Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sulfate adenylyltransferase (ATP) activity	PAPSS2 PAPSS1	3.35e-05	2	116	2	GO:0004781
GeneOntologyMolecularFunction	sulfate adenylyltransferase activity	PAPSS2 PAPSS1	3.35e-05	2	116	2	GO:0004779
GeneOntologyMolecularFunction	adenylylsulfate kinase activity	PAPSS2 PAPSS1	3.35e-05	2	116	2	GO:0004020
GeneOntologyMolecularFunction	inhibin binding	ACVR2A ACVR2B	3.31e-04	5	116	2	GO:0034711
GeneOntologyMolecularFunction	dihydropyrimidinase activity	DPYSL3 DPYSL4	4.94e-04	6	116	2	GO:0004157
GeneOntologyMolecularFunction	phosphoprotein binding	DPYSL3 ACP2 DPYSL4 MAPK1 UBASH3B	6.06e-04	117	116	5	GO:0051219
GeneOntologyMolecularFunction	hydroperoxy icosatetraenoate dehydratase activity	CYP1A1 PTGIS	6.89e-04	7	116	2	GO:0106256
GeneOntologyBiologicalProcess	response to amino acid starvation	SZT2 LARP1 DEPDC5 MAPK1 EIF2A	2.49e-05	61	117	5	GO:1990928
GeneOntologyBiologicalProcess	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	PAPSS2 PAPSS1	3.19e-05	2	117	2	GO:0050428
GeneOntologyBiologicalProcess	purine ribonucleoside bisphosphate biosynthetic process	PAPSS2 PAPSS1	3.19e-05	2	117	2	GO:0034036
GeneOntologyCellularComponent	perinuclear region of cytoplasm	ANKRD13B ATN1 NDFIP2 PLEKHG5 TYR MAGI2 FAT1 GBP4 KCNB1 TRAPPC12 SLC34A1 SBF2 DEPDC5 SEC23B SEC23A CDH13	5.83e-05	934	116	16	GO:0048471
GeneOntologyCellularComponent	GATOR1 complex	SZT2 DEPDC5	3.02e-04	5	116	2	GO:1990130
GeneOntologyCellularComponent	Mon1-Ccz1 complex	CCZ1B CCZ1	3.02e-04	5	116	2	GO:0035658
GeneOntologyCellularComponent	activin receptor complex	ACVR2A ACVR2B	4.51e-04	6	116	2	GO:0048179
Domain	Sulfurylase_cat_dom	PAPSS2 PAPSS1	3.89e-05	2	117	2	IPR024951
Domain	ATP-sulfurylase	PAPSS2 PAPSS1	3.89e-05	2	117	2	PF01747
Domain	-	ASF1B ASF1A	3.89e-05	2	117	2	2.60.40.1490
Domain	PUA_2	PAPSS2 PAPSS1	3.89e-05	2	117	2	PF14306
Domain	ASF1_hist_chap	ASF1B ASF1A	3.89e-05	2	117	2	PF04729
Domain	DUF1712	CCZ1B CCZ1	3.89e-05	2	117	2	PF08217
Domain	APS_kinase	PAPSS2 PAPSS1	3.89e-05	2	117	2	IPR002891
Domain	Sulphate_adenylyltransferase	PAPSS2 PAPSS1	3.89e-05	2	117	2	IPR002650
Domain	ATP-Sase_PUA-like_dom	PAPSS2 PAPSS1	3.89e-05	2	117	2	IPR025980
Domain	DUF1712_fun	CCZ1B CCZ1	3.89e-05	2	117	2	IPR013176
Domain	ASF1-like	ASF1B ASF1A	3.89e-05	2	117	2	IPR006818
Domain	FA58C	CNTNAP1 NRP2 CPXM1	2.93e-04	21	117	3	SM00231
Domain	FA58C_3	CNTNAP1 NRP2 CPXM1	2.93e-04	21	117	3	PS50022
Domain	FA58C_1	CNTNAP1 NRP2 CPXM1	2.93e-04	21	117	3	PS01285
Domain	FA58C_2	CNTNAP1 NRP2 CPXM1	2.93e-04	21	117	3	PS01286
Domain	Galactose-bd-like	MYCBP2 CNTNAP1 PTPRU NRP2 CPXM1	3.12e-04	94	117	5	IPR008979
Domain	F5_F8_type_C	CNTNAP1 NRP2 CPXM1	4.41e-04	24	117	3	PF00754
Domain	FA58C	CNTNAP1 NRP2 CPXM1	4.41e-04	24	117	3	IPR000421
Domain	TRYPSIN_HIS	PRSS57 PRSS27 GZMA GZMM CTSG	4.75e-04	103	117	5	IPR018114
Domain	TRYPSIN_SER	PRSS57 PRSS27 GZMA GZMM CTSG	5.42e-04	106	117	5	PS00135
Domain	TRYPSIN_HIS	PRSS57 PRSS27 GZMA GZMM CTSG	5.66e-04	107	117	5	PS00134
Domain	Sec23/24_helical_dom	SEC23B SEC23A	5.74e-04	6	117	2	IPR006900
Domain	Sec23_24_beta_S	SEC23B SEC23A	5.74e-04	6	117	2	IPR012990
Domain	zf-Sec23_Sec24	SEC23B SEC23A	5.74e-04	6	117	2	PF04810
Domain	Sec23_trunk	SEC23B SEC23A	5.74e-04	6	117	2	PF04811
Domain	Sec23_helical	SEC23B SEC23A	5.74e-04	6	117	2	PF04815
Domain	Hydantoinase/dihydroPyrase	DPYSL3 DPYSL4	5.74e-04	6	117	2	IPR011778
Domain	Sec23_BS	SEC23B SEC23A	5.74e-04	6	117	2	PF08033
Domain	Sec23/24_trunk_dom	SEC23B SEC23A	5.74e-04	6	117	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC23B SEC23A	5.74e-04	6	117	2	IPR006895
Domain	Peptidase_S1A	PRSS57 PRSS27 GZMA GZMM CTSG	7.25e-04	113	117	5	IPR001314
Domain	TRYPSIN_DOM	PRSS57 PRSS27 GZMA GZMM CTSG	7.85e-04	115	117	5	PS50240
Domain	Tryp_SPc	PRSS57 PRSS27 GZMA GZMM CTSG	8.49e-04	117	117	5	SM00020
Domain	Trypsin_dom	PRSS57 PRSS27 GZMA GZMM CTSG	9.87e-04	121	117	5	IPR001254
Domain	Trypsin	PRSS57 PRSS27 GZMA GZMM CTSG	9.87e-04	121	117	5	PF00089
Domain	Peptidase_S1_PA	PRSS57 PRSS27 GZMA GZMM CTSG	1.06e-03	123	117	5	IPR009003
Domain	-	DPYSL3 DPYSL4	1.06e-03	8	117	2	2.30.40.10
Domain	-	MYCBP2 CNTNAP1 NRP2 CPXM1	1.14e-03	73	117	4	2.60.120.260
Domain	Amidohydro_1	DPYSL3 DPYSL4	1.69e-03	10	117	2	PF01979
Domain	Metal-dep_hydrolase_composite	DPYSL3 DPYSL4	1.69e-03	10	117	2	IPR011059
Domain	Activin_recp	ACVR2A ACVR2B	1.69e-03	10	117	2	PF01064
Domain	Activin_recp	ACVR2A ACVR2B	1.69e-03	10	117	2	IPR000472
Domain	Amidohydro-rel	DPYSL3 DPYSL4	2.06e-03	11	117	2	IPR006680
Domain	TGFB_receptor	ACVR2A ACVR2B	2.46e-03	12	117	2	IPR000333
Domain	TRYPSIN_SER	PRSS27 GZMA GZMM CTSG	2.47e-03	90	117	4	IPR033116
Domain	Gelsolin	SEC23B SEC23A	3.37e-03	14	117	2	PF00626
Domain	Dynein_heavy_chain_D4_dom	DNAH7 DNAH9	3.37e-03	14	117	2	IPR024317
Domain	Dynein_HC_stalk	DNAH7 DNAH9	3.37e-03	14	117	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH7 DNAH9	3.37e-03	14	117	2	IPR013602
Domain	DHC_N2	DNAH7 DNAH9	3.37e-03	14	117	2	PF08393
Domain	Gelsolin-like_dom	SEC23B SEC23A	3.37e-03	14	117	2	IPR007123
Domain	MT	DNAH7 DNAH9	3.37e-03	14	117	2	PF12777
Domain	AAA_8	DNAH7 DNAH9	3.37e-03	14	117	2	PF12780
Domain	DHC_fam	DNAH7 DNAH9	3.87e-03	15	117	2	IPR026983
Domain	Dynein_heavy	DNAH7 DNAH9	3.87e-03	15	117	2	PF03028
Domain	Dynein_heavy_dom	DNAH7 DNAH9	3.87e-03	15	117	2	IPR004273
Domain	Post-SET_dom	NSD2 SETDB1	4.41e-03	16	117	2	IPR003616
Domain	PostSET	NSD2 SETDB1	4.41e-03	16	117	2	SM00508
Domain	POST_SET	NSD2 SETDB1	4.41e-03	16	117	2	PS50868
Domain	CarboxyPept-like_regulatory	TENM2 CPXM1	4.98e-03	17	117	2	IPR008969
Domain	MAM	PTPRU NRP2	4.98e-03	17	117	2	SM00137
Domain	MAM	PTPRU NRP2	5.58e-03	18	117	2	PF00629
Domain	MAM_dom	PTPRU NRP2	5.58e-03	18	117	2	IPR000998
Domain	Pept_M10A_stromelysin-type	MMP20 MMP17	5.58e-03	18	117	2	IPR016293
Domain	MAM_2	PTPRU NRP2	5.58e-03	18	117	2	PS50060
Domain	PUA-like_domain	PAPSS2 PAPSS1	6.21e-03	19	117	2	IPR015947
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NDST1 MYCBP2 SZT2 NSD2 BCL9 PLEKHG5 CDC42BPB ACTR1A FAT1 C2CD3 ZNRF3 TRAPPC12 PCNX4 SBF2 HELZ2 DIP2C DEPDC5 MMP17	3.25e-08	1105	117	18	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MYCBP2 ASIC1 CNTNAP1 DPYSL4 GRIK3 BCL9 CDC42BPB TENM2 MAGI2 ACTR1A KCNB1 ANAPC1 FBXO41 MAPK1 UBASH3B SEC23A	1.56e-07	963	117	16	28671696
Pubmed	Novel factors in regulation of activin signaling.	ACVR2A ACVR2B MAGI2	7.37e-07	6	117	3	15451561
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK18 DPYSL3 HIVEP1 MYCBP2 BAG3 LARP1 PARD3B DNAH7 C2CD3 AMOT STARD9 TMEM102 DEPDC1B SEC23B	1.27e-06	861	117	14	36931259
Pubmed	A member of a family of sulfate-activating enzymes causes murine brachymorphism.	PAPSS2 PAPSS1	1.12e-05	2	117	2	9671738
Pubmed	Distinct role of histone chaperone Asf1a and Asf1b during fertilization and pre-implantation embryonic development in mice.	ASF1B ASF1A	1.12e-05	2	117	2	34906203
Pubmed	Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.	CFH CFHR3	1.12e-05	2	117	2	20694013
Pubmed	Cloning and functional characterization of mammalian homologues of the COPII component Sec23.	SEC23B SEC23A	1.12e-05	2	117	2	8898360
Pubmed	Mouse pups lacking collapsin response mediator protein 4 manifest impaired olfactory function and hyperactivity in the olfactory bulb.	DPYSL3 DPYSL4	1.12e-05	2	117	2	26118640
Pubmed	Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells.	PAPSS2 PAPSS1	1.12e-05	2	117	2	10657990
Pubmed	Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization.	PAPSS2 PAPSS1	1.12e-05	2	117	2	10679223
Pubmed	Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms.	PAPSS2 PAPSS1	1.12e-05	2	117	2	11931637
Pubmed	Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.	SEC23B SEC23A	1.12e-05	2	117	2	30065114
Pubmed	Regulation of replication fork progression through histone supply and demand.	ASF1B ASF1A	1.12e-05	2	117	2	18096807
Pubmed	Expression of activin receptor II and IIB mRNA isoforms in mouse reproductive organs and oocytes.	ACVR2A ACVR2B	1.12e-05	2	117	2	8049070
Pubmed	Deletion of collapsin response mediator protein 4 results in abnormal layer thickness and elongation of mitral cell apical dendrites in the neonatal olfactory bulb.	DPYSL3 TBX21	1.12e-05	2	117	2	26739921
Pubmed	Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.	PAPSS2 PAPSS1	1.12e-05	2	117	2	22242175
Pubmed	mRNAs for activin receptors II and IIB are expressed in mouse oocytes and in the epiblast of pregastrula and gastrula stage mouse embryos.	ACVR2A ACVR2B	1.12e-05	2	117	2	7748787
Pubmed	Elevated expression of ASF1B correlates with poor prognosis in human lung adenocarcinoma.	ASF1B ASF1A	1.12e-05	2	117	2	33576264
Pubmed	A quantitative trait locus for SBP maps near KCNB1 and PTGIS in a population isolate.	PTGIS KCNB1	1.12e-05	2	117	2	19265782
Pubmed	Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells.	CFH CFHR3	1.12e-05	2	117	2	34819935
Pubmed	Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.	PAPSS2 PAPSS1	1.12e-05	2	117	2	9771708
Pubmed	Formation and activation by phosphorylation of activin receptor complexes.	ACVR2A ACVR2B	1.12e-05	2	117	2	8721982
Pubmed	Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass.	ACVR2A ACVR2B	1.12e-05	2	117	2	28659341
Pubmed	A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.	CFH CFHR3	1.12e-05	2	117	2	26490391
Pubmed	Structure of the mouse activin receptor type II gene.	ACVR2A ACVR2B	1.12e-05	2	117	2	1318045
Pubmed	Characterization of type II activin receptors. Binding, processing, and phosphorylation.	ACVR2A ACVR2B	1.12e-05	2	117	2	8395525
Pubmed	Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.	ASF1B ASF1A	1.12e-05	2	117	2	24413054
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYCBP2 PTPN23 CDC42BPB ZNRF3 AMOT HELZ2 DIP2C	1.17e-05	225	117	7	12168954
Pubmed	Determinants of trophoblast lineage and cell subtype specification in the mouse placenta.	ACVR2A ACVR2B MAPK1	1.64e-05	15	117	3	15963972
Pubmed	Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas.	TBX21 GZMA GZMM	2.01e-05	16	117	3	24487434
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DPYSL3 DPYSL4 PTPN23 PARD3B DNAH7 NUP205 ACTR1A C2CD3 KLHL9 EIF2A TIMM44 BRWD1	3.19e-05	853	117	12	28718761
Pubmed	Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.	CFH CFHR3	3.36e-05	3	117	2	10781834
Pubmed	The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.	AMOT MAPK1	3.36e-05	3	117	2	21285250
Pubmed	Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation.	ACVR2A ACVR2B	3.36e-05	3	117	2	14738881
Pubmed	PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.	CCZ1B CCZ1	3.36e-05	3	117	2	32160108
Pubmed	PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport.	CDK18 SEC23A	3.36e-05	3	117	2	16091426
Pubmed	Characterization of isoforms of activin receptor-interacting protein 2 that augment activin signaling.	ACVR2A MAGI2	3.36e-05	3	117	2	16648306
Pubmed	Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy.	CFH CFHR3	3.36e-05	3	117	2	25205734
Pubmed	Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency.	CFH CFHR3	3.36e-05	3	117	2	18006700
Pubmed	Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.	ACVR2A ACVR2B	3.36e-05	3	117	2	12414726
Pubmed	Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells.	ATN1 FAT1	3.36e-05	3	117	2	19131340
Pubmed	Evaluation of CFH Y402H polymorphism and CFHR3/CFHR1 deletion in age-related macular degeneration patients from Brazil.	CFH CFHR3	3.36e-05	3	117	2	26942649
Pubmed	An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD).	CFH CFHR3	3.36e-05	3	117	2	20843825
Pubmed	A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes.	CFH CFHR3	3.36e-05	3	117	2	32321835
Pubmed	Assignment of ACVR2 and ACVR2B the human activin receptor type II and IIB genes to chromosome bands 2q22.2-->q23.3 and 3p22 and the human follistatin gene (FST) to chromosome 5q11.2 by FISH.	ACVR2A ACVR2B	3.36e-05	3	117	2	10702675
Pubmed	Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent.	CFH CFHR3	3.36e-05	3	117	2	20581873
Pubmed	Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome.	CFH CFHR3	3.36e-05	3	117	2	26163426
Pubmed	Association assessment of copy number polymorphism and risk of age-related macular degeneration.	CFH CFHR3	3.36e-05	3	117	2	21856016
Pubmed	Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1.	ASF1B ASF1A	3.36e-05	3	117	2	23178455
Pubmed	Regulation of muscle growth by multiple ligands signaling through activin type II receptors.	ACVR2A ACVR2B	3.36e-05	3	117	2	16330774
Pubmed	Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.	CFH CFHR3	3.36e-05	3	117	2	19531976
Pubmed	RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity.	ASF1B ASF1A	3.36e-05	3	117	2	35177609
Pubmed	Transcriptional regulation of human chromatin assembly factor ASF1.	ASF1B ASF1A	3.36e-05	3	117	2	17328667
Pubmed	Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication.	ASF1B ASF1A	3.36e-05	3	117	2	24598821
Pubmed	In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells.	ASF1B ASF1A	3.36e-05	3	117	2	18378699
Pubmed	Associations of CFH polymorphisms and CFHR1-CFHR3 deletion with blood pressure and hypertension in Chinese population.	CFH CFHR3	3.36e-05	3	117	2	22848687
Pubmed	Role of IFN-ks, IFN-ks related genes and the DEPDC5 gene in Hepatitis B virus-related liver disease.	ACP7 DEPDC5	3.36e-05	3	117	2	25032264
Pubmed	Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain.	DPYSL3 DPYSL4	3.36e-05	3	117	2	11771764
Pubmed	Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B.	ACVR2A ACVR2B	3.36e-05	3	117	2	26047946
Pubmed	Two factor H-related proteins from the mouse: expression analysis and functional characterization.	CFH CFHR3	3.36e-05	3	117	2	17028856
Pubmed	Localization of complement factor H gene expression and protein distribution in the mouse outer retina.	CFH CFHR3	3.36e-05	3	117	2	25684976
Pubmed	Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.	ASF1B ASF1A	3.36e-05	3	117	2	35136069
Pubmed	TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1.	ASF1B ASF1A	3.36e-05	3	117	2	17054786
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PTPRU MMP20 CDC42BPB PTK6 KCNB1 PRSS27 GZMM MAPK1 MMP17 SEC23B SEC23A	3.74e-05	730	117	11	34857952
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DCAKD MYCBP2 NSD2 LARP1 CHD9 PARD3B ACVR2B CDC42BPB PTK6 KLHL9 PCNX4 SBF2 RBM6 DIP2C GREB1 GPT2	4.01e-05	1489	117	16	28611215
Pubmed	Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice.	EIF2A SEC23B SEC23A	4.72e-05	21	117	3	26494538
Pubmed	TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.	ASF1B ASF1A	6.70e-05	4	117	2	20021694
Pubmed	Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway.	ASF1B ASF1A	6.70e-05	4	117	2	11897662
Pubmed	TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.	ACVR2A ACVR2B	6.70e-05	4	117	2	27696331
Pubmed	Development of a Highly Sensitive ELISA for Measurement of FSH in Serum, Plasma, and Whole Blood in Mice.	ACVR2A ACVR2B	6.70e-05	4	117	2	33475143
Pubmed	Activin A accelerates the progression of fetal oocytes throughout meiosis and early oogenesis in the mouse.	ACVR2A ACVR2B	6.70e-05	4	117	2	26083127
Pubmed	TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.	SEC23B SEC23A	6.70e-05	4	117	2	27551091
Pubmed	Murine FSH Production Depends on the Activin Type II Receptors ACVR2A and ACVR2B.	ACVR2A ACVR2B	6.70e-05	4	117	2	32270195
Pubmed	Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway.	PTK6 MAPK1	6.70e-05	4	117	2	25748447
Pubmed	CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome.	CFH CFHR3	6.70e-05	4	117	2	36793547
Pubmed	Replication stress interferes with histone recycling and predeposition marking of new histones.	ASF1B ASF1A	6.70e-05	4	117	2	20227376
Pubmed	Myostatin, follistatin and activin type II receptors are highly expressed in adenomyosis.	ACVR2A ACVR2B	6.70e-05	4	117	2	26086422
Pubmed	Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.	DPYSL3 DPYSL4	6.70e-05	4	117	2	10664068
Pubmed	Assignment of genes to regions of mouse chromosomes.	PAPSS2 TYR	6.70e-05	4	117	2	273256
Pubmed	Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.	CFH CFHR3	6.70e-05	4	117	2	24333077
Pubmed	A putative novel protein, DEPDC1B, is overexpressed in oral cancer patients, and enhanced anchorage-independent growth in oral cancer cells that is mediated by Rac1 and ERK.	MAPK1 DEPDC1B	6.70e-05	4	117	2	25091805
Pubmed	The Ulip family phosphoproteins--common and specific properties.	DPYSL3 DPYSL4	6.70e-05	4	117	2	9652388
Pubmed	Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines.	ASF1B ASF1A	6.70e-05	4	117	2	34529928
Pubmed	Generation of activin receptor type IIB isoform-specific hypomorphic alleles.	ACVR2A ACVR2B	6.70e-05	4	117	2	16991118
Pubmed	Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling.	DPYSL3 DPYSL4	6.70e-05	4	117	2	25358863
Pubmed	Regulation of myostatin activity and muscle growth.	ACVR2A ACVR2B	6.70e-05	4	117	2	11459935
Pubmed	Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly.	ASF1B ASF1A	6.70e-05	4	117	2	16980972
Pubmed	Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.	ASF1B ASF1A	6.70e-05	4	117	2	11470414
Pubmed	E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.	MYCBP2 NR1D1	6.70e-05	4	117	2	20534529
Pubmed	Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.	CCZ1B CCZ1	6.70e-05	4	117	2	20305638
Pubmed	Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases.	ASF1B ASF1A	6.70e-05	4	117	2	20016786
Pubmed	ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.	SEC23B SEC23A	6.70e-05	4	117	2	24069399
Pubmed	Expression of inhibin/activin proteins and receptors in the human hypothalamus and basal forebrain.	ACVR2A ACVR2B	6.70e-05	4	117	2	22296042
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SZT2 NSD2 LARP1 PLEKHG5 NUP205 KLHL9 AMOT FBXO41 DEPDC5	7.86e-05	529	117	9	14621295
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	CLUAP1 MYCBP2 CDC42BPB SETDB1 KLHDC3 BRWD1	7.87e-05	209	117	6	26389662
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	DPYSL3 BAG3 LARP1 NUP205 ACTR1A HELZ2 EIF2A	9.91e-05	315	117	7	26777405
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	CDK18 CNTNAP1 LARP1 CDC42BPB MAGI2 AMOT STARD9 FBXO41	1.08e-04	430	117	8	32581705
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ATN1 SZT2 NBEAL1 GRIK3 TENM2 PLA2R1 FAT1 HELZ2 ADAMTSL4	1.08e-04	552	117	9	10737800
Pubmed	High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice.	PARD3B NRP2	1.11e-04	5	117	2	16783640
GeneFamily	Type 2 receptor serine/threonine kinases	ACVR2A ACVR2B	1.34e-04	5	67	2	346
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	PARD3B TENM2 MAGI2 PLA2R1 FAT1 ZNRF3 PCNX4 SBF2	5.14e-06	212	117	8	M39221
Coexpression	ZHONG_PFC_C3_ASTROCYTE	DPYSL3 ASIC1 CNTNAP1 PTPRU ACVR2B ST8SIA3 CDC42BPB FBXO41 DIP2C MMP17	1.01e-05	389	117	10	M39102
Coexpression	GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP	NDST1 MYCBP2 CHD9 MAGI2 GBP4 HELZ2 LRRC75A	3.31e-05	200	117	7	M6186
Coexpression	GSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN	RIPPLY3 RBP3 DNAH7 TENM2 TYR KCNB1 GPT2	3.31e-05	200	117	7	M7508
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 PARD3B TENM2 NRP2 MAGI2 PLA2R1 FAT1 CPXM1	2.36e-09	194	117	9	43eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid\|bone_marrow / Manually curated celltypes from each tissue	DPYSL3 PRSS57 NSD2 ASF1B CTSG DEPDC1B LRRC75A	3.82e-07	173	117	7	5645a3b1e805c71d5d65fc8e4edc4e13208063fc
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH DPYSL3 FAT1 SEMA6D DIP2C GREB1 UBASH3B	5.38e-07	182	117	7	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFH DPYSL3 PTGIS PLA2R1 FAT1 HOXC9 SEMA6D	7.98e-07	193	117	7	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 TENM2 NRP2 PLA2R1 FAT1 CPXM1	8.26e-07	194	117	7	1374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	PCED1A NBEAL1 FAT1 SEMA6D STARD9 CPXM1 MMP17	1.01e-06	200	117	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PARD3B GRIK3 FAT1 SEMA6D UBASH3B CDH13	1.19e-06	129	117	6	6bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCell	Bac-SEP-Lymphocyte-T_NK-CD4_CTL\|Bac-SEP / Disease, Lineage and Cell Type	ANKRD13B CFH ZNRF3 GZMA GZMM CTSG	3.87e-06	158	117	6	4beed58bf58253253fc7e5009294b35e3bb8eae3
ToppCell	severe_influenza-CD4+_CTL\|World / disease group, cell group and cell class (v2)	ANKRD13B CFH TBX21 GZMA GZMM CTSG	5.14e-06	166	117	6	cdc3e200373718f26fe02ee516928097103f46e2
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SZT2 ACVR2A BCO2 PCNX4 GZMA DIP2C	6.09e-06	171	117	6	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH PARD3B DNAH7 MAGI2 FAT1 ZNRF3	7.66e-06	178	117	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 RIPPLY3 PARD3B PLA2R1 GBP4 KCNB1	8.17e-06	180	117	6	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-NK_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS57 TBX21 SLC34A1 GZMA GZMM MAPK1	8.17e-06	180	117	6	512c005567ad9c78cc5cc83862fc1219bcf49f60
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 RIPPLY3 PARD3B PLA2R1 GBP4 KCNB1	8.17e-06	180	117	6	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CFH TBX21 GZMA GZMM MAPK1 EIF2A	8.97e-06	183	117	6	983ca1342ddd365e1f1df32a456394b002b10e41
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 PARD3B TENM2 MAGI2 PLA2R1	8.97e-06	183	117	6	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	CFH PARD3B PTGIS MAGI2 FAT1 DIP2C	9.55e-06	185	117	6	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 PARD3B NRP2 MAGI2 FAT1	9.55e-06	185	117	6	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	CFH DPYSL3 PARD3B PTGIS MAGI2 GREB1	9.55e-06	185	117	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 PARD3B NRP2 MAGI2 FAT1	9.55e-06	185	117	6	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CYP1A1 PTK6 AMOT GZMA FBXO41 GPT2	9.84e-06	186	117	6	799903b68bc6f6205d004b44c603424b0d5f7c32
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SZT2 GRIK3 MAGI2 ZIC4 HOXC9 SEMA6D	9.84e-06	186	117	6	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CYP1A1 PTK6 AMOT GZMA GPT2 LRRC75A	9.84e-06	186	117	6	5cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|Mesenchymal_cells / Lineage and Cell class	B3GALT2 CFH PTGIS NRP2 FAT1 GBP4	1.01e-05	187	117	6	e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	B3GALT2 PARD3B TENM2 MAGI2 PLA2R1 CPXM1	1.01e-05	187	117	6	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPYSL3 MAGI2 FAT1 SEMA6D GREB1 UBASH3B	1.01e-05	187	117	6	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PARD3B NRP2 FAT1 SEMA6D UBASH3B	1.05e-05	188	117	6	8268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPPLY3 PARD3B NRP2 PLA2R1 KCNB1 CDH13	1.05e-05	188	117	6	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B NRP2 PLA2R1 FAT1 SEMA6D UBASH3B	1.05e-05	188	117	6	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH DPYSL3 PTGIS NRP2 FAT1 CPXM1	1.08e-05	189	117	6	46c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPPLY3 PARD3B NRP2 PLA2R1 KCNB1 CDH13	1.11e-05	190	117	6	a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PARD3B NRP2 FAT1 SEMA6D UBASH3B	1.11e-05	190	117	6	59720dfe9de1b980807644536c919d2a02ba69dd
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPPLY3 PARD3B NRP2 PLA2R1 KCNB1 CDH13	1.11e-05	190	117	6	25525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 ASIC1 GRIK3 CPXM1 GPT2 CDH13	1.11e-05	190	117	6	9b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 ASIC1 GRIK3 CPXM1 GPT2 CDH13	1.11e-05	190	117	6	d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCell	(1)_Osterolineage_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH DPYSL3 PTGIS NRP2 FAT1 CPXM1	1.21e-05	193	117	6	035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCell	normal_Lymph_Node-T/NK_cells-NK\|normal_Lymph_Node / Location, Cell class and cell subclass	PRSS57 TBX21 BCO2 GZMA GZMM MAPK1	1.33e-05	196	117	6	00ab4a1547752d419aa720b39b94a4ab2ede963a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 NRP2 PLA2R1 FAT1 CPXM1	1.33e-05	196	117	6	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	CFH DPYSL3 PARD3B PTGIS MAGI2 DIP2C	1.36e-05	197	117	6	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	CV-Severe-1\|CV / Virus stimulation, Condition and Cluster	TREX1 TBX21 NDFIP2 GBP4 GZMA HELZ2	1.40e-05	198	117	6	fc0e885e370ffb780eada62bb2b52065c2f8b26b
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	PARD3B PLEKHG5 PLA2R1 GBP4 AMOT HELZ2	1.40e-05	198	117	6	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-CD4+_CTL\|Bac-SEP / Disease, condition lineage and cell class	ANKRD13B CFH ZNRF3 GZMA GZMM CTSG	1.49e-05	200	117	6	78cce90288ee7224067f7b87c99c54737bed466d
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFH DPYSL3 PTGIS FAT1 SEMA6D PHOSPHO1	1.49e-05	200	117	6	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFH DPYSL3 PTGIS FAT1 SEMA6D PHOSPHO1	1.49e-05	200	117	6	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-MAIT\|Leuk-UTI / Disease, condition lineage and cell class	B3GALT2 CFH NBEAL1 FAM156A GZMA GZMM	1.49e-05	200	117	6	7e0d0f051c197c2c70080f039e1c4dd68db8e74f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH7 FAM156A GZMA GZMM MAMSTR	4.93e-05	151	117	5	0cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH7 FAM156A GZMA GZMM MAMSTR	4.93e-05	151	117	5	b545823113a3450c5f841f7de48bf0937593544f
ToppCell	facs-Spleen-nan-24m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 RIPPLY3 PTPRU MAGI2 GZMA	5.42e-05	154	117	5	bd283c2367afb99294e7576a0c0167eb7c69ad6b
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFH NR1D1 GZMA GZMM CTSG	5.42e-05	154	117	5	e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CFH TENM2 MAGI2 PLA2R1 CPXM1	5.59e-05	155	117	5	90e629681a72baacc7981b82883866a487638dbc
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 RIPPLY3 ZNRF3 GZMA GZMM	5.59e-05	155	117	5	7a16df1a40c7255c24dfb9a921b62871554c7b6d
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 RIPPLY3 ZNRF3 GZMA GZMM	5.59e-05	155	117	5	f51a12556ca0a3416a6cf0687f908fb4e752fb2f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 NRP2 MAGI2 FAT1	5.76e-05	156	117	5	dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 NRP2 MAGI2 FAT1	5.76e-05	156	117	5	abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 GBP4 ZNRF3 GZMA GZMM	6.12e-05	158	117	5	9f0987eaf1766aadb5714b68df7a5d310ea5a57a
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 GBP4 ZNRF3 GZMA GZMM	6.30e-05	159	117	5	94bc6ab248a8f02ccbc0facd24e0c7e9fda687d2
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TBX21 PLEKHG5 GZMA GREB1 CDH13	6.49e-05	160	117	5	955acb023ce4ccfac5073c9d693db87db3856187
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D\|390C / Donor, Lineage, Cell class and subclass (all cells)	CYP1A1 TBX21 GBP4 GZMA GZMM	6.69e-05	161	117	5	b60b4fd34a3ad4bf1813e6cc24aa7e04f9e53e4c
ToppCell	Influenza_Severe-gd_T\|World / Disease group and Cell class	CYP1A1 TBX21 STARD9 GZMA GZMM	6.69e-05	161	117	5	b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TBX21 NDFIP2 PHOSPHO1 GZMA GZMM	6.89e-05	162	117	5	19395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 TBX21 SEMA6D GZMM FBXO41	6.89e-05	162	117	5	b5b2cdbcc5bbfab52cc7d8a5504d34bb2e73771a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	B3GALT2 NDST1 GRIK3 PTPRU MMP17	6.89e-05	162	117	5	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 TBX21 SEMA6D GZMM FBXO41	6.89e-05	162	117	5	4f9cf67b4b00b1cf78eeb9be1c701d535021a61d
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 GBP4 ZNRF3 GZMA GZMM	7.30e-05	164	117	5	9fed5df40f50bde35db8bf89c291cbdc0e104112
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 GBP4 ZNRF3 GZMA GZMM	7.30e-05	164	117	5	e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCell	356C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PRSS57 NDFIP2 PARD3B SEMA6D CTSG	7.30e-05	164	117	5	b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCell	356C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PRSS57 NDFIP2 PARD3B SEMA6D CTSG	7.30e-05	164	117	5	f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFH NR1D1 GZMA GZMM TMEM102	7.51e-05	165	117	5	5e7ee76f3dcddbd1b560bacd043f9001b0c18b5f
ToppCell	Ionocyte-iono-3\|World / Class top	DCAKD PTPN23 ASF1B AMOT TMEM102	7.73e-05	166	117	5	9c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS57 PTPRU PAPSS2 GZMM CTSG	8.18e-05	168	117	5	260c768468dff51888f7a68e5424bb174dbaa759
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS57 PTPRU PAPSS2 GZMM CTSG	8.18e-05	168	117	5	18d7719a76620d5e5698f9ffd08b4ad4cb7c13f8
ToppCell	facs-Heart-RV-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 RIPPLY3 GBP4 CTSG CDH13	8.18e-05	168	117	5	831b000e26b4a7e7fdfa3988372e0281c45eadbb
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS57 TBX21 GZMA GZMM FBXO41	8.41e-05	169	117	5	96aafb687b34d4b59f75c24e176b0b442e864245
ToppCell	Influenza_Severe-gd_T\|Influenza_Severe / Disease group and Cell class	CYP1A1 TBX21 STARD9 GZMA GZMM	8.65e-05	170	117	5	59009c5a504ea8c6b4f6697299db219fd5edf7d6
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS57 PTPRU PAPSS2 ASF1B CTSG	8.89e-05	171	117	5	fea6ef6bbfebea2dd0f0360c7db7a5e858f15958
ToppCell	normal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T\|normal_Pleural_Fluid / Location, Cell class and cell subclass	TBX21 PHOSPHO1 GZMA GZMM MAPK1	8.89e-05	171	117	5	6be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS57 PTPRU PAPSS2 ASF1B CTSG	8.89e-05	171	117	5	f15594fd4d709920733de9376a391dedc62b65de
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-mature_NK_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBX21 GBP4 GZMA GZMM DEPDC1B	8.89e-05	171	117	5	a0462781d22c391b3c6c8a72586c385ac089ca5d
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBX21 GBP4 GZMA GZMM DEPDC1B	8.89e-05	171	117	5	85b655dc8a3cbf0e8097e951116490e326a795ac
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-NK_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS57 TBX21 BCO2 GZMA GZMM	9.13e-05	172	117	5	f3c16a62eba1ed190318beee131c71c5150b266a
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	B3GALT2 GZMA GZMM AOC3 DEPDC1B	9.13e-05	172	117	5	2b0333c21b7472194a7b9feb3de121da3340fc5b
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-MAIT\|Multiple_Sclerosis / Disease, Lineage and Cell Type	B3GALT2 CFH NR1D1 GZMA GZMM	9.13e-05	172	117	5	18bda0038cb37da6784e7bf7291272c108cfd9c5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH DPYSL3 TENM2 MAGI2 PLA2R1	9.13e-05	172	117	5	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD13B PRSS57 TBX21 GZMA GZMM	9.13e-05	172	117	5	86f52f486d67217fc1b8443ab362c975df2974a4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD13B PRSS57 TBX21 GZMA GZMM	9.13e-05	172	117	5	fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD13B PRSS57 TBX21 GZMA GZMM	9.13e-05	172	117	5	e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like\|blood / Manually curated celltypes from each tissue	CFH DNAH7 KCNB1 GZMA GZMM	9.64e-05	174	117	5	51be6f29308c01593978cbee92114151a5916c9c
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	B3GALT2 PCED1A PTGIS AMOT CDH13	9.91e-05	175	117	5	f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TENM2 MAGI2 PLA2R1 FAT1 ZNRF3	9.91e-05	175	117	5	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT\|blood / Manually curated celltypes from each tissue	CFH DNAH7 KCNB1 GZMA GZMM	9.91e-05	175	117	5	b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-2\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TBX21 BAG3 GBP4 GZMA UBASH3B	1.02e-04	176	117	5	1870860a9ebe7a655c4ea8898427e1097ee23113
ToppCell	10x3'2.3-week_12-13-Lymphocytic_T-T_NK-NK_T_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HIVEP1 PLEKHG5 GZMA GZMM ASF1A	1.05e-04	177	117	5	e1ba7e17af2c54d3c78cdf85882168c5b896e453
ToppCell	IIF-Lymphocyte-T_NK-MAIT\|IIF / Disease, Lineage and Cell Type	B3GALT2 CFH NR1D1 GZMA GZMM	1.07e-04	178	117	5	be777ebef8f09a1a16fcee8fc69a65ab295b6e1d
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1A1 RIPPLY3 PTPRU PTGIS NRP2	1.07e-04	178	117	5	ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1A1 RIPPLY3 PTPRU PTGIS NRP2	1.07e-04	178	117	5	ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1A1 RIPPLY3 PTPRU PTGIS NRP2	1.07e-04	178	117	5	87b04753650e45f12299c8456fb980d6c0d5961c
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	CYP1A1 PTK6 AMOT FBXO41 GPT2	1.10e-04	179	117	5	ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PARD3B TENM2 MAGI2 PLA2R1	1.10e-04	179	117	5	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	COPD-Epithelial-PNEC\|Epithelial / Disease state, Lineage and Cell class	DPYSL3 GRIK3 ST8SIA3 SLC18A1 GREB1	1.10e-04	179	117	5	988d0853c391da1e5004f73f3678047418d3f6d3
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	B3GALT2 CFH NR1D1 BCO2 DIP2C	1.10e-04	179	117	5	d18a520568cf4b031972d3dd7d4d4bd073ac1fea
Drug	Clioquinol [130-26-7]; Up 200; 13uM; MCF7; HT_HG-U133A	CYP1A1 ASIC1 CNTNAP1 PIWIL2 NR1D1 DNAH7 MAGI2 SEMA6D ADAMTSL4	6.18e-07	190	117	9	5623_UP
Disease	congenital dyserythropoietic anemia type II (implicated_via_orthology)	SEC23B SEC23A	1.45e-05	2	113	2	DOID:0111401 (implicated_via_orthology)
Disease	craniolenticulosutural dysplasia (implicated_via_orthology)	SEC23B SEC23A	1.45e-05	2	113	2	DOID:0070307 (implicated_via_orthology)
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP1 ACVR2A ACVR2B	1.52e-05	13	113	3	DOID:0050787 (implicated_via_orthology)
Disease	endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase measurement	CFH CFHR3	4.35e-05	3	113	2	EFO_0801568
Disease	anaphase-promoting complex subunit 7 measurement	CFH CFHR3	4.35e-05	3	113	2	EFO_0801381
Disease	HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1	CFH CFHR3	4.35e-05	3	113	2	C2749604
Disease	HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1	CFH CFHR3	4.35e-05	3	113	2	235400
Disease	neuropilin-2 measurement	PARD3B NRP2	4.35e-05	3	113	2	EFO_0801836
Disease	Hemolytic uremic syndrome, atypical, susceptibility to, 1	CFH CFHR3	4.35e-05	3	113	2	cv:C2749604
Disease	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement	CFH CFHR3	8.68e-05	4	113	2	EFO_0803292
Disease	Weissenbacher-Zweymuller syndrome (implicated_via_orthology)	ACVR2A MAPK1	8.68e-05	4	113	2	DOID:4258 (implicated_via_orthology)
Disease	Meningococcal Infections	CFH CFHR3	8.68e-05	4	113	2	C0025303
Disease	Roberts syndrome (implicated_via_orthology)	SEC23B SEC23A	8.68e-05	4	113	2	DOID:5325 (implicated_via_orthology)
Disease	potassium voltage-gated channel subfamily F member 1 measurement	CFH SLC34A1	1.44e-04	5	113	2	EFO_0802890
Disease	fructose-1,6-bisphosphatase isozyme 2 measurement	CFH PCNX4	1.44e-04	5	113	2	EFO_0802556
Disease	white matter hyperintensity measurement	DCAKD NBEAL1 QRICH2 TENM2 ZNF16 KCNB1 SBF2	1.68e-04	302	113	7	EFO_0005665
Disease	primary ciliary dyskinesia (is_implicated_in)	DNAH7 BRWD1	2.16e-04	6	113	2	DOID:9562 (is_implicated_in)
Disease	bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 measurement	CFH NDST1	3.01e-04	7	113	2	EFO_0802332
Disease	autism spectrum disorder (implicated_via_orthology)	NDST1 CNTNAP1 CHD9 NRP2 MAPK1	3.05e-04	152	113	5	DOID:0060041 (implicated_via_orthology)
Disease	membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 measurement	CFH MAGI2	4.01e-04	8	113	2	EFO_0802739
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	CFH CFHR3	4.01e-04	8	113	2	DOID:0080301 (is_implicated_in)
Disease	Atypical hemolytic-uremic syndrome	CFH CFHR3	5.14e-04	9	113	2	cv:C2931788
Disease	C-C motif chemokine 25 measurement	MAMSTR TIMM44	5.14e-04	9	113	2	EFO_0008050
Disease	Hemolytic-uremic syndrome	CFH CFHR3	5.14e-04	9	113	2	cv:C0019061
Disease	Situs ambiguous	ACVR2B DNAH9	5.14e-04	9	113	2	C1167664
Disease	bitter beverage consumption measurement	CYP1A1 ACVR2B MAGI2	5.63e-04	42	113	3	EFO_0010089
Disease	Psychotic Disorders	SLC39A3 GRIK3 BCL9 TYR	6.26e-04	101	113	4	C0033975
Disease	Marfan syndrome (implicated_via_orthology)	ACVR2A ACVR2B	6.41e-04	10	113	2	DOID:14323 (implicated_via_orthology)
Disease	Atypical Hemolytic Uremic Syndrome	CFH CFHR3	6.41e-04	10	113	2	C2931788
Disease	diet measurement	CYP1A1 GRIK3 TENM2 PTK6 TYR MAGI2 ZIC4 SEMA6D MAMSTR RBM6 DEPDC5 CDH13	7.00e-04	1049	113	12	EFO_0008111
Disease	unipolar depression	CFH CNTNAP1 GRIK3 CDC42BPB DNAH7 TENM2 PTGIS TYR MAGI2 FAT1 SEMA6D KCNB1 CDH13	7.25e-04	1206	113	13	EFO_0003761
Disease	neuroticism measurement	HIVEP1 NBEAL1 GRIK3 ACVR2A PTGIS TYR SEMA6D KCNB1 SBF2 DIP2C SEC23B	7.46e-04	909	113	11	EFO_0007660
Disease	Situs Inversus	ACVR2B DNAH9	7.82e-04	11	113	2	C0037221
Disease	pneumonia	ACVR2A TRAPPC12 HELZ2	7.84e-04	47	113	3	EFO_0003106
Disease	Drug habituation	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C0013170
Disease	Drug abuse	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C0013146
Disease	Prescription Drug Abuse	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C4316881
Disease	Substance-Related Disorders	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C0236969
Disease	Drug Use Disorders	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C0013222
Disease	Drug Dependence	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C1510472
Disease	Substance Dependence	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C0038580
Disease	Substance Use Disorders	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	TENM2 PLA2R1 SEMA6D CDH13	1.02e-03	115	113	4	C0029231
Disease	Substance abuse problem	TENM2 PLA2R1 SEMA6D CDH13	1.05e-03	116	113	4	C0740858
Disease	membranous glomerulonephritis (biomarker_via_orthology)	CFH PTPRU	1.28e-03	14	113	2	DOID:10976 (biomarker_via_orthology)
Disease	response to 5-fluorouracil, response to cyclophosphamide, chemotherapy-induced alopecia, response to doxorubicin	BCL9 CDH13	1.28e-03	14	113	2	EFO_0005400, GO_0036275, GO_1902518, GO_1902520
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	CCZ1B CCZ1	1.28e-03	14	113	2	DOID:3753 (implicated_via_orthology)
Disease	Situs ambiguus	ACVR2B DNAH9	1.48e-03	15	113	2	C0266642
Disease	cortex volume change measurement	PARD3B MAGI2	1.48e-03	15	113	2	EFO_0021500
Disease	response to olanzapine	HIVEP1 CDH13	1.48e-03	15	113	2	GO_0097333
Disease	neuroticism measurement, cognitive function measurement	HIVEP1 NBEAL1 GRIK3 ACVR2A PTPRU TYR SEMA6D CDH13	1.53e-03	566	113	8	EFO_0007660, EFO_0008354
Disease	Intellectual Disability	NDST1 TREX1 ATN1 NSD2 PTPN23 EIF2A GPT2	1.70e-03	447	113	7	C3714756
Disease	systemic lupus erythematosus (is_implicated_in)	CFH CYP1A1 TREX1	1.75e-03	62	113	3	DOID:9074 (is_implicated_in)
Disease	Age-related macular degeneration	CFH CFHR3	2.14e-03	18	113	2	cv:C0242383
Disease	hemifacial microsomia	DCAKD PARD3B	2.38e-03	19	113	2	MONDO_0015398
Disease	Bipolar Disorder	SLC39A3 BCL9 NR1D1 MAGI2 SLC18A1 STARD9 MAPK1	2.45e-03	477	113	7	C0005586
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	KCNB1 DEPDC5 GREB1	2.59e-03	71	113	3	EFO_0004735, EFO_0007965
Disease	risk-taking behaviour	HIVEP1 PARD3B TENM2 MAGI2 ACTR1A ZIC4 SEMA6D MAPK1 CDH13	2.72e-03	764	113	9	EFO_0008579
Disease	sleep duration	MYCBP2 MMP20 TENM2 MAGI2 SEMA6D CDH13	2.75e-03	362	113	6	EFO_0005271
Disease	response to bronchodilator, FEV/FEC ratio	CFH PARD3B GRIK3 TENM2 NUP205 SEMA6D UBASH3B DEPDC1B CDH13	2.77e-03	766	113	9	EFO_0004713, GO_0097366
Disease	tissue factor measurement	CFH MAMSTR	2.91e-03	21	113	2	EFO_0010623
Disease	nephrosis (biomarker_via_orthology)	CFH PTPRU	3.19e-03	22	113	2	DOID:2527 (biomarker_via_orthology)
Disease	Liver carcinoma	CYP1A1 ZIC4 BCO2 ASF1B DEPDC5 DEPDC1B CDH13	3.43e-03	507	113	7	C2239176
Disease	age at first sexual intercourse measurement	TENM2 NUP205 ZIC4 SEMA6D DEPDC1B BRWD1	3.63e-03	383	113	6	EFO_0009749
Disease	Anhedonia	SETDB1 MAPK1	3.80e-03	24	113	2	C0178417
Disease	Cancer of Head	FAT1 MAPK1	3.80e-03	24	113	2	C0751177
Disease	Head Neoplasms	FAT1 MAPK1	3.80e-03	24	113	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	FAT1 MAPK1	3.80e-03	24	113	2	C0887900

Protein segments in the cluster

Peptide	Gene	Start	Entry
QREGTYHFRMTILPP	GPT2	486	Q8TD30
PGRTEGQLMRYQHPP	AMOT	271	Q4VCS5
AREFSHMLSRPVPGY	CNTNAP1	1021	P78357
MFGYGRVPFALPLHR	ADAMTSL4	156	Q6UY14
HYEMATGRPLFPGST	CDK18	331	Q07002
LVGPVPAGRHMFVFQ	ASF1A	61	Q9Y294
THGQVGTRRYMAPEV	ACVR2A	356	P27037
LHAVPRGMYDGPVFD	DPYSL3	491	Q14195
GGNEVTPHSRPYMVL	GZMA	31	P12544
IIGGREVIPHSRPYM	GZMM	26	P51124
LSEYARPHVMSPGNR	ATN1	886	P54259
PSMNPDGYEIAYHRG	CPXM1	401	Q96SM3
MEAYVPGFAHIPRGT	CUEDC2	61	Q9H467
MEHRIVGPGPYRATR	DEPDC1B	1	Q8WUY9
YHENMRRPYFPVAVG	CFH	336	P08603
VGRGRYPMFPHHSRS	ANGEL2	16	Q5VTE6
NRPIFREGPYIGHVM	CDH13	241	P55290
RAEVPVQMPYGFHGT	BCO2	561	Q9BYV7
YMRDVTVERHGGPLP	AOC3	151	Q16853
VHMPGKRPFGQSFVY	NBEAL1	671	Q6ZS30
ISVRPYQHGMVPPGR	QRICH2	836	Q9H0J4
ELMAGPGHFNPYRYV	CYP1A1	176	P04798
RYFPTERGQPMVHGA	PTPN23	1301	Q9H3S7
MGSYLGVAHQRPPQR	NUP205	476	Q92621
GSREMPYTNPRGPVH	ACP7	351	Q6ZNF0
PVGRGMFTLFSYHPV	ANAPC1	1081	Q9H1A4
KPGTHPMSYEGRRQD	ANKRD13B	536	Q86YJ7
ESMLHVRPGGYTPQR	DEPDC5	581	O75140
PGYQRHFEAPAVESM	FAT1	4521	Q14517
PEMVRGQVFDVGPRY	MAPK1	11	P28482
NFYIVGRDPAGMPHP	PAPSS2	506	O95340
HQRMPAYQETGRPGP	PARD3B	1166	Q8TEW8
VTQTPHYMRRHPGGD	LARP1	646	Q6PKG0
GPQPHLGADTRYMRT	HOXC9	81	P31274
GPRPVVYMQHALFAD	LIPN	76	Q5VXI9
HMAPYAVGREARISP	FAM156A	101	Q8NDB6
ERPPPVMVNGRHNYE	MAGI2	531	Q86UL8
TVPRPSHMDYGNRAE	GREB1	1316	Q4ZG55
MAFAGFVSERGPPYR	SBF2	411	Q86WG5
AGRAGAGMPPYHRRV	LRRC75A	41	Q8NAA5
AGMPPYHRRVGMVQE	LRRC75A	46	Q8NAA5
DNMAPSPGHILRVYG	PCNX4	986	Q63HM2
GQHWGPVVHRGMPRY	PCED1A	396	Q9H1Q7
GMPRYVPNSPYHVRR	PCED1A	406	Q9H1Q7
VPNSPYHVRRMGGPC	PCED1A	411	Q9H1Q7
THQARVFPYMEGDRG	NSD2	931	O96028
GNMHYDTPDIRRFDP	NRP2	551	O60462
GAFGFQHPVRVYLPM	RIPPLY3	71	P57055
PARYRRGFIHNGIMV	NDST1	466	P52848
APMDAPRYQHGIAVI	KLHL9	331	Q9P2J3
MGERTLHAAVPTPGY	GBP4	1	Q96PP9
FSHMGLYVDPQGRRA	CDC42BPB	1441	Q9Y5S2
LLHEMFSRGQVPYPG	PTK6	376	Q13882
FSRGQVPYPGMSNHE	PTK6	381	Q13882
VPYPGMSNHEAFLRV	PTK6	386	Q13882
GSRQEPMPAYDRHRV	PTPRU	916	Q92729
GHVMRGTAFAYVPSP	SLC34A1	21	Q06495
TVLFRMQAQPPGYRH	ACP2	401	P11117
MQAQPPGYRHVADGE	ACP2	406	P11117
EPGRMDHHQPGTGRY	NDFIP2	91	Q9NV92
NMYPHGRSGRTVQEI	NR1D1	421	P20393
NFYIVGRDPAGMPHP	PAPSS1	516	O43252
LPPRHNYFTGYLMRG	B3GALT2	271	O43825
RGLYDGPVHEVMVPA	DPYSL4	496	O14531
LVGPVPAGRHMFVFQ	ASF1B	61	Q9NVP2
HPGYVEDLGAFIPRM	CHD9	2516	Q3L8U1
GGLFHENMRRPYFPV	CFHR3	31	Q02985
PVLGMYHDPLRNRGS	KCNB1	686	Q14721
RFVFPVQFGGPMIEH	C2CD3	621	Q4AC94
VDVMARHVVQPGYPA	DCAKD	31	Q8WVC6
EHPQQEYGMGPRPFL	BCL9	771	O00512
SPIRAEMPGNLQHYG	CCZ1	266	P86791
GGGRNPVTPRYMRHF	DNAH7	2096	Q8WXX0
SPIRAEMPGNLQHYG	CCZ1B	266	P86790
QPPGRGVLSMHGLTY	DIP2C	671	Q9Y2E4
PNYVGRPKHVRVMAG	ACTR1A	36	P61163
LHRGRPPEMPVNYGS	BRWD1	131	Q9NSI6
RMREHHVGPAVPNTY	FBXO41	376	Q8TF61
HQYMPPEPRQGSRAD	MAMSTR	101	Q6ZN01
IRGQAPVVPYMRYGH	KLHDC3	66	Q9BQ90
IIGGRESRPHSRPYM	CTSG	21	P08311
PPREGAYIHGLFMEG	DNAH9	4391	Q9NYC9
RGSEGLYMVNGPPHF	EIF2A	11	Q9BY44
FPQHFLGLSGMPRRY	MT-CO1	426	P00395
GMPHVIRIGGIFEYA	GRIK3	31	Q13003
VSGGHPEATPLRVMY	HELZ2	591	Q9BYK8
FHVYPQPGMQRFRTE	BAG3	111	O95817
RGFQMQGPPRTIYDF	MMP20	371	O60882
TPYMYAGTGPEHVRD	GARIN2	216	Q8N9W8
PRGYLAATMQFVPGH	SZT2	2021	Q5T011
LRMARPGGPEHNEYA	SZT2	3126	Q5T011
YRDVDHRLPGSQMFG	RBM6	406	P78332
AAHSIMRPYYQGPVG	MMP17	261	Q9ULZ9
VYHDPSRGMRSVVGF	PIWIL2	746	Q8TC59
YGFGLMQPEHDVPVR	PTGIS	481	Q16647
TPHSRPYMASVRFGG	PRSS57	41	Q6UWY2
SPGAPRMYMFHAGFR	ST8SIA3	46	O43173
PFMGGARGHALYVEP	SLC39A3	136	Q9BRY0
RRGLPPSHAQYDFME	TENM2	496	Q9NT68
RGPLVFAGPIFMNHR	MYCBP2	876	O75592
REHPEMGPYVQGLSQ	STARD9	176	Q9P2P6
PRYSGGCVAMRGRHP	PLA2R1	611	Q13018
PMPRYIDTEHGGSQA	SEC23A	701	Q15436
RFPMPRYINTEHGGS	SEC23B	701	Q15437
FHGMLERAPAEPSYR	SETDB1	551	Q15047
RGHPAGMTYAANILP	ASIC1	501	P78348
PPGDTHGQVGTRRYM	ACVR2B	351	Q13705
LGYPRHISMENFRTP	CLUAP1	16	Q96AJ1
MHYDGHVRFDLPPQG	PLEKHG5	1	O94827
FSHMELPGPRYSTQR	RBP3	521	P10745
HVYPGRRGSMVPFSM	TRAPPC12	466	Q8WVT3
GARQLVQPGPHAMYA	PRSS27	91	Q9BQR3
RGPHYDAGFTLLVPM	TMEM102	111	Q8N9M5
APIGHNRESYMVPFI	TYR	416	P14679
GGDVAFPRRGYPMHR	PHOSPHO1	216	Q8TCT1
HGPGAFFRYMRQPIK	ZIC4	111	Q8N9L1
PHGSTYQMRRPGGEL	TIMM44	31	O43615
QHRPPRQPTEYFDMG	ZNRF3	206	Q9ULT6
TEERPHPYDMGGQSF	ZNF16	176	P17020
MPHSLPQRSGGFRDY	UBASH3B	421	Q8TF42
PGVPMTSLERQRGYH	SEMA6D	951	Q8NFY4
AHARPFGTIRPMYGV	TREX1	221	Q9NSU2
QSRTPYNMVPVGGIH	HIVEP1	2391	P15822
EGSMPGNRLYVHPDS	TBX21	211	Q9UL17
FVGPLTNRIGYHIPM	SLC18A1	156	P54219