Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

6.07e-1146306GO:0030020
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

9.94e-09188307GO:0005201
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2

1.31e-054302GO:0005219
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

HCN4 RYR1 RYR2

1.62e-0533303GO:0005217
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2

3.26e-056302GO:0048763
GeneOntologyMolecularFunctionstructural molecule activity

COL2A1 MRPS15 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

3.71e-05891308GO:0005198
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR2

3.29e-0418302GO:0015278
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR2

9.88e-0431302GO:0099604
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

HCN4 RYR1 RYR2

1.19e-03140303GO:0099094
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

HCN4 RYR1 RYR2

2.98e-03193303GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

HCN4 RYR1 RYR2

3.16e-03197303GO:0022834
GeneOntologyMolecularFunctionlyase activity

XRCC5 GUCY2F NEIL2

3.88e-03212303GO:0016829
GeneOntologyMolecularFunctionDNA helicase activity

XRCC5 SUPV3L1

3.90e-0362302GO:0003678
GeneOntologyBiologicalProcesscollagen-activated tyrosine kinase receptor signaling pathway

COL4A2 COL4A3 COL4A6

5.45e-0712293GO:0038063
GeneOntologyBiologicalProcesscollagen-activated signaling pathway

COL4A2 COL4A3 COL4A6

2.01e-0618293GO:0038065
GeneOntologyBiologicalProcessoocyte growth

KMT2D FOXL2

1.14e-054292GO:0001555
GeneOntologyBiologicalProcessextracellular matrix organization

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

1.19e-05377296GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

1.21e-05378296GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

1.23e-05379296GO:0045229
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

HCN4 RYR2

8.53e-0510292GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

HCN4 RYR2

8.53e-0510292GO:0086015
GeneOntologyBiologicalProcessglomerular basement membrane development

COL4A3 COL4A4

8.53e-0510292GO:0032836
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

HCN4 RYR2

1.04e-0411292GO:0086070
GeneOntologyBiologicalProcesscellular response to caffeine

RYR1 RYR2

1.04e-0411292GO:0071313
GeneOntologyBiologicalProcesscirculatory system development

COL2A1 COL4A2 COL4A3 BCOR HCN4 COL27A1 RYR1 RYR2 CEMIP2

1.08e-041442299GO:0072359
GeneOntologyBiologicalProcesscellular response to purine-containing compound

RYR1 RYR2

1.72e-0414292GO:0071415
GeneOntologyBiologicalProcessanimal organ morphogenesis

COL2A1 DLG5 FOXL2 BCOR AHDC1 COL27A1 RYR1 RYR2

2.69e-041269298GO:0009887
GeneOntologyBiologicalProcessresponse to caffeine

RYR1 RYR2

3.94e-0421292GO:0031000
GeneOntologyBiologicalProcessnotochord development

COL2A1 COL27A1

5.17e-0424292GO:0030903
GeneOntologyBiologicalProcessembryo development

COL2A1 KMT2D FOXL2 BCOR HCN4 AHDC1 COL27A1 RYR2

6.23e-041437298GO:0009790
GeneOntologyBiologicalProcessregulation of cardiac muscle cell action potential

HCN4 RYR2

8.10e-0430292GO:0098901
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

HCN4 RYR2

1.04e-0334292GO:0086019
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

RYR1 RYR2

1.23e-0337292GO:0014808
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

RYR1 RYR2

1.37e-0339292GO:1903514
GeneOntologyBiologicalProcesscellular response to alkaloid

RYR1 RYR2

1.44e-0340292GO:0071312
GeneOntologyCellularComponentcomplex of collagen trimers

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

2.74e-1321306GO:0098644
GeneOntologyCellularComponentcollagen type IV trimer

COL4A2 COL4A3 COL4A4 COL4A6

5.16e-116304GO:0005587
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A2 COL4A3 COL4A4 COL4A6

2.40e-108304GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A2 COL4A3 COL4A4 COL4A6

2.40e-108304GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A2 COL4A3 COL4A4 COL4A6

2.40e-108304GO:0098645
GeneOntologyCellularComponentcollagen trimer

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

2.56e-0988306GO:0005581
GeneOntologyCellularComponentbasement membrane

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

7.91e-07122305GO:0005604
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

6.60e-06332306GO:0005788
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

7.94e-06530307GO:0062023
GeneOntologyCellularComponentextracellular matrix

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

3.15e-05656307GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

3.21e-05658307GO:0030312
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

RYR1 RYR2

8.90e-0510302GO:0014701
GeneOntologyCellularComponentfibrillar collagen trimer

COL2A1 COL27A1

1.30e-0412302GO:0005583
GeneOntologyCellularComponentbanded collagen fibril

COL2A1 COL27A1

1.30e-0412302GO:0098643
GeneOntologyCellularComponentsupramolecular polymer

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1 RYR1 RYR2

2.01e-041187308GO:0099081
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 RYR2

1.90e-0345302GO:0033017
GeneOntologyCellularComponentsmooth endoplasmic reticulum

RYR1 RYR2

1.98e-0346302GO:0005790
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

NPHS2 RYR1 RYR2

2.32e-03185303GO:0009898
GeneOntologyCellularComponentextrinsic component of cytoplasmic side of plasma membrane

RYR1 RYR2

2.92e-0356302GO:0031234
GeneOntologyCellularComponentcytoplasmic side of membrane

NPHS2 RYR1 RYR2

4.29e-03230303GO:0098562
GeneOntologyCellularComponentcation channel complex

HCN4 RYR1 RYR2

4.55e-03235303GO:0034703
GeneOntologyCellularComponentcalcium channel complex

RYR1 RYR2

4.91e-0373302GO:0034704
GeneOntologyCellularComponentsarcoplasmic reticulum

RYR1 RYR2

7.06e-0388302GO:0016529
HumanPhenoLenticonus

COL4A3 COL4A4 COL4A6

4.38e-0610183HP:0001142
HumanPhenoAbnormality of lens shape

COL4A3 COL4A4 COL4A6

2.93e-0518183HP:0011526
HumanPhenoGlomerular basement membrane lamellation

COL4A3 COL4A4

3.53e-053182HP:0030034
HumanPhenoAnterior lenticonus

COL4A4 COL4A6

3.53e-053182HP:0011501
HumanPhenoThin glomerular basement membrane

COL4A3 COL4A4

3.53e-053182HP:0012577
MousePhenokidney hemorrhage

COL2A1 COL4A3 NPHS2

2.05e-0614263MP:0000533
MousePhenoglomerular crescent

COL4A3 COL4A4 NPHS2

5.43e-0619263MP:0011506
MousePhenoabnormal fetal growth/weight/body size

COL2A1 XRCC5 AHDC1 COL27A1 RYR1 RYR2

1.86e-05312266MP:0004197
MousePhenorenal cast

COL4A3 COL4A4 NPHS2

3.29e-0534263MP:0011402
MousePhenopodocyte foot process effacement

COL4A3 COL4A4 NPHS2

4.61e-0538263MP:0008140
MousePhenoretrognathia

COL2A1 COL27A1

6.95e-057262MP:0004282
MousePhenopodocyte hypertrophy

COL4A4 NPHS2

6.95e-057262MP:0011871
MousePhenopodocyte microvillus transformation

COL4A3 NPHS2

6.95e-057262MP:0011868
MousePhenoabnormal renal glomerulus basement membrane morphology

COL4A3 COL4A4 NPHS2

7.19e-0544263MP:0011348
MousePhenokidney failure

COL4A3 COL4A4 NPHS2

8.22e-0546263MP:0003606
MousePhenoexpanded mesangial matrix

COL4A3 COL4A4 NPHS2

8.22e-0546263MP:0011353
MousePhenoabnormal mesangial matrix morphology

COL4A3 COL4A4 NPHS2

1.12e-0451263MP:0011338
MousePhenoabnormal podocyte foot process morphology

COL4A3 COL4A4 NPHS2

1.41e-0455263MP:0008059
MousePhenoalbuminuria

COL4A3 COL4A4 NPHS2

2.11e-0463263MP:0002871
MousePhenoglomerulosclerosis

COL4A3 COL4A4 NPHS2

2.64e-0468263MP:0005264
MousePhenoabnormal podocyte morphology

COL4A3 COL4A4 NPHS2

2.88e-0470263MP:0005326
MousePhenoabnormal glomerular capsule visceral layer morphology

COL4A3 COL4A4 NPHS2

2.88e-0470263MP:0011497
MousePhenoaorta stenosis

COL4A2 XRCC5

4.45e-0417262MP:0010463
MousePhenoabnormal glomerular mesangium morphology

COL4A3 COL4A4 NPHS2

4.76e-0483263MP:0011339
MousePhenochondrodystrophy

COL2A1 COL27A1

5.00e-0418262MP:0002657
MousePhenodomed cranium

COL2A1 COL27A1 RYR1

5.10e-0485263MP:0000440
MousePhenocraniofacial phenotype

COL2A1 COL4A2 DLG5 KMT2D XRCC5 AHDC1 SUPV3L1 COL27A1 RYR1

5.48e-041372269MP:0005382
MousePhenoabnormal craniofacial morphology

COL2A1 COL4A2 DLG5 KMT2D XRCC5 AHDC1 SUPV3L1 COL27A1 RYR1

5.48e-041372269MP:0000428
MousePhenohematuria

COL4A3 COL4A4

5.58e-0419262MP:0005161
MousePhenoabnormal blood urea nitrogen level

COL4A3 COL4A4 DLG5 NPHS2 NEIL2

6.60e-04389265MP:0005265
MousePhenoabnormal blood circulation

COL2A1 COL4A2 COL4A3 DLG5 NPHS2 XRCC5 COL27A1

6.86e-04845267MP:0002128
MousePhenoabnormal head morphology

COL2A1 COL4A2 DLG5 KMT2D BCOR AHDC1 COL27A1 RYR1

7.00e-041120268MP:0000432
MousePhenoabnormal renal tubule morphology

COL4A3 COL4A4 DLG5 NPHS2

7.64e-04227264MP:0002703
MousePhenoabnormal sarcoplasmic reticulum morphology

RYR1 RYR2

8.22e-0423262MP:0004088
MousePhenoabnormal renal glomerular capsule morphology

COL4A3 COL4A4 NPHS2

9.97e-04107263MP:0002828
MousePhenoincreased renal glomerulus basement membrane thickness

COL4A3 COL4A4

1.13e-0327262MP:0011409
MousePhenohemorrhage

COL2A1 COL4A2 COL4A3 DLG5 NPHS2 COL27A1

1.14e-03664266MP:0001914
MousePhenoabnormal artery morphology

COL4A2 PON2 NPHS2 XRCC5 RYR1

1.15e-03440265MP:0002191
DomainC4

COL4A2 COL4A3 COL4A4 COL4A6

8.09e-116304SM00111
Domain-

COL4A2 COL4A3 COL4A4 COL4A6

8.09e-1163042.170.240.10
DomainCollagen_VI_NC

COL4A2 COL4A3 COL4A4 COL4A6

8.09e-116304IPR001442
DomainNC1_IV

COL4A2 COL4A3 COL4A4 COL4A6

8.09e-116304PS51403
DomainC4

COL4A2 COL4A3 COL4A4 COL4A6

8.09e-116304PF01413
DomainCollagen

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

4.04e-0985306PF01391
DomainCollagen

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

4.04e-0985306IPR008160
DomainRyR

RYR1 RYR2

7.48e-063302PF02026
DomainRyanodine_rcpt

RYR1 RYR2

7.48e-063302IPR003032
DomainRR_TM4-6

RYR1 RYR2

7.48e-063302PF06459
DomainRyanrecept_TM4-6

RYR1 RYR2

7.48e-063302IPR009460
DomainRyan_recept

RYR1 RYR2

7.48e-063302IPR013333
DomainCTDL_fold

COL4A2 COL4A3 COL4A4 COL4A6

2.49e-05107304IPR016187
DomainRIH_assoc

RYR1 RYR2

3.73e-056302PF08454
DomainRIH_assoc-dom

RYR1 RYR2

3.73e-056302IPR013662
DomainRYDR_ITPR

RYR1 RYR2

3.73e-056302PF01365
DomainRIH_dom

RYR1 RYR2

3.73e-056302IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2

3.73e-056302IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2

3.73e-056302IPR015925
DomainIns145_P3_rec

RYR1 RYR2

3.73e-056302PF08709
Domain-

RYR1 RYR2

3.73e-0563021.25.10.30
DomainMIR

RYR1 RYR2

1.11e-0410302PS50919
DomainMIR

RYR1 RYR2

1.11e-0410302PF02815
DomainMIR

RYR1 RYR2

1.11e-0410302SM00472
DomainMIR_motif

RYR1 RYR2

1.11e-0410302IPR016093
DomainNC1_FIB

COL2A1 COL27A1

1.36e-0411302PS51461
DomainFib_collagen_C

COL2A1 COL27A1

1.36e-0411302IPR000885
DomainFib_collagen_C

COL2A1 COL27A1

1.36e-0411302PD002078
DomainCOLFI

COL2A1 COL27A1

1.36e-0411302SM00038
DomainCOLFI

COL2A1 COL27A1

1.36e-0411302PF01410
DomainIon_trans_dom

HCN4 RYR1 RYR2

7.97e-04114303IPR005821
DomainIon_trans

HCN4 RYR1 RYR2

7.97e-04114303PF00520
DomainEF-hand_8

RYR1 RYR2

1.36e-0334302PF13833
DomainConA-like_dom

COL27A1 RYR1 RYR2

5.11e-03219303IPR013320
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

1.83e-1044276M27812
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

1.41e-0961276M27103
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

2.22e-0910274M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

2.22e-0910274MM1560
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

2.51e-0967276M26999
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

3.39e-0932275MM14924
PathwayBIOCARTA_VITCB_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

3.49e-0911274M15422
PathwayBIOCARTA_VITCB_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

5.23e-0912274MM1526
PathwayBIOCARTA_ACE2_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

7.54e-0913274MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

7.54e-0913274M12950
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

1.05e-0814274MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

1.05e-0814274M6487
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

1.25e-0841275MM15538
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A2 COL4A3 COL4A4 COL4A6

1.44e-0815274M27161
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A2 COL4A3 COL4A4 COL4A6

1.44e-0815274MM14922
PathwayREACTOME_COLLAGEN_FORMATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

1.52e-0890276M631
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 COL4A3 COL4A4 COL4A6

3.21e-0818274M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 COL4A3 COL4A4 COL4A6

3.21e-0818274MM14882
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

3.48e-0850275MM14796
PathwayREACTOME_COLLAGEN_DEGRADATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

4.69e-0853275MM14566
PathwayBIOCARTA_AMI_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

5.06e-0820274M15394
PathwayREACTOME_NCAM1_INTERACTIONS

COL2A1 COL4A2 COL4A3 COL4A4

5.06e-0820274MM15061
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

8.13e-0859275M27218
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

9.22e-0823274M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A2 COL4A3 COL4A4 COL4A6

9.22e-0823274MM1427
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

9.63e-0861275MM14637
PathwayREACTOME_COLLAGEN_DEGRADATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

1.23e-0764275M26953
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A2 COL4A3 COL4A4 COL4A6

2.83e-0730274M27216
PathwayREACTOME_COLLAGEN_FORMATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

2.93e-0776275MM14573
PathwayREACTOME_ECM_PROTEOGLYCANS

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

2.93e-0776275M27219
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

2.93e-0776275MM14867
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

5.15e-0785275M16441
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL2A1 COL4A2 COL4A3 COL4A4

7.53e-0738274MM14969
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

1.14e-06300277M610
PathwayREACTOME_NCAM1_INTERACTIONS

COL2A1 COL4A2 COL4A3 COL4A4

1.14e-0642274M7169
PathwayPID_SYNDECAN_1_PATHWAY

COL2A1 COL4A3 COL4A4 COL4A6

1.65e-0646274M198
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

2.22e-06114275MM14571
PathwayREACTOME_SIGNALING_BY_PDGF

COL2A1 COL4A2 COL4A3 COL4A4

3.93e-0657274MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

COL2A1 COL4A2 COL4A3 COL4A4

4.22e-0658274M2049
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL2A1 COL4A2 COL4A3 COL4A4

5.88e-0663274M11187
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

6.09e-06140275M587
PathwayPID_INTEGRIN1_PATHWAY

COL2A1 COL4A3 COL4A4 COL4A6

7.09e-0666274M18
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3

7.60e-06258276MM14572
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL2A1 COL4A3 COL4A4 COL4A6

1.12e-0574274M160
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL2A1 COL4A2 COL4A4 COL4A6

1.85e-0584274M7098
PathwayWP_SMALL_CELL_LUNG_CANCER

COL4A2 COL4A3 COL4A4 COL4A6

3.14e-0596274M39834
PathwayPID_INTEGRIN3_PATHWAY

COL4A3 COL4A4 COL4A6

7.35e-0543273M53
PathwayWP_NEPHROTIC_SYNDROME

COL4A3 COL4A4 NPHS2

8.43e-0545273M39864
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR1 RYR2

1.92e-0411272M47958
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

COL4A2 COL4A3 COL4A4 COL4A6

2.34e-04161274M39770
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR1 RYR2

2.72e-0413272M39589
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

COL4A3 COL4A4 NPHS2

3.42e-0472273M39403
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

COL4A3 COL4A4 NPHS2

3.56e-0473273MM15906
PathwayWP_PI3KAKT_SIGNALING

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

4.08e-04339275M39736
PathwayWP_FOCAL_ADHESION

COL2A1 COL4A2 COL4A4 COL4A6

4.14e-04187274MM15913
PathwayKEGG_FOCAL_ADHESION

COL2A1 COL4A2 COL4A4 COL4A6

5.24e-04199274M7253
PathwayWP_FOCAL_ADHESION

COL2A1 COL4A2 COL4A4 COL4A6

5.24e-04199274M39402
PathwayKEGG_SMALL_CELL_LUNG_CANCER

COL4A2 COL4A4 COL4A6

5.38e-0484273M3228
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR1 RYR2

5.92e-0419272M47760
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

COL2A1 COL4A2 COL4A3 COL4A4

1.44e-03261274MM15676
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

COL2A1 COL27A1

1.49e-0330272M27772
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

COL2A1 COL4A2 COL4A4 COL4A6

2.46e-03302274M39719
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

COL2A1 COL27A1

2.77e-0341272M27778
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

COL2A1 COL4A2 COL4A3 COL4A4 COL27A1

3.04e-03532275M27870
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

COL2A1 COL4A2 COL4A4 COL4A6

3.24e-03326274MM15917
PathwayWP_15Q25_COPY_NUMBER_VARIATION

RYR1 RYR2

3.47e-0346272M48105
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2

4.75e-0354272MM15202
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2

4.75e-0354272M27460
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

COL2A1 COL4A2 COL4A3 COL4A4

7.79e-03418274MM15587
PathwayWP_PLEURAL_MESOTHELIOMA

COL4A2 COL4A3 COL4A4 COL4A6

9.23e-03439274M42563
PathwayREACTOME_SIGNALING_BY_MET

COL2A1 COL27A1

9.94e-0379272M27643
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

1.88e-14830510382266
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

1.88e-1483053997552
Pubmed

In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine.

COL2A1 COL4A2 COL4A3 COL4A4

2.25e-1253049409248
Pubmed

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

3.88e-121930515689378
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-12630410534397
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-1263049506531
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-1263049673377
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-1263042426947
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-12630423551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-1263046811420
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-12630411732842
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-12630419275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-1263046988303
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-1263046389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A2 COL4A3 COL4A4 COL4A6

6.74e-12630412225806
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A2 COL4A3 COL4A4 COL4A6

1.57e-11730411711546
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A2 COL4A3 COL4A4 COL4A6

1.57e-1173048006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A2 COL4A3 COL4A4 COL4A6

1.57e-11730410416788
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A2 COL4A3 COL4A4 COL4A6

1.57e-1173041724753
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A2 COL4A3 COL4A4 COL4A6

3.14e-11830429422532
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A2 COL4A3 COL4A4 COL4A6

5.65e-1193049878537
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A2 COL4A3 COL4A4 COL4A6

5.65e-11930412101409
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A2 COL4A3 COL4A4 COL4A6

9.41e-11103049136074
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A2 COL4A3 COL4A4 COL4A6

1.48e-101130414998921
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A2 COL4A3 COL4A4 COL4A6

1.48e-10113047500359
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A2 COL4A3 COL4A4 COL4A6

2.22e-101230415837576
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A2 COL4A3 COL4A4 COL4A6

2.22e-101230412180907
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A2 COL4A3 COL4A4 COL4A6

2.22e-101230416024816
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A2 COL4A3 COL4A4 COL4A6

4.47e-101430412878203
Pubmed

Collagen types in various layers of the human aorta and their changes with the atherosclerotic process.

COL4A2 COL4A3 COL4A4

5.79e-1033033089234
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A2 COL4A3 COL4A4 COL4A6

8.12e-101630415878328
Pubmed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

COL2A1 COL4A2 COL4A3 COL4A6 COL27A1

2.10e-096230528344315
Pubmed

Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.

COL4A2 COL4A3 COL4A4

2.32e-0943037827955
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

COL4A2 COL4A3 COL4A4 COL4A6

6.63e-092630424742657
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

8.00e-0917530628071719
Pubmed

HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.

COL4A2 COL4A3 COL4A4

1.16e-0863037495302
Pubmed

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.

COL4A2 COL4A3 COL4A4 COL4A6

1.39e-083130422925884
Pubmed

Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.

COL4A2 COL4A3 COL4A4

2.02e-08730310639489
Pubmed

Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.

COL4A2 COL4A3 COL4A4

2.02e-0873037521231
Pubmed

Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).

COL4A2 COL4A3 COL4A4

2.02e-08730310716744
Pubmed

Large-scale identification of genes implicated in kidney glomerulus development and function.

COL4A2 COL4A3 COL4A4 NPHS2

2.05e-083430416498405
Pubmed

Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling.

COL4A2 COL4A3 COL4A4

3.23e-08830311683410
Pubmed

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.

COL4A2 COL4A3 COL4A6

3.23e-08830310970885
Pubmed

Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.

COL4A2 COL4A3 COL4A6

3.23e-0883031377218
Pubmed

Molecular properties of wild-type and mutant betaIG-H3 proteins.

COL4A2 COL4A3 COL4A4

3.23e-08830311867580
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

COL4A2 COL4A3 COL4A4 COL4A6

4.02e-084030427068110
Pubmed

Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.

COL4A2 COL4A3 COL4A4

4.85e-0893038562707
Pubmed

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.

COL4A2 COL4A3 COL4A4

4.85e-08930310880400
Pubmed

Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.

COL4A2 COL4A3 COL4A4

4.85e-0893038995276
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

COL4A2 COL4A3 COL4A4

6.92e-08103039415455
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A2 COL4A3 COL4A4

9.51e-08113039731539
Pubmed

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

COL4A2 COL4A3 COL4A4

1.27e-07123038918877
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

COL4A2 COL4A3 COL4A4

1.65e-07133039833687
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3

2.01e-0715330525037231
Pubmed

Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.

COL4A2 COL4A4 COL4A6

2.09e-071430319858219
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

COL4A2 COL4A3 COL4A4

2.62e-071530310625553
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

COL4A2 COL4A3 COL4A4

2.62e-07153039264260
Pubmed

Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.

COL4A2 COL4A3 COL4A4

2.62e-071530310706142
Pubmed

Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.

COL4A3 COL4A4 NPHS2

3.91e-071730318082680
Pubmed

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.

COL4A2 COL4A3 COL4A4

4.68e-07183039160753
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

COL4A2 COL4A3 COL4A4 COL4A6

6.46e-077930418757743
Pubmed

COL4A3/COL4A4 mutations and features in individuals with autosomal recessive Alport syndrome.

COL4A3 COL4A4

7.19e-07230224052634
Pubmed

Clinico-pathological correlations in 127 patients in 11 large pedigrees, segregating one of three heterozygous mutations in the COL4A3/ COL4A4 genes associated with familial haematuria and significant late progression to proteinuria and chronic kidney disease from focal segmental glomerulosclerosis.

COL4A3 COL4A4

7.19e-07230219357112
Pubmed

Type-IV collagen related diseases.

COL4A3 COL4A4

7.19e-07230212768082
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

7.19e-07230230542613
Pubmed

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.

COL4A3 COL4A4

7.19e-07230225229338
Pubmed

COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy.

COL4A3 COL4A4

7.19e-07230217942953
Pubmed

Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconus.

COL4A3 COL4A4

7.19e-07230220029656
Pubmed

Mutation analysis of COL4A3 and COL4A4 genes in a Chinese autosomal-dominant Alport syndrome family.

COL4A3 COL4A4

7.19e-07230228674241
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

7.19e-07230215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

7.19e-07230211673493
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

7.19e-07230211673462
Pubmed

Persistent familial hematuria in children and the locus for thin basement membrane nephropathy.

COL4A3 COL4A4

7.19e-07230216235097
Pubmed

Two genes, COL4A3 and COL4A4 coding for the human alpha3(IV) and alpha4(IV) collagen chains are arranged head-to-head on chromosome 2q36.

COL4A3 COL4A4

7.19e-0723029537506
Pubmed

Whole exome sequencing reveals novel COL4A3 and COL4A4 mutations and resolves diagnosis in Chinese families with kidney disease.

COL4A3 COL4A4

7.19e-07230225381091
Pubmed

Collagen type IV (alpha3-alpha4) nephropathy: from isolated haematuria to renal failure.

COL4A3 COL4A4

7.19e-07230215280517
Pubmed

Identification of mutations in the alpha 3(IV) and alpha 4(IV) collagen genes in autosomal recessive Alport syndrome.

COL4A3 COL4A4

7.19e-0723027987396
Pubmed

Heterozygous COL4A3/COL4A4 mutations: the hidden part of the iceberg?

COL4A3 COL4A4

7.19e-07230235090027
Pubmed

The genetics of thin basement membrane nephropathy.

COL4A3 COL4A4

7.19e-07230215880327
Pubmed

The COL4A3 and COL4A4 Digenic Mutations in cis Result in Benign Familial Hematuria in a Large Chinese Family.

COL4A3 COL4A4

7.19e-07230229742505
Pubmed

NPHS2 gene polymorphism aggravates renal damage caused by focal segmental glomerulosclerosis with COL4A3 mutation.

COL4A3 NPHS2

7.19e-07230233305316
Pubmed

Is there a dominant-negative effect in individuals with heterozygous disease-causing variants in COL4A3/COL4A4?

COL4A3 COL4A4

7.19e-07230238214412
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

7.19e-07230217259277
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

7.19e-07230225370123
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

7.19e-07230215033925
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

7.19e-07230214722100
Pubmed

Nine novel COL4A3 and COL4A4 mutations and polymorphisms identified in inherited membrane diseases.

COL4A3 COL4A4

7.19e-07230217216251
Pubmed

Co-Inheritance of Functional Podocin Variants with Heterozygous Collagen IV Mutations Predisposes to Renal Failure.

COL4A3 NPHS2

7.19e-07230226138234
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

7.19e-07230226009179
Pubmed

Heterozygous Urinary Abnormality-Causing Variants of COL4A3 and COL4A4 Affect Severity of Autosomal Recessive Alport Syndrome.

COL4A3 COL4A4

7.19e-07230235369551
Pubmed

Presumed COL4A3/COL4A4 Missense/Synonymous Variants Induce Aberrant Splicing.

COL4A3 COL4A4

7.19e-07230235386907
Pubmed

COL4A3/COL4A4 mutations: from familial hematuria to autosomal-dominant or recessive Alport syndrome.

COL4A3 COL4A4

7.19e-07230212028435
Pubmed

Polymorphism analysis of COL4A3 and COL4A4 genes in Greek patients with keratoconus.

COL4A3 COL4A4

7.19e-07230225083577
Pubmed

Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.

COL4A3 COL4A4

7.19e-07230220847057
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

7.19e-07230218618700
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

7.19e-07230232899693
Pubmed

Collagen type IV-related nephropathies in Portugal: pathogenic COL4A3 and COL4A4 mutations and clinical characterization of 25 families.

COL4A3 COL4A4

7.19e-07230225307543
Pubmed

COL4A3/COL4A4 mutations link familial hematuria and focal segmental glomerulosclerosis. glomerular epithelium destruction via basement membrane thinning?

COL4A3 COL4A4

7.19e-07230218661361
Pubmed

Genetic, Clinical, and Pathologic Backgrounds of Patients with Autosomal Dominant Alport Syndrome.

COL4A3 COL4A4

7.19e-07230227281700
Pubmed

Phenotype/Genotype Relationship in Left Ventricular Noncompaction: Ion Channel Gene Mutations Are Associated With Preserved Left Ventricular Systolic Function and Biventricular Noncompaction: Phenotype/Genotype of Noncompaction.

HCN4 RYR2

7.19e-07230234088380
InteractionHABP2 interactions

COL4A2 COL4A3 COL4A4 COL4A6

1.20e-0818304int:HABP2
InteractionOSM interactions

COL4A2 COL4A3 COL4A4 COL4A6

1.90e-0820304int:OSM
InteractionMMP9 interactions

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6

4.66e-0867305int:MMP9
InteractionTGFBI interactions

COL2A1 COL4A2 COL4A3 COL4A4

4.94e-0825304int:TGFBI
InteractionCD93 interactions

COL4A2 COL4A3 COL4A4 COL4A6

5.70e-0745304int:CD93
InteractionLAIR2 interactions

COL2A1 COL4A2 COL4A4 COL4A6

8.07e-0749304int:LAIR2
InteractionSERPINE2 interactions

COL4A2 COL4A3 COL4A4 COL4A6

1.39e-0656304int:SERPINE2
InteractionFN1 interactions

COL2A1 COL4A2 COL4A3 COL4A4 BROX COL4A6 DDAH2 ILF2 XRCC5

2.55e-06848309int:FN1
InteractionFBLN2 interactions

COL4A2 COL4A3 COL4A4 COL4A6

2.70e-0666304int:FBLN2
InteractionANTXR2 interactions

COL4A2 COL4A3 COL4A4

1.06e-0529303int:ANTXR2
InteractionMATN2 interactions

COL4A2 COL4A3 COL4A4 COL4A6

2.29e-05113304int:MATN2
InteractionSOX2 interactions

YOD1 DDAH2 DLG5 KMT2D ILF2 XRCC5 BCOR AHDC1 SUPV3L1 RYR1

2.41e-0514223010int:SOX2
InteractionCOL8A2 interactions

COL2A1 COL4A2 COL4A6

3.29e-0542303int:COL8A2
InteractionDCN interactions

COL4A3 COL4A4 COL4A6

3.53e-0543303int:DCN
InteractionC1QTNF1 interactions

COL2A1 COL4A2 COL4A6

4.62e-0547303int:C1QTNF1
InteractionSAA1 interactions

COL4A2 COL4A3 COL4A4

7.01e-0554303int:SAA1
InteractionP4HA1 interactions

COL2A1 COL4A2 PON2 COL4A6 FOXL2

7.19e-05298305int:P4HA1
InteractionCOL9A1 interactions

COL2A1 COL4A2

1.65e-0413302int:COL9A1
InteractionKCNA3 interactions

COL4A3 COL4A4 DLG5 ILF2 XRCC5 COL27A1 RYR1

2.34e-04871307int:KCNA3
InteractionAKAP6 interactions

RYR1 RYR2

2.87e-0417302int:AKAP6
InteractionFKBP9 interactions

COL2A1 COL4A2 COL4A6

2.90e-0487303int:FKBP9
InteractionMMP2 interactions

COL2A1 COL4A2 COL4A6

2.90e-0487303int:MMP2
InteractionERG interactions

KMT2D ILF2 XRCC5 BCOR

3.19e-04223304int:ERG
CytobandXq22

COL4A6 GUCY2F

9.46e-0522302Xq22
CytobandEnsembl 112 genes in cytogenetic band chr2q36

COL4A3 COL4A4

1.42e-0385302chr2q36
GeneFamilyCollagens

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

1.02e-1146216490
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

3.85e-063212287
CoexpressionNABA_COLLAGENS

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

7.81e-1243306MM17060
CoexpressionNABA_COLLAGENS

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 COL27A1

9.04e-1244306M3005
CoexpressionNABA_CORE_MATRISOME

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

1.89e-08270307MM17057
CoexpressionNABA_CORE_MATRISOME

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

2.15e-08275307M5884
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A2 COL4A3 COL4A4 COL4A6

1.24e-0740304M5887
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A2 COL4A3 COL4A4

2.36e-0623303M48001
CoexpressionLI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN

COL2A1 DLG5 ILF2 XRCC5

3.57e-05164304M13108
CoexpressionPEREZ_TP53_TARGETS

COL2A1 COL4A4 EMILIN3 DLG5 FOXL2 BCOR AHDC1 COL27A1

4.50e-051201308M4391
CoexpressionGSE34156_UNTREATED_VS_24H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP

COL4A6 DDAH2 DLG5 KMT2D

7.14e-05196304M8683
CoexpressionGSE27786_BCELL_VS_MONO_MAC_DN

PRR32 COL4A6 NPHS2 CEMIP2

7.72e-05200304M4818
CoexpressionGSE557_WT_VS_CIITA_KO_DC_DN

DLG5 KMT2D COL27A1 RYR1

7.72e-05200304M6008
CoexpressionGSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP

YOD1 NPHS2 BCOR CEMIP2

7.72e-05200304M7898
CoexpressionHALLMARK_KRAS_SIGNALING_DN

COL2A1 KMT2D RYR1 RYR2

7.72e-05200304M5956
CoexpressionNABA_MATRISOME

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

1.14e-041008307MM17056
CoexpressionBAELDE_DIABETIC_NEPHROPATHY_DN

COL4A3 COL4A4 COL4A6 DLG5 XRCC5

1.27e-04437305M4665
CoexpressionNABA_MATRISOME

COL2A1 COL4A2 COL4A3 COL4A4 COL4A6 EMILIN3 COL27A1

1.27e-041026307M5889
CoexpressionKANG_AR_TARGETS_UP

COL2A1 COL4A2

1.70e-0417302M2223
CoexpressionKANG_AR_TARGETS_UP

COL2A1 COL4A2

1.70e-0417302MM1297
CoexpressionRIZKI_TUMOR_INVASIVENESS_3D_DN

COL2A1 COL4A4 HCN4 CEMIP2

2.18e-04262304M11472
CoexpressionSMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP

COL2A1 RYR1

2.88e-0422302M5840
CoexpressionCUI_TCF21_TARGETS_2_DN

COL4A3 PON2 COL4A4 YOD1 NPHS2 CEMIP2

3.57e-04854306M1533
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPROGM

COL2A1 PON2 COL27A1 CEMIP2

3.98e-04307304M39058
CoexpressionCUI_TCF21_TARGETS_2_DN

COL4A3 PON2 COL4A4 YOD1 NPHS2 CEMIP2

4.40e-04888306MM1018
CoexpressionCTIP_DN.V1_DN

DDAH2 NPHS2 HCN4

4.79e-04134303M2751
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2C

COL2A1 PON2 FOXL2 COL27A1

4.93e-04325304M39053
CoexpressionHOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN

COL2A1 RYR1

5.40e-0430302M743
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL2A1 COL4A2 COL4A3 COL4A4

4.13e-0616230457d627259d27f39885bf416d74bcb6656db6e27b
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

COL2A1 COL4A2 COL4A6 COL27A1

5.47e-06174304fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 COL4A6

6.83e-06184304ca940a4f4970285ed284d5517d142abab0682044
ToppCellwk_20-22-Epithelial-Distal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL2A1 COL4A3 PON2 COL4A4

8.76e-06196304cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 COL4A4 EMILIN3

9.30e-061993049c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL4A3 PON2 COL4A4

9.30e-061993042e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 COL4A4 EMILIN3

9.30e-061993043835452e4848d7f7dd8651c17b746b271ef39688
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL4A6

7.31e-051213035035e071033cb76a7fc0128716755b14821e8f05
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL4A6

7.31e-05121303c96115bd33455296378a257583b49442d00b39ca
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A4 COL4A6 GUCY2F

1.27e-04146303669001b772b6d6109a09727619ed5829122b48db
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

1.52e-04155303010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellsevere_COVID-19-cDC|World / disease group, cell group and cell class (v2)

PON2 COL27A1 RYR1

1.55e-041563030a7e18ed8e13261c405eb6b9a183e99d8e1aac37
ToppCellsevere_COVID-19-cDC|severe_COVID-19 / disease group, cell group and cell class (v2)

PON2 COL27A1 RYR1

1.58e-04157303ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 COL4A6 RYR2

1.61e-041583038d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A2 COL4A3 COL4A4

1.67e-0416030358ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 PON2 COL4A4

1.70e-041613031e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A3 COL4A4 DDAH2

1.70e-0416130363f0b97c741b610c450f65fa5764d712bfe09ce8
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

COL4A2 COL4A4 CEMIP2

1.70e-041613031973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

1.73e-04162303ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

COL4A3 COL4A4 COL4A6

1.83e-04165303b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL2A1 AHDC1 COL27A1

1.86e-0416630337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellCV-Mild-3|Mild / Virus stimulation, Condition and Cluster

PON2 YOD1 AHDC1

1.86e-041663035599f90fc0e15a3670b03187085eba91228390a2
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL2A1 AHDC1 COL27A1

1.86e-0416630381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

COL4A2 COL4A3 COL4A4

1.96e-041693036373562ab3b1765060212a6a53d6543e7e942e80
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A6 DLG5 RYR1

2.00e-041703032d880223d01bde4bf777bd6f50b7d2768489075f
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

COL4A2 COL4A3 COL4A4

2.00e-04170303e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A6 DLG5 RYR1

2.00e-041703030cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPE RYR1 CEMIP2

2.03e-04171303355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 COL4A3 RYR2

2.03e-04171303a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellAT1-AT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A4 DLG5

2.03e-041713030b9912f07393aca889db72b40da08e0bc9bc1e8c
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

COL4A2 COL4A6 RYR2

2.07e-04172303c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 EMILIN3 RYR2

2.07e-04172303858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

PON2 COL4A4 YOD1

2.10e-0417330362e0c18cfed9645e34a9d7029c94a8554f773714
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.10e-041733033afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCellmild_COVID-19_(asymptomatic)-cDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

PON2 DDAH2 RYR1

2.10e-0417330371dc0051c87b84e3cf13cde8858166f2a474b5dc
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPE HCN4 CEMIP2

2.14e-041743039d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPE HCN4 CEMIP2

2.14e-0417430353cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

COL4A2 COL4A3 COL4A4

2.14e-04174303548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A4 NPHS2

2.17e-04175303a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.17e-04175303bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellIIF-Lymphocyte-B-B_intermediate|IIF / Disease, Lineage and Cell Type

COL4A3 COL4A4 DDAH2

2.17e-04175303327f8ee3669c3fc5ba50abc3b4f3e068637fd8d8
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.17e-041753039a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.21e-041763034a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.21e-04176303458720776b0151cd55acc352d509599cb62f0ca8
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.25e-041773033128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL2A1 EMILIN3 COL27A1

2.29e-04178303a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 COL4A3 COL4A4

2.29e-04178303f332c7a96844abecf05ca057480fbea9296688a2
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.32e-041793031603117b52623663458a977c94bf7f9f6c1114b8
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4

2.32e-041793034f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 COL4A6 CEBPE

2.32e-04179303a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 COL4A4 COL4A6

2.36e-0418030339ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellmild_COVID-19_(asymptomatic)-cDC|World / disease group, cell group and cell class (v2)

PON2 DDAH2 RYR1

2.36e-0418030368d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCellAT1_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.36e-04180303e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A2 COL4A3 COL4A4

2.40e-041813032b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 COL4A3 COL4A4

2.40e-041813039842537f9a607d8557c43790008d175edab1f32c
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.40e-04181303ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

COL4A2 DDAH2 CEMIP2

2.40e-041813039cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6

2.44e-04182303a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 PON2 COL4A4

2.44e-04182303cc79e0cc21e2fdc4ef77f052818d27b9f707aec1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A2 COL27A1 RYR2

2.44e-04182303ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL2A1 EMILIN3 COL27A1

2.44e-0418230303a5a02acd48f0eb210485348bfe0cd21f486215
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 NPHS2

2.48e-041833033c516fe5083f02bad1f464ed284010b4131a833c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 PON2 COL4A4

2.48e-04183303274483009b309289e4cb84beedf6806430db6ff6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 NPHS2

2.48e-041833039c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.48e-041833036821dca076318115d360ff426eb1218cfe104063
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 GUCY2F RYR2

2.52e-04184303ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 GUCY2F RYR2

2.52e-041843032cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 PON2 COL4A4

2.52e-04184303cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 GUCY2F RYR2

2.52e-041843032b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 COL4A3 COL4A4

2.52e-0418430357c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6

2.52e-041843037cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4

2.52e-04184303561592edc3083fad41b91811151b442207c65dd9
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 COL4A3 COL4A4

2.52e-04184303ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 NPHS2

2.52e-041843037294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 COL4A3 COL4A4

2.52e-04184303d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellIIF-Lymphocyte-B-B_memory|IIF / Disease, Lineage and Cell Type

COL4A3 COL4A4 DDAH2

2.56e-04185303c0eeab45c4ddefe107690a4ba8868fed2962c730
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DDAH2 CEMIP2

2.56e-04185303742350093d90f96735dc73e3360cdd749bae63fd
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4

2.56e-041853031c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 PON2 COL4A4

2.56e-041853036da9a06e1514d5d5f47359a14637f02539846096
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL2A1 EMILIN3 COL27A1

2.56e-041853038ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL4A6 EMILIN3 RYR2

2.56e-041853037dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL2A1 KMT2D COL27A1

2.56e-04185303636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 PON2 COL4A4

2.56e-041853030c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6

2.56e-041853033937e026add96a396122139daf8011cfbc60e75c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 PON2 COL4A4

2.56e-041853034a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 NPHS2

2.56e-041853039197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL2A1 EMILIN3 COL27A1

2.56e-04185303b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 NPHS2

2.56e-04185303ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL4A3 COL4A4

2.60e-0418630390d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL4A3 COL4A4

2.60e-041863032cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

COL4A2 COL4A3 COL4A4

2.60e-04186303df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellIPF-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL4A2 COL4A3 COL4A4

2.60e-04186303d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 COL4A3 COL4A4

2.60e-0418630377592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6

2.64e-0418730358d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4

2.64e-04187303d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A2 COL4A3 COL4A4

2.64e-041873034ea486991f66c29728d127171a07b81404ec0b78
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A4 COL4A6

2.64e-04187303201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 NPHS2

2.64e-0418730324c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4

2.64e-0418730377f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4

2.64e-04187303f1dda349335e08dbfc8395d373924037f5ad2fd6
DrugGK-101

COL2A1 COL4A3 COL4A6 COL27A1

1.40e-0736304CID000161853
DrugMadecassol

COL2A1 COL4A3 COL4A6 COL27A1

3.84e-0746304CID000108062
Drugd-indobufen

COL2A1 COL4A3 COL4A6 COL27A1

5.41e-0750304CID000044562
DrugSelara

COL2A1 COL4A3 COL4A6 HCN4 COL27A1

5.88e-07125305CID000150310
Drugridogrel

COL2A1 COL4A3 COL4A6 COL27A1

6.34e-0752304CID005362391
DrugNSC49633

COL2A1 COL4A3 COL4A6 COL27A1

6.86e-0753304CID000023340
DrugAC1LAKND

COL2A1 COL4A3 COL4A6 COL27A1

1.30e-0662304CID000470146
DrugL-lysyl-L-lysyl-L-lysine

COL2A1 COL4A3 COL4A6 DDAH2 COL27A1

2.12e-06162305CID000072363
DrugBAPN

COL2A1 COL4A3 COL4A6 COL27A1

2.24e-0671304CID000001647
Drugmalotilate

COL2A1 COL4A3 COL4A6 COL27A1

2.24e-0671304CID000004006
DrugAC1NMZ1B

COL2A1 COL4A3 COL4A6 COL27A1

2.79e-0675304CID005034185
Drugstrontium ranelate

COL2A1 COL4A3 COL4A6 COL27A1

3.10e-0677304CID006918182
Drughalofuginone lactate

COL2A1 COL4A3 COL4A6 COL27A1

4.60e-0685304CID000062891
Drug2-hydroxyheptanoic acid

RYR1 RYR2

5.03e-063302CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR2

5.03e-063302CID005748312
Drug8N3-cADPR

RYR1 RYR2

5.03e-063302CID000127713
Drug2-hydroxycarbazole

RYR1 RYR2

5.03e-063302CID000093551
Drugaminodantrolene

RYR1 RYR2

5.03e-063302CID009570289
Drugcis-diammineplatinum(II

RYR1 RYR2

5.03e-063302CID000159790
Drug4-hydroxyproline

COL2A1 COL4A3 COL4A6 COL27A1

6.04e-0691304CID000000825
DrugAC1NUZ8M

COL2A1 DDAH2 GUCY2F RYR1

6.31e-0692304CID000073211
Drug2,4-xylidinothiazoline

COL2A1 RYR1 RYR2

8.18e-0630303CID000099296
Drugticlopidine

COL2A1 COL4A3 COL4A6 COL27A1

9.89e-06103304CID000005472
DrugSC 38249

RYR1 RYR2

1.01e-054302CID000134834
DrugAC1L1U7A

RYR1 RYR2

1.01e-054302CID000035682
DrugPCB74

RYR1 RYR2

1.01e-054302CID000036218
Drug148504-47-6

RYR1 RYR2

1.01e-054302CID006444275
Drughydroxylysine

COL2A1 COL4A3 COL4A6 COL27A1

1.24e-05109304CID000001029
DrugAC1L1C2F

COL2A1 COL4A3 COL4A6 COL27A1

1.28e-05110304CID000001711
DrugPPACK

COL2A1 COL4A3 COL4A6 COL27A1

1.43e-05113304CID003036757
DrugAC1L9732

COL2A1 COL4A3 COL4A6 COL27A1

1.48e-05114304CID000439300
DrugTranilast sodium

COL2A1 COL4A3 COL4A6 COL27A1

1.53e-05115304CID000005527
DrugAC1NBU2S

DDAH2 GUCY2F RYR1 RYR2

1.64e-05117304CID004473765
Drugfensulfothion

PON2 FOXL2

1.67e-055302CID000008292
DrugA 68930

RYR1 RYR2

1.67e-055302ctd:C065380
Drugcyclophorine

COL4A3 COL4A6 NPHS2 ILF2 RYR1 RYR2

1.68e-05426306CID000002909
DrugAC1O528X

RYR1 RYR2

2.51e-056302CID006475857
DrugNSC114784

RYR1 RYR2

2.51e-056302CID000419425
Drugvinyl phosphate

PON2 NPHS2

2.51e-056302CID000135020
DrugMBED

RYR1 RYR2

2.51e-056302CID000129958
Drugchloro-m-cresol

RYR1 RYR2

2.51e-056302CID000012008
DrugDMSe

COL2A1 COL4A3 COL4A6 COL27A1

2.63e-05132304CID000020796
Drug4,4'-dithiodipyridine

NEIL2 RYR1 RYR2

2.82e-0545303CID000075846
Drugpirfenidone

COL2A1 COL4A3 COL4A6 COL27A1

3.13e-05138304CID000040632
DrugDL-penicillamine

COL2A1 COL4A3 COL4A6 COL27A1

3.22e-05139304CID000004727
DrugPCR 4099

COL2A1 COL4A3 COL4A6 COL27A1

3.22e-05139304CID000002806
DrugAzumoleno

RYR1 RYR2

3.51e-057302CID000056259
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR2

3.51e-057302CID009547999
DrugBr2BAPTA

RYR1 RYR2

3.51e-057302CID003081001
DrugAC1L9KQO

XRCC5 RYR1 RYR2

3.65e-0549303CID000447335
Drugcandesartan cilexetil

COL2A1 COL4A3 COL4A6 COL27A1

3.80e-05145304CID000002540
Drugkhellin

COL2A1 COL4A3 COL4A6 COL27A1

7.23e-05171304CID000003828
DrugPCB 95

RYR1 RYR2

7.50e-0510302CID000038012
Druglercanidipine

HCN4 RYR1 RYR2

7.77e-0563303CID000065866
DrugAC1L1DD6

COL2A1 COL4A3 COL4A6 COL27A1

8.63e-05179304CID000002299
DrugR 478

RYR1 RYR2

9.16e-0511302CID000084223
Drug2,3,6,2',3',6'-hexachlorobiphenyl

RYR1 RYR2

9.16e-0511302ctd:C010498
Drug8-amino-cADPR

RYR1 RYR2

9.16e-0511302CID003081323
DrugPCB 66

RYR1 RYR2

9.16e-0511302CID000036185
Drugtectoridin

RYR1 RYR2

9.16e-0511302CID005281810
Drug12(S)-hydroxyeicosatetraenoic acid

COL2A1 COL4A3 COL4A6 COL27A1

1.06e-04189304CID000001413
Drugfoscarnet

COL2A1 COL4A3 COL4A6 COL27A1

1.09e-04190304CID000003414
DrugRyanodine

RYR1 RYR2

1.10e-0412302ctd:D012433
DrugSulfapyridine [144-83-2]; Up 200; 16uM; HL60; HT_HG-U133A

COL4A3 COL4A6 AHDC1 RYR2

1.20e-041953042538_UP
DrugGabazine [105538-73-6]; Up 200; 10.8uM; PC3; HT_HG-U133A

COL2A1 COL4A4 COL4A6 CEMIP2

1.27e-041983044236_UP
Drugpyrraline

COL4A3 RYR2

1.74e-0415302CID000122228
DrugFPL 64176

RYR1 RYR2

1.74e-0415302CID000003423
DrugGvapspat amide

RYR1 RYR2

1.74e-0415302CID000125015
DrugLMWH

COL2A1 COL4A3 COL4A6 COL27A1 RYR1 RYR2

1.95e-04663306CID000000772
DrugNOC 18

COL4A2 COL4A3

1.99e-0416302ctd:C093285
Drugkazinol B

RYR1 RYR2

2.25e-0417302CID000480869
DrugAC1Q6PCP

COL2A1 COL4A3 COL4A6 COL27A1

2.26e-04230304CID000005267
Drugmethylcoumarin

RYR1 RYR2

2.53e-0418302CID000007092
Drugisotetrandrine

COL2A1 RYR1 RYR2

2.80e-0497303CID000005422
DrugAC1L380G

RYR1 RYR2

2.83e-0419302CID000084698
DrugAC1MW7VF

RYR1 RYR2

2.83e-0419302CID000414699
DrugSK&F 82958

RYR1 RYR2

2.83e-0419302ctd:C071262
Drugprostacyclin sodium salt

COL2A1 COL4A3 COL4A6 COL27A1

3.11e-04250304CID000000159
DrugBaclofen

RYR1 RYR2

3.14e-0420302ctd:D001418
Drug351A

COL2A1 COL27A1

3.14e-0420302CID000122144
Drughygronium

PON2 XRCC5

3.14e-0420302CID000071512
Drug2,2',3,5',6-pentachlorobiphenyl

RYR1 RYR2

3.14e-0420302ctd:C032904
Drugindo-1/AM

RYR1 RYR2

3.47e-0421302CID000123918
Drugtectorigenin

RYR1 RYR2

3.47e-0421302CID005281811
Drugloperamide

HCN4 RYR1 RYR2

3.53e-04105303CID000003954
Drughyaluronan

COL2A1 COL4A3 COL4A6 COL27A1

3.76e-04263304CID000024759
DrugAC1L1KON

COL2A1 ILF2 XRCC5

4.61e-04115303CID000005589
DrugT0702

RYR1 RYR2

4.94e-0425302CID000005908
Drugalamos

PON2 FOXL2

4.94e-0425302CID000079914
Drugsilibinin

COL2A1 COL4A3 COL4A6 COL27A1

5.10e-04285304CID000005213
DrugLS-63783

COL2A1 COL4A3 PON2 COL4A6 GUCY2F COL27A1

5.47e-04804306CID000000231
DrugS-nitrosoacetylcysteine

GUCY2F RYR1

6.67e-0429302CID000122058
Drugexcavatolide B

COL4A3 RYR1

6.67e-0429302ctd:C574336
DrugBicuculline

RYR1 RYR2

6.67e-0429302ctd:D001640
Drug8-bromoguanosine 3',5'-cyclic monophosphate

HCN4 GUCY2F RYR1 RYR2

6.82e-04308304CID000001915
DrugLOPAC

RYR1 RYR2

7.14e-0430302CID000062696
DrugKT 5823

COL4A2 COL4A3

7.14e-0430302ctd:C073601
Drug(2s,5s)-5-Carboxymethylproline

COL2A1 COL4A3 COL4A6 COL27A1

7.33e-04314304CID000447989
DrugM-HN

RYR1 RYR2

7.62e-0431302CID000015450
DrugM3/M4

RYR1 RYR2

8.12e-0432302CID000486507
DiseaseHematuria, Benign Familial

COL4A3 COL4A4 NPHS2

3.06e-094283C0241908
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A4 NPHS2

7.64e-095283C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A4 NPHS2

7.64e-095283C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A4 NPHS2

7.64e-095283C1567744
Diseasehypertensive nephropathy

COL4A3 COL4A4 NPHS2

1.53e-086283C0848548
Diseasecollagen disease (implicated_via_orthology)

COL4A3 COL4A4 COL4A6

1.67e-0712283DOID:854 (implicated_via_orthology)
DiseaseALPORT SYNDROME 2, AUTOSOMAL RECESSIVE

COL4A3 COL4A4

8.68e-072282C4746745
Diseasebenign familial hematuria (is_implicated_in)

COL4A3 COL4A4

8.68e-072282DOID:0111365 (is_implicated_in)
Diseaseautosomal recessive Alport syndrome (is_implicated_in)

COL4A3 COL4A4

8.68e-072282DOID:0110033 (is_implicated_in)
DiseaseAlport syndrome, recessive type

COL4A3 COL4A4

8.68e-072282C2931254
DiseaseAlport syndrome, dominant type

COL4A3 COL4A4

8.68e-072282C2931253
DiseaseThin basement membrane disease

COL4A3 COL4A4

8.68e-072282C0403440
DiseaseBenign familial hematuria

COL4A3 COL4A4

8.68e-072282cv:C0241908
DiseaseRenal glomerular disease

COL4A3 COL4A4 NPHS2

1.34e-0623283C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A4 NPHS2

1.34e-0623283C4521256
DiseaseAlport syndrome

COL4A3 COL4A4

2.60e-063282cv:C1567741
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

2.60e-063282DOID:8545 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

2.60e-063282DOID:3529 (implicated_via_orthology)
Diseaseautosomal recessive Alport syndrome (implicated_via_orthology)

COL4A3 COL4A4

2.60e-063282DOID:0110033 (implicated_via_orthology)
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A4

2.60e-063282cv:CN076135
DiseaseAlport Syndrome

COL4A3 COL4A4

5.20e-064282C1567741
Diseasemyopathy (implicated_via_orthology)

COL4A3 COL4A4 COL4A6

1.29e-0548283DOID:423 (implicated_via_orthology)
Diseasemacula measurement

COL2A1 COL4A3 COL4A4 DLG5

2.96e-05189284EFO_0008375
DiseaseNephrotic Syndrome

COL4A2 NPHS2

3.00e-0427282C0027726
DiseaseHereditary hearing loss and deafness

COL2A1 COL4A3 COL4A4

3.55e-04146283cv:C0236038
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

COL4A3 NPHS2

3.72e-0430282C1868672
Diseasediastolic blood pressure, systolic blood pressure

COL4A2 PON2 EMILIN3 HCN4 RYR2

3.79e-04670285EFO_0006335, EFO_0006336
Diseaseretinal detachment, retinal break

COL2A1 DLG5

5.07e-0435282EFO_0005773, EFO_0010698
Diseaseend stage renal disease (is_implicated_in)

COL4A3 COL4A4

6.96e-0441282DOID:783 (is_implicated_in)
DiseaseAcute Promyelocytic Leukemia

CEBPE BCOR

8.76e-0446282C0023487

Protein segments in the cluster

PeptideGeneStartEntry
SFPFHGSRPAGLPGL

AGBL5

666

Q8NDL9
GAPGFPGISGHPGKK

COL4A6

831

Q14031
LIGPKGFPGFPGLHG

COL4A6

1161

Q14031
ARGLKGPGTPAFPHY

CEBPE

66

Q15744
IVFRKGPPGDHGLPG

COL4A3

441

Q01955
DPAFGHLGPPGKRGL

COL4A4

761

P53420
GQHGLPGFPGLKGVP

COL4A2

521

P08572
PQAHPGLGGGPKSGF

AHDC1

1571

Q5TGY3
LFPGHLAPKPGLPYG

BCOR

691

Q6W2J9
GFPGTPGLPGVKGHR

COL2A1

276

P02458
PGLPGVKGHRGYPGL

COL2A1

281

P02458
KGRHFGVHPAPGFPG

YOD1

6

Q5VVQ6
PSPRLVLHFGGGGFL

NEIL2

161

Q969S2
PPAHFQPGKGLFGAG

FOXL2

156

P58012
PGGSSSFLHKPFPGG

DLG5

861

Q8TDM6
HLLPGRAKGPGLFFF

NPHS2

141

Q9NP85
PGARGGLGLPEHFLP

HCN4

946

Q9Y3Q4
FPGLHSFAPDKPGGI

PON2

71

Q15165
LRFGGTPIHFPGGRP

GUCY2F

431

P51841
RGGPGGGFRPFVPHI

ILF2

16

Q12905
GPHVSLNVFFGKPGP

CEMIP2

921

Q9UHN6
GRKGHKGYPGPAGHP

COL27A1

706

Q8IZC6
AAPSPHGRKGPGLFG

EMILIN3

166

Q9NT22
GLPGVPPFLLHRGGG

DDAH2

226

O95865
LLGGRHGEFKFLPPP

RYR1

791

P21817
GRHGEFKFLPPPGYA

RYR2

806

Q92736
LVPGLPGGGSAKFPF

MRPS15

21

P82914
HVALPQGKGFFPPRG

PRR32

161

B1ATL7
SALRPHFGPFPGVLG

SUPV3L1

26

Q8IYB8
GPGPTVKPSGHLFFR

BROX

296

Q5VW32
GPFRLGGHGPSFPLK

XRCC5

181

P13010
GINSHFGPGPTLGKP

KMT2D

2561

O14686