Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycine hydroxymethyltransferase activity	SHMT1 SHMT2	2.19e-05	2	94	2	GO:0004372
GeneOntologyMolecularFunction	threonine aldolase activity	SHMT1 SHMT2	6.56e-05	3	94	2	GO:0004793
GeneOntologyMolecularFunction	L-allo-threonine aldolase activity	SHMT1 SHMT2	6.56e-05	3	94	2	GO:0008732
GeneOntologyMolecularFunction	ferrous iron transmembrane transporter activity	SLC39A14 SLC25A28	3.25e-04	6	94	2	GO:0015093
GeneOntologyMolecularFunction	hydroxymethyl-, formyl- and related transferase activity	SHMT1 SHMT2	6.03e-04	8	94	2	GO:0016742
GeneOntologyBiologicalProcess	glycine biosynthetic process from serine	SHMT1 SHMT2	2.05e-05	2	94	2	GO:0019264
Domain	SHMT	SHMT1 SHMT2	2.51e-05	2	94	2	PF00464
Domain	Ser_HO-MeTrfase_PLP_BS	SHMT1 SHMT2	2.51e-05	2	94	2	IPR019798
Domain	SHMT	SHMT1 SHMT2	2.51e-05	2	94	2	PS00096
Domain	Ser_HO-MeTrfase	SHMT1 SHMT2	2.51e-05	2	94	2	IPR001085
Domain	BAT2_N	PRRC2C PRRC2B	7.49e-05	3	94	2	PF07001
Domain	BAT2_N	PRRC2C PRRC2B	7.49e-05	3	94	2	IPR009738
Domain	PRRC2	PRRC2C PRRC2B	7.49e-05	3	94	2	IPR033184
Domain	Ig_I-set	HMCN1 PXDNL CD101 IGDCC3 ROBO3 ADAMTSL3	3.97e-04	190	94	6	IPR013098
Domain	I-set	HMCN1 PXDNL CD101 IGDCC3 ROBO3 ADAMTSL3	3.97e-04	190	94	6	PF07679
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	KMT2D TCF20 EP400 FUBP1 NOL6 WDR46 MED14 NUP188 ARID1A	4.62e-07	341	96	9	32971831
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	FOXJ2 HIPK3 TET2 CDYL2 TLN2 SLC39A14 PITPNC1 NHEJ1 ARID1A SLC25A28	2.40e-06	536	96	10	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	FOXJ2 HIPK3 TET2 CDYL2 TLN2 SLC39A14 PITPNC1 NHEJ1 ARID1A SLC25A28	2.48e-06	538	96	10	10512203
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2D TCF20 EP400 PRRC2C DBNL MED14 AMOTL2 PATJ ARID1A PRRC2B	2.96e-06	549	96	10	38280479
Pubmed	Large-scale concatenation cDNA sequencing.	FOXJ2 MED14 ADCK2 TLN2 RALGAPA2 RFNG FBXO21 HMGCLL1 MAPK8IP2 IP6K2	4.00e-06	568	96	10	9110174
Pubmed	A "double adaptor" method for improved shotgun library construction.	FOXJ2 MED14 ADCK2 TLN2 RALGAPA2 RFNG FBXO21 HMGCLL1 MAPK8IP2 IP6K2	4.39e-06	574	96	10	8619474
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	KMT2D TCF20 PRRC2C FUBP1 GLIS3 NUP43 NUP188 ARID1A PRRC2B	5.10e-06	457	96	9	32344865
Pubmed	Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.	SHMT1 SHMT2	7.54e-06	2	96	2	29073064
Pubmed	Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene.	SHMT1 SHMT2	7.54e-06	2	96	2	9573390
Pubmed	Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.	SHMT1 SHMT2	7.54e-06	2	96	2	30500180
Pubmed	Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells.	SHMT1 SHMT2	7.54e-06	2	96	2	17482557
Pubmed	Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization.	SHMT1 SHMT2	7.54e-06	2	96	2	8505317
Pubmed	How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.	SHMT1 SHMT2	7.54e-06	2	96	2	25619277
Pubmed	The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR.	SHMT1 SHMT2	7.54e-06	2	96	2	11516159
Pubmed	Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?	SHMT1 SHMT2	7.54e-06	2	96	2	11386852
Pubmed	TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease.	GPNMB TFE3	7.54e-06	2	96	2	31043488
Pubmed	Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.	SHMT1 SHMT2	7.54e-06	2	96	2	27530298
Pubmed	Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.	SHMT1 SHMT2	7.54e-06	2	96	2	22220685
Pubmed	Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders.	TET2 KMT2D	7.54e-06	2	96	2	31311407
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TET2 KMT2D TCF20 EP400 MED14 ARID1A PRRC2B	9.91e-06	268	96	7	33640491
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DGCR2 KMT2D EP400 MED14 TLN2 NUP188 ARID1A RALGAPA2 UVRAG SOWAHB TFE3 PRRC2B PCNT	1.10e-05	1105	96	13	35748872
Pubmed	Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells.	KMT2D ARID1A	2.26e-05	3	96	2	27387124
Pubmed	Proteomic identification of mitochondrial targets of arginase in human breast cancer.	SHMT1 SHMT2	2.26e-05	3	96	2	24223914
Pubmed	The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.	TET2 KMT2D	2.26e-05	3	96	2	26551667
Pubmed	Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitus.	PITPNC1 LY75	2.26e-05	3	96	2	22865700
Pubmed	Affinity properties of phosvitin: interaction of phosvitin with serine hydroxymethyl transferase.	SHMT1 SHMT2	2.26e-05	3	96	2	10549165
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	TCF20 PRRC2C DBNL NUP43 ARID1A	2.41e-05	123	96	5	26912792
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TCF20 EP400 FUBP1 PAFAH1B3 NOL6 MPZL1 WDR46 NUP43 SHMT2 NUP188 PCNT STAU1	2.56e-05	1024	96	12	24711643
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CDC42BPG EDC3 FBXO10 RNF112 IGDCC3 NUP188 CFAP57 AMOTL2 QRICH2 PLXNB3	3.72e-05	736	96	10	29676528
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	KMT2D EP400 MED14 ARID1A	4.11e-05	69	96	4	28481362
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2D ARID1A	4.51e-05	4	96	2	34645806
Pubmed	Beyond conventional chemotherapy: Emerging molecular targeted and immunotherapy strategies in urothelial carcinoma.	KMT2D ARID1A	4.51e-05	4	96	2	26138514
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TXNRD1 TET2 KMT2D TCF20 EP400 PRRC2C FUBP1 CDKN2AIP MED14 ARID1A PRRC2B STAU1	5.26e-05	1103	96	12	34189442
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 KMT2D TCF20 EP400 NUP43 ARID1A PRRC2B	5.55e-05	351	96	7	38297188
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	KMT2D TCF20 NUP188 ARID1A	6.65e-05	78	96	4	28611094
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	KMT2D TCF20 NOL6 ADCK2 ARID1A ZNF251 ABCC6 TFE3 PRRC2B	6.98e-05	638	96	9	31182584
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TCF20 PRRC2C NOL6 WDR46 NUP188 ARID1A PRRC2B PCNT STAU1	8.33e-05	653	96	9	22586326
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	KMT2D TCF20 EP400 ARID1A	8.48e-05	83	96	4	28794006
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	KMT2D EP400 MED14 VRTN ARID1A	1.03e-04	167	96	5	20362541
Pubmed	Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.	AMOTL2 PATJ	1.12e-04	6	96	2	17397395
Pubmed	SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.	SHMT1 SHMT2	1.12e-04	6	96	2	19513116
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TET2 KMT2D TCF20 EP400 SHMT1 SHMT2 ARID1A	1.21e-04	398	96	7	35016035
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TCF20 EP400 PRRC2C SLC39A14 PLXNB3 PRRC2B PCNT	1.39e-04	407	96	7	12693553
Pubmed	TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis.	TRIM67 PLPPR4	1.57e-04	7	96	2	22337885
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SP3 SYNPO2 EP400 GLIS3 PATJ UVRAG PCNT	1.95e-04	430	96	7	35044719
Pubmed	Impaired motor coordination in mice that lack punc.	LOXL1 IGDCC3	2.09e-04	8	96	2	11486040
Pubmed	AMOTL2 mono-ubiquitination by WWP1 promotes contact inhibition by facilitating LATS activation.	AMOTL2 PATJ	2.09e-04	8	96	2	34404733
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	EP400 NOL6 MED14 NUP43 NUP188 ARID1A STAU1	2.24e-04	440	96	7	34244565
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	ADAMTS10 TET2 LOXL1 ADAMTSL3 TNS1	2.28e-04	198	96	5	20881960
Pubmed	Functional selectivity of recombinant mammalian SWI/SNF subunits.	ARID1A TFE3	4.08e-04	11	96	2	11018012
Pubmed	ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.	SHMT1 SHMT2	4.08e-04	11	96	2	31772275
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TET2 EP400 FBXO21 PLXNB3	4.75e-04	130	96	4	12421765
Pubmed	Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.	TET2 NHEJ1 ADAMTSL3 TNS1	5.62e-04	136	96	4	25429064
Pubmed	Human transcription factor protein interaction networks.	TET2 KMT2D EDC3 TCF20 EP400 PRRC2C FUBP1 ETV4 ARID1A TFE3 PRRC2B STAU1	5.71e-04	1429	96	12	35140242
Pubmed	A physical map of the mouse shaker-2 region contains many of the genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2).	RNF112 SHMT1	5.77e-04	13	96	2	10049592
Pubmed	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.	KMT2D EP400	5.77e-04	13	96	2	16510874
Pubmed	Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line.	SP3 PRRC2C	6.71e-04	14	96	2	15747776
Pubmed	HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.	HIPK3 GLIS3	6.71e-04	14	96	2	26147758
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 DGCR2 EP400 PLPPR4 MARCHF6 NUP188 AMOTL2	6.72e-04	529	96	7	14621295
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	HMCN1 PRRC2C FUBP1 STAU1	7.53e-04	147	96	4	28977470
Pubmed	Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.	KMT2D EP400	7.73e-04	15	96	2	16510875
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	KMT2D EP400 MED14	7.86e-04	65	96	3	22496869
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ZMYND19 EDC3 CYP27B1 DBNL SHMT1 SHMT2 NUP188 PATJ TNS1 PCNT	8.30e-04	1084	96	10	11544199
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	TET2 CDKN2AIP PRRC2B IP6K2	8.53e-04	152	96	4	38360978
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	TCF20 HMCN1 NUP188 ZNF251	8.53e-04	152	96	4	34299191
Pubmed	TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.	TCF20 NUP43 NUP188 AMOTL2	8.53e-04	152	96	4	28192407
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	TET2 PRRC2C FUBP1 CDKN2AIP SHMT2 PRRC2B STAU1	8.53e-04	551	96	7	34728620
Pubmed	The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.	AMOTL2 PATJ	8.82e-04	16	96	2	18824598
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	HIPK3 ADAMTS10 ENPP7 FUBP1 SHMT1 SHMT2 ARID1A POLR3A	9.49e-04	730	96	8	34857952
Pubmed	A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.	AMOTL2 PATJ	9.98e-04	17	96	2	16678097
Pubmed	A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses.	SHMT1 SHMT2	9.98e-04	17	96	2	24075985
Pubmed	A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.	PRRC2C NOL6 WDR46 STAU1	1.08e-03	162	96	4	31363146
Pubmed	Aerobic glycolysis tunes YAP/TAZ transcriptional activity.	FUBP1 AMOTL2 PATJ ARID1A	1.08e-03	162	96	4	25796446
Pubmed	Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.	TET2 ITGA2B	1.12e-03	18	96	2	20887958
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	EDC3 EP400 PRRC2C CDKN2AIP DBNL SHMT2 PRRC2B PCNT STAU1	1.13e-03	934	96	9	33916271
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	CDC42BPG CDKN2AIP SLC39A14 PRRC2B STAU1	1.15e-03	283	96	5	21903422
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS10 HMCN1 ADAMTSL3	1.19e-03	75	96	3	20637190
Pubmed	Functional proteomics mapping of a human signaling pathway.	HIPK3 DGCR2 KMT2D GORASP1 GPNMB ZNF251 STAU1	1.28e-03	591	96	7	15231748
Pubmed	Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.	TET2 TCF20	1.39e-03	20	96	2	20564319
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRIM67 TCF20 PLPPR4 PRRC2C TLN2 TNS1 MAPK8IP2 PRRC2B PCNT	1.39e-03	963	96	9	28671696
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	EDC3 EP400 VWA5A FUBP1 CDKN2AIP STAU1	1.47e-03	444	96	6	34795231
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	DGCR2 PRRC2C AMOTL2 PATJ ARID1A PRRC2B STAU1	1.60e-03	615	96	7	31048545
Pubmed	Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.	FBXO21 PCNT	1.68e-03	22	96	2	26631746
Pubmed	The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.	AMOTL2 PATJ	1.68e-03	22	96	2	27521426
Pubmed	The apical complex couples cell fate and cell survival to cerebral cortical development.	PATJ PCNT	1.68e-03	22	96	2	20399730
Pubmed	Genome-wide association analysis identifies 20 loci that influence adult height.	NHEJ1 ADAMTSL3	1.68e-03	22	96	2	18391952
Pubmed	Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.	GORASP1 MAPK8IP2	1.68e-03	22	96	2	15767678
Pubmed	PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA.	PRRC2C PRRC2B	1.68e-03	22	96	2	38507412
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	KMT2D EDC3 SBSN STAU1	1.72e-03	184	96	4	32908313
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	ENPP7 MPZL1 ITGA2B SLC39A14 PCDH12 SBSN	1.76e-03	460	96	6	20562862
Pubmed	14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.	TXNRD1 EDC3 DBNL OPLAH	1.79e-03	186	96	4	14744259
Pubmed	Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.	AMOTL2 PATJ	1.84e-03	23	96	2	26933062
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	KMT2D EP400	1.84e-03	23	96	2	9225980
Pubmed	A protein interaction landscape of breast cancer.	FUBP1 CDKN2AIP NUP188 AMOTL2 ARID1A SBSN STAU1	1.90e-03	634	96	7	34591612
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ADAMTS10 FBXO10 FUBP1 CDKN2AIP SHMT2 NUP188 ROBO3 PRRC2B IP6K2 OPLAH	1.94e-03	1215	96	10	15146197
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	TXNRD1 EDC3 TCF20 EP400 FUBP1 CDKN2AIP MED14 NHEJ1 POLR3A	1.98e-03	1014	96	9	32416067
Pubmed	Genomic screen for genes involved in mammalian craniofacial development.	PAFAH1B3 IGDCC3	2.00e-03	24	96	2	12533789
Pubmed	Genome-wide association study of proneness to anger.	HIPK3 STAU1	2.00e-03	24	96	2	24489884
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	TCF20 EP400 NOL6 TLN2 ARID1A SBSN	2.01e-03	472	96	6	38943005
Pubmed	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.	TXNRD1 HIPK3 TCF20 FUBP1 DBNL	2.17e-03	327	96	5	15592455
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HMCN1 PXDNL CD101 IGDCC3 ROBO3 ADAMTSL3	9.18e-06	161	55	6	593
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	SYNPO2 HMCN1 PLPPR4 TLN2 ADAMTSL3 HMGCLL1	3.23e-06	187	96	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
Disease	Sezary Syndrome	TET2 KMT2D ARID1A	8.94e-05	27	95	3	C0036920
Disease	vital capacity	ADAMTS10 TET2 TCF20 HMCN1 LOXL1 GLIS3 VRTN PATJ ADAMTSL3 TNS1 DNM1P46 HMGCLL1 STAU1	1.65e-04	1236	95	13	EFO_0004312
Disease	stomach cancer (is_marker_for)	TET2 KMT2D FUBP1 ARID1A	1.17e-03	142	95	4	DOID:10534 (is_marker_for)
Disease	T-Cell Lymphoma	KMT2D ARID1A	1.20e-03	16	95	2	C0079772
Disease	Moyamoya Disease	ABCC6 PCNT	1.35e-03	17	95	2	C0026654
Disease	esophagus squamous cell carcinoma (is_marker_for)	TET2 KMT2D FUBP1	1.78e-03	74	95	3	DOID:3748 (is_marker_for)
Disease	Colorectal Neoplasms	TXNRD1 TET2 GPNMB ARID1A ABCC6	2.05e-03	277	95	5	C0009404
Disease	cup-to-disc ratio measurement	LOXL1 MPZL1 AMOTL2 ADAMTSL3 MN1 IP6K2	2.70e-03	430	95	6	EFO_0006939
Disease	smoking status measurement, chronic obstructive pulmonary disease	TET2 GLIS3 TNS1	2.91e-03	88	95	3	EFO_0000341, EFO_0006527

Protein segments in the cluster

Peptide	Gene	Start	Entry
GQEHQGGENHLAENT	AMOTL2	76	Q9Y2J4
RLEVGHQGVVFQHPG	EP400	521	Q96L91
HQGVVFQHPGADAGV	EP400	526	Q96L91
FVHADLHPGNILVQG	ADCK2	441	Q7Z695
NGILNGGHQNVFPNH	ANKRD10	191	Q9NXR5
GGHQNVFPNHISVGT	ANKRD10	196	Q9NXR5
PHGDQGVHLLGAAVQ	DNM1P46	96	Q6ZS02
CNFENGHIQVHGPGT	FBXO10	206	Q9UK96
NGTGQSHHNVFPDGK	GPNMB	146	Q14956
IVNHSGHGNAIPENG	ADAMTS10	321	Q9H324
GHGNAIPENGVANHD	ADAMTS10	326	Q9H324
QAGQPAVDQGGVNGH	ETV4	236	P43268
HPNQQHVVATGGQDG	NUP43	226	Q8NFH3
QHGLIQPGTGQHDLV	QRICH2	471	Q9H0J4
DQHGLVQPGVDQHGL	QRICH2	601	Q9H0J4
NPHNVVNVAGGFSLH	RFNG	286	Q9Y644
NFAVFPSLQGGPHNH	SHMT2	316	P34897
TNFNHLVHVGPANGR	CDC42BPG	1441	Q6DT37
GNEAHLFILNPHTGQ	PCDH12	641	Q9NPG4
HALNFGIGGDGTQHV	PAFAH1B3	66	Q15102
AAVFHQQHGGQQSPG	ARID1A	166	O14497
LHELQVQGAAHFGPV	CYP27B1	61	O15528
HIQTLDPGQHGAVGY	FBXO21	456	O94952
DPGQHGAVGYLVQHT	FBXO21	461	O94952
FHVHPQATVGEEGGV	IGDCC3	141	Q8IVU1
GVLLEPFVHQVGGHS	IP6K2	16	Q9UHH9
GFHHGDGPGNAVQEI	FUBP1	176	Q96AE4
NGGHLFAAVNGNVIH	CFAP57	481	Q96MR6
QFLGSVEVPCHQGNG	MAPK8IP2	686	Q13387
VLVHGQQAQPGQGSD	LOXL1	21	Q08397
LVAVGGFSPNVNHGE	CDKN2AIP	451	Q9NXV6
HGSQGQVYHSQQVGP	PLXNB3	426	Q9ULL4
LHGLQQQHPAFSGVA	NOL6	841	Q9H6R4
DVIHPGGNSHIANGA	SLC25A28	161	Q96A46
GGHLASVHNQNGQLF	LY75	1426	O60449
AAHQAILQQGGPVGF	MARCHF6	606	O60337
VYVGGGQIIHLHQGE	LRATD1	146	Q96KN4
GDNQHFGDLHQTELG	EDC3	71	Q96F86
NHFLTQTGHVPPQGG	FOXJ2	471	Q9P0K8
QGPVIYAQLDHSGGH	MPZL1	236	O95297
PAAGSGHLTVGQQQQ	RALGAPA2	746	Q2PPJ7
VHHGIPLQAGTAQFG	HIPK3	601	Q9H422
VAHELQGVHQGEFGS	PCNT	1046	O95613
GFHLHGVQENSPAQQ	GORASP1	16	Q9BQQ3
GSLQIAFVQPGDAGH	HMCN1	4131	Q96RW7
IPHQGVQVEGDGFSH	MED14	666	O60244
DGGDPVHSGNLHIQV	PCDHGA3	216	Q9Y5H0
HLNQVGHTGGLEQVE	OTULIN	276	Q96BN8
LGELLQGFAQHGHTQ	PXDNL	191	A1KZ92
IGCNVTGHQGPSEQH	CD101	41	Q93033
QQLEHGGLQPGLVNH	GLIS3	241	Q8NEA6
GGDPSHFHAVNVAQP	DGCR2	91	P98153
GHQDIPGVGNIHSGA	CENATAC	226	Q86UT8
HGRINVQFNNGEHGF	ENPP7	341	Q6UWV6
VGVGRGNVTQHVQGH	SLC39A14	71	Q15043
EKFGQGVHHTAGQVG	SBSN	276	Q6UWP8
GQFGQGVHHTLEQAG	SBSN	456	Q6UWP8
DHHIQGQGLSGQGLC	DBNL	361	Q9UJU6
SELHAGGLQAQPVHG	MN1	76	Q10571
QGGPHNHAIAGVAVA	SHMT1	301	P34896
LTPNLQGFHHAVAAG	HMGCLL1	151	Q8TB92
SLNGGHANVHPSQEQ	UVRAG	571	Q9P2Y5
GTNNVHPPQHVVGNQ	NXPE4	521	Q6UWF7
HVGQHVFNQVIGPGG	ABCC6	786	O95255
QFQIQHLGADLHPGD	OPLAH	801	O14841
QAPNVAHELSGGCHG	PTCH2	271	Q9Y6C5
INGSSAHHQEGVPNG	PRRC2C	1601	Q9Y520
AHHQEGVPNGTGQKN	PRRC2C	1606	Q9Y520
GPEVHPGANFIQQRH	POLR3A	411	O14802
VQVGQKHQGAGDPHT	NHEJ1	226	Q9H9Q4
ELHNNGPGTVNGLHL	ITGA2B	816	P08514
NQHTLLFGGDTNPVH	PDK3	166	Q15120
ISQQVPAGANGLAGH	SOWAHB	466	A6NEL2
GNGSHQPGLDLNDHV	CDYL2	171	Q8N8U2
ADHVTAGANGQHGPQ	TEX44	171	Q53QW1
VGFHVLGPNAGEVTQ	TXNRD1	586	Q16881
SRVGVNGDHHGPGNQ	PLPPR4	486	Q7Z2D5
GQQQGPTAFSHVDGV	TRIM67	736	Q6ZTA4
HRGGVAPGFQVVHLN	ZMYND19	76	Q96E35
EVSHGLGHVPQQNGF	SYNPO2	556	Q9UMS6
SHPNKAGQGHVGNIF	RNF112	321	Q9ULX5
TFHVGGGPAQNAPHQ	TFE3	476	P19532
VPEVAQAVGVSQGHH	STAU1	421	O95793
IPGSAAYHNGHIQVN	PATJ	401	Q8NI35
GGGGHGEYLQQQQQH	SP3	26	Q02447
GEELQTFHGGFPQHP	ROBO3	1026	Q96MS0
SGRHVVPAQVHVNGG	TNS1	476	Q9HBL0
VVQNEPFEDPHHGNG	PITPNC1	41	Q9UKF7
GENQVEHSPHFLGPQ	TRAV7	21	A0A075B6U4
PLEQALSQHGAHGNN	NUP188	836	Q5SRE5
NVQDAGAPGGHTQNL	PRRC2B	836	Q5JSZ5
QHSPGFGENHLVQLI	VWA5A	671	O00534
GSEGHVGQFQAQHSG	TCF20	131	Q9UGU0
NPYNAVIHLGHSNGT	WDR46	326	O15213
QIPTGEKHGRAFNHG	ZNF251	536	Q9BRH9
GGFQAQIQFGPHVEH	TLN2	241	Q9Y4G6
EAQQAQSPQGYTHHG	WEE2	516	P0C1S8
EGALQEGATAQGQPH	VRTN	606	Q9H8Y1
IHNHANVFPVPDQGG	TET2	921	Q6N021
QQAVYGHVHLGTGDP	TFR2	316	Q9UP52
INHRGEHVGGCNPQL	ADAMTSL3	506	P82987
VTHQGGPVFVNHRTN	GARIN5B	51	Q8N5Q1
GGLVFHAIGQLLPHQ	KMT2D	5181	O14686