Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

1.09e-1526498GO:0004435
GeneOntologyMolecularFunctionphospholipase C activity

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

2.98e-1529498GO:0004629
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

8.85e-1197498GO:0008081
GeneOntologyMolecularFunctionphospholipase activity

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

3.27e-10114498GO:0004620
GeneOntologyMolecularFunctionlipase activity

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

1.51e-09138498GO:0016298
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1 DNAJC6

3.56e-07386499GO:0042578
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PLCD3 PLCZ1 PLCH2 ASTE1 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1 DNAJC6

2.16e-058074910GO:0016788
GeneOntologyMolecularFunctioncalcium ion binding

PLCZ1 EYS PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLS1

4.36e-04749498GO:0005509
GeneOntologyMolecularFunctioncytidine deaminase activity

APOBEC3D APOBEC3B

4.52e-0413492GO:0004126
GeneOntologyMolecularFunctionstructural constituent of eye lens

CRYGC CRYGD

1.57e-0324492GO:0005212
GeneOntologyMolecularFunctionmannosyltransferase activity

DPY19L2 DPY19L2P2

2.14e-0328492GO:0000030
GeneOntologyMolecularFunctionchemorepellent activity

EPHA7 SEMA4C

2.30e-0329492GO:0045499
GeneOntologyMolecularFunctiondeaminase activity

APOBEC3D APOBEC3B

3.15e-0334492GO:0019239
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

APOBEC3D APOBEC3B

3.52e-0336492GO:0016814
GeneOntologyBiologicalProcesslipid catabolic process

PLCD3 PLCZ1 SPHK1 PLCH2 NAGLU PLCB1 PLCD4 PLCB3 PLCB4

2.07e-07382489GO:0016042
GeneOntologyBiologicalProcessphosphatidylinositol-mediated signaling

PLCH2 PLCB1 PLCB3 PLCB4

2.65e-0724484GO:0048015
GeneOntologyBiologicalProcessphosphatidylinositol metabolic process

PLCH2 SOCS4 PLCB1 PLCD4 PLCB3 PLCB4

2.64e-06170486GO:0046488
GeneOntologyBiologicalProcessphosphatidylinositol catabolic process

PLCB1 PLCB3

3.17e-054482GO:0031161
GeneOntologyBiologicalProcessregulation of defense response to virus

APOBEC3D ITCH TREML4 APOBEC3B

5.69e-0590484GO:0050688
GeneOntologyBiologicalProcessprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

DPY19L2 DPY19L2P2

7.91e-056482GO:0018406
GeneOntologyBiologicalProcesspeptidyl-tryptophan modification

DPY19L2 DPY19L2P2

7.91e-056482GO:0018211
GeneOntologyBiologicalProcessprotein C-linked glycosylation

DPY19L2 DPY19L2P2

7.91e-056482GO:0018103
GeneOntologyBiologicalProcessprotein C-linked glycosylation via tryptophan

DPY19L2 DPY19L2P2

7.91e-056482GO:0018317
GeneOntologyBiologicalProcessclearance of foreign intracellular DNA

APOBEC3D APOBEC3B

7.91e-056482GO:0044355
GeneOntologyBiologicalProcessclearance of foreign intracellular nucleic acids

APOBEC3D APOBEC3B

7.91e-056482GO:0099046
GeneOntologyBiologicalProcessglycerophospholipid metabolic process

PLCH2 SOCS4 PLCB1 PLCD4 PLCB3 PLCB4

9.43e-05320486GO:0006650
GeneOntologyBiologicalProcessDNA cytosine deamination

APOBEC3D APOBEC3B

2.36e-0410482GO:0070383
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

PLCH2 PLCB1 PLCB3 PLCB4

2.58e-04133484GO:0007200
GeneOntologyBiologicalProcessmaintenance of location in cell

PLCH2 NAGLU PLCB1 PLCB3 PLCB4

3.31e-04259485GO:0051651
GeneOntologyBiologicalProcesscytidine to uridine editing

APOBEC3D APOBEC3B

3.45e-0412482GO:0016554
GeneOntologyBiologicalProcessphospholipid metabolic process

PLCH2 SOCS4 PLCB1 PLCD4 PLCB3 PLCB4

3.60e-04410486GO:0006644
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

PLCH2 PLCB1 PLCB3 PLCB4

3.68e-04146484GO:0051209
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

PLCH2 PLCB1 PLCB3 PLCB4

3.78e-04147484GO:0051283
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

PLCH2 PLCB1 PLCB3 PLCB4

3.98e-04149484GO:0051282
GeneOntologyBiologicalProcesssequestering of calcium ion

PLCH2 PLCB1 PLCB3 PLCB4

4.39e-04153484GO:0051208
GeneOntologyBiologicalProcessglycerolipid metabolic process

PLCH2 SOCS4 PLCB1 PLCD4 PLCB3 PLCB4

4.58e-04429486GO:0046486
GeneOntologyBiologicalProcessglycoprotein metabolic process

GCNT7 DPY19L2 NAGLU PLCB1 DPY19L2P2 ATP4B

4.64e-04430486GO:0009100
GeneOntologyBiologicalProcesscytidine metabolic process

APOBEC3D APOBEC3B

4.74e-0414482GO:0046087
GeneOntologyBiologicalProcesscytidine catabolic process

APOBEC3D APOBEC3B

4.74e-0414482GO:0006216
GeneOntologyBiologicalProcesscytidine deamination

APOBEC3D APOBEC3B

4.74e-0414482GO:0009972
GeneOntologyBiologicalProcessDNA deamination

APOBEC3D APOBEC3B

4.74e-0414482GO:0045006
GeneOntologyBiologicalProcessegg activation

PLCZ1 PLCB1

5.46e-0415482GO:0007343
GeneOntologyBiologicalProcessnegative regulation of single stranded viral RNA replication via double stranded DNA intermediate

APOBEC3D APOBEC3B

6.23e-0416482GO:0045869
GeneOntologyBiologicalProcesspyrimidine ribonucleoside metabolic process

APOBEC3D APOBEC3B

6.23e-0416482GO:0046131
GeneOntologyBiologicalProcesspyrimidine ribonucleoside catabolic process

APOBEC3D APOBEC3B

6.23e-0416482GO:0046133
GeneOntologyBiologicalProcessinositol trisphosphate metabolic process

PLCB1 PLCB3

7.05e-0417482GO:0032957
GeneOntologyBiologicalProcesspyrimidine nucleoside catabolic process

APOBEC3D APOBEC3B

7.92e-0418482GO:0046135
GeneOntologyBiologicalProcessregulation of single stranded viral RNA replication via double stranded DNA intermediate

APOBEC3D APOBEC3B

8.84e-0419482GO:0045091
GeneOntologyBiologicalProcessbase conversion or substitution editing

APOBEC3D APOBEC3B

8.84e-0419482GO:0016553
GeneOntologyBiologicalProcesssingle stranded viral RNA replication via double stranded DNA intermediate

APOBEC3D APOBEC3B

9.81e-0420482GO:0039692
GeneOntologyBiologicalProcesstube morphogenesis

PLCD3 SPHK1 NAGLU EMILIN2 FLVCR2 PLXND1 KDM6A EPHA7 SEMA4C

1.01e-031125489GO:0035239
DomainPLipase_C_Pinositol-sp_Y

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.45e-1815478IPR001711
DomainEF-hand_like

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.45e-1815478PF09279
DomainPIPLC_Y_DOMAIN

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.45e-1815478PS50008
DomainPI-PLC_fam

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.45e-1815478IPR001192
DomainPLC_EF-hand-like

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.45e-1815478IPR015359
DomainPI-PLC-Y

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.45e-1815478PF00387
DomainPLCYc

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.45e-1815478SM00149
DomainPI-PLC-X

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

3.68e-1718478PF00388
DomainPLCXc

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

3.68e-1718478SM00148
DomainPIPLC_X_DOMAIN

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

6.35e-1719478PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

6.35e-1719478IPR000909
Domain-

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

8.99e-16254783.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

8.99e-1625478IPR017946
DomainC2_dom

PLCD3 PLCZ1 ITCH PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1 DNAJC6

8.09e-121644710IPR000008
DomainC2

PLCD3 PLCZ1 ITCH PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

3.38e-11131479PF00168
DomainC2

PLCD3 PLCZ1 ITCH PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

5.07e-11137479SM00239
DomainC2

PLCD3 PLCZ1 ITCH PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

7.01e-11142479PS50004
Domain-

PLCD3 PLCZ1 ITCH PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

1.02e-101484792.60.40.150
DomainPLC-beta_CS

PLCB1 PLCB3 PLCB4

1.49e-083473IPR009535
DomainDUF1154

PLCB1 PLCB3 PLCB4

1.49e-083473PF06631
Domain-

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1 PLS1

1.52e-082614791.10.238.10
DomainEF-hand-dom_pair

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1 PLS1

3.44e-08287479IPR011992
DomainPLC-beta

PLCB1 PLCB3 PLCB4

5.96e-084473IPR016280
DomainPH_dom-like

PLCD3 PLCH2 SNTG1 PLCB1 PLEKHA2 PLCD4 PLCB3 PLCB4 PLCL1 TECPR1

8.35e-084264710IPR011993
Domain-

PLCD3 PLCH2 SNTG1 PLEKHA2 PLCD4 PLCB3 PLCB4 PLCL1 TECPR1

4.75e-073914792.30.29.30
DomainPH

PLCD3 PLCH2 SNTG1 PLEKHA2 PLCD4 PLCL1 TECPR1

5.67e-06278477SM00233
DomainPH_DOMAIN

PLCD3 PLCH2 SNTG1 PLEKHA2 PLCD4 PLCL1 TECPR1

5.81e-06279477PS50003
DomainPH_domain

PLCD3 PLCH2 SNTG1 PLEKHA2 PLCD4 PLCL1 TECPR1

5.95e-06280477IPR001849
DomainPLC-beta_C

PLCB1 PLCB3

1.86e-053472IPR014815
DomainPLC-beta_C

PLCB1 PLCB3

1.86e-053472PF08703
DomainPH_12

PLCH2 PLCL1

9.24e-056472PF16457
DomainEF_HAND_1

PLCD3 PLCZ1 PLCH2 PLCD4 PLS1

1.56e-04204475PS00018
DomainEF_HAND_2

PLCD3 PLCZ1 PLCH2 PLCD4 PLS1

2.78e-04231475PS50222
DomainAPOBEC_N

APOBEC3D APOBEC3B

4.03e-0412472PF08210
DomainAPOBEC_N

APOBEC3D APOBEC3B

4.03e-0412472IPR013158
DomainAPOBEC/CMP_deaminase_Zn-bd

APOBEC3D APOBEC3B

5.53e-0414472IPR016192
DomainCRYSTALLIN_BETA_GAMMA

CRYGC CRYGD

6.37e-0415472PS50915
DomainCrystall

CRYGC CRYGD

6.37e-0415472PF00030
DomainBeta/gamma_crystallin

CRYGC CRYGD

6.37e-0415472IPR001064
DomainXTALbg

CRYGC CRYGD

6.37e-0415472SM00247
DomainCytidine_deaminase-like

APOBEC3D APOBEC3B

8.23e-0417472IPR016193
DomainCYT_DCMP_DEAMINASES_1

APOBEC3D APOBEC3B

8.23e-0417472PS00903
DomainCMP_dCMP_Zn-bd

APOBEC3D APOBEC3B

8.23e-0417472IPR002125
DomainG_crystallin-rel

CRYGC CRYGD

9.24e-0418472IPR011024
DomainEF_Hand_1_Ca_BS

PLCD3 PLCH2 PLCD4 PLS1

9.70e-04175474IPR018247
DomainEF_hand_dom

PLCZ1 PLCH2 PLCD4 PLS1

2.72e-03232474IPR002048
DomainSema

PLXND1 SEMA4C

2.75e-0331472SM00630
DomainSemap_dom

PLXND1 SEMA4C

2.75e-0331472IPR001627
DomainSema

PLXND1 SEMA4C

2.75e-0331472PF01403
DomainSEMA

PLXND1 SEMA4C

2.75e-0331472PS51004
DomainPSI

PLXND1 SEMA4C

2.93e-0332472PF01437
DomainJMJC

HSPBAP1 KDM6A

2.93e-0332472PS51184
DomainPlexin_repeat

PLXND1 SEMA4C

2.93e-0332472IPR002165
DomainJmjC_dom

HSPBAP1 KDM6A

2.93e-0332472IPR003347
DomainJmjC

HSPBAP1 KDM6A

3.11e-0333472SM00558
DomainPSI

PLXND1 SEMA4C

5.48e-0344472IPR016201
PathwayREACTOME_SYNTHESIS_OF_IP3_AND_IP4_IN_THE_CYTOSOL

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4

2.98e-1326377M27053
PathwayREACTOME_SYNTHESIS_OF_IP3_AND_IP4_IN_THE_CYTOSOL

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4

5.35e-1328377MM14711
PathwayREACTOME_INOSITOL_PHOSPHATE_METABOLISM

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4

3.20e-1148377MM14589
PathwayREACTOME_INOSITOL_PHOSPHATE_METABOLISM

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4

3.20e-1148377M26964
PathwayWP_PHOSPHOINOSITIDES_METABOLISM

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4

3.73e-1149377M40046
PathwayWP_GPR40_PATHWAY

PLCD3 PLCZ1 PLCB1 PLCB3 PLCL1

2.77e-1015375M39526
PathwayKEGG_INOSITOL_PHOSPHATE_METABOLISM

PLCD3 PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.04e-0954376M3896
PathwayWP_RESISTIN_AS_A_REGULATOR_OF_INFLAMMATION

PLCD3 PLCB1 PLCD4 PLCB3 PLCB4

2.12e-0833375M39745
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

PLCD3 PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

4.09e-0876376M9052
PathwayWP_PHOSPHATIDYL_INOSITOL_PHOSPHATE_PATHWAY

PLCD3 PLCB1 PLCD4 PLCB3 PLCB4

1.19e-0746375M48317
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

3.31e-076373M47548
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

PLCD3 PLCZ1 SPHK1 PLCB1 PLCD4 PLCB3 PLCB4

3.40e-07178377M2890
PathwayKEGG_MEDICUS_REFERENCE_CASR_PTH_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

5.78e-077373M47505
PathwayKEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

1.97e-0610373M47644
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

1.97e-0610373M47661
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

2.71e-0611373M49033
PathwayKEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

2.71e-0611373M47637
PathwayKEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

3.60e-0612373M47649
PathwayKEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

3.60e-0612373M47628
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

4.68e-0613373M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

PLCB1 PLCB3 PLCB4

1.32e-0518373M47659
PathwayKEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY

PLCB1 PLCB3 PLCB4

1.57e-0519373M47596
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

1.57e-0519373M47543
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

PLCB1 PLCB3 PLCB4

1.84e-0520373M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

PLCB1 PLCB3 PLCB4

2.14e-0521373M47689
PathwayKEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

2.14e-0521373M47638
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

2.14e-0521373M47542
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

PLCB1 PLCB3 PLCB4

2.48e-0522373M39795
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

PLCB1 PLCB3 PLCB4

2.48e-0522373M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

PLCB1 PLCB3 PLCB4

2.48e-0522373M47675
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

PLCB1 PLCB3 PLCB4

2.84e-0523373M47676
PathwayWP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION

SPHK1 PLCB1 PLCB3

3.68e-0525373M39384
PathwayKEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

4.15e-0526373M47557
PathwayWP_SPHINGOLIPID_METABOLISM_IN_SENESCENCE

CERS2 SPHK1 PLCB1

5.21e-0528373M42536
PathwayKEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

5.21e-0528373M47508
PathwayWP_GPR143_IN_MELANOCYTES_AND_RETINAL_PIGMENT_EPITHELIUM_CELLS

PLCB1 PLCB3 PLCB4

6.44e-0530373M42578
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

7.11e-0531373M47554
PathwayKEGG_GAP_JUNCTION

PLCB1 PLCB3 PLCB4 TUBA4A

8.73e-0590374M4013
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

PLCD3 PLCD4

9.99e-056372M47960
PathwayREACTOME_MRNA_EDITING_C_TO_U_CONVERSION

APOBEC3D APOBEC3B

1.40e-047372MM15412
PathwayWP_KISSPEPTINKISSPEPTIN_RECEPTOR_SYSTEM_IN_THE_OVARY

PLCB1 PLCB3 PLCB4

1.43e-0439373M39905
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

PLCB1 PLCB3 PLCB4

1.43e-0439373MM14496
PathwayREACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION

PLCB1 PLCB3

1.86e-048372MM15032
PathwayREACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION

PLCB1 PLCB3

1.86e-048372M27356
PathwayREACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION

PLCB1 PLCB3

1.86e-048372MM15100
PathwayREACTOME_MRNA_EDITING

APOBEC3D APOBEC3B

2.39e-049372MM15445
PathwayREACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION

PLCB1 PLCB3

2.98e-0410372M1825
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

3.00e-0450373M47951
PathwayREACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION

PLCB1 PLCB3

3.63e-0411372M27317
PathwayREACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION

PLCB1 PLCB3

3.63e-0411372MM15035
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

PLCB1 PLCB3 PLCB4

3.76e-0454373M26911
PathwayKEGG_LONG_TERM_POTENTIATION

PLCB1 PLCB3 PLCB4

8.07e-0470373M3115
PathwayKEGG_LONG_TERM_DEPRESSION

PLCB1 PLCB3 PLCB4

8.07e-0470373M8232
PathwayREACTOME_OPIOID_SIGNALLING

PLCB1 PLCB3 PLCB4

8.41e-0471373MM14491
PathwayWP_ALZHEIMERS_DISEASE

PLCB1 PLCB3 PLCB4

9.49e-0474373MM15962
PathwayWP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3

PLCB1 PLCB3 PLCB4

9.87e-0475373M39568
PathwayBIOCARTA_EDG1_PATHWAY

SPHK1 PLCB1

1.24e-0320372MM1456
PathwayREACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS

PLCB1 PLCB3

1.36e-0321372M27409
PathwayREACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS

PLCB1 PLCB3

1.36e-0321372MM15159
PathwayWP_SYNTHESIS_OF_CERAMIDES_AND_1DEOXYCERAMIDES

CERS2 SPHK1

1.50e-0322372M45544
PathwayBIOCARTA_EDG1_PATHWAY

SPHK1 PLCB1

1.50e-0322372M10579
PathwayWP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR

SPHK1 PLCB3

1.64e-0323372MM15952
PathwayREACTOME_OPIOID_SIGNALLING

PLCB1 PLCB3 PLCB4

1.67e-0390373M6467
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

CERS2 SPHK1

1.94e-0325372MM15931
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

CERS2 SPHK1

2.09e-0326372M39784
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

CERS2 SPHK1

2.09e-0326372MM15892
PathwayWP_HIPPO_SIGNALING_REGULATION

PLCB1 PLCB3 PLCB4

2.13e-0398373M39830
PathwayREACTOME_PROTEIN_FOLDING

FBXW9 SPHK1 TUBA4A

2.13e-0398373M776
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

CERS2 SPHK1

2.26e-0327372M39863
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

CERS2 SPHK1

2.26e-0327372MM14646
PathwayPID_CXCR4_PATHWAY

ITCH PLCB1 PLCB3

2.26e-03100373M124
PathwayKEGG_MELANOGENESIS

PLCB1 PLCB3 PLCB4

2.32e-03101373M7761
PathwayKEGG_GNRH_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

2.32e-03101373M1979
PathwayPID_IL8_CXCR1_PATHWAY

PLCB1 PLCB3

2.43e-0328372M252
PathwayWP_SPHINGOLIPID_PATHWAY

CERS2 SPHK1

2.78e-0330372M39501
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

PLCB1 PLCB3

2.78e-0330372M18193
PathwayPID_AR_NONGENOMIC_PATHWAY

PLCB1 PLCB3

2.97e-0331372M213
PathwayREACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

PLCB1 PLCB3

3.16e-0332372M14309
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

PLCB1 PLCB3

3.16e-0332372MM15143
PathwayWP_WNT_SIGNALING_WP428

PLCB1 PLCB3 PLCB4

3.20e-03113373M39669
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

PLCB1 PLCB3 PLCB4

3.36e-03115373M9387
PathwayREACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

PLCB1 PLCB3

3.36e-0333372MM15027
PathwayPID_IL8_CXCR2_PATHWAY

PLCB1 PLCB3

3.57e-0334372M210
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

CERS2 SPHK1

4.21e-0337372M554
PathwayREACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS

FBXW9 SPHK1

4.67e-0339372M3871
PathwayWP_ALZHEIMERS_DISEASE

PLCB1 PLCB3 PLCB4 TUBA4A

4.69e-03261374M42565
PathwayPID_ER_NONGENOMIC_PATHWAY

PLCB1 PLCB3

4.91e-0340372M41
PathwayPID_THROMBIN_PAR1_PATHWAY

PLCB1 PLCB3

5.66e-0343372M238
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

PLCB1 PLCB3 PLCB4

5.82e-03140373M42572
PathwayREACTOME_CA2_PATHWAY

PLCB1 PLCB3

6.18e-0345372MM15040
PathwayKEGG_WNT_SIGNALING_PATHWAY

PLCB1 PLCB3 PLCB4

7.17e-03151373M19428
Pubmed

Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway.

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4

2.57e-16185071979339
Pubmed

Expression of phospholipase C isozymes by murine B lymphocytes.

PLCD3 PLCB1 PLCD4 PLCB3 PLCB4

1.25e-12105052033248
Pubmed

Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line.

PLCB1 PLCD4 PLCB3 PLCB4

4.74e-1095047589147
Pubmed

Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.

PLCB1 PLCD4 PLCB3 PLCB4

4.74e-10950410501179
Pubmed

Genetic mapping of the human and mouse phospholipase C genes.

PLCD3 PLCB1 PLCD4 PLCB3 PLCB4

1.15e-09335058672127
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

FRK PLCZ1 GCNT7 ADAM19 PLCB1 PLCD4 PLCB3 PLCL1 CPM PLXND1 SEMA4C

5.74e-09730501134857952
Pubmed

Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cbeta in mouse brain.

PLCB1 PLCB3 PLCB4

1.12e-0845039753089
Pubmed

Phospholipase C-β1 potentiates glucose-stimulated insulin secretion.

PLCB1 PLCB3 PLCB4

1.12e-08450331268747
Pubmed

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.

PLCB1 PLCB3 PLCB4

1.12e-08450323006664
Pubmed

Phospholipase C isozymes selectively couple to specific neurotransmitter receptors.

PLCB1 PLCB3 PLCB4

1.12e-0845039305844
Pubmed

Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation.

PLCB1 PLCB3 PLCB4

1.12e-08450315174099
Pubmed

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease.

PLCB1 PLCD4 PLCB3 PLCB4

3.28e-08235049730685
Pubmed

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases.

PLCB1 PLCD4 PLCB3 PLCB4

3.28e-08235049278385
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

PLCB1 PLCD4 PLCB3 PLCB4

3.93e-082450410843712
Pubmed

Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.

PLCB1 PLCB3 PLCB4

5.57e-0865038739298
Pubmed

Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets.

PLCB1 PLCB3 PLCB4

5.57e-0865032841328
Pubmed

Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.

PLCZ1 PLCB1 PLCB3 PLCB4

6.47e-082750420336759
Pubmed

Genetic dissection of gustatory sensitivity to bitterness (sucrose octaacetate) in mice.

PLCB1 PLCB3 PLCB4

9.75e-08750310609087
Pubmed

Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.

PLCB1 PLCD4 PLCB3 PLCB4

2.69e-073850412482669
Pubmed

Implantation failure in mice with a disruption in Phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism.

PLCB1 PLCB3 PLCB4

3.33e-071050323295235
Pubmed

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.

PLCB1 PLCB3 PLCB4

1.26e-061550328578927
Pubmed

Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.

PLCD3 PLCB1 PLCD4 PLCB3 PLCB4

1.87e-0614150520056178
Pubmed

Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus.

DPY19L2 DPY19L2P2

2.03e-06250222764053
Pubmed

A locus for a human hereditary cataract is closely linked to the gamma-crystallin gene family.

CRYGC CRYGD

2.03e-0625023025877
Pubmed

Phospholipase C-β1 and β4 contribute to non-genetic cell-to-cell variability in histamine-induced calcium signals in HeLa cells.

PLCB1 PLCB4

2.03e-06250224475116
Pubmed

Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan.

PLCB1 PLCB4

2.03e-06250226434682
Pubmed

Expression of sperm PLCζ and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion.

PLCZ1 DPY19L2

2.03e-06250229339016
Pubmed

Complementary stripes of phospholipase Cbeta3 and Cbeta4 expression by Purkinje cell subsets in the mouse cerebellum.

PLCB3 PLCB4

2.03e-06250216566000
Pubmed

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.

DPY19L2 DPY19L2P2

2.03e-06250225354700
Pubmed

Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.

DPY19L2 DPY19L2P2

2.03e-06250225354701
Pubmed

Phospholipase Cbeta serves as a coincidence detector through its Ca2+ dependency for triggering retrograde endocannabinoid signal.

PLCB1 PLCB4

2.03e-06250215664177
Pubmed

Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons.

PLCB3 PLCB4

2.03e-06250217114052
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

PLCB1 PLCB3 PLCB4

3.65e-062150330270038
Pubmed

Murine Leukemia Virus P50 Protein Counteracts APOBEC3 by Blocking Its Packaging.

APOBEC3D APOBEC3B

6.07e-06350232641479
Pubmed

Physiological functions of phospholipase C delta-type.

PLCD3 PLCD4

6.07e-06350218177742
Pubmed

APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.

APOBEC3D APOBEC3B

6.07e-06350227602762
Pubmed

Differential distribution of phospholipase C beta isoforms and diaglycerol kinase-beta in rodents cerebella corroborates the division of unipolar brush cells into two major subtypes.

PLCB1 PLCB4

6.07e-06350223503970
Pubmed

Anti-Friend virus antibody is associated with recovery from viremia and loss of viral leukemia cell-surface antigens in leukemic mice. Identification of Rfv-3 as a gene locus influencing antibody production.

APOBEC3D APOBEC3B

6.07e-063502286744
Pubmed

A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.

APOBEC3D APOBEC3B

6.07e-06350222691411
Pubmed

Mutation analysis of CRYAA, CRYGC, and CRYGD associated with autosomal dominant congenital cataract in Brazilian families.

CRYGC CRYGD

6.07e-06350219390652
Pubmed

Studies on the restriction of murine leukemia viruses by mouse APOBEC3.

APOBEC3D APOBEC3B

6.07e-06350222666481
Pubmed

APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.

APOBEC3D APOBEC3B

6.07e-06350224577894
Pubmed

Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope.

DPY19L2 DPY19L2P2

6.07e-06350225775128
Pubmed

Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.

APOBEC3D APOBEC3B

6.07e-06350224725948
Pubmed

APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.

APOBEC3D APOBEC3B

6.07e-06350216648136
Pubmed

Duplication and relocation of the functional DPY19L2 gene within low copy repeats.

DPY19L2 DPY19L2P2

6.07e-06350216526957
Pubmed

Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.

APOBEC3D APOBEC3B

6.07e-06350223533681
Pubmed

The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.

APOBEC3D APOBEC3B

6.07e-06350220702647
Pubmed

Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv-2 gene in the Q/TL region of mouse MHC.

APOBEC3D APOBEC3B

6.07e-0635021541833
Pubmed

In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models.

APOBEC3D APOBEC3B

6.07e-06350227356895
Pubmed

IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.

APOBEC3D APOBEC3B

6.07e-06350223315078
Pubmed

Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.

APOBEC3D APOBEC3B

6.07e-06350220980520
Pubmed

Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.

APOBEC3D APOBEC3B

6.07e-06350225589647
Pubmed

Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex.

APOBEC3D APOBEC3B

6.07e-063502284359
Pubmed

Phospholipase C in mouse oocytes: characterization of beta and gamma isoforms and their possible involvement in sperm-induced Ca2+ spiking.

PLCB1 PLCB3

6.07e-0635028687404
Pubmed

Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove.

APOBEC3D APOBEC3B

6.07e-06350220617165
Pubmed

Membrane targeting of C2 domains of phospholipase C-delta isoforms.

PLCD3 PLCD4

6.07e-06350211706040
Pubmed

Impact of Suboptimal APOBEC3G Neutralization on the Emergence of HIV Drug Resistance in Humanized Mice.

APOBEC3D APOBEC3B

6.07e-06350231801862
Pubmed

Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strain.

APOBEC3D APOBEC3B

6.07e-06350239208378
Pubmed

Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure.

APOBEC3D APOBEC3B

6.07e-06350231943071
Pubmed

Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.

APOBEC3D APOBEC3B

6.07e-06350223671100
Pubmed

Structural perspectives on HIV-1 Vif and APOBEC3 restriction factor interactions.

APOBEC3D APOBEC3B

6.07e-06350231518043
Pubmed

Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.

APOBEC3D APOBEC3B

6.07e-06350220566830
Pubmed

Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.

APOBEC3D APOBEC3B

6.07e-0635027884913
Pubmed

N-linked glycosylation protects gammaretroviruses against deamination by APOBEC3 proteins.

APOBEC3D APOBEC3B

6.07e-06350225505062
Pubmed

Molecular analysis of γ1, γ3, and α class switch recombination junctions in APOBEC3-deficient mice using high-throughput sequencing.

APOBEC3D APOBEC3B

6.07e-06350231595054
Pubmed

The gamma-crystallins and human cataracts: a puzzle made clearer.

CRYGC CRYGD

6.07e-06350210521291
Pubmed

Cloning, expression, and chaperone-like activity of human alphaA-crystallin.

CRYGC CRYGD

6.07e-0635028943244
Pubmed

APOBEC3 signature mutations in chronic lymphocytic leukemia.

APOBEC3D APOBEC3B

6.07e-06350224840555
Pubmed

Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.

APOBEC3D APOBEC3B

6.07e-06350217967065
Pubmed

Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.

APOBEC3D APOBEC3B

6.07e-06350220335265
Pubmed

Deaminase-Dead Mouse APOBEC3 Is an In Vivo Retroviral Restriction Factor.

APOBEC3D APOBEC3B

6.07e-06350229593034
Pubmed

Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing.

APOBEC3D APOBEC3B

6.07e-06350231830125
Pubmed

Requirement for CD4(+) T cells in the Friend murine retrovirus neutralizing antibody response: evidence for functional T cells in genetic low-recovery mice.

APOBEC3D APOBEC3B

6.07e-0635029765497
Pubmed

Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.

APOBEC3D APOBEC3B

6.07e-06350221998583
Pubmed

Biochemical and biological studies of mouse APOBEC3.

APOBEC3D APOBEC3B

6.07e-06350224453360
Pubmed

Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway.

APOBEC3D APOBEC3B

6.07e-06350238115583
Pubmed

APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription.

APOBEC3D APOBEC3B

6.07e-06350223449789
Pubmed

Primary phospholipase C and brain disorders.

PLCB1 PLCB4

6.07e-06350226639088
Pubmed

Effects of zidovudine on Friend virus complex infection in Rfv-3r/s genotype-containing mice used as a model for HIV infection.

APOBEC3D APOBEC3B

6.07e-0635022157836
Pubmed

Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells.

APOBEC3D APOBEC3B

6.07e-06350235458563
Pubmed

Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.

APOBEC3D APOBEC3B

6.07e-06350222275865
Pubmed

APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice.

APOBEC3D APOBEC3B

6.07e-06350218434399
Pubmed

Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.

APOBEC3D APOBEC3B

6.07e-06350219153238
Pubmed

Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.

APOBEC3D APOBEC3B

6.07e-06350218772436
Pubmed

Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene.

APOBEC3D APOBEC3B

6.07e-063502293683
Pubmed

Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene.

APOBEC3D APOBEC3B

6.07e-06350219150103
Pubmed

Methylation and carbamylation of human gamma-crystallins.

CRYGC CRYGD

6.07e-06350212876325
Pubmed

Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.

APOBEC3D APOBEC3B

6.07e-06350218786991
Pubmed

Initial sequencing and comparative analysis of the mouse genome.

APOBEC3D APOBEC3B

6.07e-06350212466850
Pubmed

Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection.

APOBEC3D APOBEC3B

1.21e-05450224821801
Pubmed

Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G.

APOBEC3D APOBEC3B

1.21e-05450220363737
Pubmed

Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo.

APOBEC3D APOBEC3B

1.21e-05450218983852
Pubmed

Nuclear PLCs affect insulin secretion by targeting PPARγ in pancreatic β cells.

PLCB1 PLCD4

1.21e-05450221974932
Pubmed

Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils.

APOBEC3D APOBEC3B

1.21e-05450229343743
Pubmed

APOBEC3 regulates keratinocyte differentiation and expression of Notch3.

APOBEC3D APOBEC3B

1.21e-05450231400166
Pubmed

The mouse eye lens obsolescence (Elo) mutant: studies on crystallin gene expression and linkage analysis between the mutant locus and the gamma-crystallin genes.

CRYGC CRYGD

1.21e-0545023428594
Pubmed

APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.

APOBEC3D APOBEC3B

1.21e-05450215674295
Pubmed

Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication.

APOBEC3D APOBEC3B

1.21e-05450221873525
Pubmed

Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs.

PLCB1 PLCB3

1.21e-0545029188725
InteractionPLCL1 interactions

PLCZ1 PLCD4 PLCL1

1.94e-0611473int:PLCL1
InteractionPLCZ1 interactions

PLCD3 PLCZ1 PLCL1

1.12e-0519473int:PLCZ1
Cytoband20p12

PLCB1 PLCB4

1.05e-041450220p12
Cytoband2q33.3

CRYGC CRYGD

4.96e-04305022q33.3
Cytoband3q22.1

ASTE1 PLXND1

9.73e-04425023q22.1
CytobandEnsembl 112 genes in cytogenetic band chr2q33

CRYGC CRYGD PLCL1

1.47e-03205503chr2q33
Cytoband2q35

PLCD4 TUBA4A

3.39e-03795022q35
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCD3 PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 PLCL1

2.66e-1519357832
GeneFamilyPhospholipases

PLCD3 PLCZ1 PLCH2 PLCB1 PLCD4 PLCB3 PLCB4

1.38e-1242357467
GeneFamilyApolipoprotein B mRNA editing enzyme catalytic subunits

APOBEC3D APOBEC3B

2.37e-0412352406
GeneFamilyBeta-gamma crystallins

CRYGC CRYGD

3.76e-04153521359
GeneFamilyEF-hand domain containing

PLCZ1 PLCH2 PLCD4 PLS1

8.17e-04219354863
GeneFamilySH2 domain containing

FRK SOCS4

1.63e-02101352741
CoexpressionKRAS.AMP.LUNG_UP.V1_DN

GVINP1 PLCH2 EMILIN2 SNTG1 PLCB3

6.84e-06142495M2859
CoexpressionGSE29618_BCELL_VS_MDC_UP

ADAM19 GVINP1 PLEKHA2 RMC1 TUBA4A

3.09e-05194495M4943
CoexpressionGSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_DN

CERS2 HSPBAP1 ASTE1 SDF2 TECPR1

3.16e-05195495M9824
CoexpressionGSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP

ADAM19 BUB1 CPM DPY19L2P2 APOBEC3B

3.49e-05199495M9410
CoexpressionGSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP

CHAF1A PLCB1 PLCL1 DNAJC6 PLS1

3.49e-05199495M6839
CoexpressionGSE4142_GC_BCELL_VS_MEMORY_BCELL_UP

ADAM19 ITCH SPHK1 PLCD4 PLCL1

3.57e-05200495M6397
CoexpressionGSE17721_POLYIC_VS_CPG_6H_BMDC_UP

ITCH PAXBP1 SPHK1 PLEKHA2 SDF2

3.57e-05200495M3943
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A NAGLU ASTE1 PLCL1 PLXND1

1.59e-0617650524b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHAF1A NAGLU ASTE1 PLCL1 PLXND1

1.63e-06177505f360f7099570d248531897b96e0de282e58f59e9
ToppCellNS-critical-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPHK1 EMILIN2 FLVCR2 CPM PLXND1

2.63e-06195505ee8743d39996bb756f50db32748e8a902d3294b8
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP2 ADAM19 SPHK1 PLCB1 PLCB4

2.83e-061985059ab0db78394e730f6866b2db80047149024ad5f6
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP2 ADAM19 SPHK1 PLCB1 PLCB4

2.83e-06198505e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

DLGAP2 PLCH2 ALDH7A1 EPHA7

2.69e-0515450438d346402417960044ae999e61f0092b46f2b591
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 TREML4 EMILIN2 PLCB1

2.83e-051565042ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCellfacs-SCAT-Fat-24m|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYGC CRYGD TREML4 ATP4B

3.28e-05162504b824f30c723c9c7d8e8c8a8dc3f88d4eed29dd67
ToppCellIIF-Other-HSPC|IIF / Disease, Lineage and Cell Type

DLGAP2 CRYGD DPY19L2 PLCB4

3.36e-051635041e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCellHealthy_donor-HSPC|World / disease group, cell group and cell class (v2)

DLGAP2 CRYGD DPY19L2 PLCB4

3.69e-0516750470630ebdfee8171d625811844f8a7c94736d101e
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS PLCD4 DNAJC6 TUBA4A

3.78e-051685040f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DLGAP2 CRYGD DPY19L2 PLCB4

3.96e-051705045bb577e2c4bd275fbe4ee23ff8c007b2fcb90e56
ToppCellHealthy_donor-HSPC|Healthy_donor / disease group, cell group and cell class (v2)

DLGAP2 CRYGD DPY19L2 PLCB4

4.14e-05172504bc7549faadfc92c683c0e26bea380458706774b5
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DLGAP2 CRYGD DPY19L2 PLCB4

4.33e-0517450466df78280f657978c4a568010ae7d7943869af90
ToppCellcontrol-Others-CD34+_GATA2+_cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CRYGD DPY19L2 PLCB4 DNAJC6

4.73e-051785042120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCellControl-Hematopoietic_SC-HSPC|Control / Disease group, lineage and cell class

CRYGD DPY19L2 FBXW9 PLCB4

5.16e-0518250414e347c0e6444410f1948851407bb18c706569f4
ToppCellControl-Hematopoietic_SC|Control / Disease group, lineage and cell class

CRYGD DPY19L2 FBXW9 PLCB4

5.16e-0518250443243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHK1 CHAF1A BUB1 EMILIN2

5.61e-05186504ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CRYGD FBXW9 DNAJC6 ALDH7A1

5.61e-05186504ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHK1 CHAF1A BUB1 EMILIN2

5.61e-051865047cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CRYGD FBXW9 DNAJC6 ALDH7A1

5.85e-05188504c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DLGAP2 EYS ADAM19 PLCB4

5.85e-051885042db80767903703e7e0a1a37c598f7877a909ee94
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DLGAP2 ADAM19 SPHK1 PLCB4

5.85e-05188504aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRK PLCB1 PLCB4 CPM

5.97e-051895048c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRK PLCB1 PLCB4 CPM

5.97e-051895045d902a4660a27548764bf04c6de152b565da835c
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BUB1 PLCB4 CPM PLS1

5.97e-05189504c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SNTG1 PLCB1 FLVCR2 KDM6A

6.35e-05192504916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellNS-moderate-d_0-4-Myeloid-Resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADAM19 SPHK1 EMILIN2 PLXND1

6.48e-05193504e530d4349b257f2590c799bf082ed6318700c526
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

SNTG1 PLCB1 FLVCR2 KDM6A

6.48e-05193504e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM19 CHAF1A BUB1 APOBEC3B

6.61e-051945045771a28a61f4d9b5479891f3224909ab003cb241
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EMILIN2 FLVCR2 CPM PLXND1

7.01e-051975045fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERS2 PLCL1 CPM PLS1

7.15e-05198504a183afe4c2034323f77abfa080f359d67da35e8f
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EMILIN2 PLEKHA2 PLCL1 CPM

7.15e-05198504cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCellPBMC-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

SPHK1 PLCB1 FLVCR2 PLXND1

7.15e-05198504fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCellSepsis-URO-Lymphocyte-T/NK-MAIT|URO / Disease, condition lineage and cell class

EYS TREML4 DPY19L2 PLS1

7.15e-0519850475db638278d4be2b0f406cd8871058a8352c5a86
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EMILIN2 PLEKHA2 PLCL1 CPM

7.15e-05198504d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TREML4 SPHK1 EMILIN2 FLVCR2

7.15e-051985049a77038e5db0ea757fd7ebcab294785b166ddc12
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EMILIN2 FLVCR2 CPM PLXND1

7.15e-05198504641e7be258303bb9782d19fcf8693f317581d3b8
ToppCellcritical-Myeloid-Non-resident_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EMILIN2 FLVCR2 CPM PLXND1

7.29e-05199504193325768b17d3123ae855317f381a01088b5dac
ToppCellPBMC-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

SPHK1 EMILIN2 PLCB1 PLXND1

7.29e-05199504ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLCD3 GCNT7 ASTE1

2.56e-04110503c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-mesenchymal_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PLCD3 EPHA7 SEMA4C

3.39e-04121503176de42c088988fe1a7838f96add26ee8a30e543
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DLGAP2 EYS SNTG1

4.00e-0412850391072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADAM19 EMILIN2 PLS1

4.18e-041305030a6b87635e650df431a88f2e6396abead84d901d
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADAM19 EMILIN2 PLS1

4.37e-0413250312d2765908d5ef36f96ca3b54643a8859f807b93
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADAM19 EMILIN2 PLS1

4.37e-04132503e0733a41d2281d25786b9fd1da629f2e58f15b67
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CRYGD DPY19L2 DNAJC6

4.88e-041375036d90da42dcc06aa895f920218055068f3c76d57d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 SNTG1 PLCD4

5.52e-04143503990844ca674d30b2924c74b45bed4fdfb8463fa7
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CERS2 SOCS4 NAGLU

5.75e-0414550347a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DLGAP2 EYS SNTG1

6.10e-04148503d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DLGAP2 EYS SNTG1

6.35e-041505030205318a870e091add66ee4305747dda9f51510d
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 EMILIN2 PLXND1

6.47e-041515033105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

PLCH2 ALDH7A1 EPHA7

6.60e-0415250372499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|343B / Donor, Lineage, Cell class and subclass (all cells)

APOBEC3D PLCH2 TUBA4A

6.72e-041535030b3b199678d4a70b0590393568c69454bece5c14
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 EMILIN2 PLXND1

6.85e-041545031e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCellPND07-28-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TREML4 GVINP1 EMILIN2

7.11e-04156503166f7b1220eaf8e1149dde260dd85a094855c54f
ToppCellPND07-28-samps-Myeloid-Granulocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TREML4 GVINP1 EMILIN2

7.11e-041565035e1c5a7c9293b886920739cf766521df7f69726c
ToppCellfacs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 EMILIN2 PLXND1

7.24e-041575039d4308312301cb922f156a7b6aededc9e1c62807
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 PLCD4 PLCB4

7.38e-041585037960337d87afecf2692ab65e5991f052ceddfacc
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DLGAP2 EYS SNTG1

7.51e-041595035335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAGLU EMILIN2 PLS1

7.65e-041605035d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLVCR2 PLXND1 TECPR1

7.65e-0416050333050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellBasal_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

PLCL1 ALDH7A1 EPHA7

7.65e-04160503b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 EMILIN2 PLXND1

7.65e-041605031f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT7 ADAM19 EMILIN2

7.79e-04161503e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT7 ADAM19 EMILIN2

7.79e-041615038280a029026c272cae9649b27575831b0dd4e242
ToppCell367C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EMILIN2 FLVCR2 APOBEC3B

7.79e-04161503c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell367C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EMILIN2 FLVCR2 APOBEC3B

7.79e-041615039864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FRK CRYGD PLCB4

7.93e-04162503e73c644ce1db34f1d390878954e86fa0b3a455a1
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue-7|TCGA-Stomach / Sample_Type by Project: Shred V9

PLCD4 PLCL1 EPHA7

7.93e-04162503b115b5799137122bd60696f8ae2aebadad6cd044
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FBXW9 PLCL1 CPM

7.93e-0416250364353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCellHealthy_Control-Lymphoid-B-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ADAM19 PLCH2 TUBA4A

8.07e-04163503d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A BUB1 ATP4B

8.07e-041635033f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellHealthy_Control-Lymphoid-B|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ADAM19 PLCH2 TUBA4A

8.07e-041635030f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCellURO-Lymphocyte-T_NK-MAIT|URO / Disease, Lineage and Cell Type

TREML4 DPY19L2 PLS1

8.22e-04164503cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPY19L2 EMILIN2 PLCB4

8.22e-04164503d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITCH TREML4 EMILIN2

8.36e-04165503e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITCH TREML4 EMILIN2

8.36e-041655030fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 EMILIN2 PLCB1

8.51e-04166503e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 EMILIN2 PLCB1

8.51e-041665033ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 EMILIN2 PLCB1

8.51e-04166503f751cbd01d4978ded7755874ab60504f6291afd7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 BUB1 TECPR1

8.66e-041675030130743084dbcb20e10f96715d30961122150cbf
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBXW9 CHAF1A DNAJC6

8.66e-0416750329d271643f3a1718b53db77b7d093ec94225a824
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 BUB1 TECPR1

8.66e-041675037bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 BUB1 TECPR1

8.66e-04167503c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

APOBEC3D ASTE1 TUBA4A

8.81e-041685032781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CHAF1A SOCS4 PLS1

8.81e-0416850394cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITCH TREML4 EMILIN2

8.81e-0416850300cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

CRYGD PLCB4 DNAJC6

8.81e-0416850390b33962adb77d8326dee403712118398b4d1315
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 EMILIN2 PLCB1

8.81e-04168503f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A BUB1 ATP4B

8.96e-04169503121768fc51fc3441ec725346a1bbe29e21d05971
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITCH TREML4 EMILIN2

8.96e-0416950390c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CPM PLXND1 APOBEC3B

9.12e-041705039ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 ADAM19 SPHK1

9.12e-041705036035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 ADAM19 SPHK1

9.12e-04170503c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

CHAF1A BUB1 APOBEC3B

9.12e-041705035319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 EMILIN2 PLCB1

9.12e-041705037cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 ADAM19 SPHK1

9.12e-04170503dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellhealthy_donor-Myeloid-Monocytic-Developing_Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

DPY19L2 BUB1 TUBA4A

9.12e-04170503cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 PLCB1 PLXND1

9.12e-04170503a78d9789c3e7c84a36e1bd380192d7aba4a4d443
Drugnorfloxacin

CRYGC PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.53e-1045496CID000004539
Drugxanthate

PLCZ1 CRYGD PLCB1 PLCD4 PLCB3 PLCB4

1.07e-0950496CID000008823
Drug2-chloroadenosine

FRK PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

2.16e-09102497CID000008974
Drugchlorphentermine

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.38e-0926495CID000010007
DrugAC1L1G9E

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.54e-0928495CID000003586
DrugAC1Q6T8I

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.12e-0930495CID000000343
Drugcetyltrimethylammonium bromide

DLGAP2 PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

7.16e-0968496CID000002681
DrugST271

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.16e-0835495CID006439072
Drugnorathyriol

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.55e-0837495CID005281656
DrugTriton X-100 solution

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4 CPM

2.91e-08148497CID000560774
DrugD-myo-inositol 1,4-bisphosphate

PLCD3 PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.99e-0886496CID000000805
Drugcompound 48/80

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

3.34e-08151497CID000104735
DrugLypressin

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.36e-0847495CID000005772
Drugsevoflurane

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4

9.91e-08105496CID000005206
DrugL-quisqualic acid

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 CPM TUBA4A

1.11e-07180497CID000001209
Drugalpha-methylhomocysteine-thiolactone

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.20e-0755495CID000133014
DrugAC1Q6SH8

PLCD3 PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.80e-07116496CID000000009
DrugAC1L9K72

PLCZ1 SPHK1 EMILIN2 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

1.80e-07290498CID000446872
DrugSKF83742

PLCB1 PLCB3 PLCB4

1.86e-076493CID000130828
DrugC10A

PLCB1 PLCB3 PLCB4

1.86e-076493CID000041624
Drug(?-Fluprostenol

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.03e-0761495CID000003391
Drug8-iso Misoprostol

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.21e-0762495CID004183806
DrugD 609

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.59e-0764495CID000002940
DrugLopac-P-178

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.27e-0767495CID005478935
Drugsulprostone

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

4.38e-0771495CID005312153
Drugmilrinone

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

8.19e-07150496CID000004197
Drugoxotremorine-M

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

8.48e-0781495CID000004629
Drugenantio-PAF-C16

PLCZ1 CHAF1A PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

8.72e-07244497CID000002499
Drug3-nitrocoumarin

PLCB1 PLCB3 PLCB4

1.11e-0610493CID002799766
Druglysosphingomyelin

PLCZ1 SPHK1 PLCB1 PLCD4 PLCB3 PLCB4

1.19e-06160496CID000005263
Drugreactive blue 2

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.21e-0687495CID000656725
Drugisopetasin

PLCB1 PLCB3 PLCB4

1.53e-0611493CID005318627
DrugNSC350593

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

1.67e-06269497CID000004364
DrugAraf-TC

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.78e-0694495CID000100788
Drugglycerol-3-phosphocholine

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

1.82e-06172496CID000000823
DrugADP beta S

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.98e-0696495CID005310996
DrugAC1L1II7

PLCB1 PLCB3 PLCB4

2.03e-0612493CID000004589
Drugpapaverine

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

2.08e-06176496CID000004680
DrugAC1MQNLW

PLCB1 PLCB3 PLCB4

3.35e-0614493CID003504628
DrugPl-cs

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.37e-06107495CID006450086
Drugspiperone

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.53e-06108495CID000005265
Drugsodium fluoride

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.53e-06108495CID000005235
Drugphosphatidate

PLCZ1 SPHK1 SNTG1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

3.59e-06432498CID005460104
Drugisopropyl-beta-D-thioglucoside

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.87e-06110495CID000552632
Druggentamicin

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4

4.11e-06198496CID000003467
DrugRHC 80267

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

4.22e-06112495CID000005063
DrugT1 p

CRYGC CRYGD CHAF1A KDM6A

4.39e-0651494CID000657023
Drugacephylline

PLS1 ALDH7A1

4.54e-062492CID000069550
Drugm-3M3FBS

PLCB1 PLCB3 PLCB4

5.14e-0616493CID000761523
DrugET-18-OCH3

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.92e-06120495CID000001392
DrugClorocruoro Hem

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

6.68e-06123495CID003518809
Drugheptachlor

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

8.43e-06129495CID000003589
Drugsapintoxin A

PLCB1 PLCB3 PLCB4

8.86e-0619493CID000108085
Drugketanserin

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

9.09e-06131495CID000003822
Drugdecanoate

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

9.09e-06131495CID000002969
DrugAC1L9ZFX

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.01e-05134495CID000504578
Drugpyridoxal

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.05e-05135495CID000001050
DrugAC1Q5THZ

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4 SDF2 ALDH7A1

1.08e-05502498CID000001959
Drugimipramine

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 TUBA4A

1.09e-05235496CID000003696
Drugkinin 9

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 CPM TUBA4A

1.19e-05363497CID000006026
Drugglyceraldehyde

PLCB1 PLCB3 PLCB4 TUBA4A ALDH7A1

1.26e-05140495CID000000751
DrugAC1L1O6Q

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.30e-05141495CID000058035
Drugmuscarine

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.44e-05144495CID000009308
Drug6-trans-leukotriene B4

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

1.45e-05247496CID000000169
Drugfenoldopam

PLCB1 PLCB3 PLCB4 ALDH7A1

1.56e-0570494CID000003340
DrugDethiocoenzyme A

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.59e-05147495CID000003002
Drug8-isoprostaglandin E1

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

1.59e-05251496CID000000214
DrugSulcrate

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.64e-05148495CID006398525
DrugAC1NFC6P

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.64e-05148495CID000004587
Druglead compounds

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.75e-05150495CID000073212
Druglindane

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

1.99e-05154495CID000000727
Drugmonomethyl phthalate

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.05e-05155495CID000020392
Drugtifomycin

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 PLS1

2.07e-05263496CID000000298
Drughistamine

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4 TUBA4A ALDH7A1

2.36e-05560498CID000000774
Drugamiodarone

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.39e-05160495CID000002156
Drugmiltefosine

PLCB1 PLCD4 PLCB3 PLCB4

2.40e-0578494CID000003599
Drug2-(aminomethyl)pyrrolidine

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.46e-05161495CID000072032
Drugtriphosphoinositide

PLCD3 PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.55e-05273496CID009543520
Drugnalidixic acid

CRYGC PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

2.77e-05277496CID000004421
Drugfluoride

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

2.83e-05278496CID000014917
DrugAC1Q5S71

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.20e-05170495CID000000501
DrugU46619

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

3.25e-05285496CID000005618
Drug1,2-diglyceride

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.67e-05175495CID000192866
DrugCortisporin

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

3.88e-05177495CID000004454
Drugpentoxifylline

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

4.65e-05304496CID000004740
Drugprostaglandin F2

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

4.83e-05306496CID000000160
Drug12(S)-hydroxyeicosatetraenoic acid

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.30e-05189495CID000001413
Drugnsc25485

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4

5.38e-05312496CID000004605
Drugallodeoxycholic acid

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.44e-05190495CID000002987
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

PLCB3 PLCL1 CPM DNAJC6 PLS1

5.71e-051924952450_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

PLCB3 PLCL1 CPM DNAJC6 PLS1

5.71e-051924953114_UP
Drugprazosin

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

5.85e-05193495CID000004893
Drug4-hydroxynonenal

PLCZ1 NAGLU PLCB1 PLCD4 PLCB3 PLCB4 ALDH7A1

6.28e-05471497CID000001693
Drugdiisopropylfluorophosphate

CRYGC PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

6.29e-05321496CID000005936
DrugSulmazole [73384-60-8]; Down 200; 14uM; PC3; HT_HG-U133A

BUB1 CPM KDM6A ALDH7A1 SEMA4C

6.45e-051974954009_DN
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; HL60; HT_HG-U133A

ASTE1 PLCB4 PLXND1 KDM6A SEMA4C

6.61e-051984952348_DN
DrugAG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A

PLCH2 BUB1 PLCB1 KDM6A ALDH7A1

6.61e-051984955944_DN
DrugAC1OAGGW

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

7.44e-05203495CID006857364
DrugGF109203X

CRYGC PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

8.78e-05341496CID000002396
DrugNDGA

PLCZ1 PLCB1 PLCD4 PLCB3 PLCB4

9.96e-05216495CID000004534
Diseasecataract 2 multiple types (implicated_via_orthology)

CRYGC CRYGD

2.38e-062462DOID:0110235 (implicated_via_orthology)
DiseaseCATARACT, AUTOSOMAL DOMINANT

CRYGC CRYGD

1.42e-054462C1858679
Diseaseretinal degeneration (implicated_via_orthology)

CRYGC EYS PLCB4

1.87e-0533463DOID:8466 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

SPHK1 PLCB1 PLCB3 PLXND1 ATP4B

2.11e-05215465DOID:9970 (implicated_via_orthology)
DiseaseCATARACT, COPPOCK-LIKE

CRYGC CRYGD

8.50e-059462C1852438
DiseaseCataract, Pulverulent

CRYGC CRYGD

8.50e-059462C1833118
DiseaseCataract microcornea syndrome

CRYGC CRYGD

8.50e-059462C1861829
Diseasehomostachydrine measurement

EYS PLCB4

1.83e-0413462EFO_0021164
DiseaseNuclear cataract

CRYGC CRYGD

3.58e-0418462C0392557
DiseaseNuclear non-senile cataract

CRYGC CRYGD

3.58e-0418462C1112705
Diseaseinferior parietal cortex volume measurement

CRYGC FRK

4.00e-0419462EFO_0010307
DiseasePseudoaphakia

CRYGC CRYGD

6.42e-0424462C0524524
DiseaseLens Opacities

CRYGC CRYGD

6.42e-0424462C1510497
DiseaseHematopoetic Myelodysplasia

SPHK1 PLCB1

9.40e-0429462C2713368
DiseaseAstigmatism

DLGAP2 PLCL1 CPM

1.08e-03129463HP_0000483
DiseaseCataract

CRYGC CRYGD

1.53e-0337462C0086543
DiseaseCongenital small ears

PLCB4 KDM6A

1.88e-0341462C0152423
Diseaserectum cancer

DLGAP2 PLCL1

1.97e-0342462EFO_1000657
Diseasemyocardial infarction (biomarker_via_orthology)

PLCB1 PLCB3 KDM6A

2.00e-03160463DOID:5844 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NFVCNEGQPFMPWYK

APOBEC3D

171

Q96AK3
FQCVEMLSNKPWNYQ

BUB1

971

O43683
CWENFVYNEGQQFMP

APOBEC3B

156

Q9UH17
YGWNNAIAMICGNVC

ALDH7A1

201

P49419
GMCLTYQEQCQQLWG

ADAM19

516

Q9H013
INNMWKQQCGYNPNY

GVINP1

1986

Q7Z2Y8
QQFYWLCQQNMDPSA

DLGAP2

921

Q9P1A6
MCWYVHPQVLQSFQQ

CHAF1A

816

Q13111
EFQRYCWNPDTGQML

ATP4B

16

P51164
MFNYAGWKNTCNNIF

CERS2

251

Q96G23
GFCPLNSFQWRNMNT

ASTE1

171

Q2TB18
SFQGQPFIWCMLHNF

NAGLU

396

P54802
CMSYQEPQLWAGDNQ

FBXW9

351

Q5XUX1
VPMSYNNGTFCCNKW

EYS

3051

Q5T1H1
WCSIGVLYQQQNQPM

KDM6A

321

O15550
FRNWMNSLGVNPYIN

PLS1

401

Q14651
CVHGNLTFWYMQNPV

PLXND1

1056

Q9Y4D7
QNVINCFPKQWFMNL

PAXBP1

826

Q9Y5B6
CLSNVAFMLPWQFAQ

DPY19L2

331

Q6NUT2
YQVCQVMEPNQNNWL

EPHA7

71

Q15375
SSNYMPQLFWNVGCQ

PLCB3

656

Q01970
KVQYFRFWCQQLAMP

ITCH

531

Q96J02
SNCPQQFYNIMLECW

FRK

456

P42685
QQPAIFCNMVFDWPA

HSPBAP1

41

Q96EW2
GCWMLYEQPNYSGLQ

CRYGD

41

P07320
LQGGMQDYNYIWAQC

CPM

261

P14384
FQWNYVINLCGQDFP

GCNT7

196

Q6ZNI0
RNMYNWLLQNPKNVC

DNAJC6

146

O75061
MCNSFQWIQYGSINN

FLVCR2

96

Q9UPI3
GCWMLYERPNYQGQQ

CRYGC

41

P07315
SFIQAQYNCAWNQMP

EMILIN2

66

Q9BXX0
QYNCAWNQMPCPSAL

EMILIN2

71

Q9BXX0
CLSNVAFMLPWQFAQ

DPY19L2P2

141

Q6ZN68
ANCLLWYMDNPQNLA

PLEKHA2

36

Q9HB19
SSNYMPQIFWNAGCQ

PLCB4

631

Q15147
PQIFWNAGCQMVSLN

PLCB4

636

Q15147
NYNPQELWNAGCQMV

PLCD4

561

Q9BRC7
RNFPVNQQIVYMGWC

SNTG1

276

Q9NSN8
SNFNPQEFWNIGCQM

PLCZ1

416

Q86YW0
QEFWNIGCQMVALNF

PLCZ1

421

Q86YW0
INNNPCYWGVMDKYA

SOCS4

281

Q8WXH5
SAPNWQLYFNQLQAM

SEMA4C

286

Q9C0C4
QPSQNNYWKAMEGIF

SDF2

181

Q99470
PQDFWNCGCQIVAMN

PLCL1

656

Q15111
MIQLTQNDSGFYWCG

TREML4

96

Q6UXN2
NLNVNWYMYCPESAV

RMC1

151

Q96DM3
NYSPQEMWNSGCQLV

PLCD3

596

Q8N3E9
SNYNPQPFWNAGCQM

PLCH2

691

O75038
QPFWNAGCQMVALNY

PLCH2

696

O75038
AYENQRWNPMGGFCE

TECPR1

71

Q7Z6L1
FNNLQWYRQNTGMGP

TRAV7

51

A0A075B6U4
SSNYMPQLFWNAGCQ

PLCB1

606

Q9NQ66
PQLFWNAGCQMVALN

PLCB1

611

Q9NQ66
QGQVHPNYFWMVSGC

SPHK1

351

Q9NYA1
QAGVQMGNACWELYC

TUBA4A

11

P68366