Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	TSP_1	THBS2 HMCN1 ADAMTS18	7.18e-04	63	52	3	PF00090
Domain	EGF-like_CS	HHIP THBS2 HMCN1 LTBP4 EPHA10	7.80e-04	261	52	5	IPR013032
Domain	TSP1	THBS2 HMCN1 ADAMTS18	7.87e-04	65	52	3	SM00209
Domain	TSP1_rpt	THBS2 HMCN1 ADAMTS18	7.87e-04	65	52	3	IPR000884
Domain	TSP1	THBS2 HMCN1 ADAMTS18	7.87e-04	65	52	3	PS50092
Domain	EGF_2	HHIP THBS2 HMCN1 LTBP4 EPHA10	8.35e-04	265	52	5	PS01186
Domain	EGF_CA	THBS2 HMCN1 LTBP4	1.77e-03	86	52	3	PF07645
Domain	TSPN	THBS2 COL5A3	1.85e-03	23	52	2	SM00210
Domain	FHA	FOXK2 KIF1B	2.74e-03	28	52	2	SM00240
Domain	VWC	THBS2 CHRD	2.74e-03	28	52	2	PF00093
Domain	FHA_DOMAIN	FOXK2 KIF1B	3.36e-03	31	52	2	PS50006
Domain	FHA	FOXK2 KIF1B	3.36e-03	31	52	2	PF00498
Domain	EGF_3	HHIP THBS2 HMCN1 LTBP4	4.12e-03	235	52	4	PS50026
Domain	EGF	HHIP THBS2 HMCN1 LTBP4	4.12e-03	235	52	4	SM00181
Domain	FHA_dom	FOXK2 KIF1B	4.51e-03	36	52	2	IPR000253
Domain	VWFC_1	THBS2 CHRD	4.51e-03	36	52	2	PS01208
Domain	-	FOXK2 KIF1B	4.51e-03	36	52	2	2.60.200.20
Domain	EGF_CA	THBS2 HMCN1 LTBP4	4.76e-03	122	52	3	SM00179
Domain	EGF-like_Ca-bd_dom	THBS2 HMCN1 LTBP4	4.98e-03	124	52	3	IPR001881
Domain	VWC	THBS2 CHRD	5.01e-03	38	52	2	SM00214
Domain	VWFC_2	THBS2 CHRD	5.01e-03	38	52	2	PS50184
Domain	EGF-like_dom	HHIP THBS2 HMCN1 LTBP4	5.06e-03	249	52	4	IPR000742
Domain	EGF_1	HHIP THBS2 HMCN1 LTBP4	5.50e-03	255	52	4	PS00022
Domain	VWF_dom	THBS2 CHRD	6.10e-03	42	52	2	IPR001007
Domain	FERM_M	FRMD7 FRMD8	7.28e-03	46	52	2	PF00373
Domain	CUB	LRP3 CSMD3	8.22e-03	49	52	2	PF00431
Domain	-	FRMD7 FRMD8	8.22e-03	49	52	2	1.20.80.10
Domain	FERM_central	FRMD7 FRMD8	8.22e-03	49	52	2	IPR019748
Domain	FERM_domain	FRMD7 FRMD8	8.22e-03	49	52	2	IPR000299
Domain	FERM_1	FRMD7 FRMD8	8.55e-03	50	52	2	PS00660
Domain	FERM_2	FRMD7 FRMD8	8.55e-03	50	52	2	PS00661
Domain	FERM_3	FRMD7 FRMD8	8.55e-03	50	52	2	PS50057
Domain	Band_41_domain	FRMD7 FRMD8	8.55e-03	50	52	2	IPR019749
Domain	CUB	LRP3 CSMD3	8.55e-03	50	52	2	SM00042
Pubmed	Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration.	GLI3 EPHA10	2.73e-06	2	58	2	33990369
Pubmed	Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2.	THBS2 NOS3	2.73e-06	2	58	2	21949402
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	EOMES THBS2 HMCN1 ADAMTS18	7.75e-06	75	58	4	20637190
Pubmed	Effect modification by delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase gene polymorphisms on associations between patella lead and renal function in lead workers.	ALAD NOS3	8.19e-06	3	58	2	16487505
Pubmed	Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation.	EEF1AKMT4-ECE2 EEF1AKMT4	8.19e-06	3	58	2	28520920
Pubmed	Associations of uric acid with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers.	ALAD NOS3	8.19e-06	3	58	2	16263504
Pubmed	Associations of patella lead with polymorphisms in the vitamin D receptor, delta-aminolevulinic acid dehydratase and endothelial nitric oxide synthase genes.	ALAD NOS3	8.19e-06	3	58	2	15213514
Pubmed	Associations of renal function with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers.	ALAD NOS3	8.19e-06	3	58	2	14527840
Pubmed	Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development.	EOMES DLGAP4	1.64e-05	4	58	2	35585091
Pubmed	Counter-Balance Between Gli3 and miR-7 Is Required for Proper Morphogenesis and Size Control of the Mouse Brain.	EOMES GLI3	4.08e-05	6	58	2	30210296
Pubmed	TMEM216 promotes primary ciliogenesis and Hedgehog signaling through the SUFU-GLI2/GLI3 axis.	HHIP GLI3	5.71e-05	7	58	2	38261656
Pubmed	3D Mapping Reveals a Complex and Transient Interstitial Matrix During Murine Kidney Development.	FREM2 COL5A3	7.60e-05	8	58	2	33875569
Pubmed	Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.	FREM2 HHIP THBS2 GLI3	9.01e-05	140	58	4	26930384
Pubmed	Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis.	HHIP GLI3	9.77e-05	9	58	2	38848388
Pubmed	Exocrine glands and the Chievitz organ of some mouse mutants.	FREM2 GLI3	9.77e-05	9	58	2	5088022
Pubmed	Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors.	EOMES GLI3	9.77e-05	9	58	2	28781964
Pubmed	Follistatin interacts with Noggin in the development of the axial skeleton.	UNCX CHRD	1.22e-04	10	58	2	24514266
Pubmed	Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice.	UNCX GLI3	1.22e-04	10	58	2	35977544
Pubmed	FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.	EOMES CYP46A1	1.22e-04	10	58	2	25402856
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	FREM2 COL5A3	1.22e-04	10	58	2	15345741
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	OBSL1 NAA30 CTU1 FAM83H IWS1	1.46e-04	300	58	5	28561026
Pubmed	Gli3 is required for maintenance and fate specification of cortical progenitors.	EOMES GLI3	1.49e-04	11	58	2	21525285
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FREM2 HMCN1 COL5A3 LTBP4	1.78e-04	167	58	4	22159717
Pubmed	A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells.	ABCB10 ALAD	1.78e-04	12	58	2	20508144
Pubmed	Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte.	HHIP GLI3	1.78e-04	12	58	2	10981962
Pubmed	Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina.	HHIP GLI3	1.78e-04	12	58	2	18417110
Pubmed	SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer.	GLI3 RXRB	1.78e-04	12	58	2	31911863
Pubmed	Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression.	EOMES GLI3	1.78e-04	12	58	2	30093555
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FOXK2 TNKS1BP1 POLR1G CTU1 GOLGA2 IWS1	1.90e-04	503	58	6	16964243
Pubmed	Expression patterns of Hedgehog signalling pathway members during mouse palate development.	HHIP GLI3	2.11e-04	13	58	2	16168717
Pubmed	Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.	HHIP GLI3	2.11e-04	13	58	2	25448692
Pubmed	Analysis of transcription factors expressed at the anterior mouse limb bud.	EOMES GLI3	2.11e-04	13	58	2	28467430
Pubmed	Gli2 influences proliferation in the developing lung through regulation of cyclin expression.	HHIP GLI3	2.11e-04	13	58	2	19574535
Pubmed	FOXD1 is required for 3D patterning of the kidney interstitial matrix.	FREM2 COL5A3	2.11e-04	13	58	2	36335435
Pubmed	Formal proof of the requirement of MESP1 and MESP2 in mesoderm specification and their transcriptional control via specific enhancers in mice.	EOMES UNCX	2.11e-04	13	58	2	34679163
Pubmed	BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period.	EOMES GLI3	2.46e-04	14	58	2	37300483
Pubmed	Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis.	EOMES UNCX	2.46e-04	14	58	2	26728556
Pubmed	Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning.	GLI3 CHRD	2.46e-04	14	58	2	23313125
Pubmed	Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.	HHIP GLI3	2.46e-04	14	58	2	24076664
Pubmed	Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development.	EOMES UNCX	3.23e-04	16	58	2	24633704
Pubmed	A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex.	EOMES GLI3	3.23e-04	16	58	2	38713624
Pubmed	A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers.	HHIP GLI3	3.23e-04	16	58	2	24726283
Pubmed	Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice.	HHIP GLI3	3.66e-04	17	58	2	22402963
Pubmed	Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3.	EOMES GLI3	3.66e-04	17	58	2	16957084
Pubmed	Spatiotemporal regulation of GLI target genes in the mammalian limb bud.	EOMES HHIP GLI3 FRMD8	4.02e-04	207	58	4	26238476
Pubmed	Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract.	EOMES GLI3	4.11e-04	18	58	2	26509897
Pubmed	Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.	UNCX GOLGA2	4.59e-04	19	58	2	17664336
Pubmed	Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog.	EOMES GLI3	4.59e-04	19	58	2	32234482
Pubmed	Cooperative activity of noggin and gremlin 1 in axial skeleton development.	UNCX GLI3	4.59e-04	19	58	2	21303853
Pubmed	Specific requirement of Gli transcription factors in Hedgehog-mediated intestinal development.	HHIP GLI3	4.59e-04	19	58	2	23645682
Pubmed	APC sets the Wnt tone necessary for cerebral cortical progenitor development.	EOMES GLI3	4.59e-04	19	58	2	28916710
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FOXK2 IER5L LRP3 FRMD8 TNKS1BP1 FBXL19 LTBP4 FAM83H	4.74e-04	1105	58	8	35748872
Pubmed	The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis.	EOMES GLI3	5.09e-04	20	58	2	35931079
Pubmed	Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning.	EOMES GLI3	5.09e-04	20	58	2	30843579
Pubmed	The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice.	EOMES GLI3	5.62e-04	21	58	2	20081193
Pubmed	Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model.	HHIP GLI3	5.62e-04	21	58	2	28688895
Pubmed	Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome.	UNCX GLI3	5.62e-04	21	58	2	14745966
Pubmed	Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development.	HHIP GLI3	5.62e-04	21	58	2	28794157
Pubmed	Identification of the Mitochondrial Heme Metabolism Complex.	ABCB10 ALAD	5.62e-04	21	58	2	26287972
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DLGAP4 KIF1B OBSL1 CSMD3 SLC12A5	5.90e-04	407	58	5	12693553
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	EOMES CSMD3	6.18e-04	22	58	2	35245678
Pubmed	Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.	HHIP GLI3	6.18e-04	22	58	2	28432216
Pubmed	Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.	EOMES GLI3	6.76e-04	23	58	2	18728187
Pubmed	Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.	EOMES UNCX	7.37e-04	24	58	2	18171685
Pubmed	Ets2-dependent trophoblast signalling is required for gastrulation progression after primitive streak initiation.	EOMES CHRD	7.37e-04	24	58	2	23552073
Pubmed	Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization.	HHIP GLI3	7.37e-04	24	58	2	12403705
Pubmed	Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.	GLI3 CHRD	7.37e-04	24	58	2	36916392
Pubmed	Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo.	EOMES CHRD	7.37e-04	24	58	2	20573697
Pubmed	Brain development is impaired in c-fos -/- mice.	EOMES GOLGA2	8.00e-04	25	58	2	26143639
Pubmed	A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis.	EOMES GOLGA2	8.00e-04	25	58	2	29587143
Pubmed	A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development.	EOMES GLI3	8.00e-04	25	58	2	32840212
Pubmed	Ofd1 controls dorso-ventral patterning and axoneme elongation during embryonic brain development.	EOMES GLI3	8.66e-04	26	58	2	23300826
Pubmed	Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis.	EOMES GLI3	8.66e-04	26	58	2	26387942
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	HHIP GLI3	8.66e-04	26	58	2	37228654
Pubmed	Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo.	EOMES GOLGA2	8.66e-04	26	58	2	31655624
Pubmed	The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing.	EOMES CHRD	9.34e-04	27	58	2	36197846
Pubmed	Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population.	THBS2 NOD1 NOS3	9.52e-04	115	58	3	20485444
Pubmed	Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing.	EOMES GLI3	1.00e-03	28	58	2	21490064
Pubmed	ARID3A is required for mammalian placenta development.	EOMES AMT	1.00e-03	28	58	2	27965054
Pubmed	A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium.	EOMES GLI3	1.00e-03	28	58	2	20668538
Pubmed	Diverse Functions of Retinoic Acid in Brain Vascular Development.	EOMES RXRB	1.00e-03	28	58	2	27445154
Pubmed	An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.	HHIP GLI3	1.00e-03	28	58	2	35112129
Pubmed	The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap.	EOMES GLI3	1.08e-03	29	58	2	25336744
Pubmed	22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development.	HHIP GLI3	1.08e-03	29	58	2	23077214
Pubmed	Correct patterning of the primitive streak requires the anterior visceral endoderm.	EOMES CHRD	1.15e-03	30	58	2	21445260
Pubmed	ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.	HHIP ADAMTS18	1.15e-03	30	58	2	32882513
Pubmed	Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15.	HHIP GLI3	1.15e-03	30	58	2	28560839
Pubmed	Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2.	UNCX GOLGA2	1.15e-03	30	58	2	26496195
Pubmed	Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.	EOMES DMRTB1	1.15e-03	30	58	2	25804738
Pubmed	Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.	EOMES GLI3	1.40e-03	33	58	2	30914320
Pubmed	PAR3 restricts the expansion of neural precursor cells by regulating hedgehog signaling.	EOMES GLI3	1.40e-03	33	58	2	36218069
Pubmed	The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.	EOMES SLC22A3	1.48e-03	34	58	2	20007774
Pubmed	Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo.	UNCX GLI3	1.48e-03	34	58	2	12086465
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	THBS2 COL5A3 LTBP4	1.51e-03	135	58	3	28675934
Pubmed	Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.	CHRD LTBP4	1.66e-03	36	58	2	23213481
Cytoband	Ensembl 112 genes in cytogenetic band chr3q27	EEF1AKMT4-ECE2 EEF1AKMT4 CHRD	6.14e-04	128	59	3	chr3q27
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	LRP3 POLR1G LTBP4 LENG9 CTU1 ASPDH ADM5	8.22e-04	1192	59	7	chr19q13
Cytoband	9q34.11	IER5L GOLGA2	2.15e-03	53	59	2	9q34.11
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP SSC4D COL5A3 NAA30 SLC12A5	2.51e-06	163	59	5	7a04192710f55acf5a4681d5f09942358fdb02ff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D175\|Adult / Lineage, Cell type, age group and donor	HMCN1 SLC22A3 TMC5 POLR1G	4.45e-05	148	59	4	012845b10850bbc67814da247ee5a69f6d631eaa
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	HMCN1 SLC22A3 TMC5 CSMD3	4.68e-05	150	59	4	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FOXK2 ADAMTS18 COL5A3 FAM83H	5.59e-05	157	59	4	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	11.5-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	ABCB10 COL5A3 ALAD SERF1A	6.47e-05	163	59	4	e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCell	11.5-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	ABCB10 COL5A3 ALAD SERF1A	6.47e-05	163	59	4	31b60e065bac4ad380247964e7574f210106ebae
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EOMES EEF1AKMT4-ECE2 THBS2 COL5A3	6.47e-05	163	59	4	8e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EOMES EEF1AKMT4-ECE2 THBS2 COL5A3	6.47e-05	163	59	4	bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell	LPS_only-Epithelial_airway-Club_cells-Airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 SLC22A3 TMC5 RNF39	6.63e-05	164	59	4	b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCell	LPS_only-Epithelial_airway-Club_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 SLC22A3 TMC5 RNF39	6.63e-05	164	59	4	c5b2001280a43da855017361a3f6071a0e492848
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 SLC22A3 CHRD TMC5	6.94e-05	166	59	4	1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 SLC22A3 CHRD TMC5	6.94e-05	166	59	4	9628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FREM2 HHIP SLC22A3 TMC5	6.94e-05	166	59	4	89e2b8453180983533faccb4275867861876d7ee
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 SLC22A3 TMC5 RNF39	7.44e-05	169	59	4	86041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 SLC22A3 TMC5 RNF39	7.44e-05	169	59	4	8c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	FREM2 SLC22A3 OBSL1 TNKS1BP1	8.33e-05	174	59	4	110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	HHIP THBS2 HMCN1 CHRD	9.10e-05	178	59	4	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THBS2 HMCN1 CHRD LTBP4	9.70e-05	181	59	4	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HHIP THBS2 LINC02898 LTBP4	9.70e-05	181	59	4	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HHIP THBS2 LINC02898 LTBP4	9.70e-05	181	59	4	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7\|TCGA-Prostate / Sample_Type by Project: Shred V9	FARSB GOLGA2 EPHA10 FAM83H	9.91e-05	182	59	4	af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	FREM2 HHIP SLC22A3 TMC5	1.01e-04	183	59	4	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 HMCN1 CSMD3 EPHA10	1.03e-04	184	59	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 HMCN1 CSMD3 EPHA10	1.03e-04	184	59	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 HMCN1 CSMD3 EPHA10	1.03e-04	184	59	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	FREM2 HHIP SLC22A3 TMC5	1.03e-04	184	59	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GLI3 FRMD7 OBSL1 CHRD	1.06e-04	185	59	4	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRMD7 DLGAP4 CHRD LTBP4	1.06e-04	185	59	4	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP HMCN1 COL5A3 LTBP4	1.06e-04	185	59	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP HMCN1 COL5A3 LTBP4	1.06e-04	185	59	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS2 HMCN1 COL5A3 LTBP4	1.08e-04	186	59	4	c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP HMCN1 COL5A3 LTBP4	1.08e-04	186	59	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IER5L TNKS1BP1 FBXL19 LTBP4	1.08e-04	186	59	4	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	FREM2 HHIP SLC22A3 TMC5	1.12e-04	188	59	4	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	HHIP SLC22A3 TMC5 FAM83H	1.15e-04	189	59	4	6f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LTBP4 NOS3 SLC12A5	1.15e-04	189	59	4	2ce330d8078833c05775c481e73770f9ee4a5c88
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 LTBP4 NOS3 SLC12A5	1.15e-04	189	59	4	473c87036e04a058b4a5138438b7ba7e1e766799
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	HHIP SLC22A3 TMC5 FAM83H	1.15e-04	189	59	4	926b5fa3064b501a57ba78583e8af33532add455
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS2 HMCN1 COL5A3 LTBP4	1.17e-04	190	59	4	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS2 HMCN1 COL5A3 LTBP4	1.19e-04	191	59	4	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS2 HMCN1 COL5A3 LTBP4	1.19e-04	191	59	4	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMCN1 ADAMTS18 LTBP4 NOS3	1.19e-04	191	59	4	fcdf3a747038e346a467eae8b7c293592658b53f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THBS2 HMCN1 COL5A3 LTBP4	1.19e-04	191	59	4	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	THBS2 GLI3 COL5A3 LTBP4	1.19e-04	191	59	4	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	THBS2 HMCN1 GLI3 LTBP4	1.19e-04	191	59	4	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMCN1 CHRD ADAMTS18 TNKS1BP1	1.19e-04	191	59	4	dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBS2 HMCN1 COL5A3 LTBP4	1.19e-04	191	59	4	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	THBS2 HMCN1 GLI3 LTBP4	1.19e-04	191	59	4	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	FREM2 HHIP SLC22A3 TMC5	1.19e-04	191	59	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	FREM2 HHIP SLC22A3 TMC5	1.22e-04	192	59	4	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	THBS2 GLI3 CHRD COL5A3	1.22e-04	192	59	4	4ed5040594ba2d0639f0990697504ecef872ca70
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	THBS2 GLI3 CHRD COL5A3	1.22e-04	192	59	4	d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	THBS2 GLI3 COL5A3 LTBP4	1.22e-04	192	59	4	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FREM2 HHIP SLC22A3 TMC5	1.24e-04	193	59	4	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FREM2 HHIP SLC22A3 TMC5	1.24e-04	193	59	4	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP CHRD COL5A3 LTBP4	1.24e-04	193	59	4	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	THBS2 GLI3 CHRD COL5A3	1.24e-04	193	59	4	3d85c28f6ebdcb15e875ad01d52d6c138fbf8525
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FREM2 HHIP SLC22A3 TMC5	1.27e-04	194	59	4	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THBS2 GLI3 CHRD COL5A3	1.29e-04	195	59	4	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	Control_saline-Epithelial_alveolar-AT_2\|Control_saline / Treatment groups by lineage, cell group, cell type	HHIP IER5L SLC22A3 OBSL1	1.34e-04	197	59	4	b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCell	Bronchial_Brush-Epithelial-Basal_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	HMCN1 SNX31 RNF39 LTBP4	1.34e-04	197	59	4	f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCell	Bronchial_Brush-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	HMCN1 SNX31 RNF39 LTBP4	1.37e-04	198	59	4	10a17d7c116dcd6cf847fe6f5d7196d887cad1f9
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HHIP IER5L SLC22A3 OBSL1	1.37e-04	198	59	4	c4e7512f0e1d115f2be8acae6048eda8b6b640b2
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	THBS2 GLI3 OBSL1 TNKS1BP1	1.37e-04	198	59	4	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HHIP IER5L SLC22A3 OBSL1	1.37e-04	198	59	4	d499dced27b0c0e21acfda2c20fa5c114f605085
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HHIP IER5L SLC22A3 OBSL1	1.37e-04	198	59	4	aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	HHIP THBS2 HMCN1 LTBP4	1.37e-04	198	59	4	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FREM2 HHIP SLC22A3 TMC5	1.37e-04	198	59	4	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	background-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HHIP THBS2 HMCN1 LTBP4	1.37e-04	198	59	4	79f32f965aed6a10c5cb803173e3db7b32e07a91
ToppCell	distal-1-mesenchymal-Mesothelial\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	THBS2 GLI3 OBSL1 COL5A3	1.40e-04	199	59	4	8dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FREM2 HHIP SLC22A3 TMC5	1.40e-04	199	59	4	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FREM2 HHIP SLC22A3 TMC5	1.40e-04	199	59	4	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	FREM2 HHIP SLC22A3 TMC5	1.40e-04	199	59	4	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FREM2 HHIP SLC22A3 TMC5	1.40e-04	199	59	4	a38a981cffa61c8444a980916de7414e689a1b63
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	THBS2 HMCN1 GLI3 LTBP4	1.40e-04	199	59	4	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Myofibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	THBS2 HMCN1 COL5A3 LTBP4	1.40e-04	199	59	4	7a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell	mLN-(6)_Macrophage-(60)_Macrophage\|mLN / shred on region, Cell_type, and subtype	SSC4D OBSL1 LRP3 SLC12A5	1.40e-04	199	59	4	1ea28b832c6173b1b58da432aaf21e6cd291561e
ToppCell	mLN-Macrophage-Macrophage\|mLN / Region, Cell class and subclass	SSC4D OBSL1 LRP3 SLC12A5	1.40e-04	199	59	4	6bbec8450afb30347b07da28401a698fc51a3c53
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	THBS2 GLI3 COL5A3 LTBP4	1.42e-04	200	59	4	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HHIP IER5L SLC22A3 OBSL1	1.42e-04	200	59	4	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FREM2 HHIP SLC22A3 TMC5	1.42e-04	200	59	4	b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FREM2 HHIP SLC22A3 TMC5	1.42e-04	200	59	4	35c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FREM2 HHIP SLC22A3 TMC5	1.42e-04	200	59	4	3c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FREM2 HHIP SLC22A3 TMC5	1.42e-04	200	59	4	c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 HMCN1 COL5A3 LTBP4	1.42e-04	200	59	4	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THBS2 HMCN1 COL5A3 LTBP4	1.42e-04	200	59	4	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THBS2 HMCN1 COL5A3 LTBP4	1.42e-04	200	59	4	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	THBS2 GLI3 COL5A3 LTBP4	1.42e-04	200	59	4	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-CR\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EOMES NOD1 DMRTB1	1.83e-04	83	59	3	1ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EOMES NOD1 DMRTB1	1.83e-04	83	59	3	75b27d91a4473286f4b40027e96ac5246f5abe5b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Slc17a8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FREM2 FRMD7 SNX31	2.64e-04	94	59	3	0dc7e645149fa4255cbe1d288524a1ca7ab66376
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 HMCN1 LRP3	4.53e-04	113	59	3	ec4b89e727e1b921b9cb17443774955b95814dd4
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Slc17a8\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FREM2 FRMD7 SNX31	5.26e-04	119	59	3	6435891e6e33e7ae07e0c3a64a66edfbeedb54be
ToppCell	COVID-19_Mild-Neu_3\|World / 5 Neutrophil clusters in COVID-19 patients	HMCN1 GLI3 CSMD3	5.66e-04	122	59	3	2aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HHIP PRRT3 ASPDH	5.80e-04	123	59	3	e0eb95f1da12687230b47f0a7367b6138bc7ff1a
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HHIP PRRT3 ASPDH	5.80e-04	123	59	3	356e2b1b47fdfc2bb2fcd45e44b452fe811f0fd8
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HHIP PRRT3 ASPDH	5.80e-04	123	59	3	15f951b4eb2f39888e51e1af18c329953d253f7f
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HHIP PRRT3 ASPDH	5.80e-04	123	59	3	b06a38d1081b4485b519853d8c9a2cddfb1e9e75
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HHIP THBS2 SSC4D	5.80e-04	123	59	3	87401764a073c1808f214642a9c84299c78f7ec7
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HHIP PRRT3 ASPDH	5.80e-04	123	59	3	f60c1dd89da0e204f73772fe0c319eeca82e7e8a
Disease	Diabetic Angiopathies	THBS2 NOS3	3.74e-04	16	53	2	C0011875
Disease	sickle cell anemia (is_implicated_in)	ALAD NOS3	3.74e-04	16	53	2	DOID:10923 (is_implicated_in)
Disease	Microangiopathy, Diabetic	THBS2 NOS3	3.74e-04	16	53	2	C0025945
Disease	lean body mass	HHIP FOXK2 GLI3 SLC22A3 NOS3	5.89e-04	379	53	5	EFO_0004995
Disease	brain age measurement	EEF1AKMT4-ECE2 EEF1AKMT4	5.89e-04	20	53	2	EFO_0010602
Disease	primary biliary cholangitis (biomarker_via_orthology)	HHIP NOS3	1.16e-03	28	53	2	DOID:12236 (biomarker_via_orthology)
Disease	Colorectal Carcinoma	HHIP ABCB10 GLI3 ADAMTS18 CSMD3 SLC12A5	1.58e-03	702	53	6	C0009402
Disease	liver cirrhosis (biomarker_via_orthology)	ALAD NOS3	1.71e-03	34	53	2	DOID:5082 (biomarker_via_orthology)
Disease	Anorectal Malformations	HHIP GLI3	2.48e-03	41	53	2	C3495676
Disease	epilepsy (implicated_via_orthology)	ALDH5A1 NOS3 SLC12A5	3.17e-03	163	53	3	DOID:1826 (implicated_via_orthology)
Disease	caudate nucleus measurement, functional brain measurement, response to reward	COL5A3 CSMD3	3.25e-03	47	53	2	EFO_0007849, EFO_0008387, EFO_0008396
Disease	Gastrointestinal Stromal Sarcoma	HHIP GLI3	3.25e-03	47	53	2	C3179349

Protein segments in the cluster

Peptide	Gene	Start	Entry
FPAAVCPPGRAQFGP	EOMES	196	O95936
FRCPEPIFQPGLLGQ	ACTL10	121	Q5JWF8
PNTGRPFQCIPGYRA	ADAT2	146	Q7Z6V5
FPGFRPAARGLAQCP	ADM5	91	C9JUS6
LQSCPDPRPFRNGFV	CSMD3	2221	Q7Z407
RCGAFAGPGAPRLPR	ABCB10	101	Q9NRK6
PAEPAQPGACRRDGY	DLGAP4	791	Q9Y2H0
LLACAFPAAGSGPPR	ADAMTS18	6	Q8TE60
ARLAAAGPPGPFRCP	FBXL19	671	Q6PCT2
LRPGDPGFCARARVP	IWS1	741	Q96ST2
GDQGSPPCFLRFPRP	OBSL1	6	O75147
PRPAVPQTRAFGFCN	GLI3	1181	P10071
GAPPLQLPRVCTFRF	FOXK2	131	Q01167
PAFGDRRCYQLPPGA	ALAD	216	P13716
CRVQLGPYQPGRPAA	FRMD8	176	Q9BZ67
GPYQPGRPAACDLRE	FRMD8	181	Q9BZ67
GQELNSPPQPCRRFF	KIF1B	1206	O60333
YEGPVRGLCPFAPRN	ASPDH	176	A6ND91
RLSPKRFPCDFGPGE	FREM2	121	Q5SZK8
FPFGSEFRPLGPCPA	FRMD7	601	Q6ZUT3
APPPACRFFLEGRCR	LENG9	41	Q96B70
FGARCRQPHPGAPAP	LENG9	56	Q96B70
PFLPFQCLQGSGPAR	NOD1	561	Q9Y239
LGPAAPPRQEAFRLC	LRP3	106	O75074
PCGPRVAFLPRQAGL	EPHA10	391	Q5JZY3
RPGLGSNPCIPFFYR	GOLGA2	976	Q08379
RARLCNNPPPAFGGS	HMCN1	4666	Q96RW7
GDPVPCFIRGAPSFR	NOS3	986	P29474
AGRAPPELPERNCGY	EEF1AKMT4-ECE2	6	P0DPD8
FNPDRFGPGAPKPRF	CYP46A1	411	Q9Y6A2
PEGRAAACFFEQPPR	DMRTB1	111	Q96MA1
AACFFEQPPRGRNPG	DMRTB1	116	Q96MA1
PGEGGALPRCRPLQF	CTU1	201	Q7Z7A3
FPAQRGSACRLPAAP	REXO1L1P	176	Q8IX06
ALHCPFDFPQAPLRG	LINC02898	46	Q6ZV80
LRRCRGGFLEPVFPP	DHRSX	26	Q8N5I4
RNQGPREIPGTAFPC	CYP4F30P	11	Q9H0H9
YRAPSGRPGPCADVN	LTBP4	866	Q8N2S1
LGFRLQAFPPALCRP	AMT	11	P48728
QRFPCQAAARPGPDP	FAM83H	546	Q6ZRV2
PAPQYTGPFCGRARV	SASH3	166	O75995
AFPNRSAPLVPCRGG	SLC22A3	116	O75751
FQRCGLRGLASPPPG	PRRT3	831	Q5FWE3
PGFCPQRTPEGDRAF	COL5A3	51	P25940
PGGAPFAPCKRARFE	IER5L	326	Q5T953
AFDPPNFPICLLGNR	SLC12A5	301	Q9H2X9
GPAPGPAQLRCYAGR	ALDH5A1	36	P51649
RENPCFPLPAAGGSR	SERF1A	61	O75920
IPPGLRPRFCAFGGN	POLR1G	141	O15446
RPRFCAFGGNPPVTG	POLR1G	146	O15446
AGRAPPELPERNCGY	EEF1AKMT4	6	P0DPD7
GGLCFPDFPRKQVRG	HHIP	176	Q96QV1
PAFFPGRCAEIFARG	FARSB	541	Q9NSD9
EQLRRVFGNCLPPFP	SNX31	46	Q8N9S9
RPPFLPQRHAAGQCG	RXRB	6	P28702
PGRPRDPNTCFFEGQ	CHRD	696	Q9H2X0
CGLALPVPRPLAFGQ	SSC4D	101	Q8WTU2
CAAPGGVRKAPAPFR	TNKS1BP1	136	Q9C0C2
PSADCGPFRGLPLFI	TMC5	861	Q6UXY8
GFHCLPCPPRYRGNQ	THBS2	616	P35442
QAPGPLGERIFPLFC	RNF39	391	Q9H2S5
AAGLDFAPGLPCAPR	UNCX	356	A6NJT0
AAVEPRCPFPAGAAL	NAA30	21	Q147X3