Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of synapse	POTEE POTEF PCLO POTEI PLS3	1.36e-07	42	58	5	GO:0098918
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEE POTEF POTEI	3.77e-06	11	58	3	GO:0098973
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	POTEE POTEF SPTB POTEI PLS3	3.76e-05	130	58	5	GO:0005200
GeneOntologyMolecularFunction	glucokinase activity	HK1 HKDC1	8.25e-05	5	58	2	GO:0004340
GeneOntologyMolecularFunction	hexokinase activity	HK1 HKDC1	8.25e-05	5	58	2	GO:0004396
GeneOntologyMolecularFunction	fructokinase activity	HK1 HKDC1	8.25e-05	5	58	2	GO:0008865
GeneOntologyMolecularFunction	protein serine kinase activity	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	8.39e-05	363	58	7	GO:0106310
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEE POTEF POTEI	1.09e-04	32	58	3	GO:0099186
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	AKT3 HK1 STK26 MAP3K20 DYRK1A HKDC1 PRKCA AKT1 CIT	1.91e-04	709	58	9	GO:0016773
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	2.98e-04	446	58	7	GO:0004674
GeneOntologyMolecularFunction	protein kinase activity	AKT3 HK1 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	3.23e-04	600	58	8	GO:0004672
GeneOntologyMolecularFunction	kinase activity	AKT3 HK1 STK26 MAP3K20 DYRK1A HKDC1 PRKCA AKT1 CIT	3.32e-04	764	58	9	GO:0016301
GeneOntologyMolecularFunction	histone H3 kinase activity	DYRK1A PRKCA	5.37e-04	12	58	2	GO:0140996
GeneOntologyMolecularFunction	D-glucose binding	HK1 HKDC1	7.38e-04	14	58	2	GO:0005536
GeneOntologyMolecularFunction	protein kinase binding	POTEE AKT3 CENPE FZD5 POTEF AKT1 POTEI CIT UTRN	8.69e-04	873	58	9	GO:0019901
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	AKT3 HK1 STK26 MAP3K20 DYRK1A HKDC1 PRKCA AKT1 CIT	1.44e-03	938	58	9	GO:0016772
GeneOntologyMolecularFunction	carbohydrate kinase activity	HK1 HKDC1	1.68e-03	21	58	2	GO:0019200
GeneOntologyMolecularFunction	kinase binding	POTEE AKT3 CENPE FZD5 POTEF AKT1 POTEI CIT UTRN	1.80e-03	969	58	9	GO:0019900
GeneOntologyMolecularFunction	ATP-dependent activity	EP400 CENPE DDX25 PSMC1 MYO5C HELLS HSPA13	1.94e-03	614	58	7	GO:0140657
GeneOntologyMolecularFunction	histone kinase activity	DYRK1A PRKCA	2.99e-03	28	58	2	GO:0035173
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEE EP400 POTEF POTEI	2.08e-06	32	60	4	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEE EP400 POTEF POTEI	2.08e-06	32	60	4	GO:0043189
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEE EP400 POTEF POTEI	8.37e-06	45	60	4	GO:1902562
GeneOntologyCellularComponent	protein acetyltransferase complex	POTEE EP400 POTEF POTEI NAA16	1.22e-05	104	60	5	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	POTEE EP400 POTEF POTEI NAA16	1.53e-05	109	60	5	GO:1902493
GeneOntologyCellularComponent	actin filament	POTEE POTEF DYRK1A POTEI PLS3	6.22e-05	146	60	5	GO:0005884
GeneOntologyCellularComponent	histone acetyltransferase complex	POTEE EP400 POTEF POTEI	1.54e-04	94	60	4	GO:0000123
GeneOntologyCellularComponent	axon	POTEE FZD5 POTEF PCLO FRMD7 DYRK1A PRKCA WDFY3 POTEI INPP5F	2.05e-04	891	60	10	GO:0030424
GeneOntologyCellularComponent	actin cytoskeleton	POTEE POTEF SPTB DYRK1A POTEI CIT PLS3 MYO5C	2.29e-04	576	60	8	GO:0015629
Domain	ANK	POTEB3 POTEE POTEM POTEF POTEG POTED POTEI POTEC	1.33e-06	251	60	8	SM00248
Domain	ANK_REPEAT	POTEB3 POTEE POTEM POTEF POTEG POTED POTEI POTEC	1.41e-06	253	60	8	PS50088
Domain	ANK_REP_REGION	POTEB3 POTEE POTEM POTEF POTEG POTED POTEI POTEC	1.46e-06	254	60	8	PS50297
Domain	Ankyrin_rpt	POTEB3 POTEE POTEM POTEF POTEG POTED POTEI POTEC	1.84e-06	262	60	8	IPR002110
Domain	Ank_2	POTEB3 POTEE POTEM POTEF POTEG POTEI POTEC	5.59e-06	215	60	7	PF12796
Domain	Pkinase_C	AKT3 PRKCA AKT1 CIT	5.87e-06	37	60	4	IPR017892
Domain	Ank	POTEE POTEM POTEF POTEG POTED POTEI POTEC	8.21e-06	228	60	7	PF00023
Domain	Pkinase_C	AKT3 PRKCA AKT1 CIT	9.83e-06	42	60	4	PF00433
Domain	-	POTEB3 POTEE POTEM POTEF POTEG POTEI POTEC	1.42e-05	248	60	7	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	POTEB3 POTEE POTEM POTEF POTEG POTEI POTEC	1.65e-05	254	60	7	IPR020683
Domain	Actin_CS	POTEE POTEF POTEI	1.71e-05	16	60	3	IPR004001
Domain	ACTINS_2	POTEE POTEF POTEI	2.08e-05	17	60	3	PS00432
Domain	Actin/actin-like_CS	POTEE POTEF POTEI	2.49e-05	18	60	3	IPR020902
Domain	ACTINS_ACT_LIKE	POTEE POTEF POTEI	2.94e-05	19	60	3	PS01132
Domain	AGC-kinase_C	AKT3 PRKCA AKT1 CIT	3.12e-05	56	60	4	IPR000961
Domain	AGC_KINASE_CTER	AKT3 PRKCA AKT1 CIT	3.12e-05	56	60	4	PS51285
Domain	S_TK_X	AKT3 PRKCA AKT1 CIT	3.12e-05	56	60	4	SM00133
Domain	Actinin_actin-bd_CS	SPTB UTRN PLS3	5.33e-05	23	60	3	IPR001589
Domain	ACTININ_2	SPTB UTRN PLS3	5.33e-05	23	60	3	PS00020
Domain	ACTININ_1	SPTB UTRN PLS3	5.33e-05	23	60	3	PS00019
Domain	Hexokinase_C	HK1 HKDC1	1.01e-04	5	60	2	IPR022673
Domain	Hexokinase_N	HK1 HKDC1	1.01e-04	5	60	2	IPR022672
Domain	Hexokinase_1	HK1 HKDC1	1.01e-04	5	60	2	PF00349
Domain	Hexokinase_2	HK1 HKDC1	1.01e-04	5	60	2	PF03727
Domain	HEXOKINASE_2	HK1 HKDC1	1.01e-04	5	60	2	PS51748
Domain	Hexokinase_BS	HK1 HKDC1	1.01e-04	5	60	2	IPR019807
Domain	HEXOKINASE_1	HK1 HKDC1	1.01e-04	5	60	2	PS00378
Domain	Actin	POTEE POTEF POTEI	1.33e-04	31	60	3	IPR004000
Domain	Actin	POTEE POTEF POTEI	1.33e-04	31	60	3	PF00022
Domain	ACTIN	POTEE POTEF POTEI	1.33e-04	31	60	3	SM00268
Domain	S_TKc	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	1.47e-04	359	60	7	SM00220
Domain	Hexokinase	HK1 HKDC1	1.51e-04	6	60	2	IPR001312
Domain	PROTEIN_KINASE_ST	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	1.55e-04	362	60	7	PS00108
Domain	PROTEIN_KINASE_ATP	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	6.49e-04	459	60	7	PS00107
Domain	CNH	VPS39 CIT	9.01e-04	14	60	2	SM00036
Domain	Prot_kinase_dom	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	9.41e-04	489	60	7	IPR000719
Domain	Ser/Thr_kinase_AS	AKT3 MAP3K20 DYRK1A PRKCA AKT1 CIT	9.82e-04	357	60	6	IPR008271
Domain	PROTEIN_KINASE_DOM	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	9.86e-04	493	60	7	PS50011
Domain	CNH	VPS39 CIT	1.04e-03	15	60	2	PF00780
Domain	CNH	VPS39 CIT	1.04e-03	15	60	2	PS50219
Domain	CNH_dom	VPS39 CIT	1.04e-03	15	60	2	IPR001180
Domain	CH	SPTB UTRN PLS3	1.19e-03	65	60	3	SM00033
Domain	Protein_kinase_ATP_BS	AKT3 STK26 DYRK1A PRKCA AKT1 CIT	1.33e-03	379	60	6	IPR017441
Domain	Pkinase	AKT3 STK26 DYRK1A PRKCA AKT1 CIT	1.37e-03	381	60	6	PF00069
Domain	CH	SPTB UTRN PLS3	1.48e-03	70	60	3	PF00307
Domain	-	SPTB UTRN PLS3	1.54e-03	71	60	3	1.10.418.10
Domain	CH	SPTB UTRN PLS3	1.67e-03	73	60	3	PS50021
Domain	Kinase-like_dom	AKT3 STK26 MAP3K20 DYRK1A PRKCA AKT1 CIT	1.70e-03	542	60	7	IPR011009
Domain	CH-domain	SPTB UTRN PLS3	1.81e-03	75	60	3	IPR001715
Domain	PH_dom-like	AKT3 FRMD7 AKT1 WDFY3 PLEKHA7 CIT	2.41e-03	426	60	6	IPR011993
Domain	Spectrin	SPTB UTRN	2.46e-03	23	60	2	PF00435
Domain	Spectrin_repeat	SPTB UTRN	3.90e-03	29	60	2	IPR002017
Domain	SNF2_N	EP400 HELLS	4.73e-03	32	60	2	IPR000330
Domain	Spectrin/alpha-actinin	SPTB UTRN	4.73e-03	32	60	2	IPR018159
Domain	SNF2_N	EP400 HELLS	4.73e-03	32	60	2	PF00176
Domain	SPEC	SPTB UTRN	4.73e-03	32	60	2	SM00150
Domain	Helicase_C	EP400 DDX25 HELLS	4.94e-03	107	60	3	PF00271
Domain	HELICc	EP400 DDX25 HELLS	4.94e-03	107	60	3	SM00490
Domain	Helicase_C	EP400 DDX25 HELLS	5.07e-03	108	60	3	IPR001650
Domain	HELICASE_CTER	EP400 DDX25 HELLS	5.20e-03	109	60	3	PS51194
Domain	HELICASE_ATP_BIND_1	EP400 DDX25 HELLS	5.20e-03	109	60	3	PS51192
Domain	DEXDc	EP400 DDX25 HELLS	5.20e-03	109	60	3	SM00487
Domain	Helicase_ATP-bd	EP400 DDX25 HELLS	5.33e-03	110	60	3	IPR014001
Domain	PH	AKT3 AKT1 PLEKHA7 CIT	6.28e-03	229	60	4	PF00169
Pathway	WP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS	AKT3 PRKCA AKT1 PDCD4	9.20e-06	46	41	4	M39805
Pathway	WP_T_CELL_RECEPTOR_AND_COSTIMULATORY_SIGNALING	DYRK1A PRKCA AKT1	7.11e-05	28	41	3	M39632
Pathway	KEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	8.21e-05	5	41	2	M48999
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS	HK1 HKDC1	1.23e-04	6	41	2	M47654
Pathway	KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY	AKT3 AKT1	1.23e-04	6	41	2	M47523
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	1.72e-04	7	41	2	M47407
Pathway	KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	1.72e-04	7	41	2	M47790
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47399
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47394
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47395
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47404
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47405
Pathway	KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47803
Pathway	REACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION	AKT3 AKT1	2.29e-04	8	41	2	M27806
Pathway	KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47482
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47498
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.29e-04	8	41	2	M47715
Pathway	BIOCARTA_PLC_PATHWAY	PRKCA AKT1	2.93e-04	9	41	2	M22029
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47397
Pathway	BIOCARTA_PLC_PATHWAY	PRKCA AKT1	2.93e-04	9	41	2	MM1551
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47392
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47391
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47402
Pathway	KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47802
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47490
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47481
Pathway	REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING	AKT3 AKT1	2.93e-04	9	41	2	MM15666
Pathway	KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	2.93e-04	9	41	2	M47972
Pathway	KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	3.66e-04	10	41	2	M47400
Pathway	KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	3.66e-04	10	41	2	M47401
Pathway	KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	3.66e-04	10	41	2	M47615
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS	AKT3 AKT1	3.66e-04	10	41	2	M27095
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS	AKT3 AKT1	3.66e-04	10	41	2	MM14778
Pathway	WP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY	AKT3 PRKCA AKT1	4.07e-04	50	41	3	M48087
Pathway	REACTOME_SIGNALING_BY_ERBB2	AKT3 PRKCA AKT1	4.07e-04	50	41	3	M553
Pathway	KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	4.46e-04	11	41	2	M47797
Pathway	KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	4.46e-04	11	41	2	M47403
Pathway	KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	4.46e-04	11	41	2	M47406
Pathway	KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	4.46e-04	11	41	2	M47484
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	4.46e-04	11	41	2	M47499
Pathway	KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	4.46e-04	11	41	2	M47756
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339	AKT3 AKT1	4.46e-04	11	41	2	M47791
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	4.46e-04	11	41	2	M47501
Pathway	KEGG_NON_SMALL_CELL_LUNG_CANCER	AKT3 PRKCA AKT1	5.11e-04	54	41	3	M19818
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	5.35e-04	12	41	2	M47393
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350	AKT3 AKT1	5.35e-04	12	41	2	M47798
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY	AKT3 AKT1	5.35e-04	12	41	2	M47558
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY	AKT3 AKT1	5.35e-04	12	41	2	M47559
Pathway	REACTOME_SARS_COV_2_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS	AKT3 AKT1	5.35e-04	12	41	2	M45022
Pathway	REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS	AKT3 AKT1	5.35e-04	12	41	2	MM15657
Pathway	REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS	AKT3 AKT1	5.35e-04	12	41	2	M27939
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	AKT3 AKT1	5.35e-04	12	41	2	MM14777
Pathway	REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING	AKT3 AKT1	5.35e-04	12	41	2	MM14550
Pathway	REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	AKT3 DYRK1A PSMC1 AKT1	5.37e-04	130	41	4	MM15146
Pathway	KEGG_TIGHT_JUNCTION	AKT3 MAP3K20 PRKCA AKT1	5.69e-04	132	41	4	M11355
Pathway	KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	6.31e-04	13	41	2	M47398
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	6.31e-04	13	41	2	M47603
Pathway	REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING	AKT3 AKT1	6.31e-04	13	41	2	M549
Pathway	KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	7.35e-04	14	41	2	M47390
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS	AKT3 AKT1	7.35e-04	14	41	2	MM15341
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS	AKT3 AKT1	7.35e-04	14	41	2	M27638
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY	AKT3 AKT1	7.35e-04	14	41	2	M47467
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY	AKT3 AKT1	7.35e-04	14	41	2	M47536
Pathway	BIOCARTA_TRKA_PATHWAY	PRKCA AKT1	7.35e-04	14	41	2	M9134
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	AKT3 AKT1	7.35e-04	14	41	2	M3862
Pathway	BIOCARTA_TRKA_PATHWAY	PRKCA AKT1	8.46e-04	15	41	2	MM1523
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	8.46e-04	15	41	2	M47389
Pathway	KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	8.46e-04	15	41	2	M47663
Pathway	REACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA	AKT3 AKT1	8.46e-04	15	41	2	M26902
Pathway	KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	8.46e-04	15	41	2	M47475
Pathway	WP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS	AKT3 AKT1	8.46e-04	15	41	2	M48306
Pathway	KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY	AKT3 AKT1	8.46e-04	15	41	2	M47971
Pathway	KEGG_GLIOMA	AKT3 PRKCA AKT1	8.80e-04	65	41	3	M1835
Pathway	REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	AKT3 DYRK1A PSMC1 AKT1	8.96e-04	149	41	4	M848
Pathway	REACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY	AKT3 PSMC1 AKT1	1.05e-03	69	41	3	MM15540
Pathway	REACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY	AKT3 PSMC1 AKT1	1.05e-03	69	41	3	M27815
Pathway	PID_MTOR_4PATHWAY	PRKCA AKT1 PDCD4	1.05e-03	69	41	3	M121
Pathway	WP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES	AKT3 AKT1	1.09e-03	17	41	2	M48086
Pathway	BIOCARTA_TEL_PATHWAY	PRKCA AKT1	1.09e-03	17	41	2	MM1508
Pathway	SA_PTEN_PATHWAY	AKT3 AKT1	1.09e-03	17	41	2	M12771
Pathway	BIOCARTA_TEL_PATHWAY	PRKCA AKT1	1.09e-03	17	41	2	M10401
Pathway	SA_TRKA_RECEPTOR	AKT3 AKT1	1.09e-03	17	41	2	M18895
Pathway	REACTOME_CYCLIN_A_CDK2_ASSOCIATED_EVENTS_AT_S_PHASE_ENTRY	AKT3 PSMC1 AKT1	1.09e-03	70	41	3	MM15389
Pathway	WP_NONSMALL_CELL_LUNG_CANCER	AKT3 PRKCA AKT1	1.18e-03	72	41	3	M39738
Pathway	BIOCARTA_CHEMICAL_PATHWAY	PRKCA AKT1	1.23e-03	18	41	2	MM1350
Pathway	BIOCARTA_CHEMICAL_PATHWAY	PRKCA AKT1	1.23e-03	18	41	2	M3873
Pathway	WP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION	AKT3 AKT1	1.37e-03	19	41	2	M39370
Pathway	KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY	AKT3 AKT1	1.37e-03	19	41	2	M47525
Pathway	KEGG_VEGF_SIGNALING_PATHWAY	AKT3 PRKCA AKT1	1.39e-03	76	41	3	M1749
Pathway	REACTOME_KEAP1_NFE2L2_PATHWAY	AKT3 PSMC1 AKT1	1.44e-03	77	41	3	MM15698
Pathway	BIOCARTA_CREB_PATHWAY	PRKCA AKT1	1.52e-03	20	41	2	MM1520
Pathway	BIOCARTA_EDG1_PATHWAY	PRKCA AKT1	1.52e-03	20	41	2	MM1456
Pathway	BIOCARTA_ARENRF2_PATHWAY	CRYZ PRKCA	1.52e-03	20	41	2	M14339
Pathway	KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY	AKT3 PRKCA AKT1	1.55e-03	79	41	3	M11816
Pathway	REACTOME_SARS_COV_2_INFECTION	AKT3 VPS39 RPS9 AKT1 ANO8	1.66e-03	299	41	5	M41727
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	AKT3 AKT1	1.67e-03	21	41	2	M14966
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	AKT3 AKT1	1.67e-03	21	41	2	M5876
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	AKT3 AKT1	1.67e-03	21	41	2	MM14996
Pathway	REACTOME_APOPTOSIS	AKT3 STK26 PSMC1 AKT1	1.76e-03	179	41	4	M15303
Pathway	WP_GLIOBLASTOMA_SIGNALING	AKT3 PRKCA AKT1	1.79e-03	83	41	3	M39637
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEE POTEM POTEF POTEG POTEI	4.16e-11	15	61	5	16824795
Pubmed	Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.	POTEB3 POTEE POTEG POTED	2.98e-10	7	61	4	15276201
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	POTEB3 POTEE POTEM POTEF PCLO POTEG POTEI POTEC	4.67e-10	163	61	8	24316575
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEE POTEM POTED POTEI	1.07e-09	9	61	4	16364570
Pubmed	Phospho-tyrosine dependent protein-protein interaction network.	VPS39 STK26 SPTB PSMC1 PRKCA AKT1 WDFY3 MNDA NAA16 OTUD7B	2.45e-09	410	61	10	25814554
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEM POTEG POTEC	1.02e-07	6	61	3	17171436
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DNAJC13 HK1 PCLO STK26 SPTB CALCOCO1 RPS9 DYRK1A PSMC1 PRKCA PLEKHA7 CIT UTRN PLS3	1.37e-07	1431	61	14	37142655
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEB3 POTED POTEC	2.86e-07	8	61	3	12475935
Pubmed	Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Cα in chondrocytes.	PRKCA AKT1	3.03e-06	2	61	2	22532149
Pubmed	Akt phosphorylates and regulates Pdcd4 tumor suppressor protein.	AKT1 PDCD4	3.03e-06	2	61	2	16357133
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEE POTEF	3.03e-06	2	61	2	19669888
Pubmed	Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver.	CYP2E1 AKT1	3.03e-06	2	61	2	28987868
Pubmed	Rarity of AKT1 and AKT3 E17K mutations in squamous cell carcinoma of lung.	AKT3 AKT1	3.03e-06	2	61	2	20980808
Pubmed	Impaired Spatial Learning is Associated with Disrupted Integrity of the White Matter in Akt3 Knockout Mice.	AKT3 AKT1	3.03e-06	2	61	2	27671373
Pubmed	AKT isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans.	AKT3 AKT1	3.03e-06	2	61	2	23303682
Pubmed	Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy.	AKT1 UTRN	3.03e-06	2	61	2	18986978
Pubmed	Akt3 deletion in mice impairs spatial cognition and hippocampal CA1 long long-term potentiation through downregulation of mTOR.	AKT3 AKT1	3.03e-06	2	61	2	30053339
Pubmed	Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells.	AKT3 AKT1	3.03e-06	2	61	2	21777670
Pubmed	Akt1 and akt3 exert opposing roles in the regulation of vascular tumor growth.	AKT3 AKT1	3.03e-06	2	61	2	25388284
Pubmed	Dual expression of shAkt1 and Pdcd4 suppresses lung tumorigenesis in K-rasLA1 mice.	AKT1 PDCD4	3.03e-06	2	61	2	25862855
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	POTEE EP400 STRBP POTEF RPS9 POTEI	8.21e-06	271	61	6	32433965
Pubmed	Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis.	AKT3 AKT1 CIT	8.87e-06	23	61	3	11086988
Pubmed	Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.	AKT3 AKT1	9.07e-06	3	61	2	19805051
Pubmed	Deletion of PKBalpha/Akt1 affects thymic development.	AKT3 AKT1	9.07e-06	3	61	2	17912369
Pubmed	Differential activation of AKT isoforms by growth factors in human myotubes.	AKT3 AKT1	9.07e-06	3	61	2	37879895
Pubmed	Signalling specificity in the Akt pathway in breast cancer.	AKT3 AKT1	9.07e-06	3	61	2	25233414
Pubmed	Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.	AKT3 AKT1	9.07e-06	3	61	2	21555366
Pubmed	Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency.	AKT3 AKT1	9.07e-06	3	61	2	32796067
Pubmed	All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.	AKT3 AKT1	9.07e-06	3	61	2	25811375
Pubmed	Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development.	AKT3 AKT1	9.07e-06	3	61	2	20724596
Pubmed	Differential prognostic values of the three AKT isoforms in acute myeloid leukemia.	AKT3 AKT1	9.07e-06	3	61	2	38528080
Pubmed	Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS.	AKT3 AKT1	9.07e-06	3	61	2	27098694
Pubmed	Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2.	AKT3 AKT1	9.07e-06	3	61	2	15987444
Pubmed	Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action.	AKT3 AKT1	9.07e-06	3	61	2	27076519
Pubmed	Role of Akt isoforms in IGF-I-mediated signaling and survival in myoblasts.	AKT3 AKT1	9.07e-06	3	61	2	19703413
Pubmed	MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.	AKT3 AKT1	9.07e-06	3	61	2	19825827
Pubmed	Kinetic mechanism of AKT/PKB enzyme family.	AKT3 AKT1	9.07e-06	3	61	2	16540465
Pubmed	Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice.	AKT3 AKT1	9.07e-06	3	61	2	22632897
Pubmed	Variation in Akt protein kinases in human populations.	AKT3 AKT1	9.07e-06	3	61	2	28931550
Pubmed	Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH.	AKT3 AKT1	9.07e-06	3	61	2	20102399
Pubmed	Cellular survival: a play in three Akts.	AKT3 AKT1	9.07e-06	3	61	2	10579998
Pubmed	Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.	AKT3 AKT1	9.07e-06	3	61	2	20398329
Pubmed	Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.	AKT3 AKT1	9.07e-06	3	61	2	18561256
Pubmed	Differential effects of Akt isoforms on somatic cell reprogramming.	AKT3 AKT1	9.07e-06	3	61	2	25037569
Pubmed	All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines.	AKT3 AKT1	9.07e-06	3	61	2	38396845
Pubmed	Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders.	AKT3 AKT1	9.07e-06	3	61	2	33325370
Pubmed	AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity.	AKT3 AKT1	9.07e-06	3	61	2	29173281
Pubmed	Akt/PKB isoforms expression in the human lumbar herniated disc: correlation with clinical and MRI findings.	AKT3 AKT1	9.07e-06	3	61	2	21590431
Pubmed	Protein kinase Akt activity in human thyroid tumors.	AKT3 AKT1	9.07e-06	3	61	2	29235817
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEE POTEF	9.07e-06	3	61	2	17101985
Pubmed	Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease.	AKT3 AKT1	9.07e-06	3	61	2	34296180
Pubmed	The Akt isoforms are present at distinct subcellular locations.	AKT3 AKT1	9.07e-06	3	61	2	20018949
Pubmed	Identification of AKT kinases as unfavorable prognostic factors for hepatocellular carcinoma by a combination of expression profile, interaction network analysis and clinical validation.	AKT3 AKT1	9.07e-06	3	61	2	24247267
Pubmed	Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.	AKT3 AKT1	9.07e-06	3	61	2	17982014
Pubmed	Dissociation of gemcitabine sensitivity and protein kinase B signaling in pancreatic ductal adenocarcinoma models.	AKT3 AKT1	9.07e-06	3	61	2	17895832
Pubmed	Opposing functions of Akt isoforms in lung tumor initiation and progression.	AKT3 AKT1	9.07e-06	3	61	2	24722238
Pubmed	Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C.	PRKCA AKT1	9.07e-06	3	61	2	19324870
Pubmed	Caspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylation.	AKT3 AKT1	9.07e-06	3	61	2	17544405
Pubmed	ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer.	ADAMTS9 AKT1	9.07e-06	3	61	2	22907434
Pubmed	Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice.	DYRK1A AKT1	9.07e-06	3	61	2	22923366
Pubmed	The AKT genes and their roles in various disorders.	AKT3 AKT1	9.07e-06	3	61	2	24039187
Pubmed	Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3.	AKT3 AKT1	9.07e-06	3	61	2	10491192
Pubmed	Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies.	AKT3 AKT1	9.07e-06	3	61	2	16923958
Pubmed	Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death.	AKT3 AKT1	9.07e-06	3	61	2	17202487
Pubmed	Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer.	AKT3 AKT1	9.07e-06	3	61	2	26953242
Pubmed	Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme.	PRKCA AKT1	9.07e-06	3	61	2	18622039
Pubmed	Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.	AKT3 AKT1	9.07e-06	3	61	2	17210696
Pubmed	Role for Akt3/protein kinase Bgamma in attainment of normal brain size.	AKT3 AKT1	9.07e-06	3	61	2	15713641
Pubmed	Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay.	AKT3 AKT1	9.07e-06	3	61	2	23929892
Pubmed	Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.	AKT3 PRKCA AKT1	1.15e-05	25	61	3	15689238
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GDAP1L1 MIA2 ADAMTS9 VPS39 SPTB DYRK1A PSMC1 WDFY3 CIT UTRN HSPA13	1.29e-05	1285	61	11	35914814
Pubmed	Multistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin.	PRKCA AKT1	1.81e-05	4	61	2	21750658
Pubmed	Photoreceptor Neuroprotection: Regulation of Akt Activation Through Serine/Threonine Phosphatases, PHLPP and PHLPPL.	AKT3 AKT1	1.81e-05	4	61	2	26427440
Pubmed	Hexokinase activity is required for recruitment of parkin to depolarized mitochondria.	HK1 AKT1	1.81e-05	4	61	2	23962723
Pubmed	EGFR signals to mTOR through PKC and independently of Akt in glioma.	PRKCA AKT1	1.81e-05	4	61	2	19176518
Pubmed	The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt.	PRKCA AKT1	1.81e-05	4	61	2	15448167
Pubmed	Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos.	AKT3 AKT1	1.81e-05	4	61	2	31552693
Pubmed	Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism.	AKT3 AKT1	1.81e-05	4	61	2	19435822
Pubmed	Hepatocyte-specific Dyrk1a gene transfer rescues plasma apolipoprotein A-I levels and aortic Akt/GSK3 pathways in hyperhomocysteinemic mice.	DYRK1A AKT1	1.81e-05	4	61	2	23429073
Pubmed	Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively.	PRKCA AKT1	1.81e-05	4	61	2	21705328
Pubmed	Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.	AKT3 AKT1	1.81e-05	4	61	2	21507933
Pubmed	Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.	AKT3 AKT1	1.81e-05	4	61	2	19933838
Pubmed	S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt.	AKT3 AKT1	1.81e-05	4	61	2	21906027
Pubmed	Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain.	AKT3 AKT1	1.81e-05	4	61	2	26227811
Pubmed	Cell invasion of Yersinia pseudotuberculosis by invasin and YadA requires protein kinase C, phospholipase C-gamma1 and Akt kinase.	PRKCA AKT1	1.81e-05	4	61	2	19681907
Pubmed	Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.	AKT3 AKT1	1.81e-05	4	61	2	17942896
Pubmed	Akt1 deletion prevents lung tumorigenesis by mutant K-ras.	AKT3 AKT1	1.81e-05	4	61	2	21242979
Pubmed	Programmed cell death 4 (PDCD4) enhances the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by inhibiting the PI3K/Akt signaling pathway.	AKT1 PDCD4	1.81e-05	4	61	2	20560677
Pubmed	Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.	AKT3 AKT1	1.81e-05	4	61	2	30567482
Pubmed	Human immunodeficiency virus type 1 induces lytic cycle replication of Kaposi's-sarcoma-associated herpesvirus: role of Ras/c-Raf/MEK1/2, PI3K/AKT, and NF-κB signaling pathways.	AKT3 AKT1	1.81e-05	4	61	2	21763505
Pubmed	GLUT5 regulation by AKT1/3-miR-125b-5p downregulation induces migratory activity and drug resistance in TLR-modified colorectal cancer cells.	AKT3 AKT1	1.81e-05	4	61	2	32649737
Pubmed	Identification and characterization of TSAP, a novel gene specifically expressed in testis during spermatogenesis.	POTEM POTEC	1.81e-05	4	61	2	17342726
Pubmed	Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.	PRKCA AKT1	1.81e-05	4	61	2	28264193
Pubmed	Phosphorylation of CK1delta: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivo.	PRKCA AKT1	1.81e-05	4	61	2	17594292
Pubmed	Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.	AKT3 STK26 CALCOCO1 MAP3K20 AKT1	2.94e-05	203	61	5	19953087
Pubmed	Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.	TMEM67 TMEM62 HK1 RAPGEFL1	2.96e-05	100	61	4	26073538
Pubmed	Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.	AKT3 AKT1	3.02e-05	5	61	2	19289493
Pubmed	The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.	AKT3 AKT1	3.02e-05	5	61	2	20059950
Pubmed	Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.	AKT3 AKT1	3.02e-05	5	61	2	9512493
Pubmed	Characterization of PDK2 activity against protein kinase B gamma.	AKT3 PRKCA	3.02e-05	5	61	2	12162751
Interaction	POTEC interactions	POTEB3 POTEF POTEG POTED POTEC	2.71e-10	13	61	5	int:POTEC
Interaction	POTED interactions	POTEB3 POTED POTEC	1.05e-07	4	61	3	int:POTED
Interaction	POTEB3 interactions	POTEB3 POTEF POTED POTEC	3.71e-06	35	61	4	int:POTEB3
Interaction	HMGN2 interactions	PCLO PRKCA POTEI CIT UTRN PDCD4 MYO5C	4.71e-06	222	61	7	int:HMGN2
Interaction	POTEG interactions	POTEF POTEG POTEC	5.69e-06	12	61	3	int:POTEG
Interaction	POTEM interactions	POTEM CIT	2.70e-05	3	61	2	int:POTEM
Interaction	KCTD13 interactions	DNAJC13 HK1 PCLO STK26 SPTB CALCOCO1 RPS9 DYRK1A PSMC1 PRKCA PLEKHA7 CIT UTRN PLS3	5.56e-05	1394	61	14	int:KCTD13
Cytoband	2q21.1	POTEE POTEF POTEI	6.54e-05	58	61	3	2q21.1
Cytoband	11q24	KCNJ5 DDX25	2.06e-04	16	61	2	11q24
Cytoband	10q24.2	CUTC HELLS	3.94e-04	22	61	2	10q24.2
Cytoband	Xq26.2	STK26 FRMD7	6.42e-04	28	61	2	Xq26.2
Cytoband	Ensembl 112 genes in cytogenetic band chr2q21	POTEE POTEF POTEI	1.09e-03	151	61	3	chr2q21
Cytoband	Ensembl 112 genes in cytogenetic band chr21q11	POTED HSPA13	1.81e-03	47	61	2	chr21q11
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEE POTEM POTEF POTEG POTED POTEI POTEC	4.37e-16	13	43	7	685
GeneFamily	Ankyrin repeat domain containing	POTEE POTEM POTEF POTEG POTED POTEI POTEC	1.51e-06	242	43	7	403
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AKT3 SPTB AKT1 PLEKHA7	1.43e-03	206	43	4	682
Coexpression	RAO_BOUND_BY_SALL4_ISOFORM_B	POTEB3 POTEE TMEM67 GDAP1L1 POTEM POTEF PCLO POTEG POTEI POTEC	9.07e-07	584	61	10	MM1080
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000	DNAJC13 CENPE ADAMTS9 STK26 WDFY3 CIT UTRN HELLS	3.38e-06	323	60	8	gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_500	DNAJC13 CENPE ADAMTS9 STK26 UTRN HELLS	6.18e-06	161	60	6	gudmap_developingGonad_e12.5_ovary_k3_500
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500	DNAJC13 CENPE WDFY3 UTRN HELLS	6.57e-05	150	60	5	gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000	DNAJC13 STRBP STK26 WDFY3 UTRN HELLS	7.22e-05	249	60	6	gudmap_developingGonad_P2_epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	DNAJC13 ADAMTS9 STK26 INPP5F UTRN HELLS	1.24e-04	275	60	6	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000	DNAJC13 STK26 WDFY3 CIT UTRN HELLS	1.29e-04	277	60	6	gudmap_developingGonad_e12.5_ovary_k3_1000
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D8 TBC1D30 STRBP PCLO PLEKHA7 MYO5C	2.93e-07	200	60	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11\|TCGA-Brain / Sample_Type by Project: Shred V9	POTEE POTEF POTEG POTEI	1.60e-06	63	60	4	d7dc1356a60cb527fe668328d5375f352239d911
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 SPTB PRKCA SLFN14 OTUD7B	4.20e-06	178	60	5	9e1f2596fcea5b79cc50b58d83706bb8605e224f
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 SPTB PRKCA SLFN14 OTUD7B	4.20e-06	178	60	5	aa659bd283c4dfbe292cd8698bbf6b1999ca3314
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 SPTB PRKCA SLFN14 OTUD7B	4.20e-06	178	60	5	bf1d273802a4f42e52ea1bd2a0cae2039559c093
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-9\|TCGA-Breast / Sample_Type by Project: Shred V9	POTEE POTEM POTEF POTEI	6.70e-06	90	60	4	96e836c7a1df279ac812b7c3aa75e6b81b614244
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK26 RPS9 RAPGEFL1 HELLS	5.83e-05	156	60	4	6f8622716bad4e505f241a2a4ef953bf3fc6dbfa
ToppCell	COVID-19_Moderate-MAIT\|COVID-19_Moderate / disease group, cell group and cell class	CYP2E1 DDX25 PLEKHA7 PDCD4	6.28e-05	159	60	4	6d08d670c34eb6bb8ad5dad3293b3107c006236d
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ5 SPTB HKDC1 SLFN14	6.43e-05	160	60	4	56e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ5 SPTB HKDC1 SLFN14	6.43e-05	160	60	4	bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ5 SPTB HKDC1 SLFN14	6.59e-05	161	60	4	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	EFCAB12 TTC12 MAP3K20 PLEKHA7	8.32e-05	171	60	4	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HK1 STK26 FRMD7 ANO8	8.32e-05	171	60	4	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 SPTB PRKCA SLFN14	8.51e-05	172	60	4	e39ea2f4edbf36ebf9604fa6f9349081859c596c
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 SPTB PRKCA SLFN14	8.51e-05	172	60	4	875ea290840e835952623b905eb610f3c71456d2
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 SPTB PRKCA SLFN14	8.51e-05	172	60	4	bcc50bed47465daa953ba91f17d1ee4c947ab461
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D30 STK26 CIT HELLS	8.90e-05	174	60	4	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D30 STK26 CIT HELLS	8.90e-05	174	60	4	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 PRKCA SLFN14 OTUD7B	9.51e-05	177	60	4	84591e28482ab62a5ef41e61043eb64912766356
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 PRKCA SLFN14 OTUD7B	9.51e-05	177	60	4	4bc100062891d07cacd10ffba38966cc6302c92f
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNJ5 PRKCA SLFN14 OTUD7B	9.51e-05	177	60	4	9f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE POTEF POTEG POTEI	1.01e-04	180	60	4	fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE POTEF POTEG POTEI	1.01e-04	180	60	4	beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AKT3 PRKCA PLS3 HELLS	1.01e-04	180	60	4	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	P15-Endothelial-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPE KCNJ5 CIT HELLS	1.04e-04	181	60	4	0c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCell	P15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPE KCNJ5 CIT HELLS	1.04e-04	181	60	4	f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS9 CIT UTRN PLS3	1.04e-04	181	60	4	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D8 CYP2E1 PRKCA MNDA	1.04e-04	181	60	4	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	CRYZ CENPE CIT HELLS	1.06e-04	182	60	4	9adf90bb2808f234d53b89ca0ae07380478204ad
ToppCell	normal_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	TMEM67 CRYZ CENPE OTUD7B	1.06e-04	182	60	4	8dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	CRYZ CENPE CIT HELLS	1.08e-04	183	60	4	df8568751205313d149939ea2683097e3652a60b
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UTRN PLS3 MYO5C OTUD7B	1.10e-04	184	60	4	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UTRN PLS3 MYO5C OTUD7B	1.10e-04	184	60	4	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPE RPS9 CIT HELLS	1.15e-04	186	60	4	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPE RPS9 CIT HELLS	1.15e-04	186	60	4	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_D3\|368C / Donor, Lineage, Cell class and subclass (all cells)	STK26 DYRK1A INPP5F HELLS	1.20e-04	188	60	4	ecc2364d946f97ae0212fd6739960c9fc75e4919
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AKT3 PRKCA PLS3 HELLS	1.22e-04	189	60	4	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	AKT3 WDFY3 PLEKHA7 UTRN	1.22e-04	189	60	4	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D8 TMEM67 STRBP HELLS	1.27e-04	191	60	4	683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PCLO HKDC1 PRKCA MYO5C	1.30e-04	192	60	4	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CENPE PRKCA CIT HELLS	1.33e-04	193	60	4	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 STRBP MYO5C HELLS	1.35e-04	194	60	4	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	CENPE CIT MNDA HELLS	1.35e-04	194	60	4	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	CENPE SPTB CIT HELLS	1.38e-04	195	60	4	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	(0)_NK_cells-(0)_NK_CD160pos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	STRBP PRKCA PDCD4 NAA16	1.38e-04	195	60	4	6cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCell	(00)_Basal-(0)_Reference\|(00)_Basal / shred by cell type by condition	POTEF RPS9 PDCD4 RAPGEFL1	1.41e-04	196	60	4	ba03530a20d7b29902721fd50df8d860557ddefa
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DYRK1A PRKCA WDFY3 PLEKHA7	1.46e-04	198	60	4	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	mild_COVID-19-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	CENPE CIT PLS3 HELLS	1.49e-04	199	60	4	d44cc74d7171d96add61dae821daf774b17d4c69
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	DYRK1A PRKCA WDFY3 UTRN	1.49e-04	199	60	4	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
Drug	2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A	AKT3 MIA2 TBC1D30 CYP2E1 KCNJ5 CIDEC SPTB UTRN	4.38e-08	195	60	8	4433_DN
Drug	2-cresol	CYP2E1 PRKCA AKT1	4.88e-06	13	60	3	ctd:C034047
Drug	7 palmitoleic acid	HK1 CALCOCO1	6.83e-06	2	60	2	CID005282744
Drug	arachidonyl trifluoromethyl ketone; Down 200; 10uM; MCF7; HG-U133A	AKT3 TMEM62 VPS39 KCNJ5 SPTB PDCD4	1.25e-05	195	60	6	327_DN
Drug	Captopril [62571-86-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A	TMEM62 MIA2 TBC1D30 EP400 CIDEC TTC12	1.40e-05	199	60	6	1488_DN
Disease	serum alanine aminotransferase measurement	TBC1D8 ADAMTS9 PCLO MAP3K20 DYRK1A HKDC1 PRKCA OTUD7B	1.31e-04	869	52	8	EFO_0004735
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	TMEM67 AKT1	3.60e-04	16	52	2	DOID:0110861 (implicated_via_orthology)
Disease	lateral occipital cortex volume measurement	PRKCA UTRN	4.07e-04	17	52	2	EFO_0010311
Disease	Cardiac Hypertrophy	CYP2E1 PRKCA AKT1	4.14e-04	82	52	3	C1383860
Disease	Cardiomegaly	CYP2E1 PRKCA AKT1	4.14e-04	82	52	3	C0018800
Disease	Adenocarcinoma of lung (disorder)	HK1 STRBP AKT1 HELLS	4.81e-04	206	52	4	C0152013
Disease	Malignant neoplasm of breast	CUTC MIA2 VPS39 STRBP RPS9 AKT1 PLS3 PDCD4	5.45e-04	1074	52	8	C0006142
Disease	prostate adenocarcinoma (is_implicated_in)	AKT3 AKT1	5.67e-04	20	52	2	DOID:2526 (is_implicated_in)
Disease	malignant astrocytoma (is_marker_for)	AKT3 AKT1	7.53e-04	23	52	2	DOID:3069 (is_marker_for)
Disease	type 2 diabetes mellitus (implicated_via_orthology)	AKT3 ADAMTS9 AKT1	8.52e-04	105	52	3	DOID:9352 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement	TBC1D8 CUTC DNAJC13 ADAMTS9 HKDC1 PRKCA INPP5F	9.96e-04	904	52	7	EFO_0004736
Disease	glucose metabolism disease (implicated_via_orthology)	HK1 HKDC1	1.12e-03	28	52	2	DOID:4194 (implicated_via_orthology)
Disease	progressive supranuclear palsy	TBC1D8 HK1	1.37e-03	31	52	2	MONDO_0019037
Disease	hypertension (implicated_via_orthology)	PRKCA AKT1 PLEKHA7	1.51e-03	128	52	3	DOID:10763 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FGILDKKKMEELLLL	TMEM62	201	Q0P6H9
VYRDLKLENLMLDKD	AKT1	271	P31749
AKEAELPLLDLMKLY	EP400	976	Q96L91
KFKDLILRMLDYDPK	DYRK1A	451	Q13627
YIIKDLEKLLMIAGE	CIT	1636	O14578
ELRLKEELLKGIYAM	DDX25	101	Q9UHL0
EDILMKALLYPGDKI	EFCAB12	411	Q6NXP0
KIVYRDLKLENLMLD	AKT3	266	Q9Y243
IGFYLKDMERLKEML	ANO8	456	Q9HCE9
KYVGEKGIDIIIEML	CRYZ	211	Q08257
DDLLKKLLKGEMLSY	C9orf64	256	Q5T6V5
GLLILMKYPEIEEKL	CYP2E1	311	P05181
YLKKILGELAMVLDQ	GDAP1L1	226	Q96MZ0
ELAEMKREGRLLQYL	KCNJ5	366	P48544
LMLRKALYALMEKGV	OTUD7B	211	Q6GQQ9
DKLMAKALLLYGADI	POTEF	251	A5A3E0
LDPKELMELLKSRDY	HELLS	766	Q9NRZ9
LLLDIARKLDMYGIR	FRMD7	176	Q6ZUT3
EKEIDAKLRYLEMGI	PCLO	3791	Q9Y6V0
HLVKEIDMLLKEYLL	PDCD4	326	Q53EL6
YKVREIIQKLMLDGD	PLS3	51	P13797
LKDYDMALKLLEEFR	NAA16	161	Q6N069
YLGELVRLILVKMAK	HK1	301	P19367
DKLMAKALLLYGADI	POTEB3	251	A0JP26
DKLMAKALLLYGADI	POTEE	251	Q6S8J3
DKLEKLMIRIGIFTL	FZD5	441	Q13467
DGEYFLMIRGKLLKI	ADAMTS9	1751	Q9P2N4
IIKEAMAKGALIYLL	DNAJC13	1846	O75165
KRLLLLEEEDLKDMG	MAP3K20	376	Q9NYL2
IEVMKADIRLAKLYG	CUTC	96	Q9NTM9
YVGSRLLLKLKEMAE	HSPA13	146	P48723
LLLKLKEMAEAYLGM	HSPA13	151	P48723
EKLERRLLEELLKMF	INPP5F	156	Q9Y2H2
LLEYMRKLEARLEKV	CALCOCO1	496	Q9P1Z2
DEALLKRYRKEIMDL	CENPE	341	Q02224
DKLMAKALLLYGADI	POTEC	251	B2RU33
SRLYVGREKKLALML	MIA2	676	Q96PC5
EMDYFIKDKLLLERI	TMEM67	891	Q5HYA8
IKDKLLLERILGMEF	TMEM67	896	Q5HYA8
KKILLLKGFELMDDY	MNDA	6	P41218
DKLMAKALLLYGADI	POTED	251	Q86YR6
VLDEGKMKLDYILGL	RPS9	86	P46781
MFTDLKDGRKLLDLL	UTRN	56	P46939
GRYRLALLKAMELIE	SLFN14	826	P0C7P3
YLGELVRLILLKMAK	HKDC1	301	Q2TB90
KRGIIYRDLKLDNVM	PRKCA	456	P17252
IATMLKEILKGLDYL	STK26	121	Q9P289
IDLKLKDYGMDLIEV	PMS2P2	116	O95744
KDLEYLDLKMTGRDL	PLEKHA7	661	Q6IQ23
MELNEKRRGLKYELI	STRBP	516	Q96SI9
DKLMAKALLLYGADI	POTEI	251	P0CG38
KLLKLERIKDYLLME	PSMC1	61	P62191
KGIMAYSLEDLLLKV	CIDEC	56	Q96AQ7
LLRLLEEGEKIQHMY	WDFY3	2526	Q8IZQ1
TAMLYELIEKGKEIL	RNF25	111	Q96BH1
GEMNEKIKLLYRLHI	TBC1D8	911	O95759
EGDALKIMIYLIDKV	TBC1D30	356	Q9Y2I9
TDLYKDLRDGRMLIK	SPTB	76	P11277
ILRYSEGLEKLKDMK	TTC12	126	Q9H892
GHIIKDLYLLIMKDE	RAPGEFL1	241	Q9UHV5
DKLMAKALLLYGADI	POTEG	251	Q6S5H5
DKLMAKALLLYGADI	POTEM	251	A6NI47
ELGEYRQKLLMFLEI	VPS39	656	Q96JC1
LGMLQYKREDEAKLI	MYO5C	1361	Q9NQX4