Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucosamine-6-phosphate deaminase activity	GNPDA1 GNPDA2	2.34e-05	2	97	2	GO:0004342
GeneOntologyBiologicalProcess	regulation of organelle organization	CARMIL2 PPP1R9A DVL3 AMBRA1 MARCHF7 CLASP2 ATG2A ECT2 SHANK3 ASAP1 HNRNPU CCDC88C MET NRXN1 HECW2 FSHR PRICKLE2 SLC35F6 CCT8 CCR7 PROX1	8.71e-07	1342	97	21	GO:0033043
GeneOntologyBiologicalProcess	guanylate kinase-associated protein clustering	SHANK3 NRXN1	2.19e-05	2	97	2	GO:0097117
GeneOntologyBiologicalProcess	glucosamine catabolic process	GNPDA1 GNPDA2	2.19e-05	2	97	2	GO:0006043
GeneOntologyBiologicalProcess	regulation of monoatomic ion transmembrane transporter activity	HECW1 SHANK3 CRHR1 ABCB1 JPH1 NRXN1 HECW2 MAPK8IP2	2.82e-05	256	97	8	GO:0032412
GeneOntologyBiologicalProcess	regulation of transmembrane transporter activity	HECW1 SHANK3 CRHR1 ABCB1 JPH1 NRXN1 HECW2 MAPK8IP2	3.70e-05	266	97	8	GO:0022898
GeneOntologyBiologicalProcess	cell morphogenesis	CNTN4 HECW1 PPP1R9A DVL3 CLASP2 SIPA1 ECT2 SHANK3 CCDC88C MET NRXN1 HECW2 MACF1 MUC3A ZMYM3 MAPK8IP2 PROX1	3.81e-05	1194	97	17	GO:0000902
GeneOntologyBiologicalProcess	regulation of actin filament-based process	CARMIL2 DSC2 PPP1R9A DVL3 CLASP2 ECT2 SHANK3 MET CCR7 PROX1	4.08e-05	438	97	10	GO:0032970
GeneOntologyBiologicalProcess	negative regulation of actin filament bundle assembly	PPP1R9A CLASP2 SHANK3 MET	5.91e-05	45	97	4	GO:0032232
GeneOntologyBiologicalProcess	N-acetylglucosamine catabolic process	GNPDA1 GNPDA2	6.55e-05	3	97	2	GO:0006046
GeneOntologyBiologicalProcess	organelle assembly	TRAF7 EQTN AMBRA1 MARCHF7 CLASP2 NUDCD3 ATG2A SHANK3 ASAP1 HNRNPU NRXN1 SPACA1 PRICKLE2 WDR90 FHDC1 PROX1	7.70e-05	1138	97	16	GO:0070925
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	CARMIL2 PPP1R9A DVL3 CLASP2 ECT2 SHANK3 MET CCR7 PROX1	8.26e-05	384	97	9	GO:0032956
GeneOntologyBiologicalProcess	regulation of transporter activity	HECW1 SHANK3 CRHR1 ABCB1 JPH1 NRXN1 HECW2 MAPK8IP2	8.40e-05	299	97	8	GO:0032409
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	CARMIL2 PPP1R9A DVL3 CLASP2 ECT2 SHANK3 HNRNPU CCDC88C MET CCR7 PROX1	8.69e-05	579	97	11	GO:0051493
GeneOntologyBiologicalProcess	actin filament-based process	CARMIL2 DSC2 PPP1R9A DVL3 CLASP2 ECT2 SHANK3 CCDC88C MET SCN9A ARHGAP25 CCR7 FHDC1 PROX1	9.07e-05	912	97	14	GO:0030029
GeneOntologyBiologicalProcess	cell cycle process	CDKN1C HUS1 RBL2 AMBRA1 MCM3 CLASP2 ECT2 FOXJ3 ESCO1 HNRNPU ABCB1 MET HECW2 TIPIN HFM1 KIF2C PROX1 NPAT	1.19e-04	1441	97	18	GO:0022402
GeneOntologyBiologicalProcess	negative regulation of organelle organization	CARMIL2 PPP1R9A MARCHF7 CLASP2 SHANK3 HNRNPU CCDC88C MET SLC35F6	1.65e-04	421	97	9	GO:0010639
GeneOntologyBiologicalProcess	mitotic cell cycle process	CDKN1C HUS1 RBL2 AMBRA1 MCM3 CLASP2 ECT2 HNRNPU ABCB1 MET HECW2 TIPIN KIF2C	1.79e-04	854	97	13	GO:1903047
GeneOntologyBiologicalProcess	regulation of cell projection organization	CARMIL2 HECW1 PPP1R9A DVL3 MARCHF7 SHANK3 ASAP1 MET NRXN1 HECW2 MACF1 CCR7 NDRG4	1.99e-04	863	97	13	GO:0031344
GeneOntologyBiologicalProcess	establishment or maintenance of cell polarity	CARMIL2 CLASP2 SIPA1 PRICKLE2 MACF1 CCR7 KIF2C	2.13e-04	257	97	7	GO:0007163
GeneOntologyBiologicalProcess	regulation of AMPA receptor activity	SHANK3 NRXN1 MAPK8IP2	2.15e-04	25	97	3	GO:2000311
GeneOntologyBiologicalProcess	regulation of actomyosin structure organization	PPP1R9A CLASP2 ECT2 MET PROX1	2.78e-04	122	97	5	GO:0110020
GeneOntologyBiologicalProcess	neuron projection development	CNTN4 HECW1 PPP1R9A DVL3 CLASP2 SHANK3 ASAP1 MET NRXN1 HECW2 FSHR PRICKLE2 MACF1 HERC1 NDRG4 MAPK8IP2	3.10e-04	1285	97	16	GO:0031175
GeneOntologyBiologicalProcess	negative regulation of cytoskeleton organization	CARMIL2 PPP1R9A CLASP2 SHANK3 CCDC88C MET	3.11e-04	194	97	6	GO:0051494
GeneOntologyBiologicalProcess	NMDA glutamate receptor clustering	SHANK3 NRXN1	3.24e-04	6	97	2	GO:0097114
GeneOntologyBiologicalProcess	regulation of grooming behavior	SHANK3 NRXN1	3.24e-04	6	97	2	GO:2000821
GeneOntologyBiologicalProcess	glucosamine metabolic process	GNPDA1 GNPDA2	3.24e-04	6	97	2	GO:0006041
GeneOntologyBiologicalProcess	negative regulation of supramolecular fiber organization	CARMIL2 PPP1R9A CLASP2 SHANK3 CCDC88C MET	3.38e-04	197	97	6	GO:1902904
GeneOntologyBiologicalProcess	dendrite morphogenesis	HECW1 PPP1R9A SHANK3 MET HECW2 MAPK8IP2	3.47e-04	198	97	6	GO:0048813
GeneOntologyBiologicalProcess	excitatory postsynaptic potential	PPP1R9A SHANK3 MET NRXN1 MAPK8IP2	3.73e-04	130	97	5	GO:0060079
GeneOntologyBiologicalProcess	chromosome organization	HUS1 MCM3 CLASP2 MSH3 ESCO1 HNRNPU HECW2 FSHR CCT8 HFM1 KIF2C	3.77e-04	686	97	11	GO:0051276
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	CARMIL2 PPP1R9A AMBRA1 MARCHF7 CLASP2 ATG2A ECT2 SHANK3 ASAP1 HNRNPU MET NRXN1 PRICKLE2 MACF1 CCR7	4.25e-04	1189	97	15	GO:0044087
GeneOntologyBiologicalProcess	neuron development	CDKN1C CNTN4 HECW1 PPP1R9A DVL3 CLASP2 SHANK3 ASAP1 MET NRXN1 HECW2 FSHR PRICKLE2 MACF1 HERC1 NDRG4 MAPK8IP2	4.40e-04	1463	97	17	GO:0048666
GeneOntologyBiologicalProcess	regulation of transmembrane transport	HECW1 RSC1A1 SHANK3 CRHR1 ABCB1 JPH1 MET NRXN1 HECW2 MAPK8IP2	4.52e-04	589	97	10	GO:0034762
GeneOntologyBiologicalProcess	vocal learning	SHANK3 NRXN1	4.53e-04	7	97	2	GO:0042297
GeneOntologyBiologicalProcess	N-acetylneuraminate catabolic process	GNPDA1 GNPDA2	4.53e-04	7	97	2	GO:0019262
GeneOntologyBiologicalProcess	imitative learning	SHANK3 NRXN1	4.53e-04	7	97	2	GO:0098596
GeneOntologyBiologicalProcess	cell differentiation in hindbrain	NRXN1 HERC1 PROX1	4.53e-04	32	97	3	GO:0021533
GeneOntologyBiologicalProcess	cell projection morphogenesis	CNTN4 HECW1 PPP1R9A DVL3 CLASP2 SHANK3 MET NRXN1 HECW2 MACF1 MUC3A MAPK8IP2	4.92e-04	826	97	12	GO:0048858
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	CARMIL2 PPP1R9A DVL3 ASAP1 MET NRXN1 MACF1 CCR7 NDRG4	5.33e-04	494	97	9	GO:0031346
GeneOntologyBiologicalProcess	postsynaptic density assembly	SHANK3 NRXN1 PRICKLE2	5.43e-04	34	97	3	GO:0097107
GeneOntologyBiologicalProcess	cerebellar cortex formation	NRXN1 HERC1 PROX1	5.43e-04	34	97	3	GO:0021697
GeneOntologyBiologicalProcess	neuronal signal transduction	NRXN1 MACO1	6.02e-04	8	97	2	GO:0023041
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	CARMIL2 HECW1 PPP1R9A MARCHF7 SHANK3 ASAP1 MET NRXN1 HECW2 MACF1 CCR7 NDRG4	6.08e-04	846	97	12	GO:0120035
GeneOntologyBiologicalProcess	chemical synaptic transmission, postsynaptic	PPP1R9A SHANK3 MET NRXN1 MAPK8IP2	6.54e-04	147	97	5	GO:0099565
GeneOntologyBiologicalProcess	actin filament organization	CARMIL2 PPP1R9A CLASP2 SHANK3 MET ARHGAP25 CCR7 FHDC1 PROX1	6.61e-04	509	97	9	GO:0007015
GeneOntologyBiologicalProcess	cell cycle phase transition	CDKN1C HUS1 RBL2 AMBRA1 CLASP2 ABCB1 HECW2 TIPIN PROX1 NPAT	7.33e-04	627	97	10	GO:0044770
GeneOntologyBiologicalProcess	glucosamine-containing compound catabolic process	GNPDA1 GNPDA2	7.71e-04	9	97	2	GO:1901072
GeneOntologyBiologicalProcess	UDP-N-acetylglucosamine biosynthetic process	GNPDA1 GNPDA2	7.71e-04	9	97	2	GO:0006048
GeneOntologyBiologicalProcess	observational learning	SHANK3 NRXN1	7.71e-04	9	97	2	GO:0098597
GeneOntologyBiologicalProcess	regulation of protein polymerization	CARMIL2 PPP1R9A AMBRA1 CLASP2 MET CCR7	7.82e-04	231	97	6	GO:0032271
GeneOntologyBiologicalProcess	negative regulation of stress fiber assembly	PPP1R9A CLASP2 MET	8.15e-04	39	97	3	GO:0051497
GeneOntologyBiologicalProcess	mitotic cell cycle	CDKN1C HUS1 RBL2 AMBRA1 MCM3 CLASP2 ECT2 HNRNPU ABCB1 MET HECW2 TIPIN KIF2C	9.15e-04	1014	97	13	GO:0000278
GeneOntologyBiologicalProcess	actomyosin structure organization	PPP1R9A CLASP2 ECT2 MET FHDC1 PROX1	9.33e-04	239	97	6	GO:0031032
GeneOntologyBiologicalProcess	positive regulation of extracellular matrix disassembly	CARMIL2 CLASP2	9.61e-04	10	97	2	GO:0090091
GeneOntologyBiologicalProcess	protein polymerization	CARMIL2 PPP1R9A AMBRA1 CLASP2 MET CCR7 FHDC1	1.01e-03	334	97	7	GO:0051258
GeneOntologyBiologicalProcess	dendrite development	HECW1 PPP1R9A SHANK3 ASAP1 MET HECW2 MAPK8IP2	1.03e-03	335	97	7	GO:0016358
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	DIABLO DVL3 MSH3 ECT2 CRHR1 ASAP1 HNRNPU MET NRXN1 FSHR ARHGAP25 CCR7 PROX1	1.04e-03	1028	97	13	GO:0043085
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	CARMIL2 PPP1R9A CLASP2 SHANK3 CCDC88C MET CCR7 PROX1	1.08e-03	438	97	8	GO:1902903
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection assembly	CARMIL2 PPP1R9A MARCHF7 ASAP1 NRXN1 CCR7	1.13e-03	248	97	6	GO:0120032
GeneOntologyBiologicalProcess	postsynaptic specialization assembly	SHANK3 NRXN1 PRICKLE2	1.16e-03	44	97	3	GO:0098698
GeneOntologyBiologicalProcess	amino sugar biosynthetic process	GNPDA1 GNPDA2	1.17e-03	11	97	2	GO:0046349
GeneOntologyBiologicalProcess	cerebellar granule cell differentiation	NRXN1 PROX1	1.17e-03	11	97	2	GO:0021707
GeneOntologyBiologicalProcess	cerebellar granular layer formation	NRXN1 PROX1	1.17e-03	11	97	2	GO:0021684
GeneOntologyBiologicalProcess	learned vocalization behavior or vocal learning	SHANK3 NRXN1	1.17e-03	11	97	2	GO:0098598
GeneOntologyBiologicalProcess	regulation of cell projection assembly	CARMIL2 PPP1R9A MARCHF7 ASAP1 NRXN1 CCR7	1.20e-03	251	97	6	GO:0060491
GeneOntologyBiologicalProcess	Golgi to plasma membrane protein transport	RSC1A1 ASAP1 MACF1	1.24e-03	45	97	3	GO:0043001
GeneOntologyBiologicalProcess	epithelium development	CDKN1C CARMIL2 DVL3 AMBRA1 CLASP2 SIPA1 SHANK3 CRHR1 ABCB1 TGFB1I1 CCDC88C MET FSHR KRT25 NDRG4 PROX1	1.31e-03	1469	97	16	GO:0060429
GeneOntologyBiologicalProcess	excitatory synapse assembly	SHANK3 NRXN1 PRICKLE2	1.32e-03	46	97	3	GO:1904861
GeneOntologyBiologicalProcess	neuron projection morphogenesis	CNTN4 HECW1 PPP1R9A DVL3 CLASP2 SHANK3 MET NRXN1 HECW2 MACF1 MAPK8IP2	1.36e-03	802	97	11	GO:0048812
GeneOntologyBiologicalProcess	positive regulation of protein polymerization	CARMIL2 AMBRA1 MET CCR7	1.37e-03	102	97	4	GO:0032273
GeneOntologyBiologicalProcess	actin cytoskeleton organization	CARMIL2 PPP1R9A DVL3 CLASP2 ECT2 SHANK3 MET ARHGAP25 CCR7 FHDC1 PROX1	1.37e-03	803	97	11	GO:0030036
Domain	HECW_N	HECW1 HECW2	2.56e-05	2	95	2	IPR032348
Domain	Glucosamine6P_isomerase_CS	GNPDA1 GNPDA2	2.56e-05	2	95	2	IPR018321
Domain	Glucosamine6P_isomerase	GNPDA1 GNPDA2	2.56e-05	2	95	2	IPR004547
Domain	GLC_GALNAC_ISOMERASE	GNPDA1 GNPDA2	2.56e-05	2	95	2	PS01161
Domain	HECW_N	HECW1 HECW2	2.56e-05	2	95	2	PF16562
Domain	Glc/Gal-6P_isomerase	GNPDA1 GNPDA2	1.53e-04	4	95	2	IPR006148
Domain	Glucosamine_iso	GNPDA1 GNPDA2	1.53e-04	4	95	2	PF01182
Domain	WD40_repeat_CS	TRAF7 COP1 AMBRA1 NWD2 WDR90 HERC1	1.91e-04	164	95	6	IPR019775
Domain	-	TRAF7 COP1 AMBRA1 MET NWD2 WDR90 HERC1 WDR13	2.97e-04	333	95	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	TRAF7 COP1 AMBRA1 MET NWD2 WDR90 HERC1 WDR13	3.09e-04	335	95	8	IPR015943
Domain	HECT	HECW1 HECW2 HERC1	3.41e-04	27	95	3	PF00632
Domain	HECTc	HECW1 HECW2 HERC1	3.41e-04	27	95	3	SM00119
Domain	HECT_dom	HECW1 HECW2 HERC1	3.41e-04	27	95	3	IPR000569
Domain	HECT	HECW1 HECW2 HERC1	3.41e-04	27	95	3	PS50237
Domain	WD40	TRAF7 COP1 AMBRA1 NWD2 WDR90 HERC1 WDR13	4.37e-04	268	95	7	SM00320
Domain	WD40_repeat	TRAF7 COP1 AMBRA1 NWD2 WDR90 HERC1 WDR13	4.77e-04	272	95	7	IPR001680
Domain	WD_REPEATS_1	TRAF7 COP1 AMBRA1 NWD2 WDR90 HERC1 WDR13	5.43e-04	278	95	7	PS00678
Domain	WD_REPEATS_2	TRAF7 COP1 AMBRA1 NWD2 WDR90 HERC1 WDR13	5.55e-04	279	95	7	PS50082
Domain	WD_REPEATS_REGION	TRAF7 COP1 AMBRA1 NWD2 WDR90 HERC1 WDR13	5.55e-04	279	95	7	PS50294
Domain	PDZ	PPP1R9A DVL3 SIPA1 SHANK3 LMO7	7.68e-04	141	95	5	PF00595
Domain	WD40_repeat_dom	TRAF7 COP1 AMBRA1 NWD2 WDR90 HERC1 WDR13	8.02e-04	297	95	7	IPR017986
Domain	LAM_G_DOMAIN	CNTNAP3B CNTNAP3 NRXN1	9.45e-04	38	95	3	PS50025
Domain	PDZ	PPP1R9A DVL3 SIPA1 SHANK3 LMO7	9.54e-04	148	95	5	SM00228
Domain	-	PPP1R9A DVL3 SIPA1 SHANK3 LMO7	1.01e-03	150	95	5	2.30.42.10
Domain	PDZ	PPP1R9A DVL3 SIPA1 SHANK3 LMO7	1.04e-03	151	95	5	PS50106
Domain	PDZ	PPP1R9A DVL3 SIPA1 SHANK3 LMO7	1.08e-03	152	95	5	IPR001478
Domain	Laminin_G_2	CNTNAP3B CNTNAP3 NRXN1	1.10e-03	40	95	3	PF02210
Domain	LRR_5	TLR7 FSHR	1.12e-03	10	95	2	PF13306
Domain	LRR_5	TLR7 FSHR	1.12e-03	10	95	2	IPR026906
Domain	LamG	CNTNAP3B CNTNAP3 NRXN1	1.45e-03	44	95	3	SM00282
Domain	HEAT	CAND2 CLASP2 MROH1	1.87e-03	48	95	3	PF02985
Domain	WD40	TRAF7 COP1 AMBRA1 WDR90 HERC1 WDR13	2.08e-03	259	95	6	PF00400
Domain	SEA	MUC16 MUC3A	2.24e-03	14	95	2	SM00200
Domain	Laminin_G	CNTNAP3B CNTNAP3 NRXN1	3.21e-03	58	95	3	IPR001791
Domain	HEAT	CAND2 CLASP2 MROH1	3.21e-03	58	95	3	IPR000357
Domain	C2	HECW1 HECW2 RIMS4 SYTL1	4.50e-03	131	95	4	PF00168
Domain	FA58C	CNTNAP3B CNTNAP3	5.05e-03	21	95	2	SM00231
Domain	FA58C_3	CNTNAP3B CNTNAP3	5.05e-03	21	95	2	PS50022
Domain	FA58C_1	CNTNAP3B CNTNAP3	5.05e-03	21	95	2	PS01285
Domain	FA58C_2	CNTNAP3B CNTNAP3	5.05e-03	21	95	2	PS01286
Domain	ConA-like_dom	CNTNAP3B CNTNAP3 HNRNPU NRXN1 HERC1	5.22e-03	219	95	5	IPR013320
Domain	LIM	TGFB1I1 LMO7 PRICKLE2	5.24e-03	69	95	3	PF00412
Domain	C2	HECW1 HECW2 RIMS4 SYTL1	5.27e-03	137	95	4	SM00239
Domain	-	TGFB1I1 LMO7 PRICKLE2	5.46e-03	70	95	3	2.10.110.10
Domain	HEAT_REPEAT	CAND2 CLASP2 MROH1	5.46e-03	70	95	3	PS50077
Domain	Znf_LIM	TGFB1I1 LMO7 PRICKLE2	5.68e-03	71	95	3	IPR001781
Domain	LIM_DOMAIN_1	TGFB1I1 LMO7 PRICKLE2	5.68e-03	71	95	3	PS00478
Domain	LIM_DOMAIN_2	TGFB1I1 LMO7 PRICKLE2	5.68e-03	71	95	3	PS50023
Domain	LIM	TGFB1I1 LMO7 PRICKLE2	5.68e-03	71	95	3	SM00132
Domain	C2	HECW1 HECW2 RIMS4 SYTL1	5.98e-03	142	95	4	PS50004
Domain	SEA	MUC16 MUC3A	6.04e-03	23	95	2	PS50024
Domain	SEA_dom	MUC16 MUC3A	6.04e-03	23	95	2	IPR000082
Domain	F5_F8_type_C	CNTNAP3B CNTNAP3	6.57e-03	24	95	2	PF00754
Domain	FA58C	CNTNAP3B CNTNAP3	6.57e-03	24	95	2	IPR000421
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CNTN4 HECW1 PPP1R9A MCM3 CLASP2 ZNF318 SIPA1 SHANK3 HNRNPU CCDC88C NRXN1 CCT8 MACF1 MAPK8IP2 KIF2C PROX1	1.20e-08	963	98	16	28671696
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CNTN4 GNPDA1 HECW1 ATP8B2 ESCO1 SHANK3 CCDC88C TRIM66 CCT8 MACF1 ARHGAP25 FHDC1	1.55e-08	493	98	12	15368895
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CARMIL2 PPP1R9A KLC2 PSMD2 CLASP2 SIPA1 NDUFA9 SHANK3 ASAP1 HNRNPU NWD2 LMO7 HECW2 PRICKLE2 CCT8 MACF1 MAPK8IP2	4.92e-07	1431	98	17	37142655
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	HECW1 BAG2 DVL3 KLC2 PSMD2 NDUFA9 SHANK3 ASAP1 HNRNPU MET NRXN1 PRICKLE2 CCT8 MACF1 NDRG4	7.02e-07	1139	98	15	36417873
Pubmed	EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.	CLASP2 MACF1 KIF2C	2.57e-06	10	98	3	23001180
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CAND2 AKNA AMBRA1 NUDCD3 ATG2A FOXJ3 LMO7 HECW2 WDR90 NDRG4	2.58e-06	529	98	10	14621295
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	BAG2 MCM3 PSMD2 ZNF318 HNRNPU CCT8	5.54e-06	156	98	6	32850835
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TRAF7 KLC2 MCM3 ZNF318 NUDCD3 LMO7 MACO1 MACF1 ZMYM3 KIF2C	6.53e-06	588	98	10	38580884
Pubmed	Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.	GNPDA1 GNPDA2	7.86e-06	2	98	2	12965206
Pubmed	Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.	GNPDA1 GNPDA2	7.86e-06	2	98	2	12616532
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	7.86e-06	2	98	2	26807827
Pubmed	Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.	ABCB1 MET	7.86e-06	2	98	2	26351321
Pubmed	A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.	ASAP1 PROX1	7.86e-06	2	98	2	25879659
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	7.86e-06	2	98	2	31150793
Pubmed	Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion.	SHANK3 MAPK8IP2	7.86e-06	2	98	2	23225497
Pubmed	Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.	SLC46A1 ABCB1	7.86e-06	2	98	2	23212123
Pubmed	Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines.	ABCB1 MET	7.86e-06	2	98	2	25908454
Pubmed	The phytochrome A-specific signaling intermediate SPA1 interacts directly with COP1, a constitutive repressor of light signaling in Arabidopsis.	COP1 SIPA1	7.86e-06	2	98	2	11461903
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	PPP1R9A MSH3 SIPA1 HNRNPU MET LMO7 MACF1 PROX1	8.54e-06	360	98	8	33111431
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	CNTNAP3B BAG2 CNTNAP3 SLC46A1 CLASP2 ATP8B2 MET MROH1 LMO7 MACO1 SLC35F6 MACF1 HERC1	9.00e-06	1061	98	13	33845483
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	BAG2 AMBRA1 MCM3 MARCHF7 PSMD2 CLASP2 ZNF318 HNRNPU LMO7 CCT8	1.09e-05	624	98	10	33729478
Pubmed	MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.	MCM3 PSMD2 NDUFA9 HNRNPU MET CCT8	1.34e-05	182	98	6	30711629
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TRAF7 DSC2 BAG2 AMBRA1 ZNF318 SIPA1 JPH1 TRIM66 MACF1 WDR13 TLCD3A ZMYM3 PROX1	1.54e-05	1116	98	13	31753913
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	GNPDA1 PSMD2 MET LMO7 CCT8 MACF1	1.76e-05	191	98	6	33762435
Pubmed	AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics.	BAG2 AMBRA1 PSMD2 CCT8	2.24e-05	58	98	4	25499913
Pubmed	The clinical significance of the combined detection of serum Smac, HE4 and CA125 in endometriosis-associated ovarian cancer.	DIABLO MUC16	2.35e-05	3	98	2	29226858
Pubmed	Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models.	CNTN4 SHANK3	2.35e-05	3	98	2	29970989
Pubmed	STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57Kip2.	CDKN1C COP1	2.35e-05	3	98	2	39304928
Pubmed	Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma.	PPP1R9A ABCB1	2.35e-05	3	98	2	25057852
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	BAG2 AMBRA1 MCM3 PSMD2 MSH3 NDUFA9 ECT2 ASAP1 HNRNPU CCT8 MACF1 WDR13 ZMYM3 KIF2C	2.62e-05	1353	98	14	29467282
Pubmed	A cohesin-RAD21 interactome.	MCM3 PSMD2 CLASP2 HNRNPU CCT8 NPAT	2.84e-05	208	98	6	22145905
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	CAND2 DSC2 KLC2 ATP8B2 ESCO1 TGFB1I1 TRIM66 SLC41A3 HECW2 SLC35F6 ARHGAP25 HERC1 SYTL1	4.65e-05	1242	98	13	30973865
Pubmed	CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature.	CCR7 PROX1	4.70e-05	4	98	2	30224810
Pubmed	CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P.	CDKN1C NPAT	4.70e-05	4	98	2	19170105
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	AKNA SHANK3 MACO1 SCN9A PRICKLE2 MAPK8IP2	5.34e-05	233	98	6	37704626
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	HECW1 HECW2 HERC1	5.38e-05	26	98	3	26949039
Pubmed	Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.	CLASP2 MACF1	7.82e-05	5	98	2	17113391
Pubmed	CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability.	CCR7 PROX1	7.82e-05	5	98	2	26999610
Pubmed	NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.	HECW1 HECW2	7.82e-05	5	98	2	14684739
Pubmed	Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.	ABCB1 ABCB9	7.82e-05	5	98	2	11829140
Pubmed	Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells.	CLASP2 PRICKLE2	7.82e-05	5	98	2	27378169
Pubmed	Defect of LSS Disrupts Lens Development in Cataractogenesis.	CDKN1C PROX1	7.82e-05	5	98	2	34926465
Pubmed	Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.	GNPDA1 GNPDA2	7.82e-05	5	98	2	26887390
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CAND2 DIABLO DVL3 AMBRA1 MCM3 CLASP2 NDUFA9 MFSD4B ECT2 NRXN1 LMO7 SLC35F6 KIF2C	8.66e-05	1321	98	13	27173435
Pubmed	Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation.	CNTN4 SHANK3 NRXN1	9.21e-05	31	98	3	19736351
Pubmed	HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.	MCM3 LMO7 KIF2C	1.01e-04	32	98	3	27114546
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CLASP2 NWD2 ABCB9 NRXN1	1.10e-04	87	98	4	12465718
Pubmed	An EB1-binding motif acts as a microtubule tip localization signal.	CLASP2 KIF2C	1.17e-04	6	98	2	19632184
Pubmed	Hepatocyte migration during liver development requires Prox1.	MET PROX1	1.17e-04	6	98	2	10888866
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3	1.17e-04	6	98	2	34143959
Pubmed	Proteolytic targeting of transcriptional regulator TIP120B by a HECT domain E3 ligase.	CAND2 PSMD2	1.17e-04	6	98	2	12692129
Pubmed	A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle.	CDKN1C PROX1	1.17e-04	6	98	2	10652278
Pubmed	Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses.	TLR7 CCR7	1.17e-04	6	98	2	19710454
Pubmed	Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1.	HUS1 MSH3	1.17e-04	6	98	2	20188637
Pubmed	Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.	NRXN1 SYTL1	1.17e-04	6	98	2	11243866
Pubmed	Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.	PSMD2 CLASP2 HNRNPU CCDC88C CCT8	1.31e-04	172	98	5	23184937
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	BAG2 MCM3 PSMD2 HNRNPU CCT8	1.42e-04	175	98	5	25756610
Pubmed	Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.	HUS1 RBL2 MCM3 TGFB1I1 MACF1	1.49e-04	177	98	5	22560297
Pubmed	Dissociation of heterotrimeric g proteins in cells.	CRHR1 P2RY4 FSHR CCR7 S1PR4	1.57e-04	179	98	5	18577758
Pubmed	ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.	CLASP2 MACF1	1.64e-04	7	98	2	20937854
Pubmed	Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry.	RBL2 NPAT	1.64e-04	7	98	2	9472014
Pubmed	The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes.	CDKN1C RBL2	1.64e-04	7	98	2	15124025
Pubmed	Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice.	CDKN1C PROX1	1.64e-04	7	98	2	16199865
Pubmed	Expression of P2Y(6) receptors in the developing mouse skeletal muscle and after injury and repair.	MET P2RY4	1.64e-04	7	98	2	21413988
Pubmed	Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.	CRHR1 ABCB1	1.64e-04	7	98	2	19844206
Pubmed	Planar cell polarity induces local microtubule bundling for coordinated ciliary beating.	CCDC88C PRICKLE2	1.64e-04	7	98	2	33929515
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	AMBRA1 MCM3 PSMD2 CLASP2 HNRNPU CCDC88C CCT8 KIF2C	1.70e-04	551	98	8	34728620
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	BAG2 MCM3 PSMD2 SIPA1 NDUFA9 HNRNPU CCT8 MACF1 KIF2C	1.77e-04	707	98	9	19738201
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DSC2 BAG2 MCM3 PSMD2 HNRNPU JPH1 CCT8 MACF1 KIF2C	1.79e-04	708	98	9	39231216
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	CLASP2 NDUFA9 MET RIN2 GNPDA2	1.88e-04	186	98	5	33637726
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PPP1R9A ASAP1 NWD2 MACF1	2.12e-04	103	98	4	10574462
Pubmed	FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.	ABCB1 CCR7	2.18e-04	8	98	2	15240672
Pubmed	Prox1 regulates a transitory state for interneuron neurogenesis in the spinal cord.	CDKN1C PROX1	2.18e-04	8	98	2	18213584
Pubmed	A HECT domain E3 enzyme assembles novel polyubiquitin chains.	CAND2 PSMD2	2.18e-04	8	98	2	11278995
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CAND2 BAG2 MCM3 PSMD2 ABCB1 HECW2	2.66e-04	313	98	6	38270169
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	PPP1R9A BAG2 KLC2 CLASP2 CCDC88C LMO7 KIF2C	2.76e-04	446	98	7	24255178
Pubmed	JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development.	CDKN1C PROX1	2.79e-04	9	98	2	38095908
Pubmed	Expression of planar cell polarity genes during development of the mouse CNS.	DVL3 PRICKLE2	2.79e-04	9	98	2	16487141
Pubmed	The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.	CDKN1C PROX1	2.79e-04	9	98	2	21504908
Pubmed	Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.	SHANK3 NRXN1	2.79e-04	9	98	2	23010509
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PPP1R9A CLASP2 NUDCD3 FOXJ3 PLBD2 ESCO1 HNRNPU SLC41A3 RIN2 MACF1 SYTL1 WDR13 KLHL26	2.81e-04	1489	98	13	28611215
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	MCM3 PSMD2 SIPA1 HNRNPU CCT8 MACF1	3.36e-04	327	98	6	31409639
Pubmed	Perturbed hematopoiesis in mice lacking ATMIN.	CDKN1C RBL2	3.48e-04	10	98	2	27581360
Pubmed	Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia.	CDKN1C PROX1	3.48e-04	10	98	2	18652815
Pubmed	ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.	CLASP2 MACF1	3.48e-04	10	98	2	18854161
Pubmed	Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells.	CDKN1C PROX1	3.48e-04	10	98	2	19007884
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	PPP1R9A BAG2 MCM3 PSMD2 ECT2 HNRNPU JPH1 LMO7 CCT8 KIF2C	3.50e-04	949	98	10	36574265
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	MCM3 MSH3 HNRNPU LMO7 ZMYM3 KIF2C	3.64e-04	332	98	6	32786267
Pubmed	AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.	TRAF7 SLC46A1 SHANK3 TLCD3A	3.91e-04	121	98	4	31900314
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	BAG2 MCM3 PSMD2 NDUFA9 SHANK3 HNRNPU LMO7 PROX1	4.01e-04	626	98	8	33644029
Pubmed	Znhit1 Regulates p21Cip1 to Control Mouse Lens Differentiation.	CDKN1C PROX1	4.25e-04	11	98	2	35472217
Pubmed	NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.	HECW1 HECW2	4.25e-04	11	98	2	25555806
Pubmed	Role of cell and matrix-bound VEGF isoforms in lens development.	CDKN1C PROX1	4.25e-04	11	98	2	18757513
Pubmed	The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.	CDKN1C PROX1	4.25e-04	11	98	2	20181838
Pubmed	Differential requirement for beta-catenin in epithelial and fiber cells during lens development.	CDKN1C PROX1	4.25e-04	11	98	2	18652817
Pubmed	Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting Complex.	MCM3 ESCO1	4.25e-04	11	98	2	30100344
Pubmed	Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.	SHANK3 MACF1	4.25e-04	11	98	2	39256359
Pubmed	Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice.	CDKN1C PROX1	4.25e-04	11	98	2	16446698
Pubmed	Behavioral phenotypes of genetic mouse models of autism.	SHANK3 NRXN1	4.25e-04	11	98	2	26403076
Pubmed	Activation of the hedgehog signaling pathway in the developing lens stimulates ectopic FoxE3 expression and disruption in fiber cell differentiation.	CDKN1C PROX1	4.25e-04	11	98	2	22491411
Interaction	DVL1 interactions	HECW1 DVL3 COP1 SIPA1 SHANK3 CCDC88C NRXN1 PRICKLE2	5.78e-07	151	95	8	int:DVL1
Interaction	CCNA1 interactions	RBL2 PROCA1 TGFB1I1 HECW2 NPAT	1.19e-05	63	95	5	int:CCNA1
Cytoband	7p13-p12	HUS1 NUDCD3	9.41e-05	7	98	2	7p13-p12
GeneFamily	PDZ domain containing	PPP1R9A DVL3 SIPA1 SHANK3 LMO7	2.33e-04	152	66	5	1220
GeneFamily	WD repeat domain containing	TRAF7 COP1 AMBRA1 WDR90 HERC1 WDR13	3.84e-04	262	66	6	362
GeneFamily	ATP binding cassette subfamily B	ABCB1 ABCB9	7.07e-04	11	66	2	806
GeneFamily	LIM domain containing	TGFB1I1 LMO7 PRICKLE2	1.31e-03	59	66	3	1218
GeneFamily	CD molecules\|Mucins	MUC16 MUC3A	2.64e-03	21	66	2	648
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#3_top-relative-expression-ranked_500	CNTN4 ZNF318 ESCO1 TRIM66 SPACA1 HERC1	1.40e-05	113	98	6	gudmap_developingGonad_e16.5_ovary_500_k3
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_500	CNTN4 ZNF318 ESCO1 TRIM66 SPACA1 HERC1	3.69e-05	134	98	6	gudmap_developingGonad_e18.5_ovary_500_k1
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_500	CNTN4 ZNF318 ECT2 SPACA1 HERC1	6.42e-05	91	98	5	gudmap_developingGonad_e14.5_ ovary_500_k5
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000	CNTN4 ZNF318 ESCO1 ABCB1 TRIM66 SPACA1 HERC1	9.57e-05	230	98	7	gudmap_developingGonad_e18.5_ovary_1000_k5
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CNTNAP3 SHANK3 ASAP1 SCN9A FRG2C PROX1	1.66e-07	183	98	7	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B SLC26A4 CNTNAP3 ASAP1 SCN9A FRG2C PROX1	1.86e-07	186	98	7	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B SHANK3 ASAP1 HECW2 SCN9A MACF1 PROX1	1.86e-07	186	98	7	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 ABCB1 RIN2 NDRG4	1.90e-06	167	98	6	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B SHANK3 ASAP1 SCN9A MACF1 PROX1	2.74e-06	178	98	6	ad3de3e03a401dac64431a541899445262246347
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 ABCB1 RIN2 NDRG4	2.93e-06	180	98	6	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SHANK3 ASAP1 HECW2 SCN9A MACF1 PROX1	3.02e-06	181	98	6	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B SLC26A4 CNTNAP3 ASAP1 SCN9A PROX1	3.12e-06	182	98	6	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PROCA1 ECT2 RIN2 HFM1 TLCD3A KIF2C	3.22e-06	183	98	6	f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B PPP1R9A CNTNAP3 SHANK3 CCDC88C S1PR4	3.32e-06	184	98	6	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 PPP1R9A JPH1 MET LMO7 PRICKLE2	3.43e-06	185	98	6	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AKNA CCDC88C ARHGAP25 CCR7 PZP S1PR4	3.54e-06	186	98	6	9d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RBL2 AKNA CCDC88C ARHGAP25 CCR7 S1PR4	3.54e-06	186	98	6	bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RBL2 AKNA CCDC88C ARHGAP25 CCR7 S1PR4	3.54e-06	186	98	6	924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 ABCB1 RIN2 NDRG4	3.65e-06	187	98	6	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHANK3 ABCB1 HECW2 SCN9A PRICKLE2 NDRG4	3.88e-06	189	98	6	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 CNTNAP3B HECW1 PPP1R9A ABCB1 MET	3.88e-06	189	98	6	28b502611829e4a24caff2562545c7db97686099
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CARMIL2 HECW1 TRIM66 RIMS4 NDRG4 MAPK8IP2	4.00e-06	190	98	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	4.12e-06	191	98	6	1de0bdfd13bd930691564c2673f2e66393bc0255
ToppCell	(210)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	RBL2 AKNA ABCB1 CCDC88C MACF1 SYTL1	4.24e-06	192	98	6	08dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell	(21)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	RBL2 AKNA ABCB1 CCDC88C MACF1 SYTL1	4.24e-06	192	98	6	b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPP1R9A SHANK3 ABCB1 HECW2 SCN9A PRICKLE2	4.37e-06	193	98	6	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPP1R9A SHANK3 ABCB1 HECW2 SCN9A PRICKLE2	4.37e-06	193	98	6	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	CARMIL2 HECW1 TRIM66 RIMS4 NDRG4 MAPK8IP2	4.37e-06	193	98	6	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	Children_(3_yrs)-Endothelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B SHANK3 HECW2 PRICKLE2 NDRG4 PROX1	4.64e-06	195	98	6	094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	RBL2 AKNA ATP8B2 CCDC88C MACF1 ARHGAP25	4.78e-06	196	98	6	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	nucseq-Endothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CNTNAP3B SHANK3 HECW2 PRICKLE2 NDRG4 PROX1	4.92e-06	197	98	6	ebf9be068eaa658493fa7884fd19f34642922acb
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B CNTNAP3 SHANK3 ASAP1 HECW2 PROX1	5.06e-06	198	98	6	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B CNTNAP3 SHANK3 ASAP1 HECW2 PROX1	5.06e-06	198	98	6	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	Bronchial-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B SHANK3 ASAP1 HECW2 NDRG4 PROX1	5.21e-06	199	98	6	36a230b80096455df26c2e2c8c05fd6b231508c5
ToppCell	Parenchymal-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B SHANK3 ASAP1 HECW2 NDRG4 PROX1	5.21e-06	199	98	6	a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCell	healthy_donor-Lymphocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	RBL2 AKNA ATP8B2 CCDC88C MACF1 ARHGAP25	5.21e-06	199	98	6	2841e16d54acd344ba454f024e285c28abc37319
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T\|COVID-19_Mild / Disease, condition lineage and cell class	AKNA ATG2A ABCB1 CCDC88C MACF1 PZP	5.36e-06	200	98	6	6560753d3df2f87860b52052d4881aa45410f666
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CNTNAP3B SLC26A4 SHANK3 HECW2 SCN9A PROX1	5.36e-06	200	98	6	f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CNTNAP3B SLC26A4 SHANK3 HECW2 SCN9A PROX1	5.36e-06	200	98	6	e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Lymphatic\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CNTNAP3B SLC26A4 SHANK3 HECW2 SCN9A PROX1	5.36e-06	200	98	6	4ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCell	healthy_donor\|World / Disease condition, Lineage, Cell class and subclass	AKNA ABCB1 CCDC88C MACF1 ARHGAP25 SYTL1	5.36e-06	200	98	6	afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRAF7 CNTNAP3B CNTNAP3 SHANK3 ABCB1	1.67e-05	144	98	5	748f4efc59f7afbce6c497524f36d852b8b1d637
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	CNTN4 HECW1 ASAP1 MET NWD2	2.70e-05	159	98	5	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	CNTN4 TLR7 ARHGAP25 CCR7 PZP	3.41e-05	167	98	5	d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 TLR7 MET LMO7 PRICKLE2	3.71e-05	170	98	5	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	4.03e-05	173	98	5	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AKNA CCDC88C MACF1 PZP S1PR4	4.03e-05	173	98	5	36a471576a9d2325066bb14c2f2cd89c67b92915
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	AMBRA1 MFSD4B TGFB1I1 CCR7 WDR13	4.26e-05	175	98	5	da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell	Control-Neuronal_cells-Neuronal_cells\|Control / group, cell type (main and fine annotations)	CNTNAP3B SHANK3 ASAP1 HECW2 PROX1	4.38e-05	176	98	5	98c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell	Control-Neuronal_cells\|Control / group, cell type (main and fine annotations)	CNTNAP3B SHANK3 ASAP1 HECW2 PROX1	4.38e-05	176	98	5	c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A4 CNTNAP3 ASAP1 HECW2 SCN9A	4.50e-05	177	98	5	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A4 CNTNAP3 ASAP1 HECW2 SCN9A	4.50e-05	177	98	5	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A4 CNTNAP3 ASAP1 HECW2 SCN9A	4.50e-05	177	98	5	c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 MET NRXN1 PRICKLE2 SYTL1	4.62e-05	178	98	5	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B CNTNAP3 SHANK3 CCDC88C S1PR4	4.62e-05	178	98	5	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 PPP1R9A JPH1 MET LMO7	4.75e-05	179	98	5	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CDKN1C CNTN4 PPP1R9A MET LMO7	4.75e-05	179	98	5	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 SLC26A4 NRXN1 MAPK8IP2 PROX1	4.87e-05	180	98	5	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	4.87e-05	180	98	5	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	COPD-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	5.00e-05	181	98	5	61608123959483ff60f07d8467996853c4371b6a
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B2 SHANK3 ASAP1 HECW2 PRICKLE2	5.00e-05	181	98	5	4df7972f88117108698efd06b124b232f8588981
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B2 SHANK3 ASAP1 HECW2 PRICKLE2	5.00e-05	181	98	5	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ATG2A RSC1A1 MACO1 FHDC1 HERC1	5.13e-05	182	98	5	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC26A4 CNTNAP3 ASAP1 HECW2 PROX1	5.13e-05	182	98	5	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	facs-Heart-LV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG2A SIPA1 CCDC88C ARHGAP25 CCR7	5.13e-05	182	98	5	6dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	5.13e-05	182	98	5	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SLC26A4 CNTNAP3 AKNA SCN9A	5.27e-05	183	98	5	5a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC26A4 CNTNAP3 ASAP1 HECW2 PROX1	5.41e-05	184	98	5	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	COPD-Endothelial-VE_Capillary_A\|COPD / Disease state, Lineage and Cell class	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	5.41e-05	184	98	5	5f4f7775d488ececf086c71441defecbee9d8a9c
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	CNTN4 SLC26A4 PPP1R9A MET LMO7	5.55e-05	185	98	5	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	CNTNAP3B SHANK3 HECW2 SCN9A PROX1	5.55e-05	185	98	5	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	PCW_05-06-Neuronal-Neuronal_postreplicative\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ABCB1 NRXN1 SCN9A NDRG4 MAPK8IP2	5.55e-05	185	98	5	512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	AKNA ABCB1 CCDC88C ARHGAP25 PZP	5.55e-05	185	98	5	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SLC26A4 CNTNAP3 AKNA SCN9A	5.55e-05	185	98	5	e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	CNTNAP3B SHANK3 HECW2 SCN9A PROX1	5.55e-05	185	98	5	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	5.55e-05	185	98	5	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TRIM66 NWD2 SCN9A NDRG4 MAPK8IP2	5.69e-05	186	98	5	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF318 ESCO1 HNRNPU MACF1 CCR7	5.69e-05	186	98	5	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHANK3 ABCB1 HECW2 SCN9A PRICKLE2	5.84e-05	187	98	5	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	CNTNAP3B SHANK3 ABCB1 MET NDRG4	5.84e-05	187	98	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	5.84e-05	187	98	5	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	5.84e-05	187	98	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B SHANK3 ABCB1 HECW2 PRICKLE2	5.99e-05	188	98	5	117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	5.99e-05	188	98	5	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	5.99e-05	188	98	5	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	5.99e-05	188	98	5	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 NRXN1 MAPK8IP2 PROX1	5.99e-05	188	98	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	Control-Endothelial_cells\|Control / group, cell type (main and fine annotations)	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	5.99e-05	188	98	5	3953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	6.14e-05	189	98	5	0d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	6.14e-05	189	98	5	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 CNTNAP3B PPP1R9A ABCB1 MET	6.14e-05	189	98	5	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SLC26A4 CNTNAP3 AKNA SCN9A	6.14e-05	189	98	5	78cf414b98bcb19deb934409acddaad1cd51b67f
ToppCell	ASK452-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	MUC16 FOXJ3 SHANK3 ABCB1 HERC1	6.14e-05	189	98	5	f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	6.14e-05	189	98	5	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC26A4 CRHR1 SLC7A4 LMO7 PRICKLE2	6.14e-05	189	98	5	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SLC26A4 CNTNAP3 AKNA SCN9A	6.30e-05	190	98	5	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHANK3 ASAP1 HECW2 SCN9A PROX1	6.30e-05	190	98	5	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RBL2 ESCO1 MACF1 SYTL1 S1PR4	6.30e-05	190	98	5	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RBL2 ABCB1 CCDC88C CCR7 PZP	6.30e-05	190	98	5	2a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	6.30e-05	190	98	5	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	IPF-Endothelial-VE_Capillary_A\|IPF / Disease state, Lineage and Cell class	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	6.30e-05	190	98	5	b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	6.30e-05	190	98	5	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHANK3 HECW2 RIN2 PRICKLE2 NDRG4	6.30e-05	190	98	5	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 SHANK3 HECW2 PROX1	6.30e-05	190	98	5	91bf3b7e9148589757436a53a4f58e0ebfe54400
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3 SHANK3 MET NRXN1 RIMS4	8.38e-06	152	92	6	DOID:0060041 (implicated_via_orthology)
Disease	Pain, Postoperative	CRHR1 ABCB1	9.62e-06	2	92	2	C0030201
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	1.43e-04	6	92	2	EFO_0004307, EFO_0008463
Disease	triacylglycerol 58:10 measurement	CNTN4 NRXN1 SCN9A	1.64e-04	34	92	3	EFO_0010437
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	2.66e-04	8	92	2	DOID:0060308 (implicated_via_orthology)
Disease	gallbladder neoplasm	CNTN4 ABCB1	3.41e-04	9	92	2	EFO_0004606
Disease	Semantic-Pragmatic Disorder	SHANK3 NRXN1	5.19e-04	11	92	2	C0454655
Disease	Auditory Processing Disorder, Central	SHANK3 NRXN1	5.19e-04	11	92	2	C0751257
Disease	Language Delay	SHANK3 NRXN1	5.19e-04	11	92	2	C0023012
Disease	Language Development Disorders	SHANK3 NRXN1	5.19e-04	11	92	2	C0023014
Disease	Speech Delay	SHANK3 NRXN1	5.19e-04	11	92	2	C0241210
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MET MUC3A	1.06e-03	64	92	3	DOID:4947 (is_marker_for)
Disease	schizophrenia (implicated_via_orthology)	SHANK3 NRXN1 RIMS4	1.27e-03	68	92	3	DOID:5419 (implicated_via_orthology)
Disease	Autistic Disorder	CNTN4 COP1 SHANK3 MET NRXN1	1.37e-03	261	92	5	C0004352
Disease	Schizophrenia	SHANK3 NRXN1	1.42e-03	18	92	2	cv:C0036341
Disease	Osteoarthritis of hip	DIABLO CRHR1	1.76e-03	20	92	2	C0029410
Disease	Anhedonia	CRHR1 CCR7	2.54e-03	24	92	2	C0178417

Protein segments in the cluster

Peptide	Gene	Start	Entry
MSRISDDSRTASQLD	COP1	376	Q8NHY2
TLTREMITLSFRTTR	CNTNAP3	1036	Q9BZ76
MLARLERSSPSESTD	CARMIL2	136	Q6F5E8
IRRSSMSVEAETTTT	CCR7	361	P32248
SAISTIMISLTARSS	CNTN4	1011	Q8IWV2
DSTMETSLRRCLSTL	SLC7A4	26	O43246
EALMRRAVSLVTDST	DIABLO	71	Q9NR28
RTVLSLNSRSEAESM	AMBRA1	421	Q9C0C7
FSSSTEQSSASRLMR	DVL3	201	Q92997
TVRDRLGMSSVTSLD	DSC2	651	Q02487
SSVRSDMASRRLSAQ	ATG2A	391	Q2TAZ0
MRLSSLALSSFTTRS	ATP8B2	1166	P98198
RRSRSESETSTMAAK	C18orf25	141	Q96B23
VRFLGTTDMSSDLRT	NWD2	451	Q9ULI1
TTDMSSDLRTLLLSV	NWD2	456	Q9ULI1
TVKMLERSSSVSRTE	PZP	1401	P20742
TKDMDSTLSRASRAI	ECT2	816	Q9H8V3
LEMSSNDSRSSLIRK	ABCB1	651	P08183
MILSRAAISRTTSAT	NPAT	1336	Q14207
TSRDSSPVMRSSSTL	RBL2	961	Q08999
DLVTSESRSSLTASM	HECW2	51	Q9P2P5
ARNTVASSSRSMRTD	FHDC1	1036	Q9C0D6
MTLSNAETSAERVRS	MUC16	331	Q8WXI7
STNMALERRSSTATV	MUC16	1661	Q8WXI7
ARTESSSATLMSTAL	MUC16	1786	Q8WXI7
RISSSFLAQSMRSSD	MUC16	4056	Q8WXI7
MRSSDSPSEAITRLS	MUC16	4066	Q8WXI7
RISASSVLTESAKMT	MUC16	7606	Q8WXI7
QDSASRSELETRMSS	MSH3	406	P20585
IMETTTTLATSTARR	NRXN1	316	P58400
VSSSRSRTFRMALLE	SLC46A1	171	Q96NT5
SSLVSRTRVKTLAMD	GNPDA1	151	P46926
SVALSSSSIRVAMLE	NUDCD3	216	Q8IVD9
DLVTSDSRSTLMVSS	HECW1	71	Q76N89
RLRFTSKVSATDMST	KIAA1109	3026	Q2LD37
MTRSESLTAESRLVH	HERC1	1486	Q15751
RMISSISETELELSS	MAPK8IP2	266	Q13387
SISSKRSSVRSDAAM	JPH1	231	Q9HDC5
RSSVRSDAAMSRISS	JPH1	236	Q9HDC5
SLDRTDASTDLAMRS	CCDC88C	1496	Q9P219
ISSLSSTERGIRSEM	MACO1	411	Q8N5G2
TTLTSRRTTRITSQM	MUC3A	2931	Q02505
ISRDRLSASSLTMES	HNRNPU	301	Q00839
ATTSARNELTEMKRT	KRT25	291	Q7Z3Z0
SLSSLRSRSTQMEST	LMO7	876	Q8WWI1
RSRSTQMESTRVSAS	LMO7	881	Q8WWI1
MATTSRDSADTLRLE	NRXN1	756	Q9ULB1
IMETTTTLATSTARR	NRXN1	1321	Q9ULB1
AVDTLRSMLLRSGSE	MROH1	1266	Q8NDA8
RVLSMSRSAITAIAT	NDUFA9	11	Q16795
MSSSDEETLSERSCR	MACF1	1	Q9UPN3
DTMRHSIIETSRSSL	MFSD4B	461	Q5TF39
LSDSRTLSSSSMDLS	KLC2	601	Q9H0B6
TLSSSSMDLSRRSSL	KLC2	606	Q9H0B6
DTTATAVIMTRLSTR	HFM1	661	A2PYH4
MASTESSLLRSLGLS	P2RY4	1	P51582
RLRSQDSMSSDTART	MCM3	596	P25205
SMQFRSAESVRSLLS	PRICKLE2	596	Q7Z3G6
CRSSSMADRSSRLLE	BAG2	16	O95816
SLRKSLVTSVRAMSE	FRG2C	171	A6NGY1
MATTFSLASLRESVD	KLHL26	171	Q53HC5
LRSTSTMERLVARGT	CDKN1C	6	P49918
VTSLRMTSELESSLT	FOXJ3	11	Q9UPW0
SVRSTTRQMRSSLSA	AKNA	1411	Q7Z591
MRSSASRLSSFSSRD	ASAP1	1	Q9ULH1
RILMTKLRASTTSET	CRHR1	321	P34998
SSLVSRTRLKTLAMD	GNPDA2	151	Q8TDQ7
RLLSRIASSMSSTFF	MARCHF7	281	Q9H992
ELETRMSTRSSKAAS	ESCO1	61	Q5FWF5
IVSSSSDTRIAKRMA	FSHR	561	P23945
TSSDMRRSGTRTSES	EQTN	256	Q9NQ60
LADRSSSSTIRMDAL	CAND2	486	O75155
HTRQEASLSVTSTRM	RSC1A1	126	Q92681
SLSFRMREPLSSISS	S1PR4	366	O95977
TSSELQMRRSSLPAT	SPACA1	201	Q9HBV2
SLRSRSTRMSTVSEL	KIF2C	106	Q99661
STRMSTVSELRITAQ	KIF2C	111	Q99661
SRSLSARQLARMSES	PROCA1	281	Q8NCQ7
TLTREMITLSFRTTR	CNTNAP3B	1036	Q96NU0
DRLVSARSVSPTTEM	MET	981	P08581
SLDRMLSSSSSVSSL	SYTL1	231	Q8IYJ3
MERSQSRLSLSASFE	RIMS4	1	Q9H426
EELRRQIRSSTTSMT	PSMD2	76	Q13200
DLTRDTTSLRTKMSS	PROX1	516	Q92786
SVELLSMSSSSRIVT	HUS1	116	O60921
RRSRIMGLSESSSET	SCN9A	451	Q15858
TLSLRNSISRIMSEA	SIPA1	906	Q96FS4
LEMTLASRLSTAANT	SLC41A3	116	Q96GZ6
SMTRLARSRTASLTS	NDRG4	306	Q9ULP0
SIVRSSRTTLDRMED	WDR13	81	Q9H1Z4
RTGDLISRLTSDTTM	ABCB9	281	Q9NP78
ISQSSRLSSSVSAMR	CLASP2	576	O75122
RQRLSDMSISTSSSD	RIN2	426	Q8WYP3
TLDLASSRLDSAMAV	WDR90	876	Q96KV7
LNTTMIDTAARDTAR	SLC26A4	171	O43511
STTLTLRSKSMTAEL	SHANK3	686	Q9BYB0
EDLRISRTDSFSSMT	ARHGAP25	386	P42331
SRTDCVMISTRLVSS	TLCD3A	31	Q8TBR7
SVRSLHSESSMSLRS	TRAF7	91	Q6Q0C0
SSMLRLSLSDLEDSR	TTC41P	886	Q6P2S7
NRDLMSSSTSISSLS	PHF11	316	Q9UIL8
STSRTMESESLRTLE	TLR7	611	Q9NYK1
ELSATTRMVLDSLRT	SLC35F6	286	Q8N357
ATSATLELDRLMASL	TGFB1I1	151	O43294
TSMSLARILSLLAAS	PLBD2	536	Q8NHP8
MSRSRLFSVTSAIST	TMEM207	1	Q6UWW9
SNTLEMELSSTRLER	TRIM66	636	O15016
DIDEVSSLLRTSIMS	CCT8	156	P50990
LSMLADSTSTQEKRR	ZNF318	511	Q5VUA4
LSESEMFASELSRSL	TIPIN	181	Q9BVW5
RLVLSESCSRDSMSS	ZMYM3	1041	Q14202
MLKTESSGERTTLRS	PPP1R9A	1	Q9ULJ8
LESSVSERISRFDTM	PPP1R9A	116	Q9ULJ8