Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZBTB9 ZBTB40 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZNF451 ZBTB14 ZFX ZFY ZNF404 ZNF516 ZNF304	8.56e-12	1412	25	15	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZBTB9 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 TOP1 ZEB2 ZBTB14 ZFX ZFY ZNF404 ZNF516 ZNF304	2.41e-10	1459	25	14	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZBTB9 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 TOP1 ZEB2 ZBTB14 ZFX ZFY ZNF516 ZNF304	5.15e-10	1244	25	13	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZBTB9 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 TOP1 ZEB2 ZBTB14 ZFX ZFY ZNF516 ZNF304	6.71e-10	1271	25	13	GO:0000987
GeneOntologyMolecularFunction	chromatin binding	ZEB1 PRDM15 ATF2 TOP1 ZFX ZFY ASH1L ZNF304	2.09e-06	739	25	8	GO:0003682
GeneOntologyMolecularFunction	chromatin insulator sequence binding	ZFX ZFY	3.15e-05	7	25	2	GO:0043035
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF536 ZEB1 ZNF148 ZEB2 ZBTB14	4.18e-05	320	25	5	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF536 ZEB1 ZNF148 ZEB2 ZBTB14	4.57e-05	326	25	5	GO:0001217
GeneOntologyMolecularFunction	promoter-specific chromatin binding	PRDM15 ATF2 ZNF304	1.49e-04	83	25	3	GO:1990841
GeneOntologyMolecularFunction	N-acyltransferase activity	TLCD3B ATF2 BRPF1	2.74e-04	102	25	3	GO:0016410
GeneOntologyMolecularFunction	histone H4 acetyltransferase activity	ATF2 BRPF1	3.75e-04	23	25	2	GO:0010485
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	PRDM15 ATF2 ZEB2 ZFX ZFY	5.68e-04	560	25	5	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	PRDM15 ATF2 ZEB2 ZFX ZFY	5.97e-04	566	25	5	GO:0001216
GeneOntologyMolecularFunction	chromatin DNA binding	TOP1 ZFX ZFY	1.15e-03	167	25	3	GO:0031490
GeneOntologyMolecularFunction	histone acetyltransferase activity	ATF2 BRPF1	1.85e-03	51	25	2	GO:0004402
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	ATF2 BRPF1	2.15e-03	55	25	2	GO:0061733
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	ATF2 BRPF1	2.55e-03	60	25	2	GO:0034212
GeneOntologyMolecularFunction	histone modifying activity	ATF2 BRPF1 ASH1L	2.84e-03	229	25	3	GO:0140993
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	TLCD3B ATF2 BRPF1	3.17e-03	238	25	3	GO:0016747
GeneOntologyMolecularFunction	N-acetyltransferase activity	ATF2 BRPF1	4.26e-03	78	25	2	GO:0008080
GeneOntologyMolecularFunction	acetyltransferase activity	ATF2 BRPF1	7.45e-03	104	25	2	GO:0016407
GeneOntologyMolecularFunction	acyltransferase activity	TLCD3B ATF2 ZNF451 BRPF1	1.49e-02	775	25	4	GO:0016746
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ZNF407 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZFX ZFY ASH1L ZNF304	2.40e-06	1390	25	10	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	ZNF536 ZEB1 ZNF148 ATF2 ZEB2 ZNF451 ZBTB14 ZNF304	2.23e-05	1053	25	8	GO:0000122
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	ZNF536 ZEB1 ZNF148 ATF2 ZEB2 ZNF451 ZBTB14 ZNF304	1.67e-04	1399	25	8	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	ZNF536 ZEB1 ZNF148 ATF2 ZEB2 ZNF451 ZBTB14 ZNF304	1.79e-04	1413	25	8	GO:1902679
GeneOntologyBiologicalProcess	chromatin remodeling	ATF2 TOP1 BRPF1 ZFY ASH1L ZNF304	2.08e-04	741	25	6	GO:0006338
GeneOntologyBiologicalProcess	parental behavior	ZFX ZFY	2.92e-04	21	25	2	GO:0060746
GeneOntologyBiologicalProcess	post-embryonic development	ZFX ZFY ASH1L	5.68e-04	135	25	3	GO:0009791
GeneOntologyBiologicalProcess	chromatin organization	ATF2 TOP1 BRPF1 ZFY ASH1L ZNF304	5.75e-04	896	25	6	GO:0006325
Domain	ZINC_FINGER_C2H2_2	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZNF451 ZBTB14 BRPF1 ZFX ZFY ZNF404 ZNF516 ZNF304	7.12e-19	775	24	17	PS50157
Domain	ZINC_FINGER_C2H2_1	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZNF451 ZBTB14 BRPF1 ZFX ZFY ZNF404 ZNF516 ZNF304	7.44e-19	777	24	17	PS00028
Domain	Znf_C2H2-like	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZNF451 ZBTB14 BRPF1 ZFX ZFY ZNF404 ZNF516 ZNF304	1.12e-18	796	24	17	IPR015880
Domain	Znf_C2H2	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZNF451 ZBTB14 BRPF1 ZFX ZFY ZNF404 ZNF516 ZNF304	1.35e-18	805	24	17	IPR007087
Domain	ZnF_C2H2	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZNF451 ZBTB14 BRPF1 ZFX ZFY ZNF404 ZNF516 ZNF304	1.44e-18	808	24	17	SM00355
Domain	-	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZBTB14 ZFX ZFY ZNF404 ZNF516 ZNF304	2.12e-16	679	24	15	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ATF2 ZEB2 ZBTB14 ZFX ZFY ZNF404 ZNF516 ZNF304	2.94e-16	694	24	15	IPR013087
Domain	zf-C2H2	ZBTB9 ZBTB40 ZNF407 ZNF536 ZNF148 PRDM15 ATF2 ZNF451 ZBTB14 ZFX ZFY ZNF404 ZNF516 ZNF304	1.15e-14	693	24	14	PF00096
Domain	Zfx_Zfy_act	ZFX ZFY	4.74e-06	3	24	2	PF04704
Domain	Transcrp_activ_Zfx/Zfy-dom	ZFX ZFY	4.74e-06	3	24	2	IPR006794
Domain	Di19_Zn_binding_dom	ZEB1 ZEB2	3.31e-05	7	24	2	IPR008598
Domain	zf-Di19	ZEB1 ZEB2	3.31e-05	7	24	2	PF05605
Domain	BTB	ZBTB9 ZBTB40 ZBTB14	6.13e-04	131	24	3	PF00651
Domain	BROMODOMAIN_1	BRPF1 ASH1L	1.03e-03	37	24	2	PS00633
Domain	Bromodomain	BRPF1 ASH1L	1.08e-03	38	24	2	PF00439
Domain	BTB	ZBTB9 ZBTB40 ZBTB14	1.09e-03	160	24	3	PS50097
Domain	BROMODOMAIN_2	BRPF1 ASH1L	1.26e-03	41	24	2	PS50014
Domain	BROMO	BRPF1 ASH1L	1.32e-03	42	24	2	SM00297
Domain	Bromodomain	BRPF1 ASH1L	1.32e-03	42	24	2	IPR001487
Domain	-	BRPF1 ASH1L	1.32e-03	42	24	2	1.20.920.10
Domain	BTB	ZBTB9 ZBTB40 ZBTB14	1.54e-03	180	24	3	SM00225
Domain	SET	PRDM15 ASH1L	1.58e-03	46	24	2	SM00317
Domain	BTB/POZ_dom	ZBTB9 ZBTB40 ZBTB14	1.66e-03	185	24	3	IPR000210
Domain	SKP1/BTB/POZ	ZBTB9 ZBTB40 ZBTB14	1.77e-03	189	24	3	IPR011333
Domain	SET_dom	PRDM15 ASH1L	1.87e-03	50	24	2	IPR001214
Domain	SET	PRDM15 ASH1L	1.87e-03	50	24	2	PS50280
Domain	Zinc_finger_PHD-type_CS	BRPF1 ASH1L	3.13e-03	65	24	2	IPR019786
Domain	Znf_PHD-finger	BRPF1 ASH1L	4.59e-03	79	24	2	IPR019787
Domain	PHD	BRPF1 ASH1L	5.79e-03	89	24	2	SM00249
Domain	Znf_PHD	BRPF1 ASH1L	6.04e-03	91	24	2	IPR001965
Domain	ZF_PHD_2	BRPF1 ASH1L	6.57e-03	95	24	2	PS50016
Domain	ZF_PHD_1	BRPF1 ASH1L	6.70e-03	96	24	2	PS01359
Domain	Znf_FYVE_PHD	BRPF1 ASH1L	1.52e-02	147	24	2	IPR011011
Domain	HOMEOBOX_1	ZEB1 ZEB2	3.66e-02	236	24	2	PS00027
Domain	HOX	ZEB1 ZEB2	3.68e-02	237	24	2	SM00389
Pubmed	The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).	ZBTB14 ZFX ZFY	3.28e-09	5	25	3	9244432
Pubmed	Interaction network of human early embryonic transcription factors.	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2 ZBTB14 ZNF516	4.13e-09	351	25	7	38297188
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZBTB9 ZBTB40 ZNF148 PRDM15 TOP1 ZEB2 ZNF451 BRPF1	6.94e-09	608	25	8	36089195
Pubmed	A census of human transcription factors: function, expression and evolution.	ZEB1 ZNF148 ATF2 ZEB2 ZNF451 ZBTB14 ZFX ZFY ASH1L	7.60e-09	908	25	9	19274049
Pubmed	Human transcription factor protein interaction networks.	ZBTB9 ZBTB40 ZNF536 ZEB1 ZNF148 TOP1 ZEB2 ZNF451 ZBTB14 ZNF516	2.47e-08	1429	25	10	35140242
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ZBTB9 ZNF407 ATF2 ZEB2 ZNF451 BRPF1 ZFY ASH1L	1.17e-07	877	25	8	20211142
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2 ZNF516	4.24e-07	418	25	6	34709266
Pubmed	The Zeb proteins δEF1 and Sip1 may have distinct functions in lens cells following cataract surgery.	ZEB1 ZEB2	4.96e-07	2	25	2	25082886
Pubmed	The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.	ZEB1 ZEB2	4.96e-07	2	25	2	37948583
Pubmed	ZEBs: Novel Players in Immune Cell Development and Function.	ZEB1 ZEB2	4.96e-07	2	25	2	30956067
Pubmed	The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.	ZEB1 ZEB2	4.96e-07	2	25	2	37819755
Pubmed	Comparison of human ZFY and ZFX transcripts.	ZFX ZFY	4.96e-07	2	25	2	2308929
Pubmed	Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.	ZEB1 ZEB2	4.96e-07	2	25	2	28416756
Pubmed	Mapping the human ZFX locus to Xp21.3 by in situ hybridization.	ZFX ZFY	4.96e-07	2	25	2	2497060
Pubmed	RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.	ZFX ZFY	4.96e-07	2	25	2	28251288
Pubmed	Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.	ZFX ZFY	4.96e-07	2	25	2	12716983
Pubmed	The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer.	ZEB1 ZEB2	4.96e-07	2	25	2	28133913
Pubmed	Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.	ZFX ZFY	4.96e-07	2	25	2	9126493
Pubmed	Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.	ZFX ZFY	4.96e-07	2	25	2	2041734
Pubmed	Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway.	ZEB1 ZEB2	4.96e-07	2	25	2	20025777
Pubmed	Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.	ZEB1 ZEB2	4.96e-07	2	25	2	20424117
Pubmed	Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.	ZFX ZFY	4.96e-07	2	25	2	8318216
Pubmed	Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.	ZFX ZFY	4.96e-07	2	25	2	2105457
Pubmed	Zfhx1a and Zfhx1b mRNAs have non-overlapping expression domains during chick and mouse midgestation limb development.	ZEB1 ZEB2	4.96e-07	2	25	2	12609600
Pubmed	Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.	ZFX ZFY	4.96e-07	2	25	2	19329779
Pubmed	Expression of miRNAs and ZEB1 and ZEB2 correlates with histopathological grade in papillary urothelial tumors of the urinary bladder.	ZEB1 ZEB2	4.96e-07	2	25	2	24306957
Pubmed	Circ_0000520 contributes to triple-negative breast cancer progression through mediating the miR-1296/ZFX axis.	ZFX ZFY	4.96e-07	2	25	2	34324278
Pubmed	Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner.	ZEB1 ZEB2	4.96e-07	2	25	2	20375168
Pubmed	Prognostic Significance of Zinc Finger E-Box-Binding Homeobox Family in Glioblastoma.	ZEB1 ZEB2	4.96e-07	2	25	2	29476046
Pubmed	Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer.	ZEB1 ZEB2	4.96e-07	2	25	2	22213144
Pubmed	Zfx mutation results in small animal size and reduced germ cell number in male and female mice.	ZFX ZFY	4.96e-07	2	25	2	9187153
Pubmed	TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.	ZEB1 ZEB2	4.96e-07	2	25	2	21747944
Pubmed	Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs.	ZFX ZFY	4.96e-07	2	25	2	1970799
Pubmed	Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.	ZFX ZFY	4.96e-07	2	25	2	8487630
Pubmed	Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development.	ZEB1 ZEB2	4.96e-07	2	25	2	16957952
Pubmed	[Expression of Zfx in mouse testicular spermatogenic cells].	ZFX ZFY	4.96e-07	2	25	2	38602753
Pubmed	Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.	ZEB1 ZEB2	4.96e-07	2	25	2	34550965
Pubmed	Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer.	ZEB1 ZEB2	4.96e-07	2	25	2	22892238
Pubmed	Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.	ZFX ZFY	4.96e-07	2	25	2	1691708
Pubmed	Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.	ZFX ZFY	4.96e-07	2	25	2	2265557
Pubmed	The structure of the Zfx gene on the mouse X chromosome.	ZFX ZFY	4.96e-07	2	25	2	8188262
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ZBTB40 ZEB1 ZNF148 ATF2 BRPF1 ZFX ZNF516	8.92e-07	774	25	7	15302935
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZEB1 ZNF148 ATF2 ZNF451 BRPF1 ZNF516 ASH1L	1.19e-06	808	25	7	20412781
Pubmed	The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins.	ZEB1 ZEB2	1.49e-06	3	25	2	26823172
Pubmed	Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype.	ZEB1 ZEB2	1.49e-06	3	25	2	23412770
Pubmed	A miRNA signature associated with human metastatic medullary thyroid carcinoma.	ZEB1 ZEB2	1.49e-06	3	25	2	24127332
Pubmed	A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.	ZEB1 ZEB2	1.49e-06	3	25	2	21890822
Pubmed	The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.	ZEB1 ZEB2	1.49e-06	3	25	2	18376396
Pubmed	TCF4 promotes colorectal cancer drug resistance and stemness via regulating ZEB1/ZEB2 expression.	ZEB1 ZEB2	1.49e-06	3	25	2	31933004
Pubmed	p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.	ZEB1 ZEB2	1.49e-06	3	25	2	21518799
Pubmed	The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.	ZEB1 ZEB2	1.49e-06	3	25	2	18411277
Pubmed	miR-139-5p suppresses cancer cell migration and invasion through targeting ZEB1 and ZEB2 in GBM.	ZEB1 ZEB2	1.49e-06	3	25	2	25833697
Pubmed	Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2.	ZEB1 ZEB2	1.49e-06	3	25	2	24968735
Pubmed	Src promotes EGF-induced epithelial-to-mesenchymal transition and migration in gastric cancer cells by upregulating ZEB1 and ZEB2 through AKT.	ZEB1 ZEB2	1.49e-06	3	25	2	29052277
Pubmed	Expression of miR-9 and miR-200c, ZEB1, ZEB2 and E-cadherin in Non-Small Cell Lung Cancers in Iran.	ZEB1 ZEB2	1.49e-06	3	25	2	31244281
Pubmed	YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.	ZFX ZFY	1.49e-06	3	25	2	8406471
Pubmed	Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.	ZFX ZFY	1.49e-06	3	25	2	2480529
Pubmed	miR-144-3p inhibited the growth, metastasis and epithelial-mesenchymal transition of colorectal adenocarcinoma by targeting ZEB1/2.	ZEB1 ZEB2	1.49e-06	3	25	2	34226299
Pubmed	miR-139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2.	ZEB1 ZEB2	1.49e-06	3	25	2	26022123
Pubmed	An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.	ZEB1 ZEB2	1.49e-06	3	25	2	21411626
Pubmed	BMP4 signaling mediates Zeb family in developing mouse tooth.	ZEB1 ZEB2	1.49e-06	3	25	2	22350174
Pubmed	X chromosome genes and premature ovarian failure.	ZFX ZFY	1.49e-06	3	25	2	11299520
Pubmed	Genetic dissection of mammalian fertility pathways.	ZFX ZFY	1.49e-06	3	25	2	12479614
Pubmed	Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta.	ZEB1 ZEB2	1.49e-06	3	25	2	17615296
Pubmed	Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2.	ZEB1 ZEB2	1.49e-06	3	25	2	24165969
Pubmed	Isolation of monochromosomal hybrids for mouse chromosomes 3, 6, 10, 12, 14, and 18.	ZFX ZFY	1.49e-06	3	25	2	9060403
Pubmed	miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2.	ZEB1 ZEB2	1.49e-06	3	25	2	26556542
Pubmed	Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling.	ZFX ZFY	1.49e-06	3	25	2	38310188
Pubmed	Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.	ZFX ZFY	1.49e-06	3	25	2	32406922
Pubmed	miR-200c inhibits TGF-β-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer.	ZEB1 ZEB2	1.49e-06	3	25	2	29302045
Pubmed	Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.	ZEB1 APCDD1 ZEB2	1.60e-06	32	25	3	27806288
Pubmed	ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.	ZFX ZFY	2.97e-06	4	25	2	24485662
Pubmed	Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression.	ZEB1 ZEB2	2.97e-06	4	25	2	25301070
Pubmed	Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells.	ZEB1 ZEB2	2.97e-06	4	25	2	28247944
Pubmed	Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants.	ZEB1 ZEB2	2.97e-06	4	25	2	16598713
Pubmed	miR-200b regulates cell migration via Zeb family during mouse palate development.	ZEB1 ZEB2	2.97e-06	4	25	2	22261924
Pubmed	MiR-525-5p Repressed Metastasis and Anoikis Resistance in Cervical Cancer via Blocking UBE2C/ZEB1/2 Signal Axis.	ZEB1 ZEB2	2.97e-06	4	25	2	31679088
Pubmed	MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.	ZEB1 ZEB2	2.97e-06	4	25	2	17360662
Pubmed	miR-200b/c attenuates lipopolysaccharide-induced early pulmonary fibrosis by targeting ZEB1/2 via p38 MAPK and TGF-β/smad3 signaling pathways.	ZEB1 ZEB2	2.97e-06	4	25	2	29200203
Pubmed	miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.	ZEB1 ZEB2	2.97e-06	4	25	2	21079000
Pubmed	The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung.	ZEB1 ZEB2	2.97e-06	4	25	2	27215389
Pubmed	Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.	ZEB1 ZEB2	2.97e-06	4	25	2	23381389
Pubmed	Zfx controls the self-renewal of embryonic and hematopoietic stem cells.	ZFX ZFY	2.97e-06	4	25	2	17448993
Pubmed	Chromosome mapping and expression of a putative testis-determining gene in mouse.	ZFX ZFY	4.95e-06	5	25	2	2563174
Pubmed	MSG1 (melanocyte-specific gene 1): mapping to chromosome Xq13.1, genomic organization, and promoter analysis.	ZFX ZFY	4.95e-06	5	25	2	9721210
Pubmed	A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition.	ZEB1 ZEB2	4.95e-06	5	25	2	18829540
Pubmed	Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.	ZFX ZFY	4.95e-06	5	25	2	7681608
Pubmed	ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.	ZEB1 ZEB2	4.95e-06	5	25	2	29449309
Pubmed	Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins.	ZEB1 ZEB2	4.95e-06	5	25	2	12743039
Pubmed	Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway.	ZEB1 ZEB2	4.95e-06	5	25	2	12743038
Pubmed	Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.	ZFX ZFY	4.95e-06	5	25	2	25164012
Pubmed	A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression.	ZEB1 ZEB2	4.95e-06	5	25	2	19651985
Pubmed	Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily.	ZFX ZFY	7.43e-06	6	25	2	7821804
Pubmed	miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5.	ZEB1 ZEB2	7.43e-06	6	25	2	22685266
Pubmed	Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.	ZEB1 ZEB2	7.43e-06	6	25	2	12161443
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF536 ATF2 ZBTB14 BRPF1 ZFX ZFY	8.94e-06	709	25	6	22988430
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZBTB9 ZBTB40 ZNF148 ATF2 TOP1 ZEB2 ZNF516	9.22e-06	1103	25	7	34189442
Pubmed	An evaluation of the inactive mouse X chromosome in somatic cell hybrids.	ZFX ZFY	1.04e-05	7	25	2	8460399
Pubmed	Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.	ZFX ZFY	1.04e-05	7	25	2	8378320
Pubmed	Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.	ZFX ZFY	1.04e-05	7	25	2	7928394
Interaction	KLF12 interactions	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2 ZBTB14 ZNF516	2.85e-09	194	25	7	int:KLF12
Interaction	KLF3 interactions	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2 ZBTB14 ZNF516	8.75e-09	228	25	7	int:KLF3
Interaction	TEAD1 interactions	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2 ZNF516	6.29e-08	176	25	6	int:TEAD1
Interaction	H3-3A interactions	ZBTB9 ZBTB40 ZNF148 PRDM15 TOP1 ZEB2 ZNF451 BRPF1 ASH1L	1.54e-07	749	25	9	int:H3-3A
Interaction	EN1 interactions	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2	2.15e-07	110	25	5	int:EN1
Interaction	ZFY interactions	ZBTB9 ZFX ZFY	3.68e-07	12	25	3	int:ZFY
Interaction	MYB interactions	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2	5.55e-07	133	25	5	int:MYB
Interaction	LHX6 interactions	ZBTB9 ZNF536 ZEB1 ZNF516	7.47e-07	58	25	4	int:LHX6
Interaction	GATA2 interactions	ZBTB9 ZNF536 ZEB1 ZEB2 ZNF516	4.04e-06	199	25	5	int:GATA2
Interaction	PAX6 interactions	ZBTB9 ZNF536 ZEB1 ZNF148 ZEB2 ZNF516	4.55e-06	366	25	6	int:PAX6
Interaction	CENPA interactions	ZBTB9 ZNF536 ZNF148 TOP1 ZNF451 BRPF1	5.40e-06	377	25	6	int:CENPA
Interaction	NFIX interactions	ZBTB40 ZNF536 ZEB1 ZNF148 ZEB2	7.67e-06	227	25	5	int:NFIX
Interaction	ELK3 interactions	ZNF148 TOP1 ZEB2 ZBTB14	1.37e-05	120	25	4	int:ELK3
Interaction	ZNF330 interactions	ZBTB9 ZNF536 ZNF148 PRDM15 TOP1 BRPF1	1.41e-05	446	25	6	int:ZNF330
Interaction	H3C3 interactions	ZBTB9 ZNF148 PRDM15 TOP1 ZEB2 BRPF1	2.54e-05	495	25	6	int:H3C3
Interaction	ADAMTS16 interactions	TOP1 ZEB2	3.09e-05	7	25	2	int:ADAMTS16
Interaction	SP7 interactions	ZNF536 ZNF148 ZEB2 ZBTB14 ZNF516	3.13e-05	304	25	5	int:SP7
Interaction	KLF8 interactions	ZEB1 ZNF148 ZEB2 ZBTB14 ZNF516	4.57e-05	329	25	5	int:KLF8
Interaction	NFATC1 interactions	ZBTB40 PLOD1 PRDM15 ATF2	5.14e-05	168	25	4	int:NFATC1
Interaction	EGR2 interactions	ZBTB9 ZNF536 ZNF148 ZEB2	5.51e-05	171	25	4	int:EGR2
Interaction	FEV interactions	ZEB1 ZNF148 ZEB2 ZBTB14	1.07e-04	203	25	4	int:FEV
Interaction	ZNF407 interactions	ZBTB9 ZNF407	1.33e-04	14	25	2	int:ZNF407
Interaction	GSC interactions	ZNF536 ZEB2 ZNF516	1.67e-04	87	25	3	int:GSC
Interaction	MPHOSPH8 interactions	ZEB1 TOP1 BRPF1	2.03e-04	93	25	3	int:MPHOSPH8
Interaction	POLR1G interactions	ZBTB9 TOP1 ZEB2 BRPF1 ZNF516	2.93e-04	489	25	5	int:POLR1G
Interaction	HNF4A interactions	ZBTB9 ZNF148 ZEB2 ZNF451	3.42e-04	275	25	4	int:HNF4A
Interaction	TBXT interactions	ZNF536 ZNF148 ZEB2	3.90e-04	116	25	3	int:TBXT
Interaction	ZBTB9 interactions	ZBTB9 ZNF407 ZFY	4.00e-04	117	25	3	int:ZBTB9
Interaction	ZFX interactions	ZFX ZFY	4.01e-04	24	25	2	int:ZFX
Interaction	COIL interactions	ZBTB9 ZNF536 ZNF148 TOP1 BRPF1	5.11e-04	552	25	5	int:COIL
Interaction	USP35 interactions	ZEB1 BRPF1	5.48e-04	28	25	2	int:USP35
Interaction	CEBPA interactions	ZBTB9 ZBTB40 ZNF148 ATF2 TOP1 ZEB2 ZNF516	6.06e-04	1245	25	7	int:CEBPA
Interaction	H2BC8 interactions	ZEB1 ZNF148 PRDM15 TOP1 BRPF1	6.20e-04	576	25	5	int:H2BC8
Interaction	APEX1 interactions	ZBTB9 ZNF536 ZEB1 ZNF148 ATF2 ZBTB14 ZNF516	6.85e-04	1271	25	7	int:APEX1
Interaction	ATM interactions	ZEB1 ZNF148 ATF2 TOP1	7.04e-04	333	25	4	int:ATM
Interaction	FBXO38 interactions	ZBTB40 ZNF536 ZEB2	7.47e-04	145	25	3	int:FBXO38
Interaction	PHF21A interactions	ZBTB9 ZNF536 ZEB2 ZNF516	7.86e-04	343	25	4	int:PHF21A
Interaction	KDM1A interactions	ZBTB9 ZEB1 ZNF148 ZEB2 ZNF451 ZNF516	8.41e-04	941	25	6	int:KDM1A
Interaction	ELF2 interactions	ZBTB40 ZEB1 ZNF148	9.23e-04	156	25	3	int:ELF2
Interaction	FBLN5 interactions	ZBTB9 ZBTB40 ZNF407	9.76e-04	159	25	3	int:FBLN5
Interaction	ZBTB7B interactions	ZNF148 TOP1 ZEB2 ZNF516	1.00e-03	366	25	4	int:ZBTB7B
Interaction	UBE2I interactions	ZBTB9 ATF2 TOP1 ZEB2 ZNF451	1.10e-03	654	25	5	int:UBE2I
Cytoband	18q23	ZNF407 ZNF516	1.15e-04	29	25	2	18q23
Cytoband	Ensembl 112 genes in cytogenetic band chr18p11	APCDD1 ZBTB14	5.83e-03	210	25	2	chr18p11
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZBTB9 ZBTB40 ZNF407 ZNF536 ZEB1 ZNF148 PRDM15 ZEB2 ZNF451 ZBTB14 ZFX ZFY ZNF404 ZNF516 ZNF304	3.63e-17	718	21	15	28
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZEB1 ZEB2	1.34e-04	15	21	2	529
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB9 ZBTB40 ZBTB14	4.80e-04	134	21	3	861
GeneFamily	PHD finger proteins	BRPF1 ASH1L	4.84e-03	90	21	2	88
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	ZNF148 APCDD1 PLOD1 TOP1 ZEB2 ZNF451 ASH1L	2.57e-05	790	25	7	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_1000	ZNF148 APCDD1 ZEB2 ZFX	2.77e-05	151	25	4	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	ZNF148 APCDD1 ATF2 TOP1 ZEB2 ZNF451 ASH1L	2.81e-05	801	25	7	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500	ZNF148 APCDD1 ZNF451 ZBTB14	1.86e-04	247	25	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000	TOP1 ZEB2 ZNF451 ASH1L	2.24e-04	259	25	4	gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000	ZNF148 APCDD1 ZEB2 ZNF451 ZBTB14	2.37e-04	492	25	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	ZNF148 TOP1 ZEB2 ZNF451 ZFX ASH1L	2.76e-04	804	25	6	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	ATF2 TOP1 ZNF451 ASH1L	2.81e-04	275	25	4	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000	TOP1 ZEB2 ZNF451 ASH1L	2.89e-04	277	25	4	gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000	ZNF148 TOP1 ZEB2 ZNF451 ZFX ASH1L	2.97e-04	815	25	6	gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_1000	TOP1 ZEB2 ZNF451 ASH1L	3.18e-04	284	25	4	gudmap_developingGonad_e16.5_epididymis_1000_k2
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3	ZBTB14 BRPF1 ZFX SKIDA1	4.64e-04	314	25	4	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K3
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000	TOP1 ZEB2 ZNF451 ASH1L	5.16e-04	323	25	4	gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500	TOP1 ZEB2 ASH1L	7.09e-04	150	25	3	gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500	TOP1 ZEB2 ASH1L	7.37e-04	152	25	3	gudmap_developingGonad_e18.5_epididymis_500_k4
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_500	TOP1 ZEB2 ASH1L	8.70e-04	161	25	3	gudmap_developingGonad_e12.5_ovary_k3_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500	TOP1 ZEB2 ASH1L	8.86e-04	162	25	3	gudmap_developingGonad_e16.5_epididymis_500_k2
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_500	TOP1 ZEB2 ASH1L	1.05e-03	172	25	3	gudmap_developingGonad_e11.5_ovary + mesonephros_k4_500
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500	ZNF148 TOP1 ZEB2 ASH1L	1.18e-03	403	25	4	gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500	ZNF148 TOP1 ZEB2 ASH1L	1.19e-03	404	25	4	gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	ZNF148 TOP1 ZEB2 ASH1L	1.21e-03	406	25	4	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500	ZNF148 TOP1 ZEB2 ASH1L	1.25e-03	409	25	4	gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	ZNF148 TOP1 ZEB2 ASH1L	1.29e-03	413	25	4	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500	ZNF148 TOP1 ZEB2 ASH1L	1.34e-03	417	25	4	gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500	ZNF148 APCDD1 ZNF451 ZBTB14	1.48e-03	429	25	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
ToppCell	Control-PLT_4\|Control / Disease Group and Platelet Clusters	ZNF148 TOP1 ZNF451 PRR13	4.28e-06	198	25	4	387fd3037fd52e4d4c42de0588767e58af228b59
ToppCell	Control-PLT_4\|World / Disease Group and Platelet Clusters	TOP1 PRR13 ZNF304	8.56e-05	154	25	3	a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZEB2 ZBTB14 ZNF516	1.29e-04	177	25	3	68f1139fc378f351e3b9e9f392aacb150025bf03
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZEB1 APCDD1 ZEB2	1.47e-04	185	25	3	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	BAL-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	ZBTB9 ZFX SKIDA1	1.47e-04	185	25	3	e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZEB1 APCDD1 ZEB2	1.47e-04	185	25	3	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZNF536 ZEB1 ZEB2	1.50e-04	186	25	3	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	ZBTB40 ZEB2 ASH1L	1.50e-04	186	25	3	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ZNF407 ZEB2 ASH1L	1.54e-04	188	25	3	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	COVID-19_Mild-PLT_4\|World / Disease Group and Platelet Clusters	TOP1 ZEB2 ZNF451	1.67e-04	193	25	3	98a52523aa1efd5d14a2878ed106828a80a33aa2
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TLCD3B ZNF536 ZEB2	1.74e-04	196	25	3	e874aa82a20bb59582c8cd7f8d30b2ed02903a85
ToppCell	3'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 APCDD1 ZEB2	1.80e-04	198	25	3	2488ea95003f218afb25ecc873805b825e6cc409
ToppCell	3'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 APCDD1 ZEB2	1.80e-04	198	25	3	98ab27335d126fa7817a46953948e524d91248f8
ToppCell	3'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 APCDD1 ZEB2	1.80e-04	198	25	3	991db02a76f7506848827601e927cf997cb520d3
ToppCell	COVID-19_Mild-PLT_4\|COVID-19_Mild / Disease Group and Platelet Clusters	TOP1 ZEB2 ZNF451	1.80e-04	198	25	3	3d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF407 ZNF451 ASH1L	1.82e-04	199	25	3	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZNF536 APCDD1 ZEB2	1.82e-04	199	25	3	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF536 KIF6 ZEB2	1.85e-04	200	25	3	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF536 KIF6 ZEB2	1.85e-04	200	25	3	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF536 KIF6 ZEB2	1.85e-04	200	25	3	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF536 KIF6 ZEB2	1.85e-04	200	25	3	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF536 KIF6 ZEB2	1.85e-04	200	25	3	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF536 KIF6 ZEB2	1.85e-04	200	25	3	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZEB1 APCDD1 ZEB2	1.85e-04	200	25	3	58b38f9a484ee94191091a0659ed62ebed2d4a14
Computational	Genes in the cancer module 123.	ATF2 ZEB2 ZFX ZNF516	5.12e-04	247	17	4	MODULE_123
Computational	Neighborhood of TNFRSF6	ZBTB40 ATF2 ZBTB14	2.13e-03	167	17	3	MORF_TNFRSF6
Computational	Neighborhood of PPP2R5B	ZBTB40 ATF2 ZBTB14	2.36e-03	173	17	3	MORF_PPP2R5B
Computational	Neighborhood of DMPK	ZBTB40 ATF2 ZBTB14	2.44e-03	175	17	3	MORF_DMPK
Computational	Neighborhood of PRKCA	ZBTB40 ATF2 ZBTB14	2.68e-03	181	17	3	MORF_PRKCA
Computational	Neighborhood of MAP2K7	ZBTB40 ATF2 ZBTB14	2.68e-03	181	17	3	MORF_MAP2K7
Computational	Neighborhood of CTSB	ZBTB40 ATF2 ZBTB14	2.94e-03	187	17	3	MORF_CTSB
Computational	Neighborhood of PTPRD	ZNF536 ZEB2	3.69e-03	58	17	2	GCM_PTPRD
Computational	Neighborhood of IFNA1	ZBTB40 ATF2 ZBTB14	3.82e-03	205	17	3	MORF_IFNA1
Drug	vinylene	ZNF536 ZNF148 PRDM15 ZBTB14 ZFX ZFY ZNF304	6.25e-09	245	25	7	CID000006326
Disease	Disease Exacerbation	ZEB1 ATF2 TOP1 ZEB2	9.18e-06	165	24	4	C0235874
Disease	Malignant neoplasm of breast	KIF6 ZEB1 PLOD1 ATF2 TOP1 ZEB2 ZNF404	1.67e-05	1074	24	7	C0006142
Disease	rheumatic heart disease (biomarker_via_orthology)	ZEB1 ZEB2	4.16e-05	12	24	2	DOID:0050827 (biomarker_via_orthology)
Disease	Familial Nonmedullary Thyroid Cancer	ZEB1 ZEB2	1.13e-03	61	24	2	C3501844
Disease	Nonmedullary Thyroid Carcinoma	ZEB1 ZEB2	1.13e-03	61	24	2	C3501843
Disease	pyruvate measurement	ZNF536 PRDM15 ASH1L	1.30e-03	268	24	3	EFO_0010117
Disease	Benign Neoplasm	ATF2 TOP1	1.40e-03	68	24	2	C0086692
Disease	Neoplasms	ATF2 TOP1	1.40e-03	68	24	2	C0027651
Disease	Papillary thyroid carcinoma	ZEB1 ZEB2	2.22e-03	86	24	2	C0238463
Disease	C-reactive protein measurement	ZBTB9 ZBTB40 ZNF536 ZEB1 TOP1	2.51e-03	1206	24	5	EFO_0004458
Disease	pathological myopia	ZNF536 ZEB2	3.67e-03	111	24	2	EFO_0004207
Disease	cortical surface area measurement	ZNF536 KIF6 APCDD1 PRR13 SKIDA1	4.02e-03	1345	24	5	EFO_0010736
Disease	Malignant Neoplasms	ATF2 TOP1	4.84e-03	128	24	2	C0006826
Disease	insomnia measurement	ZBTB9 ZNF536 PRDM15	5.38e-03	443	24	3	EFO_0007876
Disease	corneal resistance factor	ZNF407 TOP1 ZNF516	5.66e-03	451	24	3	EFO_0010067
Disease	Neoplastic Cell Transformation	ZEB1 ZEB2	5.68e-03	139	24	2	C0007621
Disease	cataract	TLCD3B TOP1	5.84e-03	141	24	2	MONDO_0005129
Disease	Malignant neoplasm of liver	TOP1 ASH1L	5.92e-03	142	24	2	C0345904
Disease	Liver neoplasms	TOP1 ASH1L	5.92e-03	142	24	2	C0023903

Protein segments in the cluster

Peptide	Gene	Start	Entry
ERYKHKEKHRCHMSC	ASH1L	1526	Q9NR48
HLAVHKHKHEMTLKF	ATF2	41	P15336
ADMRKVHHCFHHLKK	KIF6	416	Q6ZMV9
AHKKMHKHQKHHKYH	PRR13	116	Q9NZ81
KHMRLFIHNHEQHHK	PLOD1	316	Q02809
AFKESQCHHMLKHLH	APCDD1	46	Q8J025
MKTKHALRHHMKLHK	PRDM15	1121	P57071
HKRMDHLKVKKHHCD	SKIDA1	46	Q1XH10
HKNKEKRKDSNHHHH	BRPF1	151	P55201
HMKKHRGSFDHGCHI	ZNF516	266	Q92618
FACHMCDKAFKHKSH	ZBTB14	361	O43829
VKQHCMSLASHKFHR	ZNF451	621	Q9Y4E5
ICKKAFKHKHHLIEH	ZEB1	936	P37275
FKHKHHLIEHMRLHS	ZEB1	941	P37275
RHMCLHQKIHHGVKP	ZNF404	256	Q494X3
KGHMRKHKDSFEHCC	ZNF536	361	O15090
CNKRFKLKHHLTEHM	ZBTB9	416	Q96C00
VAAHKGKKMHQCRHC	ZFX	681	P17010
AMFLCHWHKHQVKGH	TLCD3B	91	Q71RH2
KAFIHLHHLKMHQKF	ZNF304	286	Q9HCX3
LHHLKMHQKFHTGKR	ZNF304	291	Q9HCX3
LKHKRMCHENHDKKL	ZNF148	271	Q9UQR1
VHIAMKHPTKEKHFH	ZNF407	1431	Q9C0G0
ICKKAFKHKHHLIEH	ZEB2	1031	O60315
SHKHKDKHKDREHRH	TOP1	21	P11387
HKKHIKAEHADMKFH	ZBTB40	1061	Q9NUA8
HVAVHKGKKMHQCRH	ZFY	676	P08048