Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-25 ERVK-9	1.51e-09	37	62	6	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-25 ERVK-9	1.79e-09	38	62	6	GO:0070001
GeneOntologyMolecularFunction	structural molecule activity	COL4A3 ERVK-6 TINAG SPTBN2 ERVK-8 ERVK-19 ERVK-21 ERVK-25 ERVK-9 CLDN23 ADD2	8.28e-05	891	62	11	GO:0005198
GeneOntologyMolecularFunction	splicing factor binding	SF3B1 RBM20	1.97e-04	7	62	2	GO:1990935
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-6 ZFHX4 CYP51A1 ERVK-8 ERVK-19 ZFHX3 ERVK-21 ERVK-9 NBR1 ALOX12 RBM20 ZMYM4	2.54e-04	1189	62	12	GO:0046914
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	RHOXF2B FOXP4 ZNF526 KMT2D HIVEP2 ZFHX4 RHOXF2 MAZ NFYA GBX2 FOXP1 ZFHX3 CREB5	3.32e-04	1412	62	13	GO:0000981
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 TINAG ERVK-8 ERVK-19 ERVK-21 ERVK-25 ERVK-9	3.62e-04	430	62	7	GO:0004175
GeneOntologyMolecularFunction	zinc ion binding	ERVK-6 ZFHX4 ERVK-8 ERVK-19 ZFHX3 ERVK-21 ERVK-9 NBR1 RBM20 ZMYM4	3.88e-04	891	62	10	GO:0008270
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	RHOXF2B FOXP4 ZNF526 HIVEP2 ZFHX4 RHOXF2 MAZ NFYA GBX2 FOXP1 ZFHX3 MED12 CREB5	4.55e-04	1459	62	13	GO:0000977
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-8	5.12e-04	11	62	2	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-8	8.43e-04	14	62	2	GO:0003964
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 TINAG ERVK-8 ERVK-19 ERVK-21 ERVK-25 ERVK-9 LACTB	9.02e-04	654	62	8	GO:0008233
GeneOntologyMolecularFunction	transcription coregulator activity	NRG1 KMT2D TCF20 BCL9 KAT6B HDAC7 MED12	1.74e-03	562	62	7	GO:0003712
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-8	1.92e-03	21	62	2	GO:0035613
GeneOntologyMolecularFunction	chromatin binding	SF3B1 MAZ AUTS2 FOXP1 MBD5 KAT6B HDAC7 MED12	1.96e-03	739	62	8	GO:0003682
GeneOntologyMolecularFunction	transcription coactivator activity	KMT2D TCF20 BCL9 KAT6B MED12	2.49e-03	303	62	5	GO:0003713
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	5.68e-06	85	62	5	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	5.68e-06	85	62	5	GO:0000768
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	7.12e-06	89	62	5	GO:0006949
GeneOntologyBiologicalProcess	negative regulation of lung goblet cell differentiation	FOXP4 FOXP1	8.89e-06	2	62	2	GO:1901250
GeneOntologyBiologicalProcess	regulation of lung goblet cell differentiation	FOXP4 FOXP1	2.66e-05	3	62	2	GO:1901249
GeneOntologyBiologicalProcess	innate vocalization behavior	AUTS2 FOXP1	2.66e-05	3	62	2	GO:0098582
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	KMT2D HIVEP2 SF3B1 TCF20 MAZ NFYA AUTS2 GBX2 FOXP1 ZFHX3 BCL9 KAT6B MED12 CREB5	5.08e-05	1390	62	14	GO:0045944
GeneOntologyBiologicalProcess	lung goblet cell differentiation	FOXP4 FOXP1	1.32e-04	6	62	2	GO:0060480
GeneOntologyBiologicalProcess	lobar bronchus epithelium development	FOXP4 FOXP1	1.85e-04	7	62	2	GO:0060481
GeneOntologyBiologicalProcess	lobar bronchus development	FOXP4 FOXP1	2.46e-04	8	62	2	GO:0060482
GeneOntologyBiologicalProcess	regulation of endothelial tube morphogenesis	FOXP1 ALOX12	2.46e-04	8	62	2	GO:1901509
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	COL4A3 ERVK-6 SF3B1 ATXN2 ERVK-8 GBX2 ERVK-19 ERVK-21 ERVK-9 HDAC7 RBM20 MED12 SPEM1	3.90e-04	1483	62	13	GO:0048646
Domain	FOXP-CC	FOXP4 FOXP1	5.28e-05	4	56	2	PF16159
Domain	FOXP-CC	FOXP4 FOXP1	5.28e-05	4	56	2	IPR032354
Domain	ZnF_U1	ZFHX4 ZFHX3 RBM20	8.83e-05	29	56	3	SM00451
Domain	Znf_U1	ZFHX4 ZFHX3 RBM20	8.83e-05	29	56	3	IPR003604
Domain	Homeobox_CS	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	2.35e-04	186	56	5	IPR017970
Domain	Homeobox	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	6.72e-04	234	56	5	PF00046
Domain	HOMEOBOX_1	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	6.98e-04	236	56	5	PS00027
Domain	HOX	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	7.11e-04	237	56	5	SM00389
Domain	HOMEOBOX_2	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	7.39e-04	239	56	5	PS50071
Domain	Homeobox_dom	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	7.39e-04	239	56	5	IPR001356
Domain	PB1	PRKCI NBR1	7.85e-04	14	56	2	SM00666
Domain	PB1	PRKCI NBR1	7.85e-04	14	56	2	PF00564
Domain	PB1	PRKCI NBR1	7.85e-04	14	56	2	PS51745
Domain	PB1_dom	PRKCI NBR1	7.85e-04	14	56	2	IPR000270
Domain	Znf_FYVE_PHD	KMT2D TCF20 FGD5 KAT6B	9.85e-04	147	56	4	IPR011011
Domain	-	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	1.57e-03	283	56	5	1.10.10.60
Domain	EPHD	KMT2D TCF20	1.96e-03	22	56	2	PS51805
Domain	ZINC_FINGER_C2H2_2	FOXP4 ZNF526 HIVEP2 ZFHX4 MAZ FOXP1 ZFHX3 CREB5	2.06e-03	775	56	8	PS50157
Domain	ZINC_FINGER_C2H2_1	FOXP4 ZNF526 HIVEP2 ZFHX4 MAZ FOXP1 ZFHX3 CREB5	2.10e-03	777	56	8	PS00028
Domain	PHD	KMT2D TCF20 KAT6B	2.42e-03	89	56	3	SM00249
Domain	Znf_C2H2-like	FOXP4 ZNF526 HIVEP2 ZFHX4 MAZ FOXP1 ZFHX3 CREB5	2.44e-03	796	56	8	IPR015880
Domain	Znf_PHD	KMT2D TCF20 KAT6B	2.57e-03	91	56	3	IPR001965
Domain	Znf_C2H2	FOXP4 ZNF526 HIVEP2 ZFHX4 MAZ FOXP1 ZFHX3 CREB5	2.61e-03	805	56	8	IPR007087
Domain	ZnF_C2H2	FOXP4 ZNF526 HIVEP2 ZFHX4 MAZ FOXP1 ZFHX3 CREB5	2.67e-03	808	56	8	SM00355
Domain	ZF_PHD_2	KMT2D TCF20 KAT6B	2.91e-03	95	56	3	PS50016
Domain	ZF_PHD_1	KMT2D TCF20 KAT6B	3.00e-03	96	56	3	PS01359
Domain	Homeodomain-like	RHOXF2B ZFHX4 RHOXF2 GBX2 ZFHX3	3.13e-03	332	56	5	IPR009057
Domain	TF_fork_head_CS_2	FOXP4 FOXP1	8.40e-03	46	56	2	IPR030456
Domain	TF_fork_head_CS_1	FOXP4 FOXP1	8.75e-03	47	56	2	IPR018122
Domain	FH	FOXP4 FOXP1	9.49e-03	49	56	2	SM00339
Domain	FORK_HEAD_1	FOXP4 FOXP1	9.49e-03	49	56	2	PS00657
Domain	FORK_HEAD_2	FOXP4 FOXP1	9.49e-03	49	56	2	PS00658
Domain	Fork_head_dom	FOXP4 FOXP1	9.49e-03	49	56	2	IPR001766
Domain	FORK_HEAD_3	FOXP4 FOXP1	9.49e-03	49	56	2	PS50039
Domain	Forkhead	FOXP4 FOXP1	9.49e-03	49	56	2	PF00250
Domain	-	RNF214 KMT2D RNF44 FGD5 KAT6B	1.10e-02	449	56	5	3.30.40.10
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	1.41e-11	12	64	5	14557543
Pubmed	Interaction network of human early embryonic transcription factors.	FOXP4 KMT2D HIVEP2 TCF20 ZFHX4 AUTS2 FOXP1 ZFHX3 BCL9 MED12 ZMYM4	4.37e-11	351	64	11	38297188
Pubmed	Human transcription factor protein interaction networks.	SFXN1 RNF214 FOXP4 KMT2D TCF20 ZFHX4 ATXN2 DDX52 MAZ NFYA AUTS2 FOXP1 ZFHX3 BCL9 RBM20 ZMYM4	4.60e-09	1429	64	16	35140242
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-25 ERVK-9	2.19e-08	94	64	6	21542922
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXP4 KMT2D SF3B1 MAP7D3 ZFHX4 DDX52 NFYA FOXP1 NBR1 CREB5 ZMYM4 LACTB	4.71e-08	857	64	12	25609649
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-19 ERVK-21	5.93e-08	5	64	3	12629516
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-19 ERVK-9	1.18e-07	6	64	3	15063128
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SFXN1 FOXP4 HIVEP2 ATXN2 AUTS2 FOXP1 ZFHX3 PRKCI LTBR MBD5 KAT6B PCDH1 NBR1 ZMYM4	4.20e-07	1489	64	14	28611215
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	FOXP4 KMT2D TCF20 ZFHX4 MAZ AUTS2 FOXP1 RBM20	6.94e-07	398	64	8	35016035
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-19 ERVK-21	7.07e-07	10	64	3	12970426
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXP4 KMT2D HIVEP2 ZFHX4 RHOXF2 MAZ NFYA GBX2 FOXP1 ZFHX3 CREB5	7.61e-07	908	64	11	19274049
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KMT2D TCF20 ZFHX4 FOXP1 ZFHX3 RBM20 MED12 ZMYM4	1.00e-06	418	64	8	34709266
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	KMT2D SF3B1 TCF20 ZFHX3 MED12 ZMYM4	3.30e-06	220	64	6	35785414
Pubmed	Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells.	FOXP1 HDAC7	3.33e-06	2	64	2	37507770
Pubmed	Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.	RHOXF2B RHOXF2	3.33e-06	2	64	2	12087094
Pubmed	Foxp1 and Foxp4 Deletion Causes the Loss of Follicle Stem Cell Niche and Cyclic Hair Shedding by Inducing Inner Bulge Cell Apoptosis.	FOXP4 FOXP1	3.33e-06	2	64	2	35759955
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	3.33e-06	2	64	2	9060628
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	3.33e-06	2	64	2	9460924
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	3.33e-06	2	64	2	10873665
Pubmed	Rhox homeobox gene cluster: recent duplication of three family members.	RHOXF2B RHOXF2	3.33e-06	2	64	2	16496311
Pubmed	Association of NRG1 and AUTS2 genetic polymorphisms with Hirschsprung disease in a South Chinese population.	NRG1 AUTS2	3.33e-06	2	64	2	29377512
Pubmed	Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.	RHOXF2B RHOXF2	3.33e-06	2	64	2	16465597
Pubmed	Cloning and characterization of the 5'-flanking region of the Ehox gene.	RHOXF2B RHOXF2	3.33e-06	2	64	2	16414020
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-25 ERVK-9	4.75e-06	18	64	3	18664271
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	ZFHX4 FOXP1 ZFHX3	6.63e-06	20	64	3	35177643
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	RHOXF2B FOXP4 ZFHX4 RHOXF2 GBX2 ZFHX3	9.17e-06	263	64	6	20932939
Pubmed	Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues.	FOXP4 FOXP1	9.99e-06	3	64	2	14516685
Pubmed	The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development.	RHOXF2B RHOXF2	9.99e-06	3	64	2	18562707
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	9.99e-06	3	64	2	10516026
Pubmed	Human-specific transcriptional regulation of CNS development genes by FOXP2.	FOXP4 FOXP1	9.99e-06	3	64	2	19907493
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-9	9.99e-06	3	64	2	9971820
Pubmed	Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, VLDLR and CNTNAP2 in the Zebra Finch Song System.	FOXP4 FOXP1	9.99e-06	3	64	2	28507505
Pubmed	The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c.	RHOXF2B RHOXF2	9.99e-06	3	64	2	18077458
Pubmed	Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization.	FOXP4 FOXP1	9.99e-06	3	64	2	25027557
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	FOXP4 KMT2D TCF20 FOXP1 BCL9 MED12	1.02e-05	268	64	6	33640491
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	KMT2D ATXN2 MED12	1.03e-05	23	64	3	9225980
Pubmed	Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.	FOXP4 ZFHX4 FOXP1	1.88e-05	28	64	3	29365100
Pubmed	Specification of jaw identity by the Hand2 transcription factor.	RHOXF2B RHOXF2 ZFHX3	1.88e-05	28	64	3	27329940
Pubmed	Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.	FOXP4 FOXP1	2.00e-05	4	64	2	14701752
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX4 ZFHX3	2.00e-05	4	64	2	23300874
Pubmed	NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo.	PRKCI NBR1	2.00e-05	4	64	2	20808283
Pubmed	Epithelium-generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness.	FOXP4 FOXP1	2.00e-05	4	64	2	27088802
Pubmed	Identification and characterization of T reg-like cells in zebrafish.	FOXP4 FOXP1	2.00e-05	4	64	2	29066577
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-19	2.00e-05	4	64	2	7983737
Pubmed	Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia.	SF3B1 FOXP1	2.00e-05	4	64	2	26460480
Pubmed	Rhox: a new homeobox gene cluster.	RHOXF2B RHOXF2	2.00e-05	4	64	2	15707895
Pubmed	Hereditary Ataxia Overview	FAT2 ATXN2 SPTBN2 ZFHX3	2.58e-05	92	64	4	20301317
Pubmed	Transcriptional genomics associates FOX transcription factors with human heart failure.	FOXP4 FOXP1	3.32e-05	5	64	2	16952980
Pubmed	Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.	RHOXF2B RHOXF2	3.32e-05	5	64	2	14648851
Pubmed	Human FOX gene family (Review).	FOXP4 FOXP1	3.32e-05	5	64	2	15492844
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF526 FAT2 TRPM3 SPTBN2 KIAA0586 MBD5 MED12	3.41e-05	493	64	7	15368895
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FOXP4 ZNF526 GTPBP2 ZFHX4 DDX52 MAZ RTL9 FOXP1 ZFHX3 KAT6B	3.49e-05	1116	64	10	31753913
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TCF20 ZFHX4 ZFHX3 ZMYM4	4.02e-05	103	64	4	32744500
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	RHOXF2B FOXP4 HIVEP2 TCF20 RHOXF2 RNF44 ZFHX3 KAT6B	4.64e-05	709	64	8	22988430
Pubmed	Aurothiomalate inhibits transformed growth by targeting the PB1 domain of protein kinase Ciota.	PRKCI NBR1	4.98e-05	6	64	2	16861740
Pubmed	Generation of mice with a conditional Foxp2 null allele.	FOXP4 FOXP1	4.98e-05	6	64	2	17619227
Pubmed	Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.	FOXP4 FOXP1	4.98e-05	6	64	2	28591638
Pubmed	Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.	KMT2D ATXN2	4.98e-05	6	64	2	8896557
Pubmed	Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6.	FOXP4 FOXP1	6.96e-05	7	64	2	20185820
Pubmed	Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.	FAT2 ATXN2 SPTBN2	8.53e-05	46	64	3	34815492
Pubmed	Disruption of MeCP2-TCF20 complex underlies distinct neurodevelopmental disorders.	SF3B1 TCF20	9.27e-05	8	64	2	35074918
Pubmed	Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.	FOXP4 GBX2 FOXP1 ZFHX3	9.95e-05	130	64	4	19386638
Pubmed	Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.	NRG1 FOXP1 CREB5	1.03e-04	49	64	3	35315772
Pubmed	Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.	FOXP4 GBX2 FOXP1 ZFHX3	1.12e-04	134	64	4	19030180
Pubmed	Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.	PRKCI NBR1	1.19e-04	9	64	2	12813044
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	KMT2D MAP7D3 KIAA0586 PRKCI HDAC7 NBR1 LACTB	1.21e-04	604	64	7	38803224
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	KIF18A KMT2D ATXN2 MAZ SPTBN2 PRKCI NBR1 RBM20 ADD2	1.24e-04	1049	64	9	27880917
Pubmed	Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development.	FOXP4 FOXP1	1.49e-04	10	64	2	28384713
Pubmed	Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.	RHOXF2B RHOXF2	1.49e-04	10	64	2	21972064
Pubmed	Foxp1/2/4 regulate endochondral ossification as a suppresser complex.	FOXP4 FOXP1	1.81e-04	11	64	2	25527076
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	KMT2D TCF20 ATXN2 AUTS2 BCL9 RBM20	1.96e-04	457	64	6	32344865
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KMT2D AUTS2 KAT6B HDAC7	2.06e-04	157	64	4	30186101
Pubmed	A major X-linked locus affects kidney function in mice.	RHOXF2B RHOXF2	2.17e-04	12	64	2	23011808
Pubmed	Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice.	RHOXF2B RHOXF2	2.17e-04	12	64	2	29500366
Pubmed	Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in Isl1 Conditional Mutants.	FOXP4 ZFHX3	2.57e-04	13	64	2	35273083
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	FOXP4 KMT2D MED12 ZMYM4	2.60e-04	167	64	4	20362541
Pubmed	A human MAP kinase interactome.	HIVEP2 SF3B1 TCF20 SPTBN2 NFYA MBD5	2.73e-04	486	64	6	20936779
Pubmed	TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology.	NRG1 AUTS2	2.99e-04	14	64	2	27979975
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	RNF214 MAP7D3 AUTS2 PRKCI NBR1	3.22e-04	322	64	5	39098523
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SF3B1 TCF20 ATXN2 MAZ CYP51A1 AUTS2 MED12 CREB5 ZMYM4	3.43e-04	1203	64	9	29180619
Pubmed	The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer.	FOXP4 ZFHX4 ZFHX3	3.65e-04	75	64	3	37298722
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SFXN1 RNF214 MAP7D3 ATXN2 RBMS3 MAZ LACTB	3.65e-04	724	64	7	36232890
Pubmed	CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth.	NRG1 ALOX12	3.93e-04	16	64	2	36239312
Pubmed	Differential expression of the Tmem132 family genes in the developing mouse nervous system.	GBX2 FOXP1	3.93e-04	16	64	2	35690356
Pubmed	The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.	FOXP4 FOXP1	3.93e-04	16	64	2	26021489
Pubmed	Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.	FOXP4 FOXP1	3.93e-04	16	64	2	22542185
Pubmed	Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.	ATXN2 SPTBN2	4.45e-04	17	64	2	15148151
Pubmed	Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.	NRG1 CREB5	4.45e-04	17	64	2	25436638
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	SFXN1 FOXP1 ZFHX3 MBD5 KAT6B NBR1	4.58e-04	536	64	6	15840001
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	TCF20 ATXN2 DDX52 MAZ ZMYM4	4.64e-04	349	64	5	25665578
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	SFXN1 FOXP1 ZFHX3 MBD5 KAT6B NBR1	4.67e-04	538	64	6	10512203
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	KMT2D TCF20 BCL9	4.92e-04	83	64	3	28794006
Pubmed	ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis.	RHOXF2B RHOXF2	5.00e-04	18	64	2	33842485
Pubmed	Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.	AUTS2 FOXP1	5.00e-04	18	64	2	30111840
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2D TCF20 MAP7D3 SPTBN2 MED12 ZMYM4	5.20e-04	549	64	6	38280479
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2D SF3B1 TCF20 BCL9 KAT6B HDAC7 ZMYM4	5.44e-04	774	64	7	15302935
Pubmed	Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.	GBX2 FOXP1	5.59e-04	19	64	2	26490861
Pubmed	Genome-wide association with bone mass and geometry in the Framingham Heart Study.	NRG1 RBMS3	5.59e-04	19	64	2	17903296
Pubmed	Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation.	NRG1 PRKCI	6.20e-04	20	64	2	26876178
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	SF3B1 NBR1 LACTB	6.64e-04	92	64	3	15840729
Interaction	CRX interactions	FOXP4 KMT2D TCF20 ZFHX4 RHOXF2 FOXP1 ZFHX3 PRKCI BCL9 MED12 ZMYM4	2.04e-10	254	60	11	int:CRX
Interaction	TLX1 interactions	FOXP4 KMT2D TCF20 ZFHX4 AUTS2 FOXP1 ZFHX3 BCL9 ZMYM4	2.31e-09	175	60	9	int:TLX1
Interaction	GSC interactions	FOXP4 KMT2D ZFHX4 AUTS2 FOXP1 ZFHX3 BCL9	7.01e-09	87	60	7	int:GSC
Interaction	EGR2 interactions	FOXP4 KMT2D HIVEP2 ZFHX4 FOXP1 ZFHX3 BCL9 ZMYM4	4.01e-08	171	60	8	int:EGR2
Interaction	LHX2 interactions	FOXP4 KMT2D ZFHX4 DDX52 FOXP1 ZFHX3 BCL9 ZMYM4	6.78e-08	183	60	8	int:LHX2
Interaction	PAX9 interactions	FOXP4 KMT2D TCF20 ZFHX4 FOXP1 ZFHX3 BCL9	1.15e-07	130	60	7	int:PAX9
Interaction	FOXL1 interactions	FOXP4 KMT2D SF3B1 ZFHX4 DDX52 FOXP1 ZFHX3 BCL9	1.15e-07	196	60	8	int:FOXL1
Interaction	FEV interactions	FOXP4 KMT2D TCF20 ZFHX4 FOXP1 ZFHX3 BCL9 ZMYM4	1.51e-07	203	60	8	int:FEV
Interaction	SOX7 interactions	FOXP4 KMT2D TCF20 ZFHX4 FOXP1 RBM20	1.58e-07	82	60	6	int:SOX7
Interaction	SOX5 interactions	FOXP4 KMT2D TCF20 ZFHX4 FOXP1 ZFHX3 ZMYM4	5.14e-07	162	60	7	int:SOX5
Interaction	TBR1 interactions	FOXP4 KMT2D ZFHX4 ZFHX3 BCL9 ZMYM4	1.06e-06	113	60	6	int:TBR1
Interaction	TBXT interactions	KMT2D TCF20 ZFHX4 FOXP1 BCL9 ZMYM4	1.24e-06	116	60	6	int:TBXT
Interaction	KLF5 interactions	FOXP4 KMT2D MAZ FOXP1 BCL9 RBM20 ZMYM4	1.78e-06	195	60	7	int:KLF5
Interaction	PAX7 interactions	FOXP4 KMT2D ZFHX4 FOXP1 ZFHX3 BCL9	1.83e-06	124	60	6	int:PAX7
Interaction	ERG interactions	FOXP4 KMT2D SF3B1 TCF20 ZFHX4 FOXP1 BCL9	4.34e-06	223	60	7	int:ERG
Interaction	PAX2 interactions	FOXP4 KMT2D ZFHX4 FOXP1 BCL9	5.39e-06	85	60	5	int:PAX2
Interaction	FOXI1 interactions	FOXP4 KMT2D ZFHX4 FOXP1 BCL9	7.96e-06	92	60	5	int:FOXI1
Interaction	LHX3 interactions	FOXP4 KMT2D TCF20 ZFHX4 FOXP1 BCL9	1.83e-05	185	60	6	int:LHX3
Interaction	PAX8 interactions	FOXP4 KMT2D ZFHX4 FOXP1 BCL9	1.99e-05	111	60	5	int:PAX8
Interaction	HNF1B interactions	KMT2D ZFHX4 FOXP1 ZFHX3 BCL9 ZMYM4	2.13e-05	190	60	6	int:HNF1B
Interaction	TLX3 interactions	FOXP4 KMT2D TCF20 ZFHX4 FOXP1 ZFHX3 BCL9	2.44e-05	291	60	7	int:TLX3
Interaction	SP7 interactions	FOXP4 KMT2D TCF20 ZFHX4 FOXP1 BCL9 RBM20	3.23e-05	304	60	7	int:SP7
Interaction	VSX1 interactions	FOXP4 ZFHX4 FOXP1 ZFHX3	4.46e-05	66	60	4	int:VSX1
Interaction	TLX2 interactions	FOXP4 KMT2D TCF20 ZFHX3 BCL9	6.47e-05	142	60	5	int:TLX2
Interaction	ZFHX4 interactions	FOXP4 ZFHX4 FOXP1 ZFHX3	6.63e-05	73	60	4	int:ZFHX4
Interaction	SOX6 interactions	FOXP4 TCF20 ZFHX4 FOXP1 ZFHX3	1.04e-04	157	60	5	int:SOX6
Interaction	IRF4 interactions	FOXP4 KMT2D TCF20 FOXP1	1.20e-04	85	60	4	int:IRF4
Interaction	TLE3 interactions	KMT2D HIVEP2 TCF20 AUTS2 ZFHX3 BCL9 RBM20	1.23e-04	376	60	7	int:TLE3
Interaction	LHX4 interactions	FOXP4 KMT2D DDX52 BCL9 ZMYM4	1.35e-04	166	60	5	int:LHX4
Interaction	TEAD1 interactions	KMT2D ZFHX4 MAZ FOXP1 ZFHX3	1.78e-04	176	60	5	int:TEAD1
Interaction	SOX17 interactions	FOXP4 KMT2D TCF20 BCL9	1.85e-04	95	60	4	int:SOX17
Interaction	ALG13 interactions	KMT2D TCF20 ATXN2 BCL9 RBM20	2.13e-04	183	60	5	int:ALG13
Interaction	NME2P1 interactions	ATXN2 NFYA C11orf24 MBD5	2.16e-04	99	60	4	int:NME2P1
Interaction	LHX1 interactions	FOXP4 KMT2D ZFHX4 BCL9	2.52e-04	103	60	4	int:LHX1
Interaction	GATA2 interactions	KMT2D ZFHX4 FOXP1 ZFHX3 BCL9	3.14e-04	199	60	5	int:GATA2
Interaction	SMG7 interactions	RNF214 KMT2D TCF20 ATXN2 BCL9 RBM20	3.66e-04	319	60	6	int:SMG7
Interaction	SLC66A1LP interactions	PRKCI NBR1	3.86e-04	10	60	2	int:SLC66A1LP
Interaction	NFIC interactions	FOXP4 KMT2D SF3B1 FOXP1 ZMYM4	4.02e-04	210	60	5	int:NFIC
GeneFamily	Ataxins\|Trinucleotide repeat containing	KMT2D ATXN2 MED12	2.78e-05	25	43	3	775
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX3	5.69e-04	15	43	2	529
Coexpression	GSE360_DC_VS_MAC_DN	FAT2 HIVEP2 DDX52 NFYA GBX2 ZFHX3	5.03e-06	198	58	6	M5173
Coexpression	GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP	TCF20 FOXP1 MBD5 KAT6B HDAC7	2.20e-05	152	58	5	M2938
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN	TCF20 FOXP1 MBD5 KAT6B HDAC7	2.98e-05	162	58	5	M7002
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	TCF20 RBMS3 NFYA AUTS2 ZFHX3 BCL9 LACTB	7.48e-05	467	58	7	M1347
Coexpression	GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP	TCF20 C11orf24 BCL9 HDAC7 MED12	7.93e-05	199	58	5	M7254
Coexpression	GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN	KMT2D HIVEP2 SF3B1 ATXN2 BCL9	8.12e-05	200	58	5	M3510
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	TCF20 RBMS3 NFYA AUTS2 ZFHX3 BCL9 LACTB	9.34e-05	484	58	7	MM999
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP2 ENOX1 ZFHX4 TRPM3 RBMS3 AUTS2	1.24e-07	179	58	6	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	NRG1 TRPM3 RBMS3 FOXP1 FGD5	4.75e-06	189	58	5	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ENOX1 RBMS3 AUTS2 ZFHX3 CREB5	4.87e-06	190	58	5	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	COL4A3 HIVEP2 RBMS3 ZFHX3 CREB5	5.25e-06	193	58	5	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 CYP51A1 FOXP1 ALOX12 RBM20	5.25e-06	193	58	5	55eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	COL4A3 HIVEP2 RBMS3 ZFHX3 CREB5	5.39e-06	194	58	5	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF526 ATXN2 FOXP1 ZMYM4	6.96e-05	169	58	4	f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	COL4A3 NRG1 RBMS3 CYP51A1	7.62e-05	173	58	4	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FOXP1 FGD5 PCDH1 HDAC7	7.79e-05	174	58	4	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 TINAG TRPM3 CREB5	8.69e-05	179	58	4	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 TRPM3 ZFHX3 RBM20	8.69e-05	179	58	4	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	SNX7 C11orf24 ZFHX3 CREB5	9.07e-05	181	58	4	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP2 ENOX1 ZFHX4 TRPM3	9.27e-05	182	58	4	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 TRPM3 ZFHX3 RBM20	9.47e-05	183	58	4	65f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	NRG1 TINAG TRPM3 CREB5	9.67e-05	184	58	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	SNX7 C11orf24 ZFHX3 CREB5	9.67e-05	184	58	4	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	droplet-Tongue-nan-24m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 CYP51A1 FOXP1 ALOX12	1.01e-04	186	58	4	18c06041c6c8a0ebac17b3c8aaebd67e652d315a
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	NRG1 TINAG TRPM3 CREB5	1.03e-04	187	58	4	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A3 RBMS3 ZFHX3 CREB5	1.03e-04	187	58	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A3 NRG1 TINAG TRPM3	1.03e-04	187	58	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 FGD5 HDAC7 ALOX12	1.05e-04	188	58	4	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	NRG1 TRPM3 FOXP1 FGD5	1.07e-04	189	58	4	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 TINAG TRPM3 CREB5	1.07e-04	189	58	4	28b502611829e4a24caff2562545c7db97686099
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NRG1 FOXP1 FGD5 ALOX12	1.07e-04	189	58	4	360f09f46231a83f99d8fa0158b72a38068e1642
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRG1 RBMS3 FOXP1 FGD5	1.07e-04	189	58	4	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	NRG1 TINAG TRPM3 CREB5	1.07e-04	189	58	4	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 FGD5 HDAC7 ALOX12	1.09e-04	190	58	4	25525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 FGD5 HDAC7 ALOX12	1.09e-04	190	58	4	a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FOXP1 FGD5 PCDH1 HDAC7	1.09e-04	190	58	4	5130fb325f80f591b9b36beacb8072c4472304f2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 TINAG TRPM3 CREB5	1.09e-04	190	58	4	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FOXP1 FGD5 PCDH1 HDAC7	1.09e-04	190	58	4	1357bd4527399d7013ee33272bda7453f472999a
ToppCell	droplet-Tongue-nan-3m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP51A1 PCDH1 ALOX12 CLDN23	1.12e-04	191	58	4	abdd93b2313e635f75a750d051a6a01ddc4e2df9
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	NRG1 TRPM3 FOXP1 FGD5	1.14e-04	192	58	4	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	NRG1 RBMS3 FOXP1 FGD5	1.19e-04	194	58	4	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	COL4A3 RBMS3 ZFHX3 CREB5	1.19e-04	194	58	4	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 HIVEP2 TRPM3 FOXP1	1.21e-04	195	58	4	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL4A3 RBMS3 ZFHX3 CREB5	1.21e-04	195	58	4	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL4A3 TDRD5 NRG1 TRPM3	1.28e-04	198	58	4	5a85c286f79cde5811d2595a3397c6fb7685adee
ToppCell	Caecum-(6)_Macrophage\|Caecum / shred on region, Cell_type, and subtype	NRG1 ZFHX3 LTBR CREB5	1.33e-04	200	58	4	2ce3930645c3daf6be578f7881e57a58df61e75c
ToppCell	Caecum-Macrophage\|Caecum / Region, Cell class and subclass	NRG1 ZFHX3 LTBR CREB5	1.33e-04	200	58	4	d83209559187a4419df2508ecc5eb9f7d72fced3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	ZFHX4 MAZ AUTS2 ZFHX3	1.33e-04	200	58	4	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ENOX1 ZFHX4 RBMS3 ADD2	1.33e-04	200	58	4	c082bc21ec7c5323439d108ea8aea510e1113c3f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	FOXP4 ZFHX4 AUTS2 FOXP1	1.33e-04	200	58	4	f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
Disease	unipolar depression	NRG1 HIVEP2 SF3B1 ENOX1 TRPM3 RBMS3 AUTS2 ZFHX3 PCDH1 MED12 CLDN23 CREB5 ZMYM4	3.06e-07	1206	56	13	EFO_0003761
Disease	bipolar disorder	KIF18A KMT2D HIVEP2 SF3B1 TCF20 RBMS3 SPTBN2 AUTS2 HDAC7	1.31e-06	577	56	9	MONDO_0004985
Disease	autosomal dominant intellectual developmental disorder (implicated_via_orthology)	AUTS2 MBD5	1.06e-05	3	56	2	DOID:0060307 (implicated_via_orthology)
Disease	specific developmental disorder (implicated_via_orthology)	FOXP4 FOXP1	2.12e-05	4	56	2	DOID:0060038 (implicated_via_orthology)
Disease	Phyllodes Tumor	KMT2D MED12	3.52e-05	5	56	2	C0010701
Disease	Malignant Cystosarcoma Phyllodes	KMT2D MED12	3.52e-05	5	56	2	C0600066
Disease	pulse pressure measurement	NRG1 ZFHX4 TRPM3 CYP51A1 FOXP1 ZFHX3 FGD5 MBD5 CLDN23 CREB5 LACTB	5.20e-05	1392	56	11	EFO_0005763
Disease	LDL cholesterol change measurement, response to simvastatin, response to fenofibrate	SNX7 FOXP1	9.83e-05	8	56	2	EFO_0007804, GO_1901557, GO_1903491
Disease	vital capacity	NRG1 HIVEP2 TCF20 SPTBN2 RTL9 AUTS2 FOXP1 ZFHX3 RBM20 CREB5	9.85e-05	1236	56	10	EFO_0004312
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	NRG1 FOXP1 KAT6B ALOX12	1.14e-04	131	56	4	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	NRG1 FOXP1 KAT6B ALOX12	1.14e-04	131	56	4	C4552091
Disease	Juvenile arthritis	NRG1 FOXP1 KAT6B ALOX12	1.14e-04	131	56	4	C3495559
Disease	Juvenile psoriatic arthritis	NRG1 FOXP1 KAT6B ALOX12	1.14e-04	131	56	4	C3714758
Disease	cognitive inhibition measurement	HIVEP2 TCF20 RBMS3	1.19e-04	50	56	3	EFO_0007969
Disease	Global developmental delay	GTPBP2 TCF20 TRPM3 SPTBN2	1.21e-04	133	56	4	C0557874
Disease	Juvenile-Onset Still Disease	NRG1 FOXP1 KAT6B ALOX12	1.28e-04	135	56	4	C0087031
Disease	Intellectual Disability	ZNF526 GTPBP2 HIVEP2 TCF20 MAP7D3 TRPM3	2.00e-04	447	56	6	C3714756
Disease	Paroxysmal atrial fibrillation	ZFHX3 MBD5 RBM20 CREB5	2.23e-04	156	56	4	C0235480
Disease	familial atrial fibrillation	ZFHX3 MBD5 RBM20 CREB5	2.23e-04	156	56	4	C3468561
Disease	Persistent atrial fibrillation	ZFHX3 MBD5 RBM20 CREB5	2.23e-04	156	56	4	C2585653
Disease	Atrial Fibrillation	ZFHX3 MBD5 RBM20 CREB5	2.46e-04	160	56	4	C0004238
Disease	Schizophrenia	NRG1 ATXN2 SPTBN2 ERVK-8 AUTS2 BCL9 ALOX12 MED12	2.48e-04	883	56	8	C0036341
Disease	sclerosing cholangitis	ATXN2 FOXP1 HDAC7	2.72e-04	66	56	3	EFO_0004268
Disease	cardioembolic stroke	RBMS3 ZFHX3 RBM20 OR4D2	3.09e-04	170	56	4	EFO_1001976
Disease	response to ketamine	FOXP1 ZFHX3 ADD2	3.10e-04	69	56	3	EFO_0009748
Disease	mean arterial pressure	TCF20 ATXN2 AUTS2 ZFHX3 FGD5 HDAC7	3.60e-04	499	56	6	EFO_0006340
Disease	Ischemic stroke	NRG1 FOXP4 ATXN2 AUTS2 ZFHX3	3.74e-04	324	56	5	HP_0002140
Disease	neutrophil-to-lymphocyte ratio	ATXN2 FOXP1 LTBR CREB5	4.26e-04	185	56	4	EFO_0008447
Disease	autosomal dominant compelling helio-ophthalmic outburst syndrome	ENOX1 AUTS2 ZFHX3	4.29e-04	77	56	3	EFO_0007887
Disease	sphingomyelin 14:0 measurement	TRPM3 ZFHX3	4.72e-04	17	56	2	EFO_0010390
Disease	electrocardiography	NRG1 TRPM3 SNX7 FOXP1 KAT6B RBM20	4.95e-04	530	56	6	EFO_0004327
Disease	response to selective serotonin reuptake inhibitor	NRG1 TRPM3 AUTS2	5.16e-04	82	56	3	EFO_0005658
Disease	hematocrit	COL4A3 NRG1 HIVEP2 ATXN2 RBMS3 CYP51A1 FOXP1 FGD5	6.10e-04	1011	56	8	EFO_0004348
Disease	atrial fibrillation	ZFHX4 ZFHX3 MBD5 RBM20 CREB5	6.90e-04	371	56	5	EFO_0000275
Disease	Precursor B-cell lymphoblastic leukemia	AUTS2 FOXP1	7.26e-04	21	56	2	C1292769
Disease	obesity (implicated_via_orthology)	ZFHX4 ZFHX3 PRKCI MED12	7.48e-04	215	56	4	DOID:9970 (implicated_via_orthology)
Disease	small vessel stroke	NRG1 ENOX1 ATXN2	8.16e-04	96	56	3	EFO_1001504
Disease	gastroesophageal reflux disease	HIVEP2 ATXN2 FOXP1	9.46e-04	101	56	3	EFO_0003948
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	TCF20 ATXN2 LACTB	1.00e-03	103	56	3	EFO_0008595, EFO_0020944
Disease	lifestyle measurement	HIVEP2 AUTS2 FOXP1 PCDH1	1.04e-03	235	56	4	EFO_0010724
Disease	glomerular filtration rate, response to platinum based chemotherapy	RBMS3 BCL9	1.30e-03	28	56	2	EFO_0004647, EFO_0005208
Disease	chronotype measurement	NRG1 FOXP4 KMT2D TCF20 AUTS2 FOXP1 CLDN23	1.35e-03	882	56	7	EFO_0008328
Disease	bipolar disorder (is_implicated_in)	NRG1 KAT6B	1.39e-03	29	56	2	DOID:3312 (is_implicated_in)
Disease	lymphocyte measurement	ATXN2 LTBR RBM20	1.45e-03	117	56	3	EFO_0803546
Disease	Crohn's disease	TRPM3 ATXN2 RBMS3 FOXP1 LTBR	1.49e-03	441	56	5	EFO_0000384
Disease	tonsillectomy risk measurement	TRPM3 ATXN2 LTBR ALOX12	1.51e-03	260	56	4	EFO_0007924
Disease	Hirschsprung Disease	NRG1 MED12	1.59e-03	31	56	2	C0019569
Disease	Antihypertensive use measurement	HIVEP2 ATXN2 AUTS2 FGD5	1.62e-03	265	56	4	EFO_0009927
Disease	diastolic blood pressure, systolic blood pressure	NRG1 TRPM3 ATXN2 ZFHX3 BCL9 CREB5	1.66e-03	670	56	6	EFO_0006335, EFO_0006336
Disease	insulin measurement	FOXP4 RBMS3 SNX7 HDAC7	1.66e-03	267	56	4	EFO_0004467

Protein segments in the cluster

Peptide	Gene	Start	Entry
QPTSNMEPPKQIMSM	TDRD5	241	Q8NAT2
QMPTPIQMQAIPVML	DDX52	186	Q9Y2R4
LMIVSMVVSLPMPAG	ERVK-19	81	O71037
LMIVSMVVSLPMPAG	ERVK-8	81	Q902F8
LMIVSMVVSLPMPAG	ERVK-9	81	Q9UKH3
PALMPMNMAPITGRA	COL4A3	1526	Q01955
MVMVSPEMNPTICSV	GTPBP2	491	Q9BX10
PSAMVMHPFTGVMPQ	RBM20	191	Q5T481
VITPTMDHPMSMQPA	RBMS3	316	Q6XE24
EMSPPVSSMTVSMPS	NRG1	451	Q02297
ISVPSLQNMETSPMM	KAT6B	1636	Q8WYB5
PTMPGSSAVLMPMER	CREB5	186	Q02930
VSIGHTVMTPMLNPM	OR4D2	271	P58180
PQEPVMPMDQSSMHS	PRKCI	196	P41743
GQTMPMVPPLDFTMN	MED14OS	116	P0DP75
MPVPSMVPSYMAMTT	KIF18A	811	Q8NI77
TAHAPMMLMTTQPPG	ATXN2	1261	Q99700
KPETMVMMWTPVPNT	LACTB	436	P83111
NPMTPVTPMTSMTSM	BAIAP2L2	391	Q6UXY1
VTPMTSMTSMSPMTP	BAIAP2L2	396	Q6UXY1
SMTSMSPMTPMNPGN	BAIAP2L2	401	Q6UXY1
VQMRSAMPMVPCQGP	FAT2	3716	Q9NYQ8
VMENMPALSPVGMVT	PCDH1	621	Q08174
PPTLVPVTHVMMCMN	FGD5	1236	Q6ZNL6
PVSVAMMTPQVITPQ	FOXP1	96	Q9H334
SMPMTVGVTGIHPMN	AUTS2	1021	Q8WXX7
PSGAMKMPTMVPLSL	MAZ	221	P56270
LQQTPMISTMTPMSA	MED12	2021	Q93074
VPVSVAMMSPQMLTP	FOXP4	101	Q8IVH2
MRMPPPTTKEDVTMA	ALOX12	561	P18054
PPSLMMMQRPLGSST	GBX2	6	P52951
LMIVSMVVSLPMPAG	ERVK-25	81	P61570
LMIVSMVVSLPMPAG	ERVK-6	81	Q69384
VVPMPTLSPMGMTQP	BCL9	1071	O00512
PPIMIMMRMARTPQT	CYP51A1	381	Q16850
MIVSMVVSLPMPAGA	ERVK-21	81	P61565
AVMFPMSTMKIPPQT	MAP7D3	271	Q8IWC1
HSQVPMMNVSMPPAV	MBD5	386	Q9P267
MMNVSMPPAVVPLPS	MBD5	391	Q9P267
LMIVSMVVSLPMPAG	HERVK_113	81	Q902F9
RSVEPMRLSMDTPMP	HDAC7	41	Q8WUI4
LNMMTGITPINPMIP	ENOX1	81	Q8TC92
MRTPVVMTLGMVLAP	CLDN23	1	Q96B33
MVMMVPGAGSVPAIQ	NFYA	236	P23511
MSPALMTALPSGVMP	RTL9	346	Q8NET4
MTALPSGVMPTQTMP	RTL9	351	Q8NET4
MAAPGMAIPPFIMNT	SFXN1	236	Q9H9B4
TLMLPLQPCTSVMPM	NBR1	356	Q14596
MLPFMAVGQPVMVTA	RHOXF2B	201	P0C7M4
FSPMMPTSPLSMINQ	SNX7	6	Q9UNH6
TMDPVMMTVSPPPAH	SPEM1	96	Q8N4L4
VFPTSSMNVSMMTPI	ADD2	101	P35612
QLMMPICPMALNSTT	C21orf62-AS1	6	Q17RA5
EMEAMSPTTQPSPMP	C11orf24	316	Q96F05
PRMPFSIGQVTMPMV	RNF214	461	Q8ND24
SIGQVTMPMVMPSAD	RNF214	466	Q8ND24
TMPMVMPSADPRSLS	RNF214	471	Q8ND24
MTVPVPDVMMPNSML	ZFHX4	1236	Q86UP3
PDVMMPNSMLLPAAA	ZFHX4	1241	Q86UP3
TRGMTRAMTMPPVSP	SPTBN2	2346	O15020
NMATPTPGHIMSMTP	SF3B1	366	O75533
ETMSPTSPTLMPRMR	TRPM3	1346	Q9HCF6
MLPMSPTAMGPTISL	RNF44	311	Q7L0R7
MLPFMAVGQPVMVTA	RHOXF2	201	Q9BQY4
ILQLMPQLSPTPSMM	TCF20	411	Q9UGU0
PLPPEMSGTMLMLAV	LTBR	216	P36941
MPTQMSPGAVEMSTP	ZNF526	11	Q8TF50
PPSPMLLSMNEMTAS	TINAG	196	Q9UJW2
IPMVPVGGIQMVHSM	HIVEP2	2226	P31629
MPVPMLIPSSMDSED	ZMYM4	1011	Q5VZL5
SASQMPPAKMSVMLP	KIAA0586	1491	Q9BVV6
TPEMVMPSSMFLPAA	ZFHX3	1291	Q15911
VLSQKPMGTMPPSMC	KMT2D	3376	O14686