Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ZNF689 SKOR1 ZNF620 ZNF74 ZKSCAN4 ZNF658B PRDM2 ZFX ZFY ZNF331	1.99e-08	1412	67	20	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ZNF689 SKOR1 ZNF620 ZNF74 ZKSCAN4 ZNF658B PRDM2 ZFX ZFY ZNF331	1.87e-07	1459	67	19	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ZNF689 SKOR1 ZNF74 ZKSCAN4 ZNF658B ZFX ZFY ZNF331	4.96e-07	1244	67	17	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ZNF689 SKOR1 ZNF74 ZKSCAN4 ZNF658B ZFX ZFY ZNF331	6.69e-07	1271	67	17	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	RLF ZNF131 ZBTB17 ZNF658 MTF1 ZNF658B PRDM2 ZFX ZFY	1.01e-04	560	67	9	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	RLF ZNF131 ZBTB17 ZNF658 MTF1 ZNF658B PRDM2 ZFX ZFY	1.10e-04	566	67	9	GO:0001216
GeneOntologyMolecularFunction	chromatin insulator sequence binding	ZFX ZFY	2.30e-04	7	67	2	GO:0043035
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF93 ZNF131 ZBTB49 ZBTB17 ZKSCAN4 PRDM2	7.10e-04	320	67	6	GO:0001227
GeneOntologyMolecularFunction	zinc ion binding	ZNF93 DHX58 USP51 ADAMTS9 ADAMTS20 SLU7 ZNF407 GRIN2B PRDM2 ZNF331	7.33e-04	891	67	10	GO:0008270
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF93 ZNF131 ZBTB49 ZBTB17 ZKSCAN4 PRDM2	7.82e-04	326	67	6	GO:0001217
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNA6 GRIK3 GRIN2B	9.28e-04	57	67	3	GO:1904315
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	CHRNA6 GRIK3 GRIN2B	1.08e-03	60	67	3	GO:0099529
GeneOntologyMolecularFunction	transmitter-gated channel activity	CHRNA6 GRIK3 GRIN2B	1.36e-03	65	67	3	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	CHRNA6 GRIK3 GRIN2B	1.36e-03	65	67	3	GO:0022824
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIK3 GRIN2B	1.46e-03	17	67	2	GO:0004970
GeneOntologyMolecularFunction	transition metal ion binding	ZNF93 DHX58 USP51 ADAMTS9 AOX1 ADAMTS20 SLU7 ZNF407 GRIN2B PRDM2 ZNF331	1.89e-03	1189	67	11	GO:0046914
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	CHRNA6 GRIK3 GRIN2B	2.05e-03	75	67	3	GO:0098960
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	CHRNA6 GRIK3 GRIN2B	2.21e-03	77	67	3	GO:0005230
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIK3 GRIN2B	2.92e-03	24	67	2	GO:0099507
GeneOntologyMolecularFunction	glutamate receptor activity	GRIK3 GRIN2B	3.69e-03	27	67	2	GO:0008066
GeneOntologyMolecularFunction	neurotransmitter receptor activity	CHRNA6 GRIK3 GRIN2B	4.63e-03	100	67	3	GO:0030594
GeneOntologyBiologicalProcess	regulation of developmental pigmentation	ADAMTS9 ADAMTS20 IHH	1.32e-05	15	65	3	GO:0048070
GeneOntologyBiologicalProcess	regulation of pigmentation	ADAMTS9 ADAMTS20 IHH	1.97e-05	17	65	3	GO:0120305
GeneOntologyBiologicalProcess	ionotropic glutamate receptor signaling pathway	TIAM1 GRIK3 GRIN2B	8.28e-05	27	65	3	GO:0035235
GeneOntologyBiologicalProcess	positive regulation of melanocyte differentiation	ADAMTS9 ADAMTS20	9.72e-05	5	65	2	GO:0045636
GeneOntologyBiologicalProcess	NMDA selective glutamate receptor signaling pathway	TIAM1 GRIN2B	1.45e-04	6	65	2	GO:0098989
GeneOntologyBiologicalProcess	positive regulation of pigment cell differentiation	ADAMTS9 ADAMTS20	2.03e-04	7	65	2	GO:0050942
GeneOntologyBiologicalProcess	regulation of melanocyte differentiation	ADAMTS9 ADAMTS20	2.03e-04	7	65	2	GO:0045634
GeneOntologyBiologicalProcess	ligand-gated ion channel signaling pathway	TIAM1 GRIK3 GRIN2B	2.72e-04	40	65	3	GO:1990806
GeneOntologyBiologicalProcess	double-strand break repair via homologous recombination	USP51 SLF2 ARID2 REV3L HELQ	3.16e-04	188	65	5	GO:0000724
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	RLF ZNF131 ZBTB49 ZBTB17 ZNF658 MTF1 ARID2 ZNF407 IHH ZNF658B PRDM2 ZFX ZFY	3.40e-04	1390	65	13	GO:0045944
GeneOntologyBiologicalProcess	positive regulation of developmental pigmentation	ADAMTS9 ADAMTS20	3.47e-04	9	65	2	GO:0048087
GeneOntologyBiologicalProcess	regulation of pigment cell differentiation	ADAMTS9 ADAMTS20	3.47e-04	9	65	2	GO:0050932
GeneOntologyBiologicalProcess	recombinational repair	USP51 SLF2 ARID2 REV3L HELQ	3.65e-04	194	65	5	GO:0000725
Domain	ZINC_FINGER_C2H2_2	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ARID2 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	6.30e-13	775	64	20	PS50157
Domain	-	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	6.57e-13	679	64	19	3.30.160.60
Domain	ZINC_FINGER_C2H2_1	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ARID2 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	6.61e-13	777	64	20	PS00028
Domain	zf-C2H2	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	9.41e-13	693	64	19	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	9.65e-13	694	64	19	IPR013087
Domain	Znf_C2H2-like	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ARID2 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	1.03e-12	796	64	20	IPR015880
Domain	Znf_C2H2	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ARID2 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	1.27e-12	805	64	20	IPR007087
Domain	ZnF_C2H2	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 MTF1 ZNF41 ARID2 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 PRDM2 ZFX ZFY ZNF331	1.36e-12	808	64	20	SM00355
Domain	KRAB	ZNF93 ZNF776 ZNF547 ZNF658 ZNF41 ZNF689 ZNF620 ZNF74 ZKSCAN4 ZNF331	3.57e-07	358	64	10	PS50805
Domain	KRAB	ZNF93 ZNF776 ZNF547 ZNF658 ZNF41 ZNF689 ZNF620 ZNF74 ZKSCAN4 ZNF331	3.57e-07	358	64	10	PF01352
Domain	KRAB	ZNF93 ZNF776 ZNF547 ZNF658 ZNF41 ZNF689 ZNF620 ZNF74 ZKSCAN4 ZNF331	4.71e-07	369	64	10	SM00349
Domain	KRAB	ZNF93 ZNF776 ZNF547 ZNF658 ZNF41 ZNF689 ZNF620 ZNF74 ZKSCAN4 ZNF331	4.82e-07	370	64	10	IPR001909
Domain	Pept_M12B_GON-ADAMTSs	ADAMTS9 ADAMTS20	1.16e-05	2	64	2	IPR012314
Domain	GON	ADAMTS9 ADAMTS20	1.16e-05	2	64	2	PF08685
Domain	GON	ADAMTS9 ADAMTS20	1.16e-05	2	64	2	PS51046
Domain	Zfx_Zfy_act	ZFX ZFY	3.46e-05	3	64	2	PF04704
Domain	DUF3496	ANKRD26 CCDC144A	3.46e-05	3	64	2	IPR021885
Domain	Transcrp_activ_Zfx/Zfy-dom	ZFX ZFY	3.46e-05	3	64	2	IPR006794
Domain	DUF3496	ANKRD26 CCDC144A	3.46e-05	3	64	2	PF12001
Domain	zf-C2H2_6	ZNF93 ZBTB49 ZNF658 ZNF620 ZKSCAN4 PRDM2 ZNF331	9.71e-05	314	64	7	PF13912
Domain	Iontro_rcpt	GRIK3 GRIN2B	1.71e-03	18	64	2	IPR001320
Domain	Lig_chan-Glu_bd	GRIK3 GRIN2B	1.71e-03	18	64	2	PF10613
Domain	Iono_rcpt_met	GRIK3 GRIN2B	1.71e-03	18	64	2	IPR001508
Domain	Glu/Gly-bd	GRIK3 GRIN2B	1.71e-03	18	64	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIK3 GRIN2B	1.71e-03	18	64	2	SM00918
Domain	Lig_chan	GRIK3 GRIN2B	1.71e-03	18	64	2	PF00060
Domain	PBPe	GRIK3 GRIN2B	1.71e-03	18	64	2	SM00079
Domain	ADAM_spacer1	ADAMTS9 ADAMTS20	2.79e-03	23	64	2	IPR010294
Domain	ADAM_spacer1	ADAMTS9 ADAMTS20	2.79e-03	23	64	2	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS9 ADAMTS20	3.04e-03	24	64	2	IPR013273
Domain	Helicase_C	DHX58 DDX60L HELQ	5.91e-03	107	64	3	PF00271
Domain	HELICc	DHX58 DDX60L HELQ	5.91e-03	107	64	3	SM00490
Domain	Helicase_C	DHX58 DDX60L HELQ	6.07e-03	108	64	3	IPR001650
Domain	HELICASE_CTER	DHX58 DDX60L HELQ	6.22e-03	109	64	3	PS51194
Domain	HELICASE_ATP_BIND_1	DHX58 DDX60L HELQ	6.22e-03	109	64	3	PS51192
Domain	DEXDc	DHX58 DDX60L HELQ	6.22e-03	109	64	3	SM00487
Domain	Helicase_ATP-bd	DHX58 DDX60L HELQ	6.38e-03	110	64	3	IPR014001
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF776 ZNF547 ZNF658 ZNF41 INTS13 ARID2 ZNF689 ZNF620 SLU7 ZNF74 PRKCQ GRIN2B ZKSCAN4 IHH ZNF331	9.73e-05	1387	52	15	M734
Pubmed	The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).	CFB ZFX ZFY	6.81e-08	5	67	3	9244432
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF93 ZNF776 ZNF41 ZNF689 ZNF620 ZNF74	1.40e-06	181	67	6	37372979
Pubmed	Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.	ZFX ZFY	3.66e-06	2	67	2	12716983
Pubmed	Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.	ZFX ZFY	3.66e-06	2	67	2	9126493
Pubmed	Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.	ZFX ZFY	3.66e-06	2	67	2	19329779
Pubmed	Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs.	ZFX ZFY	3.66e-06	2	67	2	1970799
Pubmed	Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.	ZFX ZFY	3.66e-06	2	67	2	8487630
Pubmed	Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.	ZFX ZFY	3.66e-06	2	67	2	1691708
Pubmed	The structure of the Zfx gene on the mouse X chromosome.	ZFX ZFY	3.66e-06	2	67	2	8188262
Pubmed	Comparison of human ZFY and ZFX transcripts.	ZFX ZFY	3.66e-06	2	67	2	2308929
Pubmed	Mapping the human ZFX locus to Xp21.3 by in situ hybridization.	ZFX ZFY	3.66e-06	2	67	2	2497060
Pubmed	RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.	ZFX ZFY	3.66e-06	2	67	2	28251288
Pubmed	Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.	ZFX ZFY	3.66e-06	2	67	2	2041734
Pubmed	Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.	ZFX ZFY	3.66e-06	2	67	2	8318216
Pubmed	Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.	ZFX ZFY	3.66e-06	2	67	2	2105457
Pubmed	Circ_0000520 contributes to triple-negative breast cancer progression through mediating the miR-1296/ZFX axis.	ZFX ZFY	3.66e-06	2	67	2	34324278
Pubmed	Zfx mutation results in small animal size and reduced germ cell number in male and female mice.	ZFX ZFY	3.66e-06	2	67	2	9187153
Pubmed	[Expression of Zfx in mouse testicular spermatogenic cells].	ZFX ZFY	3.66e-06	2	67	2	38602753
Pubmed	Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.	ADAMTS9 ADAMTS20	3.66e-06	2	67	2	12514189
Pubmed	Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.	ZFX ZFY	3.66e-06	2	67	2	2265557
Pubmed	Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.	ZFX ZFY	1.10e-05	3	67	2	2480529
Pubmed	Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior.	NBEA GRIN2B	1.10e-05	3	67	2	29847800
Pubmed	Genetic dissection of mammalian fertility pathways.	ZFX ZFY	1.10e-05	3	67	2	12479614
Pubmed	Isolation of monochromosomal hybrids for mouse chromosomes 3, 6, 10, 12, 14, and 18.	ZFX ZFY	1.10e-05	3	67	2	9060403
Pubmed	Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling.	ZFX ZFY	1.10e-05	3	67	2	38310188
Pubmed	Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate.	ADAMTS9 ADAMTS20	1.10e-05	3	67	2	37169079
Pubmed	YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.	ZFX ZFY	1.10e-05	3	67	2	8406471
Pubmed	A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.	ADAMTS9 ADAMTS20	1.10e-05	3	67	2	24753090
Pubmed	X chromosome genes and premature ovarian failure.	ZFX ZFY	1.10e-05	3	67	2	11299520
Pubmed	The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines.	TIAM1 GRIN2B	1.10e-05	3	67	2	15721239
Pubmed	Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.	ZFX ZFY	1.10e-05	3	67	2	32406922
Pubmed	ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.	ZFX ZFY	2.19e-05	4	67	2	24485662
Pubmed	Zfx controls the self-renewal of embryonic and hematopoietic stem cells.	ZFX ZFY	2.19e-05	4	67	2	17448993
Pubmed	Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.	ZBTB49 ZBTB17	3.64e-05	5	67	2	25245946
Pubmed	Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.	ZFX ZFY	3.64e-05	5	67	2	25164012
Pubmed	Chromosome mapping and expression of a putative testis-determining gene in mouse.	ZFX ZFY	3.64e-05	5	67	2	2563174
Pubmed	MSG1 (melanocyte-specific gene 1): mapping to chromosome Xq13.1, genomic organization, and promoter analysis.	ZFX ZFY	3.64e-05	5	67	2	9721210
Pubmed	Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.	ZFX ZFY	3.64e-05	5	67	2	7681608
Pubmed	ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome.	ADAMTS9 ADAMTS20	3.64e-05	5	67	2	31600785
Pubmed	Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily.	ZFX ZFY	5.46e-05	6	67	2	7821804
Pubmed	Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits.	GRIK3 GRIN2B	5.46e-05	6	67	2	18922769
Pubmed	Histone methyltransferase SETDB1 promotes cells proliferation and migration by interacting withTiam1 in hepatocellular carcinoma.	TIAM1 ZKSCAN4	7.63e-05	7	67	2	29739365
Pubmed	An evaluation of the inactive mouse X chromosome in somatic cell hybrids.	ZFX ZFY	7.63e-05	7	67	2	8460399
Pubmed	Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.	ZFX ZFY	7.63e-05	7	67	2	8378320
Pubmed	Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.	ZFX ZFY	7.63e-05	7	67	2	7928394
Pubmed	The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.	ZFX ZFY	7.63e-05	7	67	2	9588208
Pubmed	Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.	ZFX ZFY	7.63e-05	7	67	2	9196009
Pubmed	Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.	ZFX ZFY	1.02e-04	8	67	2	2034279
Pubmed	The secreted metalloprotease ADAMTS20 is required for melanoblast survival.	ADAMTS9 ADAMTS20	1.02e-04	8	67	2	18454205
Pubmed	Genetic mapping in the region of the mouse X-inactivation center.	ZFX ZFY	1.02e-04	8	67	2	1974879
Pubmed	Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.	ADAMTS9 ADAMTS20	1.02e-04	8	67	2	21041365
Pubmed	Transmembrane topology of the glutamate receptor subunit GluR6.	GRIK3 GRIN2B	1.02e-04	8	67	2	8163463
Pubmed	High-density molecular map of the central span of the mouse X chromosome.	ZFX ZFY	1.02e-04	8	67	2	1675191
Pubmed	exma: an X-linked insertional mutation that disrupts forebrain and eye development.	ZFX ZFY	1.30e-04	9	67	2	11956759
Pubmed	Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.	ZFX ZFY	1.30e-04	9	67	2	7590750
Pubmed	Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.	ZFX ZFY	1.30e-04	9	67	2	7874112
Pubmed	The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter.	ZFX ZFY	1.30e-04	9	67	2	9300697
Pubmed	Praja1, a novel gene encoding a RING-H2 motif in mouse development.	ZFX ZFY	1.30e-04	9	67	2	9393880
Pubmed	Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.	ZFX ZFY	1.63e-04	10	67	2	2055107
Pubmed	Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development.	IHH PRDM2	1.63e-04	10	67	2	23333759
Pubmed	Mapping of the phosphorylase kinase alpha subunit gene on the mouse X chromosome.	ZFX ZFY	1.63e-04	10	67	2	1973380
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DMXL2 TIAM1 ADAMTS9 SLF2 VPS39 NBEA GRIN2B EXTL3 REV3L ZNF331	1.67e-04	1285	67	10	35914814
Pubmed	Characterization of a murine gene expressed from the inactive X chromosome.	ZFX ZFY	1.99e-04	11	67	2	2034278
Pubmed	Hydrocephalus in mouse B3glct mutants is likely caused by defects in multiple B3GLCT substrates in ependymal cells and subcommissural organ.	ADAMTS9 ADAMTS20	1.99e-04	11	67	2	33909046
Pubmed	Zinc finger protein genes in the mouse genome.	ZFX ZFY	2.38e-04	12	67	2	1797234
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS9 ADAMTS20	2.38e-04	12	67	2	25770910
Pubmed	The construction of human somatic cell hybrids containing portions of the mouse X chromosome and their use to generate DNA probes via interspersed repetitive sequence polymerase chain reaction.	ZFX ZFY	2.38e-04	12	67	2	1916827
Pubmed	An investigation into the human serum "interactome".	RLF TIAM1 DGKG CFB	2.77e-04	162	67	4	15174051
Pubmed	The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.	ZFX ZFY	2.81e-04	13	67	2	7805729
Pubmed	Localization of murine X and autosomal sequences homologous to the human Y located testis-determining region.	ZFX ZFY	2.81e-04	13	67	2	2721933
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	ZFX ZFY	2.81e-04	13	67	2	1740345
Pubmed	Mapping anti-müllerian hormone (Amh) and related sequences in the mouse: identification of a new region of homology between MMU10 and HSA19p.	AOX1 ZFY	2.81e-04	13	67	2	1685136
Pubmed	Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.	GRIK3 GRIN2B	2.81e-04	13	67	2	20859245
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	ZFX ZFY	2.81e-04	13	67	2	1772416
Pubmed	Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.	ZFX ZFY	3.28e-04	14	67	2	8432533
Pubmed	Molecular phylogenetics and the origins of placental mammals.	ZFX ZFY	3.78e-04	15	67	2	11214319
Pubmed	Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.	ZFX ZFY	3.78e-04	15	67	2	11353388
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	ZFX ZFY	3.78e-04	15	67	2	14762062
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DMXL2 ADAMTS9 ARID2 CEP135 ANKRD26 ZNF407	3.78e-04	493	67	6	15368895
Pubmed	Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.	ZFX ZFY	4.88e-04	17	67	2	19571810
Pubmed	Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.	ADAMTS9 ADAMTS20	4.88e-04	17	67	2	22183742
Pubmed	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.	ZNF131 ZBTB17	4.88e-04	17	67	2	7557990
Pubmed	Local protease signaling contributes to neural tube closure in the mouse embryo.	PRSS8 CFB	6.79e-04	20	67	2	20152175
Pubmed	ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.	ADAMTS9 ADAMTS20	6.79e-04	20	67	2	19922873
Pubmed	The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.	PRKCQ GRIN2B	7.50e-04	21	67	2	22114277
Pubmed	Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.	CRACR2A DDX60L	7.50e-04	21	67	2	20708005
Pubmed	Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.	ADAMTS9 ADAMTS20	9.01e-04	23	67	2	30814516
Pubmed	ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.	ADAMTS9 ADAMTS20	9.01e-04	23	67	2	26027930
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF93 ZNF131 ZBTB17 MTF1 ARID2 ZNF689 ZKSCAN4	9.24e-04	808	67	7	20412781
Pubmed	Glutamate can act as a signaling molecule in mouse preimplantation embryos†.	GRIK3 GRIN2B	9.82e-04	24	67	2	35746896
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	ADAMTS9 ADAMTS20	1.07e-03	25	67	2	29475039
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RLF ZNF131 ZNF776 ARID2 ZKSCAN4 PRDM2	1.13e-03	608	67	6	36089195
Pubmed	Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.	ZFX ZFY	1.15e-03	26	67	2	10920247
Pubmed	Gene knockouts that cause female infertility: search for novel contraceptive targets.	ZFX ZFY	1.34e-03	28	67	2	15970507
Pubmed	Interactomes of SARS-CoV-2 and human coronaviruses reveal host factors potentially affecting pathogenesis.	VPS39 G3BP2	1.34e-03	28	67	2	34232536
Pubmed	Seven new loci associated with age-related macular degeneration.	ADAMTS9 CFB	1.44e-03	29	67	2	23455636
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	INTS13 ARID2 G3BP2 SLU7 NBEA REV3L	1.44e-03	638	67	6	31182584
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	ZNF93 INTS13 ZNF74 OSBP2 ZNF658B	1.79e-03	451	67	5	36168627
Pubmed	Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk.	ADAMTS9 PRKCQ	1.86e-03	33	67	2	20203524
Interaction	TRIM39 interactions	ZNF776 ZNF658 ZNF689 ZNF620 ZKSCAN4 ZNF331	1.58e-06	108	67	6	int:TRIM39
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZNF93 ZNF131 ZBTB49 ZNF776 ZNF547 ZBTB17 ZNF658 ZNF41 ZNF689 ZNF620 ZNF74 ZNF407 ZKSCAN4 ZFX ZFY ZNF331	2.49e-12	718	49	17	28
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS9 ADAMTS20	1.19e-03	19	49	2	50
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CHRNA6 GALM TIAM1 NEK10 PRKCQ	9.70e-06	189	67	5	9f6f6fe6e47f5c5fd48aab47a775f7bdd16de19c
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TIAM1 AOX1 DGKG GRIK3 PRKCQ	1.27e-05	200	67	5	f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TIAM1 AOX1 DGKG GRIK3 PRKCQ	1.27e-05	200	67	5	70a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TIAM1 AOX1 DGKG GRIK3 PRKCQ	1.27e-05	200	67	5	1639982d9d994918f7912d12d9d7cfcbc9da4145
Disease	Dermatologic disorders	PRSS8 ZNF658 TRAPPC10 ZNF331	2.32e-05	75	65	4	C0037274
Disease	guilt measurement	GRIK3 ZKSCAN4	3.53e-03	40	65	2	EFO_0009595

Protein segments in the cluster

Peptide	Gene	Start	Entry
SFITHLQDKHCSKDA	ARID2	1681	Q68CP9
CTALHHDKHETKAEN	CRACR2A	291	Q9BSW2
ACINATKDSHHTLLH	DMXL2	566	Q8TDJ6
SHSHEEEKDLSHKNS	ANKRD26	901	Q9UPS8
KSDHSVVSDKECDHL	ADAMTS20	876	P59510
SALEDLHSKHHCSTL	AOX1	551	Q06278
LFDFLHAKDHCVAHK	UQCRHL	71	A0A096LP55
HKDAHVDFLKSGDSH	INTS13	286	Q9NVM9
HKSLTDVALEHHEEC	PDGFC	321	Q9NRA1
HCFTVDDKEHSIKVS	CFB	526	P00751
QAKVHHVKCHEFTAT	PRKCQ	151	Q04759
HQHTDDKIFKIHTHC	KIAA0825	716	Q8IV33
EKTETKSHPHTECHS	DDX60L	1131	Q5H9U9
CHHELAVLSHETFEK	NEK10	826	Q6ZWH5
FSEAKKLCSKHDHSA	LY75	1556	O60449
HHLLDKAVHCTSSVE	OSBP2	561	Q969R2
DHVHEKNKKFDHESS	PPIG	731	Q13427
RDKEFHSHLTSHEKD	CEP135	1041	Q66GS9
TSETFAATCKKLHDH	DGKG	621	P49619
SKEKHFCARVHHAAS	GALM	251	Q96C23
HLKECFHCHKSNELA	CHRNA6	391	Q15825
HACDTSEHKNRHSKD	ADAMTS9	221	Q9P2N4
SECHTKIRHVDAHAT	G3BP2	71	Q9UN86
LSHDDSHFHERHKCI	EXTL3	866	O43909
SLIVVDECHHTHKDT	DHX58	126	Q96C10
DCFQSKHKSASKPHH	CCDC168	6986	Q8NDH2
HKKHATDFATENLCS	HELQ	136	Q8TDG4
HVCQSSSKFHLHENK	CCDC144A	386	A2RUR9
IHFHDSFEATKKACD	GRIK3	86	Q13003
ESKAHVHCSVKSEHS	IHH	181	Q14623
HCSDSEGKEFKESHS	PRDM2	856	Q13029
QKLKEAHDALHHFSC	SKOR1	931	P84550
CGKAFAASHHLKTHV	MTF1	266	Q14872
FKFKSESDIHLAEHH	NBEA	416	Q8NFP9
CDHLISAAKHRDHVT	NBEA	2021	Q8NFP9
DIHAKCELAFLHTSH	SELENBP1	126	Q13228
CSGHSTESTKHKEHK	SLF2	511	Q8IX21
LSAAHCFPSEHHKEA	PRSS8	81	Q16651
HHFEDSKTLHSVEEK	CCDC110	131	Q8TBZ0
ECGKAFHLSTHLTTH	ZNF93	541	P35789
GCFTEKHIHKHAETK	USP51	256	Q70EK9
KILSGHEHAVSTCHF	WDR88	96	Q6ZMY6
CATAVARHHHKEDTL	TIAM1	546	Q13009
FLSHDNQKCDEDKHH	REV3L	1696	O60673
SKALAKHCSDSHNLD	RLF	1376	Q13129
FHRHEKCHTGEKSFE	ZNF620	211	Q6ZNG0
THQRHHKENSFECKD	ZNF331	121	Q9NQX6
CSKYEEDVKIHNHTH	SLU7	416	O95391
SHDKQDKIHSCLEHL	PREX2	1151	Q70Z35
LSCKHIETSAALHHN	REM2	251	Q8IYK8
CEKTFSHKTHLSVHQ	ZNF658	551	Q5TYW1
HRSTHTEEKLHACDD	ZNF689	391	Q96CS4
HLETHDTDKEHKCPH	ZBTB17	436	Q13105
SCSLLEHHKIHTGEK	ZKSCAN4	416	Q969J2
GANSCEHDHYEKHLS	ZNF41	281	P51814
SIHQKTHTGEKHYEC	ZNF41	441	P51814
CGKAFSHKHKLSDHQ	ZNF547	161	Q8IVP9
KTHQCLHCDHKSSNS	ZFX	631	P17010
AFTCHSSLTVHEKIH	ZNF74	396	Q16587
HLCEEKAKSYSNSHE	TTC23	46	Q5W5X9
EHKKTHTADKVFTCD	ZBTB49	496	Q6ZSB9
DGHHFKAHKAVLAAC	ZNF131	41	P52739
HCEFSAHSSASLELH	ZNF407	1021	Q9C0G0
ASDHHLTEEERKHFC	TRAPPC10	546	P48553
SKTHQCLHCDHKSSN	ZFY	626	P08048
HCHIEESEHVLKKAH	VPS39	486	Q96JC1
CEKTFSHKTHLSVHQ	ZNF658B	311	Q4V348
ECDKSFSHKHSLVDH	ZNF776	296	Q68DI1
KDAHEKDDFHHLSVV	GRIN2B	51	Q13224