Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	FLT1 FLT4 CSF1R ROS1 FGFR1 KIT	2.70e-06	65	121	6	GO:0004714
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	FLT1 FLT4 CSF1R ROS1 FGFR1 KIT	1.29e-05	85	121	6	GO:0019199
GeneOntologyMolecularFunction	protein tyrosine kinase activity	FLT1 FLT4 PTK2B CSF1R ROS1 FGFR1 KIT	2.92e-05	145	121	7	GO:0004713
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDC42BPG FLT1 PNKP FLT4 MAK LRRK2 CILK1 PTK2B TKFC CSF1R NEK5 ROS1 FGFR1 KIT	1.01e-04	709	121	14	GO:0016773
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	1.09e-04	3	121	2	GO:0018858
GeneOntologyMolecularFunction	melatonin receptor activity	GPR50 MTNR1A	2.17e-04	4	121	2	GO:0008502
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	2.17e-04	4	121	2	GO:0102391
GeneOntologyMolecularFunction	kinase activity	CDC42BPG FLT1 PNKP FLT4 MAK LRRK2 CILK1 PTK2B TKFC CSF1R NEK5 ROS1 FGFR1 KIT	2.19e-04	764	121	14	GO:0016301
GeneOntologyMolecularFunction	protein kinase activity	CDC42BPG FLT1 FLT4 MAK LRRK2 CILK1 PTK2B CSF1R NEK5 ROS1 FGFR1 KIT	2.89e-04	600	121	12	GO:0004672
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDC42BPG FLT1 PNKP FLT4 MAK LRRK2 CILK1 PARP14 PTK2B TKFC CSF1R NEK5 ROS1 FGFR1 KIT	5.51e-04	938	121	15	GO:0016772
GeneOntologyMolecularFunction	vascular endothelial growth factor receptor activity	FLT1 FLT4	7.50e-04	7	121	2	GO:0005021
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM2A ACSM2B	9.96e-04	8	121	2	GO:0004321
GeneOntologyBiologicalProcess	protein autophosphorylation	FLT1 FLT4 MAK LRRK2 PTK2B CSF1R ROS1 FGFR1 KIT	7.60e-06	228	120	9	GO:0046777
GeneOntologyBiologicalProcess	positive regulation of kinase activity	FLT1 FLT4 LRRK2 RGPD1 CHRNA3 AXIN2 PTK2B CSF1R ROS1 FGFR1 KIT	2.50e-05	405	120	11	GO:0033674
GeneOntologyBiologicalProcess	positive regulation of transferase activity	FLT1 PNKP FLT4 LRRK2 RGPD1 CHRNA3 AXIN2 PTK2B CSF1R ROS1 FGFR1 KIT	2.92e-05	490	120	12	GO:0051347
MousePheno	increased heart atrium size	TCF21 COX15 CMYA5 IRX4 FGFR1	1.16e-05	46	91	5	MP:0008725
MousePheno	abnormal heart atrium size	TCF21 COX15 CMYA5 IRX4 FGFR1	2.57e-05	54	91	5	MP:0031576
MousePheno	abnormal midface morphology	HOXB1 FGFR1 PAK1IP1 HCFC1	3.05e-05	28	91	4	MP:0030095
MousePheno	pigmentation phenotype	TFEC KIAA0319L LRRK2 CMYA5 RCC2 LIPH MITF SEL1L3 ARHGAP25 CTNNA1 UQCRFS1 CERS1 KIT HCFC1	4.78e-05	624	91	14	MP:0001186
MousePheno	abnormal tail morphology	TFEC VSTM2A LEPR AXIN2 CSF1R MITF KDM2B FGFR1 KIT HCFC1 DSE	5.95e-05	403	91	11	MP:0002111
Domain	Tyr_kinase_rcpt_3_CS	FLT1 FLT4 CSF1R KIT	1.08e-07	8	119	4	IPR001824
Domain	RECEPTOR_TYR_KIN_III	FLT1 FLT4 CSF1R KIT	1.08e-07	8	119	4	PS00240
Domain	DUF3371	TFEC TFE3 MITF	1.00e-06	4	119	3	PF11851
Domain	MiT/TFE_C	TFEC TFE3 MITF	1.00e-06	4	119	3	IPR021802
Domain	Tyr_kinase_cat_dom	FLT1 FLT4 PTK2B CSF1R ROS1 FGFR1 KIT	1.48e-06	88	119	7	IPR020635
Domain	TyrKc	FLT1 FLT4 PTK2B CSF1R ROS1 FGFR1 KIT	1.48e-06	88	119	7	SM00219
Domain	Ser-Thr/Tyr_kinase_cat_dom	FLT1 FLT4 PTK2B CSF1R NEK5 ROS1 FGFR1 KIT	2.85e-06	138	119	8	IPR001245
Domain	PROTEIN_KINASE_TYR	FLT1 FLT4 PTK2B CSF1R ROS1 FGFR1 KIT	2.85e-06	97	119	7	PS00109
Domain	Tyr_kinase_AS	FLT1 FLT4 PTK2B CSF1R ROS1 FGFR1 KIT	2.85e-06	97	119	7	IPR008266
Domain	Protein_kinase_ATP_BS	CDC42BPG FLT1 FLT4 MAK LRRK2 CILK1 PTK2B CSF1R NEK5 ROS1 FGFR1 KIT	5.53e-06	379	119	12	IPR017441
Domain	Pkinase_Tyr	FLT1 FLT4 PTK2B CSF1R ROS1 FGFR1 KIT	1.88e-05	129	119	7	PF07714
Domain	PROTEIN_KINASE_ATP	CDC42BPG FLT1 FLT4 MAK LRRK2 CILK1 PTK2B CSF1R NEK5 ROS1 FGFR1 KIT	3.70e-05	459	119	12	PS00107
Domain	FAM78	FAM78B FAM78A	4.03e-05	2	119	2	IPR029638
Domain	Prot_kinase_dom	CDC42BPG FLT1 FLT4 MAK LRRK2 CILK1 PTK2B CSF1R NEK5 ROS1 FGFR1 KIT	6.81e-05	489	119	12	IPR000719
Domain	PROTEIN_KINASE_DOM	CDC42BPG FLT1 FLT4 MAK LRRK2 CILK1 PTK2B CSF1R NEK5 ROS1 FGFR1 KIT	7.36e-05	493	119	12	PS50011
Domain	MITF_TFEB_C_3_N	TFE3 MITF	1.20e-04	3	119	2	PF15951
Domain	MiT/TFE_N	TFE3 MITF	1.20e-04	3	119	2	IPR031867
Domain	Melatonin_rcpt	GPR50 MTNR1A	1.20e-04	3	119	2	IPR000025
Domain	Kinase-like_dom	CDC42BPG FLT1 FLT4 MAK LRRK2 CILK1 PTK2B CSF1R NEK5 ROS1 FGFR1 KIT	1.79e-04	542	119	12	IPR011009
Domain	Tyr_kinase_CSF1/PDGF_rcpt	CSF1R KIT	5.94e-04	6	119	2	IPR016243
Domain	bHLH_dom	CDC42BPG TFEC TCF21 TFE3 MITF	9.52e-04	118	119	5	IPR011598
Domain	-	FLT1 FLT4 VSTM2A CMYA5 LEPR NEO1 CSF1R FCGRT ROS1 FGFR1 KIT HCFC1	1.08e-03	663	119	12	2.60.40.10
Domain	FN3	KIAA0319L CMYA5 LEPR NEO1 ROS1 HCFC1	1.20e-03	185	119	6	SM00060
Domain	Clathrin_mu	STON1 AP2M1	1.75e-03	10	119	2	IPR001392
Domain	Ig-like_fold	FLT1 FLT4 VSTM2A CMYA5 LEPR NEO1 CSF1R FCGRT ROS1 FGFR1 KIT HCFC1	1.83e-03	706	119	12	IPR013783
Domain	Adap_comp_sub	STON1 AP2M1	2.13e-03	11	119	2	PF00928
Domain	FN3_dom	KIAA0319L CMYA5 LEPR NEO1 ROS1 HCFC1	2.22e-03	209	119	6	IPR003961
Domain	Kelch_2	RABEPK HCFC1	3.00e-03	13	119	2	IPR011498
Domain	MHD	STON1 AP2M1	3.00e-03	13	119	2	PS51072
Domain	MHD	STON1 AP2M1	3.00e-03	13	119	2	IPR028565
Domain	Kelch_2	RABEPK HCFC1	3.00e-03	13	119	2	PF07646
Domain	-	KLHL6 RABEPK HCFC1	3.54e-03	48	119	3	2.120.10.80
Domain	IGc2	FLT1 FLT4 NEO1 CSF1R FGFR1 KIT	3.97e-03	235	119	6	SM00408
Domain	Ig_sub2	FLT1 FLT4 NEO1 CSF1R FGFR1 KIT	3.97e-03	235	119	6	IPR003598
Domain	IG_LIKE	FLT1 FLT4 VSTM2A LEPR NEO1 CSF1R FCGRT FGFR1 KIT	4.20e-03	491	119	9	PS50835
Domain	Ig-like_dom	FLT1 FLT4 VSTM2A LEPR NEO1 CSF1R FCGRT FGFR1 KIT	4.91e-03	503	119	9	IPR007110
Domain	AMP-bd_C	ACSM2A ACSM2B	5.14e-03	17	119	2	IPR025110
Domain	AMP-binding_C	ACSM2A ACSM2B	5.14e-03	17	119	2	PF13193
Domain	Kelch-typ_b-propeller	KLHL6 RABEPK HCFC1	5.20e-03	55	119	3	IPR015915
Domain	-	TFEC TCF21 TFE3 MITF	5.21e-03	109	119	4	4.10.280.10
Domain	HLH	TFEC TCF21 TFE3 MITF	5.56e-03	111	119	4	PF00010
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL	FLT1 FLT4 CSF1R FGFR1 KIT	4.55e-07	25	90	5	M47934
Pathway	WP_HIPPOMERLIN_SIGNALING_DYSREGULATION	FLT1 FLT4 CSF1R FGFR1 CTNNA1 KIT CDH16 CDH17	1.01e-06	121	90	8	M39823
Pathway	WP_HIPPO_SIGNALING_REGULATION	FLT1 FLT4 CSF1R FGFR1 KIT CDH16 CDH17	2.95e-06	98	90	7	M39830
Pathway	KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY	FLT1 FLT4 CSF1R FGFR1 KIT	1.86e-04	83	90	5	M47961
Pathway	KEGG_PATHWAYS_IN_CANCER	HSP90B1 BIRC3 AXIN2 CSF1R MITF FGFR1 CTNNA1 MMP2 KIT	2.26e-04	325	90	9	M12868
Pathway	KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY	FLT1 FLT4 CSF1R FGFR1 KIT	2.58e-04	89	90	5	M47963
Pathway	WP_IMATINIB_AND_CHRONIC_MYELOID_LEUKEMIA	FLT1 CSF1R KIT	2.65e-04	20	90	3	M39381
Pathway	KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY	FLT1 FLT4 CSF1R FGFR1 KIT	3.01e-04	92	90	5	M47927
Pathway	REACTOME_TRANSCRIPTIONAL_AND_POST_TRANSLATIONAL_REGULATION_OF_MITF_M_EXPRESSION_AND_ACTIVITY	TFEC TFE3 MITF KIT	3.09e-04	51	90	4	M48267
Pubmed	The protein tyrosine kinase family of the human genome.	FLT1 FLT4 PTK2B CSF1R ROS1 FGFR1 KIT	1.73e-08	83	121	7	11114734
Pubmed	The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.	TFEC TFE3 MITF	4.11e-08	3	121	3	11818452
Pubmed	Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.	FLT1 FLT4 CSF1R FGFR1 KIT	4.32e-08	28	121	5	18593464
Pubmed	Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.	TFEC TFE3 MITF	1.64e-07	4	121	3	11930005
Pubmed	Cloning and characterization of the murine genes for bHLH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily members.	TFEC TFE3 MITF	1.64e-07	4	121	3	10036191
Pubmed	The role of Axin2 in calvarial morphogenesis and craniosynostosis.	AXIN2 MKI67 FGFR1	4.09e-07	5	121	3	15790973
Pubmed	Secretion of MMP-2 and MMP-9 induced by VEGF autocrine loop correlates with clinical features in childhood acute lymphoblastic leukemia.	FLT1 FLT4 MMP2	4.09e-07	5	121	3	18829111
Pubmed	Fusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation.	FLT4 CTNNA1 KIT	2.27e-06	8	121	3	24567373
Pubmed	The bHLH-Zip transcription factor Tfeb is essential for placental vascularization.	FLT1 TFE3 MITF	2.27e-06	8	121	3	9806910
Pubmed	Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation.	NEO1 MITF MKI67	8.83e-06	12	121	3	31336386
Pubmed	Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.	FLT1 CYP21A2 LEPR MITF MMP2 ACBD3	1.05e-05	141	121	6	18636124
Pubmed	Cell type-specific deficiency of c-kit gene expression in mutant mice of mi/mi genotype.	MITF KIT	1.20e-05	2	121	2	7524330
Pubmed	KITD816V Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma.	MITF KIT	1.20e-05	2	121	2	28584020
Pubmed	The expression of MMP-2 and Ki-67 in head and neck melanoma, and their correlation with clinic-pathologic indices.	MKI67 MMP2	1.20e-05	2	121	2	25313763
Pubmed	Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.	FLT1 TCF21	1.20e-05	2	121	2	23063127
Pubmed	Allele-specific genetic interactions between Mitf and Kit affect melanocyte development.	MITF KIT	1.20e-05	2	121	2	20374522
Pubmed	Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis.	FLT4 FGFR1	1.20e-05	2	121	2	22761819
Pubmed	The naive airway hyperresponsiveness of the A/J mouse is Kit-mediated.	MITF KIT	1.20e-05	2	121	2	21768379
Pubmed	Mast cells in spotted mutant mice (W Ph mi).	MITF KIT	1.20e-05	2	121	2	6127714
Pubmed	Cardiovascular Effects of Renal Distal Tubule Deletion of the FGF Receptor 1 Gene.	LEPR FGFR1	1.20e-05	2	121	2	28993502
Pubmed	Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.	CSF1R KIT	1.20e-05	2	121	2	2456920
Pubmed	Differential effects of CSF-1R D802V and KIT D816V homologous mutations on receptor tertiary structure and allosteric communication.	CSF1R KIT	1.20e-05	2	121	2	24828813
Pubmed	Downregulation of c-Kit/MITF-M in graying hair of juvenile poliosis.	MITF KIT	1.20e-05	2	121	2	24287867
Pubmed	BALB/3T3 fibroblast-conditioned medium attracts cultured mast cells derived from W/W but not from mi/mi mutant mice, both of which are deficient in mast cells.	MITF KIT	1.20e-05	2	121	2	1382713
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	1.20e-05	2	121	2	29948332
Pubmed	Gastrointestinal stromal tumors caused by novel germline variants in SDHB and KIT: a report of two cases and literature review.	KIT SDHB	1.20e-05	2	121	2	35821557
Pubmed	Regional localization of the human c-ros-1 on 6q22 and flt on 13q12.	FLT1 ROS1	1.20e-05	2	121	2	3115921
Pubmed	Signaling and transcriptional regulation in the neural crest-derived melanocyte lineage: interactions between KIT and MITF.	MITF KIT	1.20e-05	2	121	2	11076759
Pubmed	Hypoxia and MITF regulate KIT oncogenic properties in melanocytes.	MITF KIT	1.20e-05	2	121	2	26973244
Pubmed	Molecular cloning of murine FLT and FLT4.	FLT1 FLT4	1.20e-05	2	121	2	8393164
Pubmed	KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation.	MITF KIT	1.20e-05	2	121	2	21273305
Pubmed	C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation.	MITF KIT	1.20e-05	2	121	2	21887372
Pubmed	Assessment of "grading" with Ki-67 and c-kit immunohistochemical expressions may be a helpful tool in management of patients with flat epithelial atypia (FEA) and columnar cell lesions (CCLs) on core breast biopsy.	MKI67 KIT	1.20e-05	2	121	2	19585492
Pubmed	The role of the tissue environment in the expression of spotting genes in the mouse.	MITF KIT	1.20e-05	2	121	2	4761674
Pubmed	The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor.	TFE3 MITF	1.20e-05	2	121	2	12039954
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	1.20e-05	2	121	2	19634011
Pubmed	Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.	TFE3 MITF	1.20e-05	2	121	2	16766266
Pubmed	Ubiquitin-specific protease 1 acts as an oncogene and promotes lenvatinib efficacy in hepatocellular carcinoma by stabilizing c-kit.	USP1 KIT	1.20e-05	2	121	2	35045360
Pubmed	TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells.	TFEC TFE3	1.20e-05	2	121	2	11467950
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	1.20e-05	2	121	2	16521160
Pubmed	Renal cell carcinoma with TFE3 translocation and succinate dehydrogenase B mutation.	TFE3 SDHB	1.20e-05	2	121	2	27910947
Pubmed	CDH17 alters MMP-2 expression via canonical NF-κB signalling in human gastric cancer.	MMP2 CDH17	1.20e-05	2	121	2	29783070
Pubmed	Activating mutation in the catalytic domain of c-kit elicits hematopoietic transformation by receptor self-association not at the ligand-induced dimerization site.	CSF1R KIT	1.20e-05	2	121	2	9949175
Pubmed	TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation.	TFEC TFE3	1.20e-05	2	121	2	8336698
Pubmed	Low c-kit expression of cultured mast cells of mi/mi genotype may be involved in their defective responses to fibroblasts that express the ligand for c-kit.	MITF KIT	1.20e-05	2	121	2	1381628
Pubmed	Roles of MITF for development of mast cells in mice: effects on both precursors and tissue environments.	MITF KIT	1.20e-05	2	121	2	15172970
Pubmed	Number of mast cells in the peritoneal cavity of mice: influence of microphthalmia transcription factor through transcription of newly found mast cell adhesion molecule, spermatogenic immunoglobulin superfamily.	MITF KIT	1.20e-05	2	121	2	15277223
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	RGPD1 AHNAK MKI67 FGFR1 HCFC1	1.30e-05	86	121	5	37253089
Pubmed	Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia.	FLT1 CSF1R KIT	1.45e-05	14	121	3	10981960
Pubmed	Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.	AXIN2 MITF CTNNA1	1.45e-05	14	121	3	33075808
Pubmed	Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.	PTK2B CSF1R KIT	1.81e-05	15	121	3	10679268
Pubmed	Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.	AXIN2 MITF CTNNA1	2.23e-05	16	121	3	19596317
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HSP90B1 DSG2 PPA1 RCC2 ESF1 KIAA1671 AP2M1 AHNAK MKI67 PRR14L ACBD3 HCFC1 RSBN1L	2.36e-05	934	121	13	33916271
Pubmed	Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development.	FLT1 FLT4 FGFR1	2.70e-05	17	121	3	16778080
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CDC42BPG HSP90B1 PNKP PPA1 RCC2 ESF1 AXIN2 AP2M1 MKI67 KDM2B CTNNA1 UQCRFS1 ACBD3 HCFC1 SDHB	2.95e-05	1247	121	15	27684187
Pubmed	Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.	TBX4 AXIN2 FGFR1 MMP2	3.32e-05	52	121	4	30389913
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FLT4 DSG2 LEPR NEO1 CSF1R FGFR1 KIT	3.42e-05	257	121	7	16335952
Pubmed	Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity.	MAK CILK1	3.59e-05	3	121	2	24244486
Pubmed	Vascular endothelial growth factor receptors 1,3 and caveolin-1 are implicated in colorectal cancer aggressiveness and prognosis--correlations with epidermal growth factor receptor, CD44v6, focal adhesion kinase, and c-Met.	FLT1 FLT4	3.59e-05	3	121	2	23580180
Pubmed	Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.	CSF1R KIT	3.59e-05	3	121	2	9027509
Pubmed	Immunohistochemical double stains against Ki67/MART1 and HMB45/MITF: promising diagnostic tools in melanocytic lesions.	MITF MKI67	3.59e-05	3	121	2	21610457
Pubmed	Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice.	MITF KIT	3.59e-05	3	121	2	8695840
Pubmed	A truncated derivative of FGFR1 kinase cooperates with FLT3 and KIT to transform hematopoietic stem cells in syndromic and de novo AML.	FGFR1 KIT	3.59e-05	3	121	2	35906694
Pubmed	The inhibition of tyrosine kinase receptor signalling in leiomyosarcoma cells using the small molecule kinase inhibitor PTK787/ZK222584 (Vatalanib®).	FLT1 FLT4	3.59e-05	3	121	2	25340839
Pubmed	Diverse epithelial cell populations contribute to the regeneration of secretory units in injured salivary glands.	AXIN2 KIT	3.59e-05	3	121	2	32994165
Pubmed	The antiangiogenic activity in xenograft models of brivanib, a dual inhibitor of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinases.	FLT1 FGFR1	3.59e-05	3	121	2	20103604
Pubmed	Specific expression of Gsta4 in mouse cochlear melanocytes: a novel role for hearing and melanocyte differentiation.	MITF KIT	3.59e-05	3	121	2	18983533
Pubmed	PARP14 correlates with GBM proliferation and poor prognosis by elevating expression of SAMD/SAMD9L.	PARP14 SAMD9L	3.59e-05	3	121	2	37612499
Pubmed	Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.	FLT1 PTK2B	3.59e-05	3	121	2	19718025
Pubmed	Single nucleotide polymorphisms in the angiogenic and lymphangiogenic pathways are associated with lymphedema caused by Wuchereria bancrofti.	FLT4 MMP2	3.59e-05	3	121	2	29122006
Pubmed	The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.	CSF1R KIT	3.59e-05	3	121	2	1710023
Pubmed	VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice.	FLT1 CSF1R	3.59e-05	3	121	2	16172397
Pubmed	CD117, Ki-67, and p53 predict survival in neuroendocrine carcinomas, but not within the subgroup of small cell lung carcinoma.	MKI67 KIT	3.59e-05	3	121	2	21058037
Pubmed	Signaling via vascular endothelial growth factor receptors.	FLT1 FLT4	3.59e-05	3	121	2	10579917
Pubmed	Impact of vascular endothelial growth factor receptor 1, 2, and 3 expression on the outcome of patients with gastric cancer.	FLT1 FLT4	3.59e-05	3	121	2	19068081
Pubmed	[Expressions of OB-R, IRF-1 and GR-β in airway smooth muscle cells of obese rats with asthma].	IRF1 LEPR	3.59e-05	3	121	2	23046934
Pubmed	Evaluation of PGP 9.5, NGFR, TGFβ1, FGFR1, MMP-2, AT2R2, SHH, and TUNEL in Primary Obstructive Megaureter Tissue.	FGFR1 MMP2	3.59e-05	3	121	2	34915763
Pubmed	All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells.	FLT1 FLT4	3.59e-05	3	121	2	14687619
Pubmed	MITF and TFEB cross-regulation in melanoma cells.	TFE3 MITF	3.59e-05	3	121	2	32881934
Pubmed	Contribution of the SgIGSF adhesion molecule to survival of cultured mast cells in vivo.	MITF KIT	3.59e-05	3	121	2	15158462
Pubmed	Expression of receptors for VEGFs on normal human thyroid follicular cells and their role in follicle formation.	FLT1 FLT4	3.59e-05	3	121	2	21751212
Pubmed	Adhesion G protein-coupled receptor G2 is dispensable for lumicrine signaling regulating epididymal initial segment differentiation and gene expression†.	ROS1 KIT	3.59e-05	3	121	2	37531264
Pubmed	Early endocardial morphogenesis requires Scl/Tal1.	FLT1 FLT4	3.59e-05	3	121	2	17722983
Pubmed	A prognostic index in skin melanoma through the combination of matrix metalloproteinase-2, Ki67, and p53.	MKI67 MMP2	3.59e-05	3	121	2	21334717
Pubmed	C-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3.	TFE3 MITF	3.59e-05	3	121	2	20214879
Pubmed	Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability.	LEPR FGFR1	3.59e-05	3	121	2	28813681
Pubmed	CD147 expression in pituitary adenomas and its significance for clinical outcome.	MKI67 MMP2	3.59e-05	3	121	2	20381119
Pubmed	The leptin receptor promoter controls expression of a second distinct protein.	LEPR KIT	3.59e-05	3	121	2	9207021
Pubmed	Fibroblast-dependent differentiation/proliferation of mast cells.	MITF KIT	3.59e-05	3	121	2	1764248
Pubmed	Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance.	FLT1 FLT4	3.59e-05	3	121	2	35050301
Pubmed	Explorative investigation of vascular endothelial growth factor receptor expression in primary ovarian cancer and its clinical relevance.	FLT1 FLT4	3.59e-05	3	121	2	24713547
Pubmed	Mitf regulates gene expression networks implicated in B cell homeostasis, germinal center responses, and tolerance.	TFE3 MITF	3.59e-05	3	121	2	38444862
Pubmed	Complete inhibition of goiter in mice requires combined gene therapy modification of angiopoietin, vascular endothelial growth factor, and fibroblast growth factor signaling.	FLT1 FGFR1	3.59e-05	3	121	2	15817662
Pubmed	Malignant hematopoietic cells induce an increased expression of VEGFR-1 and VEGFR-3 on bone marrow endothelial cells via AKT and mTOR signalling pathways.	FLT1 FLT4	3.59e-05	3	121	2	16959214
Pubmed	Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor.	MITF KIT	3.59e-05	3	121	2	9199364
Pubmed	Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells.	LEPR NEO1	3.59e-05	3	121	2	35704698
Pubmed	Whey peptides prevent chronic ultraviolet B radiation-induced skin aging in melanin-possessing male hairless mice.	MKI67 MMP2	3.59e-05	3	121	2	24174624
Pubmed	Prognostic roles of cross-talk between peritumoral hepatocytes and stromal cells in hepatocellular carcinoma involving peritumoral VEGF-C, VEGFR-1 and VEGFR-3.	FLT1 FLT4	3.59e-05	3	121	2	23737988
Pubmed	Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival.	FLT1 FLT4	3.59e-05	3	121	2	26394830
Pubmed	CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.	MAK CILK1	3.59e-05	3	121	2	23743448
Interaction	KIT interactions	HSP90B1 FLT1 FLT4 CSF1R FGFR1 USP1 KIT	9.93e-06	125	120	7	int:KIT
Interaction	PTPN11 interactions	HSP90B1 FLT1 FLT4 PPA1 LEPR PTK2B CSF1R ROS1 FGFR1 KIT USP47	1.27e-05	368	120	11	int:PTPN11
Interaction	DDX19A interactions	FLT1 FLT4 BIRC3 TRUB1 ROS1 FGFR1	1.43e-05	88	120	6	int:DDX19A
Cytoband	6q22	ROS1 DSE	1.91e-04	8	121	2	6q22
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	FLT1 FLT4 CSF1R ROS1 FGFR1 KIT	1.31e-08	40	74	6	321
GeneFamily	7D cadherins	CDH16 CDH17	1.65e-05	2	74	2	1187
GeneFamily	Immunoglobulin like domain containing	FLT1 FLT4 LEPR NEO1 CSF1R KIT	1.39e-04	193	74	6	594
GeneFamily	Basic helix-loop-helix proteins	TFEC TCF21 TFE3 MITF	1.08e-03	110	74	4	420
GeneFamily	Ubiquitin specific peptidases	USP43 USP1 USP47	1.56e-03	56	74	3	366
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	FLT1 FLT4 NEO1 FGFR1	4.30e-03	161	74	4	593
GeneFamily	Acyl-CoA synthetase family	ACSM2A ACSM2B	5.04e-03	26	74	2	40
Coexpression	GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN	CDC42BPG TWF2 CMYA5 PTK2B NEO1 COCH USP1 KIT DSE	3.43e-07	200	119	9	M327
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_70PLS_NONRESPONDER_2DY_DN	IRF1 RCC2 PNPLA6 CSF1R KDM2B CTNNA1 HCFC1	5.24e-06	148	119	7	M40921
Coexpression	WEST_ADRENOCORTICAL_TUMOR_DN	CTSF TCF21 CYP21A2 IRF1 ARMC9 LEPR HOXB1 AHNAK MTNR1A ARHGAP25 MMP2 USP47	7.44e-06	546	119	12	M3837
Coexpression	LIU_OVARIAN_CANCER_TUMORS_AND_XENOGRAFTS_KINASES_DN	FLT1 FLT4 LRRK2 CSF1R	1.32e-05	32	119	4	MM17
Coexpression	LIU_OVARIAN_CANCER_TUMORS_AND_XENOGRAFTS_KINASES_DN	FLT1 FLT4 LRRK2 CSF1R	1.69e-05	34	119	4	M45005
Coexpression	GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN	TFEC TWF2 PPA1 COCH AHNAK ARHGAP25 SDHB	3.35e-05	197	119	7	M4436
Coexpression	GSE17721_CTRL_VS_CPG_24H_BMDC_UP	COX6B2 GPR50 CILK1 EVI5 ERCC6L2 ACSM2A CDH17	3.69e-05	200	119	7	M3771
Coexpression	GSE20366_TREG_VS_TCONV_DN	DIPK1A TWF2 TRUB1 FAM78A GPBP1L1 PLCXD3 ESPL1	3.69e-05	200	119	7	M4312
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COX6B2 TBX4 TCF21 HOXB1 NEO1 MMP2 DSE	8.40e-07	188	121	7	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	KLHL6 TFEC LRRK2 PTK2B MITF SEL1L3 ARHGAP25	9.34e-07	191	121	7	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	droplet-Lung-21m-Mesenchymal\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAT8L COX6B2 TBX4 TCF21 NEO1 FGFR1 MMP2	9.34e-07	191	121	7	10a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FLT1 FLT4 BIRC3 FAM78A SEL1L3 KIT ACSM2B	1.00e-06	193	121	7	d338a7c0585b69947c37f44aa0381619493e31ea
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FLT1 FLT4 SRARP KIAA1671 SEL1L3 MKI67 KIT	1.00e-06	193	121	7	643f992dbce639e7d147924d8b8f455fcebf215a
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	KLHL6 TFEC LRRK2 PTK2B CSF1R MITF SEL1L3	1.07e-06	195	121	7	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFEC FLT1 SRARP SAMD9L FCGRT AHNAK	4.70e-06	158	121	6	ba9998cbf786c515d30fe42de02c7a246db1b6f9
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFEC FLT1 SRARP SAMD9L FCGRT AHNAK	4.70e-06	158	121	6	a2efcc184ef13d81373e3690253ba35f6be09c5f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFEC FLT1 SRARP SAMD9L FCGRT AHNAK	4.70e-06	158	121	6	e52eff2bd1e7e0ce9c278ed5109802865e0fe69c
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL6 FLT1 FLT4 SRARP FCGRT AHNAK	5.82e-06	164	121	6	6a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL6 FLT1 FLT4 SRARP FCGRT AHNAK	5.82e-06	164	121	6	ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL6 FLT1 FLT4 SRARP FCGRT AHNAK	6.24e-06	166	121	6	27af6c906cff1d40d134f0386db7708869691121
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COX6B2 FLT1 TCF21 FAM171A1 NEO1 KIT	8.43e-06	175	121	6	282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAT8L TFEC DSG2 SEL1L3 CDH16 CDH17	8.43e-06	175	121	6	6759d200a133034756de9cdf2d5daceca927aac9
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 STON1 ARHGAP23 FAM78B FAM171A1	1.05e-05	182	121	6	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX6B2 TFEC MAK CYP21A2 VSTM2A FCGRT	1.05e-05	182	121	6	3dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 STON1 ARHGAP23 FAM78B FAM171A1	1.05e-05	182	121	6	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	droplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFEC PPA1 RCC2 KDM2B PDIA5 KIT	1.09e-05	183	121	6	92ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCell	droplet-Marrow-nan-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFEC PPA1 RCC2 KDM2B PDIA5 KIT	1.09e-05	183	121	6	24db9cc717e651586317c6a8e03a3401651273c1
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT1 PARP14 LEPR KIAA1671 FAM171A1 KIT	1.23e-05	187	121	6	dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLT1 FLT4 KIAA1671 FAM78A SEL1L3 KIT	1.27e-05	188	121	6	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT1 FLT4 LEPR KIAA1671 FAM171A1 KIT	1.27e-05	188	121	6	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT1 FLT4 LEPR KIAA1671 FAM171A1 KIT	1.31e-05	189	121	6	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	droplet-Marrow-nan-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFEC DIPK1A LEPR CSF1R FCGRT AHNAK	1.35e-05	190	121	6	95d8dc8488e95158e84a44bb53ea4ab7bf3d44bb
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COX6B2 TBX4 TCF21 HOXB1 NEO1 MMP2	1.39e-05	191	121	6	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAT8L COX6B2 TCF21 NEO1 FGFR1 MMP2	1.39e-05	191	121	6	8a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TFEC PARP14 PJA2 AHNAK SEL1L3 ARHGAP25	1.47e-05	193	121	6	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FLT1 FLT4 LEPR KIAA1671 SEL1L3 KIT	1.47e-05	193	121	6	01c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDC42BPG DSG2 LRRK2 AXIN2 LIPH ROS1	1.47e-05	193	121	6	44839a606ae2f8e37421bda46d588189e1c943d2
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 ARHGAP23 FAM171A1 KIT DSE	1.51e-05	194	121	6	c8b9551b93a5aed62154b487db90130604a6125c
ToppCell	CF-Myeloid-cDC\|Myeloid / Disease state, Lineage and Cell class	DSG2 DIPK1A PPA1 RCC2 SEL1L3 KDM2B	1.51e-05	194	121	6	3feb8a0ba3368673c53e9cbd4980e73d18697718
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FLT1 FLT4 LEPR KIAA1671 SEL1L3 KIT	1.51e-05	194	121	6	53a5e8863d79a052dff0758f389be5ac3883c721
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CDC42BPG ARHGAP23 MAMLD1 RCC2 LIPH SEL1L3	1.51e-05	194	121	6	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	PND01-Mesenchymal-Mesenchymal_structural\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TBX4 TCF21 AXIN2 FGFR1 MMP2	1.56e-05	195	121	6	6bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCell	PND10-Mesenchymal-Mesenchymal_structural\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TCF21 FAM171A1 NEO1 FGFR1 MMP2	1.56e-05	195	121	6	11d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TBX4 TCF21 AXIN2 FGFR1 MMP2	1.56e-05	195	121	6	a3b468125e48f072255cede7645f6692298ecf54
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TCF21 FAM171A1 NEO1 FGFR1 MMP2	1.56e-05	195	121	6	1f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	FLT1 FLT4 ARHGAP23 KIAA1671 FAM171A1 FCGRT	1.56e-05	195	121	6	6b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TCF21 FAM171A1 NEO1 FGFR1 MMP2	1.56e-05	195	121	6	10f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BIRC3 LEPR PLCXD3 FGFR1 MMP2 DSE	1.61e-05	196	121	6	61bee32ca299219f31a30b57124e44e85b798e9f
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TBX4 TCF21 FAM171A1 NEO1 MMP2	1.61e-05	196	121	6	14246f00c90741a5f8683f377e22e3a7c99661b9
ToppCell	PND01-Mesenchymal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TBX4 TCF21 AXIN2 FGFR1 MMP2	1.65e-05	197	121	6	292b8cc3dafddf5d323fe4e3d3ea5ac61e6ce027
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 HSP90B1 RGPD1 BIRC3 PTK2B SEL1L3	1.65e-05	197	121	6	749e0e332644543cbdf2ee38c2b301ce0a019a7f
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	IRF1 PARP14 RCC2 SAMD9L AHNAK DSE	1.70e-05	198	121	6	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 NAT8L TFEC CSF1R MITF ARHGAP25	1.70e-05	198	121	6	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 HSP90B1 DIPK1A BIRC3 PTK2B SEL1L3	1.75e-05	199	121	6	1bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	CTSF IRF1 LEPR FCGRT AHNAK FGFR1	1.80e-05	200	121	6	6d8f6a6b3f61c529fbed1376659641030abf4f2c
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLT1 IRF1 PARP14 LEPR SAMD9L CTNNA1	1.80e-05	200	121	6	3585484c7e24e941708bee471ca607d8ccee74e6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LEPR SAMD9L COCH PDIA5 ROS1	3.28e-05	134	121	5	4ef5f395e321cf04e56560be2502a8aa157682f4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PARP14 LEPR SAMD9L CSF1R ZNF804B	5.61e-05	150	121	5	6c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCell	MS-CD4-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	CDC42BPG BIRC3 IRF1 PARP14 SAMD9L	5.98e-05	152	121	5	b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell	COVID-19_Mild-PLT_5\|World / Disease Group and Platelet Clusters	AXIN2 AHNAK FGFR1 CPLANE1 CDH17	5.98e-05	152	121	5	90ba4e8a735ec8921038fa072129535f0e3fd9ae
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAK TFE3 AXIN2 PDIA5 KIT	7.62e-05	160	121	5	19105debef96ea0c267d6a1d332303ec668ae47e
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL6 FLT1 FLT4 SRARP FCGRT	7.84e-05	161	121	5	a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	KIAA0319L EVI5 GPBP1L1 CSF1R AHNAK	8.08e-05	162	121	5	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 DIPK1A BIRC3 PTK2B SEL1L3	8.08e-05	162	121	5	8ed9149ff53b285591354057055d072b203a47c8
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL6 FLT1 FLT4 SRARP FCGRT	8.08e-05	162	121	5	0bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CMYA5 PTK2B AHNAK PLCXD3 ARHGAP25	8.08e-05	162	121	5	58da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 DIPK1A BIRC3 PTK2B SEL1L3	8.08e-05	162	121	5	7a05b05a33e1309fb5c0a8171db105ae68491815
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CMYA5 PTK2B AHNAK PLCXD3 ARHGAP25	8.08e-05	162	121	5	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL6 FLT1 FLT4 SRARP FCGRT	8.08e-05	162	121	5	5799a602ef8d83925907e8e34532428be7330228
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLT1 FLT4 MPC1L PDIA5 KIT	8.31e-05	163	121	5	d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C3orf62 FAM78B BCLAF3 CSF1R DSE	8.56e-05	164	121	5	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	STON1 DIPK1A KIAA1671 AHNAK DAAM2	9.32e-05	167	121	5	013971700e80b71e4b8c79b8fff0d8beeac295c3
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	TBX4 TCF21 CMYA5 NEO1 MMP2	9.59e-05	168	121	5	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	TBX4 TCF21 CMYA5 NEO1 MMP2	9.59e-05	168	121	5	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 MAMLD1 CDC16 CPLANE1 ACBD3	9.59e-05	168	121	5	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	facs-Kidney\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 TKFC GUCA2B CDH16 ACSM2B	9.59e-05	168	121	5	d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRUB1 GUCA2B DAAM2 CDH16 ACSM2B	9.86e-05	169	121	5	daed9083ee05c220365200328c2c50047fe21efd
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 ARHGAP23 FAM78B DAAM2 MMP2	9.86e-05	169	121	5	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAK SAMD9L CSF1R MKI67 ARHGAP25	1.04e-04	171	121	5	41932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L DIPK1A FAM78B LRRK2 AHNAK	1.07e-04	172	121	5	a125ac2db9c8ece95970a93aa6f7918d1dcef886
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L DIPK1A FAM78B LRRK2 AHNAK	1.07e-04	172	121	5	6aab59add5b180cee0ca31179c620e89d352d5c1
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 TBX4 ARHGAP23 FAM171A1	1.07e-04	172	121	5	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	Immune_cells-Monocytes\|Immune_cells / Lineage and Cell class	DIPK1A EVI5 CSF1R FCGRT AHNAK	1.10e-04	173	121	5	3eced40a65453a023a1673658592e7e2a099119b
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	LEPR TFE3 ZNF92 SEL1L3 PAK1IP1	1.13e-04	174	121	5	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L FLT1 FLT4 PARP14 LEPR	1.13e-04	174	121	5	fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L FLT1 FLT4 PARP14 LEPR	1.13e-04	174	121	5	1f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-ILC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	FLT1 ARMC9 TFE3 KIT ARMC8	1.13e-04	174	121	5	7c50bf9da37711266cc077eef4e54b58463f1d37
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L FLT1 FLT4 PARP14 LEPR	1.13e-04	174	121	5	ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCell	wk_20-22-Hematologic-Myeloid-CXCL9+_Mac\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TFEC LRRK2 IRF1 PARP14 CSF1R	1.16e-04	175	121	5	48f5bdbfc1ba40c3fb6411f12a69e61da2138296
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COX6B2 TCF21 PPA1 NEO1 MMP2	1.19e-04	176	121	5	d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 TBX4 ARHGAP23 FAM171A1	1.19e-04	176	121	5	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 TBX4 ARHGAP23 FAM171A1	1.19e-04	176	121	5	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 IRF1 PARP14 SAMD9L CTNNA1	1.22e-04	177	121	5	ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 IRF1 PARP14 SAMD9L CTNNA1	1.22e-04	177	121	5	f471f7747d6e8db7546899019af9508f48a14f89
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 IRF1 PARP14 SAMD9L CTNNA1	1.22e-04	177	121	5	cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DSG2 DIPK1A BIRC3 PPA1 KDM2B	1.22e-04	177	121	5	a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TFEC HSP90B1 MAK VSTM2A MKI67	1.22e-04	177	121	5	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	BAL-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	IRF1 PARP14 SAMD9L UQCRFS1 ESPL1	1.22e-04	177	121	5	aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	USP43 PTK2B ZNF804B PLCXD3 ROS1	1.29e-04	179	121	5	8766a5a066091879f521acfc612abf563ff78808
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 ZNF804B SEL1L3 ACSM2A ACSM2B	1.29e-04	179	121	5	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSG2 AXIN2 NEO1 GUCA2B CDH17	1.32e-04	180	121	5	7c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 STON1 ARHGAP23 DSE	1.39e-04	182	121	5	000ff26c51c6a1ea8770c02722523e55be83b46f
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTSF TCF21 CMYA5 MITF MMP2	1.39e-04	182	121	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	FLT1 FLT4 SRARP PLCXD3 MMP2	1.39e-04	182	121	5	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TBX4 RGPD1 PPCDC KDM2B FGFR1	1.39e-04	182	121	5	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	NS-moderate-d_07-13-Myeloid-Monocyte-derived_Macrophage\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TFEC FLT1 PARP14 SAMD9L CSF1R	1.39e-04	182	121	5	e03e995e5fd14fc6a7559b83c0ca4e7ccc8e3d0f
ToppCell	facs-Liver-Liver_non-hepato/SCs_st\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FLT4 STON1 ARHGAP23 DSE	1.39e-04	182	121	5	b906e6e584ecbe92d3030bbdc4426f244fbe0045
ToppCell	droplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFEC MAK VSTM2A LEPR TAT	1.43e-04	183	121	5	ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
Drug	Sunitinib	FLT1 FLT4 CSF1R KIT	4.56e-08	8	117	4	DB01268
Drug	AC1L1K22	FLT1 FLT4 PTK2B CSF1R MMP2 TAT	6.28e-08	41	117	6	CID000005305
Drug	ponatinib	FLT1 FLT4 PTK2B CSF1R FGFR1 KIT	1.37e-06	68	117	6	ctd:C545373
Drug	imetelstat	FLT1 FLT4 KIT	4.56e-06	7	117	3	ctd:C519562
Disease	renal cell carcinoma (is_marker_for)	FLT1 BIRC3 CSF1R FGFR1 CTNNA1 MMP2 KIT	9.71e-07	128	120	7	DOID:4450 (is_marker_for)
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	FLT1 FLT4 LRRK2 CILK1 TFE3 AHNAK MITF	2.57e-06	148	120	7	C0279702
Disease	gastrointestinal stromal tumor (is_implicated_in)	CSF1R KIT SDHB	1.06e-05	11	120	3	DOID:9253 (is_implicated_in)
Disease	X-21319 measurement	ACSM2A ACSM2B	1.64e-05	2	120	2	EFO_0800807
Disease	vascular dementia (biomarker_via_orthology)	FLT1 FGFR1 MMP2	2.31e-05	14	120	3	DOID:8725 (biomarker_via_orthology)
Disease	lysosomal storage disease (implicated_via_orthology)	TFEC TFE3 MITF	3.53e-05	16	120	3	DOID:3211 (implicated_via_orthology)
Disease	X-11478 measurement	ACSM2A ACSM2B	4.91e-05	3	120	2	EFO_0021242
Disease	Gastrointestinal stromal tumor	KIT SDHB	4.91e-05	3	120	2	cv:C0238198
Disease	GASTROINTESTINAL STROMAL TUMOR	KIT SDHB	4.91e-05	3	120	2	606764
Disease	Polydactyly	CILK1 PNPLA6 FGFR1 CPLANE1 ARMC8	1.19e-04	117	120	5	C0152427
Disease	carcinoma (implicated_via_orthology)	FLT1 FLT4 CSF1R KIT	1.37e-04	64	120	4	DOID:305 (implicated_via_orthology)
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	1.63e-04	5	120	2	EFO_0800378
Disease	Sarcomatoid Renal Cell Carcinoma	FLT1 LRRK2 TFE3 AHNAK MITF	1.82e-04	128	120	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	FLT1 LRRK2 TFE3 AHNAK MITF	1.82e-04	128	120	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	FLT1 LRRK2 TFE3 AHNAK MITF	1.82e-04	128	120	5	C1266044
Disease	Papillary Renal Cell Carcinoma	FLT1 LRRK2 TFE3 AHNAK MITF	1.82e-04	128	120	5	C1306837
Disease	Renal Cell Carcinoma	FLT1 LRRK2 TFE3 AHNAK MITF	1.82e-04	128	120	5	C0007134
Disease	leiomyosarcoma (is_marker_for)	FLT1 KIT	2.43e-04	6	120	2	DOID:1967 (is_marker_for)
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	2.43e-04	6	120	2	EFO_0800106
Disease	lung non-small cell carcinoma (is_implicated_in)	BIRC3 IRF1 CHRNA3 CSF1R FGFR1	2.66e-04	139	120	5	DOID:3908 (is_implicated_in)
Disease	melanoma (is_marker_for)	FLT1 MITF KIT	3.27e-04	33	120	3	DOID:1909 (is_marker_for)
Disease	lung adenocarcinoma (is_marker_for)	HSP90B1 CHRNA3 CSF1R MKI67	4.09e-04	85	120	4	DOID:3910 (is_marker_for)
Disease	fibrinogen measurement, coronary artery disease	FLT1 CYP21A2 IRF1 RPH3A LEPR	4.27e-04	154	120	5	EFO_0001645, EFO_0004623
Disease	systemic lupus erythematosus	STON1 CYP21A2 PPCDC IRF1 ARMC9 EVI5 FAM171A1 GUCA2B ZNF804B KIT DSE	4.28e-04	799	120	11	MONDO_0007915
Disease	mitochondrial encephalomyopathy (implicated_via_orthology)	COX6B2 SDHB	4.52e-04	8	120	2	DOID:890 (implicated_via_orthology)
Disease	glycosyl-N-(2-hydroxynervonoyl)-sphingosine (d18:1/24:1(2OH)) measurement	CYP21A2 RGPD1	4.52e-04	8	120	2	EFO_0800533
Disease	neutrophil count	ARHGAP23 DIPK1A FAM78B CYP21A2 PPCDC IRF1 PIGV LEPR EVI5 ZNF92 MITF ARHGAP25 KIT ACBD3 USP47	4.96e-04	1382	120	15	EFO_0004833
Disease	platelet crit	TFEC STON1 DIPK1A CYP21A2 LRRK2 IRF1 LEPR FCGRT MITF PDIA5 ARHGAP25 KIT	5.14e-04	952	120	12	EFO_0007985
Disease	cervix uteri carcinoma in situ (is_marker_for)	CSF1R CTNNA1 MMP2	6.71e-04	42	120	3	DOID:8991 (is_marker_for)
Disease	interventricular septum thickness	MITF KDM2B	7.23e-04	10	120	2	EFO_0009287
Disease	fibrinogen measurement, tissue plasminogen activator measurement	CYP21A2 IRF1 LEPR	8.22e-04	45	120	3	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	CYP21A2 IRF1 LEPR	8.22e-04	45	120	3	EFO_0004623, EFO_0004792
Disease	Gastrointestinal Stromal Sarcoma	CTNNA1 KIT SDHB	9.33e-04	47	120	3	C3179349
Disease	fibrinogen measurement	CYP21A2 IRF1 LEPR PDIA5	1.04e-03	109	120	4	EFO_0004623
Disease	Oligodontia	AXIN2 FGFR1	1.05e-03	12	120	2	C4082304
Disease	thyroid gland carcinoma (is_marker_for)	FLT1 FLT4	1.05e-03	12	120	2	DOID:3963 (is_marker_for)
Disease	Gastrointestinal Stromal Tumors	CTNNA1 KIT SDHB	1.12e-03	50	120	3	C0238198
Disease	Diabetic Neuralgia	LEPR MMP2	1.45e-03	14	120	2	C0751074
Disease	Diabetic Neuropathies	LEPR MMP2	1.45e-03	14	120	2	C0011882
Disease	Asymmetric Diabetic Proximal Motor Neuropathy	LEPR MMP2	1.45e-03	14	120	2	C0271674
Disease	Symmetric Diabetic Proximal Motor Neuropathy	LEPR MMP2	1.45e-03	14	120	2	C0271673
Disease	Diabetic Mononeuropathy	LEPR MMP2	1.45e-03	14	120	2	C0271678
Disease	Diabetic Autonomic Neuropathy	LEPR MMP2	1.45e-03	14	120	2	C0271686
Disease	Diabetic Amyotrophy	LEPR MMP2	1.45e-03	14	120	2	C0271685
Disease	Diabetic Polyneuropathies	LEPR MMP2	1.45e-03	14	120	2	C0271680
Disease	Hypodontia	AXIN2 FGFR1	1.45e-03	14	120	2	C0020608
Disease	Diabetic Asymmetric Polyneuropathy	LEPR MMP2	1.45e-03	14	120	2	C0393835
Disease	Testicular Germ Cell Tumor	MMP2 KIT	1.45e-03	14	120	2	C1336708
Disease	Ischemic stroke, fibrinogen measurement	CYP21A2 IRF1 LEPR	1.48e-03	55	120	3	EFO_0004623, HP_0002140
Disease	electrocardiography	RPGRIP1 STON1 SRARP ARMC9 IRX4 ROS1 FGFR1 CDH17	1.49e-03	530	120	8	EFO_0004327
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	CYP21A2 IRF1 LEPR	1.55e-03	56	120	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	quinate measurement	LRRK2 LEPR	1.66e-03	15	120	2	EFO_0021167
Disease	fibrinogen measurement, factor VII measurement	CYP21A2 IRF1 LEPR	1.72e-03	58	120	3	EFO_0004619, EFO_0004623
Disease	Malignant neoplasm of skin	FLT1 PTK2B KIT	1.81e-03	59	120	3	C0007114
Disease	Skin Neoplasms	FLT1 PTK2B KIT	1.81e-03	59	120	3	C0037286
Disease	lung small cell carcinoma (is_marker_for)	CHRNA3 CSF1R	1.90e-03	16	120	2	DOID:5409 (is_marker_for)
Disease	Benign neoplasm of stomach	IRF1 AXIN2	2.14e-03	17	120	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	IRF1 AXIN2	2.14e-03	17	120	2	C0496905
Disease	Carcinoma in situ of stomach	IRF1 AXIN2	2.14e-03	17	120	2	C0154060
Disease	cholangiocarcinoma (is_marker_for)	MKI67 MMP2 KIT	2.28e-03	64	120	3	DOID:4947 (is_marker_for)
Disease	total blood protein measurement	STON1 DIPK1A CYP21A2 PPCDC CSF1R FCGRT FGFR1	2.46e-03	449	120	7	EFO_0004536
Disease	apolipoprotein A 1 measurement	STON1 CYP21A2 PPCDC LEPR PJA2 GUCA2B USP1 KIT CDH16 CDH17	2.47e-03	848	120	10	EFO_0004614
Disease	venous thromboembolism, fibrinogen measurement	CYP21A2 IRF1 LEPR	2.60e-03	67	120	3	EFO_0004286, EFO_0004623
Disease	renal cell carcinoma (is_implicated_in)	TFE3 CSF1R KIT	2.83e-03	69	120	3	DOID:4450 (is_implicated_in)
Disease	quinolinic acid measurement	CYP21A2 ZNF804B	3.27e-03	21	120	2	EFO_0010528
Disease	Joubert syndrome 1	ARMC9 CPLANE1	3.27e-03	21	120	2	C4551568
Disease	Infiltrating duct carcinoma of female breast	MAK FGFR1	3.27e-03	21	120	2	C3165106
Disease	Stomach Carcinoma	IRF1 AXIN2	3.27e-03	21	120	2	C0699791
Disease	lung cancer (is_implicated_in)	CHRNA3 AXIN2 CSF1R	3.45e-03	74	120	3	DOID:1324 (is_implicated_in)
Disease	melanoma	FLT1 PTK2B MITF ROS1 KIT	3.51e-03	248	120	5	C0025202
Disease	dilated cardiomyopathy (biomarker_via_orthology)	DSG2 AXIN2	3.59e-03	22	120	2	DOID:12930 (biomarker_via_orthology)
Disease	Craniofacial Abnormalities	B4GALT7 HOXB1 FGFR1 MMP2	3.84e-03	156	120	4	C0376634
Disease	prostate cancer (is_marker_for)	PTK2B FGFR1 CTNNA1 MMP2	3.84e-03	156	120	4	DOID:10283 (is_marker_for)
Disease	Disproportionate short stature	SMARCAL1 CILK1 FGFR1	3.85e-03	77	120	3	C0878659
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	MITF SDHB	3.92e-03	23	120	2	C1708353
Disease	insulin sensitivity measurement	CYP21A2 ARMC8	3.92e-03	23	120	2	EFO_0004471

Protein segments in the cluster

Peptide	Gene	Start	Entry
AEFMRVPAQKIWKPD	CHRNA3	106	P32297
DMEKAGKRLPSPALW	ACSM2A	56	Q08AH3
KPNANDAQVLMWRPK	FAM78B	236	Q5VT40
LMLDNWKRGDSPTEK	BIRC3	71	Q13489
QWMLESERQSKPKPH	AXIN2	621	Q9Y2T1
DVEAHGPEWNLKMPK	AHNAK	616	Q09666
DVDVQGPDWHLKMPK	AHNAK	4176	Q09666
KKMDPGFPKLIADAW	MMP2	596	P08253
MPRKKAAAAAWEEPS	RCC2	1	Q9P258
SDMKWQKLNPTGAAP	RABEPK	226	Q7Z6M1
EPDPKTWKANFRCAM	IRF1	71	P10914
MTWPPRNKCADEKRP	IRX4	206	P78413
DADPMKRKPWTSLSS	CDC42BPG	1501	Q6DT37
FSVIDKPPGMAEKWK	DSG2	531	Q14126
REAMFALPPEKKWQI	DAAM2	66	Q86T65
PSKAPMKKENQWFDV	HCFC1	1801	P51610
PWADKVKVPDMAEIQ	PNPLA6	1186	Q8IY17
DKKSPWQKREERPLM	FAM171A1	871	Q5VUB5
PSTNKWSLKAAMPVE	KLHL6	491	Q8WZ60
WSVRPSDMAKKTFNP	TAT	41	P17735
SWLGRDPPDMTKLKK	KIAA1671	656	Q9BY89
KGNARLPVKWMAPES	KIT	826	P10721
DIMKTCWDADPLKRP	KIT	901	P10721
WGLPLAAFKDMKASP	MPC1L	36	P0DKB6
MLDVEAQEPPKGKWS	COX6B2	1	Q6YFQ2
PSKPNAWKANRMEHK	GPBP1L1	246	Q9HC44
MEKRLGVKPNPASWI	KIAA0319L	1	Q8IZA0
EMLDWNPPKAKASVL	ARMC9	771	Q7Z3E5
AVSPKEMAGKIPNWL	GPR50	261	Q13585
MFPSRRKAAQLPWED	B4GALT7	1	Q9UBV7
MVKKWADFAGRPEPL	CYP21A2	81	P08686
VAKDPRFWEMPEKDR	ESF1	16	Q9H501
FPRTPQEKMQEAWKE	FAM90A27P	121	A6NNH2
NLEWKEPPSMRLKAR	FCGRT	196	P55899
WRPPAGAQKARSIKM	NEK5	331	Q6P3R8
TTGRWKDPPKKNAMN	EVI5	546	O60447
LSKGQAEVDAMKPWL	LRRK2	1421	Q5S007
ERMAAQPSWLVKDAP	DSE	131	Q9UL01
RMKKLFWEDVPNPKN	LEPR	866	P48357
APSMWTRPQIKDFKE	ACBD3	371	Q9H3P7
NWKDHLRGKDPPMTK	LIPH	301	Q8WWY8
NDKKKWARPPISMNF	AP2M1	376	Q96CW1
LDPAARVTGMKKWPR	MKI67	1076	P46013
NWKKELANSPDCPQM	PITPNB	176	P48739
NPIKVDPTMWDTIKN	PARP14	401	Q460N5
MNDIKPIWQRPSKEV	HSP90B1	336	P14625
TMKTLKNIISPPWDF	CDC16	551	Q13042
AVWKPLMKVLQNAPD	ARMC8	426	Q8IUR7
VKGNARLPVKWMAPE	CSF1R	811	P07333
TARTFDWMKVKRNPP	HOXB1	176	P14653
DKDLQKLPWESMPSL	ESPL1	1896	Q14674
SWKNAEDRMALANKP	KDM2B	871	Q8NHM5
KDPKRPVAWRMDSEK	BCLAF3	41	A2AJT9
SLNLPAVSWKMKAPE	CTNNA1	851	P35221
NLKLSSEMSEKPWSP	CPLANE1	2581	Q9H799
KTTNGRLPVKWMAPE	FGFR1	656	P11362
PFKEEAWALLMDKSP	C3orf62	211	Q6ZUJ4
AWALLMDKSPQKATD	C3orf62	216	Q6ZUJ4
FISPKDENWMLGKPE	CMYA5	1886	Q8N3K9
MKKLSDLEAQWAPSP	GUCA2B	41	Q16661
MKQAKSVGDLAPPEW	CTSF	261	Q9UBX1
LQPRDAAKMPESAWK	CERS1	91	P27544
PKRWDMLTEPDGQEK	CAPRIN2	401	Q6IMN6
MTEMLNWDPKKRPTA	MAK	261	P20794
PRKLQESGKKPSWME	MAMLD1	26	Q13495
PRWSNAKMEIATKDP	PPA1	51	Q15181
MKTKNPDSQWPPRAA	ANKS3	391	Q6ZW76
DWHLIKEMKPPTSQE	COX15	101	Q7KZN9
SGPMEKAKQRPKDFW	ERCC6L2	1476	Q5T890
KASVTRLPIKWMSPE	PTK2B	581	Q14289
ENIWKAPKPVEMVEN	CDH17	236	Q12864
NRNEWKRKSDPLPMM	C4orf54	1271	D6RIA3
VAWAPLDDLKDMASK	COCH	501	O43405
SMDQLFTPSWPRKAK	DIPK1A	256	Q5T7M9
THWTMSRKKDPDQPA	CDH16	806	O75309
TKKKFLEWMQNPEAP	PDIA5	371	Q14554
ASGWDKRPNSKPMAL	PRR14L	1676	Q5THK1
PPRWAEDQNSLRKMI	RGPD1	791	P0DJD0
KLQSRKDSDDGPIMW	RSBN1L	506	Q6PCB5
PSMCRAFPWEKELKD	SEL1L3	491	Q68CR1
SDPFVKLWLKPDMGK	RPH3A	586	Q9Y2J0
PEKMWPKDENFEQRS	RPGRIP1	241	Q96KN7
MAPSEDPRDWRANLK	SRARP	1	Q8NEQ6
KPNANDAQVLMWRPK	FAM78A	256	Q5JUQ0
TALDWARQAKMKAPK	SAMD9L	1101	Q8IVG5
LANKKQSAMPWDQDP	NANOGNB	31	Q7Z5D8
PTPTIKWMKNEEALD	NEO1	276	Q92859
SFQAKGIWKKPEEMP	SMARCAL1	91	Q9NZC9
PKKRMRKSNPGWENL	PNKP	136	Q96T60
DMEKAGKRLPSPALW	ACSM2B	56	Q68CK6
LRDMLQWDPKKRPTA	CILK1	261	Q9UPZ9
AWDRSKPLLFCPAMN	PPCDC	126	Q96CD2
MWPQDPSRKEVLRFA	PIGV	1	Q9NUD9
GKNELKLADWMATLP	PLCXD3	6	Q63HM9
DSMKNWAPQVPKDLP	URGCP	101	Q8TCY9
HEKPARPEGQKAMNW	USP43	941	Q70EL4
EPWNLKRHEMVDKTP	ZNF92	61	Q03936
EASPMWLQDMKPRKN	VSTM2A	161	Q8TAG5
PKTMIANPDWEKFQR	ZNF804B	536	A4D1E1
LSDIPEGKNMAFKWR	UQCRFS1	156	P47985
TLIPKSNDPDMRWNK	MITF	336	O75030
TLIPKSSDPEMRWNK	TFE3	371	P19532
QPKSGWSFMLRIPEK	STON1	271	Q9Y6Q2
SWAPKKEPYAREMLA	ARHGAP23	1151	Q9P227
SSKVPREKPGDWKMQ	ARHGAP25	421	P42331
KMAPKLIWPESQSLL	ZNF75CP	191	Q92670
KGSARLPLKWMAPES	FLT4	1071	P35916
RWKPSEMKLDPFQEV	USP47	1231	Q96K76
TWPFMVAGKPESDLK	TCF21	151	O43680
PFIMAVKEDGLWSKP	ROS1	676	P08922
VWLDKVADMKESLPP	PAK1IP1	301	Q9NWT1
VSLWSPAMKEPLAKI	WDR46	341	O15213
YNKRPLPATSWEDMK	ZCCHC9	11	Q8N567
EAGMPSPEWTKRKKQ	TRUB1	96	Q8WWH5
IPKSNDPDMRWNKGT	TFEC	166	O14948
DPDMRWNKGTILKAS	TFEC	171	O14948
DNKWMVAGKAEPAMP	TBX4	131	P57082
RWDPDKAGDKPHMQT	SDHB	46	P21912
PLKAKTSLPAWSAAM	TKFC	461	Q3LXA3
KGDTRLPLKWMAPES	FLT1	1056	P17948
AMDQESGKAVWPKPA	PJA2	11	O43164
LAWSPDNSPVRLKML	TWF2	86	Q6IBS0
PEPKTEMKTLRWAIS	USP1	476	O94782
DVADRVKWKPSPLMT	MTNR1A	326	P48039
AKKDALLAAAGAMWP	NAT8L	26	Q8N9F0