Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainRhs_assc_core

TENM4 TENM2

3.61e-063212IPR022385
DomainTox-GHH_dom

TENM4 TENM2

7.21e-064212IPR028916
DomainTENEURIN_N

TENM4 TENM2

7.21e-064212PS51361
DomainTen_N

TENM4 TENM2

7.21e-064212IPR009471
DomainTox-GHH

TENM4 TENM2

7.21e-064212PF15636
DomainTen_N

TENM4 TENM2

7.21e-064212PF06484
DomainYD

TENM4 TENM2

1.20e-055212IPR006530
DomainCUT_dom

CUX2 CUX1

2.52e-057212IPR003350
DomainCUT

CUX2 CUX1

2.52e-057212PF02376
DomainCUT

CUX2 CUX1

2.52e-057212SM01109
DomainCUT

CUX2 CUX1

2.52e-057212PS51042
DomainNHL

TENM4 TENM2

9.32e-0513212PS51125
DomainCarboxyPept-like_regulatory

TENM4 TENM2

1.62e-0417212IPR008969
DomainCupredoxin

TMED6 PKHD1L1

2.74e-0422212IPR008972
Domain-

CUX2 CUX1

4.16e-04272121.10.260.40
DomainLambda_DNA-bd_dom

CUX2 CUX1

4.80e-0429212IPR010982
Domain-

TENM4 TENM2

8.70e-04392122.120.10.30
Domain6-blade_b-propeller_TolB-like

TENM4 TENM2

1.21e-0346212IPR011042
DomainHomeobox_CS

CUX2 CUX1

1.83e-02186212IPR017970
Pubmed

Cux1 and Cux2 selectively target basal and apical dendritic compartments of layer II-III cortical neurons.

CUX2 CUX1

5.80e-07227225059644
Pubmed

Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons.

CUX2 CUX1

5.80e-07227218327765
Pubmed

A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.

CUX2 CUX1

5.80e-0722728879483
Pubmed

CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate.

CUX2 CUX1

5.80e-07227235581205
Pubmed

Cux1 Enables Interhemispheric Connections of Layer II/III Neurons by Regulating Kv1-Dependent Firing.

CUX2 CUX1

5.80e-07227226804994
Pubmed

Expression of a cut-related homeobox gene in developing and polycystic mouse kidney.

CUX2 CUX1

5.80e-0722728840273
Pubmed

The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.

TRBV6-6 TRBV6-3 TRBV6-2 TRBV6-1

8.74e-07952748650574
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM4 TENM2

3.48e-06427212000766
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM4 TENM2

3.48e-06427210225957
Pubmed

Biochemical characterization of the mammalian Cux2 protein.

CUX2 CUX1

3.48e-06427215656993
Pubmed

Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex.

CUX2 CUX1

3.48e-06427220510857
Pubmed

Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut.

CUX2 CUX1

5.80e-0652728798433
Pubmed

The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype.

CUX2 CUX1

5.80e-0652727910552
Pubmed

Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex.

CUX2 CUX1

8.69e-06627215452856
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

TENM4 TENM2

1.22e-05727210625539
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM4 TENM2

1.22e-05727212915301
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TENM2

1.62e-05827210331952
Pubmed

IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons.

CUX2 CUX1

1.62e-05827221104742
Pubmed

Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.

CUX2 CUX1

2.08e-05927234235142
Pubmed

Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.

TOP2B CUX1

2.08e-05927231541646
Pubmed

Cux-2 controls the proliferation of neuronal intermediate precursors of the cortical subventricular zone.

CUX2 CUX1

2.60e-051027218033766
Pubmed

IRX3/5 regulate mitotic chromatid segregation and limb bud shape.

CUX2 CUX1

2.60e-051027232907847
Pubmed

Glycine receptors control the generation of projection neurons in the developing cerebral cortex.

CUX2 CUX1

2.60e-051027224926615
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM4 TENM2

2.60e-051027238713721
Pubmed

The genomic structure of human V beta 6 T cell antigen receptor genes.

TRBV6-2 TRBV6-1

3.18e-05112721660526
Pubmed

Molecular interaction between projection neuron precursors and invading interneurons via stromal-derived factor 1 (CXCL12)/CXCR4 signaling in the cortical subventricular zone/intermediate zone.

CUX2 CUX1

5.25e-051427217182777
Pubmed

COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression.

CUX2 CUX1

5.25e-051427221965613
Pubmed

Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development.

CUX2 CUX1

6.92e-051627235379703
Pubmed

Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex.

CUX2 CUX1

6.92e-051627226235615
Pubmed

Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex.

CUX2 CUX1

7.84e-051727221315259
Pubmed

PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.

CUX2 CUX1

9.84e-051927233597191
Pubmed

Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools.

CUX2 CUX1

9.84e-051927221666133
Pubmed

Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus.

CUX2 CUX1

1.21e-042127224483844
Pubmed

The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain.

CUX2 CUX1

1.33e-042227220506362
Pubmed

Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination.

CUX2 CUX1

1.45e-042327222090492
Pubmed

DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.

CUX2 CUX1

1.45e-042327230329130
Pubmed

Multiple knockout mouse models reveal lincRNAs are required for life and brain development.

CUX2 CUX1

1.59e-042427224381249
Pubmed

MicroRNAs establish robustness and adaptability of a critical gene network to regulate progenitor fate decisions during cortical neurogenesis.

CUX2 CUX1

1.59e-042427224931612
Pubmed

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.

CUX2 CUX1

1.72e-042527228288114
Pubmed

Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion.

CUX2 CUX1

1.72e-042527239271675
Pubmed

AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex.

CUX2 CUX1

1.86e-042627219749747
Pubmed

Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons.

CUX2 CUX1

2.01e-042727222334647
Pubmed

Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

CUX2 CUX1

2.17e-042827223643363
Pubmed

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone.

CUX2 CUX1

2.17e-042827218794345
Pubmed

Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain.

CUX2 CUX1

2.49e-043027217470284
Pubmed

Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice.

CUX2 CUX1

2.84e-043227219571125
Pubmed

Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells.

CUX2 CUX1

3.21e-043427231569049
Pubmed

Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.

CUX2 CUX1

3.40e-043527222991445
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

ATP8B3 ADORA3 TENM4 HERPUD2 PKHD1L1

3.65e-0481427523251661
Pubmed

Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex.

CUX2 CUX1

4.01e-043827231080058
Pubmed

Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons.

CUX2 CUX1

4.90e-044227224997765
Pubmed

A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation.

CUX2 CUX1

6.95e-045027222365545
Pubmed

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.

TENM4 TENM2

7.23e-045127216919471
Cytoband7q34

TRBV6-6 TRBV6-3 TRBV6-2 TRBV6-1

2.78e-061672747q34
CytobandEnsembl 112 genes in cytogenetic band chr7q34

TRBV6-6 TRBV6-2 TRBV6-1

1.75e-04185273chr7q34
GeneFamilyT cell receptor beta locus at 7q34

TRBV6-6 TRBV6-3 TRBV6-2 TRBV6-1

1.45e-0687184372
GeneFamilyCUT class homeoboxes and pseudogenes

CUX2 CUX1

3.36e-059182527
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 TENM2 MAN1C1 CUX1

4.14e-0618127457994ff4ecffb15653aee00644d9f887f5e3461d
ToppCelldroplet-Fat-SCAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 TENM4 TENM2

1.21e-04160273fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCelldroplet-Fat-SCAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 TENM4 TENM2

1.21e-04160273759749f708c3a2b36692d42499f19aff937e592f
ToppCelldroplet-Fat-SCAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 TENM4 TENM2

1.21e-0416027367ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CUX2 TENM4 CUX1

1.28e-04163273431221a41d396b09170476179590eaf8a55266d8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CUX2 TENM4 CUX1

1.28e-041632731e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellMild-MAIT|World / Disease group and Cell class

MTMR7 HERPUD2 TRBV6-1

1.30e-0416427321dc02997dfae73cf70ce291661928526605dba1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CUX2 MAP3K4 TRBV6-2

1.38e-0416727383969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

TRPM4 CUX2 TENM4

1.38e-04167273bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 UPB1 MAN1C1

1.43e-041692737962165cab84af73d20b56eb70b1ed87c94025ef
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1GALT1C1 UPB1 HERPUD2

1.53e-04173273a042f78a4c69fcc6b5ca76e9bf01e34cee54c81c
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPB1 TENM4 MAN1C1

1.53e-04173273ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPB1 TENM4 MAN1C1

1.53e-0417327319a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1GALT1C1 UPB1 HERPUD2

1.53e-041732733c51e7bda1835c25915e50c801b0d643979971a3
ToppCellcritical-Myeloid-pDC|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CUX2 RPN2 PKHD1L1

1.53e-04173273e8508c3efbe0f0fae51484a5535d43103c810d4e
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

CUX2 UPB1 SLCO1B1

1.58e-041752737f74961436f88c0e380819095e6104489914d765
ToppCelldroplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 UPB1 MAN1C1

1.58e-0417527321bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

CUX2 UPB1 SLCO1B1

1.58e-04175273bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B3 TRBV6-3 TRBV6-1

1.61e-04176273ac83a6cd4bcbb9ca1fc02a9fbd9d9629ef1df8ca
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPM4 CUX2 CUX1

1.61e-04176273e788c7e0b2bfde31fddbf9e04d07140f8b964857
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPM4 CUX2 CUX1

1.66e-04178273e4e11e4940c911c17806200c25096928153c684d
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 UPB1 MAN1C1

1.66e-04178273742ee0cb8cb585a5e34bd5b20aebe9bb99756e0c
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 UPB1 MAN1C1

1.69e-04179273d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPB1 TENM4 MAN1C1

1.72e-0418027382965ed1b72a1873c24dd4553d39681596057316
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPB1 TENM4 MAN1C1

1.72e-04180273bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPB1 TENM4 MAN1C1

1.72e-04180273839defb40f7cfb2711e9025194de636533f51bcd
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUX2 TENM4 TENM2

1.77e-04182273b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUX2 TENM4 TENM2

1.77e-04182273cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 TENM2 CUX1

1.83e-041842736475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 TENM2 CUX1

1.83e-04184273658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 TENM2 CUX1

2.01e-041902731bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

C1GALT1C1 RPN2 PKHD1L1

2.01e-04190273f85cdd79eefd699ada7a91bf4997cc730a9b9846
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

C1GALT1C1 RPN2 PKHD1L1

2.04e-04191273fca19f2719806f3dc2dd2add7252ab1198548f4d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

C1GALT1C1 RPN2 PKHD1L1

2.04e-04191273208cd307826b5af89f8f10c0c915f90f80a25c6c
ToppCellfacs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPN2 MAN1C1 CUX1

2.08e-04192273ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

C1GALT1C1 RPN2 PKHD1L1

2.08e-04192273ec279980602292fc8ed6362edd36a5c772d59777
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 TENM2 CUX1

2.08e-0419227325460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

CUX2 TENM4 CUX1

2.11e-041932733b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

C1GALT1C1 RPN2 PKHD1L1

2.11e-0419327343ffa8ecc72bebcd204279db2bde98ae48d97f90
ToppCellsevere-Plasmablast|World / disease stage, cell group and cell class

C1GALT1C1 RPN2 PKHD1L1

2.14e-0419427349e8f90db571a89b8a26aef31fcacd66429fed11
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

C1GALT1C1 RPN2 PKHD1L1

2.14e-04194273297286c57d7ee6338d9cf77b27eb2809378ce15d
ToppCellsevere-Plasmablast|severe / disease stage, cell group and cell class

C1GALT1C1 RPN2 PKHD1L1

2.17e-04195273e11616ad568e50e4c720b50b0c071f484c31d16b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 TENM2 CUX1

2.17e-04195273787e95fb59c40bba784544b662fac37606ae1427
ToppCellMild/Remission-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

C1GALT1C1 RPN2 PKHD1L1

2.17e-0419527352bdd609253613b7db75dccbc1c01c05e8d73f79
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

CUX2 TENM4 CUX1

2.20e-041962739401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellMild/Remission-Plasmablast|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

C1GALT1C1 RPN2 PKHD1L1

2.20e-04196273dcf0a804a79a05454658498d1f87320c7e079219
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

XKR6 TENM4 TENM2

2.27e-041982738ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCelldroplet-Skin-nan-21m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 UPB1 TENM2

2.34e-0420027369295705fc614c2687f2b6c8e6aa0c6717841008
Drugrhenium sulfide

CUX2 CUX1

5.34e-064222CID000159414
Drugdimethylphenylphosphine

CUX2 CUX1

8.90e-065222CID000069597
Drugcovellite

CUX2 CUX1

1.87e-057222CID000014831
DrugAC1L85AO

SLCO1B1 TOP2B CUX1

3.44e-0566223CID000372705
DrugAC1O52TI

TOP2B CUX1

9.29e-0515222CID006426890
Drug5-iodouracil

SLCO1B1 CUX1

5.50e-0436222CID000069672
DrugLY 294002; Down 200; 10uM; HL60; HT_HG-U133A

ADORA3 CUX2 MAN1C1

7.37e-041862236198_DN
DrugZardaverine [101975-10-4]; Up 200; 15uM; PC3; HT_HG-U133A

UPB1 SLCO1B1 MAN1C1

7.48e-041872234209_UP
DrugATP,Gamma S

TRPM4 ADORA3 TOP2B

7.72e-04189223CID000002028
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; HL60; HT_HG-U133A

ADORA3 UPB1 CUX1

7.84e-041902231343_DN
DrugHomosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A

ADORA3 TENM4 MAN1C1

8.45e-041952234355_UP
DrugSulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

TRPM4 CUX2 MAN1C1

8.70e-041972235528_UP
DrugRitodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A

ADORA3 UPB1 MAN1C1

8.83e-041982235680_UP
DrugFolinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; HL60; HT_HG-U133A

UPB1 SLCO1B1 MAN1C1

8.83e-041982232579_DN
DrugCefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A

ADORA3 CUX2 TENM4

8.96e-041992232235_UP
DrugPrilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A

ADORA3 CUX2 SLCO1B1

8.96e-041992234284_UP
DrugGlyburide

TRPM4 SLCO1B1

1.43e-0358222ctd:D005905
DrugPyrrolizidine Alkaloids

SLCO1B1 TENM2

1.84e-0366222ctd:D011763
Diseasehematologic cancer (implicated_via_orthology)

CUX2 CUX1

4.12e-0513222DOID:2531 (implicated_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

XKR6 TMED6 SLCO1B1

1.96e-04153223EFO_0004611, EFO_0020944
Diseaseresponse to simvastatin, myopathy

XKR6 SLCO1B1

4.28e-0441222EFO_0004145, GO_1903491
DiseaseTourette syndrome

TENM4 TENM2

6.36e-0450222EFO_0004895
Diseaseblood copper measurement

CUX2 MAN1C1

6.36e-0450222EFO_0007578
Diseasecancer (implicated_via_orthology)

CUX2 TOP2B CUX1

1.00e-03268223DOID:162 (implicated_via_orthology)
DiseaseCleft palate, cleft lip

CUX2 TENM4 TENM2

1.13e-03279223EFO_0003959, HP_0000175
DiseaseEndometrial Carcinoma

CUX1 MAP3K4

1.31e-0372222C0476089
Diseasefree androgen index

CUX2 SLCO1B1 CUX1

2.60e-03374223EFO_0007005
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

XKR6 TENM4 TENM2 CUX1

2.67e-03801224EFO_0003888, EFO_0007052, MONDO_0002491

Protein segments in the cluster

PeptideGeneStartEntry
MNHNYMYWYRQDPGM

TRBV6-6

46

A0A0A6YYG2
VMRMDYMVYFSFLTW

ADORA3

171

P0DMS8
FYKSMASMMVQVWFA

ATP8B3

1001

O60423
MAANVGSMFQYWKRF

CUX2

1

O14529
NDMWLMMRKAYKYAF

C1GALT1C1

116

Q96EU7
TPCNFMYKFWSGMYN

MTMR7

491

Q9Y216
MAANVGSMFQYWKRF

CUX1

1

Q13948
NDVWNFKMTGRYEMY

UPB1

351

Q9UBR1
MMQFAWQSYKRYAMG

MAN1C1

181

Q9NR34
MLWWQQMYAHQYYMQ

HERPUD2

191

Q9BSE4
KMLMVYFDYMRSWIQ

MAP3K4

696

Q9Y6R4
EYKHSFKQTWMNNMM

TOP2B

206

Q02880
MMYSGEMCYWGSKYC

RIMOC1

211

A6NDU8
MNKWRLYYQVLNFGM

SEC11B

1

P0C7V7
KEVQYEMFRSLMYWM

TENM2

2161

Q9NT68
EMFRSLMYWMTVQYD

TENM2

2166

Q9NT68
SGSYMWIYVFMGNML

SLCO1B1

166

Q9Y6L6
MNHEYMYWYRQDPGM

TRBV6-2

46

A0A0J9YXY3
FYWAMMYEYADVNML

XKR6

276

Q5GH73
LQPNMYGMMEQWDKY

MKRN2OS

116

H3BPM6
MNHEYMYWYRQDPGM

TRBV6-3

46

P0DPF7
MLGLMYVYWTQLNMF

RPN2

586

P04844
MWRYYNFARMRKMAD

TMED6

176

Q8WW62
SLMYWMTVQYDNMGR

TENM4

2161

Q6N022
WQSYQCFGMEYAMMV

PKHD1L1

3756

Q86WI1
MNHNSMYWYRQDPGM

TRBV6-1

46

A0A0K0K1D8
MEWFNNYKRSLATYM

GINS1

111

Q14691
RAQMAMYFWEMGSNA

TRPM4

571

Q8TD43