Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nitric-oxide synthase activity	NOS1 NOS3	6.56e-05	3	94	2	GO:0004517
GeneOntologyMolecularFunction	tetrahydrobiopterin binding	NOS1 NOS3	1.31e-04	4	94	2	GO:0034617
GeneOntologyMolecularFunction	kinase binding	KIF20A EZR TPR ERBB2 WWC3 DSP PIK3R1 ANXA5 PKP2 LRBA TRIM22 TBL2 OPA1 EP300	1.70e-04	969	94	14	GO:0019900
GeneOntologyMolecularFunction	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	DSP PKP2	2.17e-04	5	94	2	GO:0086083
GeneOntologyMolecularFunction	ErbB-3 class receptor binding	ERBB2 PIK3R1	3.25e-04	6	94	2	GO:0043125
GeneOntologyBiologicalProcess	cell junction organization	EZR ERBB2 GRIPAP1 TENM3 DSP PIK3R1 FBF1 PKP2 LAMC1 ROCK1 ALOXE3 LRTM2 PPFIA3 OPA1 NEDD4	2.88e-05	974	93	15	GO:0034330
GeneOntologyBiologicalProcess	chordate embryonic development	NCOA6 PRRX1 RPGRIP1L RTL1 E2F7 ERVW-1 EN1 NOS3 OPA1 EP300 RPL13 PRRX2 ERVFRD-1 PCNT	5.28e-05	906	93	14	GO:0043009
GeneOntologyBiologicalProcess	circulatory system development	NCOA6 ERBB2 PRRX1 RPGRIP1L PIK3R6 DSP RTL1 SLIT3 E2F7 PKP2 ROCK1 ERVW-1 NOS3 EP300 PRRX2 ERVFRD-1 PCNT NEDD4	6.78e-05	1442	93	18	GO:0072359
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	NCOA6 PRRX1 RPGRIP1L RTL1 E2F7 ERVW-1 EN1 NOS3 OPA1 EP300 RPL13 PRRX2 ERVFRD-1 PCNT	6.90e-05	929	93	14	GO:0009792
GeneOntologyBiologicalProcess	regulation of intracellular transport	EZR TPR GRIPAP1 PIK3R1 GCC2 EP300 PCNT NEDD4	8.75e-05	314	93	8	GO:0032386
GeneOntologyBiologicalProcess	positive regulation of intracellular transport	EZR TPR PIK3R1 EP300 PCNT NEDD4	9.28e-05	162	93	6	GO:0032388
GeneOntologyBiologicalProcess	negative regulation of interferon-beta production	CACTIN NLRX1 NLRC3	9.57e-05	20	93	3	GO:0032688
GeneOntologyBiologicalProcess	regulation of actin filament-based process	SPTBN5 EZR LMOD3 DSP PIK3R1 PKP2 ROCK1 NOS1 EP300	1.61e-04	438	93	9	GO:0032970
GeneOntologyBiologicalProcess	regulation of intracellular protein transport	TPR GRIPAP1 PIK3R1 GCC2 EP300 PCNT	1.75e-04	182	93	6	GO:0033157
GeneOntologyBiologicalProcess	labyrinthine layer development	NCOA6 RTL1 ERVW-1 ERVFRD-1	2.00e-04	64	93	4	GO:0060711
GeneOntologyBiologicalProcess	embryonic placenta development	NCOA6 RTL1 E2F7 ERVW-1 ERVFRD-1	2.04e-04	119	93	5	GO:0001892
GeneOntologyBiologicalProcess	regulation of protein transport	TPR NCOA6 GRIPAP1 PIK3R1 GCC2 ANXA5 PIWIL4 NOS1 EP300 PCNT	2.15e-04	560	93	10	GO:0051223
GeneOntologyBiologicalProcess	embryonic organ development	NCOA6 PRRX1 RTL1 E2F7 ERVW-1 EN1 EN2 PRRX2 ERVFRD-1 PCNT	2.18e-04	561	93	10	GO:0048568
GeneOntologyBiologicalProcess	regulation of establishment of protein localization	TPR NCOA6 ERBB2 GRIPAP1 PIK3R1 GCC2 ANXA5 PIWIL4 NOS1 EP300 PCNT	2.24e-04	674	93	11	GO:0070201
GeneOntologyBiologicalProcess	neuron development	ERBB2 PRRX1 RPGRIP1L TENM3 SLIT3 LAMC1 ROCK1 APOA4 LRTM2 EN1 EN2 RTN4RL2 TENM2 OPA1 EP300 CUX1 NEDD4	2.63e-04	1463	93	17	GO:0048666
GeneOntologyBiologicalProcess	embryonic brain development	EN1 EN2 PCNT	2.98e-04	29	93	3	GO:1990403
GeneOntologyBiologicalProcess	labyrinthine layer blood vessel development	NCOA6 ERVW-1 ERVFRD-1	2.98e-04	29	93	3	GO:0060716
GeneOntologyBiologicalProcess	positive regulation of guanylate cyclase activity	NOS1 NOS3	2.98e-04	6	93	2	GO:0031284
GeneOntologyBiologicalProcess	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	DSP PKP2	2.98e-04	6	93	2	GO:0086073
GeneOntologyBiologicalProcess	vasculature development	NCOA6 ERBB2 PRRX1 PIK3R6 RTL1 E2F7 ROCK1 ERVW-1 NOS3 PRRX2 ERVFRD-1 PCNT NEDD4	3.98e-04	969	93	13	GO:0001944
GeneOntologyBiologicalProcess	cardiac muscle cell-cardiac muscle cell adhesion	DSP PKP2	4.16e-04	7	93	2	GO:0086042
GeneOntologyBiologicalProcess	myoblast fusion involved in skeletal muscle regeneration	ERVW-1 ERVFRD-1	4.16e-04	7	93	2	GO:0014905
GeneOntologyBiologicalProcess	filopodium assembly	TTYH1 EZR PIK3R1 TENM2	4.28e-04	78	93	4	GO:0046847
GeneOntologyBiologicalProcess	positive regulation of nucleocytoplasmic transport	TPR PIK3R1 EP300 NEDD4	4.49e-04	79	93	4	GO:0046824
GeneOntologyCellularComponent	supramolecular fiber	KIF20A EZR LMOD3 RPGRIP1L NDE1 DSP RTL1 ANXA5 KIF21A FBF1 PKP2 NOS1 OPA1 SMTNL2 PCNT	2.37e-04	1179	94	15	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KIF20A EZR LMOD3 RPGRIP1L NDE1 DSP RTL1 ANXA5 KIF21A FBF1 PKP2 NOS1 OPA1 SMTNL2 PCNT	2.55e-04	1187	94	15	GO:0099081
HumanPheno	Adducted thumb	LMOD3 ERBB2 NDE1 RTL1 SHMT2 TBL2 EP300	9.36e-06	114	35	7	HP:0001181
MousePheno	abnormal syncytiotrophoblast morphology	NCOA6 ERVW-1 ERVFRD-1	5.11e-06	7	75	3	MP:0011531
MousePheno	abnormal placental labyrinth villi morphology	NCOA6 ERVW-1 ERVFRD-1	8.15e-06	8	75	3	MP:0011522
MousePheno	abnormal cerebral blood flow rate	NOS1 NOS3	2.84e-05	2	75	2	MP:0031182
MousePheno	abnormal serotonin level	LRTM2 EN1 EN2 NOS1 NOS3	4.39e-05	73	75	5	MP:0005322
MousePheno	abnormal oculomotor nerve morphology	RPGRIP1L KIF21A EN1	5.17e-05	14	75	3	MP:0001061
MousePheno	abnormal brain blood flow rate	NOS1 NOS3	8.49e-05	3	75	2	MP:0031179
MousePheno	increased trophoblast giant cell number	NCOA6 ERVW-1 ERVFRD-1	1.14e-04	18	75	3	MP:0009397
MousePheno	decreased coronary flow rate	NOS1 NOS3	1.69e-04	4	75	2	MP:0003023
MousePheno	absent oculomotor nerve	RPGRIP1L EN1	1.69e-04	4	75	2	MP:0001062
MousePheno	hemorrhage	ERBB2 RPGRIP1L SLIT3 PKP2 LAMC1 ALOXE3 NOS3 REXO1 OPA1 EP300 PCNT NEDD4	1.99e-04	664	75	12	MP:0001914
Domain	L_dom-like	LMOD3 ERBB2 NLRX1 SLIT3 LRCH4 PODN LRTM2 RTN4RL2 NLRC3 LRRC73	6.56e-06	328	95	10	IPR032675
Domain	Engrail_1_C_sig	EN1 EN2	2.56e-05	2	95	2	PF10525
Domain	Homeobox-engrailed_C-terminal	EN1 EN2	2.56e-05	2	95	2	IPR019549
Domain	Homoebox-engrailed_CS	EN1 EN2	2.56e-05	2	95	2	IPR019737
Domain	ENGRAILED	EN1 EN2	2.56e-05	2	95	2	PS00033
Domain	Prefoldin	TPR DSP KIF21A MPHOSPH9 PPFIA3	3.27e-05	72	95	5	IPR009053
Domain	-	LMOD3 NLRX1 SLIT3 LRCH4 PODN LRTM2 RTN4RL2 NLRC3 LRRC73	3.76e-05	321	95	9	3.80.10.10
Domain	Rhs_assc_core	TENM3 TENM2	7.65e-05	3	95	2	IPR022385
Domain	-	NOS1 NOS3	7.65e-05	3	95	2	3.90.340.10
Domain	NO_synthase	NOS1 NOS3	7.65e-05	3	95	2	PF02898
Domain	Homeodomain_engrailed	EN1 EN2	7.65e-05	3	95	2	IPR000747
Domain	NOS_N	NOS1 NOS3	7.65e-05	3	95	2	IPR004030
Domain	NOS	NOS1 NOS3	7.65e-05	3	95	2	PS60001
Domain	NOS_euk	NOS1 NOS3	7.65e-05	3	95	2	IPR012144
Domain	Tox-GHH_dom	TENM3 TENM2	1.53e-04	4	95	2	IPR028916
Domain	Ten_N	TENM3 TENM2	1.53e-04	4	95	2	IPR009471
Domain	Ten_N	TENM3 TENM2	1.53e-04	4	95	2	PF06484
Domain	TENEURIN_N	TENM3 TENM2	1.53e-04	4	95	2	PS51361
Domain	Tox-GHH	TENM3 TENM2	1.53e-04	4	95	2	PF15636
Domain	tRNA-bd_arm	DSP PPFIA3 CUX1	2.39e-04	24	95	3	IPR010978
Domain	TMEM132	TMEM132C TMEM132B	2.53e-04	5	95	2	PF16070
Domain	TMEM132D_N	TMEM132C TMEM132B	2.53e-04	5	95	2	PF15705
Domain	TMEM132D_C	TMEM132C TMEM132B	2.53e-04	5	95	2	PF15706
Domain	TMEM132_M	TMEM132C TMEM132B	2.53e-04	5	95	2	IPR031437
Domain	TMEM132_C	TMEM132C TMEM132B	2.53e-04	5	95	2	IPR031436
Domain	TMEM132_N	TMEM132C TMEM132B	2.53e-04	5	95	2	IPR031435
Domain	YD	TENM3 TENM2	2.53e-04	5	95	2	IPR006530
Domain	TMEM132	TMEM132C TMEM132B	2.53e-04	5	95	2	IPR026307
Domain	FAD_binding_1	NOS1 NOS3	3.79e-04	6	95	2	PF00667
Domain	FAD-binding_1	NOS1 NOS3	3.79e-04	6	95	2	IPR003097
Domain	-	NOS1 NOS3	3.79e-04	6	95	2	1.20.990.10
Domain	NADPH_Cyt_P450_Rdtase_dom3	NOS1 NOS3	3.79e-04	6	95	2	IPR023173
Domain	Leu-rich_rpt	NLRX1 SLIT3 LRCH4 PODN LRTM2 RTN4RL2 NLRC3	4.67e-04	271	95	7	IPR001611
Domain	TLV_coat	ERVW-1 ERVFRD-1	5.29e-04	7	95	2	PF00429
Domain	FLAVODOXIN_LIKE	NOS1 NOS3	7.03e-04	8	95	2	PS50902
Domain	Flavodoxin/NO_synth	NOS1 NOS3	7.03e-04	8	95	2	IPR008254
Domain	TLV/ENV_coat_polyprotein	ERVW-1 ERVFRD-1	7.03e-04	8	95	2	IPR018154
Domain	Flavdoxin-like	NOS1 NOS3	7.03e-04	8	95	2	IPR001094
Domain	Flavodoxin_1	NOS1 NOS3	7.03e-04	8	95	2	PF00258
Domain	Flavoprotein-like_dom	NOS1 NOS3	1.12e-03	10	95	2	IPR029039
Domain	Flavoprot_Pyr_Nucl_cyt_Rdtase	NOS1 NOS3	1.12e-03	10	95	2	IPR001709
Domain	-	NOS1 NOS3	1.12e-03	10	95	2	3.40.50.360
Domain	RWD	DHX57 RWDD2B	1.37e-03	11	95	2	PF05773
Domain	LRRNT	SLIT3 PODN LRTM2 RTN4RL2	1.57e-03	98	95	4	IPR000372
Domain	LRRNT	SLIT3 PODN LRTM2 RTN4RL2	1.57e-03	98	95	4	SM00013
Domain	OxRdtase_FAD/NAD-bd	NOS1 NOS3	1.63e-03	12	95	2	IPR001433
Domain	NAD_binding_1	NOS1 NOS3	1.63e-03	12	95	2	PF00175
Domain	RWD-domain	DHX57 RWDD2B	1.63e-03	12	95	2	IPR006575
Domain	LRR_8	SLIT3 LRCH4 PODN LRTM2 RTN4RL2	1.81e-03	171	95	5	PF13855
Domain	ANX	ANXA5 ANXA9	1.93e-03	13	95	2	SM00335
Domain	ANNEXIN	ANXA5 ANXA9	1.93e-03	13	95	2	PS00223
Domain	Annexin_repeat_CS	ANXA5 ANXA9	1.93e-03	13	95	2	IPR018252
Domain	Annexin	ANXA5 ANXA9	1.93e-03	13	95	2	PF00191
Domain	NHL	TENM3 TENM2	1.93e-03	13	95	2	PS51125
Domain	Annexin_repeat	ANXA5 ANXA9	1.93e-03	13	95	2	IPR018502
Domain	-	ANXA5 ANXA9	1.93e-03	13	95	2	1.10.220.10
Domain	Leu-rich_rpt_typical-subtyp	SLIT3 LRCH4 PODN LRTM2 RTN4RL2	2.10e-03	177	95	5	IPR003591
Domain	LRR_TYP	SLIT3 LRCH4 PODN LRTM2 RTN4RL2	2.10e-03	177	95	5	SM00369
Domain	Annexin	ANXA5 ANXA9	2.24e-03	14	95	2	IPR001464
Domain	LRRNT	SLIT3 PODN LRTM2	2.48e-03	53	95	3	PF01462
Domain	OAR	PRRX1 PRRX2	2.57e-03	15	95	2	PF03826
Domain	Homeobox_CS	PRRX1 EN1 EN2 CUX1 PRRX2	2.61e-03	186	95	5	IPR017970
Domain	OAR	PRRX1 PRRX2	2.93e-03	16	95	2	PS50803
Domain	OAR_dom	PRRX1 PRRX2	2.93e-03	16	95	2	IPR003654
Domain	CarboxyPept-like_regulatory	TENM3 TENM2	3.31e-03	17	95	2	IPR008969
Domain	ZZ	KCMF1 EP300	3.71e-03	18	95	2	PF00569
Domain	ZF_ZZ_2	KCMF1 EP300	3.71e-03	18	95	2	PS50135
Domain	ZF_ZZ_1	KCMF1 EP300	3.71e-03	18	95	2	PS01357
Domain	Fd_Rdtase_FAD-bd	NOS1 NOS3	4.14e-03	19	95	2	IPR017927
Domain	Znf_ZZ	KCMF1 EP300	4.14e-03	19	95	2	IPR000433
Domain	FAD_FR	NOS1 NOS3	4.14e-03	19	95	2	PS51384
Domain	ZnF_ZZ	KCMF1 EP300	4.14e-03	19	95	2	SM00291
Domain	Riboflavin_synthase-like_b-brl	NOS1 NOS3	4.14e-03	19	95	2	IPR017938
Domain	CH	SPTBN5 LRCH4 SMTNL2	4.43e-03	65	95	3	SM00033
Pubmed	The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.	TENM3 EN1 EN2 TENM2	1.90e-09	7	96	4	10625539
Pubmed	Differential expression of the Tmem132 family genes in the developing mouse nervous system.	TMEM132C EN2 TMEM132B CUX1	9.67e-08	16	96	4	35690356
Pubmed	The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.	TENM3 EN1 TENM2	7.08e-07	7	96	3	12915301
Pubmed	Location of preganglionic neurons is independent of birthdate but is correlated to reelin-producing cells in the spinal cord.	EN1 NOS1 NOS3	1.69e-06	9	96	3	15236237
Pubmed	ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice.	ERBB2 EN1 EN2	1.69e-06	9	96	3	9362461
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TPR DSP GCC2 ZGRF1 ZBTB21 LAMC1 LRBA CUX1 PCNT	2.48e-06	418	96	9	34709266
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	EZR TPR KIF21A ZBTB21 ROCK1 PPFIA3 TMEM132B NOS1 TENM2 OPA1 CUX1 PCNT NEDD4	2.51e-06	963	96	13	28671696
Pubmed	Genetic Evidence That Captured Retroviral Envelope syncytins Contribute to Myoblast Fusion and Muscle Sexual Dimorphism in Mice.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	27589388
Pubmed	The Prx1 homeobox gene is critical for molar tooth morphogenesis.	PRRX1 PRRX2	7.54e-06	2	96	2	16998126
Pubmed	Differential roles of neuronal and endothelial nitric oxide synthases during carrageenan-induced inflammatory hyperalgesia.	NOS1 NOS3	7.54e-06	2	96	2	15350652
Pubmed	Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling.	NOS1 NOS3	7.54e-06	2	96	2	24643800
Pubmed	Characterization of the Engrailed mutant mice as experimental models for Parkinson's disease.	EN1 EN2	7.54e-06	2	96	2	18585948
Pubmed	Intron 4 polymorphism of the endothelial nitric oxide synthase gene is associated with the development of lupus nephritis.	NOS1 NOS3	7.54e-06	2	96	2	15119548
Pubmed	Modulation of the myogenic response in renal blood flow autoregulation by NO depends on endothelial nitric oxide synthase (eNOS), but not neuronal or inducible NOS.	NOS1 NOS3	7.54e-06	2	96	2	21825026
Pubmed	Chronic NOS inhibition actuates endothelial-mesenchymal transformation.	NOS1 NOS3	7.54e-06	2	96	2	16963618
Pubmed	Behavioral, neurochemical, and electrophysiological changes in an early spontaneous mouse model of nigrostriatal degeneration.	EN1 EN2	7.54e-06	2	96	2	21104462
Pubmed	The mouse Engrailed genes: a window into autism.	EN1 EN2	7.54e-06	2	96	2	17055592
Pubmed	Striatal malonate lesions are attenuated in neuronal nitric oxide synthase knockout mice.	NOS1 NOS3	7.54e-06	2	96	2	8667023
Pubmed	nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle.	NOS1 NOS3	7.54e-06	2	96	2	11015578
Pubmed	Regulated coupling of the Neu receptor to phosphatidylinositol 3'-kinase and its release by oncogenic activation.	ERBB2 PIK3R1	7.54e-06	2	96	2	1351056
Pubmed	Reduced expression of both syncytin 1 and syncytin 2 correlates with severity of preeclampsia.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	21493955
Pubmed	Human PRRX1 and PRRX2 genes: cloning, expression, genomic localization, and exclusion as disease genes for Nager syndrome.	PRRX1 PRRX2	7.54e-06	2	96	2	11063257
Pubmed	Renal cortical and medullary blood flow responses to L-NAME and ANG II in wild-type, nNOS null mutant, and eNOS null mutant mice.	NOS1 NOS3	7.54e-06	2	96	2	15961532
Pubmed	Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia.	NOS1 NOS3	7.54e-06	2	96	2	14526232
Pubmed	Nitric oxide synthase polymorphisms and asthma phenotypes in Chinese children.	NOS1 NOS3	7.54e-06	2	96	2	16238787
Pubmed	Sustained nitric oxide (NO)-releasing compound reverses dysregulated NO signal transduction in priapism.	NOS1 NOS3	7.54e-06	2	96	2	24076963
Pubmed	Inducible knockout of Syncytin-A gene leads to an extensive placental vasculature deficiency, implications for preeclampsia.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	28935154
Pubmed	Normal development of the ipsilateral retinocollicular pathway and its disruption in double endothelial and neuronal nitric oxide synthase gene knockout mice.	NOS1 NOS3	7.54e-06	2	96	2	11027405
Pubmed	Neuronal nitric oxide synthase plays a key role in CNS demyelination.	NOS1 NOS3	7.54e-06	2	96	2	17151270
Pubmed	Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism.	NOS1 NOS3	7.54e-06	2	96	2	18305236
Pubmed	Regulation of renin gene expression in kidneys of eNOS- and nNOS-deficient mice.	NOS1 NOS3	7.54e-06	2	96	2	10764216
Pubmed	Repetitive hyperbaric oxygen exposures enhance sensitivity to convulsion by upregulation of eNOS and nNOS.	NOS1 NOS3	7.54e-06	2	96	2	18342297
Pubmed	Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity.	NOS1 NOS3	7.54e-06	2	96	2	7488039
Pubmed	The NOS3 G894T (Glu298Asp) polymorphism is a risk factor for frontotemporal lobar degeneration.	NOS1 NOS3	7.54e-06	2	96	2	19087148
Pubmed	Placental syncytins: Genetic disjunction between the fusogenic and immunosuppressive activity of retroviral envelope proteins.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	18077339
Pubmed	Genetic analysis of NOS isoforms using nNOS and eNOS knockout animals.	NOS1 NOS3	7.54e-06	2	96	2	9932431
Pubmed	Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases.	NOS1 NOS3	7.54e-06	2	96	2	12677017
Pubmed	Zonisamide reduces nigrostriatal dopaminergic neurodegeneration in a mouse genetic model of Parkinson's disease.	EN1 EN2	7.54e-06	2	96	2	25857446
Pubmed	Experience-dependent plasticity acts via GluR1 and a novel neuronal nitric oxide synthase-dependent synaptic mechanism in adult cortex.	NOS1 NOS3	7.54e-06	2	96	2	21813683
Pubmed	P300-mediated NEDD4 acetylation drives ebolavirus VP40 egress by enhancing NEDD4 ligase activity.	EP300 NEDD4	7.54e-06	2	96	2	34111220
Pubmed	Expression, localization, and regulation of NOS in human mast cell lines: effects on leukotriene production.	NOS1 NOS3	7.54e-06	2	96	2	15044250
Pubmed	Cutaneous neuronal nitric oxide is specifically decreased in postural tachycardia syndrome.	NOS1 NOS3	7.54e-06	2	96	2	17660395
Pubmed	Endothelial Nitric Oxide Synthase Is Present in Dendritic Spines of Neurons in Primary Cultures.	NOS1 NOS3	7.54e-06	2	96	2	28725180
Pubmed	Reduced syncytin-1 regulates trophoblast invasion and apoptosis in preeclampsia.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	39121585
Pubmed	Reproductive function in female mice lacking the gene for endothelial nitric oxide synthase.	NOS1 NOS3	7.54e-06	2	96	2	10534440
Pubmed	Analysis of nitric oxide synthase gene polymorphisms in neonatal respiratory distress syndrome among the Chinese Han population.	NOS1 NOS3	7.54e-06	2	96	2	24602444
Pubmed	Combined loss of neuronal and endothelial nitric oxide synthase causes premature mortality and age-related hypertrophic cardiac remodeling in mice.	NOS1 NOS3	7.54e-06	2	96	2	12788381
Pubmed	Dissecting the role of Engrailed in adult dopaminergic neurons--Insights into Parkinson disease pathogenesis.	EN1 EN2	7.54e-06	2	96	2	26459030
Pubmed	Angiotensin II response in afferent arterioles of mice lacking either the endothelial or neuronal isoform of nitric oxide synthase.	NOS1 NOS3	7.54e-06	2	96	2	17959704
Pubmed	Effects of nitric oxide synthase gene knockout on neurotransmitter release in vivo.	NOS1 NOS3	7.54e-06	2	96	2	9692709
Pubmed	Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in Muridae.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	15644441
Pubmed	Myocardial and lymphocytic expression of eNOS and nNOS before and after heart transplantation: relationship to clinical status.	NOS1 NOS3	7.54e-06	2	96	2	23770231
Pubmed	Nitric oxide synthase 1 is partly compensating for nitric oxide synthase 3 deficiency in nitric oxide synthase 3 knock-out mice and is elevated in murine and human cirrhosis.	NOS1 NOS3	7.54e-06	2	96	2	15287858
Pubmed	Interaction between Long Noncoding RNAs and Syncytin-1/Syncytin-2 Genes and Transcripts: How Noncoding RNAs May Affect Pregnancy in Patients with Systemic Lupus Erythematosus.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	36768581
Pubmed	Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance.	NOS1 NOS3	7.54e-06	2	96	2	10905473
Pubmed	Functional characterization of syncytin-A, a newly murine endogenous virus envelope protein. Implication for its fusion mechanism.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	17105734
Pubmed	Nitric oxide synthase gene polymorphisms in children with minimal change nephrotic syndrome.	NOS1 NOS3	7.54e-06	2	96	2	19371282
Pubmed	Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms.	NOS1 NOS3	7.54e-06	2	96	2	11907582
Pubmed	Relative contribution of eNOS and nNOS to endothelium-dependent vasodilation in the mouse aorta.	NOS1 NOS3	7.54e-06	2	96	2	20624383
Pubmed	Chromosomal localization of the human homeo box-containing genes, EN1 and EN2.	EN1 EN2	7.54e-06	2	96	2	2567700
Pubmed	Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice.	NOS1 NOS3	7.54e-06	2	96	2	9486242
Pubmed	Refinement of the ipsilateral retinocollicular projection is disrupted in double endothelial and neuronal nitric oxide synthase gene knockout mice.	NOS1 NOS3	7.54e-06	2	96	2	10727738
Pubmed	Developmental changes in the response of murine cerebellar granule cells to nitric oxide.	NOS1 NOS3	7.54e-06	2	96	2	18406496
Pubmed	Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion.	NOS1 NOS3	7.54e-06	2	96	2	18971208
Pubmed	Does endothelial nitric oxide synthase gene variation play a role in the occurrence of hypertension in pregnancy?	NOS1 NOS3	7.54e-06	2	96	2	12908999
Pubmed	Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels.	NOS1 NOS3	7.54e-06	2	96	2	31259693
Pubmed	Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles.	NOS1 NOS3	7.54e-06	2	96	2	11161004
Pubmed	Neuronal and endothelial nitric oxide synthase gene knockout mice.	NOS1 NOS3	7.54e-06	2	96	2	10559836
Pubmed	Deregulated expression of PAX5 in medulloblastoma.	EN1 EN2	7.54e-06	2	96	2	7777574
Pubmed	The cerebral metabolic consequences of nitric oxide synthase deficiency: glucose utilization in endothelial and neuronal nitric oxide synthase null mice.	NOS1 NOS3	7.54e-06	2	96	2	10027769
Pubmed	Priapism in a Fabry disease mouse model is associated with upregulated penile nNOS and eNOS expression.	NOS1 NOS3	7.54e-06	2	96	2	29110178
Pubmed	Carvedilol induces biased β1 adrenergic receptor-nitric oxide synthase 3-cyclic guanylyl monophosphate signalling to promote cardiac contractility.	NOS1 NOS3	7.54e-06	2	96	2	32956449
Pubmed	Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	21771862
Pubmed	Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection.	NOS1 NOS3	7.54e-06	2	96	2	11904450
Pubmed	Investigation of Prx1 protein expression provides evidence for conservation of cardiac-specific posttranscriptional regulation in vertebrates.	PRRX1 PRRX2	7.54e-06	2	96	2	11747080
Pubmed	Modulation by NO of acetylcholine release in the ileum of wild-type and NOS gene knockout mice.	NOS1 NOS3	7.54e-06	2	96	2	12381527
Pubmed	Contribution of nNOS- and eNOS-derived NO to microvascular smooth muscle NO exposure.	NOS1 NOS3	7.54e-06	2	96	2	15033959
Pubmed	Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions.	EN1 EN2	7.54e-06	2	96	2	1363401
Pubmed	Infarct size and nitric oxide synthase in murine myocardium.	NOS1 NOS3	7.54e-06	2	96	2	10652188
Pubmed	Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway.	EZR PIK3R1	7.54e-06	2	96	2	10377409
Pubmed	Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus.	PRRX1 PRRX2	7.54e-06	2	96	2	10664157
Pubmed	Gastric stasis in neuronal nitric oxide synthase-deficient knockout mice.	NOS1 NOS3	7.54e-06	2	96	2	10982771
Pubmed	Increased alveolar soluble annexin V promotes lung inflammation and fibrosis.	ERBB2 ANXA5	7.54e-06	2	96	2	26160872
Pubmed	Identification of a prx1 limb enhancer.	PRRX1 PRRX2	7.54e-06	2	96	2	10748458
Pubmed	A role for Engrailed-2 in determination of skeletal muscle physiologic properties.	EN1 EN2	7.54e-06	2	96	2	11180961
Pubmed	Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation.	NOS1 NOS3	7.54e-06	2	96	2	26152695
Pubmed	Syncytin-A mediates the formation of syncytiotrophoblast involved in mouse placental development.	ERVW-1 ERVFRD-1	7.54e-06	2	96	2	17762178
Pubmed	Alternatively spliced neuronal nitric oxide synthase mediates penile erection.	NOS1 NOS3	7.54e-06	2	96	2	16488973
Pubmed	The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach.	NOS1 NOS3	7.54e-06	2	96	2	19095954
Pubmed	Neuronal nitric oxide synthase control mechanisms in the cutaneous vasculature of humans in vivo.	NOS1 NOS3	7.54e-06	2	96	2	18048451
Pubmed	Anterior mesendoderm induces mouse Engrailed genes in explant cultures.	EN1 EN2	7.54e-06	2	96	2	8375331
Pubmed	Immunocytochemical distribution of nitric oxide synthase in the human seminal vesicle: a light and electron microscopical study.	NOS1 NOS3	7.54e-06	2	96	2	12802542
Pubmed	Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases.	NOS1 NOS3	7.54e-06	2	96	2	12781920
Pubmed	Comparative analysis of Prx1 and Prx2 expression in mice provides evidence for incomplete compensation.	PRRX1 PRRX2	7.54e-06	2	96	2	11748565
Pubmed	Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS.	NOS1 NOS3	7.54e-06	2	96	2	7518615
Pubmed	Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90.	NOS1 NOS3	7.54e-06	2	96	2	17970747
Pubmed	Physician-diagnosed asthma and acute chest syndrome: associations with NOS polymorphisms.	NOS1 NOS3	7.54e-06	2	96	2	17351927
Pubmed	Establishment of patterned thalamocortical connections does not require nitric oxide synthase.	NOS1 NOS3	7.54e-06	2	96	2	9786989
Pubmed	Endothelial nitric oxide synthase is predominantly involved in angiotensin II modulation of renal vascular resistance and norepinephrine release.	NOS1 NOS3	7.54e-06	2	96	2	18046021
Pubmed	Nitric oxide synthase gene polymorphisms in children with primary nocturnal enuresis: a preliminary study.	NOS1 NOS3	7.54e-06	2	96	2	17365914
GeneFamily	Annexins\|Endogenous ligands	ANXA5 ANXA9	7.98e-04	13	59	2	404
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KCMF1 EP300	1.55e-03	18	59	2	91
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	TTYH1 EZR NCOA6 ATP6V1G2 GCC2 DTX4 KIF21A PKP2 ROCK1 MPHOSPH9 LRBA TENM2 CUX1 MAP3K19 PCNT XPR1	8.64e-06	989	96	16	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____podocyte-2\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM3 RANBP3L DSP PODN ANXA9 SMAD9	3.33e-06	188	96	6	c300accbac71a3bc075fe985543d8a8ead82531b
ToppCell	facs-Skin-nan-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PIK3R6 PODN EN1 PRRX2	3.44e-06	189	96	6	29287525120be2953b76881ba3cfc4379c265e7a
ToppCell	facs-Skin-nan-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PIK3R6 PODN EN1 PRRX2	3.44e-06	189	96	6	7150dad9a92a715487c2d8130fa01b752ea69663
ToppCell	facs-Skin-nan-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PIK3R6 PODN EN1 PRRX2	3.44e-06	189	96	6	6e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP13 TCHH RPGRIP1L ZBTB21 E2F7 PCNT	3.54e-06	190	96	6	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM132C PRRX1 TENM3 SLIT3 PODN PRRX2	3.65e-06	191	96	6	24dc77ee8de01b42559f92721655f4281b114e17
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM132C PRRX1 TENM3 SLIT3 PODN PRRX2	3.88e-06	193	96	6	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 TENM3 SLIT3 PODN LAMC1 PRRX2	3.88e-06	193	96	6	858a186804b36d45957238d3d3eed2768b961641
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 TENM3 SLIT3 PODN LAMC1 PRRX2	3.88e-06	193	96	6	7865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 ANXA5 PODN LAMC1 PRRX2 NEDD4	3.88e-06	193	96	6	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	KIF20A PRRX1 TENM3 ZGRF1 FBXO43 E2F7	4.24e-06	196	96	6	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TMEM132C PRRX1 PIK3R1 SLIT3 PODN LAMC1	4.24e-06	196	96	6	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM132C PRRX1 TENM3 SLIT3 PKP2 EN2	4.62e-06	199	96	6	0cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Mesothelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PRRX1 TENM3 SLIT3 PODN SMTNL2 KCNH5	4.62e-06	199	96	6	ca970114b5aef4518ce580897a62ac88688b2671
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRRX1 SLIT3 SHMT2 PODN PRRX2 SMTNL2	4.76e-06	200	96	6	0e1f9e1622e5a0fd814a1e100f79cbca2e0dbfbb
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KIF20A RANBP3L PODN ANXA9 PRRX2	7.93e-06	126	96	5	83f3540683b3b175b10af059ab8898c46eaccc13
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KIF20A RANBP3L PODN ANXA9 PRRX2	7.93e-06	126	96	5	6d5075d659dac7b96e6857f8485a7d2c4105d685
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KIF20A RANBP3L PODN ANXA9 PRRX2	7.93e-06	126	96	5	fd0001a0f3a0a4421f96fd21813c21cf6f01d40e
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KIF20A RANBP3L PODN ANXA9 PRRX2	7.93e-06	126	96	5	f20424f9baf3c4059cd6b701761e7595400fc47c
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TMEM132C PRRX1 RANBP3L SLIT3 PODN	2.30e-05	157	96	5	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TMEM132C PRRX1 RANBP3L SLIT3 PODN	2.37e-05	158	96	5	e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP13 ERVW-1 NLRC3 MAP3K19 PCNT	2.52e-05	160	96	5	50d4f867d021abcfeb49e6812bcfd5bb57466a31
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP13 ERVW-1 NLRC3 MAP3K19 PCNT	2.52e-05	160	96	5	0f15f895f11dcabb73df79b26bfc4947f38435a7
ToppCell	BL-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP13 TCHH RPGRIP1L E2F7 PRRX2	2.52e-05	160	96	5	3f737451d5713deed20061aa72a9ef77a9a2bc06
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP13 ERVW-1 NLRC3 MAP3K19 PCNT	2.52e-05	160	96	5	7d004bfe42707605b3851cb2319126acda4d4802
ToppCell	Tuft-tuft-1\|World / Class top	USP13 DHX57 ALOXE3 ANXA9 PRRX2	3.18e-05	168	96	5	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	NS-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP13 TCHH RPGRIP1L E2F7 LRRC73	3.36e-05	170	96	5	f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C SLC27A6 PODN PRRX2 KCNH5	4.07e-05	177	96	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C SLC27A6 PODN PRRX2 KCNH5	4.07e-05	177	96	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRRX1 MAN2B2 TENM3 LRRC73 PRRX2	4.07e-05	177	96	5	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20A ZGRF1 FBXO43 E2F7 NOS3	4.07e-05	177	96	5	73ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPTBN5 TENM3 ANXA5 RTN4RL2 CUX1	4.19e-05	178	96	5	a62137d7f5fac16619f8a02844cdb0be7a794bf2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C PRRX1 SLIT3 PODN TMEM132B	4.41e-05	180	96	5	c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C PRRX1 SLIT3 PODN TMEM132B	4.41e-05	180	96	5	32c6a3886428d82fb4355d987c6d2645f333447b
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P1-P1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC27A6 EN1 EN2 CHST3	4.51e-05	91	96	4	83564e9e4122c176a28c30b0c2546c82185ddaa6
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC27A6 EN1 EN2 CHST3	4.51e-05	91	96	4	ff6022b23e9bd8af24bcb658ae2b48eae6bf1e28
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Pdgfa_(Pdgfa)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC27A6 EN1 EN2 CHST3	4.51e-05	91	96	4	4d84281e8e3236c687b910cd76de836b70dafdb7
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TMEM132C RANBP3L SLIT3 LAMC1 TENM2	4.53e-05	181	96	5	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	USP13 SLC9C1 PKP2 TENM2 XPR1	4.65e-05	182	96	5	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	21-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	USP13 TCHH RPGRIP1L ZBTB21 E2F7	4.65e-05	182	96	5	6e35892fa959ee31591850ded8f1088195ddeb01
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PODN EN1 PRRX2	4.90e-05	184	96	5	fea4fe648e9749177d0783443dc26a7df5807883
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PODN EN1 PRRX2	4.90e-05	184	96	5	96a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PODN EN1 PRRX2	4.90e-05	184	96	5	780eb72da43527f0c72effac3423ec7384f05f20
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PRRX1 TENM3 CHST3 SMAD9 NEDD4	5.03e-05	185	96	5	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PODN EN1 PRRX2	5.03e-05	185	96	5	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PODN EN1 PRRX2	5.03e-05	185	96	5	049d793d043d5d434f143025de49dd210d18756c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	TMEM132C PRRX1 SLIT3 PODN PRRX2	5.03e-05	185	96	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	facs-Skin-nan-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 PODN EN1 PRRX2	5.03e-05	185	96	5	63200c42565eea596f9b00728e70e544b8d50a7f
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PRRX1 TENM3 CHST3 SMAD9 NEDD4	5.03e-05	185	96	5	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	KIF20A ZGRF1 FBXO43 E2F7 LAMC1	5.16e-05	186	96	5	5cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20A TENM3 ZGRF1 FBXO43 E2F7	5.29e-05	187	96	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20A TENM3 ZGRF1 FBXO43 E2F7	5.29e-05	187	96	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH1 EN1 RTN4RL2 CUX1 RPL13	5.29e-05	187	96	5	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 SLIT3 PODN LAMC1 PRRX2	5.56e-05	189	96	5	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM132C PRRX1 SLIT3 PODN LAMC1	5.56e-05	189	96	5	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 SLIT3 PODN LAMC1 PRRX2	5.56e-05	189	96	5	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRRX1 TENM3 ANXA5 SLIT3 LAMC1	5.70e-05	190	96	5	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	NS-critical-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP13 TCHH ZBTB21 E2F7 PCNT	5.70e-05	190	96	5	7be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte-7\|World / Primary Cells by Cluster	TTYH1 EZR RANBP3L ANXA5 TMEM132B	5.70e-05	190	96	5	8f1c490dd8e5f80382f5294fd1aa8cba4c3c647f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRRX1 TENM3 ANXA5 SLIT3 LAMC1	5.70e-05	190	96	5	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte\|World / Primary Cells by Cluster	TTYH1 EZR RANBP3L ANXA5 TMEM132B	5.70e-05	190	96	5	7dbfd543398c63cbe1e68b54bcb5e2291f521935
ToppCell	droplet-Mammary_Gland-nan-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 ANXA5 SLIT3 LAMC1 NEDD4	5.85e-05	191	96	5	8022059e434fd411dc539819f969bd4f94861281
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM132C SLIT3 PODN LAMC1 SMTNL2	5.85e-05	191	96	5	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 SLIT3 PODN LAMC1 PRRX2	5.99e-05	192	96	5	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	USP13 KIF21A PKP2 TENM2 XPR1	5.99e-05	192	96	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TTYH1 PRRX1 TENM3 TENM2 PRRX2	5.99e-05	192	96	5	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRRX1 SLIT3 PODN LAMC1 PRRX2	5.99e-05	192	96	5	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 SLIT3 PODN LAMC1 PRRX2	5.99e-05	192	96	5	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRRX1 SLIT3 PODN LAMC1 PRRX2	5.99e-05	192	96	5	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRRX1 SLIT3 PODN LAMC1 PRRX2	5.99e-05	192	96	5	f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 SLIT3 LAMC1 EN1 PRRX2	6.14e-05	193	96	5	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	USP13 KIF21A PKP2 TENM2 XPR1	6.14e-05	193	96	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 SLIT3 LAMC1 EN1 PRRX2	6.14e-05	193	96	5	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	Club_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	EZR ERBB2 DSP DTX4 LRCH4	6.14e-05	193	96	5	6582c0367052b9d10fb629c383ee0c55872afd2d
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132C PRRX1 SLIT3 PODN LAMC1	6.14e-05	193	96	5	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TMEM132C PIK3R1 SLIT3 LAMC1 TENM2	6.14e-05	193	96	5	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	PRRX1 TENM3 RANBP3L SLIT3 TENM2	6.14e-05	193	96	5	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	18-Distal-Mesenchymal-Cartilage\|Distal / Age, Tissue, Lineage and Cell class	TTYH1 PRRX1 TENM3 RPL13 PRRX2	6.14e-05	193	96	5	52f3d1bb8d8ca91ba12439d46392f377928ff8f8
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRRX1 TENM3 SLIT3 PODN PRRX2	6.14e-05	193	96	5	025836c5c5a711e477c326559e618e47cae42d11
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRX1 SLIT3 LAMC1 EN1 PRRX2	6.14e-05	193	96	5	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	USP13 TCHH RPGRIP1L ZBTB21 E2F7	6.30e-05	194	96	5	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	USP13 TCHH ZBTB21 E2F7 PCNT	6.30e-05	194	96	5	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRRX1 PIK3R1 SLIT3 PODN LAMC1	6.45e-05	195	96	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	USP13 KIF21A PKP2 TENM2 XPR1	6.45e-05	195	96	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM132C PRRX1 SLIT3 PODN LAMC1	6.45e-05	195	96	5	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	droplet-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR ANXA5 KIF21A RPL13 NEDD4	6.45e-05	195	96	5	a31a8c0e8e666acfc6737fa2c54ebd6f35605520
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KIF20A PRRX1 ZGRF1 FBXO43 E2F7	6.61e-05	196	96	5	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM132C PRRX1 RANBP3L SLIT3 PODN	6.77e-05	197	96	5	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-E\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	PRRX1 PIK3R1 GCC2 PODN SMAD9	6.77e-05	197	96	5	9b1c1d72c5a8c90d71ae31e4c198d2276872eaa0
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP6V1G2 KIF21A SLIT3 AMER3 XPR1	6.77e-05	197	96	5	27c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRRX1 PODN LAMC1 EN1 PRRX2	6.77e-05	197	96	5	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM132C PRRX1 TENM3 RANBP3L PODN	6.77e-05	197	96	5	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EZR DSP OSBPL6 PKP2 CUX1	6.77e-05	197	96	5	b0fb5774525ba05f60c635d42f14bb8d79bff17c
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM132C PRRX1 SLIT3 PODN PRRX2	6.77e-05	197	96	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EZR DSP OSBPL6 PKP2 CUX1	6.77e-05	197	96	5	bbb7c106d5b96b8e95aeb3e5c293e104fceea234
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF20A USP13 OSBPL6 E2F7 DHX57	6.77e-05	197	96	5	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	KIF20A USP13 TCHH FBXO43 E2F7	6.77e-05	197	96	5	1ffbbe44db0fd3ebd91ad16ab0b91153de5d7c6d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRRX1 DSP LAMC1 TENM2 PRRX2	6.93e-05	198	96	5	5cfd1c030c0940136a397b5a4b5d6ecbaecf72eb
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRRX1 TENM3 SLIT3 PODN LAMC1	6.93e-05	198	96	5	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRRX1 DSP LAMC1 TENM2 PRRX2	6.93e-05	198	96	5	ff6d9455ebfe965cc6f48197172c0ebd3bddde81
Drug	AC1L9M2J	ERBB2 PIK3R1 NOS3 OPA1 EP300	1.75e-05	76	96	5	CID000448538
Drug	L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide	NOS1 NOS3	1.76e-05	2	96	2	DB01821
Drug	S-Ethyl-N-Phenyl-Isothiourea	NOS1 NOS3	1.76e-05	2	96	2	DB03707
Drug	L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide	NOS1 NOS3	1.76e-05	2	96	2	DB02077
Drug	N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine	NOS1 NOS3	1.76e-05	2	96	2	DB02027
Drug	N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE	NOS1 NOS3	1.76e-05	2	96	2	DB08018
Drug	N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine	NOS1 NOS3	1.76e-05	2	96	2	DB08019
Drug	Nitroarginine	NOS1 NOS3	1.76e-05	2	96	2	DB04223
Drug	Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; PC3; HT_HG-U133A	CACTIN NDE1 PIK3R1 NLRX1 DHX57 PPFIA3 CHST3	2.10e-05	198	96	7	6297_DN
Drug	GEA 3162	ANXA5 NOS1 NOS3	2.56e-05	14	96	3	CID003035443
Drug	N-(3-(Aminomethyl)Benzyl)Acetamidine	NOS1 NOS3	5.26e-05	3	96	2	DB02044
Drug	4-methylpyrimidine	DSP NOS3	5.26e-05	3	96	2	CID000018922
Drug	3-Bromo-7-Nitroindazole	NOS1 NOS3	5.26e-05	3	96	2	DB01997
Drug	dihydrochloride	ZBTB21 ROCK1 APOA4 LRBA NOS1 NOS3	5.83e-05	159	96	6	CID000070978
Drug	MolPort-016-580-972	PIK3R1 ANXA5 EP300 CUX1	6.37e-05	51	96	4	CID009938589
Disease	portal hypertension (implicated_via_orthology)	PIK3R1 NOS1 NOS3	2.83e-05	19	93	3	DOID:10762 (implicated_via_orthology)
Disease	Hypertriglyceridemia	LAMC1 APOA4 TBL2	2.83e-05	19	93	3	EFO_0004211
Disease	major depressive disorder (biomarker_via_orthology)	APOA4 NOS1	2.94e-05	3	93	2	DOID:1470 (biomarker_via_orthology)
Disease	Intestinal Perforation	NOS1 NOS3	2.94e-05	3	93	2	C0021845
Disease	lip morphology measurement	PRRX1 RPGRIP1L PIK3R1 GCC2 TENM2 SACM1L	3.06e-05	189	93	6	EFO_0007845
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	SLIT3 NOS3 EP300	5.85e-05	24	93	3	DOID:3827 (biomarker_via_orthology)
Disease	lissencephaly (implicated_via_orthology)	NDE1 NOS1 NOS3	8.39e-05	27	93	3	DOID:0050453 (implicated_via_orthology)
Disease	Paroxysmal atrial fibrillation	PRRX1 SLC27A6 SLIT3 PKP2 NOS3	1.38e-04	156	93	5	C0235480
Disease	familial atrial fibrillation	PRRX1 SLC27A6 SLIT3 PKP2 NOS3	1.38e-04	156	93	5	C3468561
Disease	Persistent atrial fibrillation	PRRX1 SLC27A6 SLIT3 PKP2 NOS3	1.38e-04	156	93	5	C2585653
Disease	Atrial Fibrillation	PRRX1 SLC27A6 SLIT3 PKP2 NOS3	1.56e-04	160	93	5	C0004238
Disease	Arrhythmogenic right ventricular cardiomyopathy	DSP PKP2	2.04e-04	7	93	2	cv:C0349788
Disease	Cerebellar Diseases	RPGRIP1L NOS1	2.04e-04	7	93	2	C0007760
Disease	Adenocarcinoma of large intestine	ERBB2 PIK3R1 EP300 CUX1	2.46e-04	96	93	4	C1319315
Disease	congestive heart failure (biomarker_via_orthology)	ERBB2 NOS1 NOS3 OPA1	3.72e-04	107	93	4	DOID:6000 (biomarker_via_orthology)
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	DSP PKP2	4.35e-04	10	93	2	DOID:0050431 (is_implicated_in)
Disease	Oligospermia	PIWIL4 NOS3	6.35e-04	12	93	2	C0028960
Disease	outer ear morphology trait	LRBA CUX1	6.35e-04	12	93	2	EFO_0007664
Disease	Malignant Neoplasms	ERBB2 PIK3R1 NOS3 CUX1	7.32e-04	128	93	4	C0006826
Disease	cardiomyopathy (biomarker_via_orthology)	NOS1 NOS3	7.49e-04	13	93	2	DOID:0050700 (biomarker_via_orthology)
Disease	Carcinogenesis	ERBB2 CUX1	7.49e-04	13	93	2	C0596263
Disease	hypertension (biomarker_via_orthology)	PIK3R1 NOS1 NOS3 OPA1 EP300	7.73e-04	227	93	5	DOID:10763 (biomarker_via_orthology)
Disease	Alzheimer's disease (is_implicated_in)	PIK3R1 APOA4 NOS1 NOS3	8.21e-04	132	93	4	DOID:10652 (is_implicated_in)
Disease	mean arterial pressure	GRIPAP1 MPHOSPH9 LRBA NOS3 REXO1 RBM43 TFE3	1.03e-03	499	93	7	EFO_0006340
Disease	transient cerebral ischemia (implicated_via_orthology)	NOS1 NOS3 OPA1	1.10e-03	64	93	3	DOID:224 (implicated_via_orthology)
Disease	Pre-Eclampsia	ANXA5 NOS3	1.15e-03	16	93	2	C0032914
Disease	diabetic retinopathy (implicated_via_orthology)	NOS3 EP300	1.15e-03	16	93	2	DOID:8947 (implicated_via_orthology)
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	NCOA6 PIK3R1 NOS1 NOS3	1.22e-03	147	93	4	DOID:9352 (biomarker_via_orthology)
Disease	Parkinson's disease (is_marker_for)	ERBB2 ANXA5 NOS1	1.25e-03	67	93	3	DOID:14330 (is_marker_for)
Disease	schizophrenia, irritable bowel syndrome	MPHOSPH9 EP300	1.30e-03	17	93	2	EFO_0000555, MONDO_0005090
Disease	schizophrenia (implicated_via_orthology)	SHMT2 NOS1 CHST3	1.31e-03	68	93	3	DOID:5419 (implicated_via_orthology)
Disease	Alzheimer's disease (is_marker_for)	ANXA5 NOS1 NOS3 OPA1 EP300	1.34e-03	257	93	5	DOID:10652 (is_marker_for)
Disease	autism spectrum disorder (implicated_via_orthology)	PKP2 LAMC1 LRBA EN2	1.38e-03	152	93	4	DOID:0060041 (implicated_via_orthology)
Disease	myocardial infarction (biomarker_via_orthology)	SLC27A6 ANXA5 NOS3 OPA1	1.67e-03	160	93	4	DOID:5844 (biomarker_via_orthology)
Disease	epilepsy (implicated_via_orthology)	NDE1 NOS1 NOS3 KCNH5	1.79e-03	163	93	4	DOID:1826 (implicated_via_orthology)
Disease	Schizophrenia	NDE1 SLIT3 APOA4 ERVW-1 EN1 EN2 NOS1 OPA1 PCNT	1.89e-03	883	93	9	C0036341
Disease	Left Ventricle Remodeling	NOS1 OPA1	1.98e-03	21	93	2	C0600520
Disease	Ventricular Remodeling	NOS1 OPA1	1.98e-03	21	93	2	C0600519
Disease	level of Phosphatidylcholine (16:1_18:2) in blood serum	ROCK1 ESCO1	1.98e-03	21	93	2	OBA_2045083
Disease	phosphatidylcholine measurement	NDE1 ZGRF1 APOA4 ESCO1 PRRX2	2.08e-03	284	93	5	EFO_0010226
Disease	impotence (biomarker_via_orthology)	NOS1 NOS3	2.18e-03	22	93	2	DOID:1875 (biomarker_via_orthology)
Disease	diacylglycerol 34:2 measurement	APOA4 LRTM2	2.81e-03	25	93	2	EFO_0010353
Disease	colorectal cancer	LAMC1 PIWIL4 LRBA NOS1 PCNT CHST3 SMAD9	3.02e-03	604	93	7	MONDO_0005575
Disease	osteoarthritis, hip	PIK3R1 EP300 CHST3	3.11e-03	92	93	3	EFO_1000786

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSQQRNRERVLAQLL	ATP6V1G2	86	O95670
FQQRLTLSQRALANI	TTYH1	311	Q9H313
DSVNRSVRQQQRALL	AMER3	311	Q8N944
LLRQLSLEQSFQRSQ	CCDC185	446	Q8N715
NNQLALTLIDTNRSR	ERBB2	176	P04626
VSQQALQNLLRTLRS	EP300	2046	Q09472
SLSSLTNILDRQRSQ	CFAP92	326	Q9ULG3
LLTSRSNAQRQEISA	ANXA5	41	P08758
TLNRTNLQRLAIAQS	DTX4	291	Q9Y2E6
NSSRIANRRIANSNN	ATXN7L3	111	Q14CW9
STQRLFLQNNLIRTL	RTN4RL2	61	Q86UN3
LQRSNNSLASVRTLV	RBM43	196	Q6ZSC3
SETSQRLANLRQRVE	SHMT2	476	P34897
RNRTTFNSSQLQALE	PRRX2	106	Q99811
LSSLRDLNVRRNQLS	LRCH4	181	O75427
QLRTQVSTQAEQLRR	APOA4	141	P06727
RLETLNLQNNRLTSR	PODN	121	Q7Z5L7
QLQAQRAFTTRRQIS	NEDD4	656	P46934
NSSLRRLNLQENSLG	NLRC3	1001	Q7RTR2
SLLQLREQQATDQRS	RPGRIP1L	246	Q68CZ1
LRENRSITTLNIESN	LMOD3	306	Q0VAK6
QSRLAQISRDIQERN	ALOXE3	676	Q9BYJ1
SNQETLNLREQLSRR	PPFIA3	191	O75145
RLTRALTNSRSVLQQ	KCNH5	151	Q8NCM2
RSLQSENAALRISNS	CUX1	401	Q13948
QQRQKRLNSASQRSS	MPHOSPH9	791	Q99550
NNSRENRRSLLQCSV	LRBA	851	P50851
RQLISRNFQERTQQD	ANXA9	76	O76027
QNQRFSAEVLSSLRQ	NLRX1	686	Q86UT6
RTQSSSNLAELRQLL	PIK3R1	151	P27986
QRRQTLAQELSLNES	EN1	331	Q05925
SLSQALNQNAELRSR	OSBPL6	426	Q9BZF3
SRRAQELALLQSRQQ	PCNT	286	O95613
RVSAARLLSRQNLQS	NOS1	996	P29475
SRIRTQSFSLQERQL	NOS3	1171	P29474
ERLRILAQSNNQQLR	NCOA6	106	Q14686
ANTLRQQLTNTEVRR	OPA1	891	O60313
LQLLNRSALRSVQAQ	FBXO43	571	Q4G163
LSLAQQRLQLDRARQ	FBF1	1031	Q8TES7
NQSRNTSSAQRRLEI	E2F7	891	Q96AV8
QLQSNSLFNNRRSNR	DHX57	866	Q6P158
ELRSQLQISNNRTLE	DSP	1751	P15924
SSQQSLKNLRERRNT	GCC2	1486	Q8IWJ2
LNREAVLRTSTNLNS	MAN2B2	711	Q9Y2E5
QQLETARNATRRTNT	KCMF1	246	Q9P0J7
DRLQRVNNTLSSQIS	LAMC1	1101	P11047
AAALSQQQSLQERLR	CACTIN	131	Q8WUQ7
EQLNRRSQRLQQLTE	ESCO1	116	Q5FWF5
RVQRQLLTLSSELSQ	EZR	526	P15311
EQRRQSLAQELSLNE	EN2	271	P19622
DLNSQLQESLRANSR	GRIPAP1	386	Q4V328
TNVIQSLLARRSLQA	SACM1L	396	Q9NTJ5
DRDISNNQILTTSLR	MAP3K19	821	Q56UN5
RRRNKSTESLQANVQ	RPL13	101	P26373
QRNTAARQTLLLASR	RTL1	1006	A6NKG5
LRAQQAQRASASLLQ	REXO1	696	Q8N1G1
QLNSLAAVVLQNRRA	ERVW-1	371	Q9UQF0
NRRLLSAQIASYQRQ	SLC9C1	516	Q4G0N8
ANQDLTRNSSLQARV	TMEM132B	56	Q14DG7
EANQDLLRNSSLQAR	TMEM132C	66	Q8N3T6
TNLTELQLRNNSIRT	LRTM2	116	Q8N967
FRTNNIQIQSRDQRL	PIK3R6	671	Q5UE93
QQRLARLVDNIQRNT	PIWIL4	411	Q7Z3Z4
SANSLNRNSLTNRRS	TENM2	266	Q9NT68
LATRLVQTARNSQLD	MSH4	891	O15457
AEAARSQALQQRLLQ	SPTBN5	406	Q9NRC6
LSNVNRNSTIENTRR	SMAD9	316	O15198
AFSQLQSRLRNLSLQ	CHST3	86	Q7LGC8
RDLEILTLNNNNISR	SLIT3	181	O75094
QRRFATLQNELQSSL	XPR1	81	Q9UBH6
SSQAQQVIKRNLRSR	ZBTB21	651	Q9ULJ3
QARIQSRRITLANCQ	nan	51	Q96MF0
SRQRSLEQANRSLQL	TFE3	411	P19532
NIRQLLNQASSLRER	ERVFRD-1	451	P60508
LQRASTALSNEQQAR	TPR	1051	P12270
RASQQINALRSEITR	KIF21A	381	Q7Z4S6
RSQRLAASASTQQLQ	KIF20A	676	O95235
LLLRNNSIQNRQLLA	STX16	11	O14662
ENLSRARISVQLSTN	RANBP3L	171	Q86VV4
DNQRLQAQLERLTRQ	SMTNL2	66	Q2TAL5
TSLNRNSLTNRRNQS	TENM3	201	Q9P273
RSVLLSRSQQTQLNT	RWDD2B	121	P57060
SQLESLNRELQERNR	ROCK1	576	Q13464
ENENLQRLSLLSRTQ	ZGRF1	1051	Q86YA3
RNRTTFNSSQLQALE	PRRX1	96	P54821
NTNIRSNSLLNCIRA	SLC27A6	136	Q9Y2P4
TLRLESVDLQSSRNN	TGM7	6	Q96PF1
RQLEDSQLRDRQSQQ	TCHH	1251	Q07283
QRQDASTLISDLQRR	TRIM22	226	Q8IYM9
SLLRNLSRNLSLQNE	PKP2	751	Q99959
RRRKQLFTLQTVNSN	USP11	711	P51784
LKRASNESTRQRLQQ	TBL2	416	Q9Y4P3
AIQALRATNNNLERA	USP13	746	Q92995
LDLQASRTRQRQLNE	WWC3	971	Q9ULE0
RLQDLTNQTSLDVQR	VWA5B1	691	Q5TIE3
QLAEALRTNRSIQSL	LRRC73	76	Q5JTD7
QIETRNRDLLSENNR	NDE1	56	Q9NXR1