Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TRIO POLR3H TUT7 LRRK2 OAS2 DAPK1 PFKP MAP3K4 PRKAG3 JAK3 PHKG1 PARP4 LIMK1 FES DCLK3 PAK3 PIP5K1B PRKDC CDK1 FAM20A MAP4K4 EIF2AK3	8.25e-05	938	189	22	GO:0016772
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TRIO LRRK2 DAPK1 MAP3K4 PRKAG3 PHKG1 LIMK1 DCLK3 PAK3 PRKDC CDK1 FAM20A MAP4K4 EIF2AK3	9.35e-05	446	189	14	GO:0004674
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TRIO LRRK2 DAPK1 PFKP MAP3K4 PRKAG3 JAK3 PHKG1 LIMK1 FES DCLK3 PAK3 PIP5K1B PRKDC CDK1 FAM20A MAP4K4 EIF2AK3	1.44e-04	709	189	18	GO:0016773
GeneOntologyMolecularFunction	protein serine kinase activity	TRIO LRRK2 DAPK1 MAP3K4 PHKG1 LIMK1 DCLK3 PAK3 PRKDC CDK1 MAP4K4 EIF2AK3	1.85e-04	363	189	12	GO:0106310
GeneOntologyMolecularFunction	protein kinase activity	TRIO LRRK2 DAPK1 MAP3K4 PRKAG3 JAK3 PHKG1 LIMK1 FES DCLK3 PAK3 PRKDC CDK1 FAM20A MAP4K4 EIF2AK3	1.97e-04	600	189	16	GO:0004672
GeneOntologyMolecularFunction	kinase activity	TRIO LRRK2 DAPK1 PFKP MAP3K4 PRKAG3 JAK3 PHKG1 LIMK1 FES DCLK3 PAK3 PIP5K1B PRKDC CDK1 FAM20A MAP4K4 EIF2AK3	3.57e-04	764	189	18	GO:0016301
Domain	Patatin	PNPLA2 PNPLA6 PNPLA7	7.81e-05	9	186	3	PF01734
Domain	PNPLA	PNPLA2 PNPLA6 PNPLA7	7.81e-05	9	186	3	PS51635
Domain	Patatin/PLipase_A2-rel	PNPLA2 PNPLA6 PNPLA7	7.81e-05	9	186	3	IPR002641
Domain	Cyt_P450_E_grp-I_CYP2D-like	CYP2D6 CYP2U1	9.86e-05	2	186	2	IPR008069
Domain	UPF0028	PNPLA6 PNPLA7	9.86e-05	2	186	2	PS01237
Domain	Single_hybrid_motif	PDHX CTDP1 PC	2.00e-04	12	186	3	IPR011053
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	SART3 FLNB RPL32 KIF1A HSPA4L GPX8 HUWE1 PFKP ANKHD1 NPLOC4 CRKL PDIA4 ACSL1 TRMT10C PTPRK P4HB DDX54 ANKRD17 BOLA2 PRKDC CDK1 SIPA1L2 GCN1 ATP2B1 XPR1	1.80e-10	974	191	25	28675297
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SART3 FLNB RPL32 KIF1A TRIO HSPA4L SYNE1 URB2 API5 HUWE1 ANKHD1 CRKL HNRNPU PDIA4 TRMT10C P4HB DDX54 DOCK7 CTNNBL1 CENPV BOLA2 PRKDC CDK1 PC DDX21 MAP4K4 GCN1 ATP2B1 TOP2B	1.24e-09	1425	191	29	30948266
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNB TRIO TUT7 PARP4 ARHGEF40 DOCK7 MTTP ANKRD17 PRKDC HERC2 GCN1 TOP2B	1.48e-09	202	191	12	33005030
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PNPLA2 MORN1 TRIO WNT7B FBRSL1 PER1 HUWE1 ITGA5 ANKHD1 TBC1D24 JAK3 ARHGEF40 PNPLA6 CTDP1 DIP2C LRP5 CENPV MICAL3 PRKDC HERC2 SIPA1L2 ZNF839 PC GCN1	1.11e-08	1105	191	24	35748872
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SART3 FLNB DIS3L2 GPX8 TUT7 URB2 HUWE1 PFKP ANKHD1 HNRNPU ACSL1 PCGF6 ARHGEF40 PNPLA6 P4HB MICAL2 DDX54 CTNNBL1 ANKRD17 PRKDC CDK1 HERC2 DDX21 GCN1 ATP2B1 TOP2B	3.08e-08	1353	191	26	29467282
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SART3 RPL32 MAGOH HSPA4L SYNE1 PFKP PIGU PDHX PDIA4 USP31 PCGF6 TRMT10C PNPLA6 P4HB CLPTM1 DDX54 CENPV BOLA2 HERC2 C9orf72 SIPA1L2 DDX21 MAP4K4 ATP2B1 EIF2AK3 TOP2B XPR1	5.18e-08	1487	191	27	33957083
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SART3 FLNB SYN3 TRIO PER1 TACC2 HUWE1 PDHX CRKL HNRNPU TBC1D24 TRMT10C P4HB DOCK7 PAK3 BOLA2 SIPA1L2 PC MAP4K4 GCN1 ALDH5A1 ELP4 AKAP7	8.60e-08	1139	191	23	36417873
Pubmed	Defining the membrane proteome of NK cells.	RPL32 OAS2 ANO10 API5 HUWE1 PFKP PIGU HNRNPU ACSL1 PARP4 PNPLA6 CLPTM1 DDX54 CTNNBL1 ANKRD17 PRKDC CDK1 HERC2 DDX21 ALG6 GCN1 ATP2B1 EIF2AK3	1.34e-07	1168	191	23	19946888
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SART3 FLNB KIF1A TUT7 URB2 HUWE1 PFKP ANKHD1 PDIA4 P4HB DDX54 DOCK7 ANKRD17 PRKDC HERC2 DDX21 GCN1	1.43e-07	653	191	17	22586326
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB SLC9A8 KIF1A MORN1 TRIO WNT7B FBRSL1 HUWE1 NPLOC4 HNRNPU NIT2 THAP4 PNPLA6 MICAL2 AUTS2 DIP2C PAK3 ANKRD17 LRP5 KATNIP MICAL3 PNPLA7 TMEM143 ZNF839 MLPH ATP2B1	2.00e-07	1489	191	26	28611215
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	KIF1A HSPA4L GPX8 HS6ST2 TUT7 URB2 HUWE1 PFKP PDIA4 ARHGEF40 PPP2R5E CTPS2 PNPLA6 PTPRK CLPTM1 ANKRD17 PRKDC TMEM143 GCN1 IPO11	2.90e-07	942	191	20	31073040
Pubmed	Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.	NCF1 PRKDC NCF1B	1.62e-06	5	191	3	21715554
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	FLNB MAGOH MOGAT1 HSPA4L MYH7B VPS4B HUWE1 PDHX HNRNPU PDIA4 TRMT10C P4HB CLPTM1 PRKDC CDK1 GCN1 ATP2B1 IPO11	1.92e-06	878	191	18	37223481
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ACSL6 SYNE1 FSTL5 URB2 MAP3K4 USP31 PPP2R5E DOCK7 KATNIP MICAL3 SIPA1L2 DOP1B	2.96e-06	407	191	12	12693553
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	SART3 FLNB POLR3H VPS4B HUWE1 PFKP NPLOC4 CRKL TRMT10C CTPS2 TRMT2A TIPIN DOCK7 ANKRD17 CDK1 HERC2 MAP4K4 GCN1 AKAP7	3.20e-06	1005	191	19	19615732
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ITGA11 SUSD6 HSPA4L GPX8 HS6ST2 TUT7 CNTNAP3 TMTC2 ITGA5 PIGU PDIA4 PTPRK P4HB MICAL2 CLPTM1 DPY19L4 LRP5 BOLA2 ALG6 ATP2B1 EIF2AK3	3.21e-06	1201	191	21	35696571
Pubmed	Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle.	MB NCF1 NCF1B	3.22e-06	6	191	3	30504831
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	RPL32 GPX8 SLFN5 URB2 ANO10 ITGA5 HNRNPU TBC1D24 PDIA4 ZNF800 PPP2R5E PTPRK P4HB MICAL2 CLPTM1 DOCK7 AUTS2 PRKDC CDK1 ATP2B1 TOP2B	3.29e-06	1203	191	21	29180619
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SART3 FLNB RPL32 HSPA4L TACC2 HUWE1 PFKP ANKHD1 NPLOC4 CRKL HNRNPU TRMT10C CTPS2 P4HB DDX54 CTNNBL1 BOLA2 PRKDC CDK1 PC DDX21 GCN1 TOP2B	3.57e-06	1415	191	23	28515276
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNB SYNE1 URB2 HUWE1 PFKP CRKL HNRNPU PDIA4 P4HB DDX54 DOCK7 PRKDC CDK1 HERC2 DDX21 MAP4K4 GCN1 ATP2B1 TOP2B	4.19e-06	1024	191	19	24711643
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SART3 ACSL6 FLNB RPL32 SYN3 TRIO HSPA4L SYNE1 DAPK1 PFKP PDHX HNRNPU TBC1D24 USP31 PPP2R5E PNPLA6 P4HB MICAL2 DOCK7 MICAL3 SIPA1L2 PC ATP2B1	4.29e-06	1431	191	23	37142655
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	HUWE1 PFKP HNRNPU PRKDC DDX21 GCN1	5.05e-06	79	191	6	26446488
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SART3 ERCC1 HSPA4L TUT7 HUWE1 MAP3K4 DDX54 ANKRD17 CDK1 HERC2 EIF2AK3 TOP2B	6.53e-06	440	191	12	34244565
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	PFKP PPP2R5E P4HB PRKDC CDK1 GCN1 IPO11 DOP1B	8.41e-06	183	191	8	23956138
Pubmed	Human Elongator facilitates RNA polymerase II transcription through chromatin.	KAT2B CTDP1 ELP4	8.95e-06	8	191	3	11818576
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	SART3 URB2 HUWE1 PFKP ANKHD1 MAP3K4 HNRNPU CTPS2 CTNNBL1 ANKRD17 PRKDC CDK1 PC GCN1 TOP2B	9.07e-06	704	191	15	29955894
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	FLNB HSPA4L NPLOC4 CRKL HNRNPU PDIA4 DOCK7 ANKRD17 MICAL3 PRKDC CDK1 MAP4K4 GCN1 ATP2B1 EIF2AK3	9.70e-06	708	191	15	39231216
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	SYNE1 HUWE1 HNRNPU PDIA4 TRMT10C P4HB CENPV PRKDC CDK1 DDX21 GCN1 ATP2B1	1.09e-05	463	191	12	34901782
Pubmed	Comparative mapping of the region of human chromosome 7 deleted in williams syndrome.	NCF1 LIMK1 NCF1B	1.34e-05	9	191	3	10330122
Pubmed	Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions.	PNPLA2 PNPLA6 PNPLA7	1.34e-05	9	191	3	19029121
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SART3 TUT7 FBRSL1 ANKHD1 NPLOC4 HNRNPU PARP4 ARHGEF40 TRMT2A DOCK7 ANKRD17 MICAL3 PZP MAP4K4	1.61e-05	650	191	14	38777146
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	PDHX HNRNPU ARHGEF40 DOCK7 PRKDC DDX21 GCN1 ATP2B1	1.72e-05	202	191	8	24639526
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	SART3 RPL32 PFKP ANKHD1 CRKL HNRNPU ZNF800 DDX54 ANKRD17 BOLA2 PRKDC PC DDX21 GCN1	1.76e-05	655	191	14	35819319
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	HUWE1 PIGU NPLOC4 HNRNPU PCGF6 P4HB CLPTM1 PRKDC CDK1 HERC2 DDX21 GCN1 IPO11 SLC16A10	1.82e-05	657	191	14	36180527
Pubmed	Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.	FLNB RPL32 HSPA4L TUT7 PFKP ANKHD1 HNRNPU PPP2R5E CTPS2 ANKRD17 DDX21	1.90e-05	411	191	11	36652389
Pubmed	Real-time resolution of point mutations that cause phenovariance in mice.	JAK3 PRKDC MAP4K4	1.90e-05	10	191	3	25605905
Pubmed	Characterization of the human patatin-like phospholipase family.	PNPLA2 PNPLA6 PNPLA7	1.90e-05	10	191	3	16799181
Pubmed	A role of DNA-PK for the metabolic gene regulation in response to insulin.	KAT2B PRKDC TOP2B	1.90e-05	10	191	3	19303849
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SART3 FLNB HSPA4L GPX8 API5 PFKP HNRNPU PDIA4 TRMT10C ANKRD17 LRP5 PRKDC CDK1 DDX21 MAP4K4 ATP2B1	2.00e-05	847	191	16	35235311
Pubmed	UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.	PRKDC CDK1 PC GCN1	2.16e-05	30	191	4	32867711
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNB VPS4B RUSC1 HUWE1 ANKHD1 CRKL DOCK7 ANKRD17 BOLA2 PC GCN1	2.21e-05	418	191	11	34709266
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	FLNB HNRNPU P4HB PRKDC DDX21 GCN1	2.46e-05	104	191	6	36055981
Pubmed	Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.	HUWE1 PFKP PRKDC DDX21 GCN1	2.78e-05	64	191	5	22865885
Pubmed	Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity.	PNPLA6 PNPLA7	3.00e-05	2	191	2	12640454
Pubmed	Loss of both phospholipid and triglyceride transfer activities of microsomal triglyceride transfer protein in abetalipoproteinemia.	P4HB MTTP	3.00e-05	2	191	2	23475612
Pubmed	ERp72, an abundant luminal endoplasmic reticulum protein, contains three copies of the active site sequences of protein disulfide isomerase.	PDIA4 P4HB	3.00e-05	2	191	2	2295602
Pubmed	Susceptibility of wild mouse cells to exogenous infection with xenotropic leukemia viruses: control by a single dominant locus on chromosome 1.	MLPH XPR1	3.00e-05	2	191	2	2991590
Pubmed	Modest association of malignant melanoma with the rs910873 and rs1885120 markers on chromosome 20: a population-based study.	MYH7B PIGU	3.00e-05	2	191	2	20224305
Pubmed	HIV protease inhibitor Lopinavir induces apoptosis of primary effusion lymphoma cells via suppression of NF-κB pathway.	JAK3 PRKDC	3.00e-05	2	191	2	24012878
Pubmed	Nonstructural 5A protein of hepatitis C virus interacts with pyruvate carboxylase and modulates viral propagation.	P4HB PC	3.00e-05	2	191	2	23861867
Pubmed	Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors.	ACSL6 ACSL1	3.00e-05	2	191	2	10548543
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	3.00e-05	2	191	2	26807827
Pubmed	Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and secretion of apolipoprotein B lipoproteins.	P4HB MTTP	3.00e-05	2	191	2	16478722
Pubmed	Stromal Integrin α11β1 Affects RM11 Prostate and 4T1 Breast Xenograft Tumors Differently.	ITGA11 PRKDC	3.00e-05	2	191	2	26990302
Pubmed	Impact of Janus Kinase 3 on Cellular Ca Release, Store Operated Ca(2+) Entry and Na(+)/Ca(2+) Exchanger Activity in Dendritic Cells.	JAK3 SLC8A1	3.00e-05	2	191	2	26279433
Pubmed	Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein.	P4HB MTTP	3.00e-05	2	191	2	8111381
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	3.00e-05	2	191	2	31150793
Pubmed	DIS3L2 Promotes Progression of Hepatocellular Carcinoma via hnRNP U-Mediated Alternative Splicing.	DIS3L2 HNRNPU	3.00e-05	2	191	2	31331910
Pubmed	Death-associated protein kinase 1 variation and Parkinson's disease.	LRRK2 DAPK1	3.00e-05	2	191	2	21749573
Pubmed	Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase.	PNPLA6 PNPLA7	3.00e-05	2	191	2	18086666
Pubmed	hnRNP-U is a specific DNA-dependent protein kinase substrate phosphorylated in response to DNA double-strand breaks.	HNRNPU PRKDC	3.00e-05	2	191	2	19351595
Pubmed	DNA-dependent protein kinase interacts functionally with the RNA polymerase II complex recruited at the human immunodeficiency virus (HIV) long terminal repeat and plays an important role in HIV gene expression.	CTDP1 PRKDC	3.00e-05	2	191	2	21450944
Pubmed	B56beta, a regulatory subunit of protein phosphatase 2A, interacts with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching.	PPP2R5B PPP2R5E	3.00e-05	2	191	2	18385213
Pubmed	C9orf72 hexanucleotide repeat expansion and Guam amyotrophic lateral sclerosis-Parkinsonism-dementia complex.	LRRK2 C9orf72	3.00e-05	2	191	2	23588498
Pubmed	Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains.	ACSL6 ACSL1	3.00e-05	2	191	2	16834775
Pubmed	[Rare forms of autosomal recessive spinocerebellar ataxia associated with mutations in the ANO10 (ATX-ANO10) and SYNE1 (ATX-SYNE1) genes].	SYNE1 ANO10	3.00e-05	2	191	2	39269294
Pubmed	Modification Effect of PARP4 and ERCC1 Gene Polymorphisms on the Relationship between Particulate Matter Exposure and Fasting Glucose Level.	ERCC1 PARP4	3.00e-05	2	191	2	35627777
Pubmed	Plasma membrane Ca2+-ATPase and NCX1 Na+/Ca2+ exchanger expression in distal convoluted tubule cells.	SLC8A1 ATP2B1	3.00e-05	2	191	2	12060584
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	HSPA4L URB2 ANKHD1 CRKL PDIA4 TRMT2A P4HB GCN1 IPO11	3.08e-05	285	191	9	32838362
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	PFKP ANKHD1 TRMT10C PNPLA6 DOCK7 CENPV PRKDC CDK1 PC DDX21 MAP4K4 GCN1 TOP2B	3.12e-05	601	191	13	33658012
Pubmed	Human homology and candidate genes for the Dominant megacolon locus, a mouse model of Hirschsprung disease.	CYP2D6 WNT7B MB	3.46e-05	12	191	3	9027489
Pubmed	Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.	PPP2R5B PPP2R5E PRKDC	3.46e-05	12	191	3	16541024
Pubmed	Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.	NPLOC4 HNRNPU P4HB PRKDC	4.04e-05	35	191	4	22337587
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	FLNB HUWE1 PFKP ANKHD1 PDIA4 DOCK7 ANKRD17 PRKDC DDX21 GCN1 ATP2B1 ALDH5A1	4.38e-05	534	191	12	35032548
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SART3 FLNB MAGOH SYNE1 TUT7 FBRSL1 API5 ANKHD1 HNRNPU TRMT10C P4HB DDX54 PRKDC DDX21 GCN1	4.39e-05	807	191	15	22681889
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	SART3 ITGA11 ERCC1 GPX8 TRPC4 TUT7 LRRK2 RUSC1 DAPK1 TACC2 ANO10 ARSI ARSL GRIFIN MICAL3 HERC2 SIPA1L2 PC EIF2AK3	4.45e-05	1215	191	19	15146197
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	RPL32 SLC9A8 PDHX CRKL HNRNPU TRMT10C P4HB DOCK7 CENPV BOLA2 PRKDC CDK1 DDX21 GCN1 ALDH5A1	4.51e-05	809	191	15	32129710
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	FLNB HUWE1 DOCK7 PRKDC GCN1	4.92e-05	72	191	5	36376293
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	SART3 RPL32 HSPA4L API5 HUWE1 ANKHD1 NPLOC4 CRKL HNRNPU TRMT10C PPP2R5E CTPS2 P4HB TIPIN CTNNBL1 PRKDC CDK1 PC DDX21 ELP4	5.05e-05	1335	191	20	29229926
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	HUWE1 PDHX HNRNPU TRMT10C PPP2R5E PNPLA6 DDX54 DOCK7 ANKRD17 PRKDC HERC2 SIPA1L2 DDX21	5.82e-05	639	191	13	23443559
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	PFKP HNRNPU PDIA4 P4HB PRKDC PC DDX21 GCN1 ATP2B1	6.21e-05	312	191	9	37120454
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	GALC HSPA4L AOX1 PDHX PRKAG3 JAK3 PXDNL EIF2AK3 TOP2B	6.36e-05	313	191	9	20800603
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SART3 FLNB RPL32 HSPA4L API5 HUWE1 PFKP ANKHD1 HNRNPU PDIA4 LRRIQ1 P4HB DOCK7 ANKRD17 MICAL3 PRKDC CDK1 GCN1	6.97e-05	1149	191	18	35446349
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	RUSC1 HUWE1 PARP4 PNPLA6 P4HB HERC2 GCN1	7.02e-05	182	191	7	31067453
Pubmed	Establishment and analysis of a mouse model that regulates sex-related differences in liver drug metabolism.	CYP2D6 CYP3A43 CYP2U1	7.07e-05	15	191	3	29968852
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TRIO HUWE1 ITGA5 PDIA4 USP31 TRMT10C PPP2R5B PPP2R5E PTPRK P4HB DDX54 MICAL3 CDK1 HERC2 PC GCN1 ATP2B1	7.41e-05	1049	191	17	27880917
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	SART3 FLNB RPL32 HNRNPU PDIA4 P4HB PRKDC CDK1 DDX21 GCN1	7.54e-05	397	191	10	21319273
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	MAGOH ANO10 ITGA5 PDIA4 TRMT10C P4HB CLPTM1 DDX54 CENPV BOLA2 CDK1 MAP4K4 ALG6 ATP2B1 EIF2AK3 SLC16A10	7.98e-05	952	191	16	38569033
Pubmed	Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.	KIF1A VPS4B HUWE1 PFKP TRMT10C TRMT2A PC ATP2B1 IPO11	8.09e-05	323	191	9	24797263
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	RPL32 HSPA4L HUWE1 ZNF800 DDX54 PRKDC CDK1 TOP2B	8.47e-05	253	191	8	29911972
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	CNTNAP3B PNPLA2 GPX8 CNTNAP3 HUWE1 PFKP PIGU PDHX NPLOC4 BROX ARSL DPY19L4 PRKDC PC ALG6 ALDH5A1 IPO11	8.50e-05	1061	191	17	33845483
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RPL32 TUT7 TACC2 URB2 PDHX HNRNPU DDX54 CENPV PRKDC CDK1 HERC2 DDX21 GCN1 TOP2B	8.58e-05	759	191	14	35915203
Pubmed	Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.	NCF1 NCF1B	8.97e-05	3	191	2	27044504
Pubmed	NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.	NCF1 NCF1B	8.97e-05	3	191	2	18787174
Pubmed	Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.	NCF1 NCF1B	8.97e-05	3	191	2	24873968
Pubmed	p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.	NCF1 NCF1B	8.97e-05	3	191	2	22184329
Pubmed	Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.	NCF1 NCF1B	8.97e-05	3	191	2	33545139
Pubmed	Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.	NCF1 NCF1B	8.97e-05	3	191	2	20142487
Pubmed	p47(phox) contributes to albuminuria and kidney fibrosis in mice.	NCF1 NCF1B	8.97e-05	3	191	2	25565313
Pubmed	Fes mediates the IL-4 activation of insulin receptor substrate-2 and cellular proliferation.	JAK3 FES	8.97e-05	3	191	2	11160325
Interaction	LRRC31 interactions	FLNB TRIO TUT7 PARP4 ARHGEF40 DOCK7 MTTP ANKRD17 PRKDC HERC2 GCN1 TOP2B	4.99e-07	205	187	12	int:LRRC31
Interaction	FLT1 interactions	MAGOH PFKP CRKL PDIA4 TRMT10C MICAL2 DDX54 PRKDC CDK1 GCN1 DOP1B	9.37e-07	179	187	11	int:FLT1
Interaction	DNAJB9 interactions	CNTNAP3B HS6ST2 CNTNAP3 TLR7 PDIA4 PTPRK P4HB CLPTM1 LRP5 RXFP1	1.99e-05	202	187	10	int:DNAJB9
Interaction	SIRT7 interactions	SART3 FLNB KIF1A TUT7 URB2 HUWE1 PFKP ANKHD1 PDIA4 KAT2B P4HB DDX54 DOCK7 CTNNBL1 ANKRD17 PRKDC CDK1 HERC2 DDX21 GCN1	2.06e-05	744	187	20	int:SIRT7
Interaction	PHKG2 interactions	DAPK1 HUWE1 PHKG1 CENPV PRKDC HERC2 GCN1	2.22e-05	91	187	7	int:PHKG2
Interaction	MTTP interactions	PDIA4 P4HB MTTP PRKDC	2.50e-05	19	187	4	int:MTTP
Interaction	ITGB3 interactions	FLNB HSPA4L HUWE1 ITGA5 P4HB PRKDC CDK1 GCN1 IPO11	3.07e-05	170	187	9	int:ITGB3
Interaction	FGF3 interactions	TUT7 URB2 ANKHD1 DDX54 ANKRD17 DDX21	3.37e-05	66	187	6	int:FGF3
Interaction	LGR4 interactions	DCT PDHX HNRNPU ARHGEF40 LRRIQ1 DOCK7 CYP2U1 PRKDC DDX21 GCN1 ATP2B1	3.52e-05	262	187	11	int:LGR4
GeneFamily	Patatin like phospholipase domain containing	PNPLA2 PNPLA6 PNPLA7	2.76e-05	10	113	3	466
Coexpression	HEVNER_CORTICAL_PLATE_POSTMITOTIC_NEURONS	ACSL6 RUSC1 PFKP TBC1D24 PPP2R5B AUTS2 MICAL3 XPR1	7.02e-06	136	190	8	MM407
Coexpression	GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN	TUT7 PER1 OAS2 TMTC2 HUWE1 PFKP HNRNPU USP31 HECTD2	1.64e-05	200	190	9	M6095
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	GPR155 ACSL6 TRIM2 SYN3 KIF1A HS6ST2 LRRK2 RUSC1 PFKP TBC1D24 FSIP2 SLC8A1 PTPRK CLVS2 DCLK3 AUTS2 PAK3 MICAL3 SPAG17 ATP2B1 DOP1B XPR1	1.86e-05	1106	190	22	M39071
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	SYNE1 LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B FAM20A MLPH	8.47e-08	180	190	9	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B FAM20A MLPH	1.53e-07	193	190	9	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B FAM20A MLPH	1.53e-07	193	190	9	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SYNE1 LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B CATSPERB MLPH	1.60e-07	194	190	9	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK2 DAPK1 TMTC2 TACC2 PTPRK MICAL2 PIP5K1B FAM20A MLPH	1.99e-07	199	190	9	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ITGA11 FSTL5 ADGRL4 PTPRK C1R RXFP1 SPAG17	9.66e-07	177	190	8	b6476a91abd06b8271b4d0ad7431d24b44022b47
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B FLNB GPR17 SYN3 CNTNAP3 ADGRL4 RXFP1 GPRC5B	1.35e-06	185	190	8	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB HSPA4L SLFN5 ITGA5 ADGRL4 USP31 RXFP1 GPRC5B	1.78e-06	192	190	8	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	LRRK2 TMTC2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B MLPH	1.78e-06	192	190	8	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B FAM20A MLPH	1.85e-06	193	190	8	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 LRRK2 TMTC2 TACC2 PTPRK MICAL2 PIP5K1B MLPH	1.92e-06	194	190	8	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 LRRK2 TMTC2 TACC2 PTPRK MICAL2 PIP5K1B MLPH	2.00e-06	195	190	8	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	THEMIS2 ACSL1 SLC8A1 PNPLA6 C9orf72 SIPA1L2 ATP2B1 SLC16A10	2.00e-06	195	190	8	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B FAM20A MLPH	2.24e-06	198	190	8	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B FAM20A MLPH	2.24e-06	198	190	8	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DAPK1 TMTC2 TACC2 PTPRK MICAL2 PIP5K1B FAM20A MLPH	2.32e-06	199	190	8	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DAPK1 TMTC2 TACC2 PTPRK MICAL2 PIP5K1B FAM20A MLPH	2.32e-06	199	190	8	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNB TRIM2 TMTC2 TACC2 PTPRK LRP5 MLPH DOP1B	2.41e-06	200	190	8	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DAPK1 TACC2 ANO10 ACSL1 LRP5 PIP5K1B MLPH DOP1B	2.41e-06	200	190	8	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB NCF1 PER1 ITGA5 ACSL1 P4HB NCF1B SLC16A10	2.41e-06	200	190	8	851c57187db8bc91a393655bca5f13e787a723d4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MOGAT1 LRRK2 OAS2 DAPK1 TMTC2 SLC8A1 C9orf72	5.12e-06	157	190	7	a98d06cef80bfe8481b0940abce2b29675e45812
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	LRRK2 DAPK1 TACC2 AUTS2 PIP5K1B FAM20A MLPH	6.55e-06	163	190	7	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	facs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HS6ST2 SDR42E1 MEI1 ADGB FES DCLK3 MLPH	7.10e-06	165	190	7	23955e3373660f827518e723ac62fba99753f375
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	TRIM2 HS6ST2 LRRK2 DAPK1 TACC2 PTPRK FAM20A	1.30e-05	181	190	7	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B MLPH	1.44e-05	184	190	7	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GPR155 ACSL6 SYNE1 SLFN5 HNRNPU JAK3 PPP2R5E	1.60e-05	187	190	7	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	NS-moderate-d_0-4-Myeloid-Non-resident_Macrophage\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	THEMIS2 TLR7 ITGA5 MEI1 ACSL1 SLC8A1 SLC16A10	1.60e-05	187	190	7	fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	LRRK2 TMTC2 TACC2 PTPRK MICAL2 PIP5K1B MLPH	1.66e-05	188	190	7	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B MLPH	1.71e-05	189	190	7	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 SYNE1 LRRK2 DAPK1 PFKP LRRIQ1 SPAG17	1.77e-05	190	190	7	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B MLPH	1.83e-05	191	190	7	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	MYH7B ECT2L TACC2 SLC8A1 PXDNL PIP5K1B XPR1	1.83e-05	191	190	7	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	LRRK2 TACC2 PTPRK AUTS2 PIP5K1B FAM20A MLPH	1.90e-05	192	190	7	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	LRRK2 TACC2 PTPRK MICAL2 AUTS2 PIP5K1B MLPH	1.90e-05	192	190	7	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	TRIM2 SYNE1 ECT2L TACC2 LRRIQ1 PTPRK SPAG17	2.10e-05	195	190	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	TRIM2 SYNE1 ECT2L TACC2 LRRIQ1 PTPRK SPAG17	2.10e-05	195	190	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	SYNE1 POLR3H LRRK2 TACC2 ARSL PIP5K1B MLPH	2.10e-05	195	190	7	0792c1e959e933b10ae987d821ff43020dfdabad
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	TRIM2 HS6ST2 SLFN5 TBC1D24 MICAL2 C1R FAM20A	2.24e-05	197	190	7	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LRRK2 ITGA5 HNRNPU JAK3 SLC8A1 ATP2B1 SLC16A10	2.24e-05	197	190	7	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D231\|Adult / Lineage, Cell type, age group and donor	THEMIS2 ACSL1 SLC8A1 PNPLA6 C9orf72 ATP2B1 SLC16A10	2.31e-05	198	190	7	79a415e19cedde13a88f5043d71557363f102322
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THEMIS2 NCF1 LRRK2 ACSL1 SLC8A1 ARHGEF40 C9orf72	2.31e-05	198	190	7	06201b34d3e38f22c93b759511f7b376504bac06
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	THEMIS2 NCF1 LRRK2 ACSL1 SLC8A1 ARHGEF40 C9orf72	2.31e-05	198	190	7	1ca91559fef231896e16180f5e050155c38f7cfa
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	TRIM2 KIF1A FSTL5 SLC8A1 ATP2B1 AKAP7 XPR1	2.39e-05	199	190	7	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DAPK1 TACC2 PTPRK MICAL2 PIP5K1B FAM20A MLPH	2.39e-05	199	190	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	TRIM2 KIF1A FSTL5 SLC8A1 ATP2B1 AKAP7 XPR1	2.39e-05	199	190	7	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THEMIS2 FLNB DAPK1 ITGA5 FAM20A ATP2B1 SLC16A10	2.39e-05	199	190	7	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Mesoderm\|10w / Sample Type, Dataset, Time_group, and Cell type.	ECT2L MEI1 MAP3K4 TIPIN MTTP C1R NIPA2	2.47e-05	200	190	7	9ef226ebb0a7cdb9431e2fa65faa2a7d67da590d
ToppCell	mild-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	THEMIS2 LRRK2 PER1 ACSL1 SLC8A1 ARHGEF40 C9orf72	2.47e-05	200	190	7	934c2efc780318c66d667ca75be0de350361d351
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SYNE1 TACC2 SLC8A1 HECTD2 DCLK3 PAK3 PZP	2.47e-05	200	190	7	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT MLPH	3.00e-05	84	190	5	1f8b19b159f83655f66cb99f8d10d9a87c08f78f
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT MLPH	3.00e-05	84	190	5	503490e9408d9638bcd089ef8ec0521924df9a5d
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT MLPH	3.00e-05	84	190	5	c37e1170d39ad015f724e373a547ea5b6ba45a84
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT MLPH	3.00e-05	84	190	5	7e4a76b65b0d34d9950f8b02590ff5a4b4534a27
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2-Tnr\|Thalamus / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT TULP2	3.56e-05	87	190	5	0c3a3ed1f279ed29a0113cc73ae590157a4b7334
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2\|Thalamus / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT TULP2	3.56e-05	87	190	5	a93dbe73b337cc2d93208822728b9badf30b6870
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)\|Thalamus / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT TULP2	3.56e-05	87	190	5	45ef27ba84f731e4b2188813cd6931950e5164ac
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	GPR17 ADAM18 MATN1 DCT TULP2	3.56e-05	87	190	5	5d1dbbd86d82cbce4f2a3365242eb92d9c821a9e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HS6ST2 MICAL2 BTN1A1 CATSPERB FAM20A XPR1	4.20e-05	148	190	6	9fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	GAMT LRRK2 DAPK1 TACC2 AUTS2 PIP5K1B	5.83e-05	157	190	6	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MOGAT1 DAPK1 ITGA5 ACSL1 SLC8A1 SIPA1L2	6.04e-05	158	190	6	1635a85fc73c544028418087f36d28957dd4f458
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MOGAT1 DAPK1 ITGA5 ACSL1 SLC8A1 SIPA1L2	6.04e-05	158	190	6	80841dadfa53bcde36a3e486408a095f78e772eb
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	POLR3H FSTL5 DAPK1 ETNPPL PC ALDH5A1	6.71e-05	161	190	6	347edb0de10850b7d16c40945751033289289c9b
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORN1 ARSI TMEM106A BTN1A1 MICAL3 PZP	6.71e-05	161	190	6	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ITGA11 SYN3 MEI1 PTPRK DCLK3 RXFP1	6.94e-05	162	190	6	2d28306c6125b31f11ea6d911a167b93a74907c5
ToppCell	368C-Epithelial_cells-Epithelial-A_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SYN3 TEDC2 WNT7B LRRK2 CNTNAP3 MLPH	7.43e-05	164	190	6	85f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR17 TRIO ADAM18 MATN1 TBC1D24 PAK3	7.43e-05	164	190	6	0853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 SYNE1 TRPC4 MICAL2 DCLK3 PIP5K1B	7.43e-05	164	190	6	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	368C-Epithelial_cells-Epithelial-A_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	SYN3 TEDC2 WNT7B LRRK2 CNTNAP3 MLPH	7.43e-05	164	190	6	144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	THEMIS2 OAS2 TLR7 CPN1 TMEM106A	7.62e-05	102	190	5	57ad3d48adeb41f6ab65883e61d3b1e74a94ad1a
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	THEMIS2 OAS2 TLR7 CPN1 TMEM106A	7.62e-05	102	190	5	9392288e284b71f3a208d9f283e6e3c944b7dd10
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	THEMIS2 OAS2 TLR7 CPN1 TMEM106A	7.62e-05	102	190	5	0ec549ee94da5f2d7275490e90d816c645f6d4fc
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	THEMIS2 OAS2 TLR7 CPN1 TMEM106A	7.62e-05	102	190	5	30fa92383898f370dabc41dd23d6907f14ba1a06
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	THEMIS2 OAS2 TLR7 CPN1 TMEM106A	7.62e-05	102	190	5	c58e09aaa11b664c7d99e91f903561fa18460f05
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MOGAT1 LRRK2 OAS2 DAPK1 TMTC2 SLC8A1	7.94e-05	166	190	6	28a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MOGAT1 LRRK2 OAS2 DAPK1 TMTC2 SLC8A1	7.94e-05	166	190	6	2a04915d534a83e65aa168435d6856125b5bdd78
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPN1 TMPRSS11F ADGB KAT2B PLEKHM3 CDK1	7.94e-05	166	190	6	63dc58864268b4e7779e4c45155022556fc634f9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRIM2 HS6ST2 LRRK2 DAPK1 PTPRK AKAP7	7.94e-05	166	190	6	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GPR17 HS6ST2 TRPC4 RLBP1 SLITRK2 CLVS2	8.21e-05	167	190	6	49b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AOX1 ETNPPL ACSL1 MTTP PZP PC	8.48e-05	168	190	6	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AOX1 ETNPPL ACSL1 MTTP PZP PC	8.48e-05	168	190	6	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	Control\|World / group, cell type (main and fine annotations)	SYNE1 TACC2 PTPRK MICAL2 PIP5K1B MLPH	8.48e-05	168	190	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GPR17 KIF1A HS6ST2 RLBP1 SLITRK2 CLVS2	8.77e-05	169	190	6	d9c3b22f62b882b8a2ea6fd9cf7afbe6d1775745
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-club_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FSTL5 WNT7B CPN1 MYO15A PC MLPH	9.06e-05	170	190	6	6de3778e8257c3330db0780c59238ca501fe5059
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-club_cell-club_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FSTL5 WNT7B CPN1 MYO15A PC MLPH	9.06e-05	170	190	6	60887da674ef1a735bad618235608312d8de63d3
ToppCell	droplet-Marrow-BM-1m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE1 NCF1 LRRK2 ETNPPL ANO10 ACSL1	9.35e-05	171	190	6	8a0c08f0aa3a80cd6346c81deb242e430ebd897b
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Deuterosomal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HSPA4L MB ADGB LRRIQ1 CDK1 SPAG17	9.35e-05	171	190	6	52aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPR17 DCT RLBP1 ADGB SLITRK2 DCLK3	9.66e-05	172	190	6	8d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 SYNE1 TRPC4 MICAL2 DCLK3 PIP5K1B	9.66e-05	172	190	6	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 SYNE1 TRPC4 MICAL2 DCLK3 PIP5K1B	9.66e-05	172	190	6	553701349444eb366df3c11f54bb093434f153c6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ITGA11 ADGRL4 PTPRK C1R RXFP1	9.97e-05	173	190	6	4ec147479b359cce1975d57a50ee1437a0e1e663
ToppCell	wk_20-22-Epithelial-PNS\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GPR17 SYN3 FSTL5 SLITRK2 ARSL SIPA1L2	9.97e-05	173	190	6	17b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCell	wk_20-22-Hematologic-Myeloid-Promyelocyte-like\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	THEMIS2 LRRK2 TBC1D24 ACSL1 PCGF6 TRMT10C	1.10e-04	176	190	6	ee33d7077a92c1fd371081e7c990c7266e711957
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SUSD6 SYNE1 TUT7 SLFN5 ADGRL4 ZNF800	1.17e-04	178	190	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	THEMIS2 CNTNAP3B CNTNAP3 ADGRL4 USP31 MICAL2	1.20e-04	179	190	6	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	THEMIS2 CNTNAP3B CNTNAP3 ADGRL4 USP31 MICAL2	1.20e-04	179	190	6	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	15-Distal-Epithelial-Neuroendocrine\|Distal / Age, Tissue, Lineage and Cell class	KIF1A FSTL5 CNTNAP3 ACSL1 PAK3 MLPH	1.20e-04	179	190	6	bc04789f0fbd293fdcea66acba8cf227af251b7a
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GPR17 HS6ST2 TRPC4 RLBP1 SLITRK2 CLVS2	1.28e-04	181	190	6	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB AOX1 PPP2R5B PC FAM20A GPRC5B	1.28e-04	181	190	6	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THEMIS2 CNTNAP3B ITGA11 FSTL5 CNTNAP3 RXFP1	1.32e-04	182	190	6	72e65a23cd36085bc880087d3cae92395de918a1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THEMIS2 CNTNAP3B ITGA11 FSTL5 CNTNAP3 RXFP1	1.32e-04	182	190	6	05c167158815bf25d509df59ab386e1990712765
Disease	blindness (implicated_via_orthology)	PNPLA6 PNPLA7 MYO15A	1.26e-05	8	182	3	DOID:1432 (implicated_via_orthology)
Disease	neurodegenerative disease (implicated_via_orthology)	TRPC4 LRRK2 NPLOC4 TBC1D24 PRKAG3 PNPLA6 PNPLA7	3.41e-05	145	182	7	DOID:1289 (implicated_via_orthology)
Disease	age-related macular degeneration, COVID-19	SYN3 TACC2 CPN1 NPLOC4 RLBP1	6.90e-05	69	182	5	EFO_0001365, MONDO_0100096
Disease	cathepsin L1 measurement	LRRK2 ADGB C9orf72	1.22e-04	16	182	3	EFO_0010619
Disease	chronic granulomatous disease (implicated_via_orthology)	NCF1 NCF1B	3.74e-04	5	182	2	DOID:3265 (implicated_via_orthology)
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	VPS4B PER1 ADGRL4	6.75e-04	28	182	3	DOID:1094 (implicated_via_orthology)
Disease	cortical surface area measurement	ACSL6 FLNB ITGA11 SLC9A8 TRIM2 PSG1 TUT7 DAPK1 NPLOC4 CRKL PCGF6 PPP2R5E LRRIQ1 FES AUTS2 PLEKHM3 SPAG17 PC MAP4K4	6.85e-04	1345	182	19	EFO_0010736
Disease	synophrys measurement	LRRIQ1 AUTS2 LRP5 HERC2	8.38e-04	68	182	4	EFO_0007906
Disease	non-alcoholic fatty liver disease	PNPLA2 CPN1 DOCK7 MTTP PIP5K1B MICAL3	9.61e-04	182	182	6	EFO_0003095
Disease	Leigh syndrome	PDHX PC	1.03e-03	8	182	2	cv:C0023264
Disease	cerebellar ataxia (implicated_via_orthology)	PNPLA6 PNPLA7	1.03e-03	8	182	2	DOID:0050753 (implicated_via_orthology)
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	1.03e-03	8	182	2	DOID:0060308 (implicated_via_orthology)
Disease	Schizophrenia and related disorders	CYP2D6 SYN3	1.32e-03	9	182	2	C0809983
Disease	mean reticulocyte volume	SYN3 PSG1 SUSD6 FBRSL1 URB2 CPN1 NPLOC4 TBC1D24 KAT2B ALG6 AKAP7 IPO11 SLC16A10	1.44e-03	799	182	13	EFO_0010701
Disease	hair colour measurement	MYH7B DCT NPLOC4 FES CTNNBL1 LRP5 CATSPERB HERC2 SIPA1L2 PC AKAP7	1.60e-03	615	182	11	EFO_0007822
Disease	adseverin measurement	CPN1 C1R	1.65e-03	10	182	2	EFO_0801358
Disease	hereditary spastic paraplegia (implicated_via_orthology)	PNPLA6 NIPA2 PNPLA7	2.38e-03	43	182	3	DOID:2476 (implicated_via_orthology)
Disease	Lenticulostriate Disorders	CYP2D6 XPR1	2.40e-03	12	182	2	C0750951
Disease	rheumatoid arthritis (implicated_via_orthology)	NCF1 NCF1B	2.40e-03	12	182	2	DOID:7148 (implicated_via_orthology)
Disease	Extrapyramidal Disorders	CYP2D6 XPR1	2.40e-03	12	182	2	C0015371
Disease	hair colour measurement, hair morphology measurement	NPLOC4 HERC2	2.40e-03	12	182	2	EFO_0007821, EFO_0007822
Disease	Basal Ganglia Diseases	CYP2D6 XPR1	2.40e-03	12	182	2	C0004782
Disease	Uterine leiomyoma	ITGA11 SYNE1 PDHX PLEKHM3	2.47e-03	91	182	4	HP_0000131
Disease	FVC change measurement, response to placebo	KIF1A KATNIP	2.82e-03	13	182	2	EFO_0008344, EFO_0010339
Disease	bone density	PSG1 MB TACC2 PDHX SLC8A1 CTNNBL1 LRP5 MYO15A	2.93e-03	388	182	8	EFO_0003923
Disease	Adenocarcinoma of large intestine	PHKG1 DCLK3 PAK3 PRKDC	2.99e-03	96	182	4	C1319315
Disease	Spastic Paraplegia, Hereditary	PNPLA6 CYP2U1	3.28e-03	14	182	2	C0037773
Disease	early cardiac repolarization measurement	SLC9A8 LRP5	3.28e-03	14	182	2	EFO_0004885
Disease	rectum cancer, overall survival	DIP2C IQCM	3.77e-03	15	182	2	EFO_0000638, EFO_1000657
Disease	suntan	MYH7B PIGU DCT HERC2	3.85e-03	103	182	4	EFO_0004279
Disease	Peripheral Nervous System Diseases	ERCC1 DAPK1 PNPLA6	4.54e-03	54	182	3	C4721453
Disease	cardiac troponin I measurement	ITGA11 FSTL5 TMTC2 PIGU PZP	4.81e-03	176	182	5	EFO_0010071
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TRIO ATP2B1	4.84e-03	17	182	2	DOID:0060307 (is_implicated_in)
Disease	gamma-aminoisobutyric acid measurement	TACC2 ADGRL4	6.04e-03	19	182	2	EFO_0010482
Disease	ovulation	RLBP1 ACSL1	6.04e-03	19	182	2	GO_0030728
Disease	response to methotrexate, neurotoxicity	DCT PNPLA6	6.04e-03	19	182	2	EFO_0011057, GO_0031427
Disease	cholesterol in chylomicrons and extremely large VLDL measurement	DCT PRKAG3 DOCK7	6.10e-03	60	182	3	EFO_0021898

Protein segments in the cluster

Peptide	Gene	Start	Entry
FLTLFFLAPELHPKK	URB2	1181	Q14146
FALPLKTEHKQFLVR	PPP2R5B	266	Q15173
GFALPLKAEHKQFLV	PPP2R5E	251	Q16537
VIIYKVFRHTAGLKP	ADGRL4	591	Q9HBW9
IAGFLDPEKKLFSHR	CTDP1	256	Q9Y5B0
PHKLEVGAKLDLFGR	FBRSL1	616	Q9HCM7
RIKIIDFGLAHKIDF	DAPK1	156	P53355
FKVTEGKLLRDPLSH	CDY2A	176	Q9Y6F7
HITLELIKGKLVFFL	CNTNAP3	231	Q9BZ76
FPKILGVLTHLDSFK	AGAP9	71	Q5VTM2
VFLFEHLLLFSKLKG	ARHGEF40	1291	Q8TER5
SFLKRNKHGPFLLFV	ARSL	281	P51690
HIFKGIKIFPTVLTF	CATSPERB	346	Q9H7T0
HKFVDILGLRTIFPL	CTNNBL1	371	Q8WYA6
KALAKLEHPGIVRYF	EIF2AK3	641	Q9NZJ5
ILTHKRLLKFLHIFG	PRKAG3	321	Q9UGI9
FRKKVSPAVLVHRDG	BTN1A1	66	Q13410
AELGTFPRAFKKLLH	BLOC1S4	161	Q9NUP1
AIIPAFHFLKSEKGL	ADGB	1166	Q8N7X0
SFNVFLKIKDILPRH	ALG6	281	Q9Y672
KGILVGESRSFKPHL	AKAP7	206	Q9P0M2
PNGTLKIIDRKKHIF	ACSL1	546	P33121
LGFVHSPLLKRKQRT	ARSI	326	Q5FYB1
EGIFLHVTVPRKIKS	ADAM18	21	Q9Y3Q7
DRFLAIVHPVKSLKL	GPR17	156	Q13304
SAKFEGKPLLQRHRL	BOLA2	41	Q9H3K6
IPAFRTFLKRHDKTI	ECT2L	681	Q008S8
HQLGRKLPDFLTAKL	API5	351	Q9BZZ5
HRDKKGFTPLILAAT	ANKRD17	1111	O75179
GVLRINPKKFHEAFI	DIS3L2	71	Q8IYB7
VERGLTLHLKFLEPF	C1R	226	P00736
IPTSRLKFLKEAGHG	ATP2B1	1061	P20020
FIGIDLVKDHLKRTP	ETNPPL	366	Q8TBG4
KFKGVFHPVIISPDR	AOX1	276	Q06278
LKFVKVDSHFRQGIP	PZP	346	P20742
LDSKVKRIGPHIEIF	IQCM	261	A0A1B0GVH7
AHVKIADFGLAKLLP	JAK3	961	P52333
KFILAFAIPDKPRHI	ANO10	606	Q9NW15
PFLFLDSLHKKAGGR	MORN1	381	Q5T089
HPGKFTLFIRQRKGF	MOGAT1	196	Q96PD6
RRGSAKELLQHPFLK	PAK3	521	O75914
EVSKEARKRFLGPLH	PNPLA2	71	Q96AD5
KNVRVLGHFEKPLFL	PNPLA6	191	Q8IY17
FKSFGELVHKPLLVD	MAP4K4	1061	O95819
LGLSAHPKLEKTFFV	OR13C6P	16	Q8NH95
LGLSAHPKLEKTFFV	OR13C7	16	P0DN81
PFTIHDLRGLGAKKF	MICAL3	131	Q7RTP6
KLEENLHKLGTFPFR	HOGA1	56	Q86XE5
EFPLGRFHTKKDIKA	MATN1	326	P21941
KKHFIFGEPRKLITQ	MAGEB3	236	O15480
LEKRTLILTHFPKFL	KAT2B	336	Q92831
VSIFKLILRFMGDPH	MYO15A	2086	Q9UKN7
FGLDKHLIILPFKRR	GPR155	711	Q7Z3F1
RGGKQLLHSPFFKVL	HERC2	3836	O95714
AKTPHRGVKEFGLLV	KATNIP	1506	O60303
PHTVRILELLKLKFG	DOP1B	2201	Q9Y3R5
CLVFSLIGLHFKIKP	MAGOH	131	P61326
KVLRKLTVNGFVEPH	IPO11	216	Q9UI26
LGFPLDLQKKLLHFT	HECTD2	696	Q5U5R9
KRRTLLEDKLPHIFG	LRP5	536	O75197
PAKGKLFLHRVGRVA	DDX54	416	Q8TDD1
KLADFGLAKHVVRPI	DCLK3	496	Q9C098
QLEHIFPREGIFKKL	FSIP2	2826	Q5CZC0
KARRLFDVLHEPFLK	ERCC1	281	P07992
FIPREVGEHLVSIKK	FLNB	1966	O75369
KFIRIHFGPSGKLAS	MYH7B	291	A7E2Y1
KVAFVLGRHKVRTAP	PER1	451	O15534
VKKEHIPGTLRFRLS	PDHX	171	O00330
RPTLLHLIHGKVKEF	MTTP	121	P55157
SRAPKGSLRKFLEHL	PFKP	6	Q01813
IRHIALLGFEKRFVP	NCF1	6	P14598
GIPAKSHRGEKLLLF	PIP5K1B	331	O14986
LLFGDFESPLHKLRK	EBLN2	256	Q6P2I7
LLKIKHGDLLFLFPS	NPLOC4	66	Q8TAT6
AFKISKEVLAGRPLF	HNRNPU	431	Q00839
HKLDFGLKPEFLSRP	AUTS2	676	Q8WXX7
IAIKELFAGKPVLRH	NIPA2	201	Q8N8Q9
HPKGIISRRDVEKFL	LRRK2	1621	Q5S007
LGKLISIHIKVDPLF	GCN1	2371	Q92616
IFHGFRGSILKTPKQ	ITGA11	576	Q9UKX5
PKIFGGEIKTHILLF	P4HB	246	P07237
GEIKTHILLFLPKSV	P4HB	251	P07237
ELKKQGFLLREHFTP	PARP4	221	Q9UKK3
LAPFLGKVIKFATSH	PLEKHM3	656	Q6ZWE6
GRKGLFPFTHVKIFD	CRKL	281	P46109
FTTPGHLLDKFIKEF	OAS2	341	P29728
FLKKGLVNDLARVPH	HUWE1	2216	Q7Z6Z7
TIPLAIKLKEHPIFF	PIGU	301	Q9H490
KNVRVLGHFEKPLFL	PNPLA7	141	Q6ZV29
LTKIVPLFHFVSLEK	LRRIQ1	1071	Q96JM4
IRHIALLGFEKRFVP	NCF1B	6	A6NI72
EFQRHIKPSEKLLGF	FSTL5	471	Q8N475
SGHFREKLFPLFLSI	MEI1	216	Q5TIA1
EKEKKSPVGLHFLFL	GPRC5B	86	Q9NZH0
GLRFTVPHLRDTKKT	ITGA5	746	P08648
FHKALFSPSRIIKEG	PXDNL	1081	A1KZ92
RHFGLGKLSLEPKII	CYP2U1	186	Q7Z449
LLLLFKLVAPVTFRH	CPN1	11	P15169
TGRLPTKKLFHEELA	DOCK7	976	Q96N67
LNIGLFPKDVTHFLK	CYP3A43	236	Q9HB55
HLPRIVSYIEKGLFK	SDR42E1	196	Q8WUS8
LHIPALAGKVLRFQK	CYP2D6	231	P10635
HRIKKLFGFIPGSED	CALHM4	246	Q5JW98
IVPASRFKLLKGAEH	CENPV	186	Q7Z7K6
PKHVLFQRFAKIFIG	DPY19L4	41	Q7Z388
KLFKDLGLHPRAVST	DIP2C	1281	Q9Y2E4
FIKNHAFRLLKPGGV	GAMT	151	Q14353
LKHVLGAIFSKIFGP	HS6ST2	126	Q96MM7
HGFFLPEKISSTLKV	ELP4	201	Q96EB1
KTFSFAIPLIEKLHG	DDX21	236	Q9NR30
FLLETGDIAFHIKPR	GRIFIN	36	A4D1Z8
GVTFPIFHKIKILGS	GPX8	131	Q8TED1
LFKPNFGASLHILKV	GALC	86	P54803
TSLEKHKLFISGLPF	SART3	796	Q15020
LAEKIKPGLHSFIFG	C9orf72	451	Q96LT7
HITLELIKGKLVFFL	CNTNAP3B	231	Q96NU0
PFGSKKKRLLSVHDF	MLPH	181	Q9BV36
KFQLPGQKLFIRHIT	PSG1	371	P11464
RVSPIVSKKGYLHFL	KIF1A	1571	Q12756
PFTIHDLRGLGAKKF	MICAL2	131	O94851
HREVPGSKRSFLKLI	PTPRK	1341	Q15262
TGHFKPLEKKFVRVS	PCGF6	266	Q9BYE7
VRHFSPRGKFKVIAL	PHKG1	296	Q16816
ILKSHISGIFRPKFS	FES	426	P07332
LKIFEGIKHPNLVRY	MAP3K4	1391	Q9Y6R4
HALVADGLKPFRKDL	RUSC1	536	Q9BVN2
RLKPKHTKLFVFLAV	TMEM106A	86	Q96A25
LIKIFHSLGPEKFPL	SYN3	211	O14994
RFLGRFGLQPHKTKL	TRMT2A	91	Q8IZ69
PSGFRKFLVHNVKEL	RPL32	71	P62910
ELLFDGIKKHRVTLP	URM1	16	Q9BTM9
AFKVLHDKQRGPLVF	GFM2	371	Q969S9
FRKHTKLLIVGVFLL	SLC6A16	531	Q9GZN6
KRHQLGKNFFEPTLL	ALDH5A1	411	P51649
LKHGFLEEFITPIVK	TOP2B	586	Q02880
KIIKEHRVFFSDKGP	SYNE1	1056	Q8NF91
FTLKEKGHLLRLPAA	TEDC2	196	Q7L2K0
FLTLHGGKKAPFRIQ	FER1L5	436	A0AVI2
KPSGVHLKLVLRFSD	FAM20A	216	Q96MK3
PAKHAGEILKFLGRE	SLITRK2	561	Q9H156
VKPRKDAHLFSIGAI	SIPA1L2	841	Q9P2F8
LKHIDLRKTPSLEFG	SLC9A8	286	Q9Y2E8
RKIHLFDIDVPGKIT	NIT2	111	Q9NQR4
KDFVLKYALPLVGHR	PDIA4	386	P13667
VFHPFLDEILIGKIK	POLR3H	76	Q9Y535
VVLFVLLQPKLKSFH	SUSD6	136	Q92537
FHLLPSSVKFGVLKE	SPAG17	2076	Q6Q759
VKPSGHLFFRKLGNL	BROX	301	Q5VW32
KGRKPFLLAAERGHV	ANKDD1B	201	A6NHY2
PAGTLKIIDRKKHIF	ACSL6	546	Q9UKU0
IEHRDKKGFTPLILA	ANKHD1	1081	Q8IWZ3
GTIFAELATKKPLFH	CDK1	191	P06493
HRVAGIFPRLSFKDK	CLPTM1	446	O96005
RIHLTPDFIAGKKLA	CLCA1	131	A8K7I4
PFLKEKTRKRIFLHG	CLVS2	216	Q5SYC1
AILKFFHKVRAGQPL	TBC1D24	246	Q9ULP9
KLLFRVFTAPFHKVG	XPR1	376	Q9UBH6
LKEAVILPIKFPHLF	VPS4B	146	O75351
TTLPKFREVGHLLKE	WNT7B	216	P56706
SIVKYFKERLHLPIG	CTPS2	261	Q9NRF8
FLRKKVSEAHLPSGI	TULP2	76	O00295
GRFIKSHVIKLSPDE	TMPRSS11F	106	Q6ZWK6
RGHLVLKSFKDTPLE	TMEM143	246	Q96AN5
KGHEFSIPYVELKIR	TNN	1261	Q9UQP3
GFKKLHGRSFDDPIV	HSPA4L	66	O95757
TILELARYFLKHGPK	REXO5	371	Q96IC2
VFVFHRLKIKQILPT	TMTC2	201	Q8N394
VLASSKGRKVPRHFL	THEMIS2	301	Q5TEJ8
ITFLKPGVFEDLHRL	RXFP1	186	Q9HBX9
HIAKIFEKPVLGALA	TACC2	1411	O95359
PFLKSKLLERVFVHG	RLBP1	256	P12271
FLGALDLAKKRVHPD	DCT	141	P40126
LAKEIGDAKFLHFLP	TLR7	326	Q9NYK1
IRLFKGHPETLEKFD	MB	31	P02144
AVFFLLPKFHGVLKT	PRKDC	2381	P78527
RHPGVIFKALKALSD	ZFYVE1	391	Q9HBF4
SLGITEFLRKKEIHP	ZNF839	441	A8K0R7
SLFRGLPNLITHKKF	ZNF800	76	Q2TB10
KRFGLPFVLHLEKTI	USP31	471	Q70CQ4
HIRGSPFKLKVIRSA	TRIM2	411	Q9C040
TAKVPIVKFFHLRSG	TUT7	1101	Q5VYS8
FQSKIHSRIGSFLKP	TIGD7	516	Q6NT04
GALFVEKFIEKPRHI	PC	231	P11498
EALQFVPKRKHTGFL	TRMT10C	371	Q7L0Y3
KNLRKTRELFVHGLP	SLFN5	566	Q08AF3
KGEKRAVSFHRFPLK	THAP4	16	Q8WY91
RGLPALRHVFDKAKF	TIPIN	76	Q9BVW5
GLFIRKPFIKFICHT	TRPC4	356	Q9UBN4
PEKLGSLFVKHERRL	TRIO	2041	O75962
PSLVILGHYFKKRLG	SLC16A10	186	Q8TF71
LEHPNVLKFIGVLYK	LIMK1	391	P53667
PDGETRKIKHLRVFF	SLC8A1	191	P32418