MANBA PDGFRA DNAH7 BRWD3 PCF11 RGN NEO1 IGF2BP2 TNRC18 HOMER2 ARHGAP21 WNK3 PHLDB2 PLCE1 BBOF1

4.03e-0583712716gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

GAD1 MYH3 ZNF326 NPR3 ANK2 CTDSPL2 LAMB1 TFAP2C BRWD3 PCF11 PHEX NEO1 PDE12 CCDC68 HOMER2 SORL1

4.84e-0585012716gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500

BRPF3 PDGFRA DNAH7 RGN NEO1 IGF2BP2 TNRC18 HOMER2 ARHGAP21 WNK3 PHLDB2

5.84e-0543212711gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

GPRASP1 MAP2 MUC16 DNAH7 BRWD3 PCF11 RGN NEO1 IGF2BP2 TNRC18 FIG4 HOMER2 ARHGAP21 WNK3 PLCE1

7.81e-0579112715gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_500

GAD1 MYH3 MYOM1 ADCY8 RGN FNDC1

9.33e-051221276gudmap_developingGonad_P2_epididymis_500_k5
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000

SFMBT1 MYH3 CTDSPL2 LAMB1 TSPYL1 BIRC6 CEP350 KANSL1 SYNCRIP SORL1

9.57e-0537912710gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

CACNA2D1 CALD1 PDGFRA CHAF1A MUC16 DNAH7 BRWD3 CEP350 TGFB2 NEO1 IGF2BP2 UNC5C WNK3 PHLDB2 PLCE1

1.28e-0482712715gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

GAD1 MYH3 ZNF326 NPR3 CTDSPL2 LAMB1 BRWD3 PCF11 PHEX NEO1 PDE12

1.43e-0447812711gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

MYH3 NPR3 MAP2 CTDSPL2 TFAP2C BRWD3 PCF11 TGFB2 PHEX NEO1 CCDC68 ATP11C IKBKB HOMER2 SYNCRIP

1.44e-0483612715gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

CACNA2D1 CALD1 PDGFRA MAP2 ATAD5 LAMB1 MUC16 TGFB2 GREM2 IGF2BP2 UNC5C RAD54B WNK3 PLCE1

2.06e-0476812714gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

SFMBT1 CACNA2D1 CTDSPL2 LAMB1 CEP350 KANSL1 SYNCRIP

2.10e-042011277gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

CACNA2D1 CALD1 PDGFRA ATAD5 LAMB1 MUC16 CEP350 TGFB2 GREM2 IGF2BP2 UNC5C RAD54B WNK3 PLCE1

2.20e-0477312714gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

CACNA2D1 CALD1 PDGFRA MUC16 BRWD3 NEO1 IGF2BP2 UNC5C WNK3 PLCE1

2.33e-0442312710gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_top-relative-expression-ranked_1000

ONECUT2 ABCC3 MYH7 MANBA ANK2 EAF2 TFAP2C CEP350 STRN PDE12 FIG4 CCDC68 SORL1 CYB561

2.42e-0478012714gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000

LAMB1 FNDC3A CHD2 PDE10A BPNT2 KANSL1 PDIK1L SGCE

2.54e-042751278gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#3_top-relative-expression-ranked_1000

CACNA2D1 CTDSPL2 SDCCAG8 LAMB1 KANSL1 SYNCRIP

3.09e-041521276gudmap_developingKidney_e15.5_Proximal Tubules_1000_k3
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

CACNA2D1 CALD1 PDGFRA MAP2 MUC16 TGFB2 GREM2 UNC5C WNK3

3.27e-043611279gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

CACNA2D1 CALD1 PDGFRA MAP2 MUC16 TGFB2 GREM2 UNC5C WNK3

4.15e-043731279gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

SFMBT1 CACNA2D1 CTDSPL2 SDCCAG8 LAMB1 BIRC6 CEP350 KANSL1 SYNCRIP

4.32e-043751279gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CALD1 PDGFRA ATAD5 CHAF1A LAMB1 TGFB2 GREM2 FNDC1

9.16e-081791388ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCellILEUM-non-inflamed-(8)_Fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CALD1 PDGFRA LAMB1 FNDC1 UNC5C CCDC68 SGCE CRYBG3

2.06e-071991388d9d7f36b4b5592b7855448730044c90997b55499
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD1 CALD1 TGFB2 GREM2 UNC5C ATP11C HOMER2

7.83e-071631387bba830a302919c8b33f914a8839877fc21dd28a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 GREM2 UNC5C PLCE1

1.36e-0617713874943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 GREM2 UNC5C PLCE1

1.36e-0617713873f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 CALD1 LAMB1 RGN UNC5C CCDC68 PLCE1

1.41e-061781387185b44700f06ec58b3c09c80520502166c965fd6
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

GAD1 CACNA2D1 ANK2 PDGFRA GREM2 FNDC1 RPA1

1.70e-061831387de08f9ea02b7244d5a8788064631d10f06565337
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 TGFB2 UNC5C PLCE1

1.70e-061831387667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 GREM2 UNC5C PLCE1

2.03e-061881387b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 CALD1 LAMB1 RGN UNC5C CCDC68 PLCE1

2.03e-061881387ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 GREM2 UNC5C PLCE1

2.10e-0618913877fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 GREM2 UNC5C PLCE1

2.10e-06189138706b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA2D1 MYH7 ANK2 CALD1 MYOM1 PDE10A ITGA7

2.18e-061901387918ad5037881212008f9f69d5df5da91fd01422c
ToppCellMesenchymal_cells-Smooth_muscle|World / Lineage and Cell class

CALD1 MYOM1 MAP2 ITGA7 BCR H4C1 PLCE1

2.18e-0619013875aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCelldroplet-Skin-nan-18m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 CACNA2D1 ANK2 PDGFRA H4C1 ENDOU

2.25e-0612213868f675dc341b3f6e22f7e52c34d167d9e37df0982
ToppCelldroplet-Skin-nan-18m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 CACNA2D1 ANK2 PDGFRA H4C1 ENDOU

2.25e-061221386c7e81504e62d132624ec15b7d38dc5b6493a37a4
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 EPPK1 TGFB2 FNDC1 PALS2 PLCE1 SORL1

2.34e-0619213870dc1f46e40346ed0b286e53b106a812441575100
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANK2 CALD1 PDGFRA CHAF1A LAMB1 TGFB2 FNDC1

2.42e-061931387f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

CACNA2D1 ANK2 CALD1 PDGFRA LAMB1 FNDC1 UNC5C

2.50e-06194138703a269f75a481ea54aea8e6444605db8d6df493d
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

CACNA2D1 CALD1 LAMB1 ITGA7 RGN UNC5C PLCE1

2.50e-0619413875e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 GREM2 CCDC68 PHLDB2 PLCE1

2.68e-061961387184104cbea0461dd2757668ab9755948ac7b585a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 GREM2 CCDC68 PHLDB2 PLCE1

2.68e-061961387bebb20dc210576101c317011e3afb59798f5d255
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 GREM2 CCDC68 PHLDB2 PLCE1

2.68e-0619613878114e98923096c54b6834f21550c3061bab6773d
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 CALD1 PDGFRA LAMB1 ITGA7 FNDC1 SGCE

2.96e-0619913870cdbedf09ec72734b86ddab3fec562e066afed92
ToppCellILEUM-inflamed-(8)_Fibroblasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANK2 CALD1 PDGFRA LAMB1 FNDC1 UNC5C CRYBG3

2.96e-0619913873a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 CALD1 PDGFRA LAMB1 FNDC1 SGCE CRYBG3

3.06e-062001387c5d818203bef80ff97c2e0158cf61970673dd258
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

ZNF326 UBE2B H4C1 PDIK1L CFAP45 ATP11C

8.64e-061541386a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD1 CALD1 TGFB2 GREM2 UNC5C HOMER2

1.04e-0515913860dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ANK2 MAP2 FNDC1 CCDC68 PHLDB2 PLCE1

1.15e-051621386ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDR2 BRPF3 MARCHF8 ITGA7 UBE2B MTTP

1.15e-05162138608ee7ae56e4927874515c47adc86dd845bf29a26
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD1 CALD1 TGFB2 UNC5C ATP11C HOMER2

1.19e-0516313868d17f44faf0549fe71a9a45f811f50d767275414
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD1 CALD1 TGFB2 UNC5C ATP11C HOMER2

1.24e-05164138608819970174a3eb4eee8e1e675075828665b845e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPAN ANKRD30B DNAH7 FSIP2 TNRC18 CYB561

1.28e-051651386436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPAN ANKRD30B DNAH7 FSIP2 TNRC18 CYB561

1.28e-051651386242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 UNC5C PLCE1

1.28e-0516513864f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 UNC5C PLCE1

1.28e-051651386cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MROH9 MYH3 MYOM1 DNAH2 DNAH7 BBOF1

1.32e-0516613864b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

MUC16 DNAH7 FHAD1 CFAP45 BBOF1 CYB561

1.37e-05167138626cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PYHIN1 STRN HLTF CARD11 IKBKB SORL1

1.42e-051681386182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSMA8 SH3BP4 STRN CCDC68 CRYBG3 GRAP

1.47e-05169138641ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSMA8 SH3BP4 STRN CCDC68 CRYBG3 GRAP

1.47e-05169138642782c61592742190ab0cba8a94f8bdf9c278f90
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

CACNA2D1 CALD1 LAMB1 ITGA7 RGN UNC5C

1.57e-051711386080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA2D1 MYH7 ANK2 MYOM1 PDE10A ITGA7

1.84e-0517613869df7a124ebafb0087da0cda133a394275d7bed81
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 LAMB1 RGN UNC5C CCDC68 PLCE1

1.90e-051771386452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CALD1 MAP2 LAMB1 ADCY8 TGFB2 RGN

2.03e-05179138656db12467b445f2b8ef92af50779eeab10413eb2
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 CALD1 LAMB1 RGN UNC5C PLCE1

2.16e-051811386451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA2D1 CALD1 PDE10A ITGA7 UNC5C PLCE1

2.16e-05181138633cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

MROH9 DNAH2 DNAH7 FHAD1 CFAP45 BBOF1

2.23e-051821386fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellIIH-Treg-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

MARCHF8 LAMB1 BRWD3 TRUB2 PWWP2A TNRC18

2.23e-0518213865c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 BCR PHLDB2 PLCE1

2.23e-051821386ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 BCR PHLDB2 PLCE1

2.37e-05184138694748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 BCR PHLDB2 PLCE1

2.37e-051841386819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 LAMB1 RGN UNC5C CCDC68 PLCE1

2.52e-051861386888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MAP2 ITGA7 GREM2 UNC5C PLCE1

2.59e-051871386ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 UNC5C PLCE1

2.59e-05187138648bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NPR3 CALD1 MAP2 LAMB1 ITGA7 PLCE1

2.59e-0518713861aebf6fab40b96f2f5feb77a302bb805838fccf3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MAP2 ITGA7 GREM2 UNC5C PLCE1

2.59e-051871386530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA2D1 CALD1 PDGFRA TGFB2 RGN CCDC68

2.59e-051871386c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 UNC5C PLCE1

2.59e-051871386958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ANK2 CALD1 MYOM1 UNC13D ITGA7 PLCE1

2.67e-0518813866d249fe92d51a19da19ec14bb2262d394255d577
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ONECUT2 CALD1 INA PWWP3A CRYBG3 PLCE1

2.67e-051881386e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 CALD1 MYOM1 ITGA7 TGFB2 PLCE1

2.67e-051881386d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANK2 CALD1 PDGFRA TGFB2 FNDC1 PLCE1

2.75e-051891386eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 UNC5C PLCE1

2.75e-051891386fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANK2 CALD1 PDGFRA TGFB2 FNDC1 PLCE1

2.75e-05189138640764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

CALD1 LAMB1 RGN UNC5C CCDC68 PLCE1

2.75e-051891386d7ed96add29f219183c802895fbff519b627f635
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

MYH7 ANK2 CALD1 MYOM1 FNDC3A PHLDB2

2.84e-05190138693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 PDGFRA LAMB1 GREM2 FNDC1 SGCE

2.84e-051901386bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCelldroplet-Tongue-nan-3m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 TGM6 TGFB2 UNC5C CCDC68 HOMER2

2.84e-051901386251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 PDGFRA LAMB1 GREM2 FNDC1 SGCE

2.84e-051901386e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 PDGFRA LAMB1 GREM2 FNDC1 SGCE

2.84e-051901386ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

CACNA2D1 ANK2 CALD1 PDGFRA LAMB1 UNC5C

2.84e-0519013863a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 PDGFRA MAP2 LAMB1 ITGA7 FNDC1

2.92e-051911386b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 LAMB1 RGN CCDC68 SGCE PLCE1

2.92e-0519113861626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA2D1 ANK2 CALD1 ITGA7 GREM2 FNDC1

2.92e-0519113867853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 CCDC68 PHLDB2 PLCE1

2.92e-05191138696ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MROH9 DNAH2 MUC16 DNAH7 FHAD1 BBOF1

2.92e-051911386e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MROH9 DNAH2 MUC16 DNAH7 FHAD1 BBOF1

2.92e-0519113869d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 LAMB1 RGN CCDC68 SGCE PLCE1

2.92e-051911386716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MROH9 DNAH2 MUC16 DNAH7 FHAD1 BBOF1

2.92e-0519113861c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellMatrixFB-Fibroblast-D_(Pericyte)|MatrixFB / shred on cell class and cell subclass (v4)

CALD1 MYOM1 ITGA7 ADCY8 TGFB2 CCDC68

3.01e-051921386630444302511f511ec6976bc045a3b4b9d8d4547
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 ITGA7 GREM2 UNC5C PLCE1

3.01e-051921386bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 ITGA7 GREM2 UNC5C PLCE1

3.01e-051921386b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

DNAH2 MUC16 DNAH7 FHAD1 CFAP45 BBOF1

3.01e-0519213869cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SFMBT1 GPRASP1 RPL31 EIF3E UBE2B SORL1

3.10e-0519313864e78ddc96d8e403a21c4a303b1f26512d2ac91e8
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CALD1 PDGFRA LAMB1 PHEX UNC5C PHLDB2

3.10e-051931386b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NPR3 CALD1 MAP2 LAMB1 ITGA7 PLCE1

3.10e-051931386ba6eb29478d16589172f48f9992e5116328c81d6
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 PDGFRA LAMB1 PHEX UNC5C PHLDB2

3.19e-051941386e93de9428c986b8943fc169258847c650cfab0e5
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 PDGFRA LAMB1 GREM2 FNDC1 CCDC68

3.19e-0519413868fae8061b350336299aa81f378e07deadbd55123
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCC3 CACNA2D1 CALD1 LAMB1 ITGA7 SGCE

3.19e-051941386f44394c8a6f86483063f2f5722f003a8a0a70254
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 GREM2 PHLDB2 PLCE1

3.19e-051941386bf34737ae2dc218f890fbb9201c308b324415749
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 CCDC68 PHLDB2 PLCE1

3.19e-0519413863bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 PDGFRA LAMB1 GREM2 FNDC1 CCDC68

3.19e-0519413864d7d24390fdb379f943ddcc70a63f23955e10163
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 GREM2 PHLDB2 PLCE1

3.19e-051941386b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALD1 MYOM1 MAP2 ITGA7 FNDC1 UNC5C

3.19e-051941386ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 GREM2 PHLDB2 PLCE1

3.19e-0519413864ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MYOM1 ITGA7 CCDC68 PHLDB2 PLCE1

3.19e-051941386fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CALD1 PDGFRA TGFB2 GREM2 FNDC1 PHLDB2

3.28e-0519513862514c1f23424b5fc664d326d31ffd22bafe74ef8
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ANK2 CALD1 PDGFRA LAMB1 RGN CCDC68

3.28e-0519513862b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCellE17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANK2 CALD1 PDGFRA GREM2 FNDC1 RPA1

3.28e-0519513861daddd801bd4596fffbdb822fc326d5127c96004
ComputationalMuscle genes.

MYH3 MYH7 CALD1 MYOM1

1.41e-0437784MODULE_512
ComputationalGenes in the cancer module 387.

MYH3 MYH7 CALD1 MYOM1

4.24e-0449784MODULE_387
ComputationalGenes in the cancer module 201.

MYH3 MYH7 CALD1 MYOM1

4.59e-0450784MODULE_201
ComputationalGenes in the cancer module 329.

MYH3 MYH7 CALD1 MYOM1

4.95e-0451784MODULE_329
DrugCocaine

GPRASP1 ABCC3 GAD1 MYH7 CYP2C8 CALD1 MYOM1 MAP2 ATAD5 UBR4 EIF3E LAMB1 TSPYL1 ADCY8 TGFB2 ARHGAP5 FNDC1 NEO1 INA IKBKB HOMER2 WNK3 SORL1

2.43e-06131413423ctd:D003042
Diseaseobsolete_red blood cell distribution width

MARCHF8 KIAA0232 CHAF1A FTCDNL1 UNC13D BIRC6 ANKRD27 STRN NEO1 IGF2BP2 KANSL1 FIG4 C1orf105 ATP11C ARHGAP21 WNK3 BBOF1

4.04e-05134712217EFO_0005192
DiseaseCongenital abnormality of respiratory system

PDGFRA TGFB2

5.07e-0531222C0035238
DiseaseBMI-adjusted waist circumference, physical activity measurement

NPR3 ATAD5 ITIH1 TGFB2 H4C1

1.63e-041231225EFO_0007789, EFO_0008002
Diseasebipolar disorder, schizophrenia, schizoaffective disorder

SDCCAG8 ITIH1

2.52e-0461222EFO_0005411, MONDO_0004985, MONDO_0005090
Diseasetestosterone measurement

CACNA2D1 RPL31 CYP2C8 MANBA ANK2 DNAH2 FGFRL1 UNC13D BIRC6 TGFB2 FHAD1 URB1 CEP112 MYH16 ARHGAP21

2.55e-04127512215EFO_0004908
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH3 MYH7

7.47e-04101222DOID:0080326 (implicated_via_orthology)
Diseaseresponse to antineoplastic agent

CACNA2D1 UBR4 ADCY8 TRMT44

7.73e-04991224GO_0097327
Diseasehepatocyte growth factor measurement

CACNA2D1 CALD1 BPNT2

8.07e-04441223EFO_0006903
DiseaseAntihypertensive use measurement

NPR3 PDE10A ADCY8 PHLDB2 PLCE1 CYB561

8.40e-042651226EFO_0009927
Diseasedistal myopathy (implicated_via_orthology)

MYH3 MYH7

1.09e-03121222DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH3 MYH7

1.09e-03121222DOID:2106 (implicated_via_orthology)
Diseasewhite matter microstructure measurement

CACNA2D1 EPPK1 UNC13D STRN KANSL1 CARD11 ARHGAP21

1.22e-033901227EFO_0005674
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH3 MYH7

1.28e-03131222DOID:397 (implicated_via_orthology)
Diseaseleukemia (is_implicated_in)

PDGFRA BCR

1.28e-03131222DOID:1240 (is_implicated_in)
Diseasehealth study participation

SFMBT1 SDCCAG8 BIRC6 TEX29 EXOC4

1.33e-031951225EFO_0010130
Diseasecortical surface area measurement

CACNA2D1 MAP2 CHAF1A FGFRL1 BCR DNAH7 STRN NEO1 KANSL1 INA CEP112 UNC5C ARHGAP21 PLCE1

1.35e-03134512214EFO_0010736
Diseasediastolic blood pressure, alcohol drinking

NPR3 SDCCAG8 PDE10A CYB561

1.48e-031181224EFO_0004329, EFO_0006336
Diseasealcohol dependence measurement

BPNT2 UNC5C ARHGAP21

1.55e-03551223EFO_0007835
DiseaseAlzheimer's disease (implicated_via_orthology)

ANK2 PSEN2 MAP2

1.71e-03571223DOID:10652 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH3 MYH7

1.72e-03151222DOID:0050646 (implicated_via_orthology)
DiseaseFEV/FEC ratio

CALD1 MAP2 KIAA0232 EIF3E TFAP2C ADCY8 TGFB2 GREM2 IGF2BP2 UBE2A HOMER2 PHLDB2 SORL1

1.74e-03122812213EFO_0004713
Diseasemean reticulocyte volume

MARCHF8 CHAF1A DNAH2 CEP350 IGF2BP2 KANSL1 C1orf105 RPA1 ARHGAP21 BBOF1

1.81e-0379912210EFO_0010701
Diseasevital capacity

MROH9 MAP2 ATAD5 UNC13D ADCY8 TGFB2 IGF2BP2 KANSL1 H4C1 PDIK1L MTTP HOMER2 PLCE1

1.84e-03123612213EFO_0004312
Diseasesyndromic intellectual disability (implicated_via_orthology)

UBE2A UBE2B

1.96e-03161222DOID:0050888 (implicated_via_orthology)
Diseasepreeclampsia, hypertension, pregnancy-induced

NPR3 PLCE1

1.96e-03161222EFO_0000668, MONDO_0024664
Diseaseanxiety

PSEN2 ITIH1 INA H4C1 CYB561

2.39e-032231225EFO_0005230
DiseaseCongenital Fiber Type Disproportion

MYH7 ITGA7

2.48e-03181222C0546264
Diseaseulcerative colitis

SFMBT1 CACNA2D1 UBR4 LAMB1 ADCY8 TNRC18

2.75e-033351226EFO_0000729
Diseasebipolar disorder

MAP2 FTCDNL1 PDE10A ITIH1 H4C1 PALS2 RPA1 HOMER2

2.80e-035771228MONDO_0004985
Diseasecongenital heart disease (implicated_via_orthology)

UBE2R2 UBE2A UBE2B

2.96e-03691223DOID:1682 (implicated_via_orthology)
Diseasecardiomyopathy (implicated_via_orthology)

MYH3 MYH7 ITGA7

3.21e-03711223DOID:0050700 (implicated_via_orthology)
DiseasePrecursor B-cell lymphoblastic leukemia

PDGFRA BCR

3.38e-03211222C1292769
Diseasecognitive function measurement, self reported educational attainment

SFMBT1 GAD1 BIRC6 ITIH1 KANSL1 EXOC4

3.65e-033551226EFO_0004784, EFO_0008354
DiseaseSchizophrenia

GAD1 PSEN2 SDCCAG8 ITIH1 IGF2BP2 PDIK1L UNC5C CCDC68 HOMER2 WNK3

3.71e-0388312210C0036341
Diseaseintellectual disability (implicated_via_orthology)

ANK2 UBR4 KANSL1

3.75e-03751223DOID:1059 (implicated_via_orthology)
DiseaseBipolar Disorder

GAD1 PSEN2 MAP2 PDE10A BCR ITIH1 ADCY8

3.76e-034771227C0005586
Diseaseplatelet reactivity measurement, response to clopidogrel

PDE10A PLCE1

4.05e-03231222EFO_0004985, GO_1903493
DiseaseCraniofacial Abnormalities

PDGFRA TGFB2 PHEX KANSL1

4.07e-031561224C0376634

Protein segments in the cluster

PeptideGeneStartEntry
KTIRYVRSRTKHDVD

ADCY8

491

P40145
FVESSTSVLRYKKQV

ATAD5

151

Q96QE3
TVTKRASQYREQLKV

ANKRD30B

1136

Q9BXX2
STSKYKVTVAEVQRR

TFAP2C

236

Q92754
TYTNRLRSKRENVKT

BIRC6

4446

Q9NR09
QTQRTARAKRKYSEV

CTDSPL2

16

Q05D32
EKLSRATEQLETYRK

CTAGE6

421

Q86UF2
EKLSRATEQLETYRK

CTAGE15

421

A4D2H0
ATYRKTAEEVIKNTE

CRYBG3

1786

Q68DQ2
FVNKAKTRVYRDTAE

BCR

941

P11274
VVVSIKEDKYFQTSR

ANKRD20A4P

806

Q4UJ75
AARTNEYKIIRTNEK

INA

81

Q16352
LVDFYRTTTIAKKRQ

GRAP

131

Q13588
YRSKQHETEETIRKL

CEP112

301

Q8N8E3
NVALTRSYIREKVKE

CYP2C8

236

P10632
RKTSIRKSVQVAYDR

BRPF3

1171

Q9ULD4
ISEYKSAIQSQKRRR

BRWD3

1431

Q6RI45
IEETEYVKKIRTTLQ

CCDC68

31

Q9H2F9
SRLKRLISENSVYEK

CHAF1A

796

Q13111
VYRVFRNEAKRTTKV

CYB561

71

P49447
IVFSYQRRTKKELAS

ANXA2P2

71

A6NMY6
IKYRDTSRILAKSNE

BBOF1

51

Q8ND07
KKYRITIERRTQQEE

NPR3

506

P17342
TGTIEEKIYQRQISK

RAD54B

771

Q9Y620
ESNIVAVERVKEYSK

ABCC3

1251

O15438
RKSERRIKELTYQTE

MYH7

1841

P12883
RKIIRRYVSSEGTEK

ANK2

3901

Q01484
VAETDRKEYVTVKIR

ANKRD27

906

Q96NW4
LERKEVSKYSDIQRS

PDGFRA

746

P16234
VTTRRRKKEGEYNVQ

MUC16

14476

Q8WXI7
VIRDAVTYTEHAKRK

H4C1

66

P62805
EVQTVTSIQKARKVY

NEMF

511

O60524
QAIQSFEKKVRVIYT

IKBKB

596

O14920
KYSLVAKQESVVRRA

INCENP

321

Q9NQS7
SKVTFQLTYEEVLKR

ITIH1

156

P19827
RSLKTDIEESKYRQR

HOMER2

306

Q9NSB8
KTERKTERFSYSRNQ

FSIP2

2206

Q5CZC0
NKARYRTKAVSSEVD

CFAP45

21

Q9UL16
NYVRKTFDRSTKVLD

GAD1

126

Q99259
TYRQREKQGTKVADS

SYNCRIP

101

O60506
NATYKVDVIQRTRSK

FGFRL1

231

Q8N441
RKSKLETTYRNRQDT

KIAA0232

416

Q92628
VYSVKTKQIRDRVTH

OR51G2

296

Q8NGK0
YRESKTRVKNRVTVV

MTTP

771

P55157
VSAYVAKSRKTLLVE

PDE10A

151

Q9Y233
TKKVTEDALIRTVSY

PDE12

286

Q6L8Q7
ITKEEIQSISEKIYR

ENDOU

136

P21128
KEVAQRITAELKRYS

ONECUT2

336

O95948
VSRYVSPEQKKEIVT

PRAMEF15

246

P0DUQ1
VAATTRVEKLQYKEI

KANSL1

871

Q7Z3B3
AISARVYRSKTKEKE

MARCHF8

16

Q5T0T0
YRETVDSVERKVSEI

LAMB1

1216

P07942
VDYSVSKKLRSRKIQ

IGF2BP2

71

Q9Y6M1
RFTVTKVRKYISVDA

MROH9

151

Q5TGP6
SQEALVVTERKYLKS

GREM2

56

Q9H772
VKARSSYNEKTPRIV

BPNT2

226

Q9NX62
YRQNRTEKDVSRKVT

PCF11

1366

O94913
LKKTVDESARIQRAY

PALS2

486

Q9NZW5
VKVETYNDESRIKAT

RPA1

576

P27694
YIKSTSRVVQRNKEK

EXOC4

201

Q96A65
YEKDVEQLRRSKVSI

FHAD1

1311

B1AJZ9
KTRVEGSSKIQYRKE

EAF2

111

Q96CJ1
KTFRTLVKSQDERYI

CACNA2D1

586

P54289
IKAKLEETITQARYS

CACNA2D1

631

P54289
QYQIVERVIAVKTSK

CHD2

376

O14647
TKQEIDEQRTKYRSL

CDR2

436

Q01850
NAETKYRVLKIDRTE

FIG4

31

Q92562
EDLAYTVKNLRRSTK

FNDC3A

521

Q9Y2H6
EKQKKVVASRQYTVR

FNDC1

286

Q4ZHG4
KLIEEIQYTSIKTIR

DNAH7

531

Q8WXX0
IVNRKTTIYEIQDKT

PYHIN1

336

Q6K0P9
LDIESTSKRVYKQAV

CEP350

2961

Q5VT06
YLTTAVITNKDVRKR

EIF3E

256

P60228
SVTAEVAYQIKRLKS

MANBA

431

O00462
YKRSVITIATSVDKL

FTCDNL1

56

E5RQL4
VKDKLRAIVVTLSYS

ITGA7

626

Q13683
KRRKTAVQYIESSDS

HLTF

386

Q14527
SIIESRVEKRTKGVY

DNAH2

2456

Q9P225
KITREKLDQVATAVY

IZUMO4

71

Q1ZYL8
RRQKTETIIYSREKN

CARD11

1016

Q9BXL7
ERSLRDVVEKTIQKY

CD37

116

P11049
SFRRYVEKQASEKQV

ORC3

371

Q9UBD5
SRSRFRSKKEVYVES

GPRASP1

281

Q5JY77
SVRQRDKKASVLYIE

PWWP3A

431

Q2TAK8
SKYEDKKRRNESVTT

PWWP2A

346

Q96N64
AVAVKDLIRKTDRSY

SORL1

1966

Q92673
YTDTILDVKSKRVRA

STRN

171

O43815
SREASVDEKRTQYIK

TRMT44

511

Q8IYL2
TNYEVKASEQAKVVR

SH3BP4

546

Q9P0V3
IYNRAVKNTRKVAVS

LIPI

121

Q6XZB0
KNDREVKKSVYTGTR

PLCE1

331

Q9P212
KTRSEIAQLSQEKRY

SDCCAG8

616

Q86SQ7
VVYEAVIRKTSARVA

PDIK1L

21

Q8N165
TAESQKTVKNRSRVY

SPATA31A7

1186

Q8IWB4
KETYVKLLSAERAVT

EPPK1

1636

P58107
IRYRKASRKSDVTET

NEO1

671

Q92859
VSRYVSPEQKKEIVT

PRAMEF25

246

A6NGN4
ERATRAKTEKQRSDY

MYH3

1126

P11055
VSRYVSPEQKKEIVT

PRAMEF27

246

A3QJZ7
QISNRRSVYKLEKEE

RGN

186

Q15493
AYKTQRQLVVTATDK

ARHGAP5

261

Q13017
VAEYQRNIVSRKEKI

PHLDB2

751

Q86SQ0
TLVTKRDSKGVYDVR

URB1

181

O60287
VDKTKQVSTYQEVIR

SGCE

276

O43556
TTEKEEKSESRQERY

CALD1

146

Q05682
LTEAYKTLKERQRSS

C1orf105

156

O95561
STVYIIENAKRVRKE

ATP11C

126

Q8NB49
TQRYIDSKVVKTRAE

TGFB2

181

P61812
VSRYVSPEQKKEIVT

PRAMEF4

246

O60810
EYTDSESEVKVRKRS

TNRC18

1911

O15417
KKGRSAINEVVTREY

RPL31

11

P62899
TAESQKTVKNRSRVY

SPATA31A5

1186

Q5VU36
QVKKYSLVRDVVSSL

PPAN

111

Q9NQ55
FRNKLIVKEYEVRSS

TSPYL1

331

Q9H0U9
VSRYVSPEQKKEIVT

PRAMEF9

246

P0DUQ2
RPSTDVKSQTREKVY

ZNF556

356

Q9HAH1
QENKREYEKRVSAIV

UBE2A

131

P49459
RRDTEAIQKAKILYS

PHEX

126

P78562
VSRYVSPEQKKEIVT

PRAMEF11

246

O60813
VVVATIKSVRFYTEK

PSEN2

101

P49810
STVSRDEVRRKKAVY

MAP2

1451

P11137
RIKTSLTSQVDDYKR

MYH16

466

Q9H6N6
VLQEARRKYKTIESE

TIMM44

96

O43615
RRKYKTIESETVRTS

TIMM44

101

O43615
KSYRATVEIVKTADR

SFMBT1

581

Q9UHJ3
RLSKVVKDTTRYQVL

ATP6V1E1

101

P36543
YAEIIRKQVSATKAE

UBE2R2

161

Q712K3
TIIYRVIQESRKEKA

TEX29

76

Q8N6K0
RLVEKTTYDHVTREK

TRUB2

146

O95900
TVEYITRFIATLKQK

PSMA8

111

Q8TAA3
RSAKTVREFLEKNYT

PSMA8

171

Q8TAA3
KVDTRYTTTQQVVKL

UBR4

3551

Q5T4S7
IDISYSETKRKNVFR

ARHGAP21

996

Q5T5U3
KKISTSYEERRKQAT

WDR7

1111

Q9Y4E6
AKRKSTTATVIVYVN

UNC5C

246

O95185
VKASYRASEQKLRVE

UNC13D

916

Q70J99
EDESRERVYSNTKKI

TGM6

406

O95932
QENKREYEKRVSAIV

UBE2B

131

P63146
ELYERLRSIKDSKTQ

WNK3

1561

Q9BYP7
AYKEQIKRESVLTAT

ZNF326

436

Q5BKZ1
DVRSTVSHYQREKKR

MYOM1

21

P52179