Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone deacetylase binding

LPIN1 MAGEA11 SATB2 PER2 CHD5 HDAC1

4.74e-05147886GO:0042826
DomainSCA7

ATXN7 ATXN7L1

1.28e-044872PF08313
DomainSCA7

ATXN7 ATXN7L1

1.28e-044872PS51505
DomainSCA7_dom

ATXN7 ATXN7L1

1.28e-044872IPR013243
DomainAWS

NSD2 NSD3

2.13e-045872SM00570
DomainAnaphylatoxin_comp_syst

C4A C4B

2.13e-045872IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

2.13e-045872IPR001840
DomainAWS

NSD2 NSD3

2.13e-045872PS51215
DomainAWS_dom

NSD2 NSD3

2.13e-045872IPR006560
DomainZinc_finger_PHD-type_CS

NSD2 CHD5 NFX1 NSD3

2.39e-0465874IPR019786
DomainANATO

C4A C4B

4.44e-047872SM00104
DomainANATO

C4A C4B

4.44e-047872PF01821
DomainANAPHYLATOXIN_2

C4A C4B

4.44e-047872PS01178
DomainANAPHYLATOXIN_1

C4A C4B

4.44e-047872PS01177
DomainAnaphylatoxin/fibulin

C4A C4B

4.44e-047872IPR000020
DomainZnf_PHD-finger

NSD2 CHD5 NFX1 NSD3

5.06e-0479874IPR019787
DomainThiol-ester_cl

C4A C4B

5.90e-048872PF10569
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

5.90e-048872IPR019565
DomainMacrogloblnA2_CS

C4A C4B

5.90e-048872IPR019742
DomainPTPc

PTPN13 PTPRD PTPRS

6.24e-0436873SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN13 PTPRD PTPRS

7.90e-0439873PS50055
DomainPTPase_domain

PTPN13 PTPRD PTPRS

9.16e-0441873IPR000242
DomainY_phosphatase

PTPN13 PTPRD PTPRS

9.16e-0441873PF00102
DomainA2M_N

C4A C4B

9.42e-0410872PF01835
DomainA2M_N

C4A C4B

9.42e-0410872IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

9.42e-0410872IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

9.42e-0410872PS00477
DomainA2M

C4A C4B

9.42e-0410872PF00207
DomainA2M_N_2

C4A C4B

9.42e-0410872IPR011625
DomainA2M_comp

C4A C4B

9.42e-0410872IPR011626
DomainA2M_N_2

C4A C4B

9.42e-0410872PF07703
DomainA2M_recep

C4A C4B

9.42e-0410872PF07677
DomainA2M_comp

C4A C4B

9.42e-0410872PF07678
DomainMacroglobln_a2

C4A C4B

9.42e-0410872IPR001599
Domain-

CASP8AP2 SATB2 LMX1A LMX1B DEK TLX1

2.08e-032838761.10.10.60
DomainPost-SET_dom

NSD2 NSD3

2.47e-0316872IPR003616
DomainPostSET

NSD2 NSD3

2.47e-0316872SM00508
DomainPOST_SET

NSD2 NSD3

2.47e-0316872PS50868
DomainPTPc_motif

PTPN13 PTPRD PTPRS

2.63e-0359873SM00404
DomainTyr_Pase_cat

PTPN13 PTPRD PTPRS

2.63e-0359873IPR003595
DomainC345C

C4A C4B

2.79e-0317872SM00643
DomainTerpenoid_cyclase/PrenylTrfase

C4A C4B

3.13e-0318872IPR008930
DomainNTR

C4A C4B

3.48e-0319872PF01759
DomainNetrin_module_non-TIMP

C4A C4B

3.48e-0319872IPR018933
DomainPWWP

NSD2 NSD3

3.86e-0320872SM00293
DomainLIM

ABLIM1 LMX1A LMX1B

4.10e-0369873PF00412
Domain-

ABLIM1 LMX1A LMX1B

4.27e-03708732.10.110.10
DomainZnf_LIM

ABLIM1 LMX1A LMX1B

4.44e-0371873IPR001781
DomainLIM_DOMAIN_1

ABLIM1 LMX1A LMX1B

4.44e-0371873PS00478
DomainLIM_DOMAIN_2

ABLIM1 LMX1A LMX1B

4.44e-0371873PS50023
DomainLIM

ABLIM1 LMX1A LMX1B

4.44e-0371873SM00132
DomainHomeodomain-like

CASP8AP2 SATB2 LMX1A LMX1B DEK TLX1

4.56e-03332876IPR009057
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

LIG3 SETX CENPC NSD2 ZNF644 CHD5 GPATCH4 MSH3 DEK PPM1G NSD3 HDAC1 PAPOLG

5.24e-09608891336089195
Pubmed

The histone methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1-mediated transcriptional repression.

NSD2 NSD3 HDAC1

1.62e-08389317239852
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ABLIM1 CAMKK2 RIPOR2 PER2 SUGP2 ZNF644 SPHKAP SORBS1 MTCL1 SIPA1L2

9.64e-08407891012693553
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CASP8AP2 LIG3 RNMT SUGP2 CENPC PUF60 NSD2 NUP98 MSH3 DEK PPM1G NSD3 HDAC1 NOSIP

2.94e-071014891432416067
Pubmed

Tectorin-beta (Tectb) maps to mouse chromosome 19.

ABLIM1 TECTB TLX1

3.22e-0768939799617
Pubmed

A human MAP kinase interactome.

CASP8AP2 ABLIM1 RIPOR2 SETX MYO9A NUP98 C4A SORBS1 NKTR NSD3

4.91e-07486891020936779
Pubmed

Protection from Streptococcus pneumoniae infection by C-reactive protein and natural antibody requires complement but not Fc gamma receptors.

FCGR2A C4A C4B

5.63e-07789312055255
Pubmed

Divergent immunoglobulin g subclass activity through selective Fc receptor binding.

FCGR2A C4A C4B

8.99e-07889316322460
Pubmed

Impaired antibody response causes persistence of prototypic T cell-contained virus.

FCGR2A C4A C4B

8.99e-07889319355789
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ABLIM1 PTPN13 SETX MYO9A PLEKHG3 HJURP SORBS1 MTCL1 SIPA1L2 RFX7 TAB3 NSD3

2.03e-06861891236931259
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPN13 PTPRD PTPRS

2.63e-06118937832766
Pubmed

The mouse adducin gene family: alternative splicing and chromosomal localization.

ABLIM1 TECTB TLX1

2.63e-061189310602987
Pubmed

Interaction network of human early embryonic transcription factors.

LIG3 SATB2 ZNF644 NAB1 NUP98 MSH3 RFX7 HDAC1

3.45e-0635189838297188
Pubmed

The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.

FCGR2A C4A C4B

3.50e-061289331801071
Pubmed

ATRX proximal protein associations boast roles beyond histone deposition.

CENPC NSD2 ZNF644 NSD3 HDAC1

3.83e-069189534780483
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HEG1 PER2 CELSR2 SUGP2 LMX1B PTPRS PUF60 NSD2 CHD5 OSBPL5 NFX1 SIPA1L2 NSD3

4.71e-061105891335748872
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

THAP4 CASP8AP2 LIG3 SETX NSD2 ZNF644 NUP98 GPATCH4 NKTR MSH3 RFX7 DEK NSD3 HDAC1

5.12e-061294891430804502
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

THAP4 ABLIM1 PTPN13 SUGP2 MYO9A ATXN7 PTPRS ATXN7L1 NSD2 PLEKHG3 OSBPL5 TTC14 ARHGEF18 RIMS1 MCTP2

5.37e-061489891528611215
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

LIG3 SETX SUGP2 CENPC PUF60 NSD2 ZNF644 NUP98 GPATCH4 DEK NSD3 NOSIP

5.79e-06954891236373674
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

6.48e-06289222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

6.48e-06289216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

6.48e-06289215998580
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

6.48e-0628927373044
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

6.48e-06289219062096
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

6.48e-0628923696167
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

6.48e-0628921357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

6.48e-06289216098595
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

6.48e-06289219933335
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

6.48e-0628922459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

6.48e-06289217645767
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

6.48e-06289215787745
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

6.48e-06289212207352
Pubmed

Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions.

ATXN7 SORBS1

6.48e-06289211371513
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

6.48e-06289230026462
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

6.48e-0628926559257
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

6.48e-06289227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

6.48e-06289222387014
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

6.48e-06289234299197
Pubmed

Assessment of complement C4 gene copy number using the paralog ratio test.

C4A C4B

6.48e-06289220506482
Pubmed

Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.

C4A C4B

6.48e-06289212480675
Pubmed

Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.

C4A C4B

6.48e-06289226800705
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

6.48e-06289223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

6.48e-06289223918728
Pubmed

Murine complement C4 is not required for experimental autoimmune encephalomyelitis.

C4A C4B

6.48e-06289215390104
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

6.48e-0628923037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

6.48e-06289211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

6.48e-0628924216347
Pubmed

Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.

C4A C4B

6.48e-0628921699796
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

6.48e-0628926950384
Pubmed

Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.

C4A C4B

6.48e-0628922997024
Pubmed

NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).

NUP98 NSD3

6.48e-06289211986249
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

6.48e-0628928660986
Pubmed

Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.

C4A C4B

6.48e-0628923624865
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

6.48e-0628928428773
Pubmed

Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.

C4A C4B

6.48e-06289221857912
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

6.48e-06289224638111
Pubmed

Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.

C4A C4B

6.48e-0628926208559
Pubmed

The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.

C4A C4B

6.48e-0628924514997
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

6.48e-06289221345967
Pubmed

The inheritance of susceptibility to the Gross leukemia virus in mice.

C4A C4B

6.48e-0628925919331
Pubmed

An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.

C4A C4B

6.48e-0628923167981
Pubmed

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.

C4A C4B

6.48e-0628927545960
Pubmed

Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.

C4A C4B

6.48e-06289230041577
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

6.48e-0628922572548
Pubmed

The complement component C4 of mammals.

C4A C4B

6.48e-0628922302180
Pubmed

Complete cDNA sequence of the fourth component of murine complement.

C4A C4B

6.48e-0628923862104
Pubmed

Targeting H3K36 methyltransferases NSDs: a promising strategy for tumor targeted therapy.

NSD2 NSD3

6.48e-06289234083510
Pubmed

The BS variant of C4 protects against age-related loss of white matter microstructural integrity.

C4A C4B

6.48e-06289234358307
Pubmed

Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.

C4A C4B

6.48e-06289218360261
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

6.48e-06289222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

6.48e-06289218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

6.48e-06289229080553
Pubmed

Identification of a human LMX1 (LMX1.1)-related gene, LMX1.2: tissue-specific expression and linkage mapping on chromosome 9.

LMX1A LMX1B

6.48e-0628929441763
Pubmed

Schizophrenia risk from complex variation of complement component 4.

C4A C4B

6.48e-06289226814963
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

6.48e-0628926589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

6.48e-06289225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

6.48e-06289217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

6.48e-0628926149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

6.48e-0628926149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

6.48e-06289212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

6.48e-0628923542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

6.48e-0628922387317
Pubmed

Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.

C4A C4B

6.48e-0628928132550
Pubmed

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

C4A C4B

6.48e-0628922395880
Pubmed

Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.

C4A C4B

6.48e-06289226814708
Pubmed

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).

C4A C4B

6.48e-0628926192448
Pubmed

Complete primary structure of human C4a anaphylatoxin.

C4A C4B

6.48e-0628926167582
Pubmed

Do polymorphisms in transcription factors LMX1A and LMX1B influence the risk for Parkinson's disease?

LMX1A LMX1B

6.48e-06289219189040
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

6.48e-06289216908004
Pubmed

Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.

C4A C4B

6.48e-0628921438267
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

6.48e-0628927365238
Pubmed

Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.

C4A C4B

6.48e-06289219150565
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

6.48e-0628927391573
Pubmed

Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.

C4A C4B

6.48e-06289217506029
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

6.48e-06289217971360
Pubmed

Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.

C4A C4B

6.48e-06289223715124
Pubmed

Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.

C4A C4B

6.48e-0628923464002
Pubmed

Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.

C4A C4B

6.48e-0628922993295
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

6.48e-06289229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

6.48e-06289217971229
InteractionCENPA interactions

LIG3 CENPC NSD2 ZNF644 HJURP GPATCH4 MSH3 DEK PPM1G NSD3 HDAC1

7.49e-073778811int:CENPA
InteractionSNRNP40 interactions

CASP8AP2 SETX SUGP2 CENPC NSD2 ZNF644 ZNF667 TTC14 GPATCH4 NKTR NSD3 NOSIP PAPOLG

3.79e-066378813int:SNRNP40
InteractionH3C3 interactions

LIG3 SETX CENPC NSD2 ZNF644 CHD5 GPATCH4 MSH3 DEK NSD3 HDAC1

1.02e-054958811int:H3C3
InteractionH3-3A interactions

LIG3 CENPC PUF60 NSD2 ZNF644 CHD5 OSBPL5 MSH3 DEK PPM1G NSD3 HDAC1 PAPOLG

2.14e-057498813int:H3-3A
InteractionIER5 interactions

PPP2R2D MYO9A MTCL1

2.23e-0513883int:IER5
InteractionTERF2IP interactions

LIG3 SETX SUGP2 CENPC PUF60 NSD2 ZNF644 GPATCH4 MSH3 PPM1G NSD3

2.80e-055528811int:TERF2IP
InteractionH2BC8 interactions

ESCO2 LIG3 CENPC NSD2 ZNF644 GPATCH4 MSH3 DEK PPM1G NSD3 NOSIP

4.13e-055768811int:H2BC8
InteractionKLF6 interactions

CELSR2 ATXN7 ATXN7L1 ZNF644 HDAC1

6.02e-0595885int:KLF6
InteractionYWHAH interactions

ABLIM1 PTPN13 SETX MYO9A PLEKHG3 HJURP OSBPL5 SORBS1 NKTR RIMS1 MTCL1 SIPA1L2 RFX7 TAB3 NSD3

7.86e-0511028815int:YWHAH
InteractionNUP43 interactions

CASP8AP2 LIG3 SETX CENPC NSD2 ZNF644 TTC14 NUP98 GPATCH4 NKTR NSD3

8.58e-056258811int:NUP43
Cytoband1p21

COL11A1 CELSR2

9.98e-04248921p21
CytobandEnsembl 112 genes in cytogenetic band chr2q37

THAP4 PER2 HJURP DGKD

1.01e-03226894chr2q37
CytobandEnsembl 112 genes in cytogenetic band chr1q23

FCGR2A LMX1A GPATCH4 FCRL6

1.01e-03226894chr1q23
GeneFamilyPHD finger proteins

NSD2 CHD5 NFX1 NSD3

1.98e-049058488
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

3.59e-0495821234
GeneFamilyPHD finger proteins|NuRD complex

CHD5 HDAC1

6.54e-04125821305
GeneFamilyLIM class homeoboxes

LMX1A LMX1B

6.54e-0412582522
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRD PTPRS

2.04e-0321582813
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

SUGP2 GPATCH4

2.24e-0322582579
GeneFamilyPWWP domain containing

NSD2 NSD3

2.24e-03225821147
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG3 OSBPL5 ARHGEF18 DGKD

4.30e-03206584682
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD2 NSD3

5.31e-0334582487
GeneFamilyComplement system|Sushi domain containing

C4A C4B

5.94e-0336582492
GeneFamilyGlycosyltransferase family 6|Blood group antigens

C4A C4B

6.27e-0337582454
GeneFamilyPDZ domain containing

PTPN13 RIMS1 SIPA1L2

1.28e-021525831220
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PTPRD PTPRS JAM2

1.50e-02161583593
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG3 ARHGEF18

1.90e-0266582722
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CASP8AP2 PTPN13 SETX RNMT CENPC MYO9A ZNF644 N4BP2L2 HAUS3 NKTR MSH3 DEK ZNF654

3.30e-076568913M18979
CoexpressionGSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP

LPIN1 RIPOR2 LMX1B ATXN7 ARHGEF18 HAUS3 NKTR

5.15e-06198897M5293
CoexpressionPASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN

CAMKK2 RIPOR2 ATXN7L1 ARHGEF18 RFX7 DEK

2.71e-05172896M17811
CoexpressionPASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN

CAMKK2 RIPOR2 ATXN7L1 ARHGEF18 RFX7 DEK

2.80e-05173896MM580
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ABLIM1 RIPOR2 ATXN7 TTC14 N4BP2L2 NKTR NOSIP

1.32e-07195897d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LPIN1 SUGP2 ZNF644 TTC14 N4BP2L2 NKTR MCTP2

1.51e-07199897f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ZFAT PTPRD MYO9A PTPRS OSBPL5 GPATCH4

1.11e-06168896c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABLIM1 PER2 NSD2 NKTR RIMS1 FER1L6

1.61e-061798966e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMX1A SPHKAP RIMS1 MTCL1 HS3ST2 UNC80

1.95e-06185896cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMX1A SPHKAP RIMS1 MTCL1 HS3ST2 UNC80

1.95e-06185896c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL11A1 PTPN13 CHD5 C4B HMGCS2 FGFBP1

2.08e-061878966f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMX1A SPHKAP RIMS1 MTCL1 HS3ST2 UNC80

2.08e-061878967b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNMT CENPC ZNF644 NUP98 CCDC187 NKTR

2.35e-061918961ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellremission|World / disease stage, cell group and cell class

ABLIM1 RIPOR2 TTC14 N4BP2L2 NKTR NOSIP

2.49e-0619389686cfd0c230ba96a43d343216935952fff6a5254e
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 PER2 TTC14 N4BP2L2 SORBS1 NSD3

2.57e-06194896e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 RIPOR2 CENPC HAUS3 NSD3 NOSIP

2.89e-061988968a7897d98f5296745d9005a7cd777f0a2f78000d
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SETX RNMT CENPC ZNF644 N4BP2L2 NKTR

3.06e-0620089612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ABLIM1 RIPOR2 ARHGEF18 MTCL1 NSD3

1.01e-05143895bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellControl-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ABLIM1 RIPOR2 SETX ARHGEF18 NSD3

1.05e-05144895984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RNMT ATXN7 TTC14 N4BP2L2 NKTR

1.16e-0514789594998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ABLIM1 RIPOR2 SETX ARHGEF18 NSD3

1.50e-051558950a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ABLIM1 RIPOR2 SETX ARHGEF18 NSD3

1.69e-051598952881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 USP51 HJURP NUP98 DEK

1.91e-051638953efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 CENPC NSD2 HJURP DEK

3.07e-051808955e1680088065be14447d5d5465f91f7edd071a1e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SATB2 RIPOR2 PTPRD MYO9A MCTP2

3.15e-051818956956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

RIPOR2 PLEKHG3 OSBPL5 MCTP2 FCRL6

3.49e-05185895755c0998c729f462399f1d5e88adf4bfae31be30
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKK2 SPHKAP RIMS1 MTCL1 UNC80

3.59e-05186895d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMX1A SPHKAP MTCL1 HS3ST2 UNC80

3.59e-05186895d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKK2 SPHKAP RIMS1 MTCL1 UNC80

3.87e-05189895f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEG1 PTPN13 PTPRS C4B HMGCS2

4.07e-051918959214655dca96d766737c9f30b624d7fe7050342e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 RNMT HAUS3 NKTR NOSIP

4.07e-05191895696921a4f160b6b55698652488ed781e855e5e51
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ESCO2 CENPC HJURP HAUS3 DEK

4.07e-05191895f764cc21fef87ebad765011098f647ae1bdf6158
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ABLIM1 CENPC ATXN7 N4BP2L2 NKTR

4.17e-0519289547646d7e4990be85072987f92bf18d52f8da752e
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ABLIM1 RIPOR2 SPHKAP N4BP2L2 NOSIP

4.27e-051938952946e8c9328e356cda3dafe7c86e8de462df37da
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ABLIM1 RIPOR2 SPHKAP N4BP2L2 NOSIP

4.27e-051938951559d25b3f1c4ea268478ac26ba13f166b96f1dc
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKK2 SPHKAP RIMS1 MTCL1 UNC80

4.27e-051938955fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN13 PER2 PTPRS RIMS1 FER1L6

4.38e-051948952172d951896265243d14996eacce5aab5e14e26e
ToppCellT_cells-CD56_dim_CD16+_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

HEG1 PLEKHG3 OSBPL5 MCTP2 FCRL6

4.38e-05194895335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 CENPC NSD2 HJURP DEK

4.60e-0519689520383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellcritical-Epithelial-Secretory|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ABLIM1 PTPN13 PER2 RIMS1 FER1L6

4.60e-051968957da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 CENPC NSD2 HJURP DEK

4.60e-051968950644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LPIN1 SUGP2 TTC14 NKTR MCTP2

4.71e-05197895e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellBL-critical-LOC-Lymphoid-CTL|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CENPC TTC14 HAUS3 NKTR NSD3

4.71e-05197895fb70918867fbd111bb192a797dcafed5f39ea299
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 NSD2 ECSCR HJURP DEK

4.71e-05197895a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 NSD2 ECSCR HJURP DEK

4.71e-051978951c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RIPOR2 PLEKHG3 OSBPL5 MCTP2 FCRL6

4.83e-0519889588bb764b21ca50e56f6c536a2d61d35afd8c3f36
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

HEG1 PLEKHG3 OSBPL5 MCTP2 FCRL6

4.83e-05198895d7053a898e04478c577381085f615edaad3cdc5b
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNMT CENPC ZNF644 NKTR NSD3

4.83e-0519889544417089b62056269cac38d3134ff209c05b7007
ToppCellControl-PLT_4|Control / Disease Group and Platelet Clusters

THAP4 SETX NFX1 N4BP2L2 SORBS1

4.83e-05198895387fd3037fd52e4d4c42de0588767e58af228b59
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

HEG1 PLEKHG3 OSBPL5 MCTP2 FCRL6

4.83e-05198895aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNMT CENPC ZNF644 NKTR NSD3

4.83e-0519889528ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTPN13 PTPRS N4BP2L2 NKTR RIMS1

4.94e-051998953d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ESCO2 CENPC PPP2R2D NSD2 HJURP

5.06e-052008954cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIPOR2 ARHGEF18 MTCL1 NSD3

1.38e-04131894a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCellSevere-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ABLIM1 RIPOR2 SETX NSD3

1.79e-04140894683ee5e103f0c68cbbec019249404d381dbc39f3
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ZFAT TECTB HMGCS2 FGFBP1

1.89e-041428946a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ZFAT TECTB HMGCS2 FGFBP1

1.89e-04142894671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ZFAT TECTB HMGCS2 FGFBP1

1.89e-041428943557084150670fd2e2634fc674f228ab85181b59
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ZFAT TECTB HMGCS2 FGFBP1

1.89e-04142894a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMX1B SPHKAP TECTB HS3ST2

2.21e-04148894dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIG3 CENPC NAB1 MSH3

2.27e-0414989465778f19599b4955c0a16f0121237656449431fb
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SATB2 LMX1A LMX1B CHD5

2.63e-04155894498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FCGR2A TMIGD3 HS3ST2

2.73e-0463893d8308a11cc01252b678f2e3247ee3a028221e04c
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3|blood / Manually curated celltypes from each tissue

PTPRD CHD5 ZNF727 MTCL1

2.77e-04157894eb2520c237543ea4869d4386afc0457b111f6193
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LPIN1 SATB2 RIPOR2 MYO9A

2.83e-041588941cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPHKAP FAM181A RIMS1 UNC80

2.90e-041598947747cef94c55144fddcd024a7495318357f1351b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 SPHKAP TECTB UNC80

2.97e-04160894c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 SPHKAP TECTB UNC80

2.97e-0416089425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SATB2 LMX1B CHD5 RIMS1

3.04e-0416189469f5e759c0925daa37e0177a9cc3154842906bf6
ToppCellSevere-B_naive-11|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RIPOR2 RNMT TTC14 NSD3

3.04e-04161894ad3b58e3a8b59a609c8d2d2690d15218d18eabbd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN13 CORO2B CCDC187 HMGCS2

3.12e-04162894285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMX1B SPHKAP RIMS1 UNC80

3.26e-04164894be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SATB2 RIPOR2 NAB1 MTCL1

3.26e-04164894382e42701779d12a7948690b3be72d06dd75c8b4
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGS14 RNMT MTCL1 TEFM

3.34e-04165894475905d608fac628960188ae4a18010b8097417e
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SATB2 LMX1B CHD5 RIMS1

3.34e-041658946d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SATB2 LMX1B CHD5 RIMS1

3.34e-0416589402cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMX1A SPHKAP HS3ST2 UNC80

3.42e-04166894ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 CENPC HJURP MTCL1

3.42e-0416689421ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPN13 CENPC HAUS3 NKTR

3.50e-0416789483969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RIPOR2 SETX ARHGEF18 NSD3

3.50e-04167894948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SATB2 HMGCS2 MCTP2 FGFBP1

3.50e-04167894720dc5855c856b478b5ca90156b30bfcc5518d60
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

ZFAT PTPRS SORBS1 MTCL1

3.50e-04167894bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CORO2B PTPRD LMX1A LMX1B

3.58e-04168894fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ZFAT PTPRS SORBS1 MTCL1

3.58e-04168894968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CORO2B PTPRD LMX1A LMX1B

3.58e-04168894315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell(3)_MNP-(3)_DC_plasmacytoid|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

LPIN1 ZFAT PTPRS MTCL1

3.58e-0416889413c160ea1a19b47d2e7e2dae818c8dcde4e3e377
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CORO2B PTPRD LMX1A LMX1B

3.58e-04168894e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 PTPRD HJURP DEK

3.66e-04169894563c267edaade0e5df192ad953801ef9768d4270
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABLIM1 HEG1 ECSCR JAM2

3.74e-0417089455fe16d98ea284d05fb899888e4569c685644c7b
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 ARHGEF18 DGKD LY75

3.74e-041708943ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

RIPOR2 PLEKHG3 OSBPL5 FCRL6

3.82e-041718941ee505b91f15191d294a5d491ecdf154c08b8622
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

CENPC ATXN7 N4BP2L2 NKTR

3.82e-041718942e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RIPOR2 SETX ARHGEF18 NSD3

3.82e-04171894d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZFAT HJURP LY75 TAB3

3.82e-04171894f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SATB2 RIPOR2 CENPC MCTP2

3.82e-041718942b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SATB2 RIPOR2 CENPC MCTP2

3.82e-04171894dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCelldroplet-Liver-Npc-21m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C8orf88 C4A ZNF654

3.88e-0471893cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CASP8AP2 HJURP ARHGEF18 HMGCS2

3.91e-04172894e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 FCGR2A HJURP DEK

3.91e-04172894ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGS14 RIPOR2 ARHGEF18 FCRL6

3.91e-04172894adf016e5856bc85e7bed58aee09ade483b9dcb00
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2B USP51 HJURP HAUS3

4.00e-0417389460e427f6c7d953cef5f692043670ff0b49cdce72
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CORO2B RNMT CCDC187 DGKD

4.00e-04173894694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellILEUM-inflamed-(1)_T_cell-(1)_T_(gd)|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPRS OSBPL5 MCTP2 FCRL6

4.00e-0417389462f2f42f54c9c6941bf888956be40230f92c883e
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 NSD2 HJURP DEK

4.08e-04174894c988471207ba06195bc3e41056435e8c31c20bbe
DrugDeoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

RGS14 CAMKK2 CORO2B PER2 NSD2 CHD5 MCTP2 NSD3

1.01e-061988886476_UP
Drugpioglitazone HCl; Up 200; 10uM; PC3; HT_HG-U133A

LPIN1 RGS14 SATB2 HEG1 NFX1 SORBS1 NSD3

1.00e-051938876893_UP
DrugCP-320650-01 [172079-28-6]; Up 200; 10uM; PC3; HT_HG-U133A

LIG3 RGS14 SCN11A HEG1 SETX SORBS1 RIMS1

1.07e-051958874557_UP
DrugPicotamide monohydrate [80530-63-8]; Up 200; 10.2uM; HL60; HG-U133A

LIG3 CAMKK2 ATXN7 PLEKHG3 NKTR MSH3 PPM1G

1.26e-052008871387_UP
Diseasespinocerebellar ataxia type 7 (implicated_via_orthology)

ATXN7 ATXN7L1

8.20e-062852DOID:0050958 (implicated_via_orthology)
DiseaseSotos syndrome 1 (implicated_via_orthology)

NSD2 NSD3

2.46e-053852DOID:0112103 (implicated_via_orthology)
Diseasesystemic lupus erythematosus (implicated_via_orthology)

FCGR2A C4A C4B

2.62e-0443853DOID:9074 (implicated_via_orthology)
Diseasesystemic lupus erythematosus (is_implicated_in)

FCGR2A C4A C4B

7.72e-0462853DOID:9074 (is_implicated_in)
Diseasewaist-hip ratio

COL11A1 CAMKK2 ZFAT PTPRD LMX1A PTPRS ATXN7L1 NAB1 RIMS1 RFX7 NOSIP

7.77e-0412268511EFO_0004343
DiseaseLupus Erythematosus, Systemic

FCGR2A C4A C4B

1.14e-0371853C0024141
Diseasesyndrome (implicated_via_orthology)

NSD2 NSD3

1.22e-0318852DOID:225 (implicated_via_orthology)
DiseaseOsteoarthritis of hip

COL11A1 LMX1B

1.51e-0320852C0029410
Diseaseneuropsychological test

CORO2B RIMS1 FER1L6 JAM2

2.56e-03197854EFO_0003926
Diseaseazoospermia (implicated_via_orthology)

PTPRD PTPRS

2.75e-0327852DOID:14227 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KSDKSTSVKRRLSCL

ARHGEF18

251

Q6ZSZ5
PVLREKPKRVKSSSC

CCDC187

241

A0A096LP49
KSSSCKREKTPKLPS

CCDC187

251

A0A096LP49
VRSECSAALGKKSKR

CHD5

311

Q8TDI0
TLSRKRLSCPKEKTT

C4B

661

P0C0L5
CKQSTKTEEKLRPTR

ABLIM1

336

O14639
CRKKRISANSTDPVK

FCGR2A

241

P12318
TRVCRKDFPESSLKL

FGFBP1

136

Q14512
SSKPRASLKPRKVCT

PPP2R2D

391

Q66LE6
KKCLPTISEKSSLLR

CELSR2

2841

Q9HCU4
RRGKSTVCLDKDSRK

CASP8AP2

971

Q9UKL3
DPETKKPCTRSLTCK

ATXN7L1

301

Q9ULK2
ETRRLSLPSSKAKAK

HJURP

481

Q8NCD3
PLSKLKESDRCSASE

MTCL1

1326

Q9Y4B5
AKATKLEKPSRTVTC

NOSIP

171

Q9Y314
KLSSVSICRKKPDFL

C8orf88

86

P0DMB2
PKKCLRTRNVSKSLE

MSH3

121

P20585
KTESSLLPRCLGKSK

HS3ST2

316

Q9Y278
KTSRCLIKSPDRLAD

NUP98

831

P52948
ELKLCSSHSPLRKKR

MCTP2

861

Q6DN12
KKPRATTEVSSRKCQ

MAD2L1BP

111

Q15013
GCSPASIKRKKKRED

MAGEA11

11

P43364
PDKRISICSSDKRIA

HDAC1

401

Q13547
TTKSKCGERDELSPK

NAB1

316

Q13506
SVSRERSEPKKLSLK

FCRL6

281

Q6DN72
DCKKKTTKPLDRSER

COL11A1

181

P12107
STSDLPKRLASRKCV

HMGCS2

441

P54868
ESRACSDGRSRKSKK

GPATCH4

366

Q5T3I0
KLKSKRVKPRDSSES

PER2

796

O15055
KASFEVSSKPCRKVR

LMX1A

211

Q8TE12
SDACKPLKKRNRAST

NSD2

591

O96028
RTKELPCTSLKSEDA

NFX1

666

Q12986
KESSPLSSRKICDKS

LPIN1

291

Q14693
KSKKLSRLTYSSRCP

LY75

1516

O60449
LCKRKSPECDKDTSI

HEG1

1176

Q9ULI3
AILACKTPKKTVSSR

JAM2

46

P57087
KRSLSSSKCDPRHKD

LIG3

246

P49916
DLDTKKPCTRSLTCK

ATXN7

351

O15265
DSKRKDSEPRTKCLL

PTPRS

1311

Q13332
FLPDRSDKSKRRTKT

RIMS1

786

Q86UR5
SRKKRLPSKELPDSS

PAPOLG

701

Q9BWT3
DGSLLTTTCKDKKLR

CORO2B

191

Q9UQ03
TTTCKDKKLRVIEPR

CORO2B

196

Q9UQ03
TTGCRLRKKIKPVTD

EFCAB7

371

A8K855
TKSVPNSTRKIKDTC

CENPC

56

Q03188
KAKRTKCPEILSDES

DEK

216

P35659
SLRFKCRKSKESEDP

ECSCR

146

Q19T08
LKTCKTSDLKTPRLD

HAUS3

81

Q68CZ6
PRKRKQDSLKCDSLL

ESCO2

6

Q56NI9
SSCGKDTPSKKRKLD

RNMT

71

O43148
SQRKVSKSPCEKLIS

DGKD

676

Q16760
LLTKKPTRECESLSE

CAMKK2

516

Q96RR4
TLSRKRLSCPKEKTT

C4A

661

P0C0L4
SDKSKKQCKSPSRRD

PTPN13

1636

Q12923
KRKRAESDSRKSSIP

PTPRD

1291

P23468
SDIKAALDKSAPCRR

FAM181A

81

Q8N9Y4
CVSPTARVTKKETLK

OSBPL5

86

Q9H0X9
RDTSKPTEILTKLCK

FER1L6

1471

Q2WGJ9
TPNVPCRSLKRKKES

SPHKAP

971

Q2M3C7
KIKSCTLARDPTTGK

PUF60

251

Q9UHX1
PSKKDSSDPCTIERK

TAB3

626

Q8N5C8
KSKSERECPHSKKRT

NKTR

846

P30414
EPDRSSCKKKESALS

PLEKHG3

696

A1L390
SCKKKESALSTRDRL

PLEKHG3

701

A1L390
CSSASDKLPRVAKSK

PPM1G

241

O15355
PTEDSCAKKPRSRTK

SATB2

606

Q9UPW6
CAKKPRSRTKISLEA

SATB2

611

Q9UPW6
KPFKRRLKSESVETS

SIPA1L2

276

Q9P2F8
KKSSKLCTCTEPIRK

SETX

1221

Q7Z333
SEKLSCPVTCDKRKR

TECTB

271

Q96PL2
NSILCPKTGREKRKS

TEFM

131

Q96QE5
CEKEAPKSSLLRKQT

SPEM1

66

Q8N4L4
DDILKCKPAVSRSRS

RIPOR2

636

Q9Y4F9
RRAPDSGSKCETKKL

ZNF667

81

Q5HYK9
LKSQSSLSGKPKERC

UHRF1BP1L

1076

A0JNW5
RKSGSCDLNTLRLKK

ZNF727

101

A8MUV8
SGTPETRKRKAKSCI

USP51

221

Q70EK9
CKEDDREKASKRPRS

ZFAT

161

Q9P243
DKSCLRTPSLKKRVS

UNC80

1531

Q8N2C7
SKKSCLKPSDVVRCL

SORBS1

1146

Q9BX66
TCFPRKRISSKSLKV

SUGP2

946

Q8IX01
KSRKESTEPKTCIES

ZNF654

916

Q8IZM8
IKEKDRCPLSSSSLE

TTC14

571

Q96N46
DPKLCTKSPRKRLSS

RFX7

551

Q2KHR2
GVKISKARDKSPCRS

RGS14

446

O43566
SEISDSCKPLKKRSR

NSD3

621

Q9BZ95
SCKPLKKRSRASTDV

NSD3

626

Q9BZ95
LDCKQKKSRSRSGSK

ZNF644

1231

Q9H582
KKKPRTSFTRLQICE

TLX1

201

P31314
PRKKSDVTSILSECS

SCN11A

981

Q9UI33
SCKAPKVVRKADRSR

TMIGD3

196

P0DMS9
IDRKRLKKDVEPSCS

THAP4

256

Q8WY91
SSKPCRKVRETLAAE

LMX1B

241

O60663
EVTSEPRCKKLKSTT

N4BP2L2

16

Q92802
SDCTATKVPKTERKK

MYO9A

1971

B2RTY4