Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	modification-dependent protein binding	ANK2 ANK3 L3MBTL2 ZMYND8 PEX1 PHF8 ZZZ3 KMT2A	9.25e-06	206	100	8	GO:0140030
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2B KMT2A KDM2A	1.43e-05	10	100	3	GO:0045322
GeneOntologyMolecularFunction	histone modifying activity	KMT2B PHF8 SRCAP BAZ1A SETBP1 HASPIN KMT2A KDM2A	1.99e-05	229	100	8	GO:0140993
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2B SETBP1 KMT2A	1.31e-04	20	100	3	GO:0042800
GeneOntologyMolecularFunction	structural molecule activity	MRPS31 MXRA5 ANK2 ANK3 ABI3BP OBSCN NUP98 DAG1 ERVK-7 MRPL45 NPHP4 MRPL14 BSN MUC5AC	1.39e-04	891	100	14	GO:0005198
GeneOntologyMolecularFunction	histone H3K36me/H3K36me2 demethylase activity	PHF8 KDM2A	1.48e-04	4	100	2	GO:0140680
GeneOntologyMolecularFunction	lysine-acetylated histone binding	ZMYND8 ZZZ3 KMT2A	4.48e-04	30	100	3	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	ZMYND8 ZZZ3 KMT2A	4.95e-04	31	100	3	GO:0140033
GeneOntologyMolecularFunction	transcription coregulator activity	RRP1B ZMYND8 NUP98 SUPT20HL2 KCTD1 PHF8 SRCAP LDB2 RALY KDM2A	5.15e-04	562	100	10	GO:0003712
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	ANK2 ANK3 RRP1B ZMYND8 NUP98 PEX1 SUPT20HL2 KCTD1 PHF8 SRCAP LDB2 RALY FZR1 ZZZ3 KDM2A	6.40e-04	1160	100	15	GO:0030674
GeneOntologyMolecularFunction	spectrin binding	ANK2 ANK3 DMTN	6.52e-04	34	100	3	GO:0030507
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2B KMT2A	6.82e-04	8	100	2	GO:0140945
GeneOntologyMolecularFunction	methylated histone binding	L3MBTL2 ZMYND8 PHF8 ZZZ3	9.18e-04	86	100	4	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	L3MBTL2 ZMYND8 PHF8 ZZZ3	1.00e-03	88	100	4	GO:0140034
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK2 ANK3	1.09e-03	10	100	2	GO:0140031
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2B KMT2A	1.09e-03	10	100	2	GO:0140999
GeneOntologyMolecularFunction	molecular adaptor activity	ANK2 ANK3 RRP1B ZMYND8 NUP98 PEX1 SUPT20HL2 KCTD1 PHF8 SRCAP DCTN1 LDB2 RALY FZR1 ZZZ3 KDM2A	1.11e-03	1356	100	16	GO:0060090
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF18A ANK2 ANK3 ABI3BP OBSCN DAG1 KIF4A SPIRE1 DCTN1 LMOD2 PTPRT INF2 REEP4 DMTN	1.14e-03	1099	100	14	GO:0008092
GeneOntologyMolecularFunction	histone H3K36 demethylase activity	PHF8 KDM2A	1.33e-03	11	100	2	GO:0051864
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2B SETBP1 KMT2A	1.39e-03	44	100	3	GO:0140938
GeneOntologyMolecularFunction	histone binding	L3MBTL2 ZMYND8 PHF8 SRCAP ZZZ3 KMT2A	2.17e-03	265	100	6	GO:0042393
GeneOntologyCellularComponent	asymmetric synapse	ANK2 ANK3 ABI3BP SH3GL3 ADGRB1 PAK6 CHRM2 PTPRT BSN DMTN	1.24e-04	477	103	10	GO:0032279
GeneOntologyCellularComponent	costamere	ANK2 ANK3 DAG1	1.67e-04	22	103	3	GO:0043034
GeneOntologyCellularComponent	neuron to neuron synapse	ANK2 ANK3 ABI3BP SH3GL3 ADGRB1 PAK6 CHRM2 PTPRT BSN DMTN	2.60e-04	523	103	10	GO:0098984
GeneOntologyCellularComponent	postsynaptic density	ANK2 ANK3 ABI3BP SH3GL3 ADGRB1 PAK6 PTPRT BSN DMTN	3.91e-04	451	103	9	GO:0014069
GeneOntologyCellularComponent	M band	ANK2 OBSCN LMOD2	4.72e-04	31	103	3	GO:0031430
GeneOntologyCellularComponent	ribbon synapse	DAG1 NPHP4 BSN	5.19e-04	32	103	3	GO:0097470
GeneOntologyCellularComponent	MLL1/2 complex	KMT2B KANSL1 KMT2A	5.69e-04	33	103	3	GO:0044665
GeneOntologyCellularComponent	male pronucleus	CCNA2 TET3	6.60e-04	8	103	2	GO:0001940
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	ANK3 DMTN	8.46e-04	9	103	2	GO:0014731
GeneOntologyCellularComponent	postsynaptic specialization	ANK2 ANK3 ABI3BP SH3GL3 ADGRB1 PAK6 PTPRT BSN DMTN	8.54e-04	503	103	9	GO:0099572
GeneOntologyCellularComponent	female pronucleus	CCNA2 TET3	1.05e-03	10	103	2	GO:0001939
GeneOntologyCellularComponent	postsynapse	ANK2 ANK3 ABI3BP HTR7 SH3GL3 ZMYND8 ADGRB1 DAG1 PAK6 CHRM2 PTPRT BSN DMTN	1.48e-03	1018	103	13	GO:0098794
HumanPheno	Generalized hypertrichosis	SRCAP SETBP1 KMT2A	6.35e-06	7	30	3	HP:0004554
Domain	Znf_FYVE_PHD	KMT2B ZMYND8 SPIRE1 PHF8 BAZ1A KMT2A KDM2A BSN FGD6	7.86e-08	147	98	9	IPR011011
Domain	Znf_PHD-finger	KMT2B ZMYND8 PHF8 BAZ1A KMT2A KDM2A	3.65e-06	79	98	6	IPR019787
Domain	PHD	KMT2B ZMYND8 PHF8 BAZ1A KMT2A KDM2A	7.31e-06	89	98	6	SM00249
Domain	Znf_PHD	KMT2B ZMYND8 PHF8 BAZ1A KMT2A KDM2A	8.32e-06	91	98	6	IPR001965
Domain	ZF_PHD_2	KMT2B ZMYND8 PHF8 BAZ1A KMT2A KDM2A	1.07e-05	95	98	6	PS50016
Domain	ZF_PHD_1	KMT2B ZMYND8 PHF8 BAZ1A KMT2A KDM2A	1.13e-05	96	98	6	PS01359
Domain	AT_hook	KMT2B SRCAP SETBP1 KMT2A	1.14e-05	27	98	4	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2B SRCAP SETBP1 KMT2A	1.14e-05	27	98	4	IPR017956
Domain	Znf_CXXC	KMT2B KMT2A KDM2A	2.24e-05	11	98	3	IPR002857
Domain	ZF_CXXC	KMT2B KMT2A KDM2A	2.24e-05	11	98	3	PS51058
Domain	zf-CXXC	KMT2B KMT2A KDM2A	2.24e-05	11	98	3	PF02008
Domain	MeTrfase_trithorax	KMT2B KMT2A	2.73e-05	2	98	2	IPR016569
Domain	PHD	KMT2B ZMYND8 PHF8 BAZ1A KMT2A	4.63e-05	75	98	5	PF00628
Domain	WH2	SPIRE1 LMOD2 INF2	2.62e-04	24	98	3	PS51082
Domain	FYrich_C	KMT2B KMT2A	2.70e-04	5	98	2	IPR003889
Domain	FYrich_N	KMT2B KMT2A	2.70e-04	5	98	2	IPR003888
Domain	FYRC	KMT2B KMT2A	2.70e-04	5	98	2	SM00542
Domain	FYRN	KMT2B KMT2A	2.70e-04	5	98	2	SM00541
Domain	FYRN	KMT2B KMT2A	2.70e-04	5	98	2	PF05964
Domain	FYRC	KMT2B KMT2A	2.70e-04	5	98	2	PF05965
Domain	FYRC	KMT2B KMT2A	2.70e-04	5	98	2	PS51543
Domain	FYRN	KMT2B KMT2A	2.70e-04	5	98	2	PS51542
Domain	Zinc_finger_PHD-type_CS	ZMYND8 PHF8 BAZ1A KDM2A	3.78e-04	65	98	4	IPR019786
Domain	-	KMT2B ZMYND8 SPIRE1 PHF8 BAZ1A KMT2A KDM2A BSN FGD6	5.88e-04	449	98	9	3.30.40.10
Domain	Znf_RING/FYVE/PHD	KMT2B ZMYND8 SPIRE1 PHF8 BAZ1A KMT2A KDM2A BSN FGD6	6.88e-04	459	98	9	IPR013083
Domain	ZU5	ANK2 ANK3	9.58e-04	9	98	2	SM00218
Domain	ZU5	ANK2 ANK3	1.19e-03	10	98	2	PS51145
Domain	BROMODOMAIN_2	ZMYND8 BAZ1A KMT2A	1.29e-03	41	98	3	PS50014
Domain	BROMO	ZMYND8 BAZ1A KMT2A	1.39e-03	42	98	3	SM00297
Domain	Bromodomain	ZMYND8 BAZ1A KMT2A	1.39e-03	42	98	3	IPR001487
Domain	-	ZMYND8 BAZ1A KMT2A	1.39e-03	42	98	3	1.20.920.10
Domain	ZU5	ANK2 ANK3	1.74e-03	12	98	2	PF00791
Domain	ZU5_dom	ANK2 ANK3	1.74e-03	12	98	2	IPR000906
Domain	Post-SET_dom	KMT2B KMT2A	3.12e-03	16	98	2	IPR003616
Domain	PostSET	KMT2B KMT2A	3.12e-03	16	98	2	SM00508
Domain	AT_hook	SETBP1 KMT2A	3.12e-03	16	98	2	PF02178
Domain	POST_SET	KMT2B KMT2A	3.12e-03	16	98	2	PS50868
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2B ZZZ3 KANSL1 KMT2A	4.05e-05	38	72	4	MM17073
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2B ZZZ3 KANSL1 KMT2A	6.05e-05	42	72	4	M48018
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SRRM1 KMT2B L3MBTL2 RRP1B TLX3 ZMYND8 NUP98 GATA6 KIF4A PHF8 SRCAP RALY ZZZ3 KANSL1 BAZ1A KMT2A KDM2A REEP4 TET3	9.10e-09	1294	104	19	30804502
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	KMT2B KMT2A KDM2A TET3	1.56e-08	10	104	4	29276034
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TPRA1 KMT2B OBSCN SPIRE1 TOR4A SRCAP NPHP4 DCTN1 FZR1 TNRC18 KANSL1 TULP4 INF2 PI4KA SBF2 DIP2C	1.87e-07	1105	104	16	35748872
Pubmed	Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein.	SH3GL3 SH3D19 KMT2A	2.59e-07	5	104	3	14551139
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK2 ANK3 DAG1	2.59e-07	5	104	3	19109891
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SRRM1 KMT2B L3MBTL2 RRP1B PIGK KIF4A MCM10 PHF8 SRCAP BAZ1A KMT2A KDM2A	2.93e-07	608	104	12	36089195
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	MRPS31 SRRM1 ANK2 RRP1B TROAP ID4 SSB PHF8 USP37 DCTN1 CCNA2 FZR1 KANSL1 MRPL14	1.23e-06	971	104	14	33306668
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	L3MBTL2 ZMYND8 NUP98 ID4 KIF4A MRPL45 DCTN1 LDB2 RALY KANSL1 BAZ1A PI4KA KDM2A	1.75e-06	857	104	13	25609649
Pubmed	Gene expression and cell identity controlled by anaphase-promoting complex.	KIF18A GATA6 CCNA2 FZR1 KMT2A	1.95e-06	68	104	5	32076268
Pubmed	Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.	USP37 CCNA2 FZR1	2.15e-06	9	104	3	21596315
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SRRM1 RRP1B ZMYND8 KIF4A SSB SRCAP DCTN1 BAZ1A KMT2A	2.99e-06	394	104	9	27248496
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	SRRM1 KMT2B PEX1 KIF4A SPIRE1 SSB SRCAP DCTN1 ZZZ3 INF2	2.99e-06	506	104	10	30890647
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ANK3 SH3GL3 CYP27B1 OBSCN GATA6 PEX1 DAG1 SPIRE1 SRCAP DCTN1 INF2 BAZ1A PI4KA SBF2	4.40e-06	1084	104	14	11544199
Pubmed	Human transcription factor protein interaction networks.	MRPS31 KMT2B L3MBTL2 RRP1B TLX3 ZMYND8 NUP98 GATA6 ID4 SSB PHF8 SRCAP CCNA2 ZZZ3 KANSL1 KMT2A	5.32e-06	1429	104	16	35140242
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2B ANK3 KIF4A PHF8 SRCAP DCTN1 ZZZ3 SH3D19 KMT2A KDM2A	6.13e-06	549	104	10	38280479
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	PTPRT PI4KA KMT2A KDM2A TET3	7.79e-06	90	104	5	15033168
Pubmed	KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.	KMT2B KMT2A	8.86e-06	2	104	2	28723559
Pubmed	MLL4 binds TET3.	KMT2B TET3	8.86e-06	2	104	2	38579707
Pubmed	Specificity of MLL1 and TET3 CXXC domains towards naturally occurring cytosine modifications.	KMT2A TET3	8.86e-06	2	104	2	30352306
Pubmed	A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division.	SPIRE1 INF2	8.86e-06	2	104	2	26305500
Pubmed	NUP98-MLL fusion in human acute myeloblastic leukemia.	NUP98 KMT2A	8.86e-06	2	104	2	20558618
Pubmed	Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation.	DCTN1 CEP126	8.86e-06	2	104	2	24867236
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	8.86e-06	2	104	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	8.86e-06	2	104	2	25383926
Pubmed	NEK5 promotes breast cancer cell proliferation through up-regulation of Cyclin A2.	CCNA2 NEK5	8.86e-06	2	104	2	30675923
Pubmed	Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size.	SYNJ2 PI4KA	8.86e-06	2	104	2	24077433
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TPRA1 ANK3 OBSCN SPIRE1 RALY TNRC18 TULP4 SYNJ2 INF2 SBF2 SETBP1 CDK5RAP1 DIP2C KDM2A TET3 PDZD2	8.90e-06	1489	104	16	28611215
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	L3MBTL2 TROAP NUP98 KIF4A SSB DCTN1 CCNA2 RALY NBAS FZR1 KANSL1 SYNJ2 INF2 SH3D19	9.04e-06	1155	104	14	20360068
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MRPS31 SRRM1 RRP1B NUP98 PEX1 SPIRE1 SSB MRPL45 CHRM2 RALY NBAS MRPL14 INF2 PI4KA SH3D19 CDK5RAP1	9.44e-06	1496	104	16	32877691
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	L3MBTL2 KIF4A TOR4A MCM10 PHF8 SRCAP DCTN1 RALY KANSL1 MRPL14 INF2 BAZ1A PI4KA KDM2A PRR14L	1.21e-05	1353	104	15	29467282
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KMT2B PHF8 KMT2A KDM2A	1.44e-05	49	104	4	34368113
Pubmed	A human MAP kinase interactome.	ANK3 ABI3BP NUP98 PAK6 DCTN1 KANSL1 SYNJ2 SH3D19 KDM2A	1.60e-05	486	104	9	20936779
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP37 NPHP4 TMEM200A TNRC18 TULP4 SBF2 DIP2C KDM2A FGD6	1.79e-05	493	104	9	15368895
Pubmed	SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.	SRRM1 ZMYND8 INF2	2.05e-05	18	104	3	29996942
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	KMT2B NUP98 MRPL45 TNRC18 KMT2A	2.07e-05	110	104	5	26841866
Pubmed	Function of Nup98 subtypes and their fusion proteins, Nup98-TopIIβ and Nup98-SETBP1 in nuclear-cytoplasmic transport.	NUP98 SETBP1	2.65e-05	3	104	2	28392395
Pubmed	NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.	NUP98 KMT2A	2.65e-05	3	104	2	27889185
Pubmed	MLL is essential for NUP98-HOXA9-induced leukemia.	NUP98 KMT2A	2.65e-05	3	104	2	28210005
Pubmed	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.	ANK2 OBSCN	2.65e-05	3	104	2	12527750
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	2.65e-05	3	104	2	15611082
Pubmed	Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs.	PHF8 KDM2A	2.65e-05	3	104	2	39273051
Pubmed	The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML.	NUP98 KMT2A	2.65e-05	3	104	2	34582559
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	2.65e-05	3	104	2	33410423
Pubmed	A PIK3C3-ankyrin-B-dynactin pathway promotes axonal growth and multiorganelle transport.	ANK2 DCTN1	2.65e-05	3	104	2	25533844
Pubmed	Deubiquitinase DUB3 Regulates Cell Cycle Progression via Stabilizing Cyclin A for Proliferation of Non-Small Cell Lung Cancer Cells.	USP17L2 CCNA2	2.65e-05	3	104	2	30935108
Pubmed	Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.	ANK2 OBSCN	2.65e-05	3	104	2	18782775
Pubmed	Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment.	KIF18A KIF4A	2.65e-05	3	104	2	35926461
Pubmed	The HBx oncoprotein of hepatitis B virus deregulates the cell cycle by promoting the intracellular accumulation and re-compartmentalization of the cellular deubiquitinase USP37.	USP37 FZR1	2.65e-05	3	104	2	25347529
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	2.65e-05	3	104	2	34289389
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2B KMT2A KDM2A	3.32e-05	21	104	3	27626377
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	SRRM1 CENPL SSB NPHP4 PTPRT ZZZ3 ARHGAP29 REEP4	3.97e-05	420	104	8	28065597
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MRPS31 KIF18A CLUAP1 ANK3 RRP1B SPIRE1 SSB NPHP4 DCTN1 NEK5 REEP4 FGD6 MUC5AC DYRK2	3.98e-05	1321	104	14	27173435
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	KIF18A RRP1B NUP98 KIF4A HASPIN KMT2A	4.19e-05	210	104	6	16565220
Pubmed	Experimental and computational approaches yield a high-resolution, 1-Mb physical map of the region harboring the mouse t haplotype sterility factor, tcs1.	TULP4 SYNJ2	5.29e-05	4	104	2	11471064
Pubmed	The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells.	SPIRE1 NPHP4	5.29e-05	4	104	2	26644512
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2B KMT2A	5.29e-05	4	104	2	23129768
Pubmed	Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation.	KMT2B KMT2A	5.29e-05	4	104	2	17166833
Pubmed	Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA.	KMT2B KMT2A	5.29e-05	4	104	2	34156981
Pubmed	WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket.	KMT2B KMT2A	5.29e-05	4	104	2	18840606
Pubmed	APC/Cdh1 targets PECAM-1 for ubiquitination and degradation in endothelial cells.	CCNA2 FZR1	5.29e-05	4	104	2	31489637
Pubmed	Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.	KMT2B KMT2A	5.29e-05	4	104	2	26267306
Pubmed	MLL1 is required for PAX7 expression and satellite cell self-renewal in mice.	KMT2B KMT2A	5.29e-05	4	104	2	31534153
Pubmed	Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.	KMT2B KMT2A	5.29e-05	4	104	2	25834037
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SRRM1 SPIRE1 PAK6 SYNJ2 PI4KA SH3D19 KMT2A REEP4 FGD6 DMTN DYRK2	5.53e-05	861	104	11	36931259
Pubmed	Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.	KMT2B CCNA2 KMT2A	5.69e-05	25	104	3	25664857
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	KMT2B ANK2 DAG1 ID4 TULP4 SYNJ2 RPUSD2	6.16e-05	329	104	7	17474147
Pubmed	Functional proteomics mapping of a human signaling pathway.	KIF18A KMT2B ANK3 ZMYND8 DCTN1 LDB2 KANSL1 BAZ1A KDM2A	7.30e-05	591	104	9	15231748
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	SRRM1 NUP98 SSB RALY DUS2 SYNJ2 ELMOD3	8.59e-05	347	104	7	16033648
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	ANK2 ANK3	8.80e-05	5	104	2	25950943
Pubmed	Evolving Catalytic Properties of the MLL Family SET Domain.	KMT2B KMT2A	8.80e-05	5	104	2	26320581
Pubmed	Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.	KMT2B KMT2A	8.80e-05	5	104	2	25561738
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK2 ANK3	8.80e-05	5	104	2	25362471
Pubmed	MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.	KMT2B KMT2A	8.80e-05	5	104	2	28609655
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2B L3MBTL2 NUP98 TNRC18 ZZZ3 BAZ1A KMT2A	9.23e-05	351	104	7	38297188
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	KIF18A RRP1B KIF4A SSB KCTD1 MCM10 PHF8 RALY BAZ1A C8orf33	9.53e-05	759	104	10	35915203
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ANK2 L3MBTL2 ZMYND8 NUP98 KIF4A SRCAP DCTN1 BAZ1A SH3D19 KMT2A PRR14L	1.14e-04	934	104	11	33916271
Pubmed	Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.	KMT2B KMT2A	1.32e-04	6	104	2	24176642
Pubmed	APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.	CCNA2 FZR1	1.32e-04	6	104	2	27653696
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	ANK2 ANK3	1.32e-04	6	104	2	23728480
Pubmed	MLL associates specifically with a subset of transcriptionally active target genes.	KMT2B KMT2A	1.32e-04	6	104	2	16199523
Pubmed	Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation.	SETBP1 KMT2A	1.32e-04	6	104	2	35036869
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SRRM1 RRP1B NUP98 SSB INF2	1.35e-04	163	104	5	22113938
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	KMT2B SH3GL3 ZMYND8 PAK6 DCTN1 TYMS DUS2 ZZZ3 INF2 PI4KA CEP126 C8orf33	1.38e-04	1124	104	12	21900206
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MRPS31 SRRM1 ANK2 ANK3 L3MBTL2 RRP1B MRPL45 DCTN1 RALY NBAS INF2 PI4KA CDK5RAP1 REEP4	1.40e-04	1487	104	14	33957083
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	SRRM1 KIF18A KIF4A MCM10 SRCAP CCNA2 PI4KA KMT2A KDM2A	1.41e-04	645	104	9	25281560
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	SRRM1 RRP1B NUP98 KIF4A RALY INF2 BAZ1A PI4KA KDM2A	1.67e-04	660	104	9	32780723
Pubmed	Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition.	NUP98 FZR1	1.84e-04	7	104	2	16479161
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK2 ANK3	1.84e-04	7	104	2	7495297
Pubmed	Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C.	CCNA2 FZR1	1.84e-04	7	104	2	31455778
Pubmed	GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells.	GATA6 MUC5AC	1.84e-04	7	104	2	22554936
Pubmed	Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.	RRP1B OBSCN KDM2A	2.03e-04	38	104	3	23537643
Pubmed	Large-scale identification of mammalian proteins localized to nuclear sub-compartments.	SRRM1 BAZ1A KMT2A	2.03e-04	38	104	3	11555636
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SRRM1 KMT2B RRP1B ZMYND8 NUP98 SSB DCTN1 RALY BAZ1A KMT2A	2.31e-04	847	104	10	35850772
Pubmed	Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.	SRRM1 ZMYND8 INF2	2.37e-04	40	104	3	28805822
Pubmed	Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis.	GATA6 TET3	2.45e-04	8	104	2	26199412
Pubmed	Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.	ANK3 OBSCN	2.45e-04	8	104	2	28826662
Pubmed	CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication.	PHF8 CCNA2	2.45e-04	8	104	2	33010150
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2B KMT2A	2.45e-04	8	104	2	23130995
Pubmed	A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice.	CCNA2 TYMS	2.45e-04	8	104	2	24662053
Pubmed	CRL3-SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling.	ZMYND8 INF2	2.45e-04	8	104	2	31776466
Interaction	NUP43 interactions	SRRM1 KMT2B DSCAM L3MBTL2 RRP1B ZMYND8 NUP98 PHF8 SRCAP ZZZ3 KANSL1 BAZ1A PI4KA KMT2A KDM2A PDZD2	7.27e-08	625	100	16	int:NUP43
Interaction	H3C1 interactions	KMT2B ANK2 ANK3 L3MBTL2 RRP1B ZMYND8 KIF4A SSB PHF8 SRCAP RALY TYMS TNRC18 BAZ1A HASPIN KMT2A KDM2A PRR14L PDZD2	8.11e-08	901	100	19	int:H3C1
Interaction	RERE interactions	KMT2B L3MBTL2 TLX3 ZMYND8 ZZZ3 KANSL1 KMT2A	4.00e-07	93	100	7	int:RERE
Interaction	KANSL1 interactions	KMT2B L3MBTL2 DUS2 FZR1 ZZZ3 KANSL1 KMT2A	4.97e-07	96	100	7	int:KANSL1
Interaction	ASH2L interactions	SRRM1 KMT2B PHF8 SRCAP ZZZ3 KANSL1 SETBP1 KMT2A KDM2A DYRK2	7.99e-07	265	100	10	int:ASH2L
Interaction	ELF1 interactions	KMT2B L3MBTL2 SRCAP ZZZ3 KANSL1 KMT2A KDM2A	3.12e-06	126	100	7	int:ELF1
Interaction	ANAPC4 interactions	KIF18A NUP98 KIF4A PHF8 USP37 CCNA2 FZR1	3.12e-06	126	100	7	int:ANAPC4
Interaction	CXXC1 interactions	KMT2B NUP98 ZZZ3 KANSL1 KMT2A TET3 DYRK2	4.25e-06	132	100	7	int:CXXC1
Interaction	GPRASP1 interactions	DSCAM HTR7 CHRM2 FZR1 C8orf33	2.06e-05	67	100	5	int:GPRASP1
Interaction	KANSL2 interactions	KMT2B L3MBTL2 ZZZ3 KANSL1 KMT2A	2.55e-05	70	100	5	int:KANSL2
Interaction	CDC27 interactions	KIF18A NUP98 PHF8 USP37 DCTN1 CCNA2 FZR1 KMT2A	3.39e-05	249	100	8	int:CDC27
Interaction	H3C3 interactions	SRRM1 KMT2B L3MBTL2 RRP1B PIGK KIF4A PHF8 SRCAP BAZ1A KMT2A KDM2A	3.47e-05	495	100	11	int:H3C3
Interaction	PHF20L1 interactions	KMT2B ZMYND8 ZZZ3 KANSL1 KMT2A	3.57e-05	75	100	5	int:PHF20L1
Interaction	SETD1B interactions	KMT2B ZZZ3 KANSL1 KMT2A DYRK2	3.57e-05	75	100	5	int:SETD1B
Interaction	ACTC1 interactions	SRRM1 KMT2B PEX1 KIF4A SPIRE1 SSB SRCAP NPHP4 DCTN1 FZR1 ZZZ3 INF2 DMTN	3.87e-05	694	100	13	int:ACTC1
Interaction	H2BC21 interactions	KMT2B ZMYND8 OBSCN KIF4A SSB PHF8 SRCAP ZZZ3 BAZ1A KMT2A KDM2A C8orf33 DYRK2	3.99e-05	696	100	13	int:H2BC21
Interaction	KLF12 interactions	MRPS31 KMT2B L3MBTL2 RRP1B SSB ZZZ3 KMT2A	5.17e-05	194	100	7	int:KLF12
Interaction	KANSL3 interactions	KMT2B L3MBTL2 ZZZ3 KANSL1 KMT2A	6.89e-05	86	100	5	int:KANSL3
Interaction	GKAP1 interactions	KIF18A L3MBTL2 NPHP4 DCTN1	7.94e-05	46	100	4	int:GKAP1
Interaction	ZNF608 interactions	KMT2B TLX3 ZZZ3 KANSL1 KMT2A	1.00e-04	93	100	5	int:ZNF608
Interaction	DUS2 interactions	SSB DUS2 KANSL1	1.08e-04	19	100	3	int:DUS2
Interaction	ELF2 interactions	KMT2B L3MBTL2 PHF8 SRCAP KANSL1 KMT2A	1.28e-04	156	100	6	int:ELF2
Interaction	H2BC8 interactions	KIF18A KMT2B ZMYND8 KIF4A MCM10 SRCAP CCNA2 BAZ1A RPUSD2 KMT2A KDM2A	1.34e-04	576	100	11	int:H2BC8
Interaction	PHF20 interactions	KMT2B ZZZ3 KANSL1 KMT2A	1.39e-04	53	100	4	int:PHF20
Interaction	MEN1 interactions	SRRM1 KMT2B RRP1B ZMYND8 NUP98 SSB PHF8 SRCAP DCTN1 RALY KANSL1 BAZ1A SETBP1 KMT2A KDM2A	1.63e-04	1029	100	15	int:MEN1
Interaction	CDC20 interactions	KIF18A NUP98 PHF8 USP37 CCNA2 FZR1 KMT2A	1.67e-04	234	100	7	int:CDC20
Interaction	FZR1 interactions	MRPS31 SRRM1 ANK2 RRP1B TROAP NUP98 ID4 SSB PHF8 USP37 DCTN1 CCNA2 RALY FZR1 KANSL1 MRPL14	2.04e-04	1172	100	16	int:FZR1
Interaction	P4HA3 interactions	SRRM1 KMT2B ZMYND8 SRCAP HASPIN	2.50e-04	113	100	5	int:P4HA3
Interaction	TFAM interactions	MRPS31 CLUAP1 RRP1B TLX3 ZMYND8 SSB MRPL45 FZR1 C8orf33	2.61e-04	424	100	9	int:TFAM
Interaction	MAD2L1 interactions	L3MBTL2 NUP98 PHF8 SRCAP CCNA2 ZZZ3 KDM2A	2.62e-04	252	100	7	int:MAD2L1
Interaction	ELF4 interactions	KMT2B L3MBTL2 SRCAP ZZZ3 KANSL1	2.71e-04	115	100	5	int:ELF4
GeneFamily	Zinc fingers CXXC-type	KMT2B KMT2A KDM2A TET3	5.69e-08	12	61	4	136
GeneFamily	PHD finger proteins	KMT2B ZMYND8 PHF8 BAZ1A KMT2A KDM2A	5.73e-07	90	61	6	88
GeneFamily	Fibronectin type III domain containing	DSCAM ABI3BP OBSCN PTPRT	2.08e-03	160	61	4	555
GeneFamily	Mitochondrial ribosomal proteins	MRPS31 MRPL45 MRPL14	2.41e-03	79	61	3	646
GeneFamily	PHD finger proteins\|Lysine demethylases	PHF8 KDM2A	2.95e-03	24	61	2	485
Coexpression	GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_DN	CLUAP1 DUS2 CEP126 DYRK2	2.16e-06	24	102	4	M19520
Coexpression	MEBARKI_HCC_PROGENITOR_FZD8CRD_UP	KIF18A CENPL TROAP SH3GL3 KIF4A CCDC80 MCM10 PAK6 CCNA2 TYMS HASPIN PLD5	3.13e-06	588	102	12	M38992
Coexpression	HOWARD_NK_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_3DY_UP	KIF18A TROAP MCM10 CCNA2 TYMS	6.94e-06	68	102	5	M41108
Coexpression	VAN_DEN_BIGGELAAR_PBMC_PREVNAR_9MO_INFANT_STIMULATED_VS_UNSTIMULATED_9MO_UP	KIF18A USP17L2 KIF4A MCM10 CCNA2 TYMS	1.06e-05	127	102	6	M40952
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_2_CELL	KIF18A CENPL TROAP KIF4A MCM10 LDB2 CCNA2 FZR1	2.32e-05	300	102	8	M45675
Coexpression	BROWNE_HCMV_INFECTION_24HR_UP	KMT2B HTR7 SH3GL3 NUP98 PHF8 BAZ1A	2.34e-05	146	102	6	M12275
Coexpression	FISCHER_DREAM_TARGETS	SRRM1 KIF18A L3MBTL2 CENPL TROAP PIGK NUP98 KIF4A MCM10 USP37 CCNA2 FZR1 HASPIN REEP4	2.34e-05	969	102	14	M149
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN MUC5AC	2.80e-05	402	102	9	MM454
Coexpression	HEVNER_CORTEX_RADIAL_GLIA_PROGENITORS	CENPL DAG1 ID4 KIF4A CCDC80 MCM10 CCNA2 TYMS HASPIN	4.89e-05	432	102	9	MM419
Coexpression	VILLANUEVA_LIVER_CANCER_KRT19_UP	KIF18A RRP1B TROAP KIF4A MCM10 USP37	6.44e-05	175	102	6	M336
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	KIF18A CENPL TROAP KIF4A MCM10 USP37 CCNA2 TYMS FZR1 INF2 PI4KA REEP4 KCTD18	7.24e-05	939	102	13	M45768
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KMT2B USP37 KANSL1 TULP4 KDM2A PRR14L	7.53e-05	180	102	6	M8239
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	KIF18A L3MBTL2 RRP1B CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	8.70e-05	578	102	10	M2368
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	ANK2 ANK3 DSCAM ZMYND8 ADGRB1 PEX1 PTPRT SEMA6D TULP4 SBF2 CEP126 BSN DMTN DYRK2	9.74e-05	1106	102	14	M39071
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	KIF18A L3MBTL2 RRP1B CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	1.13e-04	597	102	10	MM1309
Coexpression	HAY_BONE_MARROW_ERYTHROBLAST	MRPS31 KIF18A TPRA1 CENPL TROAP ZMYND8 KIF4A SSB MRPL45 MCM10 CCNA2 NBAS MRPL14 BAZ1A DMTN	1.17e-04	1271	102	15	M39197
Coexpression	CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5	ANK3 GATA6 DAG1 SPIRE1 CCDC80 SYNJ2 SH3D19 DYRK2 PDZD2	1.30e-04	491	102	9	M13661
Coexpression	GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP	KIF18A CLUAP1 GATA6 KIF4A STK35 CCNA2	1.34e-04	200	102	6	M6065
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA	ANK2 ANK3 DSCAM SH3GL3 PAK6 LDB2 SEMA6D CEP126 DMTN	1.62e-04	506	102	9	M39067
Coexpression	NUYTTEN_EZH2_TARGETS_DN	RRP1B CENPL TROAP NUP98 KIF4A MCM10 PAK6 USP37 CCNA2 TYMS HASPIN REEP4 MUC5AC	1.70e-04	1023	102	13	M17122
Coexpression	SABATES_COLORECTAL_ADENOMA_DN	ANK2 ABI3BP CCDC80 TMEM200A LYVE1 SEMA6D SETBP1	1.72e-04	299	102	7	M14791
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A MCM10 LDB2 CCNA2 TYMS LYVE1	7.57e-10	194	103	9	3a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A LDB2 CCNA2 TYMS LYVE1 HASPIN	7.92e-10	195	103	9	5790b47b0e028e49b99bda8d6d9e80ac79208cdf
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF18A CENPL TROAP SH3GL3 KIF4A NPHP4 CCNA2 TYMS	8.10e-09	176	103	8	b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCell	COVID-cycling-\|COVID / Condition, Cell_class and T cell subcluster	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	1.20e-08	185	103	8	eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCell	COVID-cycling\|COVID / Condition, Cell_class and T cell subcluster	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	1.20e-08	185	103	8	5112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF18A CENPL TROAP KIF4A CCNA2 TYMS FZR1 REEP4	1.47e-08	190	103	8	cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCell	Proliferating\|World / shred by cell class for mouse tongue	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS FZR1 HASPIN	1.60e-08	192	103	8	f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A CCNA2 TYMS LYVE1 HASPIN	1.88e-08	196	103	8	20383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A CCNA2 TYMS LYVE1 HASPIN	1.88e-08	196	103	8	0644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	1.95e-08	197	103	8	7eb4c1cffd0366204af7e63adc8f751685601a94
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF18A TROAP KIF4A MCM10 CCNA2 RALY TYMS SEMA6D	2.03e-08	198	103	8	1fa213e79d828bff6465bde116536dd1b80d94e0
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A MCM10 USP37 LDB2 CCNA2 TYMS LYVE1	1.66e-07	174	103	7	66555c610251ea04f968c258e312d720c18e7cde
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A CCNA2 LYVE1 HASPIN	1.80e-07	176	103	7	8385435074cc5235b7af7424974f609388fc2cff
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF18A CENPL TROAP KIF4A CCNA2 NEK5 ARHGAP29	1.94e-07	178	103	7	ea10117026021c959ffc871fc377cdb3e161d264
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF18A CENPL TROAP KIF4A CCNA2 TYMS HASPIN	2.09e-07	180	103	7	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	P15-Endothelial-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPL TROAP NPHP4 CCNA2 TYMS FZR1 REEP4	2.17e-07	181	103	7	0c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCell	P15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPL TROAP NPHP4 CCNA2 TYMS FZR1 REEP4	2.17e-07	181	103	7	f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	2.34e-07	183	103	7	df8568751205313d149939ea2683097e3652a60b
ToppCell	URO-Lymphocyte-T_NK-T_NK_proliferative\|URO / Disease, Lineage and Cell Type	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	2.52e-07	185	103	7	0ae9c646679c69a553eda670aef0e0495feb0286
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 HASPIN	2.61e-07	186	103	7	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 HASPIN	2.61e-07	186	103	7	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	NS-critical-d_0-4-Lymphoid-NKT-proliferating\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	2.91e-07	189	103	7	d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCell	facs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 HASPIN	2.91e-07	189	103	7	bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCell	facs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 HASPIN	2.91e-07	189	103	7	96f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF18A CENPL TROAP KIF4A CCNA2 TYMS FZR1	2.91e-07	189	103	7	d049f33115610bda4489968759f754730698b9cd
ToppCell	Int-URO-Lymphocyte-T_NK-T_NK_proliferative\|Int-URO / Disease, Lineage and Cell Type	KIF18A TROAP CYP27B1 KIF4A MCM10 CCNA2 TYMS	3.02e-07	190	103	7	005967c540418b85311308072a07c684f4296aef
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL TROAP KIF4A CCNA2 TYMS GZMM HASPIN	3.02e-07	190	103	7	b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KIF18A CENPL TROAP KIF4A CCNA2 FZR1 REEP4	3.13e-07	191	103	7	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF18A CENPL TROAP KIF4A CCNA2 TYMS FZR1	3.13e-07	191	103	7	f764cc21fef87ebad765011098f647ae1bdf6158
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KIF18A CENPL TROAP KIF4A CCNA2 FZR1 REEP4	3.24e-07	192	103	7	27723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KIF18A CENPL TROAP KIF4A CCNA2 FZR1 REEP4	3.24e-07	192	103	7	026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF18A CENPL TROAP KIF4A CCNA2 TYMS HASPIN	3.24e-07	192	103	7	90d25b0b38f1cd7a98c76c1f9e38166da6d7a316
ToppCell	LAM-Endothelial-LymEndo\|LAM / Condition, Lineage and Cell class	ADGRG3 ABI3BP CCDC80 LDB2 LYVE1 ARHGAP29 DMTN	3.35e-07	193	103	7	68eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Control / Condition, Lineage and Cell class	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.35e-07	193	103	7	33d409d6ed1c606337248587ad997ac5f67f081d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	3.47e-07	194	103	7	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF18A CENPL TROAP KIF4A CCNA2 FZR1 PDZD2	3.47e-07	194	103	7	d840c1949c328779426c9172e02da09e968f0567
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF18A CENPL TROAP KIF4A CCNA2 TYMS REEP4	3.60e-07	195	103	7	bda3ca3d26afd06c226bc6fd1d8fd85a0e4fb52b
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF18A CENPL TROAP KIF4A CCNA2 FZR1 REEP4	3.60e-07	195	103	7	742c82c86487314cdb3178012004adb1164bcbdb
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRPS31 CLUAP1 PTPRT CFAP54 NEK5 CEP126 MUC5AC	3.60e-07	195	103	7	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A CCNA2 LYVE1 HASPIN	3.60e-07	195	103	7	a838bddeed487154791b69d27a68673783ff63c0
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.72e-07	196	103	7	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	KIF18A TROAP KIF4A CCDC80 MCM10 CCNA2 TYMS	3.72e-07	196	103	7	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	Control-T/NK_proliferative\|Control / Disease condition and Cell class	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.72e-07	196	103	7	7b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF18A CENPL TROAP KIF4A CCNA2 TYMS FZR1	3.72e-07	196	103	7	62b2de1d38a99ab23211bf51595845f8a1fdb7d2
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CENPL TROAP KIF4A CCNA2 TYMS HASPIN	3.72e-07	196	103	7	5ddd314d3def3776dc7da83778d41c6436ca51ac
ToppCell	(3)_MNP-(3)_Macrophage_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	048bc4f8fd5d4f394e2384700640f72042336597
ToppCell	Mild_COVID-19-T/NK-proliferating_T/NK\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	5fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	3.85e-07	197	103	7	84ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCell	Healthy/Control-T/NK_proliferative\|World / Disease group and Cell class	CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	4a4d3083938783d6f5b87da02f10e501917da0b4
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	d7a9296092153cf66426911fecd810f0c1ef978e
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	dcff23240bb7cb652d7426b29355aa74442ef6fc
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A CCNA2 TYMS LYVE1	3.85e-07	197	103	7	a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	434a5686a103bb766e0d80038413f0e12ea3981a
ToppCell	Mild-Lymphoid-T-Proliferating_T\|Mild / Condition, Lineage, Cell class and cell subclass	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	794517c70089da109f4c6489fe406c0ba6882b76
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	6bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	c0a71a9452febda433bc544e4ac0a79c43dcf13e
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	f34b1e34f1f0694564031077172c890b233ce8b7
ToppCell	distal-Hematologic-Proliferating_NK/T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.85e-07	197	103	7	04b10879e48c101d1de449db0bc6b6484090b965
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A CENPL TROAP KIF4A CCNA2 TYMS FZR1	3.85e-07	197	103	7	9b2c67de46bd59bf56c81a0d10b84cf4a041c120
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A CENPL TROAP KIF4A CCNA2 LYVE1 HASPIN	3.85e-07	197	103	7	1c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK-Cycling_NK\|lymph-node_spleen / Manually curated celltypes from each tissue	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.99e-07	198	103	7	b2868a897dd96494cf1829c30e0ce508f52efdf3
ToppCell	distal-2-Hematologic-Proliferating_NK/T\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.99e-07	198	103	7	a5fd710df5669c95fc5b5ef6e5cfafe6687c7b72
ToppCell	medial-2-Hematologic-Proliferating_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	3.99e-07	198	103	7	64a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCell	medial-Hematologic-Proliferating_Macrophage-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	3.99e-07	198	103	7	fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.99e-07	198	103	7	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	distal-Hematologic-Proliferating_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	3.99e-07	198	103	7	8afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCell	distal-Hematologic-Proliferating_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	3.99e-07	198	103	7	2b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF18A TROAP KIF4A MCM10 PTPRT CCNA2 TYMS	3.99e-07	198	103	7	f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell	proximal-Hematologic-Proliferating_NK/T\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL TROAP KIF4A CCNA2 TYMS GZMM HASPIN	3.99e-07	198	103	7	6c894fda309ec3d4bb446f63d5dde4e7f8c4fd89
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	3.99e-07	198	103	7	dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell	proximal-3-Hematologic-Proliferating_NK/T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL TROAP KIF4A CCNA2 TYMS GZMM HASPIN	3.99e-07	198	103	7	2777c5efe84ce3dbbe6175ecc1c987bc816ab74b
ToppCell	proximal-Hematologic-Proliferating_NK/T-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPL TROAP KIF4A CCNA2 TYMS GZMM HASPIN	3.99e-07	198	103	7	2e121899f58a5024e26441bd326aac12c37fe6d1
ToppCell	medial-Hematologic-Proliferating_Macrophage\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	3.99e-07	198	103	7	da6963184c32761c896a9b91a5321ad84b583736
ToppCell	mLN-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	ADGRG3 TROAP KIF4A MCM10 LDB2 CCNA2 TYMS	4.12e-07	199	103	7	c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCell	3'_v3-bone_marrow-Lymphocytic_NK-Cycling_NK\|bone_marrow / Manually curated celltypes from each tissue	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.12e-07	199	103	7	6321140a1ebc1ff793fb6221a31e884368e42fa5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	KIF18A CENPL TROAP KIF4A CCNA2 TYMS REEP4	4.12e-07	199	103	7	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	Biopsy_Other_PF-Endothelial-Lymphatic_Endothelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ADGRG3 ABI3BP CCDC80 LDB2 LYVE1 ARHGAP29 DMTN	4.12e-07	199	103	7	aa80c77fe4f6a141c780c7d8ecfff5d5a1c3b845
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.12e-07	199	103	7	88d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCell	distal-Hematologic-Proliferating_NK/T\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.12e-07	199	103	7	4f02e03c118744fba0dfc5e3ed6dea4041f3d089
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS REEP4	4.12e-07	199	103	7	d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	4.12e-07	199	103	7	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	4.12e-07	199	103	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	distal-Hematologic-Proliferating_Macrophage\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	4.26e-07	200	103	7	3835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	4.26e-07	200	103	7	14c9ced92763858f3d35186cd3908bd0f4cfd872
ToppCell	distal-2-Hematologic-Proliferating_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	4.26e-07	200	103	7	0cd3b01fb7f579e5abf000adb8ec8adc7cd779c4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	medial-Hematologic-Proliferating_NK/T-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	ab1f9f99cb4a381a642a2cfb32e7f8d276c2dda4
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	4.26e-07	200	103	7	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	mLN-T_cell-cycling_gd_T\|mLN / Region, Cell class and subclass	ADGRG3 TROAP KIF4A MCM10 LDB2 CCNA2 TYMS	4.26e-07	200	103	7	4efeef51f885ee8f6dd3911a536cc49e3c14da98
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	e4eb915c29909cf8535a3603c68976545c05e54b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	mLN-(1)_T_cell-(18)_cycling_gd_T\|mLN / shred on region, Cell_type, and subtype	ADGRG3 TROAP KIF4A MCM10 LDB2 CCNA2 TYMS	4.26e-07	200	103	7	e8a0a88a8344e80783931115bbe6cd5b62a4c1f7
ToppCell	NS-critical-LOC-Lymphoid-Treg\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	d51e5c8c154b073caaf0cc09a3a3c0aafd57e44b
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-T/NK_proliferative\|Int-URO / Disease, condition lineage and cell class	KIF18A TROAP CYP27B1 KIF4A MCM10 CCNA2 TYMS	4.26e-07	200	103	7	99acc1ea01288efdd5b166aa20d66735f2bbe543
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte-\|healthy_donor / Disease condition, Lineage, Cell class and subclass	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	cea58274efbe7f9e3c3ef9fbb768ebfb917e21d9
ToppCell	medial-Hematologic-Proliferating_NK/T\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	bfde42e00a9a6b858937de87cd19c9ed3677d954
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-17\|World / Primary Cells by Cluster	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 TYMS	4.26e-07	200	103	7	4417f14d45ce683c1a45ec989ae63ee6c047353e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	KIF18A CENPL TROAP KIF4A MCM10 CCNA2 HASPIN	4.26e-07	200	103	7	0bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell	COVID-19-Lymphoid-Proliferating_CD8_T_cells\|COVID-19 / Condition, Lineage and Cell class	KIF18A TROAP KIF4A MCM10 CCNA2 TYMS HASPIN	4.26e-07	200	103	7	b239c711cce967826432fdbd5f88eba98a88bb0c
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A	KIF18A TROAP ZMYND8 NUP98 MCM10 CCNA2 DIP2C DYRK2	1.47e-06	181	101	8	1791_DN
Disease	Down syndrome (implicated_via_orthology)	DSCAM SYNJ2 DYRK2	1.72e-05	15	101	3	DOID:14250 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	ANK2 DSCAM SRCAP SETBP1 KMT2A	1.74e-05	93	101	5	C1535926
Disease	lymphatic vessel endothelial hyaluronic acid receptor 1 measurement	STK35 LYVE1	3.20e-04	8	101	2	EFO_0020539
Disease	Acute erythroleukemia - M6a subtype	NUP98 KMT2A	3.20e-04	8	101	2	C2930975
Disease	Acute myeloid leukemia FAB-M6	NUP98 KMT2A	3.20e-04	8	101	2	C2930976
Disease	Acute erythroleukemia - M6b subtype	NUP98 KMT2A	3.20e-04	8	101	2	C2930977
Disease	Acute erythroleukemia	NUP98 KMT2A	3.20e-04	8	101	2	C2930974
Disease	Liver carcinoma	KIF18A KMT2B TROAP KIF4A MCM10 TYMS LYVE1 KMT2A	3.59e-04	507	101	8	C2239176
Disease	chronic kidney disease, Proteinuria	SH3GL3 KMT2A	6.25e-04	11	101	2	EFO_0003884, HP_0000093
Disease	brain aneurysm	DSCAM CCDC80 FGD6 PDZD2	6.26e-04	113	101	4	EFO_0003870
Disease	Colorectal Carcinoma	ANK2 OBSCN PAK6 PTPRT TYMS ZZZ3 SETBP1 DIP2C KDM2A	6.92e-04	702	101	9	C0009402
Disease	acute myeloid leukemia (implicated_via_orthology)	NUP98 KMT2A	7.49e-04	12	101	2	DOID:9119 (implicated_via_orthology)
Disease	Small cell carcinoma of lung	PAK6 DIP2C KMT2A	8.51e-04	54	101	3	C0149925
Disease	kynurenic acid measurement	SEMA6D DYRK2	8.83e-04	13	101	2	EFO_0010506
Disease	triacylglycerol 48:4 measurement	DSCAM PLD5	1.03e-03	14	101	2	EFO_0010407
Disease	third ventricle volume measurement	ANK3 LDB2	1.18e-03	15	101	2	EFO_0010335
Disease	macrophage inflammatory protein 1b measurement	ZNF438 ANK3 DAG1 MRPL45	1.25e-03	136	101	4	EFO_0008219
Disease	skin pigmentation measurement	ID4 RALY SEMA6D PLD5	1.28e-03	137	101	4	EFO_0007009
Disease	forced expiratory volume	CLUAP1 DSCAM SH3GL3 ID4 RALY KANSL1 TULP4 KDM2A FGD6	1.56e-03	789	101	9	EFO_0004314
Disease	Myeloid Leukemia	SETBP1 KMT2A	1.71e-03	18	101	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SETBP1 KMT2A	1.71e-03	18	101	2	C0023466
Disease	congenital heart disease (implicated_via_orthology)	USP17L2 KMT2B KMT2A	1.73e-03	69	101	3	DOID:1682 (implicated_via_orthology)
Disease	migraine disorder, endometriosis	ZNF438 SBF2 FGD6	2.03e-03	73	101	3	EFO_0001065, MONDO_0005277
Disease	unipolar depression, bipolar disorder	ANK3 L3MBTL2 ZMYND8 SETBP1	2.06e-03	156	101	4	EFO_0003761, MONDO_0004985
Disease	systemising measurement	DSCAM NBAS	2.33e-03	21	101	2	EFO_0010221
Disease	epilepsy (implicated_via_orthology)	ANK2 KIF4A SBF2 BSN	2.42e-03	163	101	4	DOID:1826 (implicated_via_orthology)
Disease	Mood Disorders	ANK3 HTR7 DCTN1 CHRM2	2.70e-03	168	101	4	C0525045
Disease	sensory peripheral neuropathy, remission	PTPRT KMT2A	2.80e-03	23	101	2	EFO_0009785, MONDO_0002321
Disease	frailty measurement	ANK3 REEP4	2.80e-03	23	101	2	EFO_0009885
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	ZNF438 TPRA1 KMT2B TET3	2.81e-03	170	101	4	EFO_0000685, EFO_0007791, EFO_0007837
Disease	Leukemia, Myelocytic, Acute	NUP98 PTPRT SETBP1 KMT2A	3.00e-03	173	101	4	C0023467
Disease	congenital heart disease (is_implicated_in)	GATA6 NPHP4	3.05e-03	24	101	2	DOID:1682 (is_implicated_in)
Disease	squamous cell lung carcinoma, family history of lung cancer	TLX3 NBAS PLD5	3.14e-03	85	101	3	EFO_0000708, EFO_0006953

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLTLKPPLRRSSSVK	CFAP54	2676	Q96N23
LSPFKKRIQPTIRRT	ELMOD3	116	Q96FG2
PKKAPTARKTTTRRP	DCTN1	136	Q14203
TARKTTTRRPKPTRP	DCTN1	141	Q14203
AIRTLRSKRTPLPRK	C8orf33	141	Q9H7E9
KVISVTVKPPPRSLR	ADGRB1	851	O14514
VKPSRTIRPLALPSK	GZMM	121	P51124
KPPDRVRLPKSLFRS	ADGRG3	126	Q86Y34
KPPPSREKKVTRTIL	CHRM2	376	P08172
PKRGRPQVRLPVKTR	BAZ1A	1261	Q9NRL2
PPTRESRVKVLRKLA	CCDC80	321	Q76M96
KRPRVTVPLVRRVKT	RALY	146	Q9UKM9
IIIPPRKCTAPTRVT	ANK2	991	Q01484
LRLQFPPRIRKTPKL	CFAP99	271	D6REC4
PVRPKTRTVLVPERS	CYP27B1	486	O15528
PKTRRVSSLRLEPPK	FAM47C	791	Q5HY64
KLTPRPATRVRPKAL	NUP98	551	P52948
TLRRPKPVVDPSRIT	PAK6	46	Q9NQU5
PAPASTSIPRRKKLI	LYVE1	186	Q9Y5Y7
KTKIRRSPSKPLPEV	SSB	86	P05455
ESRRLPPIQKPKILR	SBF2	861	Q86WG5
KRIPPTKTRPLRQGS	L3MBTL2	631	Q969R5
IPTEKRTRRKLMPSP	KIF18A	661	Q8NI77
PAEPTRQPTTKRRKR	LDB2	246	O43679
PKLPKKVQTVRSRPL	LMOD2	401	Q6P5Q4
PNSLVRKVKRTLPSP	BSN	2886	Q9UPA5
KKPRTPRPVPRVTTK	DAG1	451	Q14118
RTPRVPSVIRIKQEP	KCTD1	241	Q719H9
PRVTKCKARSPVRLP	PDZD2	1271	O15018
PPRSRISVPIKRNAI	NEK5	311	Q6P3R8
PGKVRKRTTIRSQPL	FAM218A	121	Q96MZ4
VLTRRLPPIKEAKPR	PI4KA	776	P42356
KRRLVRPNSIVPLSK	KANSL1	601	Q7Z3B3
STPVPLPEKRRSILR	KMT2B	591	Q9UMN6
PALPRTKRVARTPKA	MCM10	181	Q7L590
RDITRPPKTVATTRP	MUC5AC	2051	P98088
ISLRPRTCPRVEKPT	MUC5AC	4881	P98088
RRLVPTIPPNKKVSK	ID4	76	P47928
RFAPPRKRPRTITKN	NBAS	501	A2RRP1
TGRIPPSTPRSKRLL	PIGK	136	Q92643
LLSVKGRPRPSPLVK	INF2	341	Q27J81
KTTVKPTKRPPSRIV	NPHP4	76	O75161
TPPSKRSLLKVVRRL	PTPRT	1346	O14522
LSVRVPRPKFKTRLQ	OBSCN	4061	Q5VST9
PTPQRVIKLKRTPLC	KCTD18	371	Q6PI47
PRTKIRPVSLPVDRL	ARHGAP29	1011	Q52LW3
LRSPRKPTRKISKIP	FZR1	161	Q9UM11
PLIKPQKRVPSSRRL	GATA6	426	Q92908
TRPKVRVPTIPITKP	KDM2A	526	Q9Y2K7
KQSSFILTPPRRKIP	CENPL	36	Q8N0S6
EKRISTPRPKIVSPV	ERVK-7	206	P61567
SQRRKAVSRKPVPPL	CEP126	126	Q9P2H0
PTPRQKKPRRSRTIF	BARX2	126	Q9UMQ3
LVNTLKRPKRPPLRE	DIP2C	261	Q9Y2E4
RIIIPPRKCTAPTRI	ANK3	1006	Q12955
RVPKDRPSLTVTPKR	HASPIN	86	Q8TF76
PPPKLRRRTFSLTEV	KIF4A	791	O95239
SPRRIKPVRIIPSSK	KMT2A	351	Q03164
KGTRRPVTCKIRILP	DUS2	146	Q9NX74
RPKTRRVAPLKDLPV	CCNA2	66	P20248
LPIRRKTRSLPDRTP	DMTN	261	Q08495
TPVPLISPKRQIRSR	ZMYND8	541	Q9ULU4
RRRLPKPPTGEKTSV	DYRK2	536	Q92630
RITPVEVTPKIPRSL	PEX1	431	O43933
EVTPKIPRSLKLQPR	PEX1	436	O43933
KRRLNKRFSRPSPIP	CCDC179	46	H3BU77
RPKKVSQIRIRKTIP	PRR14L	2006	Q5THK1
RSQSLRVVKRKPPVR	REEP4	221	Q9H6H4
PQKSRTLKRPTVLEP	DSCAM	1931	O60469
TRERVVPPPKKRRTG	RPUSD2	106	Q8IZ73
STVNVRTTKPPKRRP	MRPS31	111	Q92665
RTTKPPKRRPLKSLE	MRPS31	116	Q92665
SPLVAKKPLTTTPRR	RRP1B	736	Q14684
KKPLTTTPRRRPRAM	RRP1B	741	Q14684
PRREYKPRPVKRSSS	SH3GL3	251	Q99963
RLKSRPKEPSPSLTR	PLD5	21	Q8N7P1
RAVQPAPTRKPTVIR	SH3D19	246	Q5HYK7
GTRIKTPIPTSLRKR	MRPL14	116	Q6P1L8
SPATQEKKPIRRRPR	TMEM200A	31	Q86VY9
PAIKKPTLRRTGKPL	SYNJ2	1236	O15056
AIVPVRTKKRFTPPI	MRPL45	31	Q9BRJ2
VTISTSPPKRKRGRP	SRCAP	2996	Q6ZRS2
KPSVPLIKASRRRPA	SUPT20HL2	536	P0C7V6
TRRVLLRPEKRPPVS	HTR7	436	P34969
LSPTKPNRRVRKSEP	CLUAP1	391	Q96AJ1
QLKALKTRRPRSRVP	CDK5RAP1	161	Q96SZ6
KPIRLSPSKITEPLR	TNRC18	1131	O15417
PKISRASKSPKLPRI	TULP4	531	Q9NRJ4
LPKTPLKERISLPSR	TPRA1	211	Q86W33
KRRSPVPRAPSTKLR	STK35	151	Q8TDR2
RSRPPLNPVSARKLK	SPIRE1	346	Q08AE8
KRTSSPPRKTRRLSP	SRRM1	376	Q8IYB3
KFPTPKPRKTRTARL	FGD6	311	Q6ZV73
RRKTRPPVRLVPKVK	ZNF710	96	Q8N1W2
REPRPFPKLRILRKV	TYMS	271	P04818
KIPVRSQKRTPFPTV	TROAP	21	Q12815
PSVRKPIQIKKSRPR	TET3	601	O43151
PSSPEPKRRRLSKLR	NPIPB2	376	A6NJ64
RTPPKRKKPRTSFSR	TLX3	161	O43711
SPAELPSRTPRKKRR	TOR4A	81	Q9NXH8
RRKKPLPPRSIQDSL	USP37	511	Q86T82
ATLIIRPKFPRKLPR	PHF8	666	Q9UPP1
TTSIPSTPKRRPRPK	ABI3BP	456	Q7Z7G0
TLPRTGLKRTPSLKP	SEMA6D	1036	Q8NFY4
SLTVITPVKKKRGRP	SETBP1	576	Q9Y6X0
PPRNSKASRKKPILI	ZNF438	126	Q7Z4V0
PVSPVLKRIKRCLRS	ZZZ3	111	Q8IYH5
QLAPRKKLPLSSRRP	USP17L2	61	Q6R6M4
TRVPAKPILPTATVR	MXRA5	1606	Q9NR99