Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	1.75e-09	279	83	12	GO:0005096
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine N-sulfotransferase activity	NDST3 NDST1 NDST4	2.76e-07	4	83	3	GO:0015016
GeneOntologyMolecularFunction	N-acetylglucosamine deacetylase activity	NDST3 NDST1 NDST4	2.76e-07	4	83	3	GO:0050119
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	1.19e-06	507	83	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	1.19e-06	507	83	12	GO:0030695
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	1.64e-05	656	83	12	GO:0008047
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	NDST3 NDST1 NDST4	3.04e-05	15	83	3	GO:0034483
GeneOntologyMolecularFunction	heparan sulfate N-deacetylase activity	NDST3 NDST1	5.11e-05	3	83	2	GO:0102140
GeneOntologyMolecularFunction	neuropeptide receptor activity	GALR3 MRGPRX1 MRGPRX3 MRGPRX4	6.96e-05	53	83	4	GO:0008188
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	GALR3 AVPR1A MRGPRX1 MRGPRX3 MRGPRX4	2.33e-04	133	83	5	GO:0008528
GeneOntologyMolecularFunction	peptide receptor activity	GALR3 AVPR1A MRGPRX1 MRGPRX3 MRGPRX4	2.95e-04	140	83	5	GO:0001653
GeneOntologyMolecularFunction	protein prenyltransferase activity	FNTB RABGGTA	4.70e-04	8	83	2	GO:0008318
GeneOntologyMolecularFunction	neuropeptide binding	MRGPRX1 MRGPRX3 MRGPRX4	4.86e-04	37	83	3	GO:0042923
GeneOntologyMolecularFunction	molecular function activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D GPNMB TBC1D3I GDF1 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	5.23e-04	1233	83	14	GO:0140677
GeneOntologyMolecularFunction	DEAD/H-box RNA helicase binding	SMAD3 SP7	6.03e-04	9	83	2	GO:0017151
GeneOntologyMolecularFunction	deacetylase activity	NDST3 NDST1 NDST4	6.12e-04	40	83	3	GO:0019213
GeneOntologyMolecularFunction	co-SMAD binding	SMAD2 SMAD3	1.10e-03	12	83	2	GO:0070410
GeneOntologyMolecularFunction	sulfotransferase activity	NDST3 NDST1 NDST4	1.55e-03	55	83	3	GO:0008146
GeneOntologyMolecularFunction	O-acyltransferase activity	MOGAT1 PORCN SOAT2	1.90e-03	59	83	3	GO:0008374
GeneOntologyMolecularFunction	I-SMAD binding	SMAD2 SMAD3	2.23e-03	17	83	2	GO:0070411
GeneOntologyMolecularFunction	prenyltransferase activity	FNTB RABGGTA	2.50e-03	18	83	2	GO:0004659
GeneOntologyMolecularFunction	transferase activity, transferring sulphur-containing groups	NDST3 NDST1 NDST4	3.63e-03	74	83	3	GO:0016782
GeneOntologyMolecularFunction	carboxylic ester hydrolase activity	NDST3 NDST1 ABHD15 VARS1	4.18e-03	157	83	4	GO:0052689
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	NDST3 NDST1 NDST4	4.68e-03	81	83	3	GO:0016811
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.49e-13	109	82	11	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.39e-09	244	82	11	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	8.83e-08	335	82	11	GO:0043087
GeneOntologyBiologicalProcess	response to chloroquine	MRGPRX1 MRGPRX3 MRGPRX4	6.02e-07	5	82	3	GO:1902349
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B SMAD3 TBC1D3K TBC1D3F	6.28e-07	499	82	12	GO:0051345
GeneOntologyBiologicalProcess	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	NDST3 NDST1 NDST4	3.34e-06	8	82	3	GO:0015014
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D WFIKKN1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B SMAD3 TBC1D3K TBC1D3F SP7	8.58e-06	878	82	14	GO:0051336
GeneOntologyBiologicalProcess	heparin biosynthetic process	NDST3 NDST1 NDST4	9.77e-06	11	82	3	GO:0030210
GeneOntologyBiologicalProcess	heparin metabolic process	NDST3 NDST1 NDST4	3.96e-05	17	82	3	GO:0030202
GeneOntologyBiologicalProcess	negative regulation of nervous system process	AVPR1A MTNR1B MTMR2	1.15e-04	24	82	3	GO:0031645
GeneOntologyBiologicalProcess	negative regulation of cytosolic calcium ion concentration	MTNR1B SMPD3 SMAD3	1.31e-04	25	82	3	GO:0051481
GeneOntologyBiologicalProcess	behavior	MAP1A GALR3 AVPR1A MRGPRX1 MTNR1B MRGPRX3 MRGPRX4 SPG11 MFSD8 ACSS2 EN1 CRBN	2.00e-04	891	82	12	GO:0007610
GeneOntologyBiologicalProcess	polysaccharide biosynthetic process	NDST3 NDST1 NDST4 SMPD3	2.39e-04	76	82	4	GO:0000271
GeneOntologyBiologicalProcess	glycosaminoglycan biosynthetic process	NDST3 NDST1 NDST4 SMPD3	2.39e-04	76	82	4	GO:0006024
GeneOntologyBiologicalProcess	chemosensory behavior	MRGPRX1 MRGPRX3 MRGPRX4	2.51e-04	31	82	3	GO:0007635
GeneOntologyBiologicalProcess	aminoglycan biosynthetic process	NDST3 NDST1 NDST4 SMPD3	2.92e-04	80	82	4	GO:0006023
GeneOntologyBiologicalProcess	heparan sulfate proteoglycan biosynthetic process	NDST3 NDST1 NDST4	3.62e-04	35	82	3	GO:0015012
GeneOntologyCellularComponent	neuronal cell body membrane	SLC6A2 MRGPRX1 MRGPRX3 MRGPRX4	2.42e-05	43	82	4	GO:0032809
GeneOntologyCellularComponent	cell body membrane	SLC6A2 MRGPRX1 MRGPRX3 MRGPRX4	3.45e-05	47	82	4	GO:0044298
GeneOntologyCellularComponent	heteromeric SMAD protein complex	SMAD2 SMAD3	4.19e-04	8	82	2	GO:0071144
GeneOntologyCellularComponent	SMAD protein complex	SMAD2 SMAD3	6.70e-04	10	82	2	GO:0071141
GeneOntologyCellularComponent	polyprenyl diphosphate synthase complex	FNTB RABGGTA	9.78e-04	12	82	2	GO:0032476
MousePheno	decreased pruritus	MRGPRX1 MRGPRX3 MRGPRX4	2.47e-06	7	59	3	MP:0010073
MousePheno	abnormal pruritus	MRGPRX1 MRGPRX3 MRGPRX4	1.53e-05	12	59	3	MP:0010071
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	1.29e-16	49	81	11	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	3.32e-16	53	81	11	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	5.17e-16	55	81	11	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D24 TBC1D3F	5.17e-16	55	81	11	IPR000195
Domain	HSNSD	NDST3 NDST1 NDST4	3.13e-07	4	81	3	PF12062
Domain	Heparan_SO4_deacetylase	NDST3 NDST1 NDST4	3.13e-07	4	81	3	IPR021930
Domain	MRGPCRFAMILY	MRGPRX1 MRGPRX3 MRGPRX4	1.26e-05	11	81	3	IPR026234
Domain	TMEM183	TMEM183A TMEM183BP	1.86e-05	2	81	2	IPR026509
Domain	Sulfotransferase_dom	NDST3 NDST1 NDST4	5.06e-04	36	81	3	IPR000863
Domain	Sulfotransfer_1	NDST3 NDST1 NDST4	5.06e-04	36	81	3	PF00685
Domain	Dwarfin	SMAD2 SMAD3	5.11e-04	8	81	2	IPR013790
Domain	DWB	SMAD2 SMAD3	5.11e-04	8	81	2	SM00524
Domain	MH2	SMAD2 SMAD3	5.11e-04	8	81	2	PS51076
Domain	MH1	SMAD2 SMAD3	5.11e-04	8	81	2	PS51075
Domain	-	SMAD2 SMAD3	5.11e-04	8	81	2	3.90.520.10
Domain	MAD_homology_MH1	SMAD2 SMAD3	5.11e-04	8	81	2	IPR013019
Domain	MH2	SMAD2 SMAD3	5.11e-04	8	81	2	PF03166
Domain	SMAD_dom_Dwarfin-type	SMAD2 SMAD3	5.11e-04	8	81	2	IPR001132
Domain	Sp1_fam	SP6 SP7	8.17e-04	10	81	2	IPR030450
Domain	MBOAT_fam	PORCN SOAT2	9.96e-04	11	81	2	IPR004299
Domain	MBOAT	PORCN SOAT2	9.96e-04	11	81	2	PF03062
Domain	MAD_homology1_Dwarfin-type	SMAD2 SMAD3	1.19e-03	12	81	2	IPR003619
Domain	DWA	SMAD2 SMAD3	1.19e-03	12	81	2	SM00523
Domain	MH1	SMAD2 SMAD3	1.19e-03	12	81	2	PF03165
Domain	SMAD_dom-like	SMAD2 SMAD3	2.14e-03	16	81	2	IPR017855
Domain	-	SMAD2 SMAD3	2.14e-03	16	81	2	2.60.200.10
Domain	FA58C	CNTNAP5 EDIL3	3.70e-03	21	81	2	SM00231
Domain	FA58C_3	CNTNAP5 EDIL3	3.70e-03	21	81	2	PS50022
Domain	FA58C_1	CNTNAP5 EDIL3	3.70e-03	21	81	2	PS01285
Domain	FA58C_2	CNTNAP5 EDIL3	3.70e-03	21	81	2	PS01286
Domain	F-box_dom	TMEM183A TMEM183BP FBXO33	4.24e-03	75	81	3	IPR001810
Domain	F5_F8_type_C	CNTNAP5 EDIL3	4.82e-03	24	81	2	PF00754
Domain	FA58C	CNTNAP5 EDIL3	4.82e-03	24	81	2	IPR000421
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L LYZL6 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K	8.67e-12	99	59	10	M46448
Pathway	KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS	NDST3 NDST1 NDST4	1.12e-05	11	59	3	M47921
Pathway	REACTOME_SIGNALING_BY_NODAL	GDF1 SMAD2 SMAD3	1.16e-04	23	59	3	M511
Pathway	KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE	NDST3 NDST1 NDST4	1.69e-04	26	59	3	M7330
Pathway	REACTOME_HS_GAG_BIOSYNTHESIS	NDST3 NDST1 NDST4	2.36e-04	29	59	3	MM14802
Pathway	REACTOME_SIGNALING_BY_NODAL	SMAD2 SMAD3	2.56e-04	6	59	2	MM14517
Pathway	REACTOME_HS_GAG_BIOSYNTHESIS	NDST3 NDST1 NDST4	2.88e-04	31	59	3	M685
Pathway	REACTOME_LOSS_OF_FUNCTION_OF_SMAD2_3_IN_CANCER	SMAD2 SMAD3	3.57e-04	7	59	2	M29623
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES	SMAD2 SMAD3	3.57e-04	7	59	2	MM15661
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX_IN_CANCER	SMAD2 SMAD3	4.74e-04	8	59	2	M27246
Pathway	KEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY	SMAD2 SMAD3	4.74e-04	8	59	2	M47415
Pathway	KEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY	SMAD2 SMAD3	4.74e-04	8	59	2	M47849
Pathway	KEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY	SMAD2 SMAD3	4.74e-04	8	59	2	M47846
Pathway	WP_GLYCOSAMINOGLYCAN_SYNTHESIS_IN_FIBROBLASTS	NDST3 NDST1 NDST4	6.63e-04	41	59	3	M48095
Pathway	WP_TGFB_SMAD_SIGNALING	SMAD2 SMAD3	1.11e-03	12	59	2	M48091
Pathway	REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM	NDST3 NDST1 NDST4	1.48e-03	54	59	3	MM14633
Pathway	REACTOME_FORMATION_OF_AXIAL_MESODERM	SMAD2 SMAD3	1.52e-03	14	59	2	M46441
Pathway	REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM	NDST3 NDST1 NDST4	1.74e-03	57	59	3	M692
Pathway	REACTOME_SIGNALING_BY_ACTIVIN	SMAD2 SMAD3	1.75e-03	15	59	2	MM14593
Pathway	PID_SMAD2_3PATHWAY	SMAD2 SMAD3	1.99e-03	16	59	2	M228
Pathway	REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING	SMAD2 SMAD3	1.99e-03	16	59	2	MM14873
Pathway	REACTOME_GERM_LAYER_FORMATION_AT_GASTRULATION	SMAD2 SMAD3	2.25e-03	17	59	2	M45017
Pathway	WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING	SMAD2 SMAD3	2.25e-03	17	59	2	M39686
Pathway	BIOCARTA_TGFB_PATHWAY	SMAD2 SMAD3	2.25e-03	17	59	2	MM1509
Pathway	REACTOME_FORMATION_OF_DEFINITIVE_ENDODERM	SMAD2 SMAD3	2.25e-03	17	59	2	M48030
Pathway	REACTOME_SIGNALING_BY_ACTIVIN	SMAD2 SMAD3	2.25e-03	17	59	2	M26965
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES	SMAD2 SMAD3	2.25e-03	17	59	2	M27946
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.17e-30	11	83	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3G TBC1D3B TBC1D3F	5.39e-10	74	83	7	16625196
Pubmed	Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-08	3	83	3	28768771
Pubmed	The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-08	3	83	3	26022362
Pubmed	Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-08	3	83	3	27215903
Pubmed	Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-08	3	83	3	11850634
Pubmed	bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-08	3	83	3	10662793
Pubmed	Agonists of the MAS-related gene (Mrgs) orphan receptors as novel mediators of mast cell-sensory nerve interactions.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-08	3	83	3	18250432
Pubmed	Mas-related G protein-coupled receptor C11 (Mrgprc11) induces visceral hypersensitivity in the mouse colon: A novel target in gut nociception?	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-08	3	83	3	31119828
Pubmed	Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.	NDST3 NDST1 NDST4	5.23e-08	4	83	3	22049073
Pubmed	Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites.	NDST3 NDST1 NDST4	5.23e-08	4	83	3	12070138
Pubmed	MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	29064954
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	5.23e-08	4	83	3	12359748
Pubmed	Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	33727332
Pubmed	A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	10504302
Pubmed	A mechanically activated ion channel is functionally expressed in the MrgprB4 positive sensory neurons, which detect stroking of hairy skin in mice.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	28545921
Pubmed	Substance P activates Mas-related G protein-coupled receptors to induce itch.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	28219706
Pubmed	Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	35882236
Pubmed	Molecular Signature of Pruriceptive MrgprA3+ Neurons.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	32234460
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	5.23e-08	4	83	3	8406013
Pubmed	Overlap of direct and indirect alloreactive T-cell repertoires when MHC polymorphism is limited to the peptide binding groove.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	11821156
Pubmed	Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	17975009
Pubmed	Human sensory neuron-specific Mas-related G protein-coupled receptors-X1 sensitize and directly activate transient receptor potential cation channel V1 via distinct signaling pathways.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	23074220
Pubmed	Characterization of new G protein-coupled adenine receptors in mouse and hamster.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	23608776
Pubmed	The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	21775281
Pubmed	Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	26874069
Pubmed	Tick peptides evoke itch by activating MrgprC11/MRGPRX1 to sensitize TRPV1 in pruriceptors.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	33358893
Pubmed	USP48 alleviates bone cancer pain and regulates MrgC stabilization in spinal cord neurons of male mice.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	36864656
Pubmed	Low maternal care enhances the skin barrier resistance of offspring in mice.	MRGPRX1 MRGPRX3 MRGPRX4	5.23e-08	4	83	3	31295326
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	1.31e-07	5	83	3	12604796
Pubmed	Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-07	5	83	3	20004959
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	1.31e-07	5	83	3	8471161
Pubmed	Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-07	5	83	3	17618277
Pubmed	Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-07	5	83	3	20203048
Pubmed	Regional Differences in Itch Transmission.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-07	5	83	3	38735364
Pubmed	MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-07	5	83	3	34116733
Pubmed	Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-07	5	83	3	22472648
Pubmed	Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.	NDST3 NDST1 NDST4	1.31e-07	5	83	3	11087757
Pubmed	Cross-sensitization of histamine-independent itch in mouse primary sensory neurons.	MRGPRX1 MRGPRX3 MRGPRX4	1.31e-07	5	83	3	23000623
Pubmed	Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development.	NDST3 NDST1 NDST4 SMAD2	1.42e-07	20	83	4	17107998
Pubmed	A subpopulation of nociceptors specifically linked to itch.	MRGPRX1 MRGPRX3 MRGPRX4	2.61e-07	6	83	3	23263443
Pubmed	Visualizing the Itch-Sensing Skin Arbors.	MRGPRX1 MRGPRX3 MRGPRX4	2.61e-07	6	83	3	33091423
Pubmed	Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo.	MRGPRX1 MRGPRX3 MRGPRX4	2.61e-07	6	83	3	23364746
Pubmed	Identification of a bilirubin receptor that may mediate a component of cholestatic itch.	MRGPRX1 MRGPRX3 MRGPRX4	2.61e-07	6	83	3	30657454
Pubmed	Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.	MRGPRX1 MRGPRX3 MRGPRX4	2.61e-07	6	83	3	24549959
Pubmed	Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.	MRGPRX1 MRGPRX3 MRGPRX4	2.61e-07	6	83	3	26216096
Pubmed	MrgprC11+ sensory neurons mediate glabrous skin itch.	MRGPRX1 MRGPRX3 MRGPRX4	2.61e-07	6	83	3	33876765
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NDST1 TMEM129 FNTB CTC1 TMEM8B PIEZO1 GRK6 THAP8 NSD1 APEH TMEM187 ADGRA2 REPIN1 TBC1D24	3.38e-07	1105	83	14	35748872
Pubmed	Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity.	MRGPRX1 MRGPRX3 MRGPRX4	4.56e-07	7	83	3	36693373
Pubmed	FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling.	NDST3 NDST1 NDST4	7.28e-07	8	83	3	24067353
Pubmed	Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes.	MRGPRX1 MRGPRX3 MRGPRX4	7.28e-07	8	83	3	24583173
Pubmed	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.	MRGPRX1 MRGPRX3 MRGPRX4	7.28e-07	8	83	3	12909716
Pubmed	Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling.	MRGPRX1 MRGPRX3 MRGPRX4 SMAD2	9.03e-07	31	83	4	21300867
Pubmed	Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway.	MRGPRX1 MRGPRX3 MRGPRX4	1.09e-06	9	83	3	12397184
Pubmed	Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.	MRGPRX1 MRGPRX3 MRGPRX4	1.09e-06	9	83	3	30886406
Pubmed	Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens.	MRGPRX1 MRGPRX3 MRGPRX4	1.55e-06	10	83	3	33098765
Pubmed	A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.	MRGPRX1 MRGPRX3 MRGPRX4	2.13e-06	11	83	3	11551509
Pubmed	Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.	NDST3 NDST1 NDST4	2.13e-06	11	83	3	15944372
Pubmed	An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates.	MRGPRX1 MRGPRX3 MRGPRX4	2.13e-06	11	83	3	21151121
Pubmed	Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo.	GDF1 SMAD2 SMAD3	2.13e-06	11	83	3	23742838
Pubmed	Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.	NDST3 NDST1 NDST4	2.84e-06	12	83	3	12460940
Pubmed	Parallel ascending spinal pathways for affective touch and pain.	MRGPRX1 MRGPRX3 MRGPRX4	4.68e-06	14	83	3	33116307
Pubmed	Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification.	SMAD2 SMAD3	5.63e-06	2	83	2	26905010
Pubmed	Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.	SMAD2 SMAD3	5.63e-06	2	83	2	21496353
Pubmed	Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition.	SMAD2 SMAD3	5.63e-06	2	83	2	36050359
Pubmed	Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development.	SMAD2 SMAD3	5.63e-06	2	83	2	11984875
Pubmed	Reduction of Smad2 caused by oxidative stress leads to necrotic death of hypertrophic chondrocytes associated with an endemic osteoarthritis.	SMAD2 SMAD3	5.63e-06	2	83	2	33769459
Pubmed	Polycomb determines responses to smad2/3 signaling in embryonic stem cell differentiation and in reprogramming.	SMAD2 SMAD3	5.63e-06	2	83	2	23666711
Pubmed	Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.	SMAD2 SMAD3	5.63e-06	2	83	2	15665291
Pubmed	Inhibiting Smad2/3 signaling in pluripotent mouse embryonic stem cells enhances endoderm formation by increasing transcriptional priming of lineage-specifying target genes.	SMAD2 SMAD3	5.63e-06	2	83	2	27012147
Pubmed	Phosphorylated Smad2/3 immunoreactivity in sporadic and familial amyotrophic lateral sclerosis and its mouse model.	SMAD2 SMAD3	5.63e-06	2	83	2	18210139
Pubmed	Opposing roles for Smad2 and Smad3 in peritoneal fibrosis in vivo and in vitro.	SMAD2 SMAD3	5.63e-06	2	83	2	24925688
Pubmed	Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo.	SMAD2 SMAD3	5.63e-06	2	83	2	15520018
Pubmed	Nuclear exclusion of SMAD2/3 in granulosa cells is associated with primordial follicle activation in the mouse ovary.	SMAD2 SMAD3	5.63e-06	2	83	2	30111581
Pubmed	Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.	TMEM183A TMEM183BP	5.63e-06	2	83	2	16644869
Pubmed	The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.	SMAD2 SMAD3	5.63e-06	2	83	2	17074756
Pubmed	Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis.	SMAD2 SMAD3	5.63e-06	2	83	2	20010874
Pubmed	Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation.	SMAD2 SMAD3	5.63e-06	2	83	2	16382155
Pubmed	Molecular validation of the precision-cut kidney slice (PCKS) model of renal fibrosis through assessment of TGF-β1-induced Smad and p38/ERK signaling.	SMAD2 SMAD3	5.63e-06	2	83	2	26919280
Pubmed	Smad2 and Smad3 expressed in skeletal muscle promote immobilization-induced bone atrophy in mice.	SMAD2 SMAD3	5.63e-06	2	83	2	34710825
Pubmed	Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification.	EDIL3 SP7	5.63e-06	2	83	2	27134141
Pubmed	Evidence for a role of Smad3 and Smad2 in stabilization of the tumor-derived mutant Smad2.Q407R.	SMAD2 SMAD3	5.63e-06	2	83	2	12700238
Pubmed	Asthma-derived fibroblast to myofibroblast transition is enhanced in comparison to fibroblasts derived from non-asthmatic patients in 3D in vitro culture due to Smad2/3 signalling.	SMAD2 SMAD3	5.63e-06	2	83	2	33245228
Pubmed	Formation of the definitive endoderm in mouse is a Smad2-dependent process.	SMAD2 SMAD3	5.63e-06	2	83	2	10862745
Pubmed	Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes.	SMAD2 SMAD3	5.63e-06	2	83	2	24086574
Pubmed	Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo.	SMAD2 SMAD3	5.63e-06	2	83	2	28666967
Pubmed	The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach; particularly increasing in mucosae of Helicobacter-associated gastritis.	SMAD2 SMAD3	5.63e-06	2	83	2	21229365
Pubmed	Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation.	SMAD2 SMAD3	5.63e-06	2	83	2	22385658
Pubmed	Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile.	SMAD2 SMAD3	5.63e-06	2	83	2	15630024
Pubmed	Specific Smad2/3 Linker Phosphorylation Indicates Esophageal Non-neoplastic and Neoplastic Stem-Like Cells and Neoplastic Development.	SMAD2 SMAD3	5.63e-06	2	83	2	32705438
Pubmed	Smad2/3 Linker Phosphorylation Is a Possible Marker of Pancreatic Stem/Progenitor Cells in the Regenerative Phase of Acute Pancreatitis.	SMAD2 SMAD3	5.63e-06	2	83	2	28099259
Pubmed	Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell Differentiation.	SMAD2 SMAD3	5.63e-06	2	83	2	26354774
Pubmed	Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium.	SMAD2 SMAD3	5.63e-06	2	83	2	35780861
Pubmed	Role of SMPD3 during Bone Fracture Healing and Regulation of Its Expression.	SMPD3 SP7	5.63e-06	2	83	2	30530524
Pubmed	Implication of Smad2 and Smad3 in transforming growth factor-β-induced posterior capsular opacification of human lens epithelial cells.	SMAD2 SMAD3	5.63e-06	2	83	2	24911914
Pubmed	Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.	SMAD2 SMAD3	5.63e-06	2	83	2	29174331
Pubmed	Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells.	SMAD2 SMAD3	5.63e-06	2	83	2	19172185
Pubmed	The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling.	SMAD2 SMAD3	5.63e-06	2	83	2	11937490
Pubmed	The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice.	SMAD2 SMAD3	5.63e-06	2	83	2	15133179
Pubmed	Cocaine increases quantal norepinephrine secretion through NET-dependent PKC activation in locus coeruleus neurons.	SLC6A2 EDIL3	5.63e-06	2	83	2	35977516
Interaction	NDST4 interactions	NDST3 NDST1 NDST4	3.20e-06	8	79	3	int:NDST4
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LYZL6 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	6.91e-17	149	83	12	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	1.07e-06	99	83	5	17q12
Cytoband	11p15.1	MRGPRX1 MRGPRX3 MRGPRX4	1.81e-04	60	83	3	11p15.1
Cytoband	5q35	GRK6 NSD1	7.97e-04	23	83	2	5q35
GeneFamily	Sulfotransferases, membrane bound	NDST3 NDST1 NDST4	1.06e-04	37	45	3	763
GeneFamily	SMAD family	SMAD2 SMAD3	1.68e-04	8	45	2	750
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP6 SP7	2.16e-04	9	45	2	755
GeneFamily	G protein-coupled receptors, Class A orphans	MRGPRX1 MRGPRX3 MRGPRX4	9.62e-04	78	45	3	262
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	4.73e-11	90	79	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	COL4A2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D PORCN GDF1 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.32e-09	320	79	12	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PORCN TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	6.58e-09	213	79	10	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PORCN TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	6.58e-09	213	79	10	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	EPHX2 ABHD15 TBC1D3 TBC1D3H TBC1D3L TBC1D3D AVPR1A TMEM8B ACSS2 LY75 EDIL3 TBC1D3G ADGRA2 TBC1D3C TBC1D3B SOAT2 SMAD3 TBC1D3K TBC1D3F	6.80e-09	1049	79	19	PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.88e-07	242	79	9	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.00e-06	281	79	9	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.00e-06	281	79	9	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	EPHX2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TMEM8B WFIKKN1 GDF1 TBC1D3G TBC1D3C TBC1D3B SMAD3 TBC1D3K TBC1D3F	3.81e-05	1075	79	14	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	COL4A2 EPHX2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TMEM8B WFIKKN1 TMEM44 GDF1 TBC1D3G TBC1D3C TBC1D3B SMAD3 TBC1D3K TBC1D3F	8.33e-05	1466	79	16	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD15 MAP1A TMEM8B SMPD3 REPIN1 FAM221B	1.18e-06	182	83	6	9bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD15 MAP1A TMEM8B SMPD3 TBC1D3B FAM221B	1.18e-06	182	83	6	02c0824373a0ecebc922d4ca848ace9d570722c4
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD15 MAP1A TMEM8B SMPD3 REPIN1 FAM221B	1.18e-06	182	83	6	4602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell	(02)_MMP9/10+-(1)_GFP\|(02)_MMP9/10+ / shred by cell type by condition	SLC6A2 COL4A2 PIEZO1 MUC5B MMP10 VARS1	1.97e-06	199	83	6	448ba982be804007f991d469eca9d885b21ae499
ToppCell	LAM-Lymphoid-pDC\|LAM / Condition, Lineage and Cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	1.28e-05	161	83	5	bb5b44713e4da4406cdaa79dcf2aa9f97e3cf75a
ToppCell	(3)_MNP-(3)_DC_plasmacytoid\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABHD15 MAP1A TMEM8B SMPD3 SP7	1.57e-05	168	83	5	13c160ea1a19b47d2e7e2dae818c8dcde4e3e377
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EPHX2 FNDC9 MYO18B EDIL3 REPIN1	1.61e-05	169	83	5	44d201361eb497222a4972a0e10bac1e05dcfd0a
ToppCell	severe_influenza-pDC\|World / disease group, cell group and cell class (v2)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	1.66e-05	170	83	5	b9c08af83241666bbdbed9109cadcd088c0f647d
ToppCell	ICU-SEP-Myeloid-pDC\|ICU-SEP / Disease, Lineage and Cell Type	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	1.71e-05	171	83	5	72c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell	metastatic_Lymph_Node-Myeloid_cells-pDCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	1.71e-05	171	83	5	1f8e66073088fc1969782e443bf00f8c1877ea91
ToppCell	severe_influenza-pDC\|severe_influenza / disease group, cell group and cell class (v2)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	1.86e-05	174	83	5	d8d2ded5812ed3b3db4109585714a6513c13326a
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABHD15 MAP1A SMPD3 REPIN1 FAM221B	1.91e-05	175	83	5	97fe431f224b592b3076632d101e19136c138dcc
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	ABHD15 MAP1A TMEM8B THAP8 SMPD3	1.91e-05	175	83	5	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	ABHD15 MAP1A TMEM8B THAP8 SMPD3	1.96e-05	176	83	5	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-pDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.02e-05	177	83	5	e36c2005be74ee8ff03c2052504cb496faf86009
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A2 AVPR1A STEAP4 GPNMB SOAT2	2.13e-05	179	83	5	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	tumor_Lung-Myeloid_cells-pDCs\|tumor_Lung / Location, Cell class and cell subclass	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.25e-05	181	83	5	c864ffeb9234b8c29754afc91c85a972889617f4
ToppCell	metastatic_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.31e-05	182	83	5	02e04294fce12591c32d7bd0e866a000ad1f836e
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.37e-05	183	83	5	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|normal_Lung / Location, Cell class and cell subclass	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.37e-05	183	83	5	c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell	URO-Myeloid-pDC\|URO / Disease, Lineage and Cell Type	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.43e-05	184	83	5	0edb5dd003c2bca0b9e3ec18d03610d68bd52538
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.49e-05	185	83	5	cc5152d3055375172bdf84f442b233c8fbd422b3
ToppCell	Healthy_donor-pDC\|Healthy_donor / disease group, cell group and cell class (v2)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.49e-05	185	83	5	7fbb55cbdb39bdecb6063c8ba9776ab06c2666e8
ToppCell	ICU-NoSEP-Myeloid-pDC\|ICU-NoSEP / Disease, Lineage and Cell Type	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.49e-05	185	83	5	7564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	b70cd94c651b56dcf2e55554533a5f1130845390
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	31df1eafa3010bc1be6fc4d4689f1393d69b6b13
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	eaa431ccd4cdd36fe06a44987603ec9979025aa8
ToppCell	tumor_Lung-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	3d7c1a281fb82db4471283f39937007d889a5f38
ToppCell	COVID-19_Severe-Myeloid-pDC\|COVID-19_Severe / Disease group, lineage and cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	3db5ed69d49e5d79f990aca0295ddce4c297a05c
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	b95be984e308d4f9061274a35995ec558d434e74
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	8f7949740286f64e034d1eb533ebc2c6f71ae966
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.56e-05	186	83	5	95c7318e521fb6aa02e244b1e81e6b2a62107756
ToppCell	Healthy_donor-pDC\|World / disease group, cell group and cell class (v2)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.62e-05	187	83	5	aa2cc54487d3c5045ac0c93560944c5a55878e27
ToppCell	LAM-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.62e-05	187	83	5	4d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.69e-05	188	83	5	de6a270b6e4fe09c39a52c296632d86ada98465b
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.69e-05	188	83	5	89411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.69e-05	188	83	5	879054b780378ae05be68e597c77c931bf0ade03
ToppCell	myeloid-pDC\|myeloid / Lineage and Cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.69e-05	188	83	5	a2dc4bbeca2bdc00c51825dd65a699c54c72f241
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.76e-05	189	83	5	209cae68d78c8f72479b169e27c3ff7e143adece
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.76e-05	189	83	5	a9ad1fb12304541f909dd0eeac9b9eb28c31fd41
ToppCell	COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease group, lineage and cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.76e-05	189	83	5	c6cfd6aa21c19f2c62d80218bbc924e14e82aada
ToppCell	Control-Myeloid-pDC\|Control / Disease group, lineage and cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.76e-05	189	83	5	46770b99da42f11f10cfc67cea8562342d60b867
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.76e-05	189	83	5	98ca646231fbd5f29827c2dd31ac4503026bad7d
ToppCell	PBMC-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	adffa93635da10251f28b2089fd96b189775c8b4
ToppCell	BLOOD--(3)_MNP-(3)_DC_(cDC+pDC)\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ABHD15 MAP1A TMEM8B SMPD3 REPIN1	2.83e-05	190	83	5	9b8de47f7a2e6137d934ccce32417ab15eb54f46
ToppCell	PBMC-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	9a91bf1ea105029e6412d0d9060bca325299ce26
ToppCell	(0)_Myeloid-(01)_Dendritic_cell\|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)	SLC6A2 MAP1A SMPD3 REPIN1 FAM221B	2.83e-05	190	83	5	e9507bb0c8ff3d071402731a9b8cfe1bba93fab0
ToppCell	MS-pDC\|MS / Condition, Cell_class and T cell subcluster	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	f41d7ab7d7fbcd73fddb6c3533c6a3e642e3d07f
ToppCell	PBMC-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	39c8ddc2639bf3e986dae11fbae61a735614b604
ToppCell	PBMC-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	a95aea3aa707fc4574810706341a5f32b3d00209
ToppCell	PBMC-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	18dfa84c62dcf081ce9958a71e76a394ec0968e4
ToppCell	COVID-19_Severe-pDC\|COVID-19_Severe / disease group, cell group and cell class	ABHD15 MAP1A TMEM8B SMPD3 REPIN1	2.83e-05	190	83	5	c5ab6b7492fb86aff3d2af3eb671c9f985ae4aeb
ToppCell	MS-pDC-\|MS / Condition, Cell_class and T cell subcluster	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	f56ec302d556ace4f7609017a35c311cf43aa8a5
ToppCell	PBMC-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.83e-05	190	83	5	2c1c079fd411c03bc3f383aa927eea9446716960
ToppCell	COVID-19_Moderate-pDC\|World / disease group, cell group and cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.90e-05	191	83	5	93adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCell	(011)_pDC\|World / immune cells in Peripheral Blood (logTPM normalization)	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.90e-05	191	83	5	d82ac4f6d9863734e09bf3cb71c1354a49b66b4f
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.90e-05	191	83	5	8c487704cbbb5eeff54e8c6fb6fffa1472b5351f
ToppCell	Healthy-pDC\|World / disease group, cell group and cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.90e-05	191	83	5	6e1d825dc33b915b95f13ccd237a552160a4be98
ToppCell	COVID-19_Moderate-pDC\|COVID-19_Moderate / disease group, cell group and cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.90e-05	191	83	5	9d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.90e-05	191	83	5	78d523f562d32fc408a20d99b0c61cc103241bc0
ToppCell	Healthy-pDC\|Healthy / disease group, cell group and cell class	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	2.98e-05	192	83	5	33d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCell	normal-na-Myeloid-plasmacytoid_dendritic_cell-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	3.13e-05	194	83	5	74545942aded51a0f4ee96054b4ce12c4d99a8a0
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	3.13e-05	194	83	5	3f9e4a8e5699bc379e8a0d337e0daef09632e71c
ToppCell	normal-na-Myeloid-plasmacytoid_dendritic_cell\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	3.13e-05	194	83	5	c25fc353001cdf9fcd772da5a254c857e555eab8
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	3.13e-05	194	83	5	5250736b608001fb73aa74dee8cb8465a1d2f372
ToppCell	Biopsy_Other_PF-Immune-pDCs\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ABHD15 MAP1A TMEM8B SMPD3 FAM221B	3.37e-05	197	83	5	598a130eb7afb1bb95da64a964218362627feb49
ToppCell	COVID-19-COVID-19_Severe-Myeloid-pDC\|COVID-19_Severe / Disease, condition lineage and cell class	ABHD15 MAP1A TMEM8B SMPD3 REPIN1	3.45e-05	198	83	5	033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCell	COVID-19-COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease, condition lineage and cell class	ABHD15 MAP1A TMEM8B SMPD3 REPIN1	3.53e-05	199	83	5	9de61e5189d907cc969ac3043d68204f70acc0bf
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_smooth_muscle-like\|E16.5-samps / Age Group, Lineage, Cell class and subclass	AVPR1A TMEM151B NDST4 FAM221B	1.09e-04	132	83	4	9633653dba1edee47d915212fb6e68426da49de5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HCAR2 MOGAT1 THAP8 SMAD3	2.17e-04	158	83	4	1635a85fc73c544028418087f36d28957dd4f458
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ABHD15 MOGAT1 MAP1A SMPD3	2.17e-04	158	83	4	2af7beb48272e5368d9ba6b80f08d47ab8556c08
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HCAR2 MOGAT1 THAP8 SMAD3	2.17e-04	158	83	4	80841dadfa53bcde36a3e486408a095f78e772eb
ToppCell	367C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ABHD15 MAP1A TMEM8B SMPD3	2.50e-04	164	83	4	95b800c78871354c859abaa832d778786ef7bcc0
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD15 GALR3 WFIKKN1 ADGRA2	2.50e-04	164	83	4	b895674ed2df87db8fbfb30b7e31620945588491
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HCAR2 CNTNAP5 STEAP4 MUC5B	2.62e-04	166	83	4	9e98e6070055bfc780becee52d77830e06b6d854
ToppCell	367C-Myeloid-Dendritic-pDC\|367C / Donor, Lineage, Cell class and subclass (all cells)	ABHD15 MAP1A TMEM8B SMPD3	2.68e-04	167	83	4	650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell	control-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAP1A PORCN SMPD3 FAM221B	2.74e-04	168	83	4	affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCell	(3)_DC_plasmacytoid\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABHD15 MAP1A TMEM8B SMPD3	2.74e-04	168	83	4	8a913db9b2a1a4ff96fb139734a3834e6aa263f1
ToppCell	367C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	ABHD15 MAP1A TMEM8B SMPD3	2.87e-04	170	83	4	fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	MAP1A TMEM8B SMPD3 FAM221B	2.87e-04	170	83	4	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	EPHX2 FNDC9 MYO18B EDIL3	2.87e-04	170	83	4	513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell	COVID-pDC\|COVID / Condition, Cell_class and T cell subcluster	MAP1A TMEM8B SMPD3 FAM221B	3.00e-04	172	83	4	3ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HCAR2 TBC1D3 MOGAT1 GPNMB	3.00e-04	172	83	4	c8ea80042faf923b08ff03d73100533d521d73ef
ToppCell	COVID-pDC-\|COVID / Condition, Cell_class and T cell subcluster	MAP1A TMEM8B SMPD3 FAM221B	3.00e-04	172	83	4	a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	STEAP4 MUC5B MMP10 TBC1D3G	3.06e-04	173	83	4	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	facs-Marrow-T_cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	YIPF2 PDIA6 AVPR1A GPNMB	3.06e-04	173	83	4	e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABHD15 HCAR2 TMEM8B WFIKKN1	3.13e-04	174	83	4	009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCell	IIF-Myeloid-pDC\|IIF / Disease, Lineage and Cell Type	ABHD15 MAP1A TMEM8B SMPD3	3.20e-04	175	83	4	35cfb7d0b88678ff5b83ad6e19dbc15a908a3fcc
ToppCell	facs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	YIPF2 PDIA6 AVPR1A GPNMB	3.20e-04	175	83	4	4be01bf30331162f1998216fb2871a4e626dc440
ToppCell	IPF-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ABHD15 MAP1A CTC1 SMPD3	3.20e-04	175	83	4	a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell	ILEUM-inflamed-(3)_pDC\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAP1A TMEM8B SMPD3 FAM221B	3.27e-04	176	83	4	b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell	Control-Myeloid-pDC\|Control / Disease state, Lineage and Cell class	ABHD15 MAP1A CTC1 SMPD3	3.34e-04	177	83	4	3940663bb5b45b2ca9f772550380a516c53e410b
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABHD15 MAP1A TMEM8B SMPD3	3.34e-04	177	83	4	507f06d31ab773099c9431b6f433899dc97b5566
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABHD15 MAP1A TMEM8B SMPD3	3.34e-04	177	83	4	8887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TBC1D3L MYO18B LY75 REPIN1	3.34e-04	177	83	4	a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCell	Healthy/Control-pDC\|Healthy/Control / Disease group and Cell class	MAP1A TMEM8B SMPD3 FAM221B	3.41e-04	178	83	4	072b346c6bbd63f00efaceda486400a669b3ec48
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD15 GALR3 MYO18B TBC1D3B	3.41e-04	178	83	4	0b59e3d75b143bd7bf91a7800a49699c51e68c5a
ToppCell	IPF-Myeloid-pDC\|IPF / Disease state, Lineage and Cell class	ABHD15 MAP1A CTC1 SMPD3	3.41e-04	178	83	4	8d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell	Control-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ABHD15 MAP1A CTC1 SMPD3	3.41e-04	178	83	4	20ef63d925e67ddd5955832312ca8574a6f838a4
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABHD15 MOGAT1 MAP1A SMPD3	3.48e-04	179	83	4	124da6f882968dc0d05f3edd8f3b4d61617cc214
Disease	autism spectrum disorder (implicated_via_orthology)	SLC6A2 NDST3 NDST1 CNTNAP5 NDST4	3.36e-05	152	71	5	DOID:0060041 (implicated_via_orthology)
Disease	superoxide dismutase [Mn]; mitochondrial measurement	GRK6 NSD1	3.41e-05	4	71	2	EFO_0021981
Disease	azoospermia (implicated_via_orthology)	NDST3 NDST1 NDST4	3.75e-05	27	71	3	DOID:14227 (implicated_via_orthology)
Disease	Loeys-Dietz Syndrome	SMAD2 SMAD3	1.19e-04	7	71	2	C2697932
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP5 CRBN	1.58e-04	8	71	2	DOID:0060308 (implicated_via_orthology)
Disease	repulsive guidance molecule A measurement	TMEM8B FAM221B	2.03e-04	9	71	2	EFO_0008273
Disease	transmembrane glycoprotein NMB measurement	GRK6 GPNMB	2.54e-04	10	71	2	EFO_0008303
Disease	intellectual disability (implicated_via_orthology)	NDST3 NDST1 NDST4	7.96e-04	75	71	3	DOID:1059 (implicated_via_orthology)
Disease	apolipoprotein A 1 measurement	MOGAT1 MAP1A SP6 NSD1 SPG11 SMPD3 RABGGTA SP7	9.69e-04	848	71	8	EFO_0004614
Disease	acetate measurement	SPG11 ACSS2	1.05e-03	20	71	2	EFO_0010112
Disease	CCL4 measurement	TBC1D3 TBC1D3F	1.05e-03	20	71	2	EFO_0004751
Disease	Autism Spectrum Disorders	EPHX2 AVPR1A MTNR1B	1.14e-03	85	71	3	C1510586
Disease	Left Ventricle Remodeling	SMAD2 SMAD3	1.16e-03	21	71	2	C0600520
Disease	Ventricular Remodeling	SMAD2 SMAD3	1.16e-03	21	71	2	C0600519
Disease	left atrial function	MOGAT1 MYO18B	1.16e-03	21	71	2	EFO_0004294
Disease	aspartate measurement	NDST3 GRK6	1.52e-03	24	71	2	EFO_0010462
Disease	Lynch syndrome (is_implicated_in)	SMAD2 SMAD3	1.52e-03	24	71	2	DOID:3883 (is_implicated_in)
Disease	upper respiratory tract disorder	FBXO33 SMAD3	2.07e-03	28	71	2	MONDO_0004867
Disease	lumbar disc degeneration	CRBN SMAD3	2.07e-03	28	71	2	EFO_0004994

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSWLGHLFLFPRWSY	CTC1	151	Q2NKJ3
RDHSPYCWLVWRPSL	ADGRA2	911	Q96PE1
PGWRRWNFIYVFHTL	GPNMB	166	Q14956
DLPWFRTLSWYFLLC	CDS2	121	O95674
HCPAGWRSLWIGYSF	COL4A2	1611	P08572
KFHCANLTSWPRWLY	CRBN	231	Q96SW2
AWLWYHRVVGAQRCP	ACSS2	446	Q9NR19
LRCREWFEAGLPWPY	ABHD15	266	Q6UXT9
EVCRWSSWYNGHRPE	MUC5B	1336	Q9HC84
RCLVPGWYASHIERW	NDST3	741	O95803
RYRWWPAEICHPRAV	NSD1	1766	Q96L73
YAHWGPRWAFSLVCG	MFSD8	476	Q8NHS3
RYFWRRSHWNPEPEF	MMP10	311	P09238
FTSYLHVLPLWFWCP	MOGAT1	136	Q96PD6
HVLPLWFWCPVFREY	MOGAT1	141	Q96PD6
MRCREWYGWHFPELG	NOP58	181	Q9Y2X3
YWRELSCERKVWFPH	MAP1A	1696	P78559
WVEWRLHCSGRPLFY	LYZL6	126	O75951
NYVRRWDWKFGDIPC	HCAR2	86	Q8TDS4
WCVRCHEPRWSYRAG	FNDC9	136	Q8TBE3
WHRWVIAPRGFLANY	GDF1	281	P27539
IYRRWHTPLHICLIW	MTNR1B	151	P49286
SHWRECLFYPALWPQ	FBXO33	96	Q7Z6M2
IGWRCPHYLWDCFRI	FAM221B	251	A6H8Z2
CLVPGWYATHIERWL	NDST1	751	P52848
KVFHRPWRRGWHFYD	LY75	756	O60449
PWRRGWHFYDDREFI	LY75	761	O60449
RHLELWVGYYIRWNP	MTMR2	571	Q13614
WPIWYHCRRPRYLSS	MRGPRX3	126	Q96LB0
CLVPGWYAVHIERWL	NDST4	741	Q9H3R1
WALIFPCYWLVDRLA	SMPD3	21	Q9NY59
VWPAWVYCTRYSDRP	EN1	271	Q05925
SHWVTFGCWIFYRLI	PORCN	446	Q9H237
GVSYWRVPHELIECW	KCTD18	221	Q6PI47
LCWGPHHALILCFWY	GALR3	246	O60755
IYARHIRILPWSWYG	EDIL3	451	O43854
VCLCHGFPESWYSWR	EPHX2	261	P34913
LDASRPWLCYWILHS	FNTB	96	P49356
RWLLTAAHCRKPYLW	KLK9	56	Q9UKQ9
QFRDYCAICLRWEWP	FHIP2A	601	Q5W0V3
RYTFSPDWWALGCLL	GRK6	361	P43250
WRIGPLRCYGDRRFW	CNTNAP5	776	Q8WYK1
WLVEFYAPWCGHCQR	PDIA6	46	Q15084
LWQHDEPCYWRLTRV	MRPS34	86	P82930
ISRQLWWGHRIPAYF	VARS1	721	P26640
FRPGLYWRLCWKFVS	SLC6A2	511	P23975
HFTPSCFQWRWGVRY	THAP8	61	Q8NA92
CFQWRWGVRYLRPDA	THAP8	66	Q8NA92
PCIWWKAISYHYVRR	TMEM151B	161	Q8IW70
RLFDWWHPQYPFSLR	TMEM183BP	361	Q1AE95
SYGTWHHRCWLLGRL	RABGGTA	106	Q92696
HPAYWRFWLCVSVVY	PTDSS2	121	Q9BVG9
RWHSGDRPFVCNWLF	SP6	276	Q3SY56
WPIWYRCHRPTHLSA	MRGPRX1	126	Q96LB2
GPWFRHYDFRQSCWV	TBC1D3L	466	B9A6J9
WPIWYRCRRPTHLSA	MRGPRX4	126	Q96LA9
FPGWVALWLHTRRCQ	REPIN1	66	Q9BWE0
WYARRHCPLPQATFW	SOAT2	496	O75908
VGWWHEPFRLGIRFC	APEH	261	P13798
WPHLYGTADRCWLHL	ADGRE3	486	Q9BY15
GRCCLEGPFWHFLWE	SPG11	76	Q96JI7
DWQRWLFGELPLCYF	TBC1D24	211	Q9ULP9
GPWFRHYDFRQSCWV	TBC1D3B	466	A6NDS4
GPWFRHYDFRQSCWV	TBC1D3H	466	P0C7X1
RLFDWWHPQYPFSLR	TMEM183A	361	Q8IXX5
GPWFRHYDFRQSCWV	TBC1D3F	466	A6NER0
RWHTGERPFVCNWLF	SP7	316	Q8TDD2
VIYCRLWRWPDLHSH	SMAD2	126	Q15796
VIYCRLWRWPDLHSH	SMAD3	86	P84022
YRRFPDWLDHWMLCR	STEAP4	276	Q687X5
LWDWDYLDRCFARHR	TMEM44	11	Q2T9K0
GPWFRHYDFRQSCWV	TBC1D3E	466	A0A087X179
WRRWLFYLCPGSLIA	TMEM8B	376	A6NDV4
WDITYRFRGPDWLCR	AVPR1A	111	P37288
WDPVRYDLTGWLHRA	MYO18B	1091	Q8IUG5
WEPRWAYSPLLQQCH	WFIKKN1	371	Q96NZ8
PIFAWPVAWCLYLDR	TMEM187	121	Q14656
GPWFRHYDFRQSCWV	TBC1D3D	466	A0A087WVF3
PALCIDYPWRWSRAV	PIEZO1	1061	Q92508
IYYWSRDRWACHPLA	TMEM129	111	A0AVI4
CYAWLVPLALWGFLR	YIPF2	171	Q9BWQ6
GPWFRHYDFRQSCWV	TBC1D3G	466	Q6DHY5
GPWFRHYDFRQSCWV	TBC1D3	466	Q8IZP1
GPWFRHYDFRQSCWV	TBC1D3K	466	A0A087X1G2
GPWFRHYDFRQSCWV	TBC1D3I	466	A0A087WXS9
GPWFRHYDFRQSCWV	TBC1D3C	466	Q6IPX1