Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 IFT140 VPS4A ASH1L PEX1 BIRC2 RICTOR ZZEF1 FMNL2 TF EIF4ENIF1 GLI3 WDR20 RTL9 CEP295 TAF2 WDFY3 SAP130 NOS1AP

1.29e-0811161221931753913
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZSWIM8 DMXL2 CLSTN3 KALRN RBL2 LRSAM1 UBR4 ASH1L TRIOBP BIRC2 PSMD1 OAZ1 MSH3 FMNL2 TF GTF3C4 GRHPR ARID5B WDFY3

1.18e-0712851221935914814
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

POU6F2 LRRC4C FMNL2 UMODL1 GLI3 ARID5B PLCH1 NSMAF

5.50e-07199122823382691
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SGSM1 ACACA TTC21A UBR4 IGDCC3 ZZEF1 FMNL2 SNAI3 CHRNB4 MDN1 GRHPR ARID5B CEP295

2.04e-067361221329676528
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ANKFY1 UBR4 MUC16 ZNF568 LRR1 MDN1 ZNF665 SYNE2 ARID5B CEP295 TAF2 WDFY3

2.72e-066381221231182584
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

FOXK2 KCMF1 UBR4 MDN1 GLI3 ARID5B TAF2 SAP130

7.33e-06282122823667531
Pubmed

Human transcription factor protein interaction networks.

FOXK2 KCMF1 UBR4 GPS2 PSMD1 EIF4ENIF1 PRRC2C GLI3 WDR20 SYNE2 ARID5B NT5C2 ZBTB40 TAF2 CLP1 SAP130 CPEB1

1.07e-0514291221735140242
Pubmed

Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons.

SYTL2 CAMK1G

1.22e-052122220729199
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZSWIM8 DNAJC13 UBR4 SYNE2 WDFY3

1.44e-0587122512465718
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DMXL2 ANKFY1 HECW1 TRIOBP SYNE2 ZBTB40 WDFY3

1.54e-05225122712168954
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

DNAJC13 ANKFY1 ACACA UBR4 PSMD1 GTF3C4 EIF4ENIF1 ARID5B CLP1

1.77e-05418122934709266
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

POU6F2 DNAJC13 FOXK2 SGSM1 ACACA TTC21A ASH1L ZDHHC14 TRIOBP PSMD1 ITFG1 HIVEP3 ARID5B NT5C2 SAP130 SH3RF3 NSMAF

1.82e-0514891221728611215
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ZSWIM8 ACACA KALRN ABCA13 SYTL2 MUC16 FMNL2 PDE8B NT5C2 ZBTB40

2.63e-055521221010737800
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 DNAJC13 ANKFY1 HECW1 KALRN UBR4 TRIOBP MDN1 PRRC2C SYNE2 NT5C2 WDFY3 NUP153

3.53e-059631221328671696
Pubmed

Stress response silencing by an E3 ligase mutated in neurodegeneration.

KCMF1 UBR4

3.65e-053122238297121
Pubmed

Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.

BRIP1 MSH3 NUP153

3.92e-0519122314578343
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DMXL2 HECW1 SYTL2 RICTOR FMNL2 HIVEP3 ZNF665 PLCH1 FAM135A

6.36e-05493122915368895
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MYH8 AP5S1 ACACA RBL2 KCMF1 UBR4 GPS2 RICTOR OAZ1 GLI3 WDR20 ARID5B NT5C2 ZBTB40 CPEB1

6.58e-0513271221532694731
Pubmed

Bone morphogenic factor gene dosage abnormalities in prostatic intraepithelial neoplasia and prostate cancer.

BMP7 PBOV1

7.29e-054122217656261
Pubmed

Expression of man, a formin homology domain-containing gene in the mouse limb.

FMNL2 BMP7

7.29e-054122216094489
Pubmed

The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis.

HIVEP3 PIK3CD

7.29e-054122221390242
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

ASH1L EIF4ENIF1 PRRC2C SYNE2 NUP153

7.59e-05123122526912792
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DNAJC13 ANKFY1 ACACA VPS4A LRSAM1 UBR4 PSMD1 RICTOR MSH3 GTF3C4 PTPN12 MDN1 GRHPR TAF2 WDFY3

8.17e-0513531221529467282
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

KCMF1 UBR4 GPS2 MUC16 POU1F1 GTF3C4 PTPN12 SAP130

8.19e-05396122826687479
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FOXK2 ZNF569 ASH1L PEX1 PSMD1 RICTOR ZNF568 PIK3CD ARID5B ZBTB40 CEP295 FAM135A NUP153

1.16e-0410841221311544199
Pubmed

Combining Homologous Recombination and Phosphopeptide-binding Data to Predict the Impact of BRCA1 BRCT Variants on Cancer Risk.

BRIP1 ACACA

1.21e-045122230257991
Pubmed

N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.

KCMF1 UBR4

1.21e-045122237891180
Pubmed

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes.

TF WDFY3

1.21e-045122215292400
Pubmed

Isolation, mapping, and regulated expression of the gene encoding mouse C-type natriuretic peptide.

CHRNG UGT1A1

1.21e-04512228897953
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

ZSWIM8 KCMF1 UBR4 PEX1 BIRC2 PSMD1 FMNL2

1.24e-04313122738270169
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ACACA UBR4 ASH1L PSMD1 RICTOR ZZEF1 GTF3C4 HIVEP3 MDN1 GRHPR NT5C2

1.33e-048071221130575818
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ANKFY1 ZNF48 ZNF569 KCMF1 ASH1L ZDHHC14 HIVEP3 ZNF665 GLI3 ARID5B ZNF654

1.35e-048081221120412781
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

IFT140 PEX1 EIF4ENIF1 GLI3 PLCH1 NUP153

1.75e-04232122625515538
Pubmed

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.

HECW1 KCMF1 UBR4 PSMD1

1.77e-0479122427325702
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KALRN UBR4 SPATA31D4 SPATA31D3 GLI3 CEP295

1.79e-04233122637704626
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC6

1.81e-046122219110483
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXK2 RBL2 UBR4 GPS2 MSH3 GTF3C4 MDN1 NFATC2IP PRRC2C ZBTB40 SAP130

2.24e-048571221125609649
Pubmed

Functional proteomics mapping of a human signaling pathway.

UBR4 SYTL2 ASH1L PSMD1 ZZEF1 FMNL2 TINAGL1 PTPN12 SAP130

2.48e-04591122915231748
Pubmed

BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.

BMP7 GLI3

2.53e-047122219505455
Pubmed

Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): comparison with the human CNP gene (NPPC).

CHRNG UGT1A1

2.53e-04712227698765
Pubmed

The N-terminal cysteine is a dual sensor of oxygen and oxidative stress.

KCMF1 UBR4

2.53e-047122234893540
Pubmed

Patterning events and specification signals in the developing hippocampus.

BMP7 GLI3

3.37e-048122210498273
Pubmed

Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation.

BMP7 GLI3

3.37e-048122212221011
Pubmed

Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.

ANKFY1 ZZEF1

3.37e-048122224039173
Pubmed

Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.

POU1F1 PDE8B

3.37e-048122218514160
Pubmed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

IFT140 DMXL2 SAP130

3.78e-0440122329078390
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

GPS2 GTF3C4 NFATC2IP ARID5B CLP1 SAP130

3.79e-04268122633640491
Pubmed

Mapping genes encoding drug-metabolizing enzymes in recombinant inbred mice.

CHRNG UGT1A1

4.32e-04912221685137
Pubmed

Confirmation of quantitative trait loci for cocaine-induced activation in the AcB/BcA series of recombinant congenic strains.

HTR5A CHRNG

4.32e-049122212777963
Pubmed

A large-scale candidate gene association study of age at menarche and age at natural menopause.

HTR5A POU1F1 CHRNB4 CHRNG UGT1A1 BMP7

4.35e-04275122620734064
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOXK2 ZNF48 ACACA KALRN UBR4 ZZEF1 TINAGL1 HIVEP3 MDN1 EIF4ENIF1 PIK3CD WDFY3

5.24e-0411051221235748872
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DMXL2 MSH3 WDR20 WDFY3 TRAPPC14 FAM135A

5.25e-04285122634369648
Pubmed

The functional interactome landscape of the human histone deacetylase family.

GPS2 MDN1 SYNE2 ARID5B SAP130 NUP153

5.64e-04289122623752268
Pubmed

Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling.

BMP7 GLI3

6.57e-0411122214723846
Pubmed

Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.

BMP7 GLI3

6.57e-0411122219389374
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ACACA TRIOBP RICTOR WDR20 PLCH1 FAM135A NOS1AP

7.36e-04421122736976175
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

IFT140 DNAJC13 FOXK2 VPS4A TTC21A FMNL2 TF GTF3C4 EIF4ENIF1 GLI3 WDR20 RTL9 SH3RF3

7.67e-0413211221327173435
Pubmed

De novo genic mutations among a Chinese autism spectrum disorder cohort.

HIVEP3 WDFY3

7.87e-0412122227824329
Pubmed

Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development.

BMP7 GLI3

7.87e-041212229152009
Pubmed

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells.

HIVEP3 NFATC2IP

7.87e-0412122215790681
Pubmed

Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner.

BMP7 GLI3

7.87e-0412122223994639
Pubmed

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.

CHRNB4 CHRNG

7.87e-0412122220584212
Pubmed

Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps.

BMP7 GLI3

9.28e-0413122216916379
Pubmed

Cauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndrome.

IFT140 GLI3

9.28e-0413122224009529
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

ACACA KCMF1 UBR4 BIRC2 ZZEF1

9.34e-04212122533853758
Pubmed

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.

ANKFY1 PEX1 SYNE2

9.67e-0455122318570454
Pubmed

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PSMD1 CHRNG UGT1A1 EVA1A WDFY3 SAP130 PSD4

9.77e-04442122715815621
Pubmed

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

UBR4 ZBTB40 NOS1AP

1.02e-035612239455484
Pubmed

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.

CLSTN3 SYTL2 ZDHHC14

1.02e-0356122330104731
Pubmed

Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.

HECW1 GLI3

1.08e-0314122211472062
Pubmed

Lrp4 modulates extracellular integration of cell signaling pathways in development.

BMP7 GLI3

1.08e-0314122219116665
Pubmed

BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period.

BMP7 GLI3

1.08e-0314122237300483
Pubmed

The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice.

BMP7 GLI3

1.08e-031412229584130
Pubmed

Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.

CHRNB4 CHRNG

1.08e-0314122219059502
Pubmed

A whole genome association study of mother-to-child transmission of HIV in Malawi.

GRID2 GTF3C4

1.08e-0314122220487506
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DNAJC13 TRIOBP PSMD1 RICTOR DUSP22 PTP4A3 PTPN12 WDR20 SYNE2 NUP153 NOS1AP

1.19e-0310491221127880917
Pubmed

Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.

CHRNB4 CHRNG

1.24e-031512228838678
Pubmed

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.

TTC21A GLI3

1.24e-0315122218327258
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

DNAJC13 ANKFY1 VPS4A TRIOBP OAS2

1.29e-03228122530471916
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

ANKFY1 LRSAM1 KCMF1 UBR4 BIRC2 LRR1 TAF2 OPLAH

1.35e-03604122838803224
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

DNAJC13 ACACA VPS4A PEX1 RICTOR GTF3C4 MDN1 PRRC2C

1.38e-03606122836538041
Pubmed

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.

ASH1L WDFY3

1.42e-0316122216096065
Pubmed

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.

CHRNB4 CHRNG

1.42e-0316122219259974
Pubmed

Esophageal Atresia / Tracheoesophageal Fistula Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

BRIP1 GLI3

1.42e-0316122220301753
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

ZNF569 TTC21A RICTOR ZNF568 USP38 ZNF256 NT5C2 CFAP74 ZNF654 PSD4

1.47e-039151221032393512
Pubmed

Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis.

IFT140 GLI3

1.60e-0317122223955340
Pubmed

Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J).

BMP7 GLI3

1.60e-0317122210625551
Pubmed

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

UBR4 USP38 PRRC2C

1.64e-0366122324811749
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DNAJC13 BRIP1 ACACA PSMD1 RICTOR GTF3C4 MDN1 ZBTB40 NUP153

1.67e-03774122915302935
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

DNAJC13 ANKFY1 ABCA13 UBR4 PRRC2C NUP153

1.77e-03361122626167880
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

ANKFY1 ACACA TTC21A CYBC1 DDR2 PSMD1 OAS2 TINAGL1 PIK3CD WDR20 IFIT1B NT5C2 SAP130

1.78e-0314511221330550785
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC6

1.80e-0318122218834073
Pubmed

Pitx1 and Pitx2 are required for development of hindlimb buds.

BMP7 GLI3

1.80e-0318122212441290
Pubmed

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1.

TF SYNE2

1.80e-0318122233361760
Pubmed

Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition.

BMP7 GLI3

1.80e-031812229716414
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

ZSWIM8 DMXL2 RICTOR USP38

1.83e-03147122429576527
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

DMXL2 MYH8 ANKFY1 KALRN PSMD1 SYNE2 ZBTB40

1.91e-03497122723414517
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

GTF3C4 MDN1 ARID5B SAP130

1.97e-03150122428242625
Pubmed

Autoregulation of the 26S proteasome by in situ ubiquitination.

UBR4 PSMD1

2.01e-0319122224743594
Pubmed

The ciliary protein Ftm is required for ventricular wall and septal development.

DDR2 GLI3

2.01e-0319122223469020
CoexpressionGSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN

USP18 DNAJC13 ANKFY1 OAS2 SYNE2 IFIT1B ZNF654 NUP153

4.30e-062001218M9020
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DMXL2 DNAJC13 FOXK2 DDR2 MSH3 ZZEF1 PTPN12 MDN1 PRRC2C SYNE2 ARID5B NT5C2 WDFY3 NUP153 NSMAF

9.80e-0685612115M4500
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000

DNAJC13 ANKFY1 ASH1L PRRC2C SYNE2 ARID5B CEP295 WDFY3

7.25e-052491178gudmap_developingGonad_P2_epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000

DNAJC13 ANKFY1 ASH1L PRRC2C SYNE2 ARID5B CEP295 WDFY3 NUP153

7.64e-053231179gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

DNAJC13 ANKFY1 ASH1L PRRC2C SYNE2 ARID5B CEP295 WDFY3

9.54e-052591178gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_500

ASH1L PRRC2C SYNE2 ARID5B CEP295 WDFY3

1.08e-041361176gudmap_developingGonad_P2_epididymis_500_k2
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#1_top-relative-expression-ranked_1000

SYTL2 TINAGL1 PTP4A3 SYNE2 WDFY3

1.41e-04901175gudmap_kidney_adult_JuxtaGlom_Ren1_k1_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000

DNAJC13 ANKFY1 ASH1L PRRC2C SYNE2 ARID5B CEP295 WDFY3

1.52e-042771178gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000

DNAJC13 ASH1L PRRC2C SYNE2 CEP295 WDFY3 NUP153

1.66e-042101177gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000

DNAJC13 ANKFY1 ASH1L PRRC2C SYNE2 ARID5B CEP295 WDFY3

1.67e-042811178gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

DNAJC13 ASH1L PRRC2C SYNE2 CEP295 WDFY3

1.85e-041501176gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000

DNAJC13 ASH1L PRRC2C SYNE2 CEP295 WDFY3

1.91e-041511176gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500

ANKFY1 ASH1L PRRC2C SYNE2 ARID5B WDFY3

1.98e-041521176gudmap_developingGonad_e18.5_epididymis_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_1000

DDR2 MSH3 BMP7 LRR1 EVA1A TAF2 PLCH1 FAM135A

2.22e-042931178gudmap_developingKidney_e15.5_Podocyte cells_1000_k4
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500

DNAJC13 ANKFY1 ASH1L PRRC2C CEP295 WDFY3

2.80e-041621176gudmap_developingGonad_e16.5_epididymis_500_k2
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

DNAJC13 ANKFY1 ASH1L PRRC2C SYNE2 CEP295 WDFY3

2.89e-042301177gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500

ANKRD42 DMXL2 DNAJC13 ASH1L GRID2 PDE8B SYNE2 CEP295 CPEB1

2.96e-043871179gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500

DMXL2 MYH8 DNAJC13 ASH1L PDE8B SYNE2 CEP295 WDFY3 CPEB1

2.96e-043871179gudmap_developingGonad_e16.5_ovary_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500

DNAJC13 ANKFY1 ASH1L SYNE2 CEP295

3.17e-041071175gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

DMXL2 MYH8 DNAJC13 ANKFY1 ASH1L RICTOR LRR1 PTPN12 PDE8B SYNE2 CEP295 NUP153 CPEB1

3.51e-0477611713gudmap_developingGonad_e14.5_ ovary_1000
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

ABCA13 MUC16 SYNE2 PLCH1 ANKFN1 CPEB1

4.58e-06156122610d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 TTC21A SYTL2 MUC16 CFAP74 ANKFN1

7.25e-06169122614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellBAL-Control-Lymphocyte-B-B_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLSTN3 ZNF48 HIVEP3 GPR68 SYNE2 ARID5B

1.41e-051901226da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCellBAL-Control-Lymphocyte-B-B_cell-B_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLSTN3 ZNF48 HIVEP3 GPR68 SYNE2 ARID5B

1.41e-05190122642312f7d79fe889397d32910b625793e2535cc26
ToppCellBAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLSTN3 ZNF48 HIVEP3 GPR68 SYNE2 ARID5B

1.41e-051901226682418a7a2096743112eae3790d40e7e600612c0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN DDR2 NEGR1 GLI3 ANKFN1 SH3RF3

1.45e-051911226a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN DDR2 NEGR1 GLI3 ANKFN1 SH3RF3

1.45e-0519112268f6d592edc32fdb901af30501d4360512334e8c2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH8 ABCA13 LRRC4C TINAGL1 BMP7 SYNE2

1.54e-051931226ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRC4C TINAGL1 BMP7 SYNE2 WDFY3

1.59e-0519412268ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

USP18 SYTL2 ASH1L OAS2 SYNE2 ARID5B

1.83e-051991226952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

CLSTN3 SYTL2 OAS2 PTPN12 SYNE2 PSD4

1.89e-0520012262281debd86e5d92e8fe0397aec9ef670800f7471
DrugHymecromone [90-33-5]; Down 200; 22.8uM; PC3; HT_HG-U133A

IFT140 BRIP1 ANKFY1 SYTL2 PEX1 PTPN12 PDE8B WDFY3 PLCH1

9.35e-0719312194623_DN
DrugDemecarium bromide [56-94-0]; Down 200; 5.6uM; HL60; HG-U133A

ZSWIM8 AP5S1 BRIP1 ANKFY1 ACACA MSH3 BMP7 GRHPR CFAP74

1.06e-0619612191781_DN
DrugMethylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; HL60; HT_HG-U133A

IFT140 KALRN DDR2 POU1F1 OAS2 ZZEF1 PDE8B TNP2

1.06e-0519712183040_UP
DrugHalofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; HL60; HT_HG-U133A

ZSWIM8 AP5S1 PEX1 CHRNG BMP7 PIK3CD GLI3 PSD4

1.19e-0520012183130_UP
Diseaseserum IgG glycosylation measurement

POU6F2 CLSTN3 LRRC4C FMNL2 UMODL1 GLI3 ARID5B PLCH1 ANKFN1 NSMAF

3.97e-0552311510EFO_0005193
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

WDFY3 NSMAF

8.99e-0541152DOID:2935 (implicated_via_orthology)
Diseasecognitive function measurement

DMXL2 POU6F2 ANKFY1 SGSM1 KALRN RBL2 DHRS11 TRIOBP GRID2 PKD1L3 NFATC2IP NEGR1 PRRC2C GLI3 TAF2 SH3RF3

1.42e-04143411516EFO_0008354
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

DMXL2 RBL2 DHRS11 TRIOBP GRID2 PKD1L3 NEGR1 CPEB1

1.72e-043981158EFO_0003756, EFO_0003888, EFO_0004337
Diseaseneonatal abstinence syndrome

KALRN ZDHHC14 FMNL2 NOS1AP

2.38e-04771154EFO_0005799
Diseaseendometrial cancer (is_implicated_in)

MSH3 UGT1A1 PIK3CD

3.75e-04361153DOID:1380 (is_implicated_in)
DiseaseColorectal Carcinoma

CLSTN3 ACACA HTR5A KALRN ZNF569 ABCA13 ADAM29 GRID2 HIVEP3 GLI3

4.32e-0470211510C0009402
Diseaseeye color

POU6F2 MUC16 HIVEP3 BMP7

4.32e-04901154EFO_0003949
Diseasecognitive function measurement, self reported educational attainment

DMXL2 RBL2 DHRS11 TRIOBP PKD1L3 NEGR1 CPEB1

4.96e-043551157EFO_0004784, EFO_0008354
DiseaseDNA methylation

DNHD1 POU6F2 ABCA13 LRRC4C BMP7 MDN1 EVA1A GLI3 NOS1AP

1.09e-036561159GO_0006306
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

DMXL2 TRIOBP

1.14e-03131152C1846647
DiseaseAbnormality of refraction

POU6F2 DNAJC13 BRIP1 LRRC4C ZZEF1 CHRNG HIVEP3 BMP7 GLI3

1.30e-036731159HP_0000539
Diseasecolorectal cancer (is_implicated_in)

BRIP1 DDR2 PTPN12 PIK3CD

1.31e-031211154DOID:9256 (is_implicated_in)
Diseasesmoking behavior, body mass index

DMXL2 CHRNB4 NEGR1 NT5C2

1.39e-031231154EFO_0004318, EFO_0004340
Diseaselung small cell carcinoma (is_marker_for)

RICTOR CHRNB4

1.74e-03161152DOID:5409 (is_marker_for)
Disease5-oxoproline measurement

LRRC4C OPLAH

1.74e-03161152EFO_0010988
DiseaseRolandic epilepsy

KALRN CHRNB4

1.74e-03161152Orphanet_1945
Diseaseresponse to haloperidol

ZNF665 ARID5B

1.74e-03161152GO_1905119
Diseasesmoking cessation

ZSWIM8 GRID2 LRRC4C CHRNB4 EIF4ENIF1 NOS1AP

1.76e-033251156EFO_0004319
Diseasetotal blood protein measurement

ZSWIM8 CLSTN3 DNAJC13 TF DUSP22 NFATC2IP ARID5B

1.93e-034491157EFO_0004536
Diseasecortical surface area measurement

DNAJC13 FAM178B TRIOBP FMNL2 TINAGL1 BMP7 USP38 PIK3CD PRRC2C GLI3 NT5C2 ANKFN1 SH3RF3

2.26e-03134511513EFO_0010736
Diseaseglaucoma

POU6F2 KALRN TRIOBP FMNL2

3.15e-031541154MONDO_0005041
Diseasecervical squamous cell carcinoma (is_marker_for)

BRIP1 BIRC2

3.31e-03221152DOID:3744 (is_marker_for)
DiseaseDisproportionate short stature

IFT140 DDR2 GLI3

3.42e-03771153C0878659
Diseasearginine measurement

POU6F2 TINAGL1

3.61e-03231152EFO_0020990

Protein segments in the cluster

PeptideGeneStartEntry
LVTSALQPMASTVHH

UMODL1

201

Q5DID0
VLNVHHRSPSTHTMA

CHRNB4

316

P30926
NITPRMQHDTSHLFT

ADAM29

276

Q9UKF5
LHLHSRQGSMIQTLA

ASH1L

1136

Q9NR48
LHSMNRVAHPSHVLS

CLSTN3

801

Q9BQT9
LFRAAHVLMPHESTV

NT5C2

476

P49902
VETHSLQMLHTILST

AACS

396

Q86V21
VLNVSLRSPHTHSMA

CHRNG

326

P07510
SDSSSLRPMHPQALH

GPS2

266

Q13227
RDVFNSLMPVVHHTS

ABCA13

1636

Q86UQ4
HMTQHISPTQRAEVI

ACACA

2321

Q13085
MVHAFLIHTLRAPNT

AP5S1

1

Q9NUS5
SRSHSTHMNILAPTV

DMXL2

596

Q8TDJ6
ARVLSSHLMHSSLPG

DMXL2

1511

Q8TDJ6
RMSTTLELHSPVLQH

DNHD1

1061

Q96M86
MHVRSLRAAAPHSFV

BMP7

1

P18075
ATHGHSFTLQIMLRS

ANKRD42

106

Q8N9B4
SHSPEHVEMALLSNI

EVA1A

6

Q9H8M9
LSMITLIGLSSHLHT

OR8G2P

56

Q6IF36
TATHSLSRLHTMLTG

RBL2

421

Q08999
SLADSVHLQTPLHMA

ANKFY1

536

Q9P2R3
SMHKLHSSVSIHSQP

MUC16

6021

Q8WXI7
LVITHSTMTQRLPHS

MUC16

7351

Q8WXI7
STHTVIIPTHTQMAT

MUC6

1851

Q6W4X9
IIPTHTQMATSASIH

MUC6

1856

Q6W4X9
LDHNFMTASIPTHRL

MSH3

276

P20585
MTASIPTHRLFVHVR

MSH3

281

P20585
MRLVASELHTSLHSS

MDN1

3411

Q9NU22
SSAPVSLHMHQQILS

GLI3

351

P10071
THSTLLANGSLMIRH

IGDCC3

86

Q8IVU1
QTQHTPRTMQVHLTV

NEGR1

121

Q7Z3B1
TTTMNLHSVAHTVVL

LRR1

371

Q96L50
AHHRLSLDLLSQMSP

LRSAM1

591

Q6UWE0
ARFVTVPLHHRMASA

DDR2

331

Q16832
LHMLATHASASASLP

FOXK2

601

Q01167
IRIHTLLHSMPSAQG

HECW1

561

Q76N89
PHRVEASLLHATGMT

FAM135A

41

Q9P2D6
AMHIPHLFIQRSTAG

GRID2

111

O43424
LMTNLRSTHPHFVRC

MYH8

661

P13535
NVHQSHSHLAMPITI

PDE8B

526

O95263
HRNNVSMPSVASHTR

KALRN

1081

O60229
SPSLSHSDIVMATLH

LMLN2

291

A0A1B0GTW7
LLVTSDHNPSMTHLR

LMLN2

721

A0A1B0GTW7
SIHSSVHEPLLIRMN

LRRC4C

616

Q9HCJ2
HPIVNEMFSSRSHRI

OAS2

696

P29728
ATIHASRTMPLLSLH

OAZ1

26

P54368
LQQQRMHPSLSHSEA

RICTOR

1336

Q6R327
SLHISSSLVPMHQGS

CAMK1G

396

Q96NX5
VPMTILSSRDHTCVH

BRIP1

271

Q9BX63
LPHIGSATHRTRNTM

GRHPR

291

Q9UBQ7
MALETTPTSAFLHHQ

IFIT1B

276

Q5T764
HPLTQSAVMGHRSDV

CYBC1

136

Q9BQA9
FHRVPHNLVASMAVS

HTR5A

71

P47898
VMSHPHAVNEIALSL

FMNL2

241

Q96PY5
PRHLHTAMFTISSDQ

DNAJC13

611

O75165
VTHILSVHDSARPML

DUSP22

31

Q9NRW4
THRDSLALFPHMATT

HEPHL1

671

Q6MZM0
DLTTATLMHQIPCHS

NSMAF

791

Q92636
ATTTRHTTDHPMQCI

KCMF1

41

Q9P0J7
QSSTHSVLSMLHNPL

CPEB1

121

Q9BZB8
LGTETPLSTHHQMQL

NOS1AP

281

O75052
TSHSIISQMHDRPLL

CEP295

821

Q9C0D2
SMSGHRVLPLSVTHF

DHRS11

151

Q6UWP2
HTMPLTHTADITVLR

IFT140

96

Q96RY7
RLAISQSHLMTALGH

PEX1

1226

O43933
QSHLMTALGHTRPSI

PEX1

1231

O43933
MSSLHVSSPHQRASA

BVES

316

Q8NE79
VYVINSHLSMSSPTH

CFAP74

1041

Q9C0B2
SHHAILTPLQTHLTM

PBOV1

76

Q9GZY1
LHTLHMPARVVANSG

ADHFE1

226

Q8IWW8
MSCTIDHTIHQTLAP

GPR68

11

Q15743
PMTETRADVQILHSH

RTL9

31

Q8NET4
HSHSEVLTARPQSME

SYTL2

421

Q9HCH5
MDTQTHSLPITHTQL

TNP2

1

Q05952
PHIMESSHAARILAN

SERAC1

351

Q96JX3
RVSIHSLGHMTPVLS

TINAGL1

241

Q9GZM7
SLRTLSHHASTVQMA

SYNE2

3816

Q8WXH0
NSDASATLPLIMHHS

POU1F1

16

P28069
AFISHHLNMLERPST

TAF2

1056

Q6P1X5
VHSHMTNTRITDPEI

OPLAH

1136

O14841
HLAHSQASMSQSPVR

POU6F2

431

P78424
HISTQIRESPQAMHR

FAM178B

631

Q8IXR5
IHLTSAEHENLRTPM

PSD4

536

Q8NDX1
LPMSIARHNIAGTTH

PTPN12

646

Q05209
VSLETHPTSLNMSTH

PKD1L3

516

Q7Z443
HPTSLNMSTHQLTIT

PKD1L3

521

Q7Z443
TTGLMSHARLPHVAR

PRRC2C

2771

Q9Y520
ISLQSRTGHTHMPSV

PSMD1

746

Q99460
SLHPTVFVQHGRSSM

SPATA31D4

511

Q6ZUB0
HQPLSRARTHTNVMN

WDR20

391

Q8TBZ3
DHMATHLGVSPSRIL

NFATC2IP

291

Q8NCF5
SPSMTVHLHSENGIL

OXCT2

331

Q9BYC2
HRSTLTQASSMTPHS

TRIOBP

236

Q9H2D6
MPRSFLVKTHSSHRV

SNAI3

1

Q3KNW1
MRNSFAHSLSPTLEH

BIRC2

131

Q13490
HMHSQLEHRPSQRSS

EIF4ENIF1

936

Q9NRA8
TDHMAVSRPSVIQHV

ARID5B

741

Q14865
SPHFVSLESRAMHLN

ANKFN1

201

Q8N957
TPGRDMVHHLLSVST

CLP1

356

Q92989
SVRSTLTTHMAVHTG

ZNF665

636

Q9H7R5
SLHPTVFVQHGRSSM

SPATA31D3

511

P0C874
SSTLLRHRLTHMEPQ

ZNF48

371

Q96MX3
HMRFLITHNPTNATL

PTP4A3

16

O75365
VSMTTPHDIRLHGSS

WDFY3

1026

Q8IZQ1
SQCSLLIIHMRSHTG

ZNF568

596

Q3ZCX4
HLAQVPSHTVVARSM

TF

261

P02787
QSFSHQQPSRSHLMR

TRAPPC14

516

Q8WVR3
SHRHSMEISAPVLIS

SH3RF3

396

Q8TEJ3
SSLITHQRIHTGMRP

ZNF256

336

Q9Y2P7
MLSTHHAVASATPVA

SAP130

106

Q9H0E3
TSSLQVMLDHHPVAI

FSBP

136

O95073
PLSSHSDHMTFLQRV

UGT1A1

196

P22309
SSHVFTSHPRMLKRQ

HIVEP3

576

Q5T1R4
HAMTVHPTDLNVRQT

ZNF654

766

Q8IZM8
LHSGLTPHLTMVHSS

PIK3CD

266

O00329
LSTVRTHLSALVNHM

SGSM1

561

Q2NKQ1
THLSALVNHMIVSPD

SGSM1

566

Q2NKQ1
LTRPSLHRSHLNFSM

NUP153

126

P49790
SHVTGLHSLPIVSMT

GTF3C4

416

Q9UKN8
RHHPDVSLCSTMALI

TTC21A

66

Q8NDW8
LAVLSHMLLSFQHSP

USP38

331

Q8NB14
LRTTPSADHHIEAMV

TAS1R2

181

Q8TE23
LTVVSHLHNTSVMSG

PLCH1

1211

Q4KWH8
LAAGSPLAHSRTMHV

ZDHHC14

451

Q8IZN3
PLAHSRTMHVLGLAS

ZDHHC14

456

Q8IZN3
VMETLQRLSPAHAHN

ZSWIM8

1736

A7E2V4
THLPQTLTIHLMRFS

USP41

246

Q3LFD5
PRIASLALHMRSHTG

ZNF569

336

Q5MCW4
QTHFLLSSLHPRMTF

nan

71

Q6ZS52
THSITAHPMVTIRIS

ZZEF1

1871

O43149
THLPQTLTIHLMRFS

USP18

246

Q9UMW8
TTTSKMRIPHSHAFI

ITFG1

196

Q8TB96
VSLSEHHMATLASII

UBR4

676

Q5T4S7
IFSAPSMLERHVVTH

ZBTB40

986

Q9NUA8
QMFRLHLGSTPHNLT

VPS4A

301

Q9UN37