Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainRCC1

MYCBP2 HERC1

2.05e-0420202PF00415
DomainRCC1_3

MYCBP2 HERC1

2.26e-0421202PS50012
DomainRCC1_1

MYCBP2 HERC1

2.26e-0421202PS00625
DomainRCC1_2

MYCBP2 HERC1

2.26e-0421202PS00626
DomainReg_chr_condens

MYCBP2 HERC1

2.48e-0422202IPR000408
Domain-

MYCBP2 HERC1

2.48e-04222022.130.10.30
DomainRCC1/BLIP-II

MYCBP2 HERC1

2.72e-0423202IPR009091
DomainSPRY

RYR3 HERC1

3.86e-0387202SM00449
DomainSPRY

RYR3 HERC1

4.49e-0394202PF00622
DomainSPRY_dom

RYR3 HERC1

4.49e-0394202IPR003877
DomainB30.2/SPRY

RYR3 HERC1

4.58e-0395202IPR001870
DomainB302_SPRY

RYR3 HERC1

4.58e-0395202PS50188
DomainARM-type_fold

PSMD1 RYR3 EIF4G1

5.37e-03339203IPR016024
PathwayREACTOME_METABOLISM_OF_RNA

PNN THOC2 PSMD1 RBM25 EIF4G1

1.46e-04612135MM15547
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PNN THOC2 MYCBP2 BAZ1B PSMD1 RBM25 EIF4G1 DDX10

3.75e-0965322822586326
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

PNN THOC2 MYCBP2 BAZ1B PSMD1 RBM25 EIF4G1 DDX10 SLC12A2

5.66e-09102422924711643
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PNN THOC2 MYCBP2 BAZ1B PSMD1 RBM25 ZEB1 EIF4G1

1.41e-0877422815302935
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

PNN MYCBP2 RBM25 HERC1

2.35e-078522416051665
Pubmed

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.

PNN THOC2 RBM25 EIF4G1

7.65e-0711422431553912
Pubmed

Human transcription factor protein interaction networks.

PNN BAZ1B PSMD1 RBM25 ZEB1 EIF4G1 HERC1 DDX10

1.52e-06142922835140242
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

PNN THOC2 MYCBP2 BAZ1B EIF4G1 DDX10

5.86e-0675922635915203
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

PNN THOC2 BAZ1B PSMD1 ZEB1 EIF4G1 SLC12A2

6.29e-06120322729180619
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

THOC2 MYCBP2 RBM25 EIF4G1

7.44e-0620222424639526
Pubmed

Mapping the Genetic Landscape of Human Cells.

PNN PSMD1 RBM25 EIF4G1 CLSPN

7.87e-0645122530033366
Pubmed

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.

MYCBP2 PSMD1 HERC1

9.35e-066522328276505
Pubmed

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors.

MYCBP2 ZEB1

1.07e-05822225460509
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PNN THOC2 PSMD1 RBM25 EIF4G1

1.33e-0550322516964243
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

PNN THOC2 RBM25 PCMTD1

1.57e-0524422429884807
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

PNN THOC2 BAZ1B RBM25 DDX10

1.76e-0553322530554943
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PNN THOC2 BAZ1B PSMD1 RBM25 EIF4G1 DDX10

1.89e-05142522730948266
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

PNN THOC2 MYCBP2 BAZ1B RBM25

2.03e-0554922538280479
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PNN THOC2 BAZ1B RBM25 EIF4G1 DDX10

2.15e-0595422636373674
Pubmed

Physiological and pathophysiological characteristics of ataxin-3 isoforms.

PSMD1 WDR87 RBM25 EIF4G1

2.72e-0528122430455355
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

PNN BAZ1B RBM25 EIF4G1 DDX10

3.23e-0560522528977666
Pubmed

Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.

PSMD1 WDR87

3.46e-051422228878358
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

PNN THOC2 BAZ1B RBM25 EIF4G1

4.88e-0566022532780723
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

PNN BAZ1B RBM25 DDX10

5.21e-0533222425693804
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

PNN THOC2 BAZ1B RBM25

5.71e-0534022429478914
Pubmed

ROR2 Downregulation Activates the MSX2/NSUN2/p21 Regulatory Axis and Promotes Dental Pulp Stem Cell Senescence.

PSMD1 RBM25 EIF4G1

7.63e-0513122335356984
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

PSMD1 EIF4G1 HERC1

9.10e-0513922325476789
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

PNN THOC2 PSMD1 WDR87 RBM25 EIF4G1

9.56e-05124722627684187
Pubmed

TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.

PSMD1 DDX10

9.59e-052322229581427
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

PNN BAZ1B DDX10

1.10e-0414822332538781
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PNN MYCBP2 PSMD1 RBM25 EIF4G1 HERC1

1.12e-04128422617353931
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MYCBP2 PSMD1 N4BP2 ZEB1

1.27e-0441822434709266
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

THOC2 MYCBP2 PSMD1 RBM25 EIF4G1

1.27e-0480922532129710
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

PNN THOC2 BAZ1B RBM25 EIF4G1 DDX10

1.30e-04131822630463901
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PNN MYCBP2 BAZ1B PSMD1 EIF4G1 DDX10

1.50e-04135322629467282
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

PNN THOC2 BAZ1B RBM25 EIF4G1

1.58e-0484722535850772
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

THOC2 BAZ1B ZEB1

1.65e-0417022315582152
Pubmed

The sperm-associated antigen 6 interactome and its role in spermatogenesis.

MYCBP2 BAZ1B WDR87

2.62e-0419922331146259
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

BAZ1B PSMD1 RBM25 EIF4G1 CLSPN

2.98e-0497122533306668
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

THOC2 BAZ1B RBM25 DDX10 CLSPN

3.24e-0498922536424410
Pubmed

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

PNN THOC2 BAZ1B

3.29e-0421522330462309
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

EIF4G1 CLSPN

3.40e-044322234672947
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

PNN THOC2 BAZ1B RBM25 EIF4G1

3.63e-04101422532416067
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

PSMD1 RYR3 HERC1

4.06e-0423122336597993
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

PNN THOC2 HERC1

4.21e-0423422336243803
Pubmed

Functional proteomics mapping of a human signaling pathway.

MYCBP2 PSMD1 EIF4G1 HERC1

4.73e-0459122415231748
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PNN THOC2 MYCBP2 RBM25 EIF4G1

4.89e-04108222538697112
Pubmed

CUL4B Promotes Breast Carcinogenesis by Coordinating with Transcriptional Repressor Complexes in Response to Hypoxia Signaling Pathway.

ZEB1 EIF4G1

5.16e-045322234026424
Pubmed

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

BAZ1B RBM25

5.97e-045722221555454
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

PNN THOC2 PSMD1 EIF4G1

6.31e-0463822433239621
InteractionSIRT7 interactions

PNN THOC2 MYCBP2 BAZ1B PSMD1 RBM25 EIF4G1 DDX10

6.71e-07744228int:SIRT7
InteractionHERC2 interactions

MYCBP2 PSMD1 CCDC136 RBM25 EIF4G1 HERC1 CLSPN

7.13e-07503227int:HERC2
InteractionCIT interactions

PNN THOC2 CCDC180 BAZ1B RBM25 EIF4G1 HERC1 DDX10 PCMTD1

1.06e-051450229int:CIT
InteractionHECTD1 interactions

PNN THOC2 MYCBP2 BAZ1B RBM25 EIF4G1 DDX10

5.79e-05984227int:HECTD1
InteractionRNF4 interactions

PNN THOC2 BAZ1B PSMD1 RBM25 ZEB1 EIF4G1 SLC12A2

7.48e-051412228int:RNF4
InteractionEED interactions

PNN THOC2 MYCBP2 BAZ1B PSMD1 RBM25 EIF4G1 DDX10

8.81e-051445228int:EED
InteractionCCDC65 interactions

MYCBP2 HERC1

1.03e-0414222int:CCDC65
InteractionLGR4 interactions

THOC2 MYCBP2 RBM25 EIF4G1

1.70e-04262224int:LGR4
InteractionNPM1 interactions

THOC2 BAZ1B PSMD1 WDR87 ZEB1 EIF4G1 DDX10

2.02e-041201227int:NPM1
InteractionCUL7 interactions

PNN THOC2 BAZ1B RBM25 EIF4G1 SLC12A2

2.24e-04845226int:CUL7
InteractionPPWD1 interactions

PNN THOC2 PSMD1

2.45e-04113223int:PPWD1
InteractionDHFR2 interactions

PSMD1 N4BP2 HERC1 SLC12A2

2.47e-04289224int:DHFR2
InteractionUSP29 interactions

ZEB1 CLSPN

3.09e-0424222int:USP29
InteractionSF3B1 interactions

PNN MYCBP2 BAZ1B N4BP2 RBM25

3.17e-04571225int:SF3B1
InteractionOBSL1 interactions

PNN THOC2 BAZ1B RBM25 DDX10 SLC12A2

3.18e-04902226int:OBSL1
InteractionFUBP1 interactions

PNN THOC2 RBM25 EIF4G1

3.19e-04309224int:FUBP1
InteractionPARP1 interactions

PNN MYCBP2 BAZ1B RBM25 ZEB1 DDX10 CLSPN

3.56e-041316227int:PARP1
InteractionBIRC3 interactions

PNN THOC2 BAZ1B PSMD1 RBM25 EIF4G1 DDX10

3.87e-041334227int:BIRC3
InteractionKLF8 interactions

BAZ1B PSMD1 ZEB1 EIF4G1

4.04e-04329224int:KLF8
InteractionNRBP1 interactions

PSMD1 RBM25 EIF4G1

4.12e-04135223int:NRBP1
GeneFamilyWD repeat domain containing

WDR87 HERC1

1.47e-02262132362
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_NEGATIVE

PNN THOC2 N4BP2 RBM25 ZEB1

1.08e-05363225M41103
CoexpressionGSE17721_CTRL_VS_POLYIC_12H_BMDC_UP

MYCBP2 BAZ1B EIF4G1 HERC1

2.16e-05200224M3719
CoexpressionWHITFIELD_CELL_CYCLE_G1_S

PNN CCDC180 CLSPN

1.83e-04133223M2074
CoexpressionRICKMAN_METASTASIS_UP

PNN THOC2 PSMD1 RBM25

1.89e-04350224M9752
CoexpressionTABULA_MURIS_SENIS_KIDNEY_KIDNEY_COLLECTING_DUCT_PRINCIPAL_CELL_AGEING

PNN THOC2 MYCBP2 RBM25

2.97e-04394224MM3724
CoexpressionMONNIER_POSTRADIATION_TUMOR_ESCAPE_UP

PNN RBM25 EIF4G1 SLC12A2

3.39e-04408224M11891
CoexpressionMONNIER_POSTRADIATION_TUMOR_ESCAPE_UP

PNN RBM25 EIF4G1 SLC12A2

3.61e-04415224MM1028
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

THOC2 BAZ1B AK9 RBM25

3.68e-04417224M39224
CoexpressionGSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_DN

RTL5 N4BP2 ZEB1

3.77e-04170223M6762
CoexpressionGSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP

THOC2 RBM25 EIF4G1

3.77e-04170223M5657
CoexpressionGSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP

THOC2 RBM25 EIF4G1

3.84e-04171223M5655
CoexpressionACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP

PNN MYCBP2 PCMTD1

3.97e-04173223M2480
CoexpressionGSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN

MYCBP2 ZEB1 HERC1

4.04e-04174223M6850
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

BAZ1B ZEB1 HERC1

4.46e-04180223M8239
CoexpressionGARY_CD5_TARGETS_DN

PNN PSMD1 RBM25 CLSPN

4.51e-04440224M13893
CoexpressionTABULA_MURIS_SENIS_TRACHEA_T_CELL_AGEING

THOC2 MYCBP2 RBM25 PCMTD1

4.70e-04445224MM3853
CoexpressionGSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN

THOC2 BAZ1B DDX10

4.90e-04186223M8175
CoexpressionGSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN

BAZ1B PSMD1 DDX10

5.97e-04199223M4523
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

MYCBP2 HERC1 SLC12A2

5.97e-04199223M9124
CoexpressionGSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN

CCDC136 HERC1 CLSPN

5.97e-04199223M3070
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

THOC2 RBM25 HERC1

6.06e-04200223M9889
CoexpressionGSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN

BAZ1B PSMD1 EIF4G1

6.06e-04200223M4529
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

THOC2 MYCBP2 BAZ1B ZEB1 DDX10

6.09e-04856225M4500
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

THOC2 GLIPR1L2 RBM25 EIF4G1 HERC1 DDX10 SLC12A2 PCMTD1

7.47e-07795228gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

THOC2 GLIPR1L2 RBM25 EIF4G1 HERC1 DDX10 SLC12A2

8.94e-06776227gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

MYCBP2 BAZ1B B4GALNT4 RYR3 EIF4G1 SLC12A2 PCMTD1

1.26e-05818227gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

THOC2 EIF4G1 HERC1 SLC12A2

1.58e-05150224gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

PNN THOC2 BAZ1B CLSPN

3.69e-05186224Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500

THOC2 GLIPR1L2 EIF4G1 HERC1 SLC12A2

4.00e-05387225gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500

THOC2 RBM25 EIF4G1 HERC1 SLC12A2

4.85e-05403225gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000

THOC2 HERC1 SLC12A2 PCMTD1

8.85e-05233224gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_1000

THOC2 HERC1 SLC12A2

1.07e-0490223gudmap_developingGonad_P2_epididymis_1000_k4
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

THOC2 GLIPR1L2 EIF4G1 HERC1 DDX10 SLC12A2

1.07e-04778226gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

PNN THOC2 RBM25 EIF4G1 HERC1 SLC12A2

1.16e-04790226gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

THOC2 RBM25 EIF4G1 HERC1 SLC12A2 PCMTD1

1.28e-04804226gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

THOC2 RBM25 EIF4G1 HERC1 DDX10 SLC12A2

1.30e-04806226gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_500

THOC2 EIF4G1 SLC12A2

1.34e-0497223gudmap_developingGonad_e18.5_ovary_500_k3
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_1000

THOC2 HERC1 SLC12A2

1.34e-0497223gudmap_developingGonad_e18.5_epididymis_1000_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#3

PNN THOC2 BAZ1B CLSPN

1.58e-04271224Facebase_RNAseq_e10.5_Mandibular Arch_1000_K3
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000

THOC2 EIF4G1 HERC1 SLC12A2

1.68e-04275224gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

PNN THOC2 BAZ1B RBM25 ZEB1 DDX10 CLSPN

1.79e-041241227facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

PNN THOC2 BAZ1B RBM25 ZEB1 DDX10 CLSPN

1.94e-041257227facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

PNN RBM25 CLSPN PCMTD1

2.28e-04298224Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

THOC2 MYCBP2 BAZ1B PSMD1 ZEB1

2.35e-04564225Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000

THOC2 HERC1 SLC12A2

2.96e-04127223gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000

THOC2 EIF4G1 HERC1 SLC12A2

3.10e-04323224gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000

THOC2 HERC1 SLC12A2

3.78e-04138223gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

PNN THOC2 BAZ1B RBM25 ZEB1 DDX10 CLSPN

4.85e-041459227facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000

THOC2 EIF4G1 SLC12A2

4.92e-04151223gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

PNN THOC2 BAZ1B RBM25 ZEB1 DDX10 CLSPN

5.04e-041468227facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

PNN MYCBP2 BAZ1B PCMTD1

5.44e-04375224gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

PNN RBM25 ZEB1 HERC1 CLSPN PCMTD1

5.71e-041060226facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

MYCBP2 BAZ1B EIF4G1 PCMTD1

6.01e-04385224gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500

THOC2 GLIPR1L2 EIF4G1 HERC1

6.13e-04387224gudmap_developingGonad_e16.5_ovary_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#1_top-relative-expression-ranked_1000

MYCBP2 BAZ1B PCMTD1

7.30e-04173223gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k1
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

THOC2 EIF4G1 HERC1 DDX10 SLC12A2

9.75e-04770225gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4

PNN BAZ1B CLSPN

9.87e-04192223Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_1000

MYCBP2 BAZ1B PCMTD1

1.13e-03201223gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k5
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

THOC2 RBM25 EIF4G1 HERC1 SLC12A2

1.14e-03797225gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

THOC2 RBM25 EIF4G1 HERC1 SLC12A2

1.15e-03799225gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

THOC2 RBM25 EIF4G1 HERC1 SLC12A2

1.16e-03801225gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000

MYCBP2 BAZ1B RYR3 SLC12A2 PCMTD1

1.20e-03806225DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

MYCBP2 BAZ1B B4GALNT4 RYR3 PCMTD1

1.20e-03806225gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

PNN BAZ1B RBM25 CLSPN

1.25e-03469224Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000

THOC2 RBM25 EIF4G1 HERC1 SLC12A2

1.26e-03815225gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

MYCBP2 BAZ1B RYR3 SLC12A2 PCMTD1

1.28e-03818225DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000

THOC2 EIF4G1 SLC12A2

1.28e-03210223gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

PNN THOC2 RBM25 ZEB1 CLSPN PCMTD1

1.37e-031252226facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500

PNN THOC2 BAZ1B CLSPN

1.49e-03492224Facebase_RNAseq_e10.5_Mandibular Arch_500
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000

THOC2 EIF4G1 SLC12A2

1.56e-03225223gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000

MYCBP2 BAZ1B SLC12A2

1.58e-03226223gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

THOC2 EIF4G1 PCMTD1

1.66e-03230223gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

PNN N4BP2 RBM25 CLSPN

1.99e-03532224Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

PNN RBM25 CLSPN

2.01e-03246223Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_1000

RYR3 PCMTD1

2.05e-0365222DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_1000
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500

EIF4G1 SLC12A2

2.05e-0365222gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

PNN RBM25 ZEB1 HERC1 CLSPN PCMTD1

2.55e-031414226facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

BAZ1B ZEB1 SLC12A2 CLSPN

2.99e-03595224Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

PNN BAZ1B CLSPN

3.23e-03291223Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#5_top-relative-expression-ranked_1000

BAZ1B PCMTD1

3.39e-0384222gudmap_developingKidney_e15.5_Endothelial cells_1000_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

PNN BAZ1B ZEB1 CLSPN

3.65e-03629224Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

PNN THOC2 RBM25 ZEB1 CLSPN

3.79e-081972250fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PNN MYCBP2 RBM25 SLC12A2

2.55e-061992243d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

RBM25 ZEB1 HERC1

3.90e-05135223ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC136 AK9 RYR3

5.77e-0515422316fdafb5c64d2db321554f87129a962d113f1668
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

CCDC180 RTL5 ZEB1

6.35e-05159223037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCellFLU-Healthy-3|FLU / Virus stimulation, Condition and Cluster

CCDC180 CCDC136 CLSPN

8.15e-0517322332b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCellFLU-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

CCDC180 CCDC136 CLSPN

8.15e-0517322326e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

CCDC136 B4GALNT4 HERC1

8.58e-05176223d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCellC_00|World / shred on cell type and cluster

PNN RBM25 SLC12A2

9.02e-05179223da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B SLC12A2 CLSPN

1.01e-0418622315ab6666748a641226e42e6ca6eeaf186a501c95
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B SLC12A2 CLSPN

1.01e-041862234ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

PNN BAZ1B RBM25

1.11e-041922239cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PNN RBM25 HERC1

1.20e-0419722357ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellPBMC_fresh-frozen|World / Compartment, severity and other cell annotations on 10x 3' data (130k)

PNN MYCBP2 RBM25

1.22e-04198223dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

MYCBP2 PSMD1 RBM25

1.22e-0419822376d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PNN RBM25 HERC1

1.23e-04199223f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmegakaryocytic-CD34+_Megakaryoblast|megakaryocytic / Lineage and Cell class

PNN MYCBP2 RBM25

1.23e-0419922399a65887d3c8a2cde26693dd74404b101bba9d58
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

PNN THOC2 RBM25

1.23e-04199223a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PNN MYCBP2 RBM25

1.25e-0420022312f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19|World / Disease, condition lineage and cell class

PNN MYCBP2 RBM25

1.25e-042002237dec470c379cd89f05a0f37c8628b21f136e52f0
ComputationalNeighborhood of RBBP6

PNN THOC2 RBM25

7.22e-0570133GNF2_RBBP6
ComputationalNeighborhood of MAX

MYCBP2 RBM25

6.16e-0431132GCM_MAX
Drugphenethyl isothiocyanate

THOC2 BAZ1B EIF4G1 SLC12A2 CLSPN PCMTD1

1.69e-06401226ctd:C058305
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA

THOC2 MYCBP2 RBM25 EIF4G1

2.31e-05177224985_DN
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A

MYCBP2 RBM25 ZEB1 EIF4G1

2.42e-051792244585_DN
Diseasedisease progression measurement

RYR3 HERC1

8.61e-0461212EFO_0008336
DiseaseMalignant neoplasm of breast

N4BP2 ZEB1 DDX10 CLSPN

6.37e-031074214C0006142
DiseaseC-reactive protein measurement

THOC2 BAZ1B RBM25 ZEB1

9.53e-031206214EFO_0004458

Protein segments in the cluster

PeptideGeneStartEntry
EEVDEEKKMVEEAKV

BAZ1B

1131

Q9UIG0
EEEEEKLEEEKEEKE

CCDC180

776

Q9P1Z9
QEKEEKREEPMEEEE

RBM25

591

P49756
EEKEEEKKEKEEMEM

GLIPR1L2

301

Q4G1C9
EREEEEEETQKEKME

GLIPR1L2

326

Q4G1C9
ENEMREEKESKEEEK

HERC1

2266

Q15751
EKMEEDNKEEEEKDH

PCMTD1

306

Q96MG8
ALDMEKESEEKEEKE

PNN

451

Q9H307
DDDEVFEKKQKEMDE

EIF4G1

856

Q04637
EDDEEEMEEKLAKAK

DDX10

586

Q13206
EMKKKEEKEEEEEEE

RTL5

386

Q5HYW3
EEKEEEEEEEMKQKE

RTL5

391

Q5HYW3
EEEEEMKQKEEEEEI

RTL5

396

Q5HYW3
EEEEEEEGEDKMKER

AK9

911

Q5TCS8
KEKKEEEKMEVDEAE

PSMD1

846

Q99460
EEKMEVDEAEKKEEK

PSMD1

851

Q99460
MDEDLEEELDEKDEK

MYCBP2

736

O75592
MKMDKEEGDEDEEDE

B4GALNT4

406

Q76KP1
DGLAKEEEKKEEMEE

CCDC136

1031

Q96JN2
EEEKKEEMEEEKKQV

CCDC136

1036

Q96JN2
EKEEKEEELEEEEEK

CLSPN

651

Q9HAW4
EKMDEREKEKEKEEE

THOC2

321

Q8NI27
EDEDKEKTFEEKEME

RYR3

3596

Q15413
DDKEQDIADKMKEDE

SLC12A2

1116

P55011
SEKEEEEEDKEMEEL

ZEB1

1036

P37275
EEEDKEMEELQEEKE

ZEB1

1041

P37275
EKEEVFEEKEEIMSE

WDR87

2301

Q6ZQQ6
DEEEFMNEDEKEMKE

N4BP2

1326

Q86UW6