Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metalloendopeptidase activity	MEP1B ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL2	3.29e-19	120	75	15	GO:0004222
GeneOntologyMolecularFunction	metallopeptidase activity	MEP1B ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL2	8.12e-16	200	75	15	GO:0008237
GeneOntologyMolecularFunction	endopeptidase activity	MEP1B ADAMTS12 ADAMTS10 TMPRSS13 PAMR1 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 CAPN7 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL2 CAPN10	1.36e-15	430	75	19	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	MEP1B ADAMTS12 ADAMTS10 TMPRSS13 PAMR1 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 CAPN7 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL2 CAPN10	2.46e-12	654	75	19	GO:0008233
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBN2 PRG3 HMCN1 SPON1 PAPLN LTBP1 AGRN	6.78e-06	188	75	7	GO:0005201
GeneOntologyMolecularFunction	phosphoglycerate kinase activity	PGK1 PGK2	1.39e-05	2	75	2	GO:0004618
GeneOntologyMolecularFunction	calcium ion binding	FBN2 CELSR3 HMCN1 MEGF6 MEGF8 PAMR1 GNPTAB LTBP1 LTBP3 AGRN NOTCH3 STAB1	2.12e-05	749	75	12	GO:0005509
GeneOntologyMolecularFunction	phosphotransferase activity, carboxyl group as acceptor	PGK1 PGK2	4.17e-05	3	75	2	GO:0016774
GeneOntologyMolecularFunction	transforming growth factor beta binding	LTBP1 LTBP3 AGRN	1.24e-04	26	75	3	GO:0050431
GeneOntologyMolecularFunction	extracellular matrix binding	LTBP1 ADAMTS5 AGRN ADAMTSL2	1.64e-04	73	75	4	GO:0050840
GeneOntologyMolecularFunction	microfibril binding	LTBP1 ADAMTSL2	2.07e-04	6	75	2	GO:0050436
GeneOntologyMolecularFunction	calcium-dependent cysteine-type endopeptidase activity	CAPN7 CAPN10	1.83e-03	17	75	2	GO:0004198
GeneOntologyBiologicalProcess	extracellular matrix organization	ADAMTS12 ADAMTS10 HMCN1 TIE1 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 WNT3A ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	6.80e-17	377	75	19	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	ADAMTS12 ADAMTS10 HMCN1 TIE1 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 WNT3A ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	7.15e-17	378	75	19	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	ADAMTS12 ADAMTS10 HMCN1 TIE1 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 WNT3A ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	7.50e-17	379	75	19	GO:0045229
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN2 LTBP1	7.79e-05	4	75	2	GO:0035583
GeneOntologyBiologicalProcess	axon guidance	CELSR3 MEGF8 SEMA5B WNT3A LMO4 AGRN NOTCH3	7.95e-05	285	75	7	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	CELSR3 MEGF8 SEMA5B WNT3A LMO4 AGRN NOTCH3	8.12e-05	286	75	7	GO:0097485
GeneOntologyBiologicalProcess	artery development	MEGF8 ADAMTS6 ADAMTS9 LTBP1 NOTCH3	1.24e-04	133	75	5	GO:0060840
GeneOntologyBiologicalProcess	negative regulation of chondrocyte differentiation	ADAMTS12 ADAMTS7 LTBP3	1.27e-04	27	75	3	GO:0032331
GeneOntologyBiologicalProcess	positive regulation of melanocyte differentiation	ADAMTS9 ADAMTS20	1.30e-04	5	75	2	GO:0045636
GeneOntologyBiologicalProcess	collagen fibril organization	ADAMTS12 ADAMTS3 ADAMTS7 ADAMTS14	1.70e-04	76	75	4	GO:0030199
GeneOntologyBiologicalProcess	aorta development	MEGF8 ADAMTS6 ADAMTS9 LTBP1	2.07e-04	80	75	4	GO:0035904
GeneOntologyBiologicalProcess	axonogenesis	CELSR3 MEGF8 SEMA5B WNT3A ADGRB1 POTEJ LMO4 AGRN NOTCH3	2.08e-04	566	75	9	GO:0007409
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	ADAMTS12 FBN2 MEGF8 ADAMTS3 ADAMTS7 WNT3A PDGFD LTBP1 LTBP3 ECSIT ADAMTSL2	2.40e-04	850	75	11	GO:0071363
GeneOntologyBiologicalProcess	positive regulation of pigment cell differentiation	ADAMTS9 ADAMTS20	2.71e-04	7	75	2	GO:0050942
GeneOntologyBiologicalProcess	regulation of melanocyte differentiation	ADAMTS9 ADAMTS20	2.71e-04	7	75	2	GO:0045634
GeneOntologyBiologicalProcess	negative regulation of cartilage development	ADAMTS12 ADAMTS7 LTBP3	3.02e-04	36	75	3	GO:0061037
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	ADAMTS12 FBN2 MEGF8 TIE1 ADAMTS3 EFS WNT3A PDGFD LTBP1 LTBP3 ECSIT AGRN ADAMTSL2	3.18e-04	1186	75	13	GO:0007167
GeneOntologyBiologicalProcess	response to growth factor	ADAMTS12 FBN2 MEGF8 ADAMTS3 ADAMTS7 WNT3A PDGFD LTBP1 LTBP3 ECSIT ADAMTSL2	3.32e-04	883	75	11	GO:0070848
GeneOntologyBiologicalProcess	maintenance of protein location in extracellular region	FBN2 LTBP1	3.60e-04	8	75	2	GO:0071694
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	NSMF CELSR3 MEGF8 SEMA5B WNT3A ADGRB1 POTEJ LMO4 AGRN NOTCH3	3.65e-04	748	75	10	GO:0048667
GeneOntologyBiologicalProcess	pigment cell differentiation	ADAMTS9 ADAMTS20 ADAMTSL4	4.14e-04	40	75	3	GO:0050931
GeneOntologyBiologicalProcess	negative regulation of angiogenesis	TIE1 ADAMTS9 ADGRB1 PGK1 STAB1	4.44e-04	175	75	5	GO:0016525
GeneOntologyBiologicalProcess	positive regulation of developmental pigmentation	ADAMTS9 ADAMTS20	4.62e-04	9	75	2	GO:0048087
GeneOntologyBiologicalProcess	regulation of pigment cell differentiation	ADAMTS9 ADAMTS20	4.62e-04	9	75	2	GO:0050932
GeneOntologyBiologicalProcess	negative regulation of blood vessel morphogenesis	TIE1 ADAMTS9 ADGRB1 PGK1 STAB1	4.79e-04	178	75	5	GO:2000181
GeneOntologyBiologicalProcess	negative regulation of vasculature development	TIE1 ADAMTS9 ADGRB1 PGK1 STAB1	5.04e-04	180	75	5	GO:1901343
GeneOntologyBiologicalProcess	axon development	CELSR3 MEGF8 SEMA5B WNT3A ADGRB1 POTEJ LMO4 AGRN NOTCH3	5.22e-04	642	75	9	GO:0061564
GeneOntologyBiologicalProcess	secretion of lysosomal enzymes	GNPTAB NAGPA	5.76e-04	10	75	2	GO:0033299
GeneOntologyBiologicalProcess	neuron projection morphogenesis	NSMF CELSR3 MEGF8 SEMA5B WNT3A ADGRB1 POTEJ LMO4 AGRN NOTCH3	6.29e-04	802	75	10	GO:0048812
GeneOntologyBiologicalProcess	sequestering of extracellular ligand from receptor	FBN2 LTBP1	7.02e-04	11	75	2	GO:0035581
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	NSMF CELSR3 MEGF8 SEMA5B WNT3A ADGRB1 POTEJ LMO4 AGRN NOTCH3	7.39e-04	819	75	10	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	NSMF CELSR3 MEGF8 SEMA5B WNT3A ADGRB1 POTEJ LMO4 AGRN NOTCH3	7.89e-04	826	75	10	GO:0048858
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	CACNA1S FBN2 TIE1 ADAMTS9 WNT3A WNT10B ADGRB1 ADAMTS5 LMO4 ECSIT PGK1 VPS13B NOTCH3 STAB1	8.19e-04	1483	75	14	GO:0048646
GeneOntologyBiologicalProcess	negative regulation of multicellular organismal process	ADAMTS12 RETN GPATCH3 TIE1 ADAMTS7 ADAMTS9 WNT3A WNT10B ADGRB1 ADAMTS18 LTBP3 ADAMTS5 PGK1 STAB1	8.46e-04	1488	75	14	GO:0051241
GeneOntologyBiologicalProcess	regulation of locomotion	FBN2 RETN NSMF MEGF8 TIE1 SEMA5B ADAMTS9 CAPN7 WNT3A PDGFD ADGRB1 LMO4 AGRN	9.18e-04	1327	75	13	GO:0040012
GeneOntologyBiologicalProcess	extracellular regulation of signal transduction	FBN2 LTBP1	9.92e-04	13	75	2	GO:1900115
GeneOntologyBiologicalProcess	extracellular negative regulation of signal transduction	FBN2 LTBP1	9.92e-04	13	75	2	GO:1900116
GeneOntologyBiologicalProcess	pigmentation	ATRN ADAMTS9 ADAMTS20 ADAMTSL4	1.12e-03	125	75	4	GO:0043473
GeneOntologyBiologicalProcess	response to BMP	ADAMTS12 MEGF8 ADAMTS7 WNT3A ECSIT	1.12e-03	215	75	5	GO:0071772
GeneOntologyBiologicalProcess	cellular response to BMP stimulus	ADAMTS12 MEGF8 ADAMTS7 WNT3A ECSIT	1.12e-03	215	75	5	GO:0071773
GeneOntologyBiologicalProcess	bone trabecula formation	FBN2 WNT10B	1.15e-03	14	75	2	GO:0060346
GeneOntologyBiologicalProcess	spinal cord association neuron differentiation	WNT3A LMO4	1.15e-03	14	75	2	GO:0021527
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	FBN2 MEGF8 WNT3A LTBP1 LTBP3 ECSIT ADAMTSL2	1.17e-03	445	75	7	GO:0141091
GeneOntologyBiologicalProcess	myoblast fusion	CACNA1S ADGRB1 ADAMTS5	1.23e-03	58	75	3	GO:0007520
GeneOntologyBiologicalProcess	developmental pigmentation	ADAMTS9 ADAMTS20 ADAMTSL4	1.23e-03	58	75	3	GO:0048066
GeneOntologyBiologicalProcess	regulation of chondrocyte differentiation	ADAMTS12 ADAMTS7 LTBP3	1.30e-03	59	75	3	GO:0032330
GeneOntologyBiologicalProcess	engulfment of apoptotic cell	ADGRB1 XKR5	1.33e-03	15	75	2	GO:0043652
GeneOntologyBiologicalProcess	regulation of developmental pigmentation	ADAMTS9 ADAMTS20	1.33e-03	15	75	2	GO:0048070
GeneOntologyCellularComponent	extracellular matrix	ADAMTS12 ADAMTS10 FBN2 PRG3 HMCN1 MEGF6 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN MUC5B LTBP1 LTBP3 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 AGRN ADAMTSL4 ADAMTSL2	1.20e-20	656	75	26	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS12 ADAMTS10 FBN2 PRG3 HMCN1 MEGF6 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN MUC5B LTBP1 LTBP3 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 AGRN ADAMTSL4 ADAMTSL2	1.30e-20	658	75	26	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTS10 FBN2 PRG3 HMCN1 MEGF6 ADAMTS3 ADAMTS9 SPON1 ADAMTS17 ADAMTS20 PAPLN LTBP1 LTBP3 ADAMTS5 ADAM11 AGRN ADAMTSL4	4.37e-12	530	75	17	GO:0062023
GeneOntologyCellularComponent	microfibril	ADAMTS10 FBN2 LTBP1	1.24e-05	13	75	3	GO:0001527
GeneOntologyCellularComponent	endoplasmic reticulum lumen	ADAMTS7 SPON1 WNT3A PDGFD LTBP1 ADAMTS5 ADAMTSL4	1.88e-04	332	75	7	GO:0005788
GeneOntologyCellularComponent	perikaryon	CNTNAP3B NSMF CNTNAP3 WDFY3 ADAM11	1.24e-03	223	75	5	GO:0043204
HumanPheno	Ovoid vertebral bodies	GNPTAB LTBP1 LTBP3 ADAMTSL2	3.03e-05	34	28	4	HP:0003300
HumanPheno	Lens dislocation	ADAMTS10 FBN2 ADAMTS17 ADAMTSL4	7.78e-05	43	28	4	HP:0000665
HumanPheno	Ectopia lentis	ADAMTS10 FBN2 ADAMTS17 ADAMTSL4	7.78e-05	43	28	4	HP:0001083
HumanPheno	Joint stiffness	ADAMTS10 FBN2 GNPTAB ADAMTS17 LTBP3 ADAMTSL4 ADAMTSL2	8.09e-05	202	28	7	HP:0001387
HumanPheno	Abnormal atrioventricular valve physiology	ADAMTS10 FBN2 MEGF8 GNPTAB ADAMTS17 LTBP3 ADAMTSL2	1.20e-04	215	28	7	HP:0031650
HumanPheno	Abnormal heart valve morphology	ADAMTS10 FBN2 MEGF8 GNPTAB ADAMTS17 MUC5B LTBP1 LTBP3 VPS13B NOTCH3 ADAMTSL2	1.50e-04	588	28	11	HP:0001654
MousePheno	abnormal appendicular skeleton morphology	ADAMTS10 CACNA1S FBN2 MEGF8 ADAMTS6 SPON1 GNPTAB ADAMTS17 LTBP1 LTBP3 LMO4 ADAMTSL3 ADAMTSL2 CAPN10	4.20e-05	896	64	14	MP:0009250
MousePheno	abnormal skeletal muscle mass	ADAMTS10 UBR1 CACNA1S FBN2 AGRN NOTCH3	5.97e-05	149	64	6	MP:0004817
MousePheno	abnormal skin morphology	ADAMTS10 CACNA1S FBN2 PRG3 TMPRSS13 MEGF8 TIE1 ADAMTS3 ADAMTS9 GNPTAB TMEM79 ADAMTS17 ADAMTS20 MUC5B LTBP3 WDFY3 LMO4 VPS13B	6.20e-05	1455	64	18	MP:0002060
Domain	TSP_1	ADAMTS12 ADAMTS10 HMCN1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADGRB1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	5.36e-36	63	75	21	PF00090
Domain	TSP1	ADAMTS12 ADAMTS10 HMCN1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADGRB1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	1.17e-35	65	75	21	SM00209
Domain	TSP1_rpt	ADAMTS12 ADAMTS10 HMCN1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADGRB1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	1.17e-35	65	75	21	IPR000884
Domain	TSP1	ADAMTS12 ADAMTS10 HMCN1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADGRB1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	1.17e-35	65	75	21	PS50092
Domain	ADAM_spacer1	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 ADAMTS14 ADAMTSL4 ADAMTSL2	1.22e-31	23	75	15	IPR010294
Domain	ADAM_spacer1	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 ADAMTS14 ADAMTSL4 ADAMTSL2	1.22e-31	23	75	15	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 ADAMTS14 ADAMTSL3 ADAMTSL2	3.25e-31	24	75	15	IPR013273
Domain	PLAC	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS16 ADAMTS17 ADAMTS18 PAPLN ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	6.27e-28	19	75	13	PS50900
Domain	PLAC	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS16 ADAMTS17 ADAMTS18 PAPLN ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	6.27e-28	19	75	13	IPR010909
Domain	Peptidase_M12B_N	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	1.76e-22	39	75	13	IPR002870
Domain	Pep_M12B_propep	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	1.76e-22	39	75	13	PF01562
Domain	DISINTEGRIN_1	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	2.60e-22	40	75	13	PS00427
Domain	Reprolysin	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	2.60e-22	40	75	13	PF01421
Domain	ADAM_MEPRO	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	2.60e-22	40	75	13	PS50215
Domain	DISINTEGRIN_2	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	2.60e-22	40	75	13	PS50214
Domain	Peptidase_M12B	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	2.60e-22	40	75	13	IPR001590
Domain	Disintegrin_dom	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	3.80e-22	41	75	13	IPR001762
Domain	EGF_3	MEP1B ATRN CNTNAP3B FBN2 CELSR3 HMCN1 MEGF6 MEGF8 TIE1 PAMR1 CNTNAP3 TENM1 LTBP1 LTBP3 ADAM11 NAGPA AGRN NOTCH3 STAB1	5.80e-20	235	75	19	PS50026
Domain	EGF	MEP1B ATRN CNTNAP3B FBN2 CELSR3 HMCN1 MEGF6 MEGF8 TIE1 PAMR1 CNTNAP3 TENM1 LTBP1 LTBP3 ADAM11 NAGPA AGRN NOTCH3 STAB1	5.80e-20	235	75	19	SM00181
Domain	MetalloPept_cat_dom	MEP1B ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	1.16e-19	81	75	14	IPR024079
Domain	-	MEP1B ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	1.16e-19	81	75	14	3.40.390.10
Domain	EGF-like_dom	MEP1B ATRN CNTNAP3B FBN2 CELSR3 HMCN1 MEGF6 MEGF8 TIE1 PAMR1 CNTNAP3 TENM1 LTBP1 LTBP3 ADAM11 NAGPA AGRN NOTCH3 STAB1	1.75e-19	249	75	19	IPR000742
Domain	EGF_1	MEP1B ATRN CNTNAP3B FBN2 CELSR3 HMCN1 MEGF6 MEGF8 TIE1 PAMR1 CNTNAP3 TENM1 LTBP1 LTBP3 ADAM11 NAGPA AGRN NOTCH3 STAB1	2.74e-19	255	75	19	PS00022
Domain	PLAC	ADAMTS10 ADAMTS6 ADAMTS16 ADAMTS17 ADAMTS18 PAPLN ADAMTSL3 ADAMTSL4 ADAMTSL2	3.25e-19	14	75	9	PF08686
Domain	EGF_2	MEP1B ATRN CNTNAP3B FBN2 CELSR3 HMCN1 MEGF6 MEGF8 TIE1 PAMR1 CNTNAP3 TENM1 LTBP1 LTBP3 ADAM11 NAGPA AGRN NOTCH3 STAB1	5.69e-19	265	75	19	PS01186
Domain	ZINC_PROTEASE	MEP1B ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14	1.97e-18	98	75	14	PS00142
Domain	EGF-like_CS	MEP1B ATRN FBN2 CELSR3 HMCN1 MEGF6 MEGF8 TIE1 PAMR1 CNTNAP3 TENM1 LTBP1 LTBP3 ADAM11 NAGPA AGRN NOTCH3 STAB1	1.08e-17	261	75	18	IPR013032
Domain	EGF	MEP1B ATRN CELSR3 HMCN1 MEGF6 TIE1 PAMR1 CNTNAP3 LTBP1 NAGPA AGRN NOTCH3 STAB1	2.83e-15	126	75	13	PF00008
Domain	EGF_CA	FBN2 CELSR3 HMCN1 MEGF6 MEGF8 PAMR1 LTBP1 LTBP3 AGRN NOTCH3 STAB1	2.01e-12	122	75	11	SM00179
Domain	EGF-like_Ca-bd_dom	FBN2 CELSR3 HMCN1 MEGF6 MEGF8 PAMR1 LTBP1 LTBP3 AGRN NOTCH3 STAB1	2.41e-12	124	75	11	IPR001881
Domain	EGF_extracell	ATRN MEGF6 TIE1 TENM1 ADAM11 NAGPA NOTCH3 STAB1	9.97e-11	60	75	8	IPR013111
Domain	EGF_2	ATRN MEGF6 TIE1 TENM1 ADAM11 NAGPA NOTCH3 STAB1	9.97e-11	60	75	8	PF07974
Domain	CYSTEINE_SWITCH	ADAMTS12 ADAMTS7 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS14	2.55e-10	41	75	7	PS00546
Domain	Pept_M10_metallopeptidase	ADAMTS12 ADAMTS7 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS14	3.63e-10	43	75	7	IPR001818
Domain	Growth_fac_rcpt_	ATRN FBN2 HMCN1 MEGF6 MEGF8 TIE1 LTBP1 LTBP3 NOTCH3 STAB1	6.43e-10	156	75	10	IPR009030
Domain	Laminin_EGF	ATRN CELSR3 MEGF6 MEGF8 AGRN STAB1	5.06e-09	35	75	6	PF00053
Domain	EGF_Lam	ATRN CELSR3 MEGF6 MEGF8 AGRN STAB1	5.06e-09	35	75	6	SM00180
Domain	ASX_HYDROXYL	FBN2 CELSR3 HMCN1 MEGF6 MEGF8 LTBP1 LTBP3 NOTCH3	6.38e-09	100	75	8	PS00010
Domain	Laminin_EGF	ATRN CELSR3 MEGF6 MEGF8 AGRN STAB1	8.53e-09	38	75	6	IPR002049
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN2 CELSR3 HMCN1 MEGF6 MEGF8 LTBP1 LTBP3 NOTCH3	1.01e-08	106	75	8	IPR000152
Domain	EGF_CA	FBN2 HMCN1 MEGF6 MEGF8 LTBP1 LTBP3 NOTCH3	5.28e-08	86	75	7	PF07645
Domain	EGF_LAM_2	ATRN CELSR3 MEGF8 AGRN STAB1	1.20e-07	30	75	5	PS50027
Domain	EGF_LAM_1	ATRN CELSR3 MEGF8 AGRN STAB1	1.20e-07	30	75	5	PS01248
Domain	EGF_Ca-bd_CS	FBN2 HMCN1 MEGF6 MEGF8 LTBP1 LTBP3 NOTCH3	1.22e-07	97	75	7	IPR018097
Domain	EGF_CA	FBN2 HMCN1 MEGF6 MEGF8 LTBP1 LTBP3 NOTCH3	1.40e-07	99	75	7	PS01187
Domain	TB	FBN2 LTBP1 LTBP3	2.15e-06	7	75	3	PF00683
Domain	cEGF	FBN2 HMCN1 LTBP1 LTBP3	3.35e-06	26	75	4	IPR026823
Domain	cEGF	FBN2 HMCN1 LTBP1 LTBP3	3.35e-06	26	75	4	PF12662
Domain	-	FBN2 LTBP1 LTBP3	3.43e-06	8	75	3	3.90.290.10
Domain	ACR	ADAMTS17 ADAMTS5 ADAM11 ADAMTS14	3.92e-06	27	75	4	SM00608
Domain	ADAM_Cys-rich	ADAMTS17 ADAMTS5 ADAM11 ADAMTS14	3.92e-06	27	75	4	IPR006586
Domain	hEGF	FBN2 MEGF6 LTBP3 NOTCH3	4.56e-06	28	75	4	PF12661
Domain	TB	FBN2 LTBP1 LTBP3	5.13e-06	9	75	3	PS51364
Domain	TB_dom	FBN2 LTBP1 LTBP3	5.13e-06	9	75	3	IPR017878
Domain	PGLYCERATE_KINASE	PGK1 PGK2	1.59e-05	2	75	2	PS00111
Domain	Pept_M12B_GON-ADAMTSs	ADAMTS9 ADAMTS20	1.59e-05	2	75	2	IPR012314
Domain	Phosphoglycerate_kinase_N	PGK1 PGK2	1.59e-05	2	75	2	IPR015824
Domain	GON	ADAMTS9 ADAMTS20	1.59e-05	2	75	2	PF08685
Domain	Phosphoglycerate_kinase_CS	PGK1 PGK2	1.59e-05	2	75	2	IPR015911
Domain	Phosphoglycerate_kinase_C	PGK1 PGK2	1.59e-05	2	75	2	IPR015901
Domain	GON	ADAMTS9 ADAMTS20	1.59e-05	2	75	2	PS51046
Domain	-	PGK1 PGK2	1.59e-05	2	75	2	3.40.50.1270
Domain	-	PGK1 PGK2	1.59e-05	2	75	2	3.40.50.1260
Domain	PGK	PGK1 PGK2	1.59e-05	2	75	2	PF00162
Domain	LAM_G_DOMAIN	CNTNAP3B CELSR3 CNTNAP3 AGRN	1.60e-05	38	75	4	PS50025
Domain	LamG	CNTNAP3B CELSR3 CNTNAP3 AGRN	2.88e-05	44	75	4	SM00282
Domain	CUB	ATRN MEGF8 PAMR1 PDGFD	4.43e-05	49	75	4	PF00431
Domain	Phosphoglycerate_kinase	PGK1 PGK2	4.76e-05	3	75	2	IPR001576
Domain	CUB	ATRN MEGF8 PAMR1 PDGFD	4.80e-05	50	75	4	SM00042
Domain	-	ATRN MEGF8 PAMR1 PDGFD	5.61e-05	52	75	4	2.60.120.290
Domain	CUB	ATRN MEGF8 PAMR1 PDGFD	6.05e-05	53	75	4	PS01180
Domain	CUB_dom	ATRN MEGF8 PAMR1 PDGFD	8.06e-05	57	75	4	IPR000859
Domain	Laminin_G	CNTNAP3B CELSR3 CNTNAP3 AGRN	8.63e-05	58	75	4	IPR001791
Domain	LNR	GNPTAB NOTCH3	1.58e-04	5	75	2	PS50258
Domain	ConA-like_dom	MEP1B CNTNAP3B CELSR3 CNTNAP3 WDFY3 AGRN	2.49e-04	219	75	6	IPR013320
Domain	PSI	ATRN MEGF8 SEMA5B	2.84e-04	32	75	3	PF01437
Domain	Plexin_repeat	ATRN MEGF8 SEMA5B	2.84e-04	32	75	3	IPR002165
Domain	Notch_dom	GNPTAB NOTCH3	3.30e-04	7	75	2	IPR000800
Domain	Notch	GNPTAB NOTCH3	3.30e-04	7	75	2	PF00066
Domain	NL	GNPTAB NOTCH3	3.30e-04	7	75	2	SM00004
Domain	ANK	POTEM POTEJ POTEB2 POTEH POTEB NOTCH3	5.15e-04	251	75	6	SM00248
Domain	ANK_REPEAT	POTEM POTEJ POTEB2 POTEH POTEB NOTCH3	5.37e-04	253	75	6	PS50088
Domain	Ankyrin_rpt-contain_dom	POTEM POTEJ POTEB2 POTEH POTEB NOTCH3	5.48e-04	254	75	6	IPR020683
Domain	ANK_REP_REGION	POTEM POTEJ POTEB2 POTEH POTEB NOTCH3	5.48e-04	254	75	6	PS50297
Domain	Laminin_G_2	CNTNAP3B CELSR3 CNTNAP3	5.52e-04	40	75	3	PF02210
Domain	-	CELSR3 CNTNAP3 WDFY3 AGRN	5.79e-04	95	75	4	2.60.120.200
Domain	Ankyrin_rpt	POTEM POTEJ POTEB2 POTEH POTEB NOTCH3	6.45e-04	262	75	6	IPR002110
Domain	PSI	ATRN MEGF8 SEMA5B	7.32e-04	44	75	3	IPR016201
Domain	PSI	ATRN MEGF8 SEMA5B	8.34e-04	46	75	3	SM00423
Domain	-	HMCN1 STAB1	8.55e-04	11	75	2	2.40.155.10
Domain	GFP-like	HMCN1 STAB1	8.55e-04	11	75	2	IPR023413
Domain	GAIN_dom_N	CELSR3 ADGRB1	8.55e-04	11	75	2	IPR032471
Domain	GAIN	CELSR3 ADGRB1	8.55e-04	11	75	2	PF16489
Domain	-	ATRN MEGF8 LCMT2	9.45e-04	48	75	3	2.120.10.80
Domain	EGF_3	MEGF8 STAB1	1.02e-03	12	75	2	PF12947
Domain	Calpain_III	CAPN7 CAPN10	1.02e-03	12	75	2	IPR022683
Domain	EGF_dom	MEGF8 STAB1	1.02e-03	12	75	2	IPR024731
Domain	calpain_III	CAPN7 CAPN10	1.02e-03	12	75	2	SM00720
Domain	C2_III	CAPN7 CAPN10	1.02e-03	12	75	2	IPR033883
Domain	Calpain_domain_III	CAPN7 CAPN10	1.21e-03	13	75	2	IPR022682
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	1.68e-34	39	56	18	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	1.68e-34	39	56	18	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 MUC5B ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 NOTCH3 ADAMTSL2	1.47e-33	68	56	20	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 MUC5B ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 AGRN ADAMTSL4 NOTCH3 ADAMTSL2	2.95e-28	143	56	21	M27275
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 MUC5B ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	4.89e-27	109	56	19	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 MUC5B ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	7.10e-27	111	56	19	M27416
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 MUC5B ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 AGRN ADAMTSL4 NOTCH3 ADAMTSL2	5.59e-23	250	56	21	M27554
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	FBN2 ADAMTS3 ADAMTS9 CAPN7 ADAMTS16 ADAMTS18 LTBP1 LTBP3 ADAMTS5 ADAMTS14 AGRN CAPN10	1.68e-09	300	56	12	M610
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	ADAMTS12 ADAMTS10 MEGF6 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 DCAF17 ADAMTS18 ADAMTS20 MUC5B LTBP1 ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	4.88e-09	1389	56	22	MM15307
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	FBN2 MEGF6 ADAMTS3 CAPN7 LTBP1 LTBP3 ADAMTS5 ADAMTS14 AGRN CAPN10	6.02e-08	258	56	10	MM14572
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	ADAMTS12 ADAMTS10 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADAMTS16 ADAMTS17 DCAF17 ADAMTS18 ADAMTS20 MUC5B LTBP1 ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	8.20e-08	1475	56	21	M19806
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	FBN2 ADAMTS9 CAPN7 ADAMTS16 ADAMTS18 ADAMTS5 CAPN10	1.27e-06	140	56	7	M587
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	ADAMTS10 LTBP1 LTBP3 ADAMTSL2	8.64e-05	59	56	4	M39886
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN2 LTBP1 LTBP3	2.71e-04	32	56	3	MM14854
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN2 LTBP1 LTBP3	4.19e-04	37	56	3	M27134
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	LTBP1 LTBP3	4.27e-04	8	56	2	M47850
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN2 LTBP1 LTBP3	4.90e-04	39	56	3	MM14601
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN2 LTBP1 LTBP3	7.01e-04	44	56	3	M26969
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	FBN2 CAPN7 ADAMTS5 CAPN10	1.08e-03	114	56	4	MM14571
Pathway	WP_CORI_CYCLE	PGK1 PGK2	2.03e-03	17	56	2	M39604
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION	WNT3A WNT10B	2.54e-03	19	56	2	M47836
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS12 ADAMTS10 HMCN1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 ADGRB1 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN ADAMTS5 THSD7B ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	1.24e-39	75	76	21	20637190
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS12 ADAMTS10 ADAMTS7 ADAMTS9 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5	1.75e-19	12	76	8	25770910
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS5	2.14e-17	10	76	7	11167130
Pubmed	Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.	ADAMTS9 ADAMTS16 ADAMTS18 ADAMTS5	2.10e-11	4	76	4	16507336
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	HMCN1 ADAMTS3 ADAMTS9 SPON1 ADAMTS20 ADAM11 AGRN	1.01e-10	64	76	7	22261194
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	ADAMTS3 ADAMTS9 ADAMTS16 ADAMTS18 ADAMTS5	1.87e-10	16	76	5	30579834
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEM POTEB2 POTEH POTEB	3.15e-10	6	76	4	17171436
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS14	7.33e-10	7	76	4	11867212
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEJ POTEB2 POTEH POTEB	1.46e-09	8	76	4	12475935
Pubmed	Hydrocephalus in mouse B3glct mutants is likely caused by defects in multiple B3GLCT substrates in ependymal cells and subcommissural organ.	ADAMTS3 ADAMTS9 SPON1 ADAMTS20	6.87e-09	11	76	4	33909046
Pubmed	A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.	ADAMTS9 ADAMTS20 ADAMTS5	1.00e-08	3	76	3	24753090
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	ADAMTS10 ADAMTS3 LTBP1 ADAMTS14	2.82e-08	15	76	4	38871984
Pubmed	Identification and characterization of TSAP, a novel gene specifically expressed in testis during spermatogenesis.	POTEM POTEH POTEB	4.00e-08	4	76	3	17342726
Pubmed	ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.	ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS5	4.90e-08	17	76	4	10464288
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS10 FBN2 ADAMTS6 ADAMTS17	6.29e-08	18	76	4	35503090
Pubmed	Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure.	ADAMTS12 ADAMTS6 ADAMTS16	1.00e-07	5	76	3	29625437
Pubmed	Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.	ADAMTS10 ADAMTSL4 ADAMTSL2	1.00e-07	5	76	3	29758265
Pubmed	Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.	ADAMTS9 ADAMTS16 ADAMTS5	1.00e-07	5	76	3	22562232
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	MEGF6 MEGF8 EFS LTBP1 LTBP3 AGRN ADAMTSL4 NOTCH3 ADAMTSL2 STAB1	3.98e-07	560	76	10	21653829
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	PRG3 SEMA5B ADAMTS16 PAPLN LTBP3 ADAMTS5 NOTCH3	4.07e-07	210	76	7	16537572
Pubmed	Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.	ADAMTS9 ADAMTS20 ADAMTS5	5.57e-07	8	76	3	21041365
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	CELSR3 MEGF6 MEGF8	8.34e-07	9	76	3	9693030
Pubmed	Tracing the origin of hair follicle stem cells.	FBN2 WNT10B ADAMTS17 ADAMTS20	1.05e-06	35	76	4	34108685
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	PAMR1 ADAMTS7 PDGFD LTBP1 ADAMTS5 AGRN ADAMTSL4	1.24e-06	248	76	7	24006456
Pubmed	Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.	TIE1 ADAMTS9 ADAMTS18 ADAMTS5	1.47e-06	38	76	4	18267097
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	HMCN1 SPON1 ADAMTS17 PAPLN LTBP1 AGRN	1.85e-06	167	76	6	22159717
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ATRN ADAMTSL3 LCMT2 VPS13B ADAMTSL2	3.55e-06	105	76	5	9628581
Pubmed	Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene.	PGK1 PGK2	4.71e-06	2	76	2	9023984
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	4.71e-06	2	76	2	31150793
Pubmed	Lmo4-resistin signaling contributes to adipose tissue-liver crosstalk upon weight cycling.	RETN LMO4	4.71e-06	2	76	2	32030835
Pubmed	Wnt3a increases the metastatic potential of non-small cell lung cancer cells in vitro in part via its upregulation of Notch3.	WNT3A NOTCH3	4.71e-06	2	76	2	25572698
Pubmed	Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.	PGK1 PGK2	4.71e-06	2	76	2	3453121
Pubmed	A factor stimulating transcription of the testis-specific Pgk-2 gene recognizes a sequence similar to the binding site for a transcription inhibitor of the somatic-type Pgk-1 gene.	PGK1 PGK2	4.71e-06	2	76	2	8441629
Pubmed	ADAMTS: novel proteases expressed by activated mast cells.	ADAMTS9 ADAMTS5	4.71e-06	2	76	2	23154421
Pubmed	Transcription switch of two phosphoglycerate kinase genes during spermatogenesis as determined with mouse testis sections in situ.	PGK1 PGK2	4.71e-06	2	76	2	2298243
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	4.71e-06	2	76	2	26807827
Pubmed	Selective activation of testis-specific genes in cultured rat spermatogenic cells.	PGK1 PGK2	4.71e-06	2	76	2	2166582
Pubmed	Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.	ADAMTS9 ADAMTS20	4.71e-06	2	76	2	12514189
Pubmed	Lentiviral shRNA knock-down of ADAMTS-5 and -9 restores matrix deposition in 3D chondrocyte culture.	ADAMTS9 ADAMTS5	4.71e-06	2	76	2	20568084
Pubmed	Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage.	ADAMTS9 ADAMTS5	4.71e-06	2	76	2	29137610
Pubmed	The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.	ADAMTS12 ADAMTS7	4.71e-06	2	76	2	19098927
Pubmed	Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme.	PGK1 PGK2	4.71e-06	2	76	2	5009693
Pubmed	The family of mouse phosphoglycerate kinase genes and pseudogenes.	PGK1 PGK2	4.71e-06	2	76	2	2829366
Pubmed	ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.	ADAMTS10 ADAMTS6	4.71e-06	2	76	2	27779234
Pubmed	Characterization of phosphoglycerate kinase from human spermatozoa.	PGK1 PGK2	4.71e-06	2	76	2	1278465
Pubmed	The role of ADAMTS6 and ADAMTS17 polymorphisms in susceptibility to lumbar disc herniation in Chinese Han population.	ADAMTS6 ADAMTS17	4.71e-06	2	76	2	36810712
Pubmed	Differential appearance of DNase I-hypersensitive sites correlates with differential transcription of Pgk genes during spermatogenesis in the mouse.	PGK1 PGK2	4.71e-06	2	76	2	8662942
Pubmed	Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits.	LTBP1 NOTCH3	4.71e-06	2	76	2	25190493
Pubmed	Evaluation of ADAMTS12, ADAMTS16, ADAMTS18 and IL-33 serum levels in pre-eclampsia.	ADAMTS16 ADAMTS18	4.71e-06	2	76	2	26382559
Pubmed	Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature.	ADAMTS10 ADAMTS17	4.71e-06	2	76	2	19836009
Pubmed	Negative effects of ADAMTS-7 and ADAMTS-12 on endplate cartilage differentiation.	ADAMTS12 ADAMTS7	4.71e-06	2	76	2	22247065
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	MEGF6 MEGF8 LTBP1 LTBP3 AGRN	6.29e-06	118	76	5	21078624
Pubmed	Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.	ADAMTS9 ADAMTS20 ADAMTS5	6.67e-06	17	76	3	22183742
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ATRN FBN2 CELSR3 MEGF8 GNPTAB CNTNAP3 LTBP1 LTBP3 CERS1 NAGPA AGRN NOTCH3	1.10e-05	1201	76	12	35696571
Pubmed	ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.	ADAMTS9 ADAMTS20 ADAMTS5	1.11e-05	20	76	3	19922873
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	STARD8 MEGF6 ADAMTS9 SPON1 GNPTAB ADAMTS16 LCMT2 ADAMTSL2	1.25e-05	493	76	8	15368895
Pubmed	The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.	ADAMTS3 ADAMTS14	1.41e-05	3	76	2	25863161
Pubmed	Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.	ADAMTS3 ADAMTS14	1.41e-05	3	76	2	11741898
Pubmed	Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene.	PGK1 PGK2	1.41e-05	3	76	2	1380672
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	ADAMTS10 FBN2	1.41e-05	3	76	2	30201140
Pubmed	Mutations in the lysosomal enzyme-targeting pathway and persistent stuttering.	GNPTAB NAGPA	1.41e-05	3	76	2	20147709
Pubmed	Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3).	LTBP1 LTBP3	1.41e-05	3	76	2	7730318
Pubmed	Mucolipidosis types II and III and non-syndromic stuttering are associated with different variants in the same genes.	GNPTAB NAGPA	1.41e-05	3	76	2	26130485
Pubmed	Variants in GNPTAB, GNPTG and NAGPA genes are associated with stutterers.	GNPTAB NAGPA	1.41e-05	3	76	2	29289611
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	RETN MUC5B	1.41e-05	3	76	2	29604272
Pubmed	Geleophysic Dysplasia	LTBP3 ADAMTSL2	1.41e-05	3	76	2	20301776
Pubmed	ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation.	LTBP1 ADAMTSL2	1.41e-05	3	76	2	18677313
Pubmed	Wnt-10b, uniquely among Wnts, promotes epithelial differentiation and shaft growth.	WNT3A WNT10B	1.41e-05	3	76	2	18155657
Pubmed	ADAMTSL-3/punctin-2, a novel glycoprotein in extracellular matrix related to the ADAMTS family of metalloproteases.	ADAMTSL3 ADAMTSL2	1.41e-05	3	76	2	14667842
Pubmed	Association study of stuttering candidate genes GNPTAB, GNPTG and NAGPA with dyslexia in Chinese population.	GNPTAB NAGPA	1.41e-05	3	76	2	25643770
Pubmed	A role for inherited metabolic deficits in persistent developmental stuttering.	GNPTAB NAGPA	1.41e-05	3	76	2	22884963
Pubmed	Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate.	ADAMTS9 ADAMTS20	1.41e-05	3	76	2	37169079
Pubmed	ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse.	ADAMTS9 ADAMTS5	1.41e-05	3	76	2	23562508
Pubmed	Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells.	LTBP1 LTBP3	1.41e-05	3	76	2	18672106
Pubmed	Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.	LTBP1 LTBP3	1.41e-05	3	76	2	10743502
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	CNTNAP3B CNTNAP3 LMO4	1.50e-05	22	76	3	26494785
Pubmed	ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.	FBN2 ADAMTS9 ADAMTS20	1.72e-05	23	76	3	26027930
Pubmed	Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.	ADAMTS3 ADAMTS9 ADAMTS5	1.96e-05	24	76	3	29791855
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	FBN2 ADAMTS18 NOTCH3	2.51e-05	26	76	3	34189436
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN2 LTBP1	2.82e-05	4	76	2	12429738
Pubmed	Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling.	WNT3A WNT10B	2.82e-05	4	76	2	18045882
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP1 LTBP3	2.82e-05	4	76	2	15611103
Pubmed	Weill-Marchesani Syndrome	ADAMTS10 ADAMTS17	2.82e-05	4	76	2	20301293
Pubmed	Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin.	ADAMTS12 ADAMTS7	2.82e-05	4	76	2	18485748
Pubmed	ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.	ADAMTS3 ADAMTS16	2.82e-05	4	76	2	28088271
Pubmed	Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15: a novel versican-cleaving proteoglycanase.	ADAMTS9 ADAMTS5	2.82e-05	4	76	2	24220035
Pubmed	Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart.	LTBP1 LTBP3	2.82e-05	4	76	2	9008713
Pubmed	The latent transforming growth factor beta binding protein (LTBP) family.	LTBP1 LTBP3	2.82e-05	4	76	2	11104663
Pubmed	Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.	ADAMTS3 ADAMTS14	2.82e-05	4	76	2	22205175
Pubmed	Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.	LTBP1 LTBP3	2.82e-05	4	76	2	16157329
Pubmed	Genetic factors and therapy outcomes in persistent developmental stuttering.	GNPTAB NAGPA	2.82e-05	4	76	2	31003007
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	POTEM POTEJ POTEB2 POTEH POTEB	3.00e-05	163	76	5	24316575
Pubmed	p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.	WNT3A WNT10B NOTCH3	3.90e-05	30	76	3	16524929
Pubmed	ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.	FBN2 ADAMTS18 LTBP1	3.90e-05	30	76	3	32882513
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	FBN2 HMCN1 MEGF6 LTBP1 AGRN	4.22e-05	175	76	5	28071719
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	ATRN AGRN NOTCH3	4.31e-05	31	76	3	11431694
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	ATRN NOTCH3 STAB1	4.31e-05	31	76	3	31550482
Pubmed	Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.	FBN2 LTBP1 ADAMTSL2	4.31e-05	31	76	3	25762570
Pubmed	Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.	LTBP1 LTBP3	4.69e-05	5	76	2	19897194
Pubmed	[ADAMTS family--new extracellular matrix degrading enzyme].	ADAMTS3 ADAMTS5	4.69e-05	5	76	2	11831030
Interaction	FBXO2 interactions	ATRN CNTNAP3B FBN2 CELSR3 MEGF8 ADAMTS7 GNPTAB WNT10B CNTNAP3 AGRN NOTCH3	3.37e-07	411	75	11	int:FBXO2
Interaction	IGFL3 interactions	ATRN FBN2 ADAMTS7 ADAM11 AGRN NOTCH3	3.56e-07	75	75	6	int:IGFL3
Interaction	CFC1 interactions	UBR1 CNTNAP3B MEGF8 ADAMTS7 CNTNAP3 PAPLN AGRN	4.40e-07	126	75	7	int:CFC1
Interaction	ADAMTS12 interactions	ADAMTS12 ADAMTS10 UBR1 ADAMTS7 ADAMTS6	1.88e-06	55	75	5	int:ADAMTS12
Interaction	CBLN4 interactions	CNTNAP3B MEGF8 ADAMTS7 CNTNAP3 ADAM11 AGRN	7.85e-06	127	75	6	int:CBLN4
Interaction	SLURP1 interactions	ATRN CNTNAP3B MEGF8 ADAMTS7 SPON1 CNTNAP3	1.61e-05	144	75	6	int:SLURP1
Interaction	SDF2L1 interactions	ATRN CNTNAP3B MEGF8 ADAMTS7 WNT3A CNTNAP3 PAPLN AGRN	2.59e-05	322	75	8	int:SDF2L1
Interaction	TRGV3 interactions	CNTNAP3B MEGF8 ADAMTS7 CNTNAP3	5.23e-05	55	75	4	int:TRGV3
Interaction	HOXA1 interactions	MEGF6 MEGF8 LTBP1 LTBP3 AGRN ADAMTSL4 NOTCH3 ADAMTSL2	5.28e-05	356	75	8	int:HOXA1
Interaction	ZFP41 interactions	FBN2 LTBP1 AGRN NOTCH3	6.02e-05	57	75	4	int:ZFP41
Interaction	DNASE1L1 interactions	ATRN MEGF8 ADAMTS7 CNTNAP3 ADAMTS14	8.52e-05	120	75	5	int:DNASE1L1
Interaction	PRG2 interactions	CNTNAP3B FBN2 ADAMTS7 CNTNAP3 LTBP3 ADAMTS14 NOTCH3	9.18e-05	285	75	7	int:PRG2
Interaction	NTN5 interactions	FBN2 LTBP1 NOTCH3	9.47e-05	24	75	3	int:NTN5
Interaction	CACNA1A interactions	MEGF6 MEGF8 LTBP1 LTBP3 AGRN	9.57e-05	123	75	5	int:CACNA1A
Interaction	CRIPTO interactions	ATRN UBR1 MEGF8 ADAMTS7	1.27e-04	69	75	4	int:CRIPTO
Interaction	ADAMTS19 interactions	ADAMTS16 ADAMTS18	1.36e-04	5	75	2	int:ADAMTS19
Interaction	GPIHBP1 interactions	CNTNAP3B ADAMTS7 CNTNAP3 ADAMTS17 ADAM11	1.38e-04	133	75	5	int:GPIHBP1
Interaction	FIBIN interactions	CNTNAP3B MEGF8 ADAMTS7 CNTNAP3	1.42e-04	71	75	4	int:FIBIN
Interaction	NOTCH2 interactions	FBN2 PRG3 ADAMTS9 WNT3A WNT10B ADAMTS17 LTBP1 NOTCH3	1.74e-04	423	75	8	int:NOTCH2
Interaction	CST11 interactions	ATRN CNTNAP3B ADAMTS7 CNTNAP3	1.76e-04	75	75	4	int:CST11
Interaction	MBD1 interactions	MEGF6 TENM1 LTBP3 NOTCH3	1.95e-04	77	75	4	int:MBD1
Interaction	FBXO6 interactions	ATRN CNTNAP3B FBN2 MEGF8 ADAMTS7 MUC5B LTBP1 LTBP3 AGRN ADAMTSL4	3.13e-04	717	75	10	int:FBXO6
Interaction	COL6A2 interactions	ADAMTS12 PRG3 WNT10B AGRN	3.55e-04	90	75	4	int:COL6A2
Interaction	ELSPBP1 interactions	ATRN MEGF8 ADAMTS7 AGRN	3.86e-04	92	75	4	int:ELSPBP1
Interaction	C1orf54 interactions	CELSR3 CNTNAP3 ADAMTS17 LTBP1 AGRN	3.98e-04	167	75	5	int:C1orf54
Interaction	CRISP2 interactions	ATRN ADAMTS7 CNTNAP3	4.43e-04	40	75	3	int:CRISP2
Interaction	ADAMTS6 interactions	ADAMTS12 ADAMTS6	4.84e-04	9	75	2	int:ADAMTS6
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS12 ADAMTS10 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAMTS14	1.09e-26	19	56	12	50
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEM POTEJ POTEB2 POTEH POTEB	3.00e-10	13	56	5	685
GeneFamily	ADAMTS like	PAPLN ADAMTSL3 ADAMTSL4 ADAMTSL2	2.87e-09	7	56	4	947
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP1 LTBP3	5.63e-05	4	56	2	628
GeneFamily	Ankyrin repeat domain containing	POTEM POTEJ POTEB2 POTEH POTEB NOTCH3	1.00e-04	242	56	6	403
GeneFamily	C2 domain containing\|Calpains	CAPN7 CAPN10	9.64e-04	15	56	2	975
GeneFamily	Wnt family\|Endogenous ligands	WNT3A WNT10B	1.56e-03	19	56	2	360
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ATRN PRG3	7.15e-03	41	56	2	1298
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HMCN1 PAPLN ADAMTSL3	1.36e-02	161	56	3	593
Coexpression	NABA_MATRISOME	MEP1B ADAMTS12 ADAMTS10 FBN2 PRG3 HMCN1 MEGF6 MEGF8 PAMR1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 WNT3A PDGFD WNT10B ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN MUC5B LTBP1 LTBP3 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 AGRN ADAMTSL4 ADAMTSL2	8.93e-27	1008	76	33	MM17056
Coexpression	NABA_MATRISOME	MEP1B ADAMTS12 ADAMTS10 FBN2 PRG3 HMCN1 MEGF6 MEGF8 PAMR1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 SPON1 WNT3A PDGFD WNT10B ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 PAPLN MUC5B LTBP1 LTBP3 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 AGRN ADAMTSL4 ADAMTSL2	1.57e-26	1026	76	33	M5889
Coexpression	NABA_ECM_REGULATORS	MEP1B ADAMTS12 ADAMTS10 PAMR1 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	7.22e-21	238	76	18	M3468
Coexpression	NABA_ECM_REGULATORS	MEP1B ADAMTS12 ADAMTS10 PAMR1 ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	9.77e-21	242	76	18	MM17062
Coexpression	NABA_MATRISOME_ASSOCIATED	MEP1B ADAMTS12 ADAMTS10 MEGF6 MEGF8 PAMR1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 WNT3A PDGFD WNT10B ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 MUC5B ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	2.36e-20	738	76	25	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	MEP1B ADAMTS12 ADAMTS10 MEGF6 MEGF8 PAMR1 ADAMTS3 SEMA5B ADAMTS7 ADAMTS6 ADAMTS9 WNT3A PDGFD WNT10B ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 MUC5B ADAMTS5 ADAM11 ADAMTS14 ADAMTSL3 ADAMTSL4 ADAMTSL2	3.58e-20	751	76	25	M5885
Coexpression	DESCARTES_FETAL_PLACENTA_SMOOTH_MUSCLE_CELLS	SEMA5B WNT3A ADGRB1 ADAMTS18 ADAMTS20 ADAMTSL3 NOTCH3	7.40e-09	89	76	7	M40280
Coexpression	NABA_CORE_MATRISOME	FBN2 PRG3 HMCN1 SPON1 PAPLN LTBP1 LTBP3 AGRN	1.18e-06	270	76	8	MM17057
Coexpression	KATSANOU_ELAVL1_TARGETS_UP	ADAMTS10 HMCN1 POTEM ADAMTS5 POTEH POTEB NOTCH3	1.26e-06	188	76	7	MM1071
Coexpression	NABA_CORE_MATRISOME	FBN2 PRG3 HMCN1 SPON1 PAPLN LTBP1 LTBP3 AGRN	1.35e-06	275	76	8	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN2 HMCN1 SPON1 PAPLN LTBP1 LTBP3 AGRN	1.40e-06	191	76	7	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN2 HMCN1 SPON1 PAPLN LTBP1 LTBP3 AGRN	1.66e-06	196	76	7	M3008
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_PERICYTE	SEMA5B ADAMTS9 ADAMTS5 ADAMTSL3 AGRN NOTCH3	2.23e-05	195	76	6	M45684
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR	HMCN1 MEGF8 PAPLN AGRN	2.63e-05	59	76	4	M47989
Coexpression	KATSANOU_ELAVL1_TARGETS_UP	ADAMTS10 HMCN1 ADAMTS5 POTEJ NOTCH3	1.50e-04	173	76	5	M2385
Coexpression	DARWICHE_PAPILLOMA_PROGRESSION_RISK	POTEM POTEB2 POTEH POTEB	1.50e-04	92	76	4	MM503
Coexpression	NABA_BASEMENT_MEMBRANES	HMCN1 PAPLN AGRN	2.14e-04	40	76	3	M5887
Coexpression	GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP	ADAMTS12 TENM1 ADAM11 CERS1 PGK2	2.15e-04	187	76	5	M7123
Coexpression	NABA_MATRISOME_HIGHLY_METASTATIC_BREAST_CANCER	PAPLN LTBP3 AGRN	2.31e-04	41	76	3	M47988
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_1000	ADAMTS12 PAMR1 ADAMTS9 GNPTAB ADAMTS17 LTBP1 WDFY3 AGRN NOTCH3	1.02e-06	293	76	9	gudmap_kidney_P0_JuxtaGlom_Ren1_k3_1000
CoexpressionAtlas	placenta	FBN2 TIE1 ADAMTS6 ADAMTS9 WNT3A ADAMTS18 ADAMTS5 ADAMTS14 ADAMTSL4	4.27e-06	349	76	9	placenta
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1	ADAMTS12 ADAMTS10 ATRN FBN2 HMCN1 PAMR1 SEMA5B ADAMTS6 ADAMTS9 ADAMTS16 LTBP1 LMO4 RNF217 ADAMTSL2 STAB1	1.37e-05	1166	76	15	facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000	MEP1B ADAMTS12 UBR1 PAMR1 ADAMTS3 ADAMTS6 ADAMTS9 GNPTAB ADAMTS17 LTBP1 WDFY3 AGRN NOTCH3	1.78e-05	905	76	13	gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	ADAMTS12 FBN2 HMCN1 ADAMTS3 ADAMTS6 ADAMTS18 LTBP1 THSD7B	3.88e-05	354	76	8	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	ADAMTS10 FBN2 PAMR1 PAPLN LTBP1 AGRN NOTCH3	6.61e-05	281	76	7	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	ADAMTS10 FBN2 PAMR1 PAPLN LTBP1 AGRN NOTCH3	6.61e-05	281	76	7	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_StemCellamp_k-means-cluster#1_top-relative-expression-ranked_500	PRG3 HMCN1 MEGF6 ADAMTS3 ADAMTS9 ADAMTS17	6.72e-05	193	76	6	gudmap_kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_Scamp_k1_500
CoexpressionAtlas	JC_hmvEC_top-relative-expression-ranked_1000_k-means-cluster#4	CNTNAP3B STARD8 TIE1 ADAMTS6 CNTNAP3 ADAMTS18 ADAMTSL3 STAB1	1.45e-04	428	76	8	JC_hmvEC_1000_K4
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SEMA5B ADAMTS6 SPON1 PDGFD ADAMTS5 ADAMTSL3 NOTCH3 ADAMTSL2	1.52e-09	194	76	8	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 ADAMTS10 HMCN1 PAMR1 ADAMTS7 SPON1 LTBP1 ADAM11	1.58e-09	195	76	8	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS12 MEGF6 SEMA5B SPON1 PDGFD ADAMTS20 NOTCH3	2.34e-08	178	76	7	9fc5688cf705a74398d24e10e0aab4758612e72b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MEGF6 PAMR1 ADAMTS3 ADAMTS6 PDGFD LTBP1 ADAMTSL3	3.41e-08	188	76	7	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MEGF6 PAMR1 ADAMTS3 PDGFD LTBP1 ADAMTSL3 RNF217	3.80e-08	191	76	7	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MEGF6 PAMR1 ADAMTS3 SPON1 PDGFD LTBP1 ADAMTSL3	4.08e-08	193	76	7	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA5B SPON1 PDGFD ADAMTS5 ADAMTSL3 NOTCH3 ADAMTSL2	4.08e-08	193	76	7	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SEMA5B SPON1 LTBP1 ADAMTS5 ADAMTSL3 NOTCH3 ADAMTSL2	5.03e-08	199	76	7	aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B FBN2 SPON1 CNTNAP3 TENM1 ADAMTS20 THSD7B	5.21e-08	200	76	7	107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ADAMTS12 HMCN1 MEGF6 ADAMTS9 SPON1 ADAMTS20	5.67e-08	119	76	6	d8fbea9ded96fcc3ebdfb4d28873c563427ce811
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor-7\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ADAMTS12 HMCN1 MEGF6 ADAMTS9 SPON1 ADAMTS20	5.67e-08	119	76	6	9e38f13bf98b9ee44b178300e6f80fd08a006296
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATRN MEGF6 PAMR1 PDGFD PAPLN ADAMTS5	5.36e-07	174	76	6	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B PAMR1 CNTNAP3 ADAMTS17 TENM1 ADAMTS5	5.92e-07	177	76	6	4f88ea4cfcfa8a9af5a14ab6f6be3b2aa015852e
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FBN2 HMCN1 TIE1 PDGFD CNTNAP3 LTBP3	6.33e-07	179	76	6	8c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	ADAMTS12 FBN2 HMCN1 SPON1 LTBP1 ADAMTSL3	6.75e-07	181	76	6	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN2 ADAMTS3 ADAMTS9 SPON1 ADAMTS16 WDFY3	6.97e-07	182	76	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	LA-07._Pericyte\|World / Chamber and Cluster_Paper	ADAMTS12 SEMA5B ADAMTS9 THSD7B ADAMTSL3 NOTCH3	7.20e-07	183	76	6	e3835db4795362b0442d5893baf2a78efcc20428
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADAMTS17 TENM1 ADAMTS20 ADAMTS5	7.20e-07	183	76	6	d2074b13b4831ec18c81273d9a1ff673c3f6a16d
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 TIE1 SPON1 AGRN STAB1	7.20e-07	183	76	6	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 HMCN1 ADAMTS16 TENM1 ADAMTS20 MUC5B	7.43e-07	184	76	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 HMCN1 ADAMTS16 TENM1 ADAMTS20 MUC5B	7.43e-07	184	76	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 HMCN1 ADAMTS16 TENM1 ADAMTS20 MUC5B	7.43e-07	184	76	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B PAMR1 CNTNAP3 ADAMTS17 TENM1 THSD7B	7.43e-07	184	76	6	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	ADAMTS12 SEMA5B ADAMTS9 THSD7B ADAMTSL3 NOTCH3	7.67e-07	185	76	6	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADAMTS17 TENM1 ADAMTS20 ADAMTS5	7.92e-07	186	76	6	948815663c212c4311329d503b5991cbbbff9808
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN2 ADAMTS3 ADAMTS9 SPON1 ADAMTS16 WDFY3	7.92e-07	186	76	6	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FBN2 SPON1 ADAMTS17 LTBP1 LMO4 ADAMTSL3	7.92e-07	186	76	6	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ADAMTS10 ADAMTS6 LTBP3 ADAMTS5 ADAMTS14 ADAMTSL2	7.92e-07	186	76	6	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FBN2 ADAMTS6 SPON1 LTBP1 ADAMTS5 LMO4	8.17e-07	187	76	6	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	ADAMTS12 HMCN1 SPON1 ADAMTS17 ADAMTSL3 ADAMTSL2	8.17e-07	187	76	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ADAMTS10 STARD8 MEGF6 PAPLN LTBP3 THSD7B	8.43e-07	188	76	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPON1 PDGFD ADAMTS16 LMO4 AGRN ADAMTSL4	8.43e-07	188	76	6	842982de2197770f999a70083ed9fca40ac22d79
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPON1 PDGFD ADAMTS16 LMO4 AGRN ADAMTSL4	8.43e-07	188	76	6	a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 TIE1 SPON1 LMO4 STAB1	8.69e-07	189	76	6	1137583e21d874c201c20581ba1995e2bfa3de59
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ADAMTS9 CNTNAP3 TENM1 ADAMTS20 ADAMTS5	8.96e-07	190	76	6	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 TIE1 SPON1 LMO4 STAB1	8.96e-07	190	76	6	7068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MEGF6 PAMR1 ADAMTS3 ADAMTS6 LTBP1 ADAMTSL3	8.96e-07	190	76	6	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMCN1 MEGF6 TIE1 ADAMTS18 LTBP1 ADAMTS5	9.24e-07	191	76	6	fcdf3a747038e346a467eae8b7c293592658b53f
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	HMCN1 PAMR1 SPON1 TENM1 LTBP1 ADAMTSL3	9.24e-07	191	76	6	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PAMR1 PDGFD CNTNAP3 ADAMTS17 ADAMTS18 ADAMTS5	9.24e-07	191	76	6	156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	HMCN1 PAMR1 SPON1 TENM1 LTBP1 ADAMTSL3	9.24e-07	191	76	6	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PAMR1 SPON1 LTBP1 LMO4 ADAMTSL2	9.53e-07	192	76	6	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PAMR1 SPON1 LTBP1 LMO4 ADAMTSL2	9.53e-07	192	76	6	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS12 HMCN1 SPON1 ADAMTS17 LTBP1 ADAMTSL3	9.53e-07	192	76	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HMCN1 MEGF6 SEMA5B TENM1 LTBP1 NOTCH3	9.53e-07	192	76	6	a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	ADAMTS10 PAMR1 SPON1 LTBP1 ADAMTS5 ADAMTSL3	9.53e-07	192	76	6	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	15-Trachea-Endothelial-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	STARD8 HMCN1 TIE1 ADAMTS7 ADAMTS6 STAB1	9.82e-07	193	76	6	6ea0444fc3dc156997129387184e6418947f4b12
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS12 HMCN1 SPON1 LTBP1 ADAMTSL3 ADAMTSL2	9.82e-07	193	76	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	15-Trachea-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	STARD8 HMCN1 TIE1 ADAMTS7 ADAMTS6 STAB1	9.82e-07	193	76	6	b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCell	facs-Pancreas-Exocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS9 SPON1 PDGFD ADAMTS16 AGRN ADAMTSL4	9.82e-07	193	76	6	c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS12 HMCN1 ADAMTS16 LTBP1 ADAMTS14 NOTCH3	9.82e-07	193	76	6	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PAMR1 ADAMTS3 LTBP1 ADAMTS5 ADAMTSL3 RNF217	9.82e-07	193	76	6	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADAMTS17 TENM1 ADAMTS20 ADAMTS5	1.01e-06	194	76	6	e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 TIE1 SPON1 LMO4 STAB1	1.04e-06	195	76	6	df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PAMR1 ADAMTS3 LTBP1 ADAMTSL3 ADAMTSL2	1.04e-06	195	76	6	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTS12 HMCN1 SPON1 LTBP1 ADAMTSL3 ADAMTSL2	1.04e-06	195	76	6	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PAMR1 SPON1 LTBP1 LMO4 ADAMTSL2	1.07e-06	196	76	6	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MEGF8 ADAMTS9 CNTNAP3 TENM1 LTBP3 ADAMTS14	1.07e-06	196	76	6	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PAMR1 SPON1 LTBP1 LMO4 ADAMTSL2	1.07e-06	196	76	6	ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PAMR1 SPON1 LTBP1 LMO4 ADAMTSL2	1.07e-06	196	76	6	30ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PAMR1 SPON1 LTBP1 LMO4 ADAMTSL2	1.07e-06	196	76	6	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FBN2 PAMR1 SEMA5B ADAMTS16 ADAMTSL3 ADAMTSL4	1.07e-06	196	76	6	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS12 HMCN1 SPON1 ADAMTS17 LTBP1 ADAMTSL3	1.07e-06	196	76	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMCN1 TIE1 ADAMTS9 CNTNAP3 ADAMTS18 STAB1	1.11e-06	197	76	6	4e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS10 HMCN1 ADAMTS16 CERS1 LCMT2 ADAMTSL2	1.14e-06	198	76	6	7d2fe57e0f9311ac1e6854402ebc154306eb1ba5
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SEMA5B ADAMTS9 SPON1 ADAMTS5 ADAMTSL3 NOTCH3	1.14e-06	198	76	6	76d46950c11cb4708866db0da54ce00d5c0adab8
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PAMR1 SPON1 WNT10B ADAMTS16 LTBP1 ADAMTS5	1.17e-06	199	76	6	4e128c705ad36fd840582848f278770f356fcc8b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PAMR1 SPON1 WNT10B ADAMTS16 LTBP1 ADAMTS5	1.17e-06	199	76	6	4032f03a4165f5f2a90ef1d8315cc743ce9075bb
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PAMR1 SPON1 WNT10B ADAMTS16 LTBP1 ADAMTS5	1.21e-06	200	76	6	8d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PENK-L1-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FBN2 ADAMTS6 ADAMTS17 PAPLN THSD7B PGK2	1.21e-06	200	76	6	08a00b0687bef5fef12bfa8e52ae4570071bae5e
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	ADAMTS12 PAMR1 LTBP1 LTBP3 ADAMTS5 ADAMTSL3	1.21e-06	200	76	6	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PENK\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FBN2 ADAMTS6 ADAMTS17 PAPLN THSD7B PGK2	1.21e-06	200	76	6	266990ee2e835e98b92dfdf7e3114f9737ffa85e
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 HMCN1 SPON1 ADAMTS17 ADAMTSL3 ADAMTSL2	1.21e-06	200	76	6	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 HMCN1 PAMR1 SPON1 ADAMTS16 LTBP1	1.21e-06	200	76	6	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-1\|TCGA-Thryoid / Sample_Type by Project: Shred V9	RETN HMCN1 ADAMTS6 SPON1 ADAMTS14	7.12e-06	156	76	5	45a05c7a45a3ec8551818ab67f18b3b9553934c1
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 SPON1 ADAMTS20 MUC5B THSD7B	7.57e-06	158	76	5	b70b4dbcb0ee96d98578c14e89b1c3f74e84c517
ToppCell	21-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	HMCN1 ADAMTS9 ADGRB1 ADAMTS18 THSD7B	7.81e-06	159	76	5	4f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCell	NS-critical-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TIE1 ADAMTS3 ADAMTS7 ADAMTS14 STAB1	8.05e-06	160	76	5	c61869d9dbba250270e59366e15af204e5b4395d
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS6 LTBP1 LTBP3 ADAMTS5 THSD7B	9.07e-06	164	76	5	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 CNTNAP3B PAMR1 CNTNAP3 ADAMTS5	9.35e-06	165	76	5	2d01ae5d05fe55f6bebd53a5801c4c1f1544515c
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	ADAMTS12 SPON1 ADAMTS16 ADAMTS14 STAB1	1.02e-05	168	76	5	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS12 PAMR1 SPON1 LTBP1 NOTCH3	1.02e-05	168	76	5	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS12 PAMR1 SPON1 LTBP1 NOTCH3	1.02e-05	168	76	5	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 TIE1 ADAMTS17 STAB1	1.02e-05	168	76	5	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 TIE1 ADAMTS17 STAB1	1.02e-05	168	76	5	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 ADAMTS6 ADAMTS17 PAPLN THSD7B	1.05e-05	169	76	5	eb3b8e473192c4b8688f2f8da400116dd6fe193d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRB1 ADAMTS18 PAPLN ADAMTSL3 NOTCH3	1.08e-05	170	76	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADAMTS17 TENM1 ADAMTS5	1.24e-05	175	76	5	11f49f00e000cbc137e3540a6d6805cde21d96e6
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FBN2 HMCN1 PDGFD CNTNAP3 LTBP3	1.28e-05	176	76	5	52af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS6 LTBP1 LTBP3 ADAMTS5 THSD7B	1.31e-05	177	76	5	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B PAMR1 CNTNAP3 ADAMTS17 ADAMTS5	1.31e-05	177	76	5	4d67e24653caa318039870114849426ff2582e0c
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1S SEMA5B ADAMTS9 AGRN NOTCH3	1.35e-05	178	76	5	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS3 SPON1 WNT10B LTBP1 ADAMTSL2	1.35e-05	178	76	5	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS3 SPON1 WNT10B LTBP1 ADAMTSL2	1.35e-05	178	76	5	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADAMTS17 TENM1 ADAMTS5	1.35e-05	178	76	5	c982a73955c9c193bcab21d60d453afcc09cd586
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B TIE1 ADAMTS6 ADAMTS9 PDGFD	1.39e-05	179	76	5	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS12 HMCN1 ADAMTS16 PAPLN ADAMTS14	1.42e-05	180	76	5	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADAMTS17 TENM1 ADAMTS5	1.42e-05	180	76	5	8f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS12 HMCN1 ADAMTS16 PAPLN ADAMTS14	1.42e-05	180	76	5	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP1 ADAMTS5 ADAMTS14 NOTCH3 STAB1	1.42e-05	180	76	5	79c5725f02e038d0187f4a1e1591f2492538aa57
Drug	tegafur	ADAMTS12 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS20 ADAMTS14	1.30e-08	49	75	6	CID000005386
Drug	chondroitin sulfate	ADAMTS12 ADAMTS3 SEMA5B ADAMTS7 ADAMTS9 ADAMTS16 ADAMTS18 LTBP1 ADAMTS5 AGRN ADAMTSL4	1.06e-07	413	75	11	CID000024766
Drug	Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A	MEGF6 ADAMTS9 ADGRB1 TENM1 ADAMTS20 ADAMTS5 WDFY3	4.35e-06	200	75	7	3167_UP
Drug	4-Arsono-2-hydroxybutanoic acid	PGK1 PGK2	1.07e-05	2	75	2	CID000135804
Drug	funiferine N-oxide	FBN2 LTBP1 LTBP3 AGRN	2.06e-05	49	75	4	CID000191631
Drug	Dirian	PGK1 PGK2	3.21e-05	3	75	2	CID003034337
Drug	AC1NDNJY	PGK1 PGK2	3.21e-05	3	75	2	CID004578722
Drug	AC1O5U9L	PGK1 PGK2	3.21e-05	3	75	2	CID006440811
Disease	carpal tunnel syndrome	ADAMTS10 ADAMTS17 LTBP1 ADAMTS14 ADAMTSL2	2.48e-06	89	71	5	EFO_0004143
Disease	glycerate measurement	HMCN1 THSD7B AGRN	5.95e-06	15	71	3	EFO_0021029
Disease	Weill-Marchesani syndrome (implicated_via_orthology)	ADAMTS10 ADAMTS17	1.71e-05	3	71	2	DOID:0050475 (implicated_via_orthology)
Disease	cortical surface area measurement, neuroimaging measurement	MEGF6 ADAMTS3 ADAMTS9 PDGFD ADAMTS18 ADAMTS20	1.83e-05	227	71	6	EFO_0004346, EFO_0010736
Disease	Weill-Marchesani syndrome	ADAMTS10 ADAMTS17	3.41e-05	4	71	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	ADAMTS10 ADAMTS17	3.41e-05	4	71	2	DOID:0050475 (is_implicated_in)
Disease	Geleophysic dysplasia	LTBP3 ADAMTSL2	5.68e-05	5	71	2	C3489726
Disease	Acromicric Dysplasia	LTBP3 ADAMTSL2	5.68e-05	5	71	2	C0265287
Disease	central corneal thickness	FBN2 ADAMTS6 ADAMTS17 ADAMTS18 ADAMTS20 LTBP1	1.02e-04	309	71	6	EFO_0005213
Disease	body fat distribution	ADAMTS10 ADAMTS3 ADAMTS17 ADAMTS14 ADAMTSL3	1.29e-04	202	71	5	EFO_0004341
Disease	corneal topography	ADAMTS3 ADAMTS7 ADAMTS6 ADAMTS20	1.41e-04	109	71	4	EFO_0004345
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	1.58e-04	8	71	2	DOID:0060308 (implicated_via_orthology)
Disease	osteosarcoma	ADAMTS6 ADAMTS17	1.58e-04	8	71	2	EFO_0000637
Disease	smoking behavior, BMI-adjusted waist circumference	ADAMTS3 ADAMTS17 LTBP1 ADAMTSL3	2.18e-04	122	71	4	EFO_0004318, EFO_0007789
Disease	intraocular pressure measurement	FBN2 ADAMTS6 ADAMTS17 ADAMTS18 ADAMTS20 LTBP1 LTBP3	2.24e-04	509	71	7	EFO_0004695
Disease	Colorectal Carcinoma	FBN2 STARD8 EFS PDGFD TENM1 ADAMTS18 ADAMTSL3 CAPN10	2.80e-04	702	71	8	C0009402
Disease	stenosing tenosynovitis	ADAMTS6 LTBP3	3.71e-04	12	71	2	EFO_0010822
Disease	tyrosine-protein kinase receptor Tie-1, soluble measurement	TIE1 ADAMTSL2	4.38e-04	13	71	2	EFO_0008312
Disease	Hypodontia	WNT10B LTBP3	5.10e-04	14	71	2	C0020608
Disease	vital capacity	ADAMTS10 CACNA1S HMCN1 ADAMTS3 ADAMTS6 ADAMTS17 ADAMTS18 LTBP1 LTBP3 ADAMTSL3	7.25e-04	1236	71	10	EFO_0004312
Disease	severe acute respiratory syndrome, COVID-19	ADAMTS12 TMPRSS13 MEGF6 SEMA5B ADAMTS17 LTBP3	7.29e-04	447	71	6	EFO_0000694, MONDO_0100096
Disease	anthropometric measurement	ADAMTS3 LTBP3 ADAMTS5 ADAMTSL3	7.32e-04	168	71	4	EFO_0004302
Disease	corneal resistance factor	FBN2 ADAMTS6 ADAMTS17 ADAMTS18 ADAMTS20 LTBP1	7.64e-04	451	71	6	EFO_0010067
Disease	body weight	ADAMTS10 FBN2 ADAMTS3 ADAMTS17 LTBP1 LTBP3 THSD7B ADAMTS14 ADAMTSL3 PGK1	8.45e-04	1261	71	10	EFO_0004338
Disease	body surface area	ADAMTS10 FBN2 ADAMTS3 ADAMTS17 LTBP1 LTBP3 ADAMTSL3	8.99e-04	643	71	7	EFO_0022196
Disease	urinary albumin to creatinine ratio	CACNA1S PDGFD THSD7B STAB1	9.27e-04	179	71	4	EFO_0007778
Disease	tooth agenesis	CACNA1S THSD7B	1.28e-03	22	71	2	EFO_0005410
Disease	cortical thickness	FBN2 ADAMTS3 ADAMTS7 ADAMTS9 WNT3A ADAMTS18 ADAMTS20 ADAMTSL3 STAB1	1.37e-03	1113	71	9	EFO_0004840
Disease	cortical surface area measurement	FBN2 MEGF6 ADAMTS3 ADAMTS7 EFS ADAMTS9 PDGFD ADAMTS18 ADAMTS20 ADAMTSL3	1.37e-03	1345	71	10	EFO_0010736
Disease	obesity (is_implicated_in)	RETN WNT10B CAPN10	1.39e-03	91	71	3	DOID:9970 (is_implicated_in)
Disease	lobe attachment	CACNA1S HMCN1 ADAMTS18 ADAMTS14	1.58e-03	207	71	4	EFO_0007667
Disease	osteoarthritis (is_implicated_in)	ADAMTS5 ADAMTS14	2.07e-03	28	71	2	DOID:8398 (is_implicated_in)
Disease	type 2 diabetes mellitus (implicated_via_orthology)	ADAMTS9 ADAMTS20 CAPN10	2.10e-03	105	71	3	DOID:9352 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DLGCACRWGGTTGTV	DCAF17	251	Q5H9S7
SWGGSLPDAQKCTCG	CNTNAP3	711	Q9BZ76
VGHSACSASCGKGVW	ADAMTSL4	671	Q6UY14
WGSCSVTCGAGSQRR	ADGRB1	531	O14514
WGQCSRSCGGGVQFA	ADAMTS5	576	Q9UNA0
GGTCQDWALGGGFTC	AGRN	1341	O00468
CGRKGSGWVQCSKQD	ADAM11	581	O75078
WVKGQSAGGCRNNSG	CAPN10	346	Q9HC96
WGDCSRTCGGGVSSS	ADAMTS10	556	Q9H324
GNWSECSVSCGGGVR	ADAMTS12	951	P58397
GNWSKCSRNCSGGFK	ADAMTS12	1371	P58397
ATGNWDLCSTSCGGG	ADAMTS12	1476	P58397
SSWTKFGSCSRSCGG	ADAMTS14	556	Q8WXS8
WGACSRSCGKLGVQT	ADAMTS14	916	Q8WXS8
WSACSRTCGGGAQSR	ADAMTS16	936	Q8TE57
HSGWEGCSVQCGGGE	ADAMTS17	806	Q8TE56
SKWSECSRTCGGGVK	ADAMTS18	596	Q8TE60
NWGECSQTCGGGIKS	ADAMTS20	1366	P59510
LWGECSRTCGGGVSS	ADAMTS6	566	Q9UKP5
VDGTRCGENKWCLSG	ADAMTS7	511	Q9UKP4
WSKCSRSCGGGSSVR	ADAMTS7	1471	Q9UKP4
RGVCSDWRGATGGLC	MUC5B	5341	Q9HC84
IGGGDTATCCAKWNT	PGK2	371	P07205
CCRGSGKSNVGTWGD	POTEB2	71	H3BUK9
CDWDGGDCSGNSGGS	GNPTAB	461	Q3T906
GSLSWKRCAGCGGKI	LMO4	16	P61968
GCGWCTDPSNTGKGK	ATRN	1001	O75882
QGWAEGQGLGCRCSG	GPATCH3	421	Q96I76
RCGGNCGCGTVNWRS	PDGFD	301	Q9GZP0
SKQEDCCGTVGTSWG	LTBP1	576	Q14766
ACPGCSTGGARSWKV	PDCD2L	81	Q9BRP1
GGHSCVCVNGWTGES	NOTCH3	296	Q9UM47
NCTSCLDSKGADGGW	MEGF8	2066	Q7Z7M0
WTACSRSCGGGVTSQ	ADAMTSL2	56	Q86TH1
WGPCSGSCGQGRTIR	ADAMTSL2	746	Q86TH1
SWAGSRQGSKECPGC	NSMF	156	Q6X4W1
IGGGDTATCCAKWNT	PGK1	371	P00558
PWGTCSESCGKGTQT	HMCN1	4651	Q96RW7
HSWSQCSASCGGGEK	HMCN1	4821	Q96RW7
GQGSCVALCTKGGYW	PRG3	196	Q9Y2Y8
SWTKFGSCSRTCGTG	ADAMTS3	556	O15072
KCSGECNTGGWRYSA	ADAMTS9	991	Q9P2N4
PWGACSSTCAGGSQR	ADAMTS9	1336	Q9P2N4
WGECTKLCGGGIRTR	ADAMTS9	1391	Q9P2N4
RINGKWSGQSAGGCG	CAPN7	691	Q9Y6W3
GRRCTINGSECRGGW	CACNA1S	251	Q13698
GCTDCGWGLARRGLA	CERS1	36	P27544
QREGAGGLDGWCLCS	EFS	36	O43281
EDCCGSIGTAWGQSK	LTBP3	301	Q9NS15
TKSECCCDGGRGWGH	FBN2	2406	P35556
TARCCGELWATGSKG	CELSR3	201	Q9NYQ7
GKGWRMDGGRTCSCS	FAM30A	76	Q9NZY2
WNADGSASCVRCGNG	C1orf159	91	Q96HA4
GSGCWSSVGNRRVGK	MEP1B	121	Q16820
RGLCRAWGGTCGAAL	ECSIT	11	Q9BQ95
SWGGSLPDAQKCTCG	CNTNAP3B	711	Q96NU0
CKSCRNGSWGGTLDD	PAMR1	91	Q6UXH9
SNGSCSCGLGWTGRH	MEGF6	1316	O75095
TAWSECTKLCGGGIQ	SPON1	761	Q9HCB6
CCRGSGKSNVGTWGD	POTEB	71	A0A0A6YYL3
GLCTETGCRCDAGWT	NAGPA	371	Q9UK23
TGCRCDAGWTGSNCS	NAGPA	376	Q9UK23
CCRGSGKSNVGAWGD	POTEJ	71	P0CG39
KGECHCSTGWGGVNC	TENM1	641	Q9UKZ4
SGGGCGSDWGCADTS	RNF217	51	Q8TC41
WGCEGRRGSCGSTGS	STARD8	256	Q92502
RWSGGSQTRCGKCVK	nan	101	Q8N2B8
AGVTSWGTGCGQRNK	TMPRSS13	526	Q9BYE2
WVKDEGGDSCSGCSV	WDFY3	3451	Q8IZQ1
WAPCSASCGGGSQSR	PAPLN	371	O95428
GTWGLCSKSCSSGTR	PAPLN	491	O95428
CSCGSGWRGSQCQEA	TIE1	291	P35590
CGGCGSCGDREWLRA	TMEM79	186	Q9BSE2
GGFCDCGDTEAWKTG	UBR1	146	Q8IWV7
GDGSCVCNVGWQGLR	STAB1	1396	Q9NY15
WSKCSSNCGGGMQSR	SEMA5B	731	Q9P283
SLGEECWSLGQCGGV	VPS13B	1386	Q7Z7G8
CGCSSRHQGSPGKGW	WNT3A	136	P56704
SCGWCQKTPADGGSV	ZBTB10	271	Q96DT7
LVSCGCGWKGSGEQD	WNT10B	141	O00744
LGNWSACKLEGGDCG	THSD7B	1306	Q9C0I4
CDSEWKGSQIGSCGT	LCMT2	396	O60294
WQGCLRKSCGIAGGD	XKR5	326	Q6UX68
GCTCGSACGSWDVRA	RETN	71	Q9HD89
CFAWCRGSGKSNVGT	POTEH	31	Q6S545
WCRGSGKSNVGTSGD	POTEH	71	Q6S545
WCRGSGKSNVGTSGD	POTEM	71	A6NI47
GDWSKCSVSCGVGIQ	ADAMTSL3	826	P82987