Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	deaminase binding	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	8.09e-10	4	108	4	GO:1990827
GeneOntologyMolecularFunction	N6-methyladenosine-containing RNA reader activity	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.06e-06	15	108	4	GO:1990247
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SP1 ZNF486 ZNF48 FEZF2 MTF2 ESR2 NSD1 ZNF195 ZNF75CP ZFP37 ZNF404 ZNF23 ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	2.68e-06	1459	108	23	GO:0000977
GeneOntologyMolecularFunction	protein-RNA adaptor activity	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	7.91e-06	24	108	4	GO:0140517
GeneOntologyMolecularFunction	telomerase RNA binding	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.38e-06	25	108	4	GO:0070034
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SP1 ZNF486 ZNF48 FEZF2 ESR2 ZNF195 ZNF75CP ZFP37 ZNF404 ZNF23 ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	1.91e-05	1412	108	21	GO:0000981
GeneOntologyMolecularFunction	hemoglobin beta binding	HBB HBD	2.90e-05	2	108	2	GO:0031722
GeneOntologyMolecularFunction	poly(U) RNA binding	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	3.31e-05	34	108	4	GO:0008266
GeneOntologyMolecularFunction	poly-pyrimidine tract binding	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	5.75e-05	39	108	4	GO:0008187
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SP1 ZNF486 ZNF48 FEZF2 ESR2 NSD1 ZNF195 ZNF75CP ZNF23 ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF221 ZNF30 ZNF107 ZNF418 ZNF445	1.17e-04	1244	108	18	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SP1 ZNF486 ZNF48 FEZF2 ESR2 NSD1 ZNF195 ZNF75CP ZNF23 ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF221 ZNF30 ZNF107 ZNF418 ZNF445	1.53e-04	1271	108	18	GO:0000987
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	RPS6KA4 HTATIP2 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 PRKDC STK25	1.54e-04	446	108	10	GO:0004674
GeneOntologyMolecularFunction	protein serine kinase activity	RPS6KA4 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 PRKDC STK25	1.58e-04	363	108	9	GO:0106310
GeneOntologyMolecularFunction	hemoglobin alpha binding	HBB HBD	2.87e-04	5	108	2	GO:0031721
GeneOntologyMolecularFunction	single-stranded RNA binding	HNRNPCL1 HNRNPC DDX1 HNRNPCL3 HNRNPCL2	3.43e-04	111	108	5	GO:0003727
GeneOntologyMolecularFunction	haptoglobin binding	HBB HBD	1.27e-03	10	108	2	GO:0031720
GeneOntologyMolecularFunction	protein kinase activity	RPS6KA4 HTATIP2 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 PRKDC STK25	1.54e-03	600	108	10	GO:0004672
GeneOntologyMolecularFunction	hemoglobin binding	HBB HBD	1.54e-03	11	108	2	GO:0030492
GeneOntologyMolecularFunction	U3 snoRNA binding	TSR1 PRKDC	1.54e-03	11	108	2	GO:0034511
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CERK RPS6KA4 HTATIP2 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 PRKDC STK25	1.59e-03	709	108	11	GO:0016773
GeneOntologyMolecularFunction	co-SMAD binding	USP9X USP9Y	1.85e-03	12	108	2	GO:0070410
GeneOntologyMolecularFunction	chromatin binding	MCM8 FEZF2 MTF2 ESR2 NSD1 REPIN1 HNRNPC DDX1 CHD5 NIPBL ZNF445	2.20e-03	739	108	11	GO:0003682
GeneOntologyMolecularFunction	oxygen carrier activity	HBB HBD	2.53e-03	14	108	2	GO:0005344
GeneOntologyMolecularFunction	5S rRNA binding	GTF3A RPL7	2.53e-03	14	108	2	GO:0008097
GeneOntologyMolecularFunction	sodium channel activity	SCN11A HCN1 GRIA2	2.80e-03	52	108	3	GO:0005272
GeneOntologyMolecularFunction	kinase activity	CERK RPS6KA4 HTATIP2 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 PRKDC STK25	2.84e-03	764	108	11	GO:0016301
GeneOntologyBiologicalProcess	negative regulation of mRNA modification	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.81e-09	6	106	4	GO:0090367
GeneOntologyBiologicalProcess	regulation of mRNA modification	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	2.28e-08	7	106	4	GO:0090365
GeneOntologyBiologicalProcess	negative regulation of telomere maintenance via telomerase	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	7.67e-06	25	106	4	GO:0032211
GeneOntologyBiologicalProcess	mRNA modification	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.03e-06	26	106	4	GO:0016556
GeneOntologyBiologicalProcess	3'-UTR-mediated mRNA stabilization	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.86e-05	31	106	4	GO:0070935
GeneOntologyBiologicalProcess	negative regulation of telomere maintenance via telomere lengthening	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	2.40e-05	33	106	4	GO:1904357
GeneOntologyBiologicalProcess	mRNA stabilization	HNRNPCL1 LARP1 HNRNPC HNRNPCL3 HNRNPCL2	4.80e-05	77	106	5	GO:0048255
GeneOntologyBiologicalProcess	regulation of translational initiation by eIF2 alpha phosphorylation	EIF2AK4 HBB HBD	5.74e-05	15	106	3	GO:0010998
GeneOntologyBiologicalProcess	negative regulation of telomere maintenance	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	6.35e-05	42	106	4	GO:0032205
GeneOntologyBiologicalProcess	negative regulation of DNA biosynthetic process	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	6.97e-05	43	106	4	GO:2000279
GeneOntologyBiologicalProcess	negative regulation of mRNA catabolic process	HNRNPCL1 LARP1 HNRNPC HNRNPCL3 HNRNPCL2	8.62e-05	87	106	5	GO:1902373
GeneOntologyBiologicalProcess	RNA stabilization	HNRNPCL1 LARP1 HNRNPC HNRNPCL3 HNRNPCL2	9.10e-05	88	106	5	GO:0043489
GeneOntologyBiologicalProcess	regulation of translational initiation in response to stress	EIF2AK4 HBB HBD	1.02e-04	18	106	3	GO:0043558
GeneOntologyBiologicalProcess	regulation of translational initiation	LARP1 DDX1 EIF2AK4 HBB HBD	1.07e-04	91	106	5	GO:0006446
GeneOntologyBiologicalProcess	regulation of eIF2 alpha phosphorylation by heme	HBB HBD	1.56e-04	4	106	2	GO:0010999
GeneOntologyBiologicalProcess	negative regulation of RNA catabolic process	HNRNPCL1 LARP1 HNRNPC HNRNPCL3 HNRNPCL2	1.75e-04	101	106	5	GO:1902369
GeneOntologyBiologicalProcess	chromosome organization	HNRNPCL1 MCM8 MCMDC2 CIT HNRNPC DDX1 HNRNPCL3 BRCA2 CDK5RAP2 PRKDC NIPBL HNRNPCL2	2.11e-04	686	106	12	GO:0051276
GeneOntologyBiologicalProcess	negative regulation of chromosome organization	HNRNPCL1 HNRNPC HNRNPCL3 CDK5RAP2 HNRNPCL2	2.29e-04	107	106	5	GO:2001251
GeneOntologyBiologicalProcess	telomere maintenance	HNRNPCL1 HNRNPC HNRNPCL3 BRCA2 PRKDC HNRNPCL2	2.33e-04	168	106	6	GO:0000723
GeneOntologyBiologicalProcess	regulation of telomere maintenance via telomerase	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	2.58e-04	60	106	4	GO:0032210
GeneOntologyBiologicalProcess	negative regulation of mRNA metabolic process	HNRNPCL1 LARP1 HNRNPC HNRNPCL3 HNRNPCL2	3.20e-04	115	106	5	GO:1903312
GeneOntologyBiologicalProcess	regulation of translation in response to stress	EIF2AK4 HBB HBD	3.94e-04	28	106	3	GO:0043555
GeneOntologyBiologicalProcess	regulation of telomere maintenance via telomere lengthening	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	4.41e-04	69	106	4	GO:1904356
GeneOntologyBiologicalProcess	telomere organization	HNRNPCL1 HNRNPC HNRNPCL3 BRCA2 PRKDC HNRNPCL2	5.73e-04	199	106	6	GO:0032200
GeneOntologyBiologicalProcess	translational initiation	LARP1 DDX1 EIF2AK4 HBB HBD	6.01e-04	132	106	5	GO:0006413
GeneOntologyCellularComponent	nucleoplasmic periphery of the nuclear pore complex	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.30e-09	6	106	4	GO:1990826
GeneOntologyCellularComponent	telomerase holoenzyme complex	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	7.28e-06	25	106	4	GO:0005697
GeneOntologyCellularComponent	pronucleus	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.16e-05	28	106	4	GO:0045120
Domain	-	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	1.58e-10	679	105	21	3.30.160.60
Domain	zf-C2H2	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	2.29e-10	693	105	21	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	2.35e-10	694	105	21	IPR013087
Domain	ZINC_FINGER_C2H2_2	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	1.72e-09	775	105	21	PS50157
Domain	ZINC_FINGER_C2H2_1	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	1.80e-09	777	105	21	PS00028
Domain	zf-C2H2_6	ZNF486 ZNF48 FEZF2 ZNF195 ZFP37 ZNF404 ZNF253 ZNF727 ZNF799 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	2.51e-09	314	105	14	PF13912
Domain	Znf_C2H2-like	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	2.77e-09	796	105	21	IPR015880
Domain	Znf_C2H2	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	3.38e-09	805	105	21	IPR007087
Domain	ZnF_C2H2	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	3.61e-09	808	105	21	SM00355
Domain	KRAB	ZNF486 ZNF195 ZFP37 ZNF404 ZNF23 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF418 ZNF443 ZNF445	1.33e-08	358	105	14	PS50805
Domain	hnRNP_C	HNRNPCL1 HNRNPC HNRNPCL4 HNRNPCL2	1.40e-08	6	105	4	IPR017347
Domain	KRAB	ZNF486 ZNF195 ZFP37 ZNF404 ZNF23 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF418 ZNF443 ZNF445	1.95e-08	369	105	14	SM00349
Domain	KRAB	ZNF486 ZNF195 ZFP37 ZNF404 ZNF23 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF418 ZNF443 ZNF445	2.02e-08	370	105	14	IPR001909
Domain	KRAB	ZNF486 ZNF195 ZFP37 ZNF404 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF418 ZNF443 ZNF445	1.08e-07	358	105	13	PF01352
Domain	Haemoglobin_b	HBB HBD	3.10e-04	5	105	2	IPR002337
Domain	S_TKc	RPS6KA4 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 STK25	9.52e-04	359	105	8	SM00220
Domain	PROTEIN_KINASE_ST	RPS6KA4 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 STK25	1.00e-03	362	105	8	PS00108
Domain	MCM	MCM8 MCMDC2	1.10e-03	9	105	2	SM00350
Domain	MCM_dom	MCM8 MCMDC2	1.10e-03	9	105	2	IPR001208
Domain	MCM	MCM8 MCMDC2	1.10e-03	9	105	2	IPR031327
Domain	MCM	MCM8 MCMDC2	1.10e-03	9	105	2	PF00493
Domain	Protein_kinase_ATP_BS	RPS6KA4 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 STK25	1.35e-03	379	105	8	IPR017441
Domain	Pkinase	RPS6KA4 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 STK25	1.39e-03	381	105	8	PF00069
Domain	Globin	HBB HBD	1.99e-03	12	105	2	IPR000971
Domain	Globin	HBB HBD	1.99e-03	12	105	2	PF00042
Domain	GLOBIN	HBB HBD	1.99e-03	12	105	2	PS01033
Domain	ZINC_PROTEASE	ADAMTS2 ADAMTS6 LNPEP TLL2	2.27e-03	98	105	4	PS00142
Domain	-	HBB HBD	2.35e-03	13	105	2	1.10.490.10
Domain	Globin/Proto	HBB HBD	2.35e-03	13	105	2	IPR012292
Domain	Kinase-like_dom	RPS6KA4 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 PRKDC STK25	3.48e-03	542	105	9	IPR011009
Domain	Globin-like	HBB HBD	3.57e-03	16	105	2	IPR009050
Domain	Ser/Thr_kinase_AS	RPS6KA4 CDKL3 DYRK4 CIT CLK1 EIF2AK4 STK25	4.04e-03	357	105	7	IPR008271
Domain	PROTEIN_KINASE_ATP	RPS6KA4 CDKL3 DYRK4 CIT TTBK2 CLK1 EIF2AK4 STK25	4.37e-03	459	105	8	PS00107
Domain	PLAC	ADAMTS2 ADAMTS6	5.03e-03	19	105	2	PS50900
Domain	PLAC	ADAMTS2 ADAMTS6	5.03e-03	19	105	2	IPR010909
Domain	TSP_1	ADAMTS2 ADAMTS6 C8A	5.37e-03	63	105	3	PF00090
Domain	TSP1	ADAMTS2 ADAMTS6 C8A	5.86e-03	65	105	3	SM00209
Domain	TSP1_rpt	ADAMTS2 ADAMTS6 C8A	5.86e-03	65	105	3	IPR000884
Domain	TSP1	ADAMTS2 ADAMTS6 C8A	5.86e-03	65	105	3	PS50092
Domain	Zinc_finger_PHD-type_CS	MTF2 NSD1 CHD5	5.86e-03	65	105	3	IPR019786
Pathway	REACTOME_RHOBTB2_GTPASE_CYCLE	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.06e-05	25	79	4	MM15606
Pathway	REACTOME_RHOBTB1_GTPASE_CYCLE	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.06e-05	25	79	4	MM15608
Pathway	REACTOME_HEME_SIGNALING	CLEC1B HBB HBD	4.65e-05	13	79	3	MM15685
Pathway	REACTOME_RHOBTB_GTPASE_CYCLE	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	5.24e-05	37	79	4	MM15683
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	3.08e-04	58	79	4	MM15149
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	SP1 USP9X ESR2 ZNF195 ZFP37 ZNF23 CYCS ZNF727 ZNF799 ZNF221 ZNF107 ZNF418 ZNF445	3.15e-04	768	79	13	MM14851
Pubmed	The splicing factor hnRNP C regulates expression of co-stimulatory molecules CD80 and CD40 in dendritic cells.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.13e-11	4	109	4	23831410
Pubmed	hnRNPC induces isoform shifts in miR-21-5p leading to cancer development.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.13e-11	4	109	4	35729324
Pubmed	N6-methylation of RNA-bound adenosine regulator HNRNPC promotes vascular endothelial dysfunction in type 2 diabetes mellitus by activating the PSEN1-mediated Notch pathway.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.13e-11	4	109	4	36681355
Pubmed	hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	9.13e-11	4	109	4	10805751
Pubmed	Interaction between nucleosome assembly protein 1-like family members.	HNRNPCL1 MTF2 HNRNPC HNRNPCL3 HNRNPCL2	2.14e-10	12	109	5	21333655
Pubmed	Heterogeneous nuclear ribonucleoprotein C1 may control miR-30d levels in endometrial exosomes affecting early embryo implantation.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	4.55e-10	5	109	4	29846695
Pubmed	Characterization of two nuclear proteins that interact with cytochrome P-450 1A2 mRNA. Regulation of RNA binding and possible role in the expression of the Cyp1a2 gene.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	4.55e-10	5	109	4	9128719
Pubmed	Evaluating the role of hnRNP-C and FMRP in the cAMP-induced APP metabolism.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	4.55e-10	5	109	4	25809670
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	HNRNPCL1 RPS6KA4 RPS2 LARP1 PFN1 HNRNPC DDX1 HNRNPCL3 JPH1 TSR1 CHD5 HNRNPCL4 HADHA PRKDC HBB HBD RPL7 HNRNPCL2	9.71e-10	949	109	18	36574265
Pubmed	Opposite Dysregulation of Fragile-X Mental Retardation Protein and Heteronuclear Ribonucleoprotein C Protein Associates with Enhanced APP Translation in Alzheimer Disease.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.36e-09	6	109	4	26048669
Pubmed	Selective disruption of genes expressed in totipotent embryonal stem cells.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.36e-09	6	109	4	1317320
Pubmed	Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.36e-09	6	109	4	15687492
Pubmed	Concomitant transitory up-regulation of X-linked inhibitor of apoptosis protein (XIAP) and the heterogeneous nuclear ribonucleoprotein C1-C2 in surviving cells during neuronal apoptosis.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.36e-09	6	109	4	18363099
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	3.17e-09	7	109	4	25846207
Pubmed	Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.14e-08	9	109	4	10452948
Pubmed	Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.	HNRNPCL1 NRDC USP9X CIT HNRNPC HNRNPCL3 CD63 HADHA HNRNPCL2	4.28e-08	226	109	9	37839992
Pubmed	The biogenesis of the coiled body during early mouse development.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	4.43e-08	12	109	4	7768196
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HNRNPCL1 ZNF48 NSD1 LARP1 HNRNPC DDX1 HNRNPCL3 BRCA2 ZSCAN21 CYCS CD63 PRKDC HBB HBD NIPBL HNRNPCL2	4.99e-08	954	109	16	36373674
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	HNRNPCL1 RPS2 USP9X LARP1 USP9Y PFN1 HNRNPC DDX1 GLB1 TSR1 CHD5 HADHA PRKDC SCFD1 KRT37 RPL7 SPATA13	1.16e-07	1153	109	17	29845934
Pubmed	A method to identify cDNAs based on localization of green fluorescent protein fusion products.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	2.11e-07	17	109	4	10716735
Pubmed	Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.	HNRNPCL1 GRIA2 HNRNPC HNRNPCL3 HNRNPCL2	4.71e-07	49	109	5	27352031
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HNRNPCL1 NRDC RPS2 INPP4A USP9X LARP1 GRIA2 PFN1 CIT HNRNPC DDX1 HNRNPCL3 CYCS HADHA HBB HBD RPL7 HNRNPCL2	4.90e-07	1431	109	18	37142655
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SCN11A HNRNPCL1 LARP1 GRIA2 HNRNPC DDX1 FER1L6 HNRNPCL3 STARD9 H4C7 CHD5 CYCS EIF2AK4 HADHA PRKDC NIPBL HNRNPCL2 SPATA13	5.47e-07	1442	109	18	35575683
Pubmed	Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.	RPS2 HNRNPC DDX1 EIF2AK4 HADHA PRKDC HSD17B11 RPL7	1.08e-06	244	109	8	28902428
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	HNRNPCL1 RPS2 HNRNPC DDX1 TSR1 RPL7	1.29e-06	109	109	6	29511296
Pubmed	Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.29e-06	26	109	4	15890332
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF486 ZNF195 ZNF253 ZNF264 ZNF799 ZNF107 ZNF445	1.75e-06	181	109	7	37372979
Pubmed	The protein interaction landscape of the human CMGC kinase group.	HNRNPCL1 RPS6KA4 USP9X LAMA1 CDKL3 LARP1 DYRK4 PFN1 HNRNPC CLK1 AKAP11 ZNF30	1.98e-06	695	109	12	23602568
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	LARP1 PFN1 HNRNPC DDX1 HADHA PRKDC RPL7	2.42e-06	190	109	7	15161933
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	RPS2 LARP1 USP9Y REPIN1 HNRNPC DDX1 PGM3 TSR1 HADHA PRKDC HSD17B11 RPL7	3.05e-06	725	109	12	27025967
Pubmed	Estrogen receptor (ER) beta or p53 attenuates ERalpha-mediated transcriptional activation on the BRCA2 promoter.	SP1 ESR2 BRCA2	3.54e-06	10	109	3	18765668
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	RPS2 PFN1 HNRNPC DDX1 CYCS HADHA PRKDC HBB RPL7	4.69e-06	397	109	9	21319273
Pubmed	Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.	HNRNPCL1 LARP1 CDK5RAP2 AKAP11 PRKDC	6.21e-06	82	109	5	30274258
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	HNRNPCL1 MCM8 NRDC LARP1 DDX1 HNRNPCL3 GLB1 TSR1 HNRNPCL4 EIF2AK4 HSD17B11	6.54e-06	650	109	11	38777146
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NRDC NSD1 REPIN1 ZFP37 TTBK2 ZSCAN21 TSR1 ATRNL1 CDK5RAP2 EIF2AK4 TYW1 TSTD2 STK25 ZNF445	7.69e-06	1084	109	14	11544199
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GBF1 NRDC RPS2 USP9X LARP1 PFN1 HNRNPC DDX1 TSR1 STARD9 CYCS HADHA PRKDC SCFD1 NIPBL RPL7	9.53e-06	1425	109	16	30948266
Pubmed	Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.	HBB HBD	9.73e-06	2	109	2	37902616
Pubmed	Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.	HBB HBD	9.73e-06	2	109	2	270684
Pubmed	Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.	HBB HBD	9.73e-06	2	109	2	21099112
Pubmed	A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus.	HBB HBD	9.73e-06	2	109	2	11121056
Pubmed	Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat.	SP1 PRKDC	9.73e-06	2	109	2	9525578
Pubmed	Decreased hepcidin mRNA expression in thalassemic mice.	HBB HBD	9.73e-06	2	109	2	14675418
Pubmed	Nucleotide sequences of the mouse globin beta gene cDNAs in a wild derived new haplotype Hbb(w1).	HBB HBD	9.73e-06	2	109	2	10441738
Pubmed	Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche.	HBB HBD	9.73e-06	2	109	2	32344432
Pubmed	Responses of primary osteoblasts and osteoclasts from hemizygous β-globin knockout thalassemic mice with elevated plasma glucose to 1,25-dihydroxyvitamin D3.	HBB HBD	9.73e-06	2	109	2	31562377
Pubmed	Effects of human gamma-globin in murine beta-thalassaemia.	HBB HBD	9.73e-06	2	109	2	16803575
Pubmed	The adult beta-globin genes of the "single" type mouse C57BL.	HBB HBD	9.73e-06	2	109	2	7237554
Pubmed	Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.	USP9X USP9Y	9.73e-06	2	109	2	12895410
Pubmed	Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in β-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption.	HBB HBD	9.73e-06	2	109	2	27245334
Pubmed	Co-inheritance of alpha- and beta-thalassaemia in mice ameliorates thalassaemic phenotype.	HBB HBD	9.73e-06	2	109	2	17493845
Pubmed	An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression.	HBB HBD	9.73e-06	2	109	2	28641125
Pubmed	A mouse model for beta 0-thalassemia.	HBB HBD	9.73e-06	2	109	2	8524813
Pubmed	Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.	HBB HBD	9.73e-06	2	109	2	25616571
Pubmed	The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1).	LARP1 EIF2AK4	9.73e-06	2	109	2	35863436
Pubmed	Neutralizing the function of a β-globin-associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain.	HBB HBD	9.73e-06	2	109	2	23074246
Pubmed	High phosphate intake induces bone loss in nephrectomized thalassemic mice.	HBB HBD	9.73e-06	2	109	2	35622784
Pubmed	A humanized mouse model for a common beta0-thalassemia mutation.	HBB HBD	9.73e-06	2	109	2	15780748
Pubmed	Evolution of the mouse beta-globin genes: a recent gene conversion in the Hbbs haplotype.	HBB HBD	9.73e-06	2	109	2	3870864
Pubmed	Molecular characterization of (deltabeta)(0)/beta(0)-thalassemia and (deltabeta)(0)-thalassemia/hemoglobin E in Thai patients.	HBB HBD	9.73e-06	2	109	2	11860449
Pubmed	Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb.	HBB HBD	9.73e-06	2	109	2	12127975
Pubmed	The chromatin "landscape" of a murine adult β-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer.	HBB HBD	9.73e-06	2	109	2	24817273
Pubmed	Ligation-mediated amplification of RNA from murine erythroid cells reveals a novel class of beta globin mRNA with an extended 5'-untranslated region.	HBB HBD	9.73e-06	2	109	2	8041612
Pubmed	A 66-base pair insert bridges the deletion responsible for a mouse model of beta-thalassemia.	HBB HBD	9.73e-06	2	109	2	3017971
Pubmed	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.	USP9X USP9Y	9.73e-06	2	109	2	8922996
Pubmed	Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.	HBB HBD	9.73e-06	2	109	2	273235
Pubmed	Mild-intensity physical activity prevents cardiac and osseous iron deposition without affecting bone mechanical property or porosity in thalassemic mice.	HBB HBD	9.73e-06	2	109	2	35396390
Pubmed	Molecular characterization of a novel homozygous deletion in β-globin cluster causing (δβ)0-Thalassemia among Tunisian family.	HBB HBD	9.73e-06	2	109	2	36214153
Pubmed	The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.	HBB HBD	9.73e-06	2	109	2	728996
Pubmed	CNTO 530 increases expression of HbA and HbF in murine models of β-thalassemia and sickle cell anemia.	HBB HBD	9.73e-06	2	109	2	23157711
Pubmed	HbA2-Partinico or delta(A2)Pro-->Thr, a new genetic variation in the delta-globin gene in cis to the beta(+) thal IVS-I-110 G>A, and the heterogeneity of delta-globin alleles in double heterozygotes for beta- and delta-globin gene defects.	HBB HBD	9.73e-06	2	109	2	19609526
Pubmed	Discovery of a new HBB haplotype w2 in a wild-derived house mouse, Mus musculus.	HBB HBD	9.73e-06	2	109	2	18299925
Pubmed	Transposition of a long member of the L1 major interspersed DNA family into the mouse beta globin gene locus.	HBB HBD	9.73e-06	2	109	2	2991851
Pubmed	A negative regulatory sequence near the mouse beta-maj globin gene associated with a region of potential Z-DNA.	HBB HBD	9.73e-06	2	109	2	6086313
Pubmed	Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain.	HBB HBD	9.73e-06	2	109	2	22203977
Pubmed	ERβ-dependent effects on uterine endothelial cells are cell specific and mediated via Sp1.	SP1 ESR2	9.73e-06	2	109	2	23756706
Pubmed	A humanized BAC transgenic/knockout mouse model for HbE/beta-thalassemia.	HBB HBD	9.73e-06	2	109	2	16631345
Pubmed	A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer.	HBB HBD	9.73e-06	2	109	2	12480689
Pubmed	Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence.	HBB HBD	9.73e-06	2	109	2	482942
Pubmed	Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.	HBB HBD	9.73e-06	2	109	2	11830454
Pubmed	Second generation knockout sickle mice: the effect of HbF.	HBB HBD	9.73e-06	2	109	2	11154217
Pubmed	The complete nucleotide sequence of a beta-globin-like structure, beta h2, from the [Hbb]d mouse BALB/c.	HBB HBD	9.73e-06	2	109	2	6736028
Pubmed	Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.	USP9X USP9Y	9.73e-06	2	109	2	12925892
Pubmed	Running exercise alleviates trabecular bone loss and osteopenia in hemizygous β-globin knockout thalassemic mice.	HBB HBD	9.73e-06	2	109	2	24780610
Pubmed	First report on the co-inheritance of beta-globin IVS-I-5 (G-->C) thalassemia with delta globin CD12 {Asn-->Lys (AAT-->AAA)}HbA₂-NYU in Iran.	HBB HBD	9.73e-06	2	109	2	21194254
Pubmed	Significance of borderline hemoglobin A2 values in an Italian population with a high prevalence of beta-thalassemia.	HBB HBD	9.73e-06	2	109	2	18603555
Pubmed	Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns.	HBB HBD	9.73e-06	2	109	2	264241
Pubmed	Lack of neighborhood effects from a transcriptionally active phosphoglycerate kinase-neo cassette located between the murine beta-major and beta-minor globin genes.	HBB HBD	9.73e-06	2	109	2	11418464
Pubmed	Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S.	HBB HBD	9.73e-06	2	109	2	21304105
Pubmed	In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.	HBB HBD	9.73e-06	2	109	2	30422819
Pubmed	β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications.	HBB HBD	9.73e-06	2	109	2	24297746
Pubmed	Cloning and amplification of alpha and beta mouse globin gene sequences synthesised in vitro.	HBB HBD	9.73e-06	2	109	2	338418
Pubmed	Nephrectomy Does not Exacerbate Cancellous Bone loss in Thalassemic Mice.	HBB HBD	9.73e-06	2	109	2	32385316
Pubmed	The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.	HBB HBD	9.73e-06	2	109	2	519759
Pubmed	Humanized beta-thalassemia mouse model containing the common IVSI-110 splicing mutation.	HBB HBD	9.73e-06	2	109	2	16421096
Pubmed	Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.	HBB HBD	9.73e-06	2	109	2	7935410
Pubmed	Successful treatment of murine beta-thalassemia intermedia by transfer of the human beta-globin gene.	HBB HBD	9.73e-06	2	109	2	11877258
Pubmed	Tracking of mouse cell lineage using microinjected DNA sequences: analyses using genomic Southern blotting and tissue-section in situ hybridizations.	HBB HBD	9.73e-06	2	109	2	3428512
Pubmed	The molecular characterization of an A:T to G:C transition in the Hbb-b1 gene of the murine homologue of hemoglobin Rainier.	HBB HBD	9.73e-06	2	109	2	1820025
Pubmed	Super-resolution imaging reveals three-dimensional folding dynamics of the β-globin locus upon gene activation.	HBB HBD	9.73e-06	2	109	2	22767512
Pubmed	Transgene copy number-dependent rescue of murine beta-globin knockout mice carrying a 183 kb human beta-globin BAC genomic fragment.	HBB HBD	9.73e-06	2	109	2	15820143
Interaction	HNRNPCL3 interactions	HNRNPCL1 CIT HNRNPC HNRNPCL3 HNRNPCL2	1.04e-07	23	104	5	int:HNRNPCL3
Interaction	TRIM28 interactions	ZNF486 RPS2 HTATIP2 ZNF195 LARP1 GRIA2 CIT HNRNPC PGM3 GLB1 BRCA2 ZNF253 CYCS ZNF264 ZNF799 HADHA PRKDC SCFD1 ZNF30 ZNF107 ZNF418 NIPBL ZNF443 ZNF445	3.54e-07	1474	104	24	int:TRIM28
Interaction	CLK3 interactions	HNRNPCL1 NRDC USP9X ESR2 LARP1 USP9Y HNRNPC CLK1 HNRNPCL2	2.09e-06	220	104	9	int:CLK3
Interaction	CUL9 interactions	SEMA4D HNRNPC JPH1 CLK1 CYCS HADHA ZNF107 ZNF445	2.94e-06	171	104	8	int:CUL9
Interaction	TNIP1 interactions	HNRNPCL1 RPS6KA4 RPS2 LARP1 PFN1 HNRNPC DDX1 HNRNPCL3 JPH1 GLB1 TSR1 CHD5 HNRNPCL4 HADHA PRKDC SCFD1 HBB HBD RPL7 HNRNPCL2	3.51e-06	1217	104	20	int:TNIP1
Interaction	CLK2 interactions	HNRNPCL1 LARP1 REPIN1 HNRNPC BRCA2 ZSCAN21 CLK1 ZNF30	7.75e-06	195	104	8	int:CLK2
Interaction	TMPO interactions	RPS2 ESR2 CIT HNRNPC DDX1 JPH1 CLK1 CDK5RAP2 EIF2AK4 TYW1 HADHA PRKDC SCFD1 HSD17B11 RPL7	8.39e-06	762	104	15	int:TMPO
Interaction	DNAJC1 interactions	ESR2 JPH1 TSR1 LNPEP AKAP11 TYW1 HADHA SCFD1 HSD17B11 RPL7	1.76e-05	361	104	10	int:DNAJC1
Interaction	RALYL interactions	HNRNPCL1 CIT HNRNPC HNRNPCL3 HNRNPCL2	2.31e-05	66	104	5	int:RALYL
Interaction	KIF20A interactions	VWA8 RPS2 ESR2 LARP1 USP9Y CIT HNRNPC DDX1 HNRNPCL3 GLB1 H4C7 CDK5RAP2 HADHA PRKDC RPL7 HNRNPCL2 STK25	2.61e-05	1052	104	17	int:KIF20A
Interaction	LMNA interactions	RPS2 NSD1 ZNF195 RETSAT CIT ABCA9 HNRNPC BRCA2 ZSCAN21 TSR1 CLK1 H4C7 CDK5RAP2 PRKDC SCFD1 HSD17B11 COA7 NIPBL KRT37	2.85e-05	1286	104	19	int:LMNA
Interaction	FASN interactions	SP1 HNRNPCL1 GBF1 MCM8 MTF2 INPP4A USP9X ESR2 PFN1 CIT REPIN1 HNRNPC PGM3 HNRNPCL3 HSD17B11 NIPBL HNRNPCL2	2.94e-05	1062	104	17	int:FASN
Interaction	REV1 interactions	ESR2 BRCA2 CLK1 REV1	3.10e-05	35	104	4	int:REV1
Interaction	DYRK2 interactions	RPS2 LARP1 DYRK4 DDX1 TSR1 PRKDC RPL7	3.21e-05	173	104	7	int:DYRK2
Interaction	KCNS3 interactions	RETSAT JPH1 ANKRD13C TYW1	3.88e-05	37	104	4	int:KCNS3
Interaction	CIT interactions	VWA8 RPS2 HCN1 ESR2 LARP1 CIT HNRNPC DDX1 HNRNPCL3 TSR1 H4C7 CDK5RAP2 HNRNPCL4 PRR14L HADHA PRKDC ZNF107 NIPBL RPL7 HNRNPCL2	4.52e-05	1450	104	20	int:CIT
Interaction	SMC5 interactions	HNRNPCL1 ZNF48 NSD1 LARP1 HNRNPC DDX1 HNRNPCL3 BRCA2 ZSCAN21 CYCS CD63 PRKDC HBB HBD NIPBL HNRNPCL2	5.21e-05	1000	104	16	int:SMC5
Interaction	NEFM interactions	VWA8 CIT ABCC12 HADHA HBB KRT37 RPL7	5.83e-05	190	104	7	int:NEFM
Interaction	ANXA2 interactions	SP1 HNRNPCL1 RPS2 PFN1 CIT ABCA9 HNRNPC PRKDC NIPBL HNRNPCL2	6.21e-05	419	104	10	int:ANXA2
Interaction	NOTCH2 interactions	SP1 ZNF48 RPS2 ESR2 REPIN1 ZSCAN21 ZNF253 HSD17B11 ZNF107 ZNF445	6.72e-05	423	104	10	int:NOTCH2
Interaction	GPHN interactions	NRDC USP9X HCN1 PFN1 HNRNPC HADHA	6.87e-05	134	104	6	int:GPHN
Interaction	DCLRE1C interactions	USP9Y BRCA2 AKAP11 PRKDC	7.07e-05	43	104	4	int:DCLRE1C
Interaction	RAD21L1 interactions	CIT CLK1	7.89e-05	3	104	2	int:RAD21L1
Interaction	CHMP4B interactions	RPS2 USP9X CIT HNRNPC GLB1 BRCA2 H4C7 CDK5RAP2 AKAP11 HADHA PRKDC RPL7 HNRNPCL2	9.38e-05	727	104	13	int:CHMP4B
Interaction	PTCD1 interactions	HNRNPCL1 VWA8 RPS2 ESR2 CIT HNRNPC	9.48e-05	142	104	6	int:PTCD1
Interaction	VRK1 interactions	RPS2 CIT HNRNPC H4C7 HADHA PRKDC RPL7 HNRNPCL2	9.49e-05	277	104	8	int:VRK1
Interaction	RPS27L interactions	GBF1 RPS2 ESR2 CIT REPIN1 TSR1 RPL7	9.68e-05	206	104	7	int:RPS27L
Interaction	PPHLN1 interactions	HNRNPCL1 ESR2 HNRNPC RGMA CLK1 HNRNPCL2	1.10e-04	146	104	6	int:PPHLN1
Interaction	MGMT interactions	SP1 ESR2 HNRNPC BRCA2 PRKDC	1.14e-04	92	104	5	int:MGMT
Interaction	PRC1 interactions	GBF1 RPS2 ESR2 LARP1 CIT HNRNPC DDX1 GLB1 H4C7 CHD5 CDK5RAP2 HADHA PRKDC RPL7 HNRNPCL2	1.38e-04	973	104	15	int:PRC1
Interaction	MATR3 interactions	HNRNPCL1 RPS2 USP9X LARP1 USP9Y CIT HNRNPC DDX1 TSR1 EIF2AK4 PRKDC RPL7	1.42e-04	655	104	12	int:MATR3
Interaction	MCMDC2 interactions	ESR2 MCMDC2	1.57e-04	4	104	2	int:MCMDC2
Interaction	ZFP62 interactions	ZNF48 ESR2 ZFP37 ZSCAN21 RPL7	1.62e-04	99	104	5	int:ZFP62
Interaction	ZYG11A interactions	BRCA2 ZNF264 ZNF418	1.66e-04	21	104	3	int:ZYG11A
Interaction	NBAS interactions	ESR2 PFN1 CIT SCFD1 HSD17B11	1.86e-04	102	104	5	int:NBAS
Interaction	PRPF38A interactions	HNRNPCL1 ESR2 CIT CLK1 CYCS HNRNPCL2	1.88e-04	161	104	6	int:PRPF38A
Interaction	PHB1 interactions	VWA8 RPS2 ESR2 LARP1 USP9Y CIT REPIN1 HNRNPC DDX1 PGM3 TSR1 CYCS HADHA PRKDC HSD17B11 RPL7	2.01e-04	1123	104	16	int:PHB1
Interaction	BRCA1 interactions	SP1 GBF1 RPS6KA4 RPS2 USP9X ESR2 LARP1 PFN1 CIT HNRNPC DDX1 BRCA2 ZSCAN21 PRKDC NIPBL RPL7 REV1	2.14e-04	1249	104	17	int:BRCA1
Interaction	NCL interactions	SP1 ZNF48 RPS2 ESR2 PFN1 CIT JPH1 BRCA2 TSR1 CLK1 ABCC12 EIF2AK4 RPL7	2.35e-04	798	104	13	int:NCL
Interaction	GTF3C2 interactions	RPS2 ESR2 GRIA2 CIT GTF3A HNRNPCL2	2.45e-04	169	104	6	int:GTF3C2
Interaction	PPP1CA interactions	ESR2 LARP1 PFN1 CIT HNRNPC DDX1 AKAP11 EIF2AK4 HADHA PRKDC COA7 RPL7	2.48e-04	696	104	12	int:PPP1CA
Interaction	HEXIM1 interactions	HNRNPCL1 RPS2 USP9X ESR2 USP9Y PFN1 HNRNPC DDX1 CHD5 HADHA PRKDC SCFD1 KRT37 RPL7	2.48e-04	913	104	14	int:HEXIM1
Interaction	ORC2 interactions	MCM8 ESR2 CIT HBB HNRNPCL2	2.65e-04	110	104	5	int:ORC2
Interaction	RFC2 interactions	ESR2 CIT DDX1 BRCA2 PRKDC HNRNPCL2	2.87e-04	174	104	6	int:RFC2
Interaction	ZNF746 interactions	RPS2 USP9X ESR2 ZFP37 PGM3 HADHA PRKDC RPL7	2.88e-04	326	104	8	int:ZNF746
Interaction	HDAC6 interactions	GBF1 RPS2 USP9X ESR2 HTATIP2 LARP1 PFN1 DDX1 BRCA2 CYCS HADHA PRKDC HBD RPL7	2.96e-04	929	104	14	int:HDAC6
Interaction	CTCFL interactions	SP1 ZNF48 ZFP37 ZSCAN21	2.97e-04	62	104	4	int:CTCFL
Interaction	KPNA3 interactions	HNRNPCL1 NRDC USP9X ESR2 CIT HNRNPC HADHA	3.03e-04	248	104	7	int:KPNA3
Interaction	CRNKL1 interactions	HNRNPCL1 USP9X CIT HNRNPC CLK1 HNRNPCL2	3.14e-04	177	104	6	int:CRNKL1
Interaction	IDE interactions	NRDC ESR2 CDKL3 DDX1 GLB1 C8A	3.44e-04	180	104	6	int:IDE
Interaction	EVA1C interactions	GBF1 RETSAT TYW1 STK25	3.56e-04	65	104	4	int:EVA1C
Interaction	RPS29 interactions	RPS2 ESR2 LARP1 CIT TSR1 RPL7	3.64e-04	182	104	6	int:RPS29
Interaction	STK38 interactions	GBF1 MTF2 RETSAT PRKDC NIPBL HNRNPCL2	3.64e-04	182	104	6	int:STK38
Interaction	CFAP251 interactions	ESR2 CLK1	3.90e-04	6	104	2	int:CFAP251
Interaction	FSBP interactions	HNRNPC HNRNPCL2	3.90e-04	6	104	2	int:FSBP
Interaction	HNRNPCL4 interactions	CIT HNRNPCL4	3.90e-04	6	104	2	int:HNRNPCL4
Interaction	MROH2B interactions	GBF1 CIT	3.90e-04	6	104	2	int:MROH2B
Interaction	NIFK interactions	ZNF48 RPS2 USP9X ESR2 NSD1 LARP1 CIT ZSCAN21 RPL7	3.94e-04	431	104	9	int:NIFK
Interaction	RABL2A interactions	BRCA2 AKAP11 HNRNPCL2	3.98e-04	28	104	3	int:RABL2A
Interaction	PLXNA4 interactions	HNRNPCL1 HNRNPCL3 HNRNPCL2	3.98e-04	28	104	3	int:PLXNA4
Interaction	EED interactions	RPS6KA4 MTF2 RPS2 USP9X ESR2 LAMA1 NSD1 PFN1 CIT HNRNPC DDX1 HADHA PRKDC SCFD1 HSD17B11 NIPBL RPL7 HNRNPCL2	4.03e-04	1445	104	18	int:EED
Interaction	XAB2 interactions	HNRNPCL1 ESR2 CIT HNRNPC BRCA2 HNRNPCL2	4.09e-04	186	104	6	int:XAB2
Interaction	NPM1 interactions	SP1 RPS2 ESR2 NSD1 LARP1 GRIA2 PFN1 CIT HNRNPC DDX1 BRCA2 TSR1 CLK1 AKAP11 PRKDC RPL7	4.25e-04	1201	104	16	int:NPM1
Cytoband	15q15.2	GANC TTBK2 STARD9	7.13e-06	16	109	3	15q15.2
Cytoband	Ensembl 112 genes in cytogenetic band chr15q15	GANC TTBK2 STARD9 EIF2AK4	4.32e-04	147	109	4	chr15q15
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP1 ZNF486 ZNF48 FEZF2 ZNF195 REPIN1 ZFP37 ZNF404 ZNF23 GTF3A ZSCAN21 ZNF253 ZNF727 ZNF264 ZNF799 ZNF221 ZNF30 ZNF107 ZNF418 ZNF443 ZNF445	5.91e-13	718	74	21	28
GeneFamily	MCM family	MCM8 MCMDC2	5.84e-04	9	74	2	1085
GeneFamily	Hemoglobin subunits	HBB HBD	7.28e-04	10	74	2	940
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS2 ADAMTS6	2.70e-03	19	74	2	50
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_DN	HNRNPCL1 HNRNPC HNRNPCL3 HNRNPCL2	1.51e-05	37	106	4	MM570
Coexpression	LEE_DIFFERENTIATING_T_LYMPHOCYTE	SP1 SEMA4D MTF2 INPP4A GTF3A LNPEP SPATA13	1.80e-05	201	106	7	M2200
Drug	vinylene	SP1 FEZF2 RPS2 NSD1 LGSN ZSCAN21 ZNF264 ZNF107 ZNF418 ZNF445	2.23e-07	245	106	10	CID000006326
Drug	nifedipine; Up 200; 10uM; MCF7; HG-U133A	SP1 GBF1 ADAMTS2 RPS2 HTATIP2 CDKL3 TSR1 ZNF264 NIPBL	3.93e-07	199	106	9	603_UP
Drug	1,2,4-tribromobenzene	CYCS HBB HBD	9.74e-07	5	106	3	CID000012002
Drug	tricapryl(methyl)ammonium	HBB HBD	2.15e-05	2	106	2	CID011071504
Drug	allyl 2,4,6-tribromophenyl ether	HBB HBD	2.15e-05	2	106	2	CID000076767
Drug	1,3,5-tribromobenzene	HBB HBD	2.15e-05	2	106	2	CID000012279
Drug	K 81	CIT GLB1	2.15e-05	2	106	2	CID005744870
Drug	2-(alpha-hydroxybenzyl)-benzimidazole	HBB HBD	2.15e-05	2	106	2	CID000005792
Drug	NSC-334295	HBB HBD	2.15e-05	2	106	2	CID000100107
Drug	AC1L3OJQ	HBB HBD	2.15e-05	2	106	2	CID000119294
Drug	pentabromobenzene	HBB HBD	2.15e-05	2	106	2	CID000011854
Drug	tribromobenzene	HBB HBD	2.15e-05	2	106	2	CID000011842
Drug	Bromkal 73-5 PE	HBB HBD	2.15e-05	2	106	2	CID000118216
Drug	hydroxyethylretinamide	ESR2 GLB1 BRCA2 HBB HBD	2.32e-05	73	106	5	CID006437840
Drug	ketononestrol aziridine	ESR2 HBB HBD	2.71e-05	13	106	3	CID000130642
Drug	ara-Hx	GANC MTF2 GRIA2 CIT HBB HBD STK25	3.39e-05	193	106	7	CID000000804
Drug	AD 288	RPS6KA4 CYCS PRKDC	3.44e-05	14	106	3	CID000073553
Drug	clofibrate; Down 200; 150uM; MCF7; HG-U133A	INPP4A ESR2 DYRK4 PGM3 BRCA2 CDK5RAP2 ZNF107	3.86e-05	197	106	7	263_DN
Drug	Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; HL60; HG-U133A	VWA8 MTF2 RPS2 DYRK4 REPIN1 PRKDC NIPBL	3.86e-05	197	106	7	1386_DN
Drug	diacetyldeuteroheme	CYCS HBB HBD	4.28e-05	15	106	3	CID004629150
Drug	mizolastine	CD63 HBB HBD	5.26e-05	16	106	3	CID000065906
Drug	HBED	CIT HBB HBD	5.26e-05	16	106	3	CID000037336
Drug	furyl-dihydropyridine I	HBB HBD	6.42e-05	3	106	2	CID000125806
Drug	pentabromoethylbenzene	HBB HBD	6.42e-05	3	106	2	CID000006800
Drug	Nx-D	HBB HBD	6.42e-05	3	106	2	CID006914638
Drug	mer13	HBB HBD	6.42e-05	3	106	2	CID000107453
Drug	BTBPE	HBB HBD	6.42e-05	3	106	2	CID000037840
Drug	DNTB	HNRNPCL1 HTATIP2 CR2 HNRNPC CLK1 HBB HBD	6.91e-05	216	106	7	CID000015325
Drug	AC1L18ZJ	HADHA HBB HBD	7.61e-05	18	106	3	CID000000324
Drug	Camptothecin	SP1 ESR2 HNRNPC BRCA2 CYCS PRKDC	1.16e-04	163	106	6	ctd:D002166
Drug	1q65	MTF2 LGSN HBB HBD	1.17e-04	54	106	4	CID000448017
Drug	HPED	HBB HBD	1.28e-04	4	106	2	CID000125856
Drug	4-(2-carboxyvinyl)benzoic acid	HBB HBD	1.28e-04	4	106	2	CID000089196
Drug	1,4-dibromobenzene	HBB HBD	1.28e-04	4	106	2	CID000007804
Drug	3,3'-diClBPA	ESR2 CYCS	1.28e-04	4	106	2	CID000066238
Drug	AC1L4CDO	HBB HBD	1.28e-04	4	106	2	CID000154482
Drug	PTU-23	HBB HBD	1.28e-04	4	106	2	CID000853760
Drug	AC1L9JVG	HBB HBD	1.28e-04	4	106	2	CID000446603
Drug	griseoluteic acid	LGSN CYCS	1.28e-04	4	106	2	CID000120266
Drug	1,2,4,5-tetrabromobenzene	HBB HBD	1.28e-04	4	106	2	CID000012486
Drug	potassium ferricyanide	FEZF2 CYCS HBB HBD	1.35e-04	56	106	4	CID000026250
Drug	N,N-dimethylacrylamide	FEZF2 HBB HBD	1.42e-04	22	106	3	CID000017587
Drug	tamoxifen aziridine	ESR2 HBB HBD	1.42e-04	22	106	3	CID003033894
Disease	Delta-Beta Thalassemia	HBB HBD	3.47e-05	3	101	2	C0271985
Disease	beta thalassemia (implicated_via_orthology)	HBB HBD	3.47e-05	3	101	2	DOID:12241 (implicated_via_orthology)
Disease	hemoglobin measurement, hemoglobin A2 measurement	HBD HBD	1.15e-04	5	101	2	EFO_0004509, EFO_0005845
Disease	hemoglobin E disease	HBD HBD	1.72e-04	6	101	2	MONDO_0016243
Disease	Chloracne	CYCS HBB HBD	1.97e-04	33	101	3	C0263454
Disease	anemia (biomarker_via_orthology)	HBB HBD	2.41e-04	7	101	2	DOID:2355 (biomarker_via_orthology)
Disease	neurexophilin-1 measurement	HNRNPC C8A	3.20e-04	8	101	2	EFO_0008244
Disease	microcephaly (is_implicated_in)	NSD1 CDK5RAP2	3.20e-04	8	101	2	DOID:10907 (is_implicated_in)
Disease	unipolar depression, response to bupropion, mood disorder	HCN1 ADAMTS6	1.91e-03	19	101	2	EFO_0003761, EFO_0004247, EFO_0006326
Disease	anti-Mullerian hormone measurement	MCM8 RGMA	2.12e-03	20	101	2	EFO_0004769
Disease	Primary microcephaly	CIT CDK5RAP2	2.56e-03	22	101	2	C0431350
Disease	Autosomal Recessive Primary Microcephaly	CIT CDK5RAP2	2.56e-03	22	101	2	C3711387
Disease	anxiety disorder (implicated_via_orthology)	HCN1 ESR2	2.56e-03	22	101	2	DOID:2030 (implicated_via_orthology)
Disease	breast cancer (implicated_via_orthology)	ESR2 BRCA2	3.31e-03	25	101	2	DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LFNDGSKGKLNHLCG	PGM3	236	O95394
SKGKLNHLCGADFVK	PGM3	241	O95394
KGGNLAASAKKKHGS	CHD5	1226	Q8TDI0
GDHCKKFGGGKTERA	C8A	396	P07357
HKGKCIGSDEQLGKL	EIF2AK4	281	Q9P2K8
CIGSIQHLKSKFGKD	ABCA9	1501	Q8IUA7
KQEGGDGHCEGKNLK	CDKL3	571	Q8IVW4
SRIGKGGKACHKIFS	ANKRD13C	41	Q8N6S4
GKSSQRKGHKHGKSC	AKAP11	381	Q9UKA4
VDTGHCRGGQFKIKK	ANGPTL1	16	O95841
TAAKCKGLGAKVHTF	HSD17B11	76	Q8NBQ5
IFEAVKGCHLFGAGK	CIT	1681	O14578
KISSKGHCQGDKSIF	ADAMTS2	1056	O95450
IGNSCGTKGHEAAKL	ADAMTS6	416	Q9UKP5
KGGCKNGYLRHTESK	CDK5RAP2	741	Q96SN8
AFGKVVECIDHKAGG	CLK1	171	P49759
GHKAKKPACKFEEGQ	MTF2	36	Q9Y483
KGDLGLSKKCYEAGH	NSD1	1426	Q96L73
HCQGFKSGGLRKKLH	INPP4A	366	Q96PE3
GCGINFNEKAIHKEG	CD63	176	P08962
QARLCAGKKGHGAEL	FGFBP3	131	Q8TAT2
EDCQRGGQKKKGNKH	LARP1	236	Q6PKG0
GKIAGCSVHKGFAFV	HNRNPCL1	41	O60812
LGKGGAKCHRKVLSD	H4C7	11	Q99525
GKIVGCSVHKGFAFV	HNRNPC	41	P07910
GICFIGDLASHKKDK	MCMDC2	406	Q4G0Z9
DEQLHCAGKAKRSGG	ESR2	236	Q92731
GKIAGCSVHKGFAFV	HNRNPCL2	41	B2RXH8
AGGCKHFNLLSSKGA	HTATIP2	121	Q9BUP3
KGQKTKSSEDGCKHG	MCM8	366	Q9UJA3
GKIAGCSVHKGFAFV	HNRNPCL3	41	B7ZW38
ICGAYGKNTLNGHEK	KRT37	91	O76014
NFHADAELAGKKKGG	JPH1	196	Q9HDC5
DGAHKTFLKCGALQG	GLB1	221	P16278
GFGGTGKKSHNKQFD	DDX1	166	Q92499
GHVKFSKNGKDLGLA	DDX1	201	Q92499
HCGFKYKLTIVGDGK	GRIA2	456	P42262
TVTLEKCGHNKGYKG	PGPEP1	81	Q9NXJ5
GKGDLKCHITANPFK	GANC	126	Q8TET4
HGGGLLSSKAKRAKC	NIPBL	1361	Q6KC79
FTKEGCHKKNQSIGL	LNPEP	136	Q9UIQ6
GKIAGCSVHKGFAFV	HNRNPCL4	41	P0DMR1
KVFLVRKAGGHDAGK	RPS6KA4	46	O75676
KKKTTHFVEGGDAGN	RPL7	221	P18124
GKGSFGQVAKCLDHK	DYRK4	111	Q9NR20
KEHGNSVCFKVDGGG	HCN1	51	O60741
GEKKLQCRSDSKGHG	CR2	756	P20023
SQCHTVEKGGKHKTG	CYCS	16	P99999
GNSFKVNSCKDHIGK	BRCA2	271	P51587
DLKEGGKKRFGHICS	CERK	471	Q8TCT0
SGLKIQTGKKCDGQF	CENPJ	471	Q9HC77
LHTGKCFCTTKGIKG	ATRNL1	1071	Q5VV63
GLYHGQVLCKKNKFG	HADHA	341	P40939
LNGGCKSQEKRGKSH	GBF1	1426	Q92538
VKAHGKKVLGAFSDG	HBD	61	P02042
VKAHGKKVLGAFSDG	HBB	61	P68871
GLAHVACSGHGMKQK	FAM215A	16	Q9Y5M1
CGKGFHQKGNYKNHK	FEZF2	366	Q8TBJ5
KCHGEKGTRIENKLG	LGSN	396	Q5TDP6
AGCDQIHGAFAKKGV	PRR14L	1501	Q5THK1
AGQMGKHCGKIKTHF	FER1L6	746	Q2WGJ9
DSAGKACGVSVKKGH	RETSAT	326	Q6NUM9
TKASKHGSENKFGKG	SYDE2	631	Q5VT97
HGSENKFGKGKEIIS	SYDE2	636	Q5VT97
QTSEKKFHIGCEKGG	USP9X	1441	Q93008
KFHIGCEKGGANLIK	USP9X	1446	Q93008
HTLAAKGDHCRGGKK	TIGD6	191	Q17RP2
KEGVHGGLINKKCYE	PFN1	116	P07737
THFKGCLGEAFLNGK	LAMA1	2266	P25391
FKHGGTAELKCSQKS	SEMA4D	566	Q92854
RKEGNLGTHKAAKGA	STARD9	991	Q9P2P6
GKKKQHICHIQGCGK	SP1	621	P08047
QGLGIIHAYGKKESC	ABCC12	996	Q96J65
GSKNGGDKHGANSLK	RGMA	246	Q96B86
FGELKEKHKQSGGSV	STK25	366	O00506
VGKEASKALGAKGSC	RITA1	66	Q96K30
AECGKNFGKKTHLVA	REPIN1	406	Q9BWE0
KQSELKGTFKGHKCS	CLEC1B	86	Q9P126
EKPGKKSIAACHNVG	COA7	101	Q96BR5
QKAGHGKSKGYNRCP	SPATA13	586	Q96N96
CGKAFISGSAFVKHG	ZNF30	181	P17039
GKAFGLCSIFTEHKK	ZNF727	151	A8MUV8
KGCKHVDECTGHKGG	ZNF107	46	Q9UII5
CGKGFGDSSARIKHQ	ZNF48	576	Q96MX3
GTHGHMKCSFDGKLK	TSR1	746	Q2NL82
KCGKAFGQSSDLLKH	ZSCAN21	336	Q9Y5A6
HGDKKKEPVNGCNTG	REV1	966	Q9UBZ9
LHGKGHTGEKPFKCQ	ZNF75CP	281	Q92670
QEHCKPSKNGLKGSG	TTBK2	1206	Q6IQ55
GKNCDKFGIVAHELG	TLL2	231	Q9Y6L7
CGEKPDTHKQRGKAF	ZNF799	136	Q96GE5
SGHHLCKVKALNKGD	NRDC	901	O43847
IKGKQGKHILYGCSE	SCFD1	611	Q8WVM8
KGVCKEVFQLKGGIH	TSTD2	371	Q5T7W7
KGHKGQEDAVAPGCK	SNHG28	16	P0DPA3
EKKYHFGCEKGGANL	USP9Y	1446	O00507
FGKEFDKHFGKGGSK	PRKDC	3636	P78527
ECGKAFGKGSSLLKH	ZNF404	331	Q494X3
SECGKVFNKKHLLAG	ZNF264	206	O43296
CKSVGEHKVHKGGYN	ZNF253	116	O75346
HSGLKGNKKDVCGKD	ZNF445	451	P59923
HSGQKSFKCEECGKG	ZNF221	416	Q9UK13
GECGKSFSHKGSLVQ	ZNF418	261	Q8TF45
CGEKPDTHKQRGKAF	ZNF443	136	Q9Y2A4
GDLSSFGVAKGKVHC	SCN11A	1776	Q9UI33
QEGCGKHFASPSKLK	GTF3A	166	Q92664
ECGKAFSVKGKLIQH	ZNF23	396	P17027
QALQKGERKKSCGGH	TYW1	241	Q9NV66
GDYNGHVGLGVKCSK	RPS2	131	P15880
IGGKGCGKTVIAKNF	VWA8	446	A3KMH1
KFEKCGHGNLHFKKG	ZNF486	111	Q96H40
QAKKNGSDCGSLGKK	ZFP37	146	Q9Y6Q3
GSDCGSLGKKNNLHK	ZFP37	151	Q9Y6Q3
HTGKKFQKCGECGKT	ZNF195	266	O14628
KGGEQKGHDKISASF	TRAV30	71	A0A087WSZ9