Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-L-arabinofuranosidase activity	OTOGL OTOG	1.67e-05	2	82	2	GO:0046556
GeneOntologyMolecularFunction	epidermal growth factor binding	NRDC SHC1	9.94e-05	4	82	2	GO:0048408
GeneOntologyBiologicalProcess	arabinose metabolic process	OTOGL OTOG	1.49e-05	2	80	2	GO:0019566
GeneOntologyBiologicalProcess	vibrational conductance of sound to the inner ear	OTOGL OTOG	1.49e-05	2	80	2	GO:0055127
GeneOntologyBiologicalProcess	L-arabinose metabolic process	OTOGL OTOG	1.49e-05	2	80	2	GO:0046373
GeneOntologyBiologicalProcess	membrane protein ectodomain proteolysis	NRDC ERAP1 SNX33 NCSTN	5.32e-05	53	80	4	GO:0006509
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I	ERAP2 ERAP1 MICB	9.41e-05	23	80	3	GO:0019885
GeneOntologyBiologicalProcess	membrane protein proteolysis	NRDC ERAP1 SNX33 NCSTN	1.12e-04	64	80	4	GO:0033619
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen	ERAP2 ERAP1 MICB	1.22e-04	25	80	3	GO:0002483
Domain	VWC_out	CRIM1 MUC5AC OTOG	7.24e-05	19	81	3	SM00215
Domain	SAPAP	DLGAP1 DLGAP3	1.84e-04	5	81	2	IPR005026
Domain	GKAP	DLGAP1 DLGAP3	1.84e-04	5	81	2	PF03359
Domain	Hirudin/antistatin	CRIM1 MUC5AC	3.85e-04	7	81	2	IPR011061
Domain	ERAP1-like_C_dom	ERAP2 ERAP1	5.11e-04	8	81	2	IPR024571
Domain	ERAP1_C	ERAP2 ERAP1	5.11e-04	8	81	2	PF11838
Domain	VWF_dom	CRIM1 MUC5AC OTOG	7.99e-04	42	81	3	IPR001007
Domain	LamG	FAT3 TSPEAR LAMA2	9.16e-04	44	81	3	SM00282
Domain	DOCK_C	DOCK4 DOCK11	9.96e-04	11	81	2	IPR010703
Domain	DHR-1_domain	DOCK4 DOCK11	9.96e-04	11	81	2	IPR027007
Domain	DHR_2	DOCK4 DOCK11	9.96e-04	11	81	2	PS51651
Domain	DHR_1	DOCK4 DOCK11	9.96e-04	11	81	2	PS51650
Domain	DOCK-C2	DOCK4 DOCK11	9.96e-04	11	81	2	PF14429
Domain	DHR-2	DOCK4 DOCK11	9.96e-04	11	81	2	IPR027357
Domain	DHR-2	DOCK4 DOCK11	9.96e-04	11	81	2	PF06920
Domain	DOCK	DOCK4 DOCK11	9.96e-04	11	81	2	IPR026791
Domain	TIL	MUC5AC OTOG	1.19e-03	12	81	2	PF01826
Domain	Peptidase_M1	ERAP2 ERAP1	1.19e-03	12	81	2	IPR001930
Domain	C8	MUC5AC OTOG	1.19e-03	12	81	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC5AC OTOG	1.40e-03	13	81	2	IPR014853
Domain	Peptidase_M1	ERAP2 ERAP1	1.40e-03	13	81	2	PF01433
Domain	C8	MUC5AC OTOG	1.40e-03	13	81	2	SM00832
Domain	Peptidase_M1_N	ERAP2 ERAP1	1.40e-03	13	81	2	IPR014782
Domain	TIL_dom	MUC5AC OTOG	1.63e-03	14	81	2	IPR002919
Domain	Laminin_G	FAT3 TSPEAR LAMA2	2.04e-03	58	81	3	IPR001791
Domain	VWD	MUC5AC OTOG	2.14e-03	16	81	2	SM00216
Domain	VWF_type-D	MUC5AC OTOG	2.14e-03	16	81	2	IPR001846
Domain	VWFD	MUC5AC OTOG	2.14e-03	16	81	2	PS51233
Domain	VWD	MUC5AC OTOG	2.14e-03	16	81	2	PF00094
Domain	CT	MUC5AC OTOG	4.06e-03	22	81	2	SM00041
Domain	Cys_knot_C	MUC5AC OTOG	5.22e-03	25	81	2	IPR006207
Domain	CTCK_2	MUC5AC OTOG	5.22e-03	25	81	2	PS01225
Pathway	WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_AUTOPHAGY	ATG7 MTOR ULK1	4.66e-05	19	53	3	M39903
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PHLDB1 MTOR SHC1 IPP ZFYVE26 WDR90 ULK1 HERC2 ITGA5 BCL2L13 ST14 SBNO2 FANCA	2.78e-06	1105	85	13	35748872
Pubmed	Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.	ERAP2 ERAP1	5.90e-06	2	85	2	18393273
Pubmed	Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.	ERAP2 ERAP1	5.90e-06	2	85	2	19433412
Pubmed	The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing.	ERAP2 ERAP1	5.90e-06	2	85	2	22106953
Pubmed	Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.	ERAP2 ERAP1	5.90e-06	2	85	2	15908954
Pubmed	Synergy of endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1 and ERAP2) polymorphisms in atopic dermatitis: Effects on disease prevalence.	ERAP2 ERAP1	5.90e-06	2	85	2	33309189
Pubmed	Antigenic peptide trimming by ER aminopeptidases--insights from structural studies.	ERAP2 ERAP1	5.90e-06	2	85	2	23545452
Pubmed	Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.	ERAP2 ERAP1	5.90e-06	2	85	2	29108111
Pubmed	mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms.	MTOR ULK1	5.90e-06	2	85	2	38325289
Pubmed	siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy.	MTOR ULK1	5.90e-06	2	85	2	17595159
Pubmed	[Interleukin-37 induces apoptosis and autophagy of SMMC-7721 cells by inhibiting phosphorylation of mTOR].	IL37 MTOR	5.90e-06	2	85	2	28395710
Pubmed	The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset.	ERAP2 ERAP1	5.90e-06	2	85	2	29183862
Pubmed	An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes.	ERAP2 ERAP1	5.90e-06	2	85	2	29991817
Pubmed	Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome.	ERAP2 ERAP1	5.90e-06	2	85	2	28063628
Pubmed	The ERAP gene is associated with HCV chronic infection in a Chinese Han population.	ERAP2 ERAP1	5.90e-06	2	85	2	29037997
Pubmed	The HIV-1 gp41 ectodomain is cleaved by matriptase to produce a chemotactic peptide that acts through FPR2.	FPR2 ST14	5.90e-06	2	85	2	24617769
Pubmed	Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.	ERAP2 ERAP1	5.90e-06	2	85	2	32321463
Pubmed	Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis.	ERAP2 ERAP1	5.90e-06	2	85	2	30215709
Pubmed	The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues.	ERAP2 ERAP1	5.90e-06	2	85	2	12436110
Pubmed	An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides.	ERAP2 ERAP1	5.90e-06	2	85	2	12436109
Pubmed	ERAP1-ERAP2 haplotypes are associated with ankylosing spondylitis in Polish patients.	ERAP2 ERAP1	5.90e-06	2	85	2	30794838
Pubmed	Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene.	ERAP2 ERAP1	5.90e-06	2	85	2	11481040
Pubmed	The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities.	ERAP2 ERAP1	5.90e-06	2	85	2	36569828
Pubmed	IL-37 induces autophagy in hepatocellular carcinoma cells by inhibiting the PI3K/AKT/mTOR pathway.	IL37 MTOR	5.90e-06	2	85	2	28433890
Pubmed	Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection.	ERAP2 ERAP1	5.90e-06	2	85	2	20843824
Pubmed	The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism.	MTOR SHC1	5.90e-06	2	85	2	24550542
Pubmed	ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing.	ERAP2 ERAP1	5.90e-06	2	85	2	27514473
Pubmed	A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2.	ERAP2 ERAP1	5.90e-06	2	85	2	36834865
Pubmed	The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia.	ERAP2 ERAP1	5.90e-06	2	85	2	32210971
Pubmed	Serum cytokine receptors in ankylosing spondylitis: relationship to inflammatory markers and endoplasmic reticulum aminopeptidase polymorphisms.	ERAP2 ERAP1	5.90e-06	2	85	2	20595269
Pubmed	ERAP1-ERAP2 dimerization increases peptide-trimming efficiency.	ERAP2 ERAP1	5.90e-06	2	85	2	24928998
Pubmed	Similar phenotypes caused by mutations in OTOG and OTOGL.	OTOGL OTOG	5.90e-06	2	85	2	24378291
Pubmed	Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma.	ERAP2 ERAP1	5.90e-06	2	85	2	20419298
Pubmed	ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum.	ERAP2 ERAP1	5.90e-06	2	85	2	17088086
Pubmed	Phospholipase D-mediated autophagic regulation is a potential target for cancer therapy.	ATG7 ULK1	5.90e-06	2	85	2	24317201
Pubmed	Comparative expression profiling for human endoplasmic reticulum-resident aminopeptidases 1 and 2 in normal kidney versus distinct renal cell carcinoma subtypes.	ERAP2 ERAP1	5.90e-06	2	85	2	23696916
Pubmed	Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.	ERAP2 ERAP1	5.90e-06	2	85	2	33762660
Pubmed	Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.	ERAP2 ERAP1	5.90e-06	2	85	2	16585582
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CLIP4 DOCK4 ERAP1 BCORL1 SHC1 CSTF1 SNX33 NCSTN LENG9 OTOG	7.18e-06	689	85	10	36543142
Pubmed	Interaction between STK33 and autophagy promoted renal cell carcinoma metastasis by regulating mTOR/ULK1 signaling pathway.	MTOR ULK1	1.77e-05	3	85	2	37101009
Pubmed	Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases.	ERAP2 ERAP1	1.77e-05	3	85	2	25142031
Pubmed	ERAP1/ERAP2 and RUNX3 polymorphisms are not associated with ankylosing spondylitis susceptibility in Chinese Han.	ERAP2 ERAP1	1.77e-05	3	85	2	29480940
Pubmed	Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2.	MTOR ITGA5	1.77e-05	3	85	2	36438491
Pubmed	ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes.	ERAP2 ERAP1	1.77e-05	3	85	2	37686141
Pubmed	Regulation of the human leukocyte-derived arginine aminopeptidase/endoplasmic reticulum-aminopeptidase 2 gene by interferon-gamma.	ERAP2 ERAP1	1.77e-05	3	85	2	15691326
Pubmed	Withdrawal of essential amino acids increases autophagy by a pathway involving Ca2+/calmodulin-dependent kinase kinase-β (CaMKK-β).	MTOR ULK1	1.77e-05	3	85	2	23027865
Pubmed	The interplay between HLA-B27 and ERAP1/ERAP2 aminopeptidases: from anti-viral protection to spondyloarthritis.	ERAP2 ERAP1	1.77e-05	3	85	2	28759104
Pubmed	Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides.	ERAP2 ERAP1	1.77e-05	3	85	2	21314638
Pubmed	mTORC1 restricts hepatitis C virus RNA replication through ULK1-mediated suppression of miR-122 and facilitates post-replication events.	MTOR ULK1	1.77e-05	3	85	2	31821132
Pubmed	The oxytocinase subfamily of M1 aminopeptidases.	ERAP2 ERAP1	1.77e-05	3	85	2	16054015
Pubmed	Differential contribution of the MTOR and MNK pathways to the regulation of mRNA translation in meiotic and postmeiotic mouse male germ cells.	MTOR MKNK2	1.77e-05	3	85	2	20574055
Pubmed	Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.	ATG7 ULK1	1.77e-05	3	85	2	22452982
Pubmed	A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy.	ULK1 BCL2L13	1.77e-05	3	85	2	30625316
Pubmed	ERAP1 and ERAP2 Gene Variations Influence the Risk of Psoriatic Arthritis in Romanian Population.	ERAP2 ERAP1	1.77e-05	3	85	2	28083616
Pubmed	ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers.	ERAP2 ERAP1	1.77e-05	3	85	2	34727153
Pubmed	Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.	ATG7 MTOR	1.77e-05	3	85	2	25155956
Pubmed	Suppression of autophagy impedes glioblastoma development and induces senescence.	ATG7 ULK1	1.77e-05	3	85	2	27304681
Pubmed	AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis.	MTOR ULK1	1.77e-05	3	85	2	37731335
Pubmed	Induction of autophagy in Cx3cr1+ mononuclear cells limits IL-23/IL-22 axis-mediated intestinal fibrosis.	ATG7 MTOR	1.77e-05	3	85	2	30765845
Pubmed	Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases.	ERAP2 ERAP1	1.77e-05	3	85	2	24223975
Pubmed	Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways.	ATG7 MTOR	1.77e-05	3	85	2	25906314
Pubmed	Pharmacologic co-inhibition of Mnks and mTORC1 synergistically suppresses proliferation and perturbs cell cycle progression in blast crisis-chronic myeloid leukemia cells.	MTOR MKNK2	1.77e-05	3	85	2	25527453
Pubmed	Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.	ERAP2 ERAP1	1.77e-05	3	85	2	36716917
Pubmed	miR‑654‑5p inhibits autophagy by targeting ATG7 via mTOR signaling in intervertebral disc degeneration.	ATG7 MTOR	1.77e-05	3	85	2	33846806
Pubmed	ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.	MTOR ULK1	3.53e-05	4	85	2	19258318
Pubmed	A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.	ERAP2 ERAP1	3.53e-05	4	85	2	24957906
Pubmed	Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy.	MTOR ULK1	3.53e-05	4	85	2	25980607
Pubmed	ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.	ATG7 ULK1	3.53e-05	4	85	2	30979586
Pubmed	mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex.	MTOR ULK1	3.53e-05	4	85	2	19690328
Pubmed	TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly.	MTOR ULK1	3.53e-05	4	85	2	37635626
Pubmed	BNIP3 is degraded by ULK1-dependent autophagy via MTORC1 and AMPK.	MTOR ULK1	3.53e-05	4	85	2	23291726
Pubmed	Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.	MTOR MKNK2	3.53e-05	4	85	2	26147685
Pubmed	Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.	ATG7 ULK1	3.53e-05	4	85	2	24895007
Pubmed	Autophagy Genes for Wet Age-Related Macular Degeneration in a Finnish Case-Control Study.	MTOR ULK1	5.87e-05	5	85	2	33172148
Pubmed	CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells.	ATG7 USP28	5.87e-05	5	85	2	30635654
Pubmed	Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.	DLGAP1 DLGAP3	5.87e-05	5	85	2	15024750
Pubmed	Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.	ERAP1 MICB	5.87e-05	5	85	2	22286212
Pubmed	Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death.	ATG7 ULK1	5.87e-05	5	85	2	22493260
Pubmed	Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.	MTOR ULK1	5.87e-05	5	85	2	19211835
Pubmed	Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor.	MTOR SHC1	5.87e-05	5	85	2	21454706
Pubmed	NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells.	ERAP2 ERAP1	5.87e-05	5	85	2	20103633
Pubmed	Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells.	ATG7 ULK1	5.87e-05	5	85	2	21969579
Pubmed	Manganese is a physiologically relevant TORC1 activator in yeast and mammals.	MTOR ULK1	5.87e-05	5	85	2	35904415
Pubmed	PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development.	MTOR ULK1	5.87e-05	5	85	2	27545895
Pubmed	Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes.	ATG7 MTOR	5.87e-05	5	85	2	25339774
Pubmed	A role for BCL2L13 and autophagy in germline purifying selection of mtDNA.	ULK1 BCL2L13	5.87e-05	5	85	2	36608143
Pubmed	The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.	ATG7 ULK1	5.87e-05	5	85	2	27203176
Pubmed	Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.	MTOR ULK1	5.87e-05	5	85	2	26593251
Pubmed	Digitoxin Suppresses Human Cytomegalovirus Replication via Na+, K+/ATPase α1 Subunit-Dependent AMP-Activated Protein Kinase and Autophagy Activation.	MTOR ULK1	5.87e-05	5	85	2	29321306
Pubmed	Global Proximity Interactome of the Human Macroautophagy Pathway.	ATG7 CSTF1 ULK1	8.71e-05	35	85	3	34524948
Pubmed	Annexin A2 Regulates Autophagy in Pseudomonas aeruginosa Infection through the Akt1-mTOR-ULK1/2 Signaling Pathway.	MTOR ULK1	8.80e-05	6	85	2	26371245
Pubmed	ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.	MTOR ULK1	8.80e-05	6	85	2	19225151
Pubmed	Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes.	ATG7 ULK1	1.23e-04	7	85	2	23219390
Pubmed	Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.	ATG7 ULK1	1.23e-04	7	85	2	23525089
Pubmed	Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.	ATG7 MTOR	1.23e-04	7	85	2	24011591
Pubmed	Murine lipid phosphate phosphohydrolase-3 acts as a cell-associated integrin ligand.	SHC1 ITGA5	1.23e-04	7	85	2	16099422
Pubmed	Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.	ATG7 ULK1	1.23e-04	7	85	2	28389568
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT3	1.23e-04	7	85	2	16059920
Pubmed	AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.	MTOR ULK1	1.23e-04	7	85	2	21258367
Pubmed	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.	DLGAP1 DLGAP3	1.23e-04	7	85	2	9115257
Cytoband	1q44	OR2T27 OR2T7 OR2T1	1.15e-03	110	85	3	1q44
Cytoband	7p21.3	ETV1 GLCCI1	1.24e-03	28	85	2	7p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2T27 OR2T7 OR2T1	1.77e-03	128	85	3	chr1q44
Cytoband	5q15	ERAP2 ERAP1	2.52e-03	40	85	2	5q15
GeneFamily	Cadherin related	DCHS2 FAT3	1.38e-03	17	59	2	24
GeneFamily	Aminopeptidases\|CD molecules	ERAP2 ERAP1	1.38e-03	17	59	2	104
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTS12 DOCK4 DLGAP1 SDK2 CRIM1 FAT3 ETV1 SLC40A1	3.60e-09	193	85	8	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK4 UHMK1 IPP HERC2 SH2D5 DOP1A	8.20e-07	167	85	6	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTS12 DOCK4 DLGAP1 FAT3 LAMA2 SLC40A1	1.69e-06	189	85	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTS12 DOCK4 SDK2 FAT3 ETV1 SLC40A1	1.85e-06	192	85	6	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS12 DOCK4 DLGAP1 SDK2 FAT3 LAMA2	1.90e-06	193	85	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTS12 DOCK4 DLGAP1 SDK2 FAT3 LAMA2	1.96e-06	194	85	6	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTS12 DLGAP1 GUCY1A2 FAT3 ETV1 LAMA2	1.96e-06	194	85	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 GUCY1A2 FAT3 ETV1 LAMA2 SLC40A1	2.14e-06	197	85	6	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTS12 DOCK4 SDK2 ETV1 LAMA2 SLC40A1	2.14e-06	197	85	6	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	PCW_10-12-Mesenchymal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 GUCY1A2 FAT3 ETV1 LAMA2 SLC40A1	2.27e-06	199	85	6	a09292de4c4447b8eee55d401808e43b817321cc
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	ADAMTS12 CRIM1 GUCY1A2 DOCK11 OTOGL LAMA2	2.34e-06	200	85	6	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 GUCY1A2 LAMA2 BEND2 TULP2	8.65e-06	145	85	5	051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMC2 OTOGL FAT3 ATP6V0D2 HYDIN	1.48e-05	162	85	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRDC SLC26A7 ATP6V0D2 PLCH1 GLCCI1	2.14e-05	175	85	5	1d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB1 P2RY1 BCORL1 LAMA2 ATP6V0D2	2.20e-05	176	85	5	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ADAMTS12 DCHS2 GUCY1A2 SLC26A7 BEND2	2.20e-05	176	85	5	2015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	CRIM1 GUCY1A2 DOCK11 LAMA2 RUNDC1	2.45e-05	180	85	5	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	SDK2 FAT3 BCORL1 ITGA5 RUNDC1	2.59e-05	182	85	5	ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL FAT3 PLCH1 HYDIN OTOG	2.73e-05	184	85	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL FAT3 PLCH1 HYDIN OTOG	2.73e-05	184	85	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL FAT3 PLCH1 HYDIN OTOG	2.73e-05	184	85	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 DLGAP1 DCHS2 GUCY1A2 LAMA2	3.18e-05	190	85	5	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 DLGAP1 DCHS2 GUCY1A2 LAMA2	3.18e-05	190	85	5	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	ADAMTS12 DOCK4 FAT3 ETV1 SLC40A1	3.18e-05	190	85	5	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 DLGAP1 DCHS2 GUCY1A2 LAMA2	3.26e-05	191	85	5	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 DLGAP1 SDK2 GUCY1A2 FAT3	3.26e-05	191	85	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 DLGAP1 DCHS2 GUCY1A2 LAMA2	3.34e-05	192	85	5	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 DLGAP1 DCHS2 GUCY1A2 LAMA2	3.34e-05	192	85	5	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 DLGAP1 SDK2 GUCY1A2 FAT3	3.34e-05	192	85	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS12 DOCK4 DLGAP1 FAT3 LAMA2	3.42e-05	193	85	5	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	ADAMTS12 DLGAP1 SDK2 FAT3 LAMA2	3.42e-05	193	85	5	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS12 DOCK4 DLGAP1 FAT3 LAMA2	3.51e-05	194	85	5	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 DLGAP1 SDK2 GUCY1A2 FAT3	3.51e-05	194	85	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	368C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 CRIM1 FAT3 ETV1 SLC40A1	3.51e-05	194	85	5	d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 DLGAP1 SDK2 GUCY1A2 FAT3	3.51e-05	194	85	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	368C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 CRIM1 FAT3 ETV1 SLC40A1	3.51e-05	194	85	5	e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 DLGAP1 GUCY1A2 ETV1 LAMA2	3.60e-05	195	85	5	c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTS12 CRIM1 FAT3 LAMA2 SLC40A1	3.60e-05	195	85	5	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 SDK2 FAT3 ETV1 SLC40A1	3.69e-05	196	85	5	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 SDK2 FAT3 ETV1 SLC40A1	3.69e-05	196	85	5	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 DOCK4 FAT3 LAMA2 SLC40A1	3.69e-05	196	85	5	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 DOCK4 FAT3 LAMA2 SLC40A1	3.78e-05	197	85	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	DOCK4 CRIM1 P2RY1 ETV1 SLC40A1	3.78e-05	197	85	5	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ADAMTS12 DOCK4 SDK2 ETV1 SLC40A1	3.96e-05	199	85	5	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 DOCK4 FAT3 LAMA2 SLC40A1	4.06e-05	200	85	5	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ADAMTS12 SDK2 FAT3 LAMA2 SLC40A1	4.06e-05	200	85	5	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAMTS12 SDK2 FAT3 LAMA2 SLC40A1	4.06e-05	200	85	5	a510deaada669e690329183e18df02870bd204b3
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 FAT3 ETV1 LAMA2 SLC40A1	4.06e-05	200	85	5	cb31cfcfa8e6d6cc610c4c22e97bc009dd8a9e7c
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAMTS12 SDK2 FAT3 LAMA2 SLC40A1	4.06e-05	200	85	5	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A7 ATP6V0D2 PLCH1 LRRC4	1.90e-04	149	85	4	cc911b454fe4e4b489885b9920baa7eb01a027ba
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)\|Striatum / BrainAtlas - Mouse McCarroll V32	OTP SLC26A7 UHMK1	1.96e-04	59	85	3	a72de8cda377c87fa9a6fbda72735d850650f9f4
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	OTP SLC26A7 UHMK1	1.96e-04	59	85	3	3ab024fa7a927177da0dc764cee46dabdd008040
ToppCell	droplet-Liver-Npc-21m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB1 KLHDC8B SBNO2 FANCA	2.32e-04	157	85	4	264b22d0ffc43049161843bb55d2eccbf5fca575
ToppCell	droplet-Liver-Npc-21m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB1 KLHDC8B SBNO2 FANCA	2.32e-04	157	85	4	67945d37027be62c880d3072afa7ca7e97c76c20
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A7 LAMA2 ATP6V0D2 GLCCI1	2.32e-04	157	85	4	c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK3 TMC2 SLC26A7 HYDIN	2.32e-04	157	85	4	370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ATP6V0D2 LRRC4 SLC40A1	2.38e-04	158	85	4	12661763d1c309106801cb710c04cd2b62d16cba
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ATP6V0D2 LRRC4 SLC40A1	2.38e-04	158	85	4	e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ATP6V0D2 LRRC4 SLC40A1	2.38e-04	158	85	4	0792c39e6fc0745095af7812de2d50949540d60f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 DCHS2 GUCY1A2 LAMA2	2.43e-04	159	85	4	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	ADAMTS12 SDK2 LAMA2 SLC40A1	2.43e-04	159	85	4	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 DCHS2 GUCY1A2 LAMA2	2.43e-04	159	85	4	2607b562903228274fbd96168ba826782fab0b53
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR64 FAT3 LAMA2 HYDIN	2.49e-04	160	85	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MKNK2 ITGA5 LRRC4 OTOG	2.49e-04	160	85	4	33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR64 FAT3 LAMA2 HYDIN	2.49e-04	160	85	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 GUCY1A2 LAMA2 LRRC4	2.55e-04	161	85	4	82ed45f144a07856fe92d37426c5f92e259a03a9
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CRIM1 GAB3 PGLYRP2 GLCCI1	2.55e-04	161	85	4	a480107b1c7773f2081afca2657e0b7fc88a5645
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 GUCY1A2 LAMA2 BEND2	2.68e-04	163	85	4	bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 GUCY1A2 LAMA2 BEND2	2.68e-04	163	85	4	8e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	ADAMTS12 SDK2 LAMA2 SLC40A1	2.74e-04	164	85	4	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	GUCY1A2 LAMA2 BEND2 LRRC4	2.87e-04	166	85	4	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GUCY1A2 LAMA2 BEND2 LRRC4	2.87e-04	166	85	4	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 FAT3 FPR2 SLC40A1	3.07e-04	169	85	4	bca5322880c09b78ef10d9dda6420a80c1ba7e62
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL FAT3 PLCH1 HYDIN	3.07e-04	169	85	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GUCY1A2 OTOGL LAMA2 PLCH1	3.14e-04	170	85	4	3174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DCHS2 GUCY1A2 OTOGL FAT3	3.14e-04	170	85	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 GUCY1A2 LAMA2 FANCA	3.21e-04	171	85	4	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 GUCY1A2 LAMA2 FANCA	3.21e-04	171	85	4	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OTOGL FAT3 ETV1 PLCH1	3.21e-04	171	85	4	f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	USP28 BCORL1 ATP6V0D2 SLC40A1	3.28e-04	172	85	4	eba1568d4307e91c94fc616549057cbed8df5840
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SDK2 FAT3 ETV1 ATP6V0D2	3.35e-04	173	85	4	f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL VGLL2 HYDIN SBNO2	3.43e-04	174	85	4	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 MTOR DOP1A FANCA	3.43e-04	174	85	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 SDK2 ETV1 ST14	3.43e-04	174	85	4	7d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A7 LAMA2 ATP6V0D2 GLCCI1	3.50e-04	175	85	4	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 FAT3 GLCCI1 HYDIN	3.66e-04	177	85	4	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OTOGL FAT3 LAMA2 PLCH1	3.74e-04	178	85	4	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OTOGL FAT3 LAMA2 PLCH1	3.82e-04	179	85	4	8766a5a066091879f521acfc612abf563ff78808
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRDC SLC26A7 ATP6V0D2 GLCCI1	3.82e-04	179	85	4	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 SDK2 GUCY1A2 LAMA2	3.82e-04	179	85	4	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS12 PHLDB1 SDK2 GUCY1A2	3.82e-04	179	85	4	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 SDK2 GUCY1A2 LAMA2	3.82e-04	179	85	4	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	WDR90 LRRC4 MUC5AC HYDIN	3.90e-04	180	85	4	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY1 FAT3 PGLYRP2 ST14	3.90e-04	180	85	4	41e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PHLDB1 CRIM1 GUCY1A2 OTOGL	3.98e-04	181	85	4	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 GUCY1A2 FAT3 LAMA2	3.98e-04	181	85	4	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 FAT3 GLCCI1 HYDIN	3.98e-04	181	85	4	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLIP4 DCHS2 CRIM1 DOCK11	3.98e-04	181	85	4	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS12 DLGAP1 FAT3 LAMA2	3.98e-04	181	85	4	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 GUCY1A2 FAT3 LAMA2	3.98e-04	181	85	4	c62b0a2422377ffadaab63edd538e87a06fa5017
Disease	skin sensitivity to sun	ADAMTS12 HERC2 FANCA	1.80e-05	19	80	3	EFO_0004795
Disease	rosacea severity measurement	MICB ATP6V0D2 HERC2 CAMTA1 FANCA	5.10e-05	147	80	5	EFO_0009180
Disease	polybrominated biphenyl measurement, gestational serum measurement, polybrominated diphenyl ether measurement	DLGAP1 MICB	7.22e-05	5	80	2	EFO_0007961, EFO_0007962, EFO_0007964
Disease	endoplasmic reticulum aminopeptidase 1 measurement	ERAP2 ERAP1	1.51e-04	7	80	2	EFO_0008119
Disease	severe pre-eclampsia (is_marker_for)	ERAP2 ERAP1	2.01e-04	8	80	2	DOID:13129 (is_marker_for)
Disease	frontal fibrosing alopecia	ERAP2 ERAP1 ETV1	3.04e-04	48	80	3	EFO_0009855
Disease	periodontitis	GVINP1 FAT3 BCORL1 LAMA2 CAMTA1	3.58e-04	223	80	5	EFO_0000649
Disease	hair colour measurement, hair morphology measurement	HERC2 FANCA	4.71e-04	12	80	2	EFO_0007821, EFO_0007822
Disease	skin pigmentation measurement	ADAMTS12 HERC2 HYDIN FANCA	5.35e-04	137	80	4	EFO_0007009
Disease	Schizophrenia	ADAMTS12 DOCK4 DLGAP1 SLC26A7 MTOR MICB UHMK1 LAMA2 SBNO2	6.41e-04	883	80	9	C0036341
Disease	Nonsyndromic Deafness	OTOGL TSPEAR OTOG	1.41e-03	81	80	3	C3711374
Disease	neuroimaging measurement	DCHS2 FAT3 IPP LAMA2 CAMTA1 PLCH1 SLC40A1 GLCCI1 SH2D5	2.41e-03	1069	80	9	EFO_0004346

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSPANPESSMEDCLA	BCL2L13	91	Q9BXK5
IPETTMNFDPDCFLN	CAMTA1	476	Q9Y6Y1
RLMCTGSQTFDSFPP	EFL1	376	Q7Z2Z2
FKIAGDMRATCPAFN	GVINP1	2106	Q7Z2Y8
SLSRVCFPAAQAPAM	BCORL1	416	Q5H9F3
SCPGPMARQFSRDAS	DLGAP1	721	O14490
LFCFPFHMSQATRPD	DOP1A	251	Q5JWR5
EMASRQPISAPLFSC	GLCCI1	431	Q86VQ1
MAANVFPFRDARAAP	ACTR5	1	Q9H9F9
SAAPMPSDCEFSFFD	CLIP4	36	Q8N3C7
PTFRQMQCSEFDTVP	ADAMTS12	601	P58397
TALEPSFCSIFNMPT	ABHD8	281	Q96I13
MANEDCPKAADSPFS	IPP	1	Q9Y573
SAPTFPLCAMQLFSH	NCSTN	206	Q92542
AVPAAKMPAFSSCFE	OTUD1	66	Q5VV17
ARLDFQTPAMCAFND	P2RY1	286	P47900
PITMSFPFCNSREIN	OR2T1	211	O43869
VFDPRRSASMFAVGC	MPV17L2	56	Q567V2
AMIAPVECPSFSSAA	HERC2	3421	O95714
CRFSPMYPTASASIE	GAB3	376	Q8WWW8
PTSSLAFFNSCLNPM	FPR2	286	P25090
RALSSFCFHPNLEMP	BEND2	291	Q8NDZ0
QFEPTAARMAFPCFD	ERAP1	181	Q9NZ08
AARMAFPCFDEPAFK	ERAP1	186	Q9NZ08
SSARRACQFPAPMAA	LENG9	11	Q96B70
SDFGLQCSARPDMPA	MKNK2	36	Q9HBH9
TPVTMQFPFCASREI	OR2T7	151	P0C7T2
APPCTDFTRCAANMR	PGLYRP2	416	Q96PD5
CDPEALFSMAFPDNQ	ETV1	416	P50549
ASFQCSAPFIMDAPR	LRRC4	346	Q9HBW1
SVPMDFARPVSFKNA	LAMA2	2691	P24043
QRTDFPYVSAAMPCF	MICB	306	Q29980
QAPAPVCAAPMVFFD	MUC5AC	796	P98088
CALAFTRMPGFQTPS	METTL25B	96	Q96FB5
PVTMQFPFCASREIN	OR2T27	161	Q8NH04
FGSARLLSNPMAFAC	NEK3	146	P51956
APQFMFSSFSCIVPE	DCHS2	2766	Q6V1P9
IFPAMFNPEERSCSL	ITGA5	501	P08648
FSFQPVCKAEMSPSE	IL37	201	Q9NZH6
NMTPPTSALGACFVF	HYDIN	496	Q4G0P3
EFSAFDMSAPTPARC	ATG7	66	O95352
LDFPNFSPMASQENC	BICRAL	1036	Q6AI39
AAMPNSASRDEFPCG	DOCK11	1191	Q5JSL3
EFSACMQASPVHFPN	DOCK4	1591	Q8N1I0
DLDSPFFGIRPAFMC	ENTR1	46	Q96C92
FCQNLMAASSVAPPE	FANCA	726	O15360
FFRLCQQSMDPTAFP	DLGAP3	851	O95886
PPASCEFSTFAVSMN	FAT3	4476	Q8TDW7
RTCSNPFEFPSQDMC	CRIM1	146	Q9NZV1
VTDFEPTQARMAFPC	ERAP2	196	Q6P179
PSLPSRRAFAGCAMA	KLHDC8B	206	Q8IXV7
SPTNPGFMTCSDDFR	CSTF1	406	Q05048
MEVPDLNPFTCYSFR	SDK2	1056	Q58EX2
PCSSGMPAFEAIFFK	OTOGL	306	Q3ZCN5
LPQFPSAAAAAAAAM	OTP	181	Q5XKR4
LTGEMFAPCSAFLSP	OTOG	716	Q6ZRI0
NPMARDLFNAAFVSC	MTOR	1311	P42345
NTFCRAFPFHLMFDP	GUCY1A2	321	P33402
IACLLPAFSSAPEAM	RUNDC1	456	Q96C34
PLGFTFSFPCRQMSI	HKDC1	596	Q2TB90
MAAPIPQGFSCLSRF	MRPL45	1	Q9BRJ2
MEPFSCDTFVALPPA	SCRN3	1	Q0VDG4
DCQFAFMARNPRSPA	SH2D5	101	Q6ZV89
FQAISHSFQMDPPFC	SNX33	421	Q8WV41
HSFQMDPPFCSEALN	SNX33	426	Q8WV41
RPFMSSASFLGSQPC	SBNO2	56	Q9Y2G9
EPTCASQMAEPFRTF	SLC40A1	281	Q9NP59
PEPSAAMLFVCSRSG	WDR90	566	Q96KV7
DTFTMDFCFPFSPLQ	TULP2	496	O00295
DCSFPMSQRSFPASF	VGLL2	131	Q8N8G2
NFRMFSCPEESDPIQ	ZSCAN5B	46	A6NJL1
GFEATFFQLPRMSSC	ST14	326	Q9Y5Y6
CFPARSPFVLIMSDT	VN1R1	316	Q9GZP7
CEDSAAARPFPILAM	NRDC	36	O43847
PNSPYDLCSRFAAVM	USP28	1051	Q96RU2
FTMVTESPNPALTFC	PHLDB1	1326	Q86UU1
EGFTNFMRSPACDIF	PLCH1	276	Q4KWH8
SAFGKMFNRCTDLAP	ZNF630	156	Q2M218
PRTMSFPASRIFSQC	TSPEAR	66	Q8WU66
MFCPPLFETIAALEN	TMC2	481	Q8TDI7
FFFCIPSAAAMGRTA	SLC26A7	356	Q8TE54
DLSPPAMAAFDLACS	ZFYVE26	966	Q68DK2
EMALCSPFFSIPFAP	UHMK1	296	Q8TAS1
GDDSPTTLCSFFPRM	SHC1	51	P29353
SCDTDDFVMVPAQFP	ULK1	351	O75385
PVREFSMPRGANTFC	WDR64	316	B1ANS9
IETPLAPFFQDCMSE	ATP6V0D2	156	Q8N8Y2
PQTMFPSASECNAFP	PP6455	36	Q8WZ26